Sensors, Vol. 16, Pages 180: A Personal, Distributed Exposimeter: Procedure for Design, Calibration, Validation, and Application
This paper describes, for the first time, the procedure for the full design, calibration, uncertainty analysis, and practical application of a personal, distributed exposimeter (PDE) for the detection of personal exposure in the Global System for Mobile Communications (GSM) downlink (DL) band around 900 MHz (GSM 900 DL). The PDE is a sensor that consists of several body-worn antennas. The on-body location of these antennas is investigated using numerical simulations and calibration measurements in an anechoic chamber. The calibration measurements and the simulations result in a de...περισσότερα »
Aerospace, Vol. 3, Pages 5: Target Tracking in 3-D Using Estimation Based Nonlinear Control Laws for UAVs
This paper presents an estimation based backstepping like control law design for an Unmanned Aerial Vehicle (UAV) to track a moving target in 3-D space. A ground-based sensor or an onboard seeker antenna provides range, azimuth angle, and elevation angle measurements to a chaser UAV that implements an extended Kalman filter (EKF) to estimate the full state of the target. A nonlinear controller then utilizes this estimated target state and the chaser's state to provide speed, flight path, and course/heading angle commands to the chaser UAV. Tracking performance with respect to meas...περισσότερα »
Gels, Vol. 2, Pages 7: Supramolecular Assembly of pH-Sensitive Triphenylene Derived π-Gelators and Their Application as Molecular Template for the Preparation of Silica Nanotubes
The gelation properties and mode of self-assembly of six asymmetrical hexaether triphenylene derivatives mono-functionalized with carboxylic and primary amine groups were investigated. The presence of a carboxylic and amine group attached to the triphenylene core generated stable, thermo- and pH-sensitive supramolecular π-organogels with a reversible response to both stimuli. In order to understand the gelation process, we studied the effect of the spacer length and found a different gelation scope for the acid and basic derivatives that accounts for a different supramolecular sel... περισσότερα »
Diagnostics, Vol. 6, Pages 8: Interobserver and Intraobserver Reproducibility with Volume Dynamic Contrast Enhanced Computed Tomography (DCE-CT) in Gastroesophageal Junction Cancer
The purpose of this study was to assess inter- and intra-observer reproducibility of three different analytic methods to evaluate quantitative dynamic contrast-enhanced computed tomography (DCE-CT) measures from gastroesophageal junctional cancer. Twenty-five DCE-CT studies with gastroesophageal junction cancer were selected from a previous longitudinal study. Three radiologists independently reviewed all scans, and one repeated the analysis eight months later for intraobserver analysis. Review of the scans consisted of three analysis methods: (I) Four, fixed small sized regions o...περισσότερα »
Comparison of Histopathological Effects of Thymoquinone and Local Nasal Corticosteroids in Allergic Rhinitis in a Rabbit Model
*Background/Aims:* In this study, we aimed to evaluate the histopathological effects of thymoquinone treatment of the nasal mucosa in a rabbit model of allergic rhinitis, and we compared its effects with those of nasal mometasone furoate. *Methods:* A total of 24 male New Zealand rabbits were used. The animals were randomly assigned to one of four groups. Group 1 received no treatment, while group 2 underwent ovalbumin (OVA) sensitization only. Group 3 was the study group; after OVA sensitization, the rabbits were treated with intranasal thymoquinone. The group 4 rabbits received mo...περισσότερα »
Comparison of Histopathological Effects of Thymoquinone and Local Nasal Corticosteroids in Allergic Rhinitis in a Rabbit Model
*Background/Aims:* In this study, we aimed to evaluate the histopathological effects of thymoquinone treatment of the nasal mucosa in a rabbit model of allergic rhinitis, and we compared its effects with those of nasal mometasone furoate. *Methods:* A total of 24 male New Zealand rabbits were used. The animals were randomly assigned to one of four groups. Group 1 received no treatment, while group 2 underwent ovalbumin (OVA) sensitization only. Group 3 was the study group; after OVA sensitization, the rabbits were treated with intranasal thymoquinone. The group 4 rabbits received mo...περισσότερα »
Unilateral facial nerve palsy in an adolescent with Guillain-Barre syndrome
Rare encounter of unilateral facial nerve palsy in an adolescent with Guillain-Barre syndrome: Unilateral facial nerve palsy is rarely encountered in Guillain-Barré syndrome (GBS). We report a case of an adolescent girl who presented with peripheral ascending weakness, preceded by *Campylobacter jejuni* infection. After treatment with intravenous immunoglobulin, the peripheral weakness improved. Electro-diagnostic testing confirmed axonal dysfunction and the patient was positive for antiganglioside antibodies. However, the patient developed unilateral left-sided facial weakness. Sh... περισσότερα »
Osteomalacia with low alkaline phosphatase
Osteomalacia with low alkaline phosphatase: a not so rare condition with important consequences: Hypophosphatasia is a genetic disorder, characterised by a dysfunctional tissue-non-specific isoenzyme of alkaline phosphatase that impacts bone metabolism and predisposes to osteomalacia or rickets. The clinical presentation is very diverse, depending on the age of onset and the severity of the disease. Several forms of hypophosphatasia are recognised. We present a case of a 50-year-old woman with low impact fractures and loss of teeth at a young age. She also had a low alkaline phosph... περισσότερα »
High-velocity facial gunshot wounds: multidisciplinary care from prehospital to discharge
High-velocity facial gunshot wounds: multidisciplinary care from prehospital to discharge: A case is presented in which a high velocity rifle (shotgun) was fired into the inferior part of a patient's face in an attempted suicide causing widespread trauma to the inferior and left side of the patient's face. He presented to his general practitioner where an ambulance was called. The patient is followed from prehospital care (air ambulance) to resuscitation in accident and emergency and through the first stages of reconstructive surgery. The article focuses on the multidisciplinary ap... περισσότερα »
Spontaneous spinal subarachnoid haemorrhage: a not so benign disease with devastating results
Spontaneous spinal subarachnoid haemorrhage: a not so benign disease with devastating results: Description A 67-year-old male presented with sudden right hemiplegia. One hour before he had complained of mild cervicalgia, but physical examination at the time revealed neither neurological deficits nor stiffness of the neck. He had been admitted to the hospital the day before due to acute biliary pancreatitis, with elevated transaminases but normal blood coagulation testing. He had no history of trauma. Twenty minutes after the onset plegia on the left leg and moderate paresis on the l... περισσότερα »
Use of butane-isobutane refrigerant spray in the management of a mucocoele in a visually impaired child
Use of butane-isobutane refrigerant spray in the management of a mucocoele in a visually impaired child: Mucocoeles are commonly observed lesions in children and young adults. Conventional management using a scalpel aims at enucleation, requiring psychological preparation of the parent as well as the child because of inherent fear and apprehension towards surgery. This is still more complex in children with visual impairment. The other management techniques are laser, cryotherapy and micromarsupialisation, management strategies that, being painless and tolerable, reduce the anxiety...περισσότερα »
Pilonidal sinus of the chin
Pilonidal sinus of the chin: mistreated as a dental fistula: Pilonidal sinus is a chronic inflammatory condition associated with penetration of hair particles into the skin. It is rare in the chin area and, to our knowledge, there is only one such reported case. A 56-year-old man was previously admitted to a private clinic, with a hard mass on his anterior buccal sulcus. Three of the patient's teeth were extracted as the swelling was thought to be associated with a dental infection. Because the fistula did not resolve, the patient was referred to our department. Following radiologi... περισσότερα »
Epinephrine-resistant angioedema
'Epinephrine-resistant angioedema: A man in his 60s was brought to the emergency department, with airway compromise and dysarthria due to a grossly enlarged tongue. As he was on a current course of antibiotics, he was treated for a likely antibiotic-associated allergic reaction. However, as he failed to improve with intramuscular and nebulised epinephrine, another cause of his symptoms was sought. Further discussion revealed a history of chronic lymphocytic leukaemia (CLL), which had recently relapsed. Investigations were ordered to confirm that the symptoms were due to acquired an...περισσότερα »
Left atrial impression by a dilated oesophagus in a patient with limited cutaneous systemic sclerosis
Left atrial impression by a dilated oesophagus in a patient with limited cutaneous systemic sclerosis: Description A 38-year-old woman, a diagnosed case of limited cutaneous systemic sclerosis (lcSSc) presented for a routine transthoracic echocardiography (TTE) examination. Her medical history consisted of Raynaud's phenomenon, coarse and thickened skin on extremities and oesophageal symptoms in the form of dysphagia to both, solids and liquids, heartburn and regurgitation. Her TTE revealed normally functioning ventricles and no evidence of pulmonary artery hypertension. A mass was ...περισσότερα »
Combined ab interno trabeculotomy and lens extraction: a novel management option for combined uveitic and chronic narrow angle raised intraocular pressure
Minimally invasive glaucoma surgery is a developing area that has the potential to replace traditional glaucoma surgery, with its known risk profile, but at present there are no randomised controlled data to validate its use. We report on a case where sequential bilateral combined *ab interno* trabeculotomy and lens extraction surgery was performed on a 45-year-old woman with combined uveitic and chronic narrow angle raised intraocular pressure. Maximal medical management alone could not control the intraocular pressure. At 12-month follow-up, the patient had achieved stable intra... περισσότερα »
Cornelia de Lange and Ehlers-Danlos: comorbidity of two rare syndromes
We present a case of a young adult with both Cornelia de Lange syndrome and Ehlers-Danlos syndrome. The patient showed non-verbal autism, intellectual disability and severe/intractable self-harming behaviours that led to a life-threatening complication (ie, septicaemia). A significant reduction in the self-harming behaviours was attained in a multidisciplinary neurobehavioural inpatient unit after addressing all causes of somatic pains, managing pain using level II and III analgesics, stabilising the patient's mood, limiting the iatrogenic effects of multiple prescriptions and off... περισσότερα »
Colonic metastasis in mucoepidermoid carcinoma of the parotid
Alexandros G. SfakianakisστοHead,Neck,Brain,Cervical Spine and Esophageal Cancers by Alexandros G. SfakianakisΠριν από 5 δευτερόλεπτα
Colonic metastasis in mucoepidermoid carcinoma of the parotid: a rare occurrence: We present a case of intermediate-grade mucoepidermoid carcinoma of the parotid with late local recurrence and colonic metastasis. A 69-year-old man who had undergone right total conservative parotidectomy followed by adjuvant radiotherapy for intermediate-grade mucoepidermoid carcinoma 10 years prior, presented with a recurrent swelling in the postoperative site and cardiac failure. On evaluation, he was found to have severe anaemia with positive stool occult blood. Colonoscopic evaluation revealed ...περισσότερα »
Laryngopyocoele: an unusual cause of airway obstruction
Laryngopyocoele: an unusual cause of airway obstruction: Description An 88-year-old woman presented with a 2-day history of dysphagia, hoarseness and inspiratory stridor. Examination revealed well-defined soft lobulated masses anteriorly and to the right of her neck. Flexible-nasendoscopy demonstrated a large mass displacing the right false-cord and compressing the epiglottis. She had good air entry to all lung fields and laboratory testing revealed a slight rise in white cell counts only. With radiological investigation pending, she became increasingly stridulous with markedly inc... περισσότερα »
Cornelia de Lange and Ehlers-Danlos: Non-verbal autism, intellectual disability and severe/intractable self-harming behaviours that led to a life-threatening complication (ie, septicaemia)
Cornelia de Lange and Ehlers-Danlos: comorbidity of two rare syndromes: We present a case of a young adult with both Cornelia de Lange syndrome and Ehlers-Danlos syndrome. The patient showed non-verbal autism, intellectual disability and severe/intractable self-harming behaviours that led to a life-threatening complication (ie, septicaemia). A significant reduction in the self-harming behaviours was attained in a multidisciplinary neurobehavioural inpatient unit after addressing all causes of somatic pains, managing pain using level II and III analgesics, stabilising the patient's ... περισσότερα »
Neuroprotective effects of hydrogen sulfide against early brain injury and secondary cognitive deficits following subarachnoid hemorrhage
Neuroprotective effects of hydrogen sulfide against early brain injury and secondary cognitive deficits following subarachnoid hemorrhage: Abstract Although the neuroprotective effects of hydrogen sulfide (H2S) have been demonstrated in several studies, whether H2S protects against early brain injury (EBI) and secondary cognitive dysfunction in subarachnoid hemorrhage (SAH) model remain unknown. The present study was undertaken to evaluate the influence of H2S on both acute brain injury and neurobehavioral changes as well as the underlying mechanisms after SAH. The H2S donor, NaHS, ...περισσότερα »
Arteriolar calcification, and idiopathic basal ganglia calcification
SLC20A2 deficiency in mice leads to elevated phosphate levels in cerbrospinal fluid and glymphatic pathway-associated arteriolar calcification, and recapitulates human idiopathic basal ganglia calcification: Abstract Idiopathic basal ganglia calcification is a brain calcification disorder that has been genetically linked to autosomal dominant mutations in the sodium-dependent phosphate co-transporter, SLC20A2. The mechanisms whereby deficiency of Slc20a2 leads to basal ganglion calcification are unknown. In the mouse brain, we found that *Slc20a2* was expressed in tissues that pro...περισσότερα »
Unilateral hypoplasia with contralateral hypertrophy of anterior belly of digastric muscle: a case report
Unilateral hypoplasia with contralateral hypertrophy of anterior belly of digastric muscle: a case report: AbstractAnomalies of the anterior belly of the digastric muscle (DM) are uncommon. We present a case of hypoplasia of the anterior belly of the left DM with hypertrophy of the anterior belly of the contralateral DM. The importance of recognizing this finding is to differentiate hypoplasia of the anterior belly of the DM from denervation atrophy, and not to confuse contralateral hypertrophy with a submental mass or lymphadenopathy. In denervation atrophy of the anterior belly o... περισσότερα »
Chronic watery diarrhea, weight loss, and frequent sinus and nail fungal infections
A 73-year-old woman with persistent diarrhea and onychomycosis: Abstract:We present a case of a 73-year-old woman who presented with chronic watery diarrhea, weight loss, and frequent sinus and nail fungal infections. Her previous workup with a gastroenterologist failed to reveal any causative agent for her symptoms. She considered herself healthy until a thymic tumor was discovered and removed years ago. Subsequently, she developed multiple sinus infections refractory to treatment. Relevant immunology laboratory tests were conducted, which led to the diagnosis. This case illustr...περισσότερα »
Carbapenem-resistant and colistin-resistant Escherichia coli co-producing NDM-9 and MCR-1
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 7 δευτερόλεπτα
Publication date: Available online 1 February 2016 Source:The Lancet Infectious Diseases Author(s): Xu Yao, Yohei Doi, Li Zeng, Luchao Lv, Jian-Hua Liu from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1WX5szN via IFTTT
Emergence of the mcr-1 colistin resistance gene in carbapenem-resistant Enterobacteriaceae
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 7 δευτερόλεπτα
Publication date: Available online 1 February 2016 Source:The Lancet Infectious Diseases Author(s): Hong Du, Liang Chen, Yi-Wei Tang, Barry N Kreiswirth from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1WX5sjt via IFTTT
Carbapenem-resistant and colistin-resistant Escherichia coli co-producing NDM-9 and MCR-1
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 7 δευτερόλεπτα
Publication date: Available online 1 February 2016 Source:The Lancet Infectious Diseases Author(s): Xu Yao, Yohei Doi, Li Zeng, Luchao Lv, Jian-Hua Liu from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1WX5szN via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
Emergence of the mcr-1 colistin resistance gene in carbapenem-resistant Enterobacteriaceae
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 7 δευτερόλεπτα
Publication date: Available online 1 February 2016 Source:The Lancet Infectious Diseases Author(s): Hong Du, Liang Chen, Yi-Wei Tang, Barry N Kreiswirth from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1WX5sjt via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
Neuroprotective Activity of Curcumin in Combination with Piperine against Quinolinic Acid Induced Neurodegeneration in Rats
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 7 δευτερόλεπτα
Aim: Quinolinic acid (QA) is an excitotoxin that induces Huntington’s-like symptoms in animals and humans. Curcumin (CMN) is a well-known antioxidant but the major problem is its bioavailability. Therefore, the present study was designed to investigate the effect of CMN in the presence of piperine against QA-induced excitotoxic cell death in rats. Material and Methods: […]
Neuroprotective Activity of Curcumin in Combination with Piperine against Quinolinic Acid Induced Neurodegeneration in Rats
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 7 δευτερόλεπτα
Aim: Quinolinic acid (QA) is an excitotoxin that induces Huntington’s-like symptoms in animals and humans. Curcumin (CMN) is a well-known antioxidant but the major problem is its bioavailability. Therefore, the present study was designed to investigate the effect of CMN in the presence of piperine against QA-induced excitotoxic cell death in rats. Material and Methods: […]
Negotiating knowledge: parents’ experience of the neuropsychiatric diagnostic process for children with autism
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 7 δευτερόλεπτα
Abstract Background Parents often recognize problems in their child’s development earlier than health professionals do and there is new emphasis on the importance of involving parents in the diagnostic process. In Gothenburg, Sweden, over 100 children were identified as having an autism spectrum disorder (ASD) in 2009–11 through a general population language and autism screening […]
Negotiating knowledge: parents’ experience of the neuropsychiatric diagnostic process for children with autism
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 7 δευτερόλεπτα
Abstract Background Parents often recognize problems in their child’s development earlier than health professionals do and there is new emphasis on the importance of involving parents in the diagnostic process. In Gothenburg, Sweden, over 100 children were identified as having an autism spectrum disorder (ASD) in 2009–11 through a general population language and autism screening […]
Proton therapy as effective as conventional radiotherapy, with fewer side effects
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 7 δευτερόλεπτα
A trial finds a type of radiotherapy that uses protons instead of photons or X-rays is as effective at treating medulloblastoma in children and causes fewer long-term side effects. from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1PLDNfv via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
Proton therapy as effective as conventional radiotherapy, with fewer side effects
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 7 δευτερόλεπτα
A trial finds a type of radiotherapy that uses protons instead of photons or X-rays is as effective at treating medulloblastoma in children and causes fewer long-term side effects. from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1PLDNfv via IFTTT
TRPV6 plays a new role in predicting survival of patients with esophageal squamous cell carcinoma
Alexandros G. SfakianakisστοHead,Neck,Brain,Cervical Spine and Esophageal Cancers by Alexandros G. SfakianakisΠριν από 8 δευτερόλεπτα
TRPV6 plays a new role in predicting survival of patients with esophageal squamous cell carcinoma: TRPV6 is over-expressed and promotes the proliferation and invasion in many cancers. The association between the expression of TRPV6 and clinical outcome in esophageal squamous cell carcinoma (ESCC) has not be...
Clonality analysis of multifocal papillary thyroid carcinoma by using genetic profiles
Alexandros G. SfakianakisστοHead,Neck,Brain,Cervical Spine and Esophageal Cancers by Alexandros G. SfakianakisΠριν από 11 δευτερόλεπτα
Clonality analysis of multifocal papillary thyroid carcinoma by using genetic profiles: Abstract Papillary thyroid carcinoma (PTC) is the most common adult thyroid malignancy and often presents with multiple anatomically distinct foci within the thyroid, known as multifocal papillary thyroid carcinoma (MPTC). The widespread application of the next-generation sequencing technologies in cancer genomics research provides novel insights into determining the clonal relationship between multiple tumours within the same thyroid gland. For eight MPTC patients, we performed whole-exome sequ...περισσότερα »
Difficulties encountered in the emergency department by patients with hereditary angioedema experiencing acute attacks
Difficulties encountered in the emergency department by patients with hereditary angioedema experiencing acute attacks: Abstract:Background: Hereditary angioedema (HAE) is a rare, potentially life-threatening disease characterized by recurrent angioedema attacks. Abdominal symptoms of HAE typically mimic numerous abdominal emergencies, which may result in a delay of correct diagnosis and inappropriate treatments. Objective: We aimed to evaluate the difficulties experienced by patients with HAE in Turkish emergency departments (ED). Methods: We conducted face-to-face inter... περισσότερα »
Lifetime prevalence of childhood eczema and the effect of indoor environmental factors: Analysis in Hispanic and non-Hispanic white children
*Lifetime prevalence of childhood eczema and the effect of indoor environmental factors: Analysis in Hispanic and non-Hispanic white children: * Abstract: *Background: The prevalence of eczema varies markedly across the globe. It is unclear whether the geographic variation is due to race and/or ethnic differences, environmental exposures, or genetic factors. Objective: We investigated the effects of ethnicity and environmental exposures on eczema in Hispanic white and non-Hispanic white children who participated in the Southern California Children's Health Study. ... περισσότερα »
The value of the clinical history for the diagnosis of immediate nonsteroidal anti-inflammatory drug hypersensitivity and safe alternative drugs in children
*The value of the clinical history for the diagnosis of immediate nonsteroidal anti-inflammatory drug hypersensitivity and safe alternative drugs in children: * Abstract: *Background: Diagnosing hypersensitivity reactions that develop as a result of nonsteroidal anti-inflammatory drugs (NSAID) with a history is mostly misleading, and skin tests and/or provocation tests are needed for a definitive diagnosis. Objective: To determine the frequency of actual NSAID hypersensitivity and whether there are any parameters in the history to predict NSAID hypersensitivity. I... περισσότερα »
Dosing of European sublingual immunotherapy maintenance solutions relative to monthly recommended dosing of subcutaneous immunotherapy
Dosing of European sublingual immunotherapy maintenance solutions relative to monthly recommended dosing of subcutaneous immunotherapy: Abstract:Background: Recently, a series of assays has been conducted in which sublingual immunotherapy (SLIT) maintenance extracts of European manufacturers were compared with U.S. concentrated extracts by using U.S. Food and Drug Administration recommended *in vitro* testing. These test results have been published. We herein performed further data analysis to facilitate interpretation of SLIT dosing by U.S. physicians. Objective: To express...περισσότερα »
Birch allergy and oral allergy syndrome: The practical relevance of serum immunoglobulin E to Bet v 1
Birch allergy and oral allergy syndrome: The practical relevance of serum immunoglobulin E to Bet v 1: Abstract:Background: Birch allergy (BA) may frequently be associated with fruit-vegetables oral allergy syndrome (OAS). Bet v 1 is the major birch allergen. Previously, it was reported that serum-specific immunoglobulin E (IgE) level could differentiate allergy from sensitization. Thus, this study aimed to investigate the practical role of Bet v 1 IgE. Methods: A total of 245 subjects (128 women, 117 men; mean age, 41 years) with suspected allergic rhinitis and sensitizatio...περισσότερα »
Biomarker assessment in chronic rhinitis and chronic rhinosinusitis: Endothelin-1, TARC/CCL17, neopterin, and α-defensins
Biomarker assessment in chronic rhinitis and chronic rhinosinusitis: Endothelin-1, TARC/CCL17, neopterin, and α-defensins: Abstract:Background: Chronic rhinitis (CR) is characteristically divided into several major clinical phenotypes: allergic rhinitis (AR); nonallergic, noninfectious rhinopathy (NAR); and chronic rhinosinusitis (CRS). CRS has two phenotypic variants: CRS with nasal polyps (CRSwNP) and CRS without nasal polyps (CRSsNP). An area of growing interest is to identify biologic markers that could assess different aspects of CR phenotypes. Objective: The aim of the... περισσότερα »
Differential effect of omalizumab on pulmonary function in patients with allergic asthma with and without chronic rhinosinusitis
Differential effect of omalizumab on pulmonary function in patients with allergic asthma with and without chronic rhinosinusitis: Abstract:Background: Omalizumab, an anti-immunoglobulin E monoclonal antibody, is approved by the U.S. Food and Drug Administration for the management of patients with allergic asthma and with refractory disease, and has also proven beneficial in the management of selected patients with chronic rhinosinusitis (CRS). The common airway model indicates that patients with both allergic asthma and CRS may be more challenging to manage clinically. This is t...περισσότερα »
Association between urticaria and virus infections
Association between urticaria and virus infections: A systematic review: Abstract:Background: The association between urticaria and virus infections has rarely been reported in the literature. The lack of reported cases is probably due to the difficulty in establishing a cause-and-effect relationship. It is not possible to challenge the patient with an etiologic agent. Objective: The purpose of this work was to perform a systematic review on the association between urticaria and virus infections. Methods: This systematic review was conducted according to Preferred Reportin... περισσότερα »
Adrenal suppression by inhaled corticosteroids
Adrenal suppression by inhaled corticosteroids in patients with asthma: A systematic review and quantitative analysis: Abstract:Background: Inhaled corticosteroids used for treating persistent asthma can suppress adrenal cortisol secretion. This inhibition of endogenous cortisol secretion is an important marker of systemic steroid activity. Although meta-analyses have demonstrated a dose-dependent suppression of cortisol by inhaled corticosteroids, regardless of inhaler type, the impact of novel freon-free inhaled corticosteroid preparations has not been reviewed. Objective: ... περισσότερα »
Antioxidant supplementation and exhaled nitric oxide in children with asthma
Antioxidant supplementation and exhaled nitric oxide in children with asthma: Abstract:Background: The effect of allergen avoidance on airway inflammation is similar to that observed with treatment with inhaled steroids, whereas inhaled steroids have no effect on oxidative stress‐induced inflammation. Objective: The aim of this study was to retrospectively evaluate the potential effect of an antioxidant dietary supplement on exhaled nitric oxide over a month in pediatric patients on stable antiasthma treatment. Methods: Forty-seven children with moderate-to-severe asthma ... περισσότερα »
Examining causes of the urban (inner city) asthma epidemic: Implementing new management strategies
Examining causes of the urban (inner city) asthma epidemic: Implementing new management strategies: Abstract:Asthma in the inner city contributes to high morbidity and mortality, and, in school children, reduced school attendance and alteration in academic performance. There is a need to improve asthma care in the inner city by reducing asthma exacerbations. Methods are currently available to predict and prevent seasonal exacerbations of asthma. In addition, new medications are being developed that will be effective in improving pulmonary function and reducing asthma exacerbation...περισσότερα »
Exploiting IL-17-producing CD4 + and CD8 + T cells to improve cancer immunotherapy in the clinic
Exploiting IL-17-producing CD4 + and CD8 + T cells to improve cancer immunotherapy in the clinic: AbstractCancer immunotherapy is one the most effective approaches for treating patients with tumors, as it bolsters the generation and persistence of memory T cells. In preclinical work, it has been reported that adoptively transferred CD4+ and CD8+ lymphocytes that secrete IL-17A (i.e., Th17 and Tc17 cells) regress tumors to a greater extent than IFN-γ+Th1 or Tc1 cells in vivo. Herein, we review the mechanisms underlying how infused Th17 and Tc17 cells regress established malignancies...περισσότερα »
Association of carbon monoxide levels with allergic diseases in children
Association of carbon monoxide levels with allergic diseases in children Abstract:Background: Air pollution is regarded as a potential reason for the development or aggravation of allergic diseases. Objective: To investigate the relationship between exposure to outdoor air pollution during the first year of life and the development of allergic diseases, and to determine the association between outdoor air pollution near the residence and recent symptoms of allergic diseases in children. Methods: A nationwide cross-sectional survey was conducted in 6- to 7-year-old children... περισσότερα »
Orphan immunotherapies for allergic diseases
Orphan immunotherapies for allergic diseases: As confirmed by systematic reviews and meta-analyses, allergen immunotherapy is clinically effective in the treatment of allergic diseases. In particular, subcutaneous immunotherapy is a pivotal treatment in patients with severe reactions to Hymenoptera venom, whereas subcutaneous immunotherapy and sublingual immunotherapy are indicated in the treatment of allergic rhinitis and asthma by inhalant allergens. Other allergies related to animal dander (other than cat, which is the most studied), such as dog, molds, occupational allergens, an...περισσότερα »
Exploring racial differences in IgE-mediated food allergy in the WHEALS birth cohort
Exploring racial differences in IgE-mediated food allergy in the WHEALS birth cohort: Suspected food allergies are the cause of more than 200,000 visits to the emergency department annually. Racial differences in the prevalence of food allergy have also been reported, but the evidence is less conclusive. Researchers continue to struggle with the identification of food allergy for epidemiologic studies.
The keratin 13 gene in oral squamous cell carcinoma cells
Mechanistic insight into the aberrant silencing of via ScienceDirect Publication: Journal of Oral Biosciences Publication date: Available online 29 January 2016 *Source:*Journal of Oral Biosciences Author(s): Mitsutoki Hatta, Seiichi Arita, Jun Yamazaki BackgroundEpigenetic regulation is essential for the modulation of cell- and tissue-specific gene expression. In cancer cells, disruption of the normal patterns of chromatin modifications results in aberrant gene expression, which leads to the acquisition of aggressive phenotypes. Oral squamous cell carcinoma (OSCC) is the most common n... περισσότερα »
Thoracic radionecrosis management
Change of paradigm in thoracic radionecrosis management via Plastique Esthétique Publication date: Available online 29 January 2016 *Source:*Annales de Chirurgie Plastique Esthétique Author(s): S. Dast, N. Assaf, L. Dessena, H. Almousawi, C. Herlin, P. Berna, R. Sinna Classically, muscular or omental flaps are the gold standard in the management of thoracic defects following radionecrosis debridement. Their vascular supply and antibacterial property was supposed to enhance healing compared with cutaneous flaps. The evolution of reconstructive surgery allowed us to challenge this dogma....περισσότερα »
Bacterial composition in whole saliva from patients with severe hyposalivation– a case-control study
Bacterial composition in whole saliva from patients with severe hyposalivation– a case-control study: Abstract Objective The purpose of this study was to compare the microbiota of stimulated whole saliva samples from patients with severe hyposalivation to samples from individuals with normal whole saliva flow rates. It was hypothesized that the two groups differ with regard to salivary bacterial profiles. Methods This cross-sectional study included 36 participants (24 females and 12 males, mean age 58.5 years) with severe hyposalivation and 36 gender-, age- and geographically-matche... περισσότερα »
Mandibular Condyle Reimplantation and Free Bone Grafting
Mandibular Condyle Reimplantation and Free Bone Grafting: Considerations to Increase Its Efficacy.: Background: Mandibulectomy and disarticulation, resection of the lesion, and subsequent reimplantation of the condyle is a method to manage benign mandibular intraosseous lesions, involving the ramus but not extending to the mandibular condyle. Objective: This article presents some considerations to increase the efficacy of this method. Method and Material: Archived files of the patients that this method had been used for mandibular reconstruction were reevaluated. Patients were recall...περισσότερα »
Entrapment of soft tissue: a new technique to improve the stability of malar augmentation with hydroxyapatite
Entrapment of soft tissue: a new technique to improve the stability of malar augmentation with hydroxyapatite: As far as we know the first reports of the use of hydroxyapatite for malar augmentation were published in 1986.1 Its use in the form of granules has since been shown to produce a more predictable result with fewer complications than implant blocks.2 The granules also permit moulding after implantation, so that the material becomes compacted and approximates closely to the surface of the bone. Moulding is possible because the hydroxyapatite is packed under the periosteum and... περισσότερα »
Treatment Efficacy of the Transsylvian Approach Versus the Transtemporal Cortex Approach to Evacuate Basal Ganglia Hematoma Under a Microscope.
Treatment Efficacy of the Transsylvian Approach Versus the Transtemporal Cortex Approach to Evacuate Basal Ganglia Hematoma Under a Microscope.: This study aimed to evaluate the clinical efficacy of the transsylvian approach versus the transtemporal cortex approach to evacuate basal ganglia hemorrhage under a microscope. The relevant literature was collected from PubMed, Embase, Cochrane Central Register of Controlled Trials, Chinese Biomedical Literature database, and China National Knowledge Infrastructure databases. The meta-analysis was conducted by Stata 12.0 software. Seven st... περισσότερα »
Scalp Dermatofibrosarcoma Protuberans: A Potential Diagnostic Pitfall.
Scalp Dermatofibrosarcoma Protuberans: A Potential Diagnostic Pitfall
Acellular Dermal Graft in Secondary Cleft Lip Deficiencies: Assessment of Results With a Reproducible Quantitative Technique.
Acellular Dermal Graft in Secondary Cleft Lip Deficiencies: Assessment of Results With a Reproducible Quantitative Technique.: Purpose: Considering the little evidence around acellular dermal graft application in secondary lip reshaping, this study is aimed to quantitatively examine the effect of acellular dermal graft in combination with Z-plasty technique in secondary defects of cleft lip. Methods: In this clinical investigation, patients with secondary unilateral cleft lip deformity were selected. Standard photographs were prepared for each patient. Subsequent to scar revision, su... περισσότερα »
Alveolar Bone, Upper Lip and Columellar Reconstruction With Composite Abbe Flap.
Alveolar Bone, Upper Lip and Columellar Reconstruction With Composite Abbe Flap.: Bilateral cleft lip and palate repair usually requires secondary corrective intentions. Abbe flap is a useful option and has many modifications for revision surgeries of cleft lip nose deformities. Study evaluated a 23-year-old woman for secondary cleft lip nose correction. The authors performed a composite Abbe flap, which included mental bone for repairing the upper lip harmony, maintaining the columellar elongation and bridging central alveolar bone cleft. No complications were observed and aestheti... περισσότερα »
Assessment of Patient Satisfaction With Evaluation Methods in Open Technique Septorhinoplasty.
Assessment of Patient Satisfaction With Evaluation Methods in Open Technique Septorhinoplasty.: The aim of this study was to measure the postoperative satisfaction of patients who underwent open technique septorhinoplasty (SRP) using Nasal Obstruction Symptoms Evaluation (NOSE), Rhinoplasty Outcomes Evaluation (ROE) and visual analog scale (VAS), and to assess the reliability and usability of these forms in the outcome of SRP. Forty-five patients who underwent primary open technique SRP were included in the study. The levels of patient satisfaction were assessed before the surgery an...περισσότερα »
Forehead Mass Removal by Endoscopic Approach.
Forehead Mass Removal by Endoscopic Approach.: Patients with forehead mass have a cosmetic problem because the forehead is an important first impression. Conventional skin approach results in visible scar even though surgeons designed the incision along the relaxed skin tension line1. Since Onishi introduced the technique for endoscopic approach in 1995, endoscopic surgery has become rapidly popular in the field of plastic surgery. Endoscopic approach to the forehead mass by small incision on the scalp behind hair line is big advantageous for leaving less ugly scar on the forehead. ...περισσότερα »
Comparison of Nasal Septum and Ear Cartilage as a Graft for Lower Eyelid Reconstruction.
Comparison of Nasal Septum and Ear Cartilage as a Graft for Lower Eyelid Reconstruction.: In lower eyelid reconstruction, several types of grafts from the nasal septum, ear cartilage, buccal mucosa, and hard palate mucosa have been used for an inner layer of the lower eyelid, but there have been no studies comparing these grafts. The authors retrospectively reviewed our cases of lower eyelid reconstruction, and compared chondromucosal grafts from the nasal septum (N = 8) and ear cartilage grafts (N = 10) for an inner layer of the lower eyelid. The authors observed no significant dif... περισσότερα »
Cleft Le Fort I Osteotomy: A Video Presentation.
Cleft Le Fort I Osteotomy: A Video Presentation.: In this video, we present a single piece Le Fort I osteotomy with bone graft in a patient with a unilateral cleft lip and palate. Maxillary osteotomies in the cleft patient can be challenging because of the presence of scar, palatal or alveolar fistulae, compromised teeth, and vascularization of the segments. The video demonstrates our current approach and technique. The authors particularly want to highlight aspects of the approach, such as the incision, exposure, osteotomies, mobilization, splints, and plating. The associated manusc... περισσότερα »
Prevention of Recurrence in the Surgical Correction of Cryptotia Using Local Flaps With a Cartilage Wedge Graft.
Prevention of Recurrence in the Surgical Correction of Cryptotia Using Local Flaps With a Cartilage Wedge Graft.: Cryptotia attributable to deficient posterior skin coverage frequently recurs. Because local flaps cover only the posterior aspects of the defective upper auricular cartilage and lack functional support to resist collapse of the helix, especially if severe helical cartilage anomalies are present, additional support is required to prevent the postoperative recurrence of this anomaly. The authors present cases of cryptotia treated using local flaps including a Z-plasty or ... περισσότερα »
The Management of Nonsyndromic, Isolated Sagittal Synostosis.
The Management of Nonsyndromic, Isolated Sagittal Synostosis.: Aim: Isolated sagittal synostosis is the commonest form of craniosynostosis. The reasons for surgery are to normalize the head shape and to increase the cranial volume, thus reducing the risk of raised intracranial pressure and allowing for normal brain development. It has been suggested that sagittal synostosis may impair neuropsychological development. This systematic review appraised the literature on the management of sagittal synostosis. Methods: A literature search was performed with the assistance of a professional...περισσότερα »
Stimulation of Nitric Oxide Production Contributes to the Antithrombotic Effect of Stromal Cell–Derived Factor-1α in Preventing Microsurgical Anastomotic Thrombosis
Stimulation of Nitric Oxide Production Contributes to the Antithrombotic Effect of Stromal Cell–Derived Factor-1α in Preventing Microsurgical Anastomotic Thrombosis: J reconstr Microsurg DOI: 10.1055/s-0036-1571797 Background Intimal injury plays a critical role in initiating the pathogenesis of thrombosis formation after microsurgical anastomosis. Application of stromal cell–derived factor-1α (SDF-1α) is reported to promote early regeneration of injured intima through migration of endothelial cells and mobilization of endothelial progenitor cells. We therefore hypothesized that l... περισσότερα »
The skin depigmenting potential of Paeonia lactiflora root extract and Paeoniflorin
The skin depigmenting potential of Paeonia lactiflora root extract and Paeoniflorin: in vitro evaluation using reconstructed pigmented human epidermis: Abstract Objective The roots of the herb Paeonia lactiflora (“White Peony”) are used in association with other herbs in traditional clinical cosmetic practice in China as oral treatment for skin pigmentary disorders, such as brown or dark pigmentary spots. However, the skin depigmenting potential of Paeonia lactiflora root extract and its main ingredient paeoniflorin has been scarcely investigated by topical application. The purpose... περισσότερα »
The regenerative role of adipose-derived stem cells (ADSC) in plastic and reconstructive surgery
The regenerative role of adipose-derived stem cells (ADSC) in plastic and reconstructive surgery: Abstract The potential use of stem cell-based therapies for the repair and regeneration of various tissues and organs offers a paradigm shift in plastic and reconstructive surgery. The use of either embryonic stem cells (ESC) or induced pluripotent stem cells (iPSC) in clinical situations is limited because of regulations and ethical considerations even though these cells are theoretically highly beneficial. Adult mesenchymal stem cells appear to be an ideal stem cell population for pr... περισσότερα »
Cell Renewal,Anti-Aging,Whitening,and Anti-Cellulite properties : Evaluation of the enzymatic activity and stability of commercial bromelain incorporated in topical formulations
Evaluation of the enzymatic activity and stability of commercial bromelain incorporated in topical formulations: Abstract Bromelain is a mixture of proteolytic enzymes found in various tissues of the pineapple plant (*Ananas comosus*) and other species of *Bromeliaceae*. Owing to its proteolytic activity, bromelain has been used in the food, medical, pharmaceutical, and cosmetic industries, for its cell renewal, anti-aging, whitening, and anti-cellulite properties Objective This study evaluated the stability of bromelain (commercial powder) incorporated in topical formulations Metho... περισσότερα »
Impact of chemical peeling combined with negative pressure on human skin
Impact of chemical peeling combined with negative pressure on human skin: Abstract Objective In vivo changes in skin barrier function after chemical peeling with alpha hydroxyacids (AHAs) have been previously reported. However, the additional effects of physical treatment with chemical agents on skin barrier function have not been adequately studied. This study measured the degree of acute skin damage and the time required for skin barrier repair using noninvasive bioengineering methods in vivo with human skin to investigate the additional effect of a 4% AHA chemical jet accelerated...περισσότερα »
Fluid leakage across endotracheal tube cuffs
Comparison of fluid leakage across endotracheal tube cuffs using a three-dimensional printed model of the human trachea: Abstract The objective of this study was to compare fluid leakage across endotracheal tube cuffs using a three-dimensional (3D)-printed human tracheal model that anatomically simulates the human trachea. We made two models based on computed tomography data of the neck and chest. Using a Mallinckrodt Hi-Lo™ (HL), ThinCuff® (TC), and Mallinckrodt TaperGuard™ (TG), we sequentially measured the amount of fluid leakage across each endotracheal tube cuff after applying... περισσότερα »
Difficult airway management using the Pentax-AWS Airwayscope with a thin Intlock and bronchofiberscope in a patient with Coffin-Lowry syndrome
Difficult airway management using the Pentax-AWS Airwayscope with a thin Intlock and bronchofiberscope in a patient with Coffin-Lowry syndrome: We report a case of difficult tracheal intubation in which the use of a bronchofiberscope (BFS) with the Pentax-AWS Airwayscope (AWS; HOYA, Japan) having a thin Intlock (ITL-TL, HOYA, Japan) proved useful in a patient with Coffin-Lowry syndrome.
Accidental arterial local anesthetic injection under ultrasound-guided stellate ganglion block
A rare case of accidental arterial local anesthetic injection under ultrasound-guided stellate ganglion block: Intraarterial injection of local anesthetic during stellate ganglion block (SGB) can cause life-threatening complications. Here we report a rare case of accidental arterial local anesthetic injection under ultrasound-guided (USG) SGB.
Smartphone camera system to enable visualization and image transmission to aid tracheal intubation with the Airtraq ® laryngoscope
Evaluation of a smartphone camera system to enable visualization and image transmission to aid tracheal intubation with the Airtraq ® laryngoscope: AbstractUsing three-dimensional printing, we produced adaptors to attach a smartphone with camera to the eyepiece of the Airtraq® laryngoscope. This low-cost system enabled a team to simultaneously view the laryngoscopy process on the smartphone screen, and also enabled image transmission. We compared the Airtraq® with the smartphone Airtraq® system in a crossover study of trainee anesthesiologists performing tracheal intubation in a ma...περισσότερα »
Central venous pressure: soon an outcome-associated matter.
Central venous pressure: soon an outcome-associated matter.: Purpose of review: Central venous pressure (CVP) alone has so far not found a place in outcome prediction or prediction of fluid responsiveness. Improved understanding of the interaction between mean systemic pressure (Pms) and CVP has major implications for evaluating volume responsiveness, heart performance and potentially patient outcomes. Recent findings: The literature review substantiates that CVP plays a decisive role in causation of operative haemorrhage and renal failure. The review details CVP as a variable integr...περισσότερα »
Impact of chemical peeling combined with negative pressure on human skin
Abstract Objective In vivo changes in skin barrier function after chemical peeling with alpha hydroxyacids (AHAs) have been previously reported. However, the additional effects of physical treatment with chemical agents on skin barrier function have not been adequately studied. This study measured the degree of acute skin damage and the time required for skin barrier repair using noninvasive bioengineering methods in vivo with human skin to investigate the additional effect of a 4% AHA chemical jet accelerated at supersonic velocities. Methods Thirteen female subjects (average age:... περισσότερα »
Evaluation of the enzymatic activity and stability of commercial bromelain incorporated in topical formulations
Abstract Bromelain is a mixture of proteolytic enzymes found in various tissues of the pineapple plant (*Ananas comosus*) and other species of *Bromeliaceae*. Owing to its proteolytic activity, bromelain has been used in the food, medical, pharmaceutical, and cosmetic industries, for its cell renewal, anti-aging, whitening, and anti-cellulite properties Objective This study evaluated the stability of bromelain (commercial powder) incorporated in topical formulations Methods Bromelain was incorporated at three concentrations, 0.5%, 1.0%, and 2.0%, in oil-in-water emulsion and gel, a... περισσότερα »
Insufficient disease inhibition by intrathecal rituximab in progressive multiple sclerosis
Abstract Objective Inaccessibility of the inflammation compartmentalized to the central nervous system (CNS) may underlie the lack of efficacy of immunomodulatory treatments in progressive multiple sclerosis (MS). The double blind combination of Rituximab by IntraVenous and IntraThecAl injection versus placebo in patients with Low-Inflammatory SEcondary progressive MS (RIVITALISE; NCT01212094) trial was designed to answer: (1) Whether an induction dose of intravenous and intrathecal rituximab efficiently depletes CNS B cells? and (2) If so, whether this leads to global inhibition o... περισσότερα »
Plasma neurofilament light chain predicts progression in progressive supranuclear palsy
Abstract Objective Blood-based biomarkers for neurodegenerative conditions could improve diagnosis and treatment development. Neurofilament light chain (NfL), a marker of axonal injury, is elevated in cerebrospinal fluid (CSF) of patients with progressive supranuclear palsy (PSP). The goal of this study was to determine the diagnostic and prognostic value of plasma NfL in patients with PSP. Methods Plasma NfL was measured with ultrasensitive digital immunoassay-based technology at baseline and 1-year follow-up in a pilot cohort of 15 PSP patients and 12 healthy controls, and a vali...περισσότερα »
Parkinson disease and progressive supranuclear palsy: protein expression in skin
Abstract Objective This study characterizes the expression of tau (p-tau) and *α*-synuclein ( *α*-syn) by immunohistochemistry in the skin of three different populations: healthy control (HC), Parkinson disease (PD), and progressive supranuclear paralysis (PSP) subjects, with the purpose of finding a biomarker that could differentiate between subjects with PD and PSP. Material and Methods We evaluated the presence of p-tau and *α*-syn in a pilot study in the skin of three distinct groups of patients: 17 healthy subjects, 17 patients with PD, and 10 patients with PSP. Four millimeters... περισσότερα »
Impact of chemical peeling combined with negative pressure on human skin
Abstract Objective In vivo changes in skin barrier function after chemical peeling with alpha hydroxyacids (AHAs) have been previously reported. However, the additional effects of physical treatment with chemical agents on skin barrier function have not been adequately studied. This study measured the degree of acute skin damage and the time required for skin barrier repair using noninvasive bioengineering methods in vivo with human skin to investigate the additional effect of a 4% AHA chemical jet accelerated at supersonic velocities. Methods Thirteen female subjects (average a... περισσότερα »
Evaluation of the enzymatic activity and stability of commercial bromelain incorporated in topical formulations
Abstract Bromelain is a mixture of proteolytic enzymes found in various tissues of the pineapple plant (*Ananas comosus*) and other species of *Bromeliaceae*. Owing to its proteolytic activity, bromelain has been used in the food, medical, pharmaceutical, and cosmetic industries, for its cell renewal, anti-aging, whitening, and anti-cellulite properties Objective This study evaluated the stability of bromelain (commercial powder) incorporated in topical formulations Methods Bromelain was incorporated at three concentrations, 0.5%, 1.0%, and 2.0%, in oil-in-water emulsion and gel... περισσότερα »
An approach to using central pupils as a clinical sign to assess depth of anesthesia in infants undergoing fundus examination with inhalation of sevoflurane
An approach to using central pupils as a clinical sign to assess depth of anesthesia in infants undergoing fundus examination with inhalation of sevoflurane: [image: gr1.sml] To determine whether depth of anesthesia correlates with central pupils in outpatient infants undergoing fundus examination during general anesthesia.
Effect of laryngotracheal topical anesthesia on recurrent laryngeal nerve monitoring during thyroid Surgery
Effect of laryngotracheal topical anesthesia on recurrent laryngeal nerve monitoring during thyroid Surgery: [image: gr1.sml] Intraoperative neuromonitoring of the recurrent laryngeal nerve (RLN) is often used as an adjunct for RLN identification and preservation during thyroidectomies. Laryngotracheal anesthesia (LTA) with topical lidocaine reduces coughing upon emergence from anesthesia and in the immediate postoperative period; however, its use is prohibited with concerns that it could decrease the sensitivity of the intraoperative neuromonitoring. We hypothesize that there ... περισσότερα »
Systematic review with network meta-analysis: comparative effectiveness of topical steroids vs. PPIs for the treatment of the spectrum of eosinophilic oesophagitis
Summary Background Controversy surrounds the clinical and histological response to topical steroids in patients with eosinophilic oesophagitis (EoE). Aim To perform a systematic review and network meta-analysis of randomised controlled trials to assess the efficacy of topical steroids compared with placebo or proton pump inhibitor (PPIs) for the management of eosinophilic oesophagitis. Methods Cochrane Central Register of Controlled Trials and MEDLINE from inception to 1 July 2015 was searched. Data were extracted independently by two authors. Methodological quality was assesse... περισσότερα »
Editorial Board
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 41 δευτερόλεπτα
Publication date: March 2016 Source:Basal Ganglia, Volume 6, Issue 1 from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1QSMQ3s via IFTTT
Comment Zika virus outbreak in the Americas: the need for novel mosquito control methods
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 41 δευτερόλεπτα
Local transmission of Zika virus (ZIKV) in the Americas was first confirmed in February, 2014, on Easter Island. In May, 2015, 16 patients from the Brazilian states of Bahia and Rio Grande do Norte were found to be ZIKV-positive. 22 countries and territories have subsequently identified autochthonous transmission within the region (figure). Until recently, ZIKV […]
Editorial Board
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 41 δευτερόλεπτα
Publication date: March 2016 Source:Basal Ganglia, Volume 6, Issue 1 from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1QSMQ3s via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
UK scientists gain licence to edit genes in human embryos
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 41 δευτερόλεπτα
Team at Francis Crick Institute permitted to use CRISPR–Cas9 technology in embryos for early development research. Nature News doi: 10.1038/nature.2016.19270 from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/202rsth via IFTTT
Comment Zika virus outbreak in the Americas: the need for novel mosquito control methods
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 41 δευτερόλεπτα
Local transmission of Zika virus (ZIKV) in the Americas was first confirmed in February, 2014, on Easter Island. In May, 2015, 16 patients from the Brazilian states of Bahia and Rio Grande do Norte were found to be ZIKV-positive. 22 countries and territories have subsequently identified autochthonous transmission within the region (figure). Until recently, ZIKV […]
UK scientists gain licence to edit genes in human embryos
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 41 δευτερόλεπτα
Team at Francis Crick Institute permitted to use CRISPR–Cas9 technology in embryos for early development research. Nature News doi: 10.1038/nature.2016.19270 from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/202rsth via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
Virtual reality makes its best users the most queasy
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 41 δευτερόλεπτα
In a twist of virtual fate, people with the best 3-D vision are also the people most likely to suffer from motion sickness while using virtual reality displays. from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1WX0D9G via IFTTT
Virtual reality makes its best users the most queasy
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 41 δευτερόλεπτα
In a twist of virtual fate, people with the best 3-D vision are also the people most likely to suffer from motion sickness while using virtual reality displays. from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1WX0D9G via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
Combined ab interno trabeculotomy and lens extraction: a novel management option for combined uveitic and chronic narrow angle raised intraocular pressure
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 41 δευτερόλεπτα
Minimally invasive glaucoma surgery is a developing area that has the potential to replace traditional glaucoma surgery, with its known risk profile, but at present there are no randomised controlled data to validate its use. We report on a case where sequential bilateral combined ab interno trabeculotomy and lens extraction surgery was performed on a […]
Cornelia de Lange and Ehlers-Danlos: comorbidity of two rare syndromes
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 41 δευτερόλεπτα
We present a case of a young adult with both Cornelia de Lange syndrome and Ehlers-Danlos syndrome. The patient showed non-verbal autism, intellectual disability and severe/intractable self-harming behaviours that led to a life-threatening complication (ie, septicaemia). A significant reduction in the self-harming behaviours was attained in a multidisciplinary neurobehavioural inpatient unit after addressing all causes […]
Clinical and pathologic features of Aicardi–Goutières syndrome due to an IFIH1 mutation: A pediatric case report
We describe the case of a young patient with calcifying encephalopathy, born to asymptomatic parents. An extensive hypothesis-driven etiological assessment was performed and failed to detect the precise etiology during many years. We therefore decided to perform whole exome sequencing of the child–unaffected parents trio. A *de novo* pathogenic variant in the *IFIH1* gene which has recently been shown to cause autosomal dominant forms of Aicardi–Goutières syndrome was identified. This child presented with a severe form with neonatal thrombocytopenia and hepatomegaly, the latter h...περισσότερα »
Expanding the phenotypic profile of Kleefstra syndrome: A female with low-average intelligence and childhood apraxia of speech
Kleefstra syndrome (KS) is a rare neurogenetic disorder most commonly caused by deletion in the 9q34.3 chromosomal region and is associated with intellectual disabilities, severe speech delay, and motor planning deficits. To our knowledge, this is the first patient (PQ, a 6-year-old female) with a 9q34.3 deletion who has near normal intelligence, and developmental dyspraxia with childhood apraxia of speech (CAS). At 6, the Wechsler Preschool and Primary Intelligence testing (WPPSI-III) revealed a Verbal IQ of 81 and Performance IQ of 79. The Beery Buktenica Test of Visual Motor I... περισσότερα »
Mesenteric lymphangioma mimicking a cystic ovarian mass on imaging
Pelvic cystic masses are frequently observed in women. Most lesions are benign and of ovarian origin. However, non-ovarian lesions can be easily confused with cystic ovarian masses on imaging, which hampers diagnostic and therapeutic management. In this report, a rare case of mesenteric lymphangioma mimicking an ovarian cystic mass, discovered as an incidental finding on orthopaedic MRI in an adult female, is presented. The report highlights the sometimes difficult diagnostic process of pelvic cystic masses, due to an extensive differential diagnosis and the fact that imaging is o...περισσότερα »
Co-occurrence of biphenotypic acute leukaemia, glucose 6-phosphate dehydrogenase deficiency and haemoglobin E trait in a single child
Acute leukaemias occur as the result of clonal expansion subsequent to transformation and arrest at a normal differentiation stage of haematopoietic precursors, which commit to a single lineage, such as myeloid or B-lymphoid or T-lymphoid cells. Biphenotypic acute leukaemia (BAL) constitutes a biologically different group of leukaemia arising from a precursor stem cell and co-expressing more than one lineage specific marker. The present report describes a child with unusual co-occurrence of biphenotypic (B-precursor cell and Myeloid) acute leukaemia, haemoglobin E trait and glucos... περισσότερα »
Lifestyle medicine consulting walking meetings for sustained weight loss
With rates of obesity and diabetes rising worldwide, effective ways of managing weight are becoming more important. We present the case study of a middle-aged Caucasian-American woman (body mass index (BMI) 27.8, overweight category) who wanted to lose weight. The patient participated in a behaviour modification programme with a physician trained in lifestyle medicine as well as health and wellness coaching. After the 14-week programme, which included 9, 1 h long walking sessions with the clinician, the patient lost 11 Ibs (BMI 24.7, normal category). The programme included a comb...περισσότερα »
Two rare cases of appendiceal collision tumours involving an appendiceal mucinous neoplasm and carcinoid
We report two rare cases of appendiceal collision tumours, each involving an appendiceal mucinous neoplasm with a concomitant appendiceal carcinoid. The first case presented with acute appendicitis while the second presented with an incidental radiological finding of an enlarged appendix as part of evaluation for raised serum carcinoembryonic antigen. Diagnosis in both cases was made postoperatively on histological assessment following appendicectomy. Clinical and histological features of both tumour types in each case did not necessitate further surgical resection or adjuvant tre...περισσότερα »
Bilateral and symmetric isolated dorsospinal arteries with prominent anterior radiculomedullary contribution
We present the case of a 15-year-old girl with a left T7 spinal epidural arteriovenous fistula (SEAVF), in whom bilateral and symmetric isolated T9 dorsospinal arteries (DAs) were incidentally documented, each providing a significant contribution to the anterior spinal artery. Recognizing the existence of isolated DAs of direct aortic origin is critical, both for the diagnostic evaluation and for the management of spinal vascular diseases. Notably, isolated DAs tend to branch off significant radiculomedullary arteries, which vascularize the normal spinal cord but have also been sho... περισσότερα »
Insufficient disease inhibition by intrathecal rituximab in progressive multiple sclerosis
Abstract Objective Inaccessibility of the inflammation compartmentalized to the central nervous system (CNS) may underlie the lack of efficacy of immunomodulatory treatments in progressive multiple sclerosis (MS). The double blind combination of Rituximab by IntraVenous and IntraThecAl injection versus placebo in patients with Low-Inflammatory SEcondary progressive MS (RIVITALISE; NCT01212094) trial was designed to answer: (1) Whether an induction dose of intravenous and intrathecal rituximab efficiently depletes CNS B cells? and (2) If so, whether this leads to global inhibition... περισσότερα »
Plasma neurofilament light chain predicts progression in progressive supranuclear palsy
Abstract Objective Blood-based biomarkers for neurodegenerative conditions could improve diagnosis and treatment development. Neurofilament light chain (NfL), a marker of axonal injury, is elevated in cerebrospinal fluid (CSF) of patients with progressive supranuclear palsy (PSP). The goal of this study was to determine the diagnostic and prognostic value of plasma NfL in patients with PSP. Methods Plasma NfL was measured with ultrasensitive digital immunoassay-based technology at baseline and 1-year follow-up in a pilot cohort of 15 PSP patients and 12 healthy controls, and a v...περισσότερα »
Parkinson disease and progressive supranuclear palsy: protein expression in skin
Abstract Objective This study characterizes the expression of tau (p-tau) and *α*-synuclein ( *α*-syn) by immunohistochemistry in the skin of three different populations: healthy control (HC), Parkinson disease (PD), and progressive supranuclear paralysis (PSP) subjects, with the purpose of finding a biomarker that could differentiate between subjects with PD and PSP. Material and Methods We evaluated the presence of p-tau and *α*-syn in a pilot study in the skin of three distinct groups of patients: 17 healthy subjects, 17 patients with PD, and 10 patients with PSP. Four millimet...περισσότερα »
The regenerative role of adipose-derived stem cells (ADSC) in plastic and reconstructive surgery
Abstract The potential use of stem cell-based therapies for the repair and regeneration of various tissues and organs offers a paradigm shift in plastic and reconstructive surgery. The use of either embryonic stem cells (ESC) or induced pluripotent stem cells (iPSC) in clinical situations is limited because of regulations and ethical considerations even though these cells are theoretically highly beneficial. Adult mesenchymal stem cells appear to be an ideal stem cell population for practical regenerative medicine. Among these cells, adipose-derived stem cells (ADSC) have the poten... περισσότερα »
Clinical features and outcomes of delayed facial palsy after head trauma
Publication date: Available online 1 February 2016 *Source:*Auris Nasus Larynx Author(s): Qiang Li, Yanfei Jia, Qian Feng, Bo Tang, Naili Wei, Yinian Zhang, Yefeng Li, Xuanfen Zhang ObjectiveTo investigate clinical features and outcomes of delayed facial palsy after head trauma.MethodsThe cases who had delayed facial palsy after head trauma treated from March 2008 to March 2013 at our hospital were enrolled in the study, and their clinical features and outcomes were analyzed.ResultsThirty-five of 1620 cases developed delayed facial palsy after head trauma. Facial palsy occurred within...περισσότερα »
Macular pigmentation of uncertain aetiology revisited: two case reports and a proposed algorithm for clinical classification
Abstract Ashy dermatosis, erythema dyschromicum perstans, lichen planus pigmentosus and idiopathic eruptive macular pigmentation are various types of acquired macular hyperpigmentation disorders of the skin described in literature. However, a global consensus on the definitions of these entities is lacking. We report two cases of acquired macular (hyper)pigmentation of uncertain aetiology diagnosed as ashy dermatosis and attempt to clarify the various confusing nosologies based on existing literature. We infer that acquired small and large macular pigmentation of uncertain aetiology...περισσότερα »
Single-staged vs. two-staged implant placement using bone ring technique in vertically deficient alveolar ridges – Part 1: histomorphometric and micro-CT analysis
Abstract Background Simultaneous implant placement with bone grafting shortens the overall treatment period, but might lead to the peri-implant bone loss or even implant failure. The aim of this study was to compare the single-staged to two-staged implant placement using the bone ring technique. Material and methods Four standardized alveolar bone defects were made in the mandibles of nine dogs. Dental implants (Straumann BL®, Basel, Switzerland) were inserted simultaneously with bone ring technique in test group and after 6 months of healing period in control group. Animals of both... περισσότερα »
Traumatic Brain Injury and Obesity Induce Persistent Central Insulin Resistance
Abstract Traumatic brain injury (TBI)-induced impairments in cerebral energy metabolism impede tissue repair and contribute to delayed functional recovery. Moreover, the transient alteration in brain glucose utilization corresponds to a period of increased vulnerability to the negative effects of a subsequent TBI. In order to better understand the contributing factors to TBI-induced central metabolic dysfunction, we examined the effect of single and repeated TBIs on brain insulin signaling. Here we show that TBI induces acute brain insulin resistance, which resolves within 7 days f... περισσότερα »
Searching for cognitive enhancement in the Morris watermaze: Better and worse performance in D-amino acid oxidase knockout (Dao-/-) mice
Abstract A common strategy when searching for cognitive enhancing drugs has been to target the NMDA receptor, given its putative role in synaptic plasticity and learning. Evidence in favour of this approach has come primarily from studies with rodents using behavioural assays like the Morris watermaze. D-amino acid oxidase (DAO) degrades neutral D-amino acids such as D-serine, the primary endogenous co-agonist acting at the glycine site of the synaptic NMDA receptor. Inhibiting DAO could therefore provide an effective and viable means of enhancing cognition, particularly in disorder... περισσότερα »
Neurochemical and behavioral indices of exercise reward are independent of exercise controllability
Abstract Brain reward circuits are implicated in stress-related psychiatric disorders. Exercise reduces the incidence of stress-related disorders, but the contribution of exercise reward to stress resistance is unknown. Exercise-induced stress resistance is independent of exercise controllability; both voluntary and forced wheel running protect rats against anxiety- and depression-like behavioral consequences of stress. Voluntary exercise is a natural reward, but whether rats find forced wheel running rewarding is unknown. Moreover, the contribution of dopamine (DA) and striatal re... περισσότερα »
The regenerative role of adipose-derived stem cells (ADSC) in plastic and reconstructive surgery
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 57 δευτερόλεπτα
Abstract The potential use of stem cell-based therapies for the repair and regeneration of various tissues and organs offers a paradigm shift in plastic and reconstructive surgery. The use of either embryonic stem cells (ESC) or induced pluripotent stem cells (iPSC) in clinical situations is limited because of regulations and ethical considerations even though these […]
Clinical features and outcomes of delayed facial palsy after head trauma
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 57 δευτερόλεπτα
Publication date: Available online 1 February 2016 Source:Auris Nasus Larynx Author(s): Qiang Li, Yanfei Jia, Qian Feng, Bo Tang, Naili Wei, Yinian Zhang, Yefeng Li, Xuanfen Zhang ObjectiveTo investigate clinical features and outcomes of delayed facial palsy after head trauma.MethodsThe cases who had delayed facial palsy after head trauma treated from March 2008 to March […]
Searching for cognitive enhancement in the Morris watermaze: Better and worse performance in D-amino acid oxidase knockout (Dao-/-) mice
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 57 δευτερόλεπτα
Abstract A common strategy when searching for cognitive enhancing drugs has been to target the NMDA receptor, given its putative role in synaptic plasticity and learning. Evidence in favour of this approach has come primarily from studies with rodents using behavioural assays like the Morris watermaze. D-amino acid oxidase (DAO) degrades neutral D-amino acids such […]
Virtual reality makes its best users the most queasy
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 57 δευτερόλεπτα
In a twist of virtual fate, people with the best 3-D vision are also the people most likely to suffer from motion sickness while using virtual reality displays. from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1WX0D9G via IFTTT
Macular pigmentation of uncertain aetiology revisited: two case reports and a proposed algorithm for clinical classification
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 57 δευτερόλεπτα
Abstract Ashy dermatosis, erythema dyschromicum perstans, lichen planus pigmentosus and idiopathic eruptive macular pigmentation are various types of acquired macular hyperpigmentation disorders of the skin described in literature. However, a global consensus on the definitions of these entities is lacking. We report two cases of acquired macular (hyper)pigmentation of uncertain aetiology diagnosed as ashy dermatosis […]
Traumatic Brain Injury and Obesity Induce Persistent Central Insulin Resistance
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 57 δευτερόλεπτα
Abstract Traumatic brain injury (TBI)-induced impairments in cerebral energy metabolism impede tissue repair and contribute to delayed functional recovery. Moreover, the transient alteration in brain glucose utilization corresponds to a period of increased vulnerability to the negative effects of a subsequent TBI. In order to better understand the contributing factors to TBI-induced central metabolic dysfunction, […]
Combined ab interno trabeculotomy and lens extraction: a novel management option for combined uveitic and chronic narrow angle raised intraocular pressure
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 57 δευτερόλεπτα
Minimally invasive glaucoma surgery is a developing area that has the potential to replace traditional glaucoma surgery, with its known risk profile, but at present there are no randomised controlled data to validate its use. We report on a case where sequential bilateral combined ab interno trabeculotomy and lens extraction surgery was performed on a […]
Cornelia de Lange and Ehlers-Danlos: comorbidity of two rare syndromes
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 57 δευτερόλεπτα
We present a case of a young adult with both Cornelia de Lange syndrome and Ehlers-Danlos syndrome. The patient showed non-verbal autism, intellectual disability and severe/intractable self-harming behaviours that led to a life-threatening complication (ie, septicaemia). A significant reduction in the self-harming behaviours was attained in a multidisciplinary neurobehavioural inpatient unit after addressing all causes […]
Single-staged vs. two-staged implant placement using bone ring technique in vertically deficient alveolar ridges – Part 1: histomorphometric and micro-CT analysis
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 58 δευτερόλεπτα
Abstract Background Simultaneous implant placement with bone grafting shortens the overall treatment period, but might lead to the peri-implant bone loss or even implant failure. The aim of this study was to compare the single-staged to two-staged implant placement using the bone ring technique. Material and methods Four standardized alveolar bone defects were made in […]
Mesenteric lymphangioma mimicking a cystic ovarian mass on imaging
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 58 δευτερόλεπτα
Pelvic cystic masses are frequently observed in women. Most lesions are benign and of ovarian origin. However, non-ovarian lesions can be easily confused with cystic ovarian masses on imaging, which hampers diagnostic and therapeutic management. In this report, a rare case of mesenteric lymphangioma mimicking an ovarian cystic mass, discovered as an incidental finding on […]
IJMS, Vol. 17, Pages 192: Pharmacological Modulators of Endoplasmic Reticulum Stress in Metabolic Diseases
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 1 ώρα
The endoplasmic reticulum (ER) is the principal organelle responsible for correct protein folding, a step in protein synthesis that is critical for the functional conformation of proteins. ER stress is a primary feature of secretory cells and is involved in the pathogenesis of numerous human diseases, such as certain neurodegenerative and cardiometabolic disorders. The unfolded […]
IJMS, Vol. 17, Pages 191: Prioritization of Susceptibility Genes for Ectopic Pregnancy by Gene Network Analysis
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 1 ώρα
Ectopic pregnancy is a very dangerous complication of pregnancy, affecting 1%–2% of all reported pregnancies. Due to ethical constraints on human biopsies and the lack of suitable animal models, there has been little success in identifying functionally important genes in the pathogenesis of ectopic pregnancy. In the present study, we developed a random walk–based computational […]
Roads to Melanoma: Key Pathways and Emerging Players in Melanoma Progression and Oncogenic Signaling
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 1 ώρα
Publication date: Available online 1 February 2016 Source:Biochimica et Biophysica Acta (BBA) – Molecular Cell Research Author(s): Jasmina Paluncic, Zaklina Kovacevic, Patric J. Jansson, Danuta Kalinowski, Angelica Merlot, Michael L.-H. Huang, Hiu Lok, Sumit Sahni, Darius J.R. Lane, Des R. Richardson Melanoma has markedly increased worldwide during the past several decades in the Caucasian population […]
Insufficient disease inhibition by intrathecal rituximab in progressive multiple sclerosis
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 1 ώρα
Abstract Objective Inaccessibility of the inflammation compartmentalized to the central nervous system (CNS) may underlie the lack of efficacy of immunomodulatory treatments in progressive multiple sclerosis (MS). The double blind combination of Rituximab by IntraVenous and IntraThecAl injection versus placebo in patients with Low-Inflammatory SEcondary progressive MS (RIVITALISE; NCT01212094) trial was designed to answer: (1) […]
Plasma neurofilament light chain predicts progression in progressive supranuclear palsy
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 1 ώρα
Abstract Objective Blood-based biomarkers for neurodegenerative conditions could improve diagnosis and treatment development. Neurofilament light chain (NfL), a marker of axonal injury, is elevated in cerebrospinal fluid (CSF) of patients with progressive supranuclear palsy (PSP). The goal of this study was to determine the diagnostic and prognostic value of plasma NfL in patients with PSP. […]
Parkinson disease and progressive supranuclear palsy: protein expression in skin
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 1 ώρα
Abstract Objective This study characterizes the expression of tau (p-tau) and α-synuclein (α-syn) by immunohistochemistry in the skin of three different populations: healthy control (HC), Parkinson disease (PD), and progressive supranuclear paralysis (PSP) subjects, with the purpose of finding a biomarker that could differentiate between subjects with PD and PSP. Material and Methods We evaluated […]
Analysis of Layperson Tourniquet Application Using a Novel Color-Coded Device
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 1 ώρα
Research Articles Craig Goolsby, Elizabeth Chen, Andrew Branting, Elizabeth Weissbrod, Jason David, Krista Moore, Cara Olsen Disaster Medicine and Public Health Preparedness,FirstView Article(s), 7 pages Abstract from #ORL-AlexandrosSfakianakis via simeraentaxei on Inoreader http://ift.tt/1WWXhDA via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
Voluntary Medical Support Is Key After Nuclear Disasters
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 1 ώρα
Letter Tomohiro Morita, Masaharu Tsubokura, Tsuyoshi Nemoto, Tomoyoshi Oikawa, Yukio Kanazawa Disaster Medicine and Public Health Preparedness,FirstView Article(s), 1 page Abstract from #ORL-AlexandrosSfakianakis via simeraentaxei on Inoreader http://ift.tt/1SwPCeM via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
Effect of Hurricane Sandy on Long Island Emergency Departments Visits
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 1 ώρα
Research Articles Hyun Kim, Rebecca M. Schwartz, Jerrold Hirsch, Robert Silverman, Bian Liu, Emanuela Taioli Disaster Medicine and Public Health Preparedness,FirstView Article(s), 7 pages Abstract from #ORL-AlexandrosSfakianakis via simeraentaxei on Inoreader http://ift.tt/1SwPBY3 via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
Characterizing Hospital Admissions to a Tertiary Care Hospital After Typhoon Haiyan
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 1 ώρα
Research Articles Mary P. Chang, Daren J. Simkin, Maria Lourdes de Lara, Thomas D. Kirsch Disaster Medicine and Public Health Preparedness,FirstView Article(s), 8 pages Abstract from #ORL-AlexandrosSfakianakis via simeraentaxei on Inoreader http://ift.tt/1SwPBHz via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
Frontotemporale Demenz: Keine Lust auf Demenztests
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Vergleichsstudie Patienten mit frontotemporaler Demenz fallen zwar oft durch Verhaltensänderungen auf, haben aber auch deutliche Defizite bei der Exekutivfunktion. So schwindet vor allem die Fähigkeit, Fehler zu erkennen. from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1nzhnrn via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
Analysis of Layperson Tourniquet Application Using a Novel Color-Coded Device
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Research Articles Craig Goolsby, Elizabeth Chen, Andrew Branting, Elizabeth Weissbrod, Jason David, Krista Moore, Cara Olsen Disaster Medicine and Public Health Preparedness,FirstView Article(s), 7 pages Abstract from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1WWXhDA via IFTTT
Voluntary Medical Support Is Key After Nuclear Disasters
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Letter Tomohiro Morita, Masaharu Tsubokura, Tsuyoshi Nemoto, Tomoyoshi Oikawa, Yukio Kanazawa Disaster Medicine and Public Health Preparedness,FirstView Article(s), 1 page Abstract from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1SwPCeM via IFTTT
Effect of Hurricane Sandy on Long Island Emergency Departments Visits
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Research Articles Hyun Kim, Rebecca M. Schwartz, Jerrold Hirsch, Robert Silverman, Bian Liu, Emanuela Taioli Disaster Medicine and Public Health Preparedness,FirstView Article(s), 7 pages Abstract from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1SwPBY3 via IFTTT
Characterizing Hospital Admissions to a Tertiary Care Hospital After Typhoon Haiyan
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Research Articles Mary P. Chang, Daren J. Simkin, Maria Lourdes de Lara, Thomas D. Kirsch Disaster Medicine and Public Health Preparedness,FirstView Article(s), 8 pages Abstract from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1SwPBHz via IFTTT
Strip of the Month: February 2016
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1PPvA08 via IFTTT
Impact of Obesity on Uteroplacental Immunology and Placental Pathology
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Obesity is a growing problem. Currently 1 in 3 reproductive-age women is obese. This is significant because obesity is associated with an increased risk of gestational diabetes mellitus (GDM), preterm birth, fetal growth abnormalities, preeclampsia, and stillbirth. Obesity alone increases the risk of stillbirth by threefold, whereas GDM increases this risk to approximately 10-fold. How […]
Case 1: Recurrent Apnea in a Preterm Neonate
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1PPvxBx via IFTTT
Chronic Inflammatory Lesions of the Placenta and Preterm Birth
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
A successful pregnancy largely relies on proper immune regulation in the gravid uterus. This review describes immune mechanisms that permit the fetal allograft to continue to grow to term. Chronic inflammatory lesions may be manifestations of altered immune status in the placenta and are often present in preterm placentas. These lesions are compared with the […]
Educational Perspectives: Personal, Professional, and Practice–A Framework for Ethics Education
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Health care professionals commonly encounter ethical issues in neonatology as part of their clinical practice. How they approach different situations that require ethical and legal consideration depends on the interaction among their personal values, their profession’s values and obligations, and the conduct of their profession’s practice as a whole. This relationship between the personal, the […]
Insufficient disease inhibition by intrathecal rituximab in progressive multiple sclerosis
Abstract Objective Inaccessibility of the inflammation compartmentalized to the central nervous system (CNS) may underlie the lack of efficacy of immunomodulatory treatments in progressive multiple sclerosis (MS). The double blind combination of Rituximab by IntraVenous and IntraThecAl injection versus placebo in patients with Low-Inflammatory SEcondary progressive MS (RIVITALISE; NCT01212094) trial was designed to answer: (1) Whether an induction dose of intravenous and intrathecal rituximab efficiently depletes CNS B cells? and (2) If so, whether this leads to global inhibition... περισσότερα »
Plasma neurofilament light chain predicts progression in progressive supranuclear palsy
Abstract Objective Blood-based biomarkers for neurodegenerative conditions could improve diagnosis and treatment development. Neurofilament light chain (NfL), a marker of axonal injury, is elevated in cerebrospinal fluid (CSF) of patients with progressive supranuclear palsy (PSP). The goal of this study was to determine the diagnostic and prognostic value of plasma NfL in patients with PSP. Methods Plasma NfL was measured with ultrasensitive digital immunoassay-based technology at baseline and 1-year follow-up in a pilot cohort of 15 PSP patients and 12 healthy controls, and a v...περισσότερα »
Parkinson disease and progressive supranuclear palsy: protein expression in skin
Abstract Objective This study characterizes the expression of tau (p-tau) and *α*-synuclein ( *α*-syn) by immunohistochemistry in the skin of three different populations: healthy control (HC), Parkinson disease (PD), and progressive supranuclear paralysis (PSP) subjects, with the purpose of finding a biomarker that could differentiate between subjects with PD and PSP. Material and Methods We evaluated the presence of p-tau and *α*-syn in a pilot study in the skin of three distinct groups of patients: 17 healthy subjects, 17 patients with PD, and 10 patients with PSP. Four millimet...περισσότερα »
OtoRhinoLaryngology & Medicine,New Articles,February 1st,2016
Chronic pain may be linked to genetic changes in the immune system medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 2 δευτερόλεπτα Chronic pain following injury may involve epigenetic changes, implying a potential future role for medications that target specific genes. from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1PPn417 via IFTTT Neural networks adapt to the presence of a toxic HIV protein medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,An... περισσότερα »
Improvement of the Marginal Reflex Distance-1 in Blepharoptosis Surgeries.
Improvement of the Marginal Reflex Distance-1 in Blepharoptosis Surgeries.: The aim of this study was to predict the improvement of the marginal reflex distance (MRD1) in each blepharoptosis surgery. In PubMed and Scopus, the search terms 1. (blepharoptosis) AND 2. (surgery) AND 3. (levator OR outcome OR MRD OR function OR ptosis amount) were used and 1268 titles were found. Among them 28 papers were analyzed: Aponeurotic surgery (A-group, 8), Muller muscle resection (M-group, 10), Levator resection (L-group, 4), and Frontalis suspension (F-group, 6). The preop-MRD1 was greatest in L-... περισσότερα »
The YY1/MMP2 axis promotes trophoblast invasion at the maternal-foetal interface
Abstract YY1 is a sequence-specific DNA-binding transcription factor that has many important biological roles. However, its function in trophoblasts at the maternal-foetal interface remains to be elucidated. In this study, we used an mRNA microarray and reverse transcription qPCR and compared the *YY1* mRNA expression level in trophoblasts between patients with recurrent miscarriage (RM) and healthy control subjects. Our results revealed that *YY1* mRNA expression was significantly lower in the trophoblasts of the RM group compared with the healthy control group. Furthermore, immu...περισσότερα »
Clonality analysis of multifocal papillary thyroid carcinoma by using genetic profiles
Abstract Papillary thyroid carcinoma (PTC) is the most common adult thyroid malignancy and often presents with multiple anatomically distinct foci within the thyroid, known as multifocal papillary thyroid carcinoma (MPTC). The widespread application of the next-generation sequencing technologies in cancer genomics research provides novel insights into determining the clonal relationship between multiple tumours within the same thyroid gland. For eight MPTC patients, we performed whole-exome sequencing and targeted region sequencing to identify the non-synonymous point mutations and...περισσότερα »
UTEP professor shows that hearing aids improve memory, speech
A recent study by Jamie Desjardins, Ph.D., an assistant professor in the speech-language pathology program at The University of Texas at El Paso, found that hearing aids improve brain function in... from #Audiology via ola Kala on Inoreader http://ift.tt/1Q6rURH via IFTTT
Polymers, Vol. 8, Pages 38: Comb-Type Grafted Hydrogels of PNIPAM and PDMAEMA with Reversed Network-Graft Architectures from Controlled Radical Polymerizations
Dual thermo- and pH-responsive comb-type grafted hydrogels of poly(N,N-dimethylaminoethyl methacrylate) (PDMAEMA) and poly(N-isopropylacrylamide) (PNIPAM) with reversed network-graft architectures were synthesized by the combination of atom transfer radical polymerization (ATRP), reversible addition-fragmentation chain transfer (RAFT) polymerization and click chemistry. Two kinds of macro-cross-linkers with two azido groups at one chain-end and different chain length [PNIPAM–(N3)2 and PDMAEMA–(N3)2] were prepared with N,N-di(β-azidoethyl) 2-halocarboxylamide as the ATRP initiator....περισσότερα »
Gels, Vol. 2, Pages 7: Supramolecular Assembly of pH-Sensitive Triphenylene Derived π-Gelators and Their Application as Molecular Template for the Preparation of Silica Nanotubes
The gelation properties and mode of self-assembly of six asymmetrical hexaether triphenylene derivatives mono-functionalized with carboxylic and primary amine groups were investigated. The presence of a carboxylic and amine group attached to the triphenylene core generated stable, thermo- and pH-sensitive supramolecular π-organogels with a reversible response to both stimuli. In order to understand the gelation process, we studied the effect of the spacer length and found a different gelation scope for the acid and basic derivatives that accounts for a different supramolecular sel... περισσότερα »
Diagnostics, Vol. 6, Pages 8: Interobserver and Intraobserver Reproducibility with Volume Dynamic Contrast Enhanced Computed Tomography (DCE-CT) in Gastroesophageal Junction Cancer
The purpose of this study was to assess inter- and intra-observer reproducibility of three different analytic methods to evaluate quantitative dynamic contrast-enhanced computed tomography (DCE-CT) measures from gastroesophageal junctional cancer. Twenty-five DCE-CT studies with gastroesophageal junction cancer were selected from a previous longitudinal study. Three radiologists independently reviewed all scans, and one repeated the analysis eight months later for intraobserver analysis. Review of the scans consisted of three analysis methods: (I) Four, fixed small sized regions o...περισσότερα »
IJMS, Vol. 17, Pages 193: The Role of Endoplasmic Reticulum Stress and Unfolded Protein Response in Atherosclerosis
Pathogenesis of atherosclerosis is a complex process involving several metabolic and signalling pathways. Accumulating evidence demonstrates that endoplasmic reticulum stress and associated apoptosis can be induced in the pathological conditions of atherosclerotic lesions and contribute to the disease progression. Notably, they may play a role in the development of vulnerable plaques that induce thrombosis and are therefore especially dangerous. Endoplasmic reticulum stress response is regulated by several signaling mechanisms that involve protein kinases and transcription factors...περισσότερα »
IJMS, Vol. 17, Pages 191: Prioritization of Susceptibility Genes for Ectopic Pregnancy by Gene Network Analysis
Ectopic pregnancy is a very dangerous complication of pregnancy, affecting 1%–2% of all reported pregnancies. Due to ethical constraints on human biopsies and the lack of suitable animal models, there has been little success in identifying functionally important genes in the pathogenesis of ectopic pregnancy. In the present study, we developed a random walk–based computational method named TM-rank to prioritize ectopic pregnancy–related genes based on text mining data and gene network information. Using a defined threshold value, we identified five top-ranked genes: VEGFA (vascula...περισσότερα »
IJMS, Vol. 17, Pages 192: Pharmacological Modulators of Endoplasmic Reticulum Stress in Metabolic Diseases
The endoplasmic reticulum (ER) is the principal organelle responsible for correct protein folding, a step in protein synthesis that is critical for the functional conformation of proteins. ER stress is a primary feature of secretory cells and is involved in the pathogenesis of numerous human diseases, such as certain neurodegenerative and cardiometabolic disorders. The unfolded protein response (UPR) is a defense mechanism to attenuate ER stress and maintain the homeostasis of the organism. Two major degradation systems, including the proteasome and autophagy, are involved in this ... περισσότερα »
Molecules, Vol. 21, Pages 181: Thiourea-Modified TiO2 Nanorods with Enhanced Photocatalytic Activity
Semiconductor TiO2 photocatalysis has attracted much attention due to its potential application in solving the problems of environmental pollution. In this paper, thiourea (CH4N2S) modified anatase TiO2 nanorods were fabricated by calcination of the mixture of TiO2 nanorods and thiourea at 600 °C for 2 h. It was found that only N element was doped into the lattice of TiO2 nanorods. With increasing the weight ratio of thiourea to TiO2 (R) from 0 to 8, the light-harvesting ability of the photocatalyst steady increases. Both the crystallization and photocatalytic activity of TiO2 nan... περισσότερα »
Sensors, Vol. 16, Pages 181: Accuracy and Resolution Analysis of a Direct Resistive Sensor Array to FPGA Interface
Resistive sensor arrays are formed by a large number of individual sensors which are distributed in different ways. This paper proposes a direct connection between an FPGA and a resistive array distributed in M rows and N columns, without the need of analog-to-digital converters to obtain resistance values in the sensor and where the conditioning circuit is reduced to the use of a capacitor in each of the columns of the matrix. The circuit allows parallel measurements of the N resistors which form each of the rows of the array, eliminating the resistive crosstalk which is typical ... περισσότερα »
Sensors, Vol. 16, Pages 180: A Personal, Distributed Exposimeter: Procedure for Design, Calibration, Validation, and Application
This paper describes, for the first time, the procedure for the full design, calibration, uncertainty analysis, and practical application of a personal, distributed exposimeter (PDE) for the detection of personal exposure in the Global System for Mobile Communications (GSM) downlink (DL) band around 900 MHz (GSM 900 DL). The PDE is a sensor that consists of several body-worn antennas. The on-body location of these antennas is investigated using numerical simulations and calibration measurements in an anechoic chamber. The calibration measurements and the simulations result in a de...περισσότερα »
Aerospace, Vol. 3, Pages 5: Target Tracking in 3-D Using Estimation Based Nonlinear Control Laws for UAVs
This paper presents an estimation based backstepping like control law design for an Unmanned Aerial Vehicle (UAV) to track a moving target in 3-D space. A ground-based sensor or an onboard seeker antenna provides range, azimuth angle, and elevation angle measurements to a chaser UAV that implements an extended Kalman filter (EKF) to estimate the full state of the target. A nonlinear controller then utilizes this estimated target state and the chaser's state to provide speed, flight path, and course/heading angle commands to the chaser UAV. Tracking performance with respect to meas...περισσότερα »
Polymers, Vol. 8, Pages 38: Comb-Type Grafted Hydrogels of PNIPAM and PDMAEMA with Reversed Network-Graft Architectures from Controlled Radical Polymerizations
Dual thermo- and pH-responsive comb-type grafted hydrogels of poly(N,N-dimethylaminoethyl methacrylate) (PDMAEMA) and poly(N-isopropylacrylamide) (PNIPAM) with reversed network-graft architectures were synthesized by the combination of atom transfer radical polymerization (ATRP), reversible addition-fragmentation chain transfer (RAFT) polymerization and click chemistry. Two kinds of macro-cross-linkers with two azido groups at one chain-end and different chain length [PNIPAM–(N3)2 and PDMAEMA–(N3)2] were prepared with N,N-di(β-azidoethyl) 2-halocarboxylamide as the ATRP initiator....περισσότερα »
Gels, Vol. 2, Pages 7: Supramolecular Assembly of pH-Sensitive Triphenylene Derived π-Gelators and Their Application as Molecular Template for the Preparation of Silica Nanotubes
The gelation properties and mode of self-assembly of six asymmetrical hexaether triphenylene derivatives mono-functionalized with carboxylic and primary amine groups were investigated. The presence of a carboxylic and amine group attached to the triphenylene core generated stable, thermo- and pH-sensitive supramolecular π-organogels with a reversible response to both stimuli. In order to understand the gelation process, we studied the effect of the spacer length and found a different gelation scope for the acid and basic derivatives that accounts for a different supramolecular sel... περισσότερα »
Diagnostics, Vol. 6, Pages 8: Interobserver and Intraobserver Reproducibility with Volume Dynamic Contrast Enhanced Computed Tomography (DCE-CT) in Gastroesophageal Junction Cancer
The purpose of this study was to assess inter- and intra-observer reproducibility of three different analytic methods to evaluate quantitative dynamic contrast-enhanced computed tomography (DCE-CT) measures from gastroesophageal junctional cancer. Twenty-five DCE-CT studies with gastroesophageal junction cancer were selected from a previous longitudinal study. Three radiologists independently reviewed all scans, and one repeated the analysis eight months later for intraobserver analysis. Review of the scans consisted of three analysis methods: (I) Four, fixed small sized regions o...περισσότερα »
Remote Sensing, Vol. 8, Pages 109: A Combination of Plant NDVI and LiDAR Measurements Improve the Estimation of Pasture Biomass in Tall Fescue (Festuca arundinacea var. Fletcher)
The total biomass of a tall fescue (Festuca arundinacea var. Fletcher) pasture was assessed by using a vehicle mounted light detection and ranging (LiDAR) unit to derive canopy height and an active optical reflectance sensor to determine the spectro-optical reflectance index, normalized difference vegetation index (NDVI). In a random plot design, measurements of NDVI and pasture height were combined to estimate biomass with a root mean square error of prediction (RMSEP) equal to ±455.28 kg green dry matter (GDM)/ha, over a range of 286 kg to 3933 kg GDM/ha. The combination of NDVI... περισσότερα »
IJMS, Vol. 17, Pages 91: Biological Evaluation of Double Point Modified Analogues of 1,25-Dihydroxyvitamin D2 as Potential Anti-Leukemic Agents
Structurally similar double-point modified analogues of 1,25-dihydroxyvitamin D2 (1,25D2) were screened in vitro for their pro-differentiating activity against the promyeloid cell line HL60. Their affinities towards human full length vitamin D receptor (VDR) and metabolic stability against human vitamin D 24-hydroxylase (CYP24A1) were also tested. The analogues (PRI-1730, PRI-1731, PRI-1732, PRI-1733 and PRI-1734) contained 5,6-trans modification of the A-ring and of the triene system, additional hydroxyl or unsaturation at C-22 in the side chain and reversed absolute configuratio... περισσότερα »
Microfluidic devices with templated regular macroporous structures for HIV viral capture
[image: GA?id=C5AN02282G] *Analyst*, 2016, Advance Article *DOI*: 10.1039/C5AN02282G, Paper Krissada Surawathanawises, Kathryn Kundrod, Xuanhong Cheng Microfluidic devices with embedded macroporous matrices significantly improve the capture yield of HIV viruses through affinity binding. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry from #Medicine via ola Kala on Inoreader http://ift.tt/1SwD1bt Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece... περισσότερα »
Diagnostic criteria for hepatocellular carcinoma Ͳ3 cm with hepatocyte-specific contrast-enhanced magnetic resonance imaging
Journal of Hepatology from #Medicine via ola Kala on Inoreader http://ift.tt/1SwD3jn Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
Effects of cancer stage and treatment differences on racial disparities in survival from colon cancer: A United States population-based study
Gastroenterology from #Medicine via ola Kala on Inoreader http://ift.tt/1nz8sWH Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
Helicobacter pylori and antibiotic resistance, a continuing and intractable problem
Helicobacter from #Medicine via ola Kala on Inoreader http://ift.tt/1nz8qOH Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
Cohort study of the impact of direct acting antiviral therapy in patients with chronic hepatitis C and decompensated cirrhosis
Journal of Hepatology from #Medicine via ola Kala on Inoreader http://ift.tt/1SwD0UR Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
Hepatitis B virus X protein induces hepatic steatosis by enhancing the expression of liver fatty acid binding protein
Journal of Virology from #Medicine via ola Kala on Inoreader http://ift.tt/1SwD2MB Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
In depth analysis of clotting dynamics in burn patients
Journal of Surgical Research from Emergency Medicine via ola Kala on Inoreader http://ift.tt/1nYnyFI via IFTTT
The effect of a researcher designated music intervention on hospitalised psychiatric patients with different levels of anxiety
Journal of Clinical Nursing from Emergency Medicine via ola Kala on Inoreader http://ift.tt/1nYnypg via IFTTT
Hospital's missed Ebola diagnosis calls for organizational mindfulness
University of Houston News from Emergency Medicine via ola Kala on Inoreader http://ift.tt/1WWTOoF via IFTTT
Diagnostic value of end tidal capnography in patients with hyperglycemia in the emergency department
BMC Emergency Medicine from Emergency Medicine via ola Kala on Inoreader http://ift.tt/20i3LCv via IFTTT
New app could help predict child's asthma attack
Keck School of Medicine of USC - Research News from Emergency Medicine via ola Kala on Inoreader http://ift.tt/1VBETyX via IFTTT
Polymers, Vol. 8, Pages 38: Comb-Type Grafted Hydrogels of PNIPAM and PDMAEMA with Reversed Network-Graft Architectures from Controlled Radical Polymerizations
Dual thermo- and pH-responsive comb-type grafted hydrogels of poly(N,N-dimethylaminoethyl methacrylate) (PDMAEMA) and poly(N-isopropylacrylamide) (PNIPAM) with reversed network-graft architectures were synthesized by the combination of atom transfer radical polymerization (ATRP), reversible addition-fragmentation chain transfer (RAFT) polymerization and click chemistry. Two kinds of macro-cross-linkers with two azido groups at one chain-end and different chain length [PNIPAM–(N3)2 and PDMAEMA–(N3)2] were prepared with N,N-di(β-azidoethyl) 2-halocarboxylamide as the ATRP initiator....περισσότερα »
Microfluidic devices with templated regular macroporous structures for HIV viral capture
[image: GA?id=C5AN02282G] *Analyst*, 2016, Advance Article *DOI*: 10.1039/C5AN02282G, Paper Krissada Surawathanawises, Kathryn Kundrod, Xuanhong Cheng Microfluidic devices with embedded macroporous matrices significantly improve the capture yield of HIV viruses through affinity binding. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry [image: 1nz8rlE] from #Medicine via ola Kala on Inoreader http://ift.tt/1SwD1bt Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Cre... περισσότερα »
Diagnostics, Vol. 6, Pages 8: Interobserver and Intraobserver Reproducibility with Volume Dynamic Contrast Enhanced Computed Tomography (DCE-CT) in Gastroesophageal Junction Cancer
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 1 ώρα
The purpose of this study was to assess inter- and intra-observer reproducibility of three different analytic methods to evaluate quantitative dynamic contrast-enhanced computed tomography (DCE-CT) measures from gastroesophageal junctional cancer. Twenty-five DCE-CT studies with gastroesophageal junction cancer were selected from a previous longitudinal study. Three radiologists independently reviewed all scans, and one repeated the analysis […]
PulmCrit- Intravenous olanzapine: Faster than IM olanzapine, safer than IV haloperidol?
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 1 ώρα
Is IV olanzapine ready for prime time? This boils down to a choice of the devil that we know (haloperidol) versus the devil that we don’t entirely know (olanzapine). IV olanzapine is newer, so it is possible that additional side effects may emerge over time. However, we already know that there are significant problems with […]
Erratum
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 1 ώρα
Future Oncology Ahead of Print. from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1OZXC5p via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/202kkwV via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1SmHcbA via IFTTT
IJMS, Vol. 17, Pages 193: The Role of Endoplasmic Reticulum Stress and Unfolded Protein Response in Atherosclerosis
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 1 ώρα
Pathogenesis of atherosclerosis is a complex process involving several metabolic and signalling pathways. Accumulating evidence demonstrates that endoplasmic reticulum stress and associated apoptosis can be induced in the pathological conditions of atherosclerotic lesions and contribute to the disease progression. Notably, they may play a role in the development of vulnerable plaques that induce thrombosis and […]
IJMS, Vol. 17, Pages 191: Prioritization of Susceptibility Genes for Ectopic Pregnancy by Gene Network Analysis
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 1 ώρα
Ectopic pregnancy is a very dangerous complication of pregnancy, affecting 1%–2% of all reported pregnancies. Due to ethical constraints on human biopsies and the lack of suitable animal models, there has been little success in identifying functionally important genes in the pathogenesis of ectopic pregnancy. In the present study, we developed a random walk–based computational […]
Sensors, Vol. 16, Pages 181: Accuracy and Resolution Analysis of a Direct Resistive Sensor Array to FPGA Interface
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 1 ώρα
Resistive sensor arrays are formed by a large number of individual sensors which are distributed in different ways. This paper proposes a direct connection between an FPGA and a resistive array distributed in M rows and N columns, without the need of analog-to-digital converters to obtain resistance values in the sensor and where the conditioning […]
IJMS, Vol. 17, Pages 192: Pharmacological Modulators of Endoplasmic Reticulum Stress in Metabolic Diseases
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 1 ώρα
The endoplasmic reticulum (ER) is the principal organelle responsible for correct protein folding, a step in protein synthesis that is critical for the functional conformation of proteins. ER stress is a primary feature of secretory cells and is involved in the pathogenesis of numerous human diseases, such as certain neurodegenerative and cardiometabolic disorders. The unfolded […]
Molecules, Vol. 21, Pages 181: Thiourea-Modified TiO2 Nanorods with Enhanced Photocatalytic Activity
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 1 ώρα
Semiconductor TiO2 photocatalysis has attracted much attention due to its potential application in solving the problems of environmental pollution. In this paper, thiourea (CH4N2S) modified anatase TiO2 nanorods were fabricated by calcination of the mixture of TiO2 nanorods and thiourea at 600 °C for 2 h. It was found that only N element was doped […]
Sensors, Vol. 16, Pages 180: A Personal, Distributed Exposimeter: Procedure for Design, Calibration, Validation, and Application
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 1 ώρα
This paper describes, for the first time, the procedure for the full design, calibration, uncertainty analysis, and practical application of a personal, distributed exposimeter (PDE) for the detection of personal exposure in the Global System for Mobile Communications (GSM) downlink (DL) band around 900 MHz (GSM 900 DL). The PDE is a sensor that consists […]
Aerospace, Vol. 3, Pages 5: Target Tracking in 3-D Using Estimation Based Nonlinear Control Laws for UAVs
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 1 ώρα
This paper presents an estimation based backstepping like control law design for an Unmanned Aerial Vehicle (UAV) to track a moving target in 3-D space. A ground-based sensor or an onboard seeker antenna provides range, azimuth angle, and elevation angle measurements to a chaser UAV that implements an extended Kalman filter (EKF) to estimate the […]
PulmCrit- Intravenous olanzapine: Faster than IM olanzapine, safer than IV haloperidol?
Alexandros G. SfakianakisστοRehabilitation,Sports and Exercise Medicine by Alexandros G. SfakianakisΠριν από 1 ώρα
[image: reaper77.png?resize=1418%2C249] Is IV olanzapine ready for prime time? This boils down to a choice of the devil that we know (haloperidol) versus the devil that we don't entirely know (olanzapine). IV olanzapine is newer, so it is possible that additional side effects may emerge over time. However, we already know that there are significant problems with IV haloperidol. EMCrit by Josh Farkas. from #Rehabilitation via ola Kala on Inoreader http://ift.tt/1KRKwDl via IFTTT
The regenerative role of adipose-derived stem cells (ADSC) in plastic and reconstructive surgery
Abstract The potential use of stem cell-based therapies for the repair and regeneration of various tissues and organs offers a paradigm shift in plastic and reconstructive surgery. The use of either embryonic stem cells (ESC) or induced pluripotent stem cells (iPSC) in clinical situations is limited because of regulations and ethical considerations even though these cells are theoretically highly beneficial. Adult mesenchymal stem cells appear to be an ideal stem cell population for practical regenerative medicine. Among these cells, adipose-derived stem cells (ADSC) have the pote... περισσότερα »
Traumatic Brain Injury and Obesity Induce Persistent Central Insulin Resistance
Abstract Traumatic brain injury (TBI)-induced impairments in cerebral energy metabolism impede tissue repair and contribute to delayed functional recovery. Moreover, the transient alteration in brain glucose utilization corresponds to a period of increased vulnerability to the negative effects of a subsequent TBI. In order to better understand the contributing factors to TBI-induced central metabolic dysfunction, we examined the effect of single and repeated TBIs on brain insulin signaling. Here we show that TBI induces acute brain insulin resistance, which resolves within 7 days ... περισσότερα »
Diagnostics, Vol. 6, Pages 8: Interobserver and Intraobserver Reproducibility with Volume Dynamic Contrast Enhanced Computed Tomography (DCE-CT) in Gastroesophageal Junction Cancer
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
The purpose of this study was to assess inter- and intra-observer reproducibility of three different analytic methods to evaluate quantitative dynamic contrast-enhanced computed tomography (DCE-CT) measures from gastroesophageal junctional cancer. Twenty-five DCE-CT studies with gastroesophageal junction cancer were selected from a previous longitudinal study. Three radiologists independently reviewed all scans, and one repeated the analysis […]
Erratum
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Future Oncology Ahead of Print. from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1OZXC5p via IFTTT
Erratum
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Future Oncology Ahead of Print. from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1OZXC5p via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
Erratum
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Future Oncology Ahead of Print. from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1OZXC5p via IFTTT
Experimental Evolution
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Evolutionary processes have traditionally been tricky to observe. They were long thought to take place over too long timeframes to make useful records and can be difficult to replicate in laboratory settings. As part of our series of ‘CSEE Reviews’, the 2015 Canadian Society for Ecology and Evolution (CSEE) biannual prizewinner Professor Graham Bell explores […]
Erratum
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Future Oncology Ahead of Print. from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1OZXC5p via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
Experimental Evolution
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Evolutionary processes have traditionally been tricky to observe. They were long thought to take place over too long timeframes to make useful records and can be difficult to replicate in laboratory settings. As part of our series of ‘CSEE Reviews’, the 2015 Canadian Society for Ecology and Evolution (CSEE) biannual prizewinner Professor Graham Bell explores […]
Chronic pain may be linked to genetic changes in the immune system
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Chronic pain following injury may involve epigenetic changes, implying a potential future role for medications that target specific genes. from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1PPn417 via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
Neural networks adapt to the presence of a toxic HIV protein
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
HIV-associated neurocognitive disorders (HAND) afflict approximately half of HIV infected patients.Nearly half of HIV infected patients suffer from impaired neurocognitive function. from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1PPmUGX via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
Practice makes perfect, York U brain study confirms
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
In this study, Faculty of Health researchers were looking at fMRI brain scans of professional ballet dancers to measure the long-term effects of learning. from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1nYiTnf via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
Practice makes perfect, York U brain study confirms
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 2 ώρες
In this study, Faculty of Health researchers were looking at fMRI brain scans of professional ballet dancers to measure the long-term effects of learning. from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1nYiTnf via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1SwEgaA via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros […]
Chronic pain may be linked to genetic changes in the immune system
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 2 ώρες
Chronic pain following injury may involve epigenetic changes, implying a potential future role for medications that target specific genes. from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1PPn417 via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1PLpFmD via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1nzama3 via […]
Neural networks adapt to the presence of a toxic HIV protein
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 2 ώρες
HIV-associated neurocognitive disorders (HAND) afflict approximately half of HIV infected patients.Nearly half of HIV infected patients suffer from impaired neurocognitive function. from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1PPmUGX via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1PLpFmv via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader […]
Scuba Diving After Extensive Head and Neck Reconstructive Surgery: Is it Possible?.
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 2 ώρες
Scuba Diving After Extensive Head and Neck Reconstructive Surgery: Is it Possible? from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1Q6siQ8 via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1PLqjQZ via IFTTT
Systematic review with network meta-analysis: comparative effectiveness of topical steroids vs. PPIs for the treatment of the spectrum of eosinophilic oesophagitis
Summary Background Controversy surrounds the clinical and histological response to topical steroids in patients with eosinophilic oesophagitis (EoE). Aim To perform a systematic review and network meta-analysis of randomised controlled trials to assess the efficacy of topical steroids compared with placebo or proton pump inhibitor (PPIs) for the management of eosinophilic oesophagitis. Methods Cochrane Central Register of Controlled Trials and MEDLINE from inception to 1 July 2015 was searched. Data were extracted independently by two authors. Methodological quality was assesse... περισσότερα »
Prevalence of hepatitis C virus infection among HIV+ men who have sex with men: A systematic review and meta-analysis
International Journal of STD & AIDS from #Medicine via ola Kala on Inoreader http://ift.tt/1nz8pKx Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
Neonatal hyperbilirubinaemia
Paediatrics and Child Health from #Medicine via ola Kala on Inoreader http://ift.tt/1SwD2Ml Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
Remote Sensing, Vol. 8, Pages 109: A Combination of Plant NDVI and LiDAR Measurements Improve the Estimation of Pasture Biomass in Tall Fescue (Festuca arundinacea var. Fletcher)
The total biomass of a tall fescue (Festuca arundinacea var. Fletcher) pasture was assessed by using a vehicle mounted light detection and ranging (LiDAR) unit to derive canopy height and an active optical reflectance sensor to determine the spectro-optical reflectance index, normalized difference vegetation index (NDVI). In a random plot design, measurements of NDVI and pasture height were combined to estimate biomass with a root mean square error of prediction (RMSEP) equal to ±455.28 kg green dry matter (GDM)/ha, over a range of 286 kg to 3933 kg GDM/ha. The combination of NDVI... περισσότερα »
IJMS, Vol. 17, Pages 91: Biological Evaluation of Double Point Modified Analogues of 1,25-Dihydroxyvitamin D2 as Potential Anti-Leukemic Agents
Structurally similar double-point modified analogues of 1,25-dihydroxyvitamin D2 (1,25D2) were screened in vitro for their pro-differentiating activity against the promyeloid cell line HL60. Their affinities towards human full length vitamin D receptor (VDR) and metabolic stability against human vitamin D 24-hydroxylase (CYP24A1) were also tested. The analogues (PRI-1730, PRI-1731, PRI-1732, PRI-1733 and PRI-1734) contained 5,6-trans modification of the A-ring and of the triene system, additional hydroxyl or unsaturation at C-22 in the side chain and reversed absolute configuratio... περισσότερα »
Microfluidic devices with templated regular macroporous structures for HIV viral capture
[image: GA?id=C5AN02282G] *Analyst*, 2016, Advance Article *DOI*: 10.1039/C5AN02282G, Paper Krissada Surawathanawises, Kathryn Kundrod, Xuanhong Cheng Microfluidic devices with embedded macroporous matrices significantly improve the capture yield of HIV viruses through affinity binding. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry from #Medicine via ola Kala on Inoreader http://ift.tt/1SwD1bt Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece... περισσότερα »
Diagnostic criteria for hepatocellular carcinoma Ͳ3 cm with hepatocyte-specific contrast-enhanced magnetic resonance imaging
Journal of Hepatology from #Medicine via ola Kala on Inoreader http://ift.tt/1SwD3jn Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
Effects of cancer stage and treatment differences on racial disparities in survival from colon cancer: A United States population-based study
Gastroenterology from #Medicine via ola Kala on Inoreader http://ift.tt/1nz8sWH Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
Helicobacter pylori and antibiotic resistance, a continuing and intractable problem
Helicobacter from #Medicine via ola Kala on Inoreader http://ift.tt/1nz8qOH Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
Cohort study of the impact of direct acting antiviral therapy in patients with chronic hepatitis C and decompensated cirrhosis
Journal of Hepatology from #Medicine via ola Kala on Inoreader http://ift.tt/1SwD0UR Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
Hepatitis B virus X protein induces hepatic steatosis by enhancing the expression of liver fatty acid binding protein
Journal of Virology from #Medicine via ola Kala on Inoreader http://ift.tt/1SwD2MB Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
Prevalence of hepatitis C virus infection among HIV+ men who have sex with men: A systematic review and meta-analysis
International Journal of STD & AIDS from #Medicine via ola Kala on Inoreader http://ift.tt/1nz8pKx Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
Neonatal hyperbilirubinaemia
Paediatrics and Child Health from #Medicine via ola Kala on Inoreader http://ift.tt/1SwD2Ml Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174 from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1SwEdeQ via IFTTT
Daclatasvir, sofosbuvir, and ribavirin for hepatitis C virus genotype 3 and advanced liver disease: A randomized phase III study (ALLY-3+)
Hepatology from #Medicine via ola Kala on Inoreader http://ift.tt/1nz8nm2 Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174 from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1PLpEPv via IFTTT
Significant intratumoral heterogeneity of HER2 status in gastric cancer: A comparative study among IHC, FISH, and DISH
Cancer Science from #Medicine via ola Kala on Inoreader http://ift.tt/1SwD2fn Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174 from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1SwEdeI via IFTTT
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