These new articles for The Journal of Clinical Endocrinology & Metabolism are available online
These new articles for The Journal of Clinical Endocrinology & Metabolism are available online ------------------------------ Early Release The Journal of Clinical Endocrinology & Metabolism ------------------------------ [image: Journal of Clinical Endocrinology & Metabolism masthead] ------------------------------ ------------------------------ The Journal of Clinical Endocrinology & Metabolism Home Page Current Issue Past Issues ------------------------------ ------------------------------ ------------------------------ ------------------------------ Lipids, Lipoproteins, and Car... περισσότερα »
Access to Support System and Learners Response about Dairy Farming Distance Education Programme
AlexAndros SfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026Πριν από 6 δευτερόλεπτα
2016-02-24T00-33-15Z *Source:* International Journal of Livestock Research Senthilkumar Thayalan. It is evident from the study, that an overwhelming majority of the respondents had indicated that the minimum required support services for the learners were provided by the distance education course providers and the institution. Also the respondents might have been satisfied due to easier access, friendly faculties who had interacted, simple and understandable course content in vernacular language and flexibility of the course, which would strengthen the learning outcomes, leading to ... περισσότερα »
Kidney-specific knockout of Sav1 in the mouse promotes hyper-proliferation of renal tubular epithelium through suppression of the Hippo pathway
Abstract Previously, we have reported that Salvador homolog 1 (SAV1), a component of the Hippo pathway, is significantly downregulated in high-grade clear cell renal cell carcinoma (ccRCC) due to 14q copy number loss, and that this downregulation contributes to the proliferation and survival of renal tubular epithelial cells through activation of Yes-associated protein 1 (YAP1),… Continue reading Kidney-specific knockout of Sav1 in the mouse promotes hyper-proliferation of renal tubular epithelium through suppression of the Hippo pathway
Localized soft elasticity in liquid crystal elastomers
Article Ruggedized stretchable electronic devices motivate the development of globally stretchable yet locally stiff materials. Here, Ware et al . programme the self-organization of liquid crystal elastomers to yield stretchable materials of homogenous composition but with spatial variation in mechanical properties. Nature Communications doi: 10.1038/ncomms10781 Authors: Taylor H. Ware, John S. Biggins, Andreas F. Shick,… Continue reading Localized soft elasticity in liquid crystal elastomers
Editorial.
No abstract available from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1Qbxfb6 via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/21eRYFz via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/20UxgFp via IFTTT
Aharonov–Bohm oscillations in Dirac semimetal Cd3As2 nanowires
Article Dirac semimetals are a three-dimensional analogue of graphene that can support massless Dirac fermions in their bulk and Fermi-arc surface states. Here, the authors observe Aharonov–Bohm oscillations in transport measurements on Cd 3 As 2 nanowires, revealing these exotic surface states. Nature Communications doi: 10.1038/ncomms10769 Authors: Li-Xian Wang, Cai-Zhen Li, Da-Peng Yu, Zhi-Min Liao… Continue reading Aharonov–Bohm oscillations in Dirac semimetal Cd3As2 nanowires
Stability of ipilimumab in its original vial after opening allows its use for at least 4 weeks and facilitates pooling of residues
Publication date: May 2016 Source:European Journal of Cancer, Volume 58 Author(s): Pascale Bardo-Brouard, Victoire Vieillard, Tala Shekarian, Aurélien Marabelle, Alain Astier, Muriel Paul PurposeWell-documented stability data of monoclonal antibodies are generally missing. That is why we studied the physicochemical and biological stability of undiluted ipilimumab (IPI) in glass vial (5 mg/ml) over 28 d after… Continue reading Stability of ipilimumab in its original vial after opening allows its use for at least 4 weeks and facilitates pooling of residues
The exposure of the Great Barrier Reef to ocean acidification
Article As the oceans become acidic, corals reefs are threatened, generating a need to understand the driving forces controlling the chemical state of the Great Barrier Reef. Here, the authors show a greater spatial variability than previously reported, created by the interaction of reef processes and ocean circulation. Nature Communications doi: 10.1038/ncomms10732 Authors: Mathieu Mongin,… Continue reading The exposure of the Great Barrier Reef to ocean acidification
Immunohistochemical subtypes predict survival in metastatic breast cancer receiving high-dose chemotherapy with autologous haematopoietic stem cell transplantation
Publication date: April 2016 Source:European Journal of Cancer, Volume 57 Author(s): Laurys Boudin, Christian Chabannon, Patrick Sfumato, Renaud Sabatier, François Bertucci, Carole Tarpin, Magali Provansal, Gilles Houvenaegel, Eric Lambaudie, Agnes Tallet, Michel Resbeut, Emmanuelle Charafe-Jauffret, Boris Calmels, Claude Lemarie, Jean-Marie Boher, Jean-Marc Extra, Patrice Viens, Anthony Gonçalves IntroductionThe objective of this study was to evaluate… Continue reading Immunohistochemical subtypes predict survival in metastatic breast cancer receiving high-dose chemotherapy with au... περισσότερα »
Thirty years of phase I radiochemotherapy trials: Latest development
Publication date: May 2016 Source:European Journal of Cancer, Volume 58 Author(s): Romain Rivoirard, Alexis Vallard, Julien Langrand-Escure, Majed Ben Mrad, Guoping Wang, Jean-Baptiste Guy, Peng Diao, Alexandre Dubanchet, Eric Deutsch, Chloe Rancoule, Nicolas Magne Radiochemotherapy is undergoing a complete expansion. Currently, possibilities of treatment combination are skyrocketting, with different anticancer and targeted molecules, different radiotherapy… Continue reading Thirty years of phase I radiochemotherapy trials: Latest development
Flow invariant droplet formation for stable parallel microreactors
Article Microfluidic reactors offer cheap and simple solutions for nanoparticle synthesis, but suffer from the variation in particle size due to flow fluctuations. Riche et al . fabricate a device that is robust over a large range of flow rates and enables consistent particle synthesis in parallel operation. Nature Communications doi: 10.1038/ncomms10780 Authors: Carson T.… Continue reading Flow invariant droplet formation for stable parallel microreactors
Fear of large carnivores causes a trophic cascade
Article Top predators may indirectly influence ecological processes through fear-induced behavioural changes in their prey. By experimentally manipulating this ‘landscape of fear’, Suraci et al . show that fear of large carnivores in a mesopredator can cause cascading effects down the food web that benefit its prey. Nature Communications doi: 10.1038/ncomms10698 Authors: Justin P. Suraci,… Continue reading Fear of large carnivores causes a trophic cascade
Anaesthesia and global health initiatives for children in a low-resource environment.
AlexAndros SfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026Πριν από 8 δευτερόλεπτα
Purpose of review: As the United Nations moves from Millennium Development Goals to Sustainable Development Goals, we find ourselves with the opportunity to influence the priority of global health initiatives. Previously, the global health community has failed to recognise the importance of access to safe, affordable surgery and developing the necessary specialities that support it as most of the funding focus had been on primary healthcare and infectious diseases. Recent findings: Now the WHO is publishing guidelines to safe surgery and the Lancet Commission on Global Surgery has b... περισσότερα »
Patients prone for postoperative delirium: preoperative assessment, perioperative prophylaxis, postoperative treatment.
AlexAndros SfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026Πριν από 8 δευτερόλεπτα
Purpose of review: The aim of this study was to review current literature on identification of patients at risk for postoperative delirium (POD) and to summarize recent findings on prophylaxis and treatment. Recent findings: Age and preoperative cognitive impairment are among the most important risk factors of POD. POD is the result of a complex interplay of predisposing and precipitating factors. Thus, both prophylaxis and treatment require multicomponent intervention programs. No single medication to prevent or treat POD is available. Avoiding too deep anesthesia, avoiding addition... περισσότερα »
Forthcoming Meetings
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 16 δευτερόλεπτα
from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1TyjNm7 via IFTTT
Analysis of IgE binding patterns to house dust mite allergens in scabies-endemic communities: insights for both diseases
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 16 δευτερόλεπτα
from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1QbBmnF via IFTTT
Severe asthma, shrimp allergy and impact of maternal fatty acid status on their children
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 16 δευτερόλεπτα
from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1TyjN5Q via IFTTT
Middle-ear and inner-ear contribution to bone bonduction in chinchilla: The development of Carhart’s notch
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 16 δευτερόλεπτα
Publication date: Available online 24 February 2016 Source:Hearing Research Author(s): David Chhan, Peter Bowers, Melissa L. McKinnon, John J. Rosowski While the cochlea is considered the primary site of the auditory response to bone conduction (BC) stimulation, the paths by which vibratory energy applied to the skull (or other structures) reaches the inner ear are […]
Acetylation of lysine 109 modulates pregnane X receptor DNA binding and transcriptional activity
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 16 δευτερόλεπτα
Publication date: Available online 23 February 2016 Source:Biochimica et Biophysica Acta (BBA) – Gene Regulatory Mechanisms Author(s): Danielle Pasquel, Aneta Doricakova, Hao Li, Sandhya Kortagere, Matthew D. Krasowski, Arunima Biswas, William G. Walton, Matthew R. Redinbo, Zdenek Dvorak, Sridhar Mani Pregnane X receptor (PXR) is a major transcriptional regulator of xenobiotic metabolism and transport pathways […]
Neurofibromatosis 2 (NF2) controls the invasiveness of glioblastoma thorough YAP-dependent expression of CYR61/CCN1 and miR-296-3p
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 16 δευτερόλεπτα
Publication date: Available online 24 February 2016 Source:Biochimica et Biophysica Acta (BBA) – Gene Regulatory Mechanisms Author(s): Hong Lee, Su Jin Hwang, Hye Ree Kim, Chang Hoon Shin, Kyung Hee Choi, Je-Gun Joung, Hyeon Ho Kim Glioblastoma multiforme (GBM) is the most common and aggressive type of primary brain tumor derived from non-neuronal glial cells. […]
Diabetic ketoacidosis presenting with atypical hemolytic uremic syndrome associated with a variant of complement factor B in an adult: a case report
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 16 δευτερόλεπτα
Background: Non-Shiga toxin-associated hemolytic uremic syndrome is known to be caused by dysregulation of the alternative complement pathway. Infections, drugs, pregnancy, bone marrow transplantation, malignancy, and autoimmune disorders have all been reported to trigger episodes of atypical hemolytic uremic syndrome. To the best of our knowledge, there have been no previous reports of an association […]
Child development: Know what’s ahead
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 16 δευτερόλεπτα
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Cosmetic surgery: What to know beforehand
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 16 δευτερόλεπτα
Considering cosmetic surgery? Here’s help deciding whether surgery is right for you. from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1TF37uI via IFTTT
Comment Zika virus and microcephaly in Brazil: a scientific agenda
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 16 δευτερόλεπτα
Since 1981, the Brazilian population has had dengue fever epidemics and all control efforts have been unsuccessful.1 In 2014, chikungunya fever was reported for the first time in the country.2 In 2015, the occurrence of Zika virus was also reported,3 along with an increase of microcephaly and brain damage in newborn babies.4,5 The mosquito Aedes […]
Child development: Know what’s ahead
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 33 δευτερόλεπτα
from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1TF37uL via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
Cosmetic surgery: What to know beforehand
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 33 δευτερόλεπτα
Considering cosmetic surgery? Here’s help deciding whether surgery is right for you. from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1TF37uI via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
Anaesthesia and global health initiatives for children in a low-resource environment.
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 33 δευτερόλεπτα
Purpose of review: As the United Nations moves from Millennium Development Goals to Sustainable Development Goals, we find ourselves with the opportunity to influence the priority of global health initiatives. Previously, the global health community has failed to recognise the importance of access to safe, affordable surgery and developing the necessary specialities that support it […]
Patients prone for postoperative delirium: preoperative assessment, perioperative prophylaxis, postoperative treatment.
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 33 δευτερόλεπτα
Purpose of review: The aim of this study was to review current literature on identification of patients at risk for postoperative delirium (POD) and to summarize recent findings on prophylaxis and treatment. Recent findings: Age and preoperative cognitive impairment are among the most important risk factors of POD. POD is the result of a complex […]
Use of organic acids for prevention and removal of Bacillus subtilis biofilms on food contact surfaces
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 33 δευτερόλεπτα
The efficacies of organic acid (citric, malic, and gallic acids) treatments at 1% and 2% concentrations on prevention and removal of Bacillus subtilis biofilms were investigated in this study. The analyses were conducted on microtitration plates and stainless steel coupons. The biofilm removal activities of these organic acids were compared with chlorine on both surfaces. […]
Use of organic acids for prevention and removal of Bacillus subtilis biofilms on food contact surfaces
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 33 δευτερόλεπτα
The efficacies of organic acid (citric, malic, and gallic acids) treatments at 1% and 2% concentrations on prevention and removal of Bacillus subtilis biofilms were investigated in this study. The analyses were conducted on microtitration plates and stainless steel coupons. The biofilm removal activities of these organic acids were compared with chlorine on both surfaces. […]
Fatal infantile mitochondrial encephalomyopathy, hypertrophic cardiomyopathy and optic atrophy associated with a homozygous OPA1 mutation
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 33 δευτερόλεπτα
Journal of Medical Genetics from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1Ou33G4 via IFTTT
Editorial.
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 33 δευτερόλεπτα
No abstract available from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1Qbxfb6 via IFTTT
Factors affecting choice of repair in Mohs micrographic surgery for non-melanoma skin cancer of the head
Abstract Background/Objectives In Mohs micrographic surgery (MMS) the dermatologist serves as surgeon, pathologist and reconstructive surgeon. Analysis of the factors that play a part in determining defect size and closure type may result in better patient outcomes. The objective was to identify factors contributing to the defect size and closure method employed in MMS. Methods Retrospective analysis of all MMS performed for non-melanoma skin cancers (NMSC) of the head at the Skin and Cancer Foundation Australia, Westmead, between 1 January and 31 December 2007. Results Tumor s...περισσότερα »
Middle-ear and inner-ear contribution to bone bonduction in chinchilla: The development of Carhart’s notch
[image: S03785955.gif] Publication date: Available online 24 February 2016 *Source:*Hearing Research Author(s): David Chhan, Peter Bowers, Melissa L. McKinnon, John J. Rosowski While the cochlea is considered the primary site of the auditory response to bone conduction (BC) stimulation, the paths by which vibratory energy applied to the skull (or other structures) reaches the inner ear are a matter of continued investigation. We present acoustical measurements of sound in the inner ear that separate out the components of BC stimulation that stimulate the inner ear via ossicular motio...περισσότερα »
Middle-ear and inner-ear contribution to bone bonduction in chinchilla: The development of Carhart’s notch
[image: S03785955.gif] Publication date: Available online 24 February 2016 *Source:*Hearing Research Author(s): David Chhan, Peter Bowers, Melissa L. McKinnon, John J. Rosowski While the cochlea is considered the primary site of the auditory response to bone conduction (BC) stimulation, the paths by which vibratory energy applied to the skull (or other structures) reaches the inner ear are a matter of continued investigation. We present acoustical measurements of sound in the inner ear that separate out the components of BC stimulation that stimulate the inner ear via ossicular motio...περισσότερα »
Middle-ear and inner-ear contribution to bone bonduction in chinchilla: The development of Carhart’s notch
[image: S03785955.gif] Publication date: Available online 24 February 2016 *Source:*Hearing Research Author(s): David Chhan, Peter Bowers, Melissa L. McKinnon, John J. Rosowski While the cochlea is considered the primary site of the auditory response to bone conduction (BC) stimulation, the paths by which vibratory energy applied to the skull (or other structures) reaches the inner ear are a matter of continued investigation. We present acoustical measurements of sound in the inner ear that separate out the components of BC stimulation that stimulate the inner ear via ossicular motio...περισσότερα »
Middle-ear and inner-ear contribution to bone bonduction in chinchilla: The development of Carhart’s notch
Publication date: Available online 24 February 2016 *Source:*Hearing Research Author(s): David Chhan, Peter Bowers, Melissa L. McKinnon, John J. Rosowski While the cochlea is considered the primary site of the auditory response to bone conduction (BC) stimulation, the paths by which vibratory energy applied to the skull (or other structures) reaches the inner ear are a matter of continued investigation. We present acoustical measurements of sound in the inner ear that separate out the components of BC stimulation that stimulate the inner ear via ossicular motion (compression of the wal... περισσότερα »
Middle-ear and inner-ear contribution to bone bonduction in chinchilla: The development of Carhart’s notch
Publication date: Available online 24 February 2016 *Source:*Hearing Research Author(s): David Chhan, Peter Bowers, Melissa L. McKinnon, John J. Rosowski While the cochlea is considered the primary site of the auditory response to bone conduction (BC) stimulation, the paths by which vibratory energy applied to the skull (or other structures) reaches the inner ear are a matter of continued investigation. We present acoustical measurements of sound in the inner ear that separate out the components of BC stimulation that stimulate the inner ear via ossicular motion (compression of the wal... περισσότερα »
Sinus Balloon Dilation as Treatment for Acute Sphenoid Sinusitis with Impaired Vision for a Child
This paper is about sinus balloon dilatation in treatment of acute left sphenoid sinusitis with left impaired vision in a child. Balloon catheter dilatation (BCD) of the sinus ostia is a new technique. It has been shown to be a minimally invasive technique to manage chronic sinusitis. However, this method is rarely used in the treatment of acute sinusitis. So far, we know of no reported cases of sinus balloon dilatation in treatment of this case, especially for children. from Cases via ola Kala on Inoreader http://ift.tt/1LFz0vt via IFTTT
Determination of the appropriate sizes of oropharyngeal airways in adults: correlation with external facial measurements: A randomised crossover study.
BACKGROUND: Two external facial measurements have been recommended as reference criteria for estimating appropriate oropharyngeal airway sizes: the distances between the maxillary incisors to the angle of the mandible, and that from the corner of the mouth to the angle of the mandible. OBJECTIVE: To compare the two guidelines and to determine the optimal external facial measurements for the selection of an appropriately sized airway in adults. DESIGN: Randomised crossover study. SETTING: Operating theatres in a university hospital. PATIENTS: A total of 113 patients requiring trachea...περισσότερα »
Dispatcher-assisted compression-only cardiopulmonary resuscitation provides best quality cardiopulmonary resuscitation by laypersons: A randomised controlled single-blinded manikin trial.
BACKGROUND: High-quality cardiopulmonary resuscitation (CPR) by laypersons is a key determinant of both outcome and survival for out-of-hospital cardiac arrest. Dispatcher-assisted CPR (telephone-CPR, T-CPR) increases the frequency and correctness of bystander-CPR but results in prolonged time to first chest compressions. However, it remains unclear whether instructions for rescue ventilation and/or chest compressions should be recommended for dispatcher-assisted CPR. OBJECTIVE: The aim of this study was to evaluate both principles of T-CPR with respect to CPR quality. DESIGN: Rando...περισσότερα »
Acetylation of lysine 109 modulates pregnane X receptor DNA binding and transcriptional activity
Publication date: Available online 23 February 2016 *Source:*Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms Author(s): Danielle Pasquel, Aneta Doricakova, Hao Li, Sandhya Kortagere, Matthew D. Krasowski, Arunima Biswas, William G. Walton, Matthew R. Redinbo, Zdenek Dvorak, Sridhar Mani Pregnane X receptor (PXR) is a major transcriptional regulator of xenobiotic metabolism and transport pathways in the liver and intestines, which are critical for protecting organisms against potentially harmful xenobiotic and endobiotic compounds. Inadvertent activation of drug meta...περισσότερα »
Neurofibromatosis 2 (NF2) controls the invasiveness of glioblastoma thorough YAP-dependent expression of CYR61/CCN1 and miR-296-3p
[image: alertIcon.gif] Publication date: Available online 24 February 2016 *Source:*Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms Author(s): Hong Lee, Su Jin Hwang, Hye Ree Kim, Chang Hoon Shin, Kyung Hee Choi, Je-Gun Joung, Hyeon Ho Kim Glioblastoma multiforme (GBM) is the most common and aggressive type of primary brain tumor derived from non-neuronal glial cells. Neurofibromatosis 2 (NF2) protein, also termed as merlin, is a well-known tumor suppressor; however, the molecular mechanism underlying this effect has not yet been fully defined. To investigate the rol...περισσότερα »
Diabetic ketoacidosis presenting with atypical hemolytic uremic syndrome associated with a variant of complement factor B in an adult: a case report
[image: sfx_links?getImage] Background: Non-Shiga toxin-associated hemolytic uremic syndrome is known to be caused by dysregulation of the alternative complement pathway. Infections, drugs, pregnancy, bone marrow transplantation, malignancy, and autoimmune disorders have all been reported to trigger episodes of atypical hemolytic uremic syndrome. To the best of our knowledge, there have been no previous reports of an association between diabetic ketoacidosis and atypical hemolytic uremic syndrome.Case presentationWe describe a case of a 26-year-old Spanish man who presented with di... περισσότερα »
Kidney-specific knockout of Sav1 in the mouse promotes hyper-proliferation of renal tubular epithelium through suppression of the Hippo pathway
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 1 ώρα
Abstract Previously, we have reported that Salvador homolog 1 (SAV1), a component of the Hippo pathway, is significantly downregulated in high-grade clear cell renal cell carcinoma (ccRCC) due to 14q copy number loss, and that this downregulation contributes to the proliferation and survival of renal tubular epithelial cells through activation of Yes-associated protein 1 (YAP1), […]
Localized soft elasticity in liquid crystal elastomers
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 1 ώρα
Article Ruggedized stretchable electronic devices motivate the development of globally stretchable yet locally stiff materials. Here, Ware et al . programme the self-organization of liquid crystal elastomers to yield stretchable materials of homogenous composition but with spatial variation in mechanical properties. Nature Communications doi: 10.1038/ncomms10781 Authors: Taylor H. Ware, John S. Biggins, Andreas F. Shick, […]
Editorial.
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 1 ώρα
No abstract available from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1Qbxfb6 via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/21eRYFz via IFTTT
Aharonov–Bohm oscillations in Dirac semimetal Cd3As2 nanowires
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 1 ώρα
Article Dirac semimetals are a three-dimensional analogue of graphene that can support massless Dirac fermions in their bulk and Fermi-arc surface states. Here, the authors observe Aharonov–Bohm oscillations in transport measurements on Cd 3 As 2 nanowires, revealing these exotic surface states. Nature Communications doi: 10.1038/ncomms10769 Authors: Li-Xian Wang, Cai-Zhen Li, Da-Peng Yu, Zhi-Min Liao […]
Stability of ipilimumab in its original vial after opening allows its use for at least 4 weeks and facilitates pooling of residues
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 1 ώρα
Publication date: May 2016 Source:European Journal of Cancer, Volume 58 Author(s): Pascale Bardo-Brouard, Victoire Vieillard, Tala Shekarian, Aurélien Marabelle, Alain Astier, Muriel Paul PurposeWell-documented stability data of monoclonal antibodies are generally missing. That is why we studied the physicochemical and biological stability of undiluted ipilimumab (IPI) in glass vial (5 mg/ml) over 28 d after […]
The exposure of the Great Barrier Reef to ocean acidification
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 1 ώρα
Article As the oceans become acidic, corals reefs are threatened, generating a need to understand the driving forces controlling the chemical state of the Great Barrier Reef. Here, the authors show a greater spatial variability than previously reported, created by the interaction of reef processes and ocean circulation. Nature Communications doi: 10.1038/ncomms10732 Authors: Mathieu Mongin, […]
Immunohistochemical subtypes predict survival in metastatic breast cancer receiving high-dose chemotherapy with autologous haematopoietic stem cell transplantation
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 1 ώρα
Publication date: April 2016 Source:European Journal of Cancer, Volume 57 Author(s): Laurys Boudin, Christian Chabannon, Patrick Sfumato, Renaud Sabatier, François Bertucci, Carole Tarpin, Magali Provansal, Gilles Houvenaegel, Eric Lambaudie, Agnes Tallet, Michel Resbeut, Emmanuelle Charafe-Jauffret, Boris Calmels, Claude Lemarie, Jean-Marie Boher, Jean-Marc Extra, Patrice Viens, Anthony Gonçalves IntroductionThe objective of this study was to evaluate […]
Flow invariant droplet formation for stable parallel microreactors
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 1 ώρα
Article Microfluidic reactors offer cheap and simple solutions for nanoparticle synthesis, but suffer from the variation in particle size due to flow fluctuations. Riche et al . fabricate a device that is robust over a large range of flow rates and enables consistent particle synthesis in parallel operation. Nature Communications doi: 10.1038/ncomms10780 Authors: Carson T. […]
Thirty years of phase I radiochemotherapy trials: Latest development
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 1 ώρα
Publication date: May 2016 Source:European Journal of Cancer, Volume 58 Author(s): Romain Rivoirard, Alexis Vallard, Julien Langrand-Escure, Majed Ben Mrad, Guoping Wang, Jean-Baptiste Guy, Peng Diao, Alexandre Dubanchet, Eric Deutsch, Chloe Rancoule, Nicolas Magne Radiochemotherapy is undergoing a complete expansion. Currently, possibilities of treatment combination are skyrocketting, with different anticancer and targeted molecules, different radiotherapy […]
Fear of large carnivores causes a trophic cascade
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 1 ώρα
Article Top predators may indirectly influence ecological processes through fear-induced behavioural changes in their prey. By experimentally manipulating this ‘landscape of fear’, Suraci et al . show that fear of large carnivores in a mesopredator can cause cascading effects down the food web that benefit its prey. Nature Communications doi: 10.1038/ncomms10698 Authors: Justin P. Suraci, […]
Stability of ipilimumab in its original vial after opening allows its use for at least 4 weeks and facilitates pooling of residues
Publication date: May 2016 Source:European Journal of Cancer, Volume 58 Author(s): Pascale Bardo-Brouard, Victoire Vieillard, Tala Shekarian, Aurélien Marabelle, Alain Astier, Muriel Paul PurposeWell-documented stability data of monoclonal antibodies are generally missing. That is why we studied the physicochemical and biological stability of undiluted ipilimumab (IPI) in glass vial (5 mg/ml) over 28 d after… Continue reading Stability of ipilimumab in its original vial after opening allows its use for at least 4 weeks and facilitates pooling of residues
Immunohistochemical subtypes predict survival in metastatic breast cancer receiving high-dose chemotherapy with autologous haematopoietic stem cell transplantation
Publication date: April 2016 Source:European Journal of Cancer, Volume 57 Author(s): Laurys Boudin, Christian Chabannon, Patrick Sfumato, Renaud Sabatier, François Bertucci, Carole Tarpin, Magali Provansal, Gilles Houvenaegel, Eric Lambaudie, Agnes Tallet, Michel Resbeut, Emmanuelle Charafe-Jauffret, Boris Calmels, Claude Lemarie, Jean-Marie Boher, Jean-Marc Extra, Patrice Viens, Anthony Gonçalves IntroductionThe objective of this study was to evaluate… Continue reading Immunohistochemical subtypes predict survival in metastatic breast cancer receiving high-dose chemotherapy with au... περισσότερα »
Thirty years of phase I radiochemotherapy trials: Latest development
Publication date: May 2016 Source:European Journal of Cancer, Volume 58 Author(s): Romain Rivoirard, Alexis Vallard, Julien Langrand-Escure, Majed Ben Mrad, Guoping Wang, Jean-Baptiste Guy, Peng Diao, Alexandre Dubanchet, Eric Deutsch, Chloe Rancoule, Nicolas Magne Radiochemotherapy is undergoing a complete expansion. Currently, possibilities of treatment combination are skyrocketting, with different anticancer and targeted molecules, different radiotherapy… Continue reading Thirty years of phase I radiochemotherapy trials: Latest development
Oncogene status as a diagnostic tool in ocular and cutaneous melanoma
Publication date: April 2016 Source:European Journal of Cancer, Volume 57 Author(s): Klaus G. Griewank, Bastian Schilling, Simone L. Scholz, Claudia H. Metz, Elisabeth Livingstone, Antje Sucker, Inga Möller, Henning Reis, Cindy Franklin, Ioana Cosgarea, Uwe Hillen, Klaus-Peter Steuhl, Dirk Schadendorf, Henrike Westekemper, Lisa Zimmer The majority of human tumours can be easily and correctly diagnosed… Continue reading Oncogene status as a diagnostic tool in ocular and cutaneous melanoma
A new prognostic model using absolute lymphocyte count in patients with primary central nervous system lymphoma
Publication date: April 2016 Source:European Journal of Cancer, Volume 57 Author(s): Ji Eun Jang, Yu Ri Kim, Soo-Jeong Kim, Hyunsoo Cho, Haerim Chung, Jung Yeon Lee, Hyunsung Park, Yundeok Kim, June-Won Cheong, Yoo Hong Min, Jin Seok Kim PurposePrimary central nervous system lymphoma (PCNSL) is an aggressive and rare extranodal non-Hodgkin lymphoma (NHL). Absolute lymphocyte… Continue reading A new prognostic model using absolute lymphocyte count in patients with primary central nervous system lymphoma
Is cancer a good way to die? A population-based survey among middle-aged and older adults in the United Kingdom
Publication date: March 2016 Source:European Journal of Cancer, Volume 56 Author(s): Charlotte Vrinten, Jane Wardle ObjectivesDespite improved outcomes, cancer remains widely feared, often because of its association with a long and protracted death as opposed to the quick death that people associate with that other common cause of adult mortality: heart disease. Former editor-in-chief of… Continue reading Is cancer a good way to die? A population-based survey among middle-aged and older adults in the United Kingdom
Determination of the appropriate sizes of oropharyngeal airways in adults: correlation with external facial measurements: A randomised crossover study.
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
BACKGROUND: Two external facial measurements have been recommended as reference criteria for estimating appropriate oropharyngeal airway sizes: the distances between the maxillary incisors to the angle of the mandible, and that from the corner of the mouth to the angle of the mandible. OBJECTIVE: To compare the two guidelines and to determine the optimal external […]
Dispatcher-assisted compression-only cardiopulmonary resuscitation provides best quality cardiopulmonary resuscitation by laypersons: A randomised controlled single-blinded manikin trial.
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
BACKGROUND: High-quality cardiopulmonary resuscitation (CPR) by laypersons is a key determinant of both outcome and survival for out-of-hospital cardiac arrest. Dispatcher-assisted CPR (telephone-CPR, T-CPR) increases the frequency and correctness of bystander-CPR but results in prolonged time to first chest compressions. However, it remains unclear whether instructions for rescue ventilation and/or chest compressions should be recommended […]
Molecular Impairment Mechanisms of Novel OPA1 Mutations Predicted by Molecular Modeling in Patients With Autosomal Dominant Optic Atrophy and Auditory Neuropathy Spectrum Disorder.
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Hypothesis: Different missense mutations of the optic atrophy 1 gene (OPA1) identified in optic atrophy patients with auditory neuropathy spectrum disorder (ANSD) induce functional impairment through different molecular mechanisms. Background: OPA1 is the gene responsible for autosomal dominant optic atrophy (ADOA), but some of its mutations are also associated with ANSD. OPA1 is a member […]
Diffusion Tensor Imaging Tractography of the Facial Nerve in Patients With Cerebellopontine Angle Tumors.
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Objective: To demonstrate the utility of diffusion tensor imaging (DTI) fiber tractography of the facial nerve in patients with cerebellopontine angle (CPA) tumors. Study Design: Prospective. Setting: Tertiary referral center. Patients: DTI technique was established in 113 patients without tumors and in 28 patients with CPA tumors. Subsequently, DTI results were compared with intraoperative findings […]
Repeated Postoperative Follow-up Diffusion-Weighted Magnetic Resonance Imaging to Detect Residual or Recurrent Cholesteatoma.
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Objective: In our institution, follow-up diffusion-weighted imaging (DWI) after cholesteatoma surgery is performed at least twice. The aim of this study was to determine the yield of the second follow-up DWI (D-W MRI-2) in patients in whom the first postoperative DWI (D-W MRI-1) was negative for residual or recurrent cholesteatoma. Study Design: A retrospective analysis. […]
Lack of Evidence for Nonotosclerotic Stapes Fixation in Human Temporal Bone Histopathology.
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Hypothesis: Nonotosclerotic stapes fixation does not represent a significant cause of stapes ankylosis in patients undergoing stapedectomy; the vast majority have otosclerosis. Background: Nonotosclerotic stapes fixation has been proposed as the diagnosis in 30 to 40% of patients undergoing stapedectomy (after excluding rare congenital, systemic, and syndromic causes of stapes fixation and tympanosclerosis). This finding […]
The first decade of estrogen receptor cistromics in breast cancer
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
The advent of genome-wide transcription factor profiling has revolutionized the field of breast cancer research. Estrogen receptor alpha (ERα), the major drug target in hormone receptor-positive breast cancer, has been known as a key transcriptional regulator in tumor progression for over 30 years. Even though this function of ERα is heavily exploited and widely accepted […]
Vitamin D deficiency impairs skeletal muscle function in a smoking mouse model
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Chronic obstructive pulmonary disease (COPD) is associated with skeletal muscle dysfunction. Vitamin D plays an important role in muscle strength and performance in healthy individuals. In COPD, vitamin D deficiency is highly prevalent but its role in skeletal muscle dysfunction is unclear. We examined the time-course effect of vitamin D deficiency on limb muscle function […]
Palmitoylated PrRP analog decreases body weight in rats with DIO but not in ZDF rats
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Anorexigenic neuropeptides produced and acting in the brain have the potential to decrease food intake and ameliorate obesity but are ineffective after peripheral application, owing to a limited ability to cross the blood-brain barrier. We have designed lipidized analogs of prolactin-releasing peptide (PrRP), which is involved in energy balance regulation as demonstrated by obesity phenotypes […]
Middle/Late Givetian ostracod assemblages from the Aisne quarry (Durbuy area, Ardenne, Belgium). Biostratigraphic and palaeoecological implications
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Publication date: Available online 23 February 2016 Source:Annales de Paléontologie Author(s): Sébastien Maillet, Taniel Danelian, Jean-Georges Casier The ostracod fauna of the Aisne quarry section (south-eastern border of the Dinant Synclinorium, Ardenne, Belgium) is studied here in order to complete the Middle Devonian record of these micro-crustaceans on the Ardennean platform, allowing thus biostratigraphic correlations […]
Magnetic resonance analysis of malignant transformation in recurrent glioma
Background Patients with low-grade glioma (LGG) have a relatively long survival, and a balance is often struck between treating the tumor and impacting quality of life. While lesions may remain stable for many years, they may also undergo malignant transformation (MT) at the time of recurrence and require more aggressive intervention. Here we report on a state-of-the-art multiparametric MRI study of patients with recurrent LGG. Methods One hundred and eleven patients previously diagnosed with LGG were scanned at either 1.5 T or 3 T MR at the time of recurrence. Volumetric and i... περισσότερα »
Systematic review with meta-analysis: diagnostic overlap of microscopic colitis and functional bowel disorders
Summary Background Microscopic colitis shares certain common clinical manifestations with functional bowel disorders, especially diarrhoea-dominant irritable bowel syndrome (IBS) and functional diarrhoea. However, the exact relationship between microscopic colitis and functional bowel disorders has not been systematically assessed. Aim To conduct a systematic review and meta-analysis on the diagnostic overlap between functional bowel disorders and microscopic colitis. Methods We searched MEDLINE, EMBASE and SCOPUS databases, as well as the abstract books of the major gastroente... περισσότερα »
Review article: bile acid diarrhoea – pathogenesis, diagnosis and management
Summary Background Bile acid diarrhoea results from imbalances in the homoeostasis of bile acids in the enterohepatic circulation. It can be a consequence of ileal disease/dysfunction, associated with other GI pathology or can be idiopathic. Aims To summarise the different types of bile acid diarrhoea and discuss the currently available diagnostic methods and treatments. Results Bile acid diarrhoea is found in up to 40% of patients diagnosed as having functional diarrhoea/IBS-D, and in up to 80% of patients who have undergone ileal resection. It is likely under-diagnosed and un... περισσότερα »
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Table of Contents
[image: inntim_web_banner_decided.gif] from #Allergy-Immunology via alexandrossfakianakis on Inoreader http://ift.tt/1LFrX5K via IFTTT
Strong TCR-mediated signals suppress integrated stress responses induced by KDELR1 deficiency in naive T cells
KDEL receptor 1 (KDELR1) regulates integrated stress responses (ISR) to promote naive T-cell survival *in vivo*. In a mouse line having nonfunctional KDELR1, T-Red (naive T-cell reduced) mice, polyclonal naive T cells show excessive ISR and eventually undergo apoptosis. However, breeding T-Red mice with TCR-transgenic mice bearing relatively high TCR affinity rescued the T-Red phenotype, implying a link between ISR-induced apoptosis and TCR-mediated signaling. Here, we showed that strong TCR stimulation reduces ISR in naive T cells. In mice lacking functional KDELR1, surviving nai...περισσότερα »
Quantification of adipose transfer viability using a novel, bioluminescent murine model
Publication date: Available online 23 February 2016 *Source:*Journal of Plastic, Reconstructive & Aesthetic Surgery Author(s): A.A. Gassman, K.K. Kao, J.P. Bradley, J.C. Lee Fat grafting has highly variable long-term results. Research efforts to improve the reliability of fat grafting are limited by inefficient methods to evaluate fat engraftment. In this work, we describe a novel animal model for quantitative evaluation of fat grafting using in-vivo bioluminescence of adipocytes from luciferase expressing mice. Subcutaneous adipose tissue from GFP and luciferase-expressing FVB mice ... περισσότερα »
Opposing roles of LTB4 and PGE2 in regulating the inflammasome-dependent scorpion venom-induced mortality
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 2 ώρες
Article Scorpion venom causes thousands of deaths worldwide. Here the authors show that the envenomation acts via prostaglandin E2 leading to inflammasome activation and lung pathology, counterbalanced by inflammation-limiting LTB4, and that COX inhibitors or exogenous LTB4 rescue the venom-induced mortality in mice. Nature Communications doi: 10.1038/ncomms10760 Authors: Karina F. Zoccal, Carlos A. Sorgi, Juliana […]
The strategy for management of tympanic membrane retractions
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 2 ώρες
The strategy for management of tympanic membrane retractions: I have read with great interest the article by Lee et al. [1], who raised an important issue on tympanic membrane retractions. The authors concluded that attic cholesteatoma may present as a tiny retraction of the pars flaccida; therefore, attic retractions should be observed closely in spite […]
Systematic review with meta-analysis: diagnostic overlap of microscopic colitis and functional bowel disorders
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 2 ώρες
Summary Background Microscopic colitis shares certain common clinical manifestations with functional bowel disorders, especially diarrhoea-dominant irritable bowel syndrome (IBS) and functional diarrhoea. However, the exact relationship between microscopic colitis and functional bowel disorders has not been systematically assessed. Aim To conduct a systematic review and meta-analysis on the diagnostic overlap between functional bowel disorders and […]
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