Allergic Contact Dermatitis After Bone-anchored Hearing Aid Surgery.
Allergic Contact Dermatitis After Bone-anchored Hearing Aid Surgery.:
Severe Maxillofacial Injuries
Our Treatment Approaches in Severe Maxillofacial Injuries Occurring After Failed Suicide Attempts Using Long-Barreled Guns.: Maxillofacial traumas with long-barreled guns may sometimes cause catastrophic results by means of smashing in facial structures. In these patients, reconstruction strategies of both fragmented/lost soft and hard tissues still remain controversial. In their clinic, the authors treated 5 patients with severely injured face after failed suicide attempt between 2008 and 2013. In this study, the authors aimed to present their clinical experiences on these severely... περισσότερα »
Primary Abbe Flap for Median Cleft Lip Deformity: New Trends on an Old Concept.
Primary Abbe Flap for Median Cleft Lip Deformity: New Trends on an Old Concept.: Objective: The authors present our experience using primary Abbe flaps for median cleft lip. Methods: The records of 9 patients who underwent primary Abbe flaps were reviewed for indications, operative details, and complications. Flap design is discussed, including the "W" method to facilitate columellar reconstruction. Maxillomandibular fixation was not used. Results: From 2004 to 2015, 9 patients with median cleft lip received primary Abbe flaps. Mean age was 10.2 +/- 6.2 months. Lobar holoprosencephal... περισσότερα »
Risk Factors for Life-Threatening Complications of Maxillofacial Space Infection.
Risk Factors for Life-Threatening Complications of Maxillofacial Space Infection.: The purpose of this study was to review the clinical features of maxillofacial space infection (MSI), and to identify the potential risk factors predisposing to life-threatening complications. A retrospective review of the medical charts of patients with MSI treated at Peking University School and Hospital of Stomatology from August 2008 to September 2013 was conducted. A total of 127 patients [75 men (59.1%) and 52 women (40.9%); mean age, 45.39 +/- 21.18 years, with a range of 1-85 years] formed the... περισσότερα »
Real Time Navigation-Assisted Orbital Wall Reconstruction in Blowout Fractures.
Real Time Navigation-Assisted Orbital Wall Reconstruction in Blowout Fractures.: Background: Limitation in performing restoration of orbital structures is the narrow, deep, and dark surgical field, which makes it difficult to view the operative site directly. To avoid perioperative complications from this limitation, the authors have evaluated the usefulness of computer-assisted navigation techniques in surgical treatment of blowout fracture. Methods: Total 37 patients (14 medial orbital wall fractures and 23 inferior orbital wall fractures) with facial deformities had surgical trea... περισσότερα »
Otoplasty Outcomes With Different Suture Materials in a Rabbit Model.
Otoplasty Outcomes With Different Suture Materials in a Rabbit Model.: Otoplasty is a commonly performed procedure to correct prominent ears. Many different otoplasty techniques have been described but there is no gold standard technique. As well, many different suture materials are used in otoplasty but studies directly comparing different sutures materials are lacking. An otoplasty outcome study with Nylon and Mersilene (2 of the most commonly used sutures in otoplasty) sutures was conducted using a rabbit model. Each rabbit ear was randomized to receive a Mustarde-type horizontal ... περισσότερα »
Brows Asymmetry Correction With the Direct Approach: Myth or Reality?.
Brows Asymmetry Correction With the Direct Approach: Myth or Reality?.: Objectives: The current article is aimed to test the effectiveness of direct and indirect brow lifting to correct brows asymmetry. Methods: Fifty patients treated with direct brow lift between January of 2011 and January of 2013 were investigated. All patients were men and treated under local anesthesia. In all patients, the brow lifting was associated with an upper blepharoplasty. The amount of brow elevation produced was assessed by comparison of the preoperative and at 1-year postoperative vertical distances b... περισσότερα »
Trancutaneous Versus Intraoral Approach to Isolated Zygomatic Arch Fractures: A Comparison of Two Techniques.
Trancutaneous Versus Intraoral Approach to Isolated Zygomatic Arch Fractures: A Comparison of Two Techniques.: Zygomatic arch fractures are caused by a vector force orthogonal to the bone segment that causes the collapse of the arch through depression of the bone fragments. Reduction of isolated zygomatic arch fractures are usually only of esthetic interest, with the exception of those cases where the fracture causes an impingement with the underlying mandibular coronoid process, causing limitation of mandibular movements. Reduction is usually performed with an extraoral approach, m... περισσότερα »
Treatment of Maxillary Glandular Odontogenic Cyst Involving the Same Place of Previously Treated Traumatic Bone Cyst.
Treatment of Maxillary Glandular Odontogenic Cyst Involving the Same Place of Previously Treated Traumatic Bone Cyst.: Glandular odontogenic cyst is a rare developmental odontogenic cysts of the jaws having an aggressive behavior. The most common site of occurrence is the anterior mandible, and it is widely seen in middle-aged people. It is suggested that trauma could be a precipitating factor for its occurrence. This article presents the diagnosis and treatment of a case of glandular odontogenic cyst at anterior maxilla that occurred at the same localization of a traumatic bone cyst... περισσότερα »
Cephalometric Assessment of Upper Airway Effects on Craniofacial Morphology.
Cephalometric Assessment of Upper Airway Effects on Craniofacial Morphology.: To investigate craniofacial growth deformities in children with upper airway obstruction, this controlled study was performed. Cephalometry is used as a screening test for anatomic abnormalities in patients with obstructive sleep apnea syndrome. Therefore, the current work selected this method to investigate the effect of upper airway obstruction on craniofacial morphology. Patients with upper airway obstruction (104) were compared with 71 controls. Patients with upper airway compromise had mandibular hypop...περισσότερα »
Schwannoma With Cystic Changes in the Pterygomandibular Space.
Schwannoma With Cystic Changes in the Pterygomandibular Space.: Schwannomas are tumors that arise from Schwann cells. Although schwannomas can occur almost anywhere in the body where nerve cells are present, they rarely occur in the head and neck region, including the oral and maxillofacial region. Cystic changes in schwannomas are extremely rare. This report is on a case of schwannoma with cystic changes that occurred in the pterygomandibular space. A 46-year-old woman presented with a complaint of limited mouth opening and pain on the left side of the mandible for 3 months. On pano... περισσότερα »
The Auricular Cartilage in Secondary and Tertiary Rhinoplasties
The Auricular Cartilage in 197 Secondary and Tertiary Rhinoplasties. by Pascali, Michele; Gentile, Pietro; Di Pasquali, Camilla; Bocchini, Ilaria; Cervelli, Valerio via Journal of Craniofacial Surgery - Published Ahead-of-Print Background: The purpose of this study was to describe and evaluate the efficacy of the use of auricular cartilage to treat aesthetic and functional deformities of patients who underwent secondary rhinoplasty o tertiary. Methods: From July 2005 to July 2014, 197 patients (144 women and 53 men) underwent rhinoplasty with the use of cartilage grafts. A total of 1... περισσότερα »
Facial Fractures
Epidemiological Profile of Facial Fractures and Their Relationship With Clinical-Epidemiological Variables Abstract The objective of this study was to identify the epidemiological profile of facial fractures and to associate with clinical-epidemiological variables. An epidemiological survey was conducted in which data retrieved from the records of patients with facial fractures were analyzed. Pearson [chi]2 test, Student t-test, one-way analysis of variance, Bonferroni post-hoc test, and logistic regression were used for statistical analysis, adopting a level of significance of 5%. T... περισσότερα »
The antifibrinolytic drug tranexamic acid (TXA) is effective in reducing blood loss and transfusion requirements
The Efficacy and Safety of Tranexamic Acid in Cranio-Maxillofacial and Plastic Surgery.: The antifibrinolytic drug tranexamic acid (TXA) is effective in reducing blood loss and transfusion requirements in other fields of elective surgery and its use is emerging in a number of plastic surgical subspecialties. This systematic review and meta-analysis evaluates the current evidence for the efficacy and safety of TXA in craniomaxillofacial, head and neck, breast, aesthetic, burns, and reconstructive microsurgery. We searched PubMed, EMBASE, Medline, The Cochrane Database of Systematic R...περισσότερα »
Volatile phytochemicals
Formic and Acetic Acids in Degradation Products of Plant Volatiles Elicit Olfactory and Behavioral Responses from an Insect Vector by George, J., Robbins, P. S., Alessandro, R. T., Stelinski, L. L., Lapointe, S. L. via Chemical Senses Volatile phytochemicals play a role in orientation by phytophagous insects. We studied antennal and behavioral responses of the Asian citrus psyllid, *Diaphorina citri*, vector of the citrus greening disease pathogen. Little or no response to citrus leaf volatiles was detected by electroantennography. Glass cartridges prepared with β-ocimene or citral pr... περισσότερα »
Multiportal combined transnasal transoral transpharyngeal endoscopic approach for selected skull base cancers
Alexandros G. SfakianakisστοHead,Neck,Brain,Cervical Spine and Esophageal Cancers by Alexandros G. SfakianakisΠριν από 5 δευτερόλεπτα
Multiportal combined transnasal transoral transpharyngeal endoscopic approach for selected skull base cancers: Background Minimally invasive endoscopic endonasal approaches to the ventral skull base have evolved considerably over the past several years. However, where there is a lateral extension of tumors as far as the parapharyngeal spaces with inferior extension below the level of the soft palate, limitations remain for an exclusive transnasal approach. Methods A combined endoscopic-assisted transnasal-transoral-transpharyngeal multiportal approach was performed to resect selecte...περισσότερα »
Intensity-modulated radiotherapy or volumetric-modulated arc therapy in patients with head and neck cancer: Focus on salivary glands dosimetry
Alexandros G. SfakianakisστοHead,Neck,Brain,Cervical Spine and Esophageal Cancers by Alexandros G. SfakianakisΠριν από 5 δευτερόλεπτα
Intensity-modulated radiotherapy or volumetric-modulated arc therapy in patients with head and neck cancer: Focus on salivary glands dosimetry: Abstract Background Despite radiotherapy (RT) technical improvements, high salivary dysfunction rates are still reported in patients with head and neck squamous cell carcinoma (HNSCC). The purpose of the present study was to report salivary glands dosimetry with volumetric-modulated arc therapy (VMAT) and intensity-modulated RT (IMRT). Methods Dosimetry of consecutive patients receiving IMRT or VMAT for proven HNSCC between 2007 and 2013 wer...περισσότερα »
The establishment of normal olfactory function
How Many and Which Odor Identification Items Are Needed to Establish Normal Olfactory Function? by Lötsch, J., Ultsch, A., Hummel, T. via Chemical Senses The establishment of normal olfactory function by means of a simple and reliable test is one method that could minimize olfactory test procedures in the clinic. This retrospective study analyzed the identification of 16 odors by 613 subjects (aged 18–96 years, 266 men) as a part of a complex olfactory test battery by which 183, 251, and 179 subjects were diagnosed with anosmia, hyposmia, or normosmia, respectively. Cinnamon was iden... περισσότερα »
Children with early cochlear implants
Long-term functional and behavioral-emotional outcomes in children with early cochlear implants: Parental testimonies via International Journal of Pediatric Otorhinolaryngology Publication date: Available online 8 February 2016 *Source:*International Journal of Pediatric Otorhinolaryngology Author(s): Mina Park, Seung Ha Oh, Sun O. Chang, Chong Sun Kim, Jun Ho Lee Objectives1) To assess the long-term effects of cochlear implantation (CI) on speech perception and school life, and 2) to evaluate behavioral and emotional development, including social skills, post-implantation.MethodsWe tel... περισσότερα »
The natural course of congenital nasal pyriform aperture stenosis
The natural course of congenital nasal pyriform aperture stenosis: Objectives/Hypothesis Patients with congenital nasal pyriform aperture stenosis (CNPAS) may become less symptomatic with age. Therefore, we aimed to develop a growth curve of the pyriform aperture so that a more comprehensive plan can be designed for CNPAS patients who show little response to conservative treatment. Study Design A single-institution study, retrospective review of CNPAS patients during the period November 1997 to December 2014. Methods We measured the distances between the bilateral nasal processes of ... περισσότερα »
Dysgenetic polycystic disease of the minor and submandibular salivary glands
Dysgenetic polycystic disease of the minor and submandibular salivary glands: Abstract Background Dysgenetic polycystic salivary gland disease is a rare pathology. No case of minor salivary gland involvement has been reported in the literature. Methods A female patient presented with bilateral tumors of the parotid glands, bilateral submandibular gland enlargement, and multiple cystic lesions of the oral mucosa. MRI of the neck was performed along with fine-needle aspiration (FNA) of the parotid tumors and excisional biopsy of an oral lesion. Results Imaging and FNA findings of the ... περισσότερα »
Multiportal combined transnasal transoral transpharyngeal endoscopic approach for selected skull base cancers
Multiportal combined transnasal transoral transpharyngeal endoscopic approach for selected skull base cancers: Background Minimally invasive endoscopic endonasal approaches to the ventral skull base have evolved considerably over the past several years. However, where there is a lateral extension of tumors as far as the parapharyngeal spaces with inferior extension below the level of the soft palate, limitations remain for an exclusive transnasal approach. Methods A combined endoscopic-assisted transnasal-transoral-transpharyngeal multiportal approach was performed to resect selecte...περισσότερα »
Intensity-modulated radiotherapy or volumetric-modulated arc therapy in patients with head and neck cancer: Focus on salivary glands dosimetry
Intensity-modulated radiotherapy or volumetric-modulated arc therapy in patients with head and neck cancer: Focus on salivary glands dosimetry: Abstract Background Despite radiotherapy (RT) technical improvements, high salivary dysfunction rates are still reported in patients with head and neck squamous cell carcinoma (HNSCC). The purpose of the present study was to report salivary glands dosimetry with volumetric-modulated arc therapy (VMAT) and intensity-modulated RT (IMRT). Methods Dosimetry of consecutive patients receiving IMRT or VMAT for proven HNSCC between 2007 and 2013 wer...περισσότερα »
Carbon ion radiotherapy for locally advanced adenoid cystic carcinoma of the tongue base
Evaluation of the safety and efficacy of carbon ion radiotherapy for locally advanced adenoid cystic carcinoma of the tongue base: Abstract Background Most cases of adenoid cystic carcinoma (ACC) of the tongue base are radioresistant, and are diagnosed in the advanced stage. Therefore, we evaluated the safety and efficacy of carbon ion radiotherapy (C-ion RT) for locally advanced ACC of the tongue base. Methods Eighteen patients with ACC of the tongue base were treated with C-ion RT between May 2002 and April 2014. Seventeen patients had T4a disease and 1 patient had T2 disease befo...περισσότερα »
BRAF V600E detection in cytological thyroid samples: A key component of the decision tree for surgical treatment of papillary thyroid carcinoma
BRAF V600E detection in cytological thyroid samples: A key component of the decision tree for surgical treatment of papillary thyroid carcinoma: Abstract Background Whether preoperative knowledge of the BRAF mutation status would help to determine the extent of surgery for thyroid nodules is still under investigation. Methods We developed a method to state the V600E mutation before surgery on fine-needle aspiration (FNA) stained smears checked to contain tumor cells. We evaluated the interest of the preoperative assessment of the mutation for surgical strategy of nodules, diagnosed ...περισσότερα »
Evaluation of the safety and efficacy of carbon ion radiotherapy for locally advanced adenoid cystic carcinoma of the tongue base
Alexandros G. SfakianakisστοHead,Neck,Brain,Cervical Spine and Esophageal Cancers by Alexandros G. SfakianakisΠριν από 10 δευτερόλεπτα
Evaluation of the safety and efficacy of carbon ion radiotherapy for locally advanced adenoid cystic carcinoma of the tongue base: Abstract Background Most cases of adenoid cystic carcinoma (ACC) of the tongue base are radioresistant, and are diagnosed in the advanced stage. Therefore, we evaluated the safety and efficacy of carbon ion radiotherapy (C-ion RT) for locally advanced ACC of the tongue base. Methods Eighteen patients with ACC of the tongue base were treated with C-ion RT between May 2002 and April 2014. Seventeen patients had T4a disease and 1 patient had T2 disease befo...περισσότερα »
BRAF V600E detection in cytological thyroid samples: A key component of the decision tree for surgical treatment of papillary thyroid carcinoma
Alexandros G. SfakianakisστοHead,Neck,Brain,Cervical Spine and Esophageal Cancers by Alexandros G. SfakianakisΠριν από 11 δευτερόλεπτα
BRAF V600E detection in cytological thyroid samples: A key component of the decision tree for surgical treatment of papillary thyroid carcinoma: Abstract Background Whether preoperative knowledge of the BRAF mutation status would help to determine the extent of surgery for thyroid nodules is still under investigation. Methods We developed a method to state the V600E mutation before surgery on fine-needle aspiration (FNA) stained smears checked to contain tumor cells. We evaluated the interest of the preoperative assessment of the mutation for surgical strategy of nodules, diagnosed ...περισσότερα »
Squamous cell cancer of the nasal cavity: New insights and implications for diagnosis and treatment
Alexandros G. SfakianakisστοHead,Neck,Brain,Cervical Spine and Esophageal Cancers by Alexandros G. SfakianakisΠριν από 11 δευτερόλεπτα
Squamous cell cancer of the nasal cavity: New insights and implications for diagnosis and treatment: Abstract Background Squamous cell carcinoma (SCC) of the nasal cavity is a rare malignancy and often analyzed in heterogeneous studies with other tumors of the nose or the paranasal sinuses. The purpose of this study was to evaluate distinct risk factors, tumor characteristics, outcome predictors, and the prevalence of human papillomavirus (HPV) in SCC of the nasal cavity. Methods We conducted a retrospective study of 39 patients treated at a single quaternary medical care and cancer... περισσότερα »
Squamous cell cancer of the nasal cavity: New insights and implications for diagnosis and treatment
Squamous cell cancer of the nasal cavity: New insights and implications for diagnosis and treatment: Abstract Background Squamous cell carcinoma (SCC) of the nasal cavity is a rare malignancy and often analyzed in heterogeneous studies with other tumors of the nose or the paranasal sinuses. The purpose of this study was to evaluate distinct risk factors, tumor characteristics, outcome predictors, and the prevalence of human papillomavirus (HPV) in SCC of the nasal cavity. Methods We conducted a retrospective study of 39 patients treated at a single quaternary medical care and cancer... περισσότερα »
Modified endoscopic transnasal-transmaxillary-transpterygoid approach to parapharyngeal space tumor resection
Modified endoscopic transnasal-transmaxillary-transpterygoid approach to parapharyngeal space tumor resection: ABSTRACT Background Conventional approaches for removing parapharyngeal space tumors require a cervical skin incision and resection of soft tissues between the skin and parapharyngeal space. The surgical visual field for this conventional approach is limited. Methods To decrease invasiveness during removal of benign parapharyngeal space tumors and to enhance the visual field, we devised a new approach called the modified endoscopic transnasal-transmaxillary-transpterygoid a... περισσότερα »
Sensorineural Tinnitus: Its Pathology and Probable Therapies
Sensorineural Tinnitus: Its Pathology and Probable Therapies: Tinnitus is not a single disease but a group of different diseases with different pathologies and therefore different treatments. Regarding tinnitus as a single disease is hampering progress in understanding of the pathophysiology of tinnitus and perhaps, more importantly, it is a serious obstacle in development of effective treatments for tinnitus. Subjective tinnitus is a phantom sound that takes many different forms and has similarities with chronic neuropathic pain. The pathology may be in the cochlea, in the auditory... περισσότερα »
Euthyroid Levothyroxine-Treated Women Have Slightly Lower Resting Energy Expenditure but the Same Body Composition as Women on TSH-Suppressive Levothyroxine Therapy and Healthy Controls
Euthyroid Levothyroxine-Treated Women Have Slightly Lower Resting Energy Expenditure but the Same Body Composition as Women on TSH-Suppressive Levothyroxine Therapy and Healthy Controls: Clinical Thyroidology Feb 2016, Vol. 28, No. 2: 30-33. [image: Free first page]
Differentiated Thyroid Cancer: is There a Need for Radioiodine Ablation in Low Risk Patients?
Alexandros G. SfakianakisστοHead,Neck,Brain,Cervical Spine and Esophageal Cancers by Alexandros G. SfakianakisΠριν από 12 δευτερόλεπτα
Differentiated Thyroid Cancer: is There a Need for Radioiodine Ablation in Low Risk Patients?: *Condition*: Low Risk Differentiated Thyroid Cancer *Interventions*: Drug: rhTSH stimulation; Drug: I131; Other: Follow up *Sponsor*: Gustave Roussy, Cancer Campus, Grand Paris Open-label randomized phase III trial, using a non-inferiority comparison design. After randomization,patients will receive either post-operative radioiodine ablation with an activity of 1.1 GBq (30 mCi) after stimulation by rhTSH, and then be followed-up (ablation group) or be followed-up (without posto... περισσότερα »
Phase III Trial Comparing Methotrexate and Cetuximab in First-line Treatment of Recurrent and/or Metastatic Squamous Cell Head and Neck Cancer
Alexandros G. SfakianakisστοHead,Neck,Brain,Cervical Spine and Esophageal Cancers by Alexandros G. SfakianakisΠριν από 14 δευτερόλεπτα
Phase III Trial Comparing Methotrexate and Cetuximab in First-line Treatment of Recurrent and/or Metastatic Squamous Cell Head and Neck Cancer: *Condition*: Head Neck Cancer Squamous Cell Recurrent *Interventions*: Drug: Cetuximab; Drug: Methotrexate *Sponsors*: Gustave Roussy, Cancer Campus, Grand Paris; National Cancer Institute, France; Ligue contre le cancer, France; Merck Serono International SA To test whether cetuximab improves efficacy/tolerance as compared to methotrexate in first line treatment of unfit patients ³ 70 years old with recurrent and /or metast... περισσότερα »
Efficacy of Radium 223 in Radioactive Iodine Refractory Bone Metastases From Differentiated Thyroid Cancer
Alexandros G. SfakianakisστοHead,Neck,Brain,Cervical Spine and Esophageal Cancers by Alexandros G. SfakianakisΠριν από 14 δευτερόλεπτα
Efficacy of Radium 223 in Radioactive Iodine Refractory Bone Metastases From Differentiated Thyroid Cancer: *Condition*: Thyroid Cancer *Intervention*: Radiation: Radium 223 *Sponsor*: Gustave Roussy, Cancer Campus, Grand Paris The purpose of this Phase II single-arm study is to evaluate the efficacy of Radium-223 in treating bone lesions from differentiated thyroid cancer that are I-131 refractory. Based on the results of the phase III trial, the protocol using an injection of Radium-223 activity of 50 kBq/kg b.w. given 6 times at 4 weeks interval will be applied. The end p... περισσότερα »
Skin/Soft Tissue Elasticity in Head and Neck Cancer Survivors With Lymphedema and Fibrosis
Alexandros G. SfakianakisστοHead,Neck,Brain,Cervical Spine and Esophageal Cancers by Alexandros G. SfakianakisΠριν από 17 δευτερόλεπτα
Skin/Soft Tissue Elasticity in Head and Neck Cancer Survivors With Lymphedema and Fibrosis: *Conditions*: Cancer Survivor; Head and Neck Carcinoma; Lymphedema-Related Fibrosis Adverse Event; No Evidence of Disease *Interventions*: Procedure: Medical Examination; Other: Questionnaire Administration; Procedure: Shear Wave Elastography *Sponsors*: Vanderbilt-Ingram Cancer Center; National Cancer Institute (NCI) This research trial studies skin/soft tissue elasticity in head and neck cancer survivors with lymphedema and fibrosis. Lymphedema and fibrosis is a common ... περισσότερα »
Meta-analysis identifies multiple loci associated with kidney function–related traits in east Asian populations
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 17 δευτερόλεπτα
Nature genetics from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1T9ZAEl via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
In Vivo Modulation of Nogo-B Attenuates Neointima Formation
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 17 δευτερόλεπτα
Molecular therapy : the journal of the American Society of Gene Therapy from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/20SA3kj via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
Familial adult onset hyperinsulinism due to an activating glucokinase mutation: Implications for pharmacological glucokinase activation
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 17 δευτερόλεπτα
Clinical endocrinology from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1T9ZAnQ via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
Changes in sexual risk behavior among MSM participating in a research cohort in coastal Kenya
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 17 δευτερόλεπτα
AIDS (London, England) from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/20SA33U via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
Role of angiotensin AT2 receptors and nitric oxide in the cardiopulmonary baroreflex control of renal sympathetic nerve activity in anaesthetised rats
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 17 δευτερόλεπτα
Journal of hypertension from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1T9ZyfL via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
Elucidating the molecular architecture of adaptation via evolve and resequence experiments
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 17 δευτερόλεπτα
Nature reviews. Genetics from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/20SA2Nx via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
Skin/Soft Tissue Elasticity in Head and Neck Cancer Survivors With Lymphedema and Fibrosis
Skin/Soft Tissue Elasticity in Head and Neck Cancer Survivors With Lymphedema and Fibrosis: *Conditions*: Cancer Survivor; Head and Neck Carcinoma; Lymphedema-Related Fibrosis Adverse Event; No Evidence of Disease *Interventions*: Procedure: Medical Examination; Other: Questionnaire Administration; Procedure: Shear Wave Elastography *Sponsors*: Vanderbilt-Ingram Cancer Center; National Cancer Institute (NCI) This research trial studies skin/soft tissue elasticity in head and neck cancer survivors with lymphedema and fibrosis. Lymphedema and fibrosis is a common ... περισσότερα »
IL-1β induced RXRα overexpression through activation of NF-κB signaling in gastric carcinoma
Publication date: March 2016 *Source:*Biomedicine & Pharmacotherapy, Volume 78 Author(s): Hong-Yue Ren, Gui-Li Huang, Wen-Ming Liu, Wei Zhang, Yu Liu, Guo-Qiang Su, Dong-Yan Shen BackgroundAbnormal expression of Retinoid X Receptor α (RXRα) seems to be a frequent incident in a variety of cancers. However, the expression pattern and the mechanisms in gastric carcinoma (GC) remain unclear.MethodsIn GC tissues and cell lines, the expression levels of RXRα mRNA and protein were detected by Q-PCR and Western blot, respectively; the localization of RXRα was evaluated by immunohistochemist... περισσότερα »
Mutation R273H confers p53 a stimulating effect on the IGF-1R-AKT pathway via miR-30a suppression in breast cancer
Publication date: March 2016 *Source:*Biomedicine & Pharmacotherapy, Volume 78 Author(s): Fangdong Guo, Hongshen Chen, Jian Chang, Lin Zhang p53 is the most highly mutated tumor suppressor in human malignancies. A wide array of p53 mutations has been revealed to play pivotal roles during cancer progression, which abolish anti-tumor functions of wild type p53 but also elicit tumorigenic effects by activating a diverse subset of downstream molecules. R273H mutation of p53 has been closely implicated in human cancer. Here we report miR-30a as a novel downstream target of p53 R273H muta... περισσότερα »
Influence of Esophageal Washout on Local Carcinoma Recurrence After Curative Resection
Alexandros G. SfakianakisστοHead,Neck,Brain,Cervical Spine and Esophageal Cancers by Alexandros G. SfakianakisΠριν από 19 δευτερόλεπτα
Influence of Esophageal Washout on Local Carcinoma Recurrence After Curative Resection: *Condition*: Esophageal Neoplasms *Intervention*: Drug: Betaisodona *Sponsor*: Technische Universität Dresden The LOCARE-Trial is an investigator initiated, randomized-controlled trial with two parallel arms (n=60 each) and investigates the influence of esophageal washout on long-term outcomes in patients undergoing elective esophageal resection for carcinoma. The primary endpoint is defined as local carcinoma recurrence. Secondary endpoints will be locoregional and distant recurrence,... περισσότερα »
The HABP2 G534E Variant Is Unlikely to Be Implicated in the Risk of Familial or Sporadic Nonmedullary Thyroid Cancer
Alexandros G. SfakianakisστοHead,Neck,Brain,Cervical Spine and Esophageal Cancers by Alexandros G. SfakianakisΠριν από 19 δευτερόλεπτα
Letter to the Editor: The HABP2 G534E Variant Is Unlikely to Be Implicated in the Risk of Familial or Sporadic Nonmedullary Thyroid Cancer: Clinical Thyroidology Feb 2016, Vol. 28, No. 2: 52-54.
Pregnancy Does Not Increase the Size of Papillary Thyroid Microcarcinomas
Alexandros G. SfakianakisστοHead,Neck,Brain,Cervical Spine and Esophageal Cancers by Alexandros G. SfakianakisΠριν από 23 δευτερόλεπτα
Pregnancy Does Not Increase the Size of Papillary Thyroid Microcarcinomas: Clinical Thyroidology Feb 2016, Vol. 28, No. 2: 39-40.
The Use of Genetics May Infer Causality in the Association of Body Composition with Thyroid Function
The Use of Genetics May Infer Causality in the Association of Body Composition with Thyroid Function: Clinical Thyroidology Feb 2016, Vol. 28, No. 2: 34-36. [image: Free first page]
The Linear Relationship Between Log TSH and Free T4
Analysis of a Large Population Establishes the Linear Relationship Between Log TSH and Free T4: Clinical Thyroidology Feb 2016, Vol. 28, No. 2: 45-47. [image: Free first page]
Some Dopaminergic Agents Do Not Alter the TSH-Lowering Effect of Metformin in Hypothyroidism
Some Dopaminergic Agents Do Not Alter the TSH-Lowering Effect of Metformin in Hypothyroidism: Clinical Thyroidology Feb 2016, Vol. 28, No. 2: 41-44. [image: Free first page]
Sustainability, Vol. 8, Pages 166: The Principle of Integration in International Sustainable Development Law (ISDL) with Reference to the Biological Weapons Convention (BWC)
The Biological Weapons Convention (BWC) does not explicitly refer to sustainable development despite the fact that other United Nations (UN) disarmament documents prescribe that international environmental law principles and sustainable development be considered among arms control agreements. This study's objective is to utilize the principle of integration's three components of environmental, economic, and social development, as found in the International Sustainable Development Law (ISDL) from the New Delhi Declaration (Delhi Declaration) of Principles of International Law Relat...περισσότερα »
Applied Sciences, Vol. 6, Pages 49: Dynamic Characterization of Cohesive Material Based on Wave Velocity Measurements
The paper presents a description of the dynamic properties of cohesive material, namely silty clays, obtained by using one of the applied seismology methods, the bender elements technique. The authors' aim was to present the dynamics of a porous medium, in particular an extremely important passage of seismic waves that travel through the bulk of a medium. Nowadays, the application of the bender element (BE) technique to measure, e.g., small strain shear stiffness of soils in the laboratory is well recognized, since it allows for reliable and relatively economical shear wave veloci... περισσότερα »
Salt depletion syndrome as the initial presentation of cystic fibrosis in a toddler with the rare p.Ala309Gly (A309G) CFTR variant
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Charakterisierung des laryngealen Adduktionsreflexes durch Stimulation mit Mikrotröpfchen-Impulsen (microdroplet impulse testing)
Charakterisierung des laryngealen Adduktionsreflexes durch Stimulation mit Mikrotröpfchen-Impulsen (microdroplet impulse testing): Laryngo-Rhino-Otol DOI: 10.1055/s-0041-111516 Hintergrund: Der Kehlkopf gilt als Kreuzungsstelle zwischen Atem- und Schluckwegen. Erfolgt die Nahrungsaufnahme, müssen durch geeignete Verschlussmechanismen die Atemwege unterhalb der Glottis sicher gegen ein Eindringen von Nahrungsbestandteilen geschützt werden. Als wesentlicher Verschlussmechanismus gilt der laryngeale Adduktionsreflex (LAR) mit einer frühen, vermutlich di- oder oligosynaptisch verschalt... περισσότερα »
Associação Brasileira de Otorrinolaringologia e Cirurgia Cérvico-Facial
*Editoriais* *A judicialização do ato médicoRoberto Augusto de Carvalho Campos, Rosmari Aparecida Elias Camargo, Luciano Rodrigues NevesBraz J Otorhinolaryngol. 2016;82:1-2Texto Completo - PDF* *Artigos originais* *Efeitos de tarefas cognitivas simultâneas no equilíbrio postural em indivíduos saudáveisBanu Mujdeci, Didem Turkyilmaz, Suha Yagcioglu, Songul AksoyBraz J Otorhinolaryngol. 2016;82:3-10Resumo - Texto Completo - PDF* *Análise morfológica do sistema vestibular de cobaias intoxicadas por organofosforadoLícia Assunção Cogo, Valdete Alves Valentins dos Santos Filha, Adriana d... περισσότερα »
Subtotal arytenoidectomy for the treatment of laryngeal stridor in multiple system atrophy: phonatory and swallowing results
Aritenoidectomia subtotal para o tratamento de estridor laríngeo na atrofia de múltiplos sistemas: resultados na fonação e deglutição [Livre artigo] via Brazilian Journal of Otorhinolaryngology Francesco Stomeo, Vittorio Rispoli, Mariachiara Sensi, Antonio Pastore, Nicola Malagutti, Stefano Pelucchi Braz J Otorhinolaryngol. 2016;82:116-20 Texto Completo - PDF Subtotal arytenoidectomy for the treatment of laryngeal stridor in multiple system atrophy: phonatory and swallowing results Francesco Stomeoa, Vittorio Rispolib, Mariachiara Sensib, Antonio Pastorea, Nicola Malaguttia, Stefano Pe... περισσότερα »
Giant sialolith of submandibular gland duct treated by excision and ductal repair
Sialolito gigante de ducto da glândula submandibular tratado por excisão e reparo ductal: relato de caso [Livre artigo] via Brazilian Journal of Otorhinolaryngology Thiago de Paula Oliveira, Isaac Nilton Fernandes Oliveira, Eduardo Carvalho Paes Pinheiro, Renata Caroline Ferreira Gomes, Pietro Mainenti Braz J Otorhinolaryngol. 2016;82:112-5 Texto Completo - PDF Giant sialolith of submandibular gland duct treated by excision and ductal repair: a case report Thiago de Paula Oliveiraa, Isaac Nilton Fernandes Oliveiraa, Eduardo Carvalho Paes Pinheiroa, Renata Caroline Ferreira Gomesa, Piet... περισσότερα »
Gestational rhinitis and rhinitis ‘‘during pregnancy’’
Rinite na gestação: revisão de literatura [Livre artigo] via Brazilian Journal of Otorhinolaryngology Fábio Azevedo Caparroz, Luciano Lobato Gregorio, Giuliano Bongiovanni, Suemy Cioffi Izu, Eduardo Macoto Kosugi Braz J Otorhinolaryngol. 2016;82:105-11 Resumo - Texto Completo - PDF Rhinitis and pregnancy: literature review Fábio Azevedo Caparroza, Luciano Lobato Gregorioa, Giuliano Bongiovannia, Suemy Cioffi Izua, Eduardo Macoto Kosugib a Programa de Pós-graduação em Medicina, Escola Paulista de Medicina, Universidade Federal de São Paulo (UNIFESP-EPM), São Paulo, SP, Brasil b Departame...περισσότερα »
Electromagnetic radiofrequency radiation
Zumbido e telefones celulares: o papel da radiação eletromagnética de radiofrequência [Livre artigo] via Brazilian Journal of Otorhinolaryngology Luisa Nascimento Medeiros, Tanit Ganz Sanchez Braz J Otorhinolaryngol. 2016;82:97-104 Resumo - Texto Completo - PDF Tinnitus and cell phones: the role of electromagnetic radiofrequency radiation Luisa Nascimento Medeirosa, Tanit Ganz Sanchezb a Departamento de Otorrinolaringologia, Faculdade de Medicina, Universidade de São Paulo (USP), São Paulo, SP, Brasil. Associação de Pesquisa Interdisciplinar e Divulgação do Zumbido, São Paulo, SP, Bras... περισσότερα »
Energy Modulated Photon Radiotherapy: A Monte Carlo Feasibility Study
A novel treatment modality termed energy modulated photon radiotherapy (EMXRT) was investigated. The first step of EMXRT was to determine beam energy for each gantry angle/anatomy configuration from a pool of photon energy beams (2 to 10 MV) with a newly developed energy selector. An inverse planning system using gradient search algorithm was then employed to optimize photon beam intensity of various beam energies based on presimulated Monte Carlo pencil beam dose distributions in patient anatomy. Finally, 3D dose distributions in six patients of different tumor sites were simulat...περισσότερα »
Participation and health care provision of statutory skin cancer screening in Germany – a secondary data analysis
Abstract Background In Germany, skin cancer screening was introduced nationwide in July 2008. From the age of 35 years, members of the statutory health insurance are eligible for screening every 2 years. Objective The aim of this study is to calculate the participation rates and the proportions of health care providers of statutory skin cancer screening in Germany on a population-based level. Methods Data were provided by a nationwide German statutory health insurance, approximately 6.1 million members, covering the years 2008/2009. Participation rates were calculated per yearl... περισσότερα »
‘Ring-within-a-ring’ appearance: morphological clue to topical steroid abuse in dermatophytosis
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Minimally invasive follicular thyroid carcinomas: prognostic factors
otolaryngologistsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.Alexandros,,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,tel : 00302841026182,00306932607174Πριν από 37 δευτερόλεπτα
Abstract Although minimally invasive follicular thyroid carcinoma (MI-FTC) is regarded as an indolent tumour, treatment strategies remain controversial. Our aim was to investigate the outcome for patients with MI-FTC and to identify prognostic parameters to facilitate adequate treatment and follow-up. This retrospective follow-up study involved all cases of MI-FTC operated at the Karolinska University Hospital […]
Antifungal therapies in murine infections by Candida kefyr
otolaryngologistsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.Alexandros,,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,tel : 00302841026182,00306932607174Πριν από 37 δευτερόλεπτα
Summary Candida kefyr is an emerging pathogen able to cause disseminated infection, especially in immunocompromised patients. Although guidelines for the treatment of invasive candidiasis have been published, no specific recommendations against C. kefyr are available. We determine the in vitro killing activity of amphotericin B (AMB), fluconazole (FLC) and caspofungin (CFG) as well as their […]
Modulatory effect of romantic love on value estimation and its neural mechanism.
otolaryngologistsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.Alexandros,,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,tel : 00302841026182,00306932607174Πριν από 37 δευτερόλεπτα
Any decision that is based upon personal preferences utilizes subjective values; however, for objectively equivalent items, whether romantic love modulates subjective value as well as the neural mechanism of this process remains unknown. In this functional MRI study, 30 items with equivalent value were first selected and assigned into three groups, and participants were trained […]
Randomized clinical trial of the influence of impression technique on the fabrication of cast metal posts
otolaryngologistsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.Alexandros,,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,tel : 00302841026182,00306932607174Πριν από 37 δευτερόλεπτα
Publication date: Available online 9 February 2016 Source:The Journal of Prosthetic Dentistry Author(s): Aline Pinheiro de Moraes, Victório Poletto Neto, Noéli Boscato, Tatiana Pereira-Cenci Statement of problemDirect and indirect techniques are used for intracanal impression and fabrication of cast metal posts. However, whether those techniques affect the accuracy of cast metal posts is unknown.PurposeThe purpose […]
Digital approach to planning computer-guided surgery and immediate provisionalization in a partially edentulous patient
otolaryngologistsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.Alexandros,,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,tel : 00302841026182,00306932607174Πριν από 37 δευτερόλεπτα
Publication date: Available online 9 February 2016 Source:The Journal of Prosthetic Dentistry Author(s): Sirikarn P. Arunyanak, Bryan T. Harris, Gerald T. Grant, Dean Morton, Wei-Shao Lin This report describes a digital approach for computer-guided surgery and immediate provisionalization in a partially edentulous patient. With diagnostic data obtained from cone-beam computed tomography and intraoral digital diagnostic […]
Outcome of zirconia partial fixed dental prostheses made by predoctoral dental students: A clinical retrospective study after 3 to 7 years of clinical service.
otolaryngologistsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.Alexandros,,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,tel : 00302841026182,00306932607174Πριν από 37 δευτερόλεπτα
Publication date: Available online 9 February 2016 Source:The Journal of Prosthetic Dentistry Author(s): Juha Pihlaja, Ritva Näpänkangas, Aune Raustia Statement of problemZirconia has an established role in fixed prosthodontics, especially for single crowns. Whether it is durable enough for fixed dental prostheses (FDPs) in the long term is yet unclear.PurposeThe purpose of this retrospective study […]
The Association of Socioeconomic Status With Subclinical Myocardial Damage, Incident Cardiovascular Events, and Mortality in the ARIC Study
The association between socioeconomic status (SES) and subclinical cardiovascular disease is not well understood. Using data from the Atherosclerosis Risk in Communities Study, we sought to evaluate the cross-sectional and prospective associations of SES, measured by annual income and educational level, with elevated high-sensitivity cardiac troponin T (hs-cTnT) concentrations (≥14 ng/L) using Poisson and multinomial logistic regressions, respectively. We used Cox proportional hazard models to compare the risks of coronary heart disease, heart failure, and mortality according to S...περισσότερα »
Death of former leader poses potential problems for Nepal – Reuters
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 41 δευτερόλεπτα
Reuters Death of former leader poses potential problems for Nepal Reuters KATHMANDU Former Prime Minister Sushil Koirala, a moderate figure in Nepal’s unsettled politics, died on Tuesday, presenting a potential hurdle in attempts to win greater rights for minorities in a new constitution. Koirala, 78, a senior figure in one … Former Nepal PM Sushil […]
The phenotype of migraine with unilateral cranial autonomic symptoms documents increased peripheral and central trigeminal sensitization. A case series of 757 patients
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 41 δευτερόλεπτα
Background Migraine with unilateral cranial autonomic symptoms (UAS) is a putative migraine endophenotype with convincing response to trigeminal-targeted treatments that still needs a thorough characterization. Objective The objective of this article is to carefully investigate the clinical phenotype of migraine with UAS in a large group of patients for more accurate migraine diagnoses, improved clinical […]
Identification of a highly immunogenic mouse breast cancer sub cell line, 4T1-S
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 41 δευτερόλεπτα
Abstract Cancer vaccines serve as a promising clinical immunotherapeutic strategy that help to trigger an effective and specific antitumor immune response compared to conventional therapies. However, poor immunogenicity of tumor cells remains a major obstacle for clinical application, and developing new methods to modify the immunogenicity of tumor cells may help to improve the clinical […]
Adipokine zinc-alpha-2-glycoprotein as a novel urinary biomarker presents earlier than microalbuminuria in diabetic nephropathy
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 41 δευτερόλεπτα
Objective To investigate the role of zinc-alpha-2-glycoprotein (ZAG) in the early stage of diabetic nephropathy, in patients with type 2 diabetes mellitus (T2DM). Methods This cross-sectional observational study recruited patients with longstanding T2DM and healthy control subjects. Patients with T2DM were further stratified based on their urine albumin–creatinine ratio (UACR) and estimated glomerular filtration rate […]
Serum cross-linked N-telopeptide of type I collagen for the diagnosis of bone metastases from solid tumours in the Chinese population: Meta-analysis
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 41 δευτερόλεπτα
Objective A meta-analysis to determine the diagnostic value of serum cross-linked N-telopeptide of type I collagen (NTx) for bone metastasis from solid tumours in the Chinese population. Methods Eligible case–control studies published up until 22 September 2014 were identified by searching the electronic literature databases PubMed®, Web of Science, China National Knowledge Infrastructure and Wanfang […]
Resistin: New serum marker for predicting severity of acute pancreatitis
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 41 δευτερόλεπτα
Objective To assess the effectiveness of resistin in predicting the severity of acute pancreatitis. Methods Patients with acute pancreatitis who presented at the Gastroenterology Clinic, Erzurum Education and Research Hospital, Turkey were enrolled in this prospective study. White blood cell (WBC), C-reactive protein (CRP) and resistin levels were measured on admission and at 24 h, […]
Prevalence rate and influencing factors of preoperative anxiety and depression in gastric cancer patients in China: Preliminary study
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 41 δευτερόλεπτα
Objectives To investigate the prevalence rate and influencing factors of preoperative anxiety and depression in patients with gastric cancer, in China. Methods Patients with gastric cancer who were diagnosed by gastroscopy and would accept laparoscopic surgery were eligible for the study. Each participant completed self-administered questionnaires, including the Hospital Anxiety and Depression Scale (HADS), Medical […]
Genetically lowered concentrations of circulating sRAGE might cause an increased risk of cancer: Meta-analysis using Mendelian randomization
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 41 δευτερόλεπτα
Objectives To undertake a systematic meta-analysis of all variants in the gene encoding receptor for advanced glycation end products (RAGE) to summarize their associations with cancer risk and changes in the levels of circulating soluble RAGE (sRAGE), with the aim of determining possible causality between circulating sRAGE and cancer risk. Methods Articles written in English […]
Role of angiotensin AT2 receptors and nitric oxide in the cardiopulmonary baroreflex control of renal sympathetic nerve activity in anaesthetised rats
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Inhibition of the histone demethylase JMJD2E by 3-substituted pyridine 2,4-dicarboxylates
Organic & biomolecular chemistry from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1TPuQI0 via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1K95TFt via IFTTT
Essential and dystonic voice tremor : Laryngoscopy evaluation protocol
Protocolo de avaliação por laringoscopia para diferenciar tremor vocal essencial e distônico [Livre artigo] via Brazilian Journal of Otorhinolaryngology Bruno Teixeira de Moraes, Noemi Grigoletto de Biase Braz J Otorhinolaryngol. 2016;82:88-96 Resumo - Texto Completo - PDF Laryngoscopy evaluation protocol for the differentiation of essential and dystonic voice tremor Bruno Teixeira de Moraesa, Noemi Grigoletto de Biaseb a Departamento de Otorrinolaringologia, Ciências da Saúde, Universidade Federal de São Paulo (UNIFESP), São Paulo, SP, Brasil. Departamento de Otorrinolaringologia, Uni... περισσότερα »
Suppurative labyrinthitis associated with otitis media
Labirintite associada à otite média: experiência de 26 anos [Livre artigo] via Brazilian Journal of Otorhinolaryngology André Souza de Albuquerque Maranhão, Valeria Romero Godofredo, Norma de Oliveira Penido Braz J Otorhinolaryngol. 2016;82:82-7 Resumo - Texto Completo - PDF Suppurative labyrinthitis associated with otitis media: 26 years’ experience André Souza de Albuquerque Maranhãoa, Valeria Romero Godofredob, Norma de Oliveira Penidoa a Departamento de Otorrinolaringologia, Escola Paulista de Medicina, Universidade Federal de São Paulo (EPM-UNIFESP), São Paulo, SP, Brasil. Departa... περισσότερα »
Newborn Hearing Screening
Unidade de Terapia Intensiva: resultados da Triagem Auditiva Neonatal [Livre artigo] via Brazilian Journal of Otorhinolaryngology Inaê Costa Rechia, Kátia Pase Liberalesso, Otília Valéria Melchiors Angst, Fernanda Donato Mahl, Michele Vargas Garcia, Eliara Pinto Vieira Biaggio Braz J Otorhinolaryngol. 2016;82:76-81 Resumo - Texto Completo - PDF Intensive care unit: results of the Newborn Hearing Screening Inaê Costa Rechiaa, Kátia Pase Liberalessob, Otília Valéria Melchiors Angstb, Fernanda Donato Mahla, Michele Vargas Garciac, Eliara Pinto Vieira Biaggioc a Distúrbios da Comunicação Hu... περισσότερα »
Hearing performance and voice acoustics of cochlear implanted children
Desempenho auditivo e acústica da voz de crianças com implante coclear [Livre artigo] via Brazilian Journal of Otorhinolaryngology Ana Cristina Coelho, Alcione Ghedino Brasolotto, Maria Cecília Bevilacqua, Adriane Lima Mortari Moret, Fayez Bahmad Júnior Braz J Otorhinolaryngol. 2016;82:70-5 Resumo - Texto Completo - PDF Hearing performance and voice acoustics of cochlear implanted children Ana Cristina Coelhoa, Alcione Ghedino Brasolottob, Maria Cecília Bevilacquab, Adriane Lima Mortari Moretb, Fayez Bahmad Júniorc a Hospital Universitário de Brasília (HUB/UnB), Brasília, DF, Brasil b D... περισσότερα »
Cancer, Hearing loss, Chemotherapy, Radiotherapy
Tratamento oncológico na determinação das alterações auditivas [Livre artigo] via Brazilian Journal of Otorhinolaryngology Priscila Feliciano de Oliveira, Camila Silva Oliveira, Joice Santos Andrade, Tamara Figueiredo do Carmo Santos, Aline Cabral de Oliveira-Barreto Braz J Otorhinolaryngol. 2016;82:65-9 Resumo - Texto Completo - PDF Cancer treatment in determination of hearing loss Priscila Feliciano de Oliveiraa, Camila Silva Oliveirab, Joice Santos Andradeb, Tamara Figueiredo do Carmo Santosb, Aline Cabral de Oliveira-Barretoc a Doutoranda pelo Programa Ciências da Saúde, Universida... περισσότερα »
Central auditory processing disorder in speech sound disorders
Influência do transtorno do processamento auditivo (central) no transtorno fonológico [Livre artigo] via Brazilian Journal of Otorhinolaryngology Tatiane Faria Barrozo, Luciana de Oliveira Pagan-Neves, Nadia Vilela, Renata Mota Mamede Carvallo, Haydée Fiszbein Wertzner Braz J Otorhinolaryngol. 2016;82:56-64 Resumo - Texto Completo - PDF The influence of (central) auditory processing disorder in speech sound disorders Tatiane Faria Barrozoa, Luciana de Oliveira Pagan-Nevesb, Nadia Vilelaa, Renata Mota Mamede Carvallob, Haydée Fiszbein Wertznerb a Programa de Ciências da Reabilitação, Fa... περισσότερα »
Surgical technique in rotation and nasal projection variation
Avaliação objetiva da técnica cirúrgica na variação da rotação e projeção nasal [Livre artigo] via Brazilian Journal of Otorhinolaryngology Marina Serrato Coelho Fagundes, Ana Tereza Moreira, Elizabeth Mila Tambara, Sérgio Bernardo Tenório, Rogério de Fraga, Rogerio Hamerschmidt Braz J Otorhinolaryngol. 2016;82:47-55 Resumo - Texto Completo - PDF Objective assessment of surgical technique in rotation and nasal projection variation Marina Serrato Coelho Fagundesa, Ana Tereza Moreiraa, Elizabeth Mila Tambara a, Sérgio Bernardo Tenórioa, Rogério de Fragaa, Rogerio Hamerschmidta a Clínica C... περισσότερα »
Acoustic analysis of oropharyngeal swallowing using Sonar Doppler
Análise acústica da deglutição orofaríngea utilizando Sonar Doppler [Livre artigo] via Brazilian Journal of Otorhinolaryngology Franciele Savaris Soria, Roberta Gonçalves da Silva, Ana Maria Furkim Braz J Otorhinolaryngol. 2016;82:39-46 Resumo - Texto Completo - PDF Acoustic analysis of oropharyngeal swallowing using Sonar Doppler Franciele Savaris Soriaa, Roberta Gonçalves da Silvab, Ana Maria Furkimc a Faculdade Assis Gurgacz, Cascavel, PR, Brasil b Universidade Estadual de São Paulo (UNESP), São Paulo, SP, Brasil c Universidade Federal de Santa Catarina (UFSC), Florianópolis, SC, Brasi... περισσότερα »
Molar tooth, Premolar tooth, Maxillary sinus, Dental root, Cone beam computed tomography
Relação entre doenças no seio maxilar e dentes hígidos [Livre artigo] via Brazilian Journal of Otorhinolaryngology Gina D. Roque-Torres, Laura Ricardina Ramirez-Sotelo, Sergio Lins de Azevedo Vaz, Solange Maria de Almeida de Bóscolo, Frab Norberto Bóscolo Braz J Otorhinolaryngol. 2016;82:33-8 Resumo - Texto Completo - PDF Association between maxillary sinus pathologies and healthy teeth Gina D. Roque-Torresa, Laura Ricardina Ramirez-Soteloa, Sergio Lins de Azevedo Vazb, Solange Maria de Almeida de Bóscoloa, Frab Norberto Bóscoloa a Departamento de Diagnóstico Oral, Faculdade de Odontolog...περισσότερα »
Issue Information – TOC
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 50 δευτερόλεπτα
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Elucidating the molecular architecture of adaptation via evolve and resequence experiments
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 50 δευτερόλεπτα
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15 April News
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 50 δευτερόλεπτα
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Biodegradable Nanoneedles for Localized Delivery of Nanoparticles in Vivo: Exploring the Biointerface
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 50 δευτερόλεπτα
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Planning digital artery perforators using color Doppler ultrasonography: a preliminary report
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 50 δευτερόλεπτα
Publication date: Available online 8 February 2016 Source:Journal of Plastic, Reconstructive & Aesthetic Surgery Author(s): Kosuke Shintani, Kiyohito Takamatsu, Takuya Uemura, Ema Onode, Mitsuhiro Okada, Kenichi Kazuki, Hiroaki Nakamura Digital artery perforator (DAP) flaps have been applied for the coverage of finger soft tissue defects. While an advantage of this method is that there is […]
Inhibition of the histone demethylase JMJD2E by 3-substituted pyridine 2,4-dicarboxylates
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 50 δευτερόλεπτα
Organic & biomolecular chemistry from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1TPuQI0 via IFTTT
Treatment of Asymptomatic Bacteriuria
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 50 δευτερόλεπτα
from #Infections via alexandrossfakianakis on Inoreader http://ift.tt/1KCdpsm via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1PyBm0D via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/23U6r8T via IFTTT
The phenotype of migraine with unilateral cranial autonomic symptoms documents increased peripheral and central trigeminal sensitization. A case series of 757 patients
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 50 δευτερόλεπτα
Background Migraine with unilateral cranial autonomic symptoms (UAS) is a putative migraine endophenotype with convincing response to trigeminal-targeted treatments that still needs a thorough characterization. Objective The objective of this article is to carefully investigate the clinical phenotype of migraine with UAS in a large group of patients for more accurate migraine diagnoses, improved clinical […]
In Vivo Modulation of Nogo-B Attenuates Neointima Formation
Molecular therapy : the journal of the American Society of Gene Therapy from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/20SA3kj via IFTTT
Issue Information – TOC
from #ORL-AlexandrosSfakianakis via simeraentaxei on Inoreader http://ift.tt/1T9Uacz via IFTTT
Familial adult onset hyperinsulinism due to an activating glucokinase mutation: Implications for pharmacological glucokinase activation
Clinical endocrinology from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1T9ZAnQ via IFTTT
Quadrivalent HPV vaccine effectiveness against high-grade cervical lesions by age at vaccination: A population-based study
Abstract Human papillomavirus (HPV) types 16/18, included in HPV vaccines, contribute to the majority of cervical cancer, and a substantial proportion of cervical intraepithelial neoplasia (CIN) grades 2/3 or worse (CIN2+/CIN3+) including adenocarcinoma in situ or worse. The aim of this study was to quantify the effect of quadrivalent HPV (qHPV) vaccination on incidence of… Continue reading Quadrivalent HPV vaccine effectiveness against high-grade cervical lesions by age at vaccination: A population-based study
Changes in sexual risk behavior among MSM participating in a research cohort in coastal Kenya
AIDS (London, England) from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/20SA33U via IFTTT
Role of angiotensin AT2 receptors and nitric oxide in the cardiopulmonary baroreflex control of renal sympathetic nerve activity in anaesthetised rats
Journal of hypertension from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1T9ZyfL via IFTTT
DESC1, a novel tumor suppressor, sensitizes cells to apoptosis by down-regulating the EGFR/AKT pathway in esophageal squamous cell carcinoma
Abstract Esophageal cancer is ranked as the eighth most common cancer and the sixth leading cause of cancer deaths worldwide. To identify candidate tumor suppressor genes related to esophageal squamous cell carcinoma (ESCC) development, a cDNA microarray analysis was performed using paired tumor and non-tumor tissue samples from ESCC patients. Differentially Expressed in Squamous cell… Continue reading DESC1, a novel tumor suppressor, sensitizes cells to apoptosis by down-regulating the EGFR/AKT pathway in esophageal squamous cell carcinoma
Telomere dysfunction and chromothripsis
Abstract Chromothripsis is a recently discovered form of genomic instability, characterized by tens to hundreds of clustered DNA rearrangements resulting from a single dramatic event. Telomere dysfunction has been suggested to play a role in the initiation of this phenomenon, which occurs in a large number of tumor entities. Here, we show that telomere attrition… Continue reading Telomere dysfunction and chromothripsis
Elucidating the molecular architecture of adaptation via evolve and resequence experiments
Nature reviews. Genetics from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/20SA2Nx via IFTTT
Cancer and frailty in older adults: a nested case-control study of the Mexican Health and Aging Study
Abstract Purpose Understanding how the convergence between chronic and complex diseases—such as cancer—and emerging conditions of older adults—such as frailty—takes place would help in halting the path that leads to disability in this age group. The objective of this manuscript is to describe the association between a past medical history of cancer and frailty in… Continue reading Cancer and frailty in older adults: a nested case-control study of the Mexican Health and Aging Study
Endoscopic sinus surgery dissection courses using a real simulator
Cursos de dissecção de cirurgia endoscópica nasossinusal em simulador real – os benefícios deste treinamento [Livre artigo] via Brazilian Journal of Otorhinolaryngology Bibiana Fortes, Leonardo Balsalobre, Raimar Weber, Raquel Stamm, Aldo Stamm, Fernando Oto, Nathália Coronel Braz J Otorhinolaryngol. 2016;82:26-32 Resumo - Texto Completo - PDF Endoscopic sinus surgery dissection courses using a real simulator: the benefits of this training Bibiana Fortesa, Leonardo Balsalobrea, Raimar Webera, Raquel Stamma, Aldo Stamma, Fernando Otoa, Nathália Coronela a Hospital Professor Edmundo Vasc...περισσότερα »
Bismuth subgallate had a negative influence on the healing process, delaying the rate of new vessel formation and optimal wound healing.
Estudo experimental sobre os efeitos do subgalato de bismuto no processo inflamatório e de angiogênese em mucosa bucal [Livre artigo] via Brazilian Journal of Otorhinolaryngology Eduardo Vieira Couto, Carlos Roberto Ballin, Claudia Paraguaçu Pupo Sampaio, Carlos Augusto Seije Maeda, Carlos Henrique Ballin, Camila Soares Dassi, Lilian Yukari Miura Braz J Otorhinolaryngol. 2016;82:17-25 Resumo - Texto Completo - PDF Estudo experimental sobre os efeitos do subgalato de bismuto no processo inflamatório e de angiogênese em mucosa bucal Eduardo Vieira Coutoa, Carlos Roberto Ballinb, Claudia ... περισσότερα »
Morphological analysis of the vestibular system
Braz J Otorhinolaryngol. 2016;82:11-6 Análise morfológica do sistema vestibular de cobaias intoxicadas por organofosforado [Livre artigo] via Brazilian Journal of Otorhinolaryngology Lícia Assunção Cogo, Valdete Alves Valentins dos Santos Filha, Adriana de Andrade Batista Murashima, Miguel Angelo Hyppolito, Aron Ferreira da Silveira Braz J Otorhinolaryngol. 2016;82:11-6 Resumo - Texto Completo - PDF Morphological analysis of the vestibular system of guinea pigs poisoned by organophosphate Lícia Assunção Cogoa, Valdete Alves Valentins dos Santos Filhab, Adriana de Andrade Batista Muras... περισσότερα »
Concurrent cognitive tasks on postural sway
Braz J Otorhinolaryngol. 2016;82:3-10 Efeitos de tarefas cognitivas simultâneas no equilíbrio postural em indivíduos saudáveis [Livre artigo] via Brazilian Journal of Otorhinolaryngology Banu Mujdeci, Didem Turkyilmaz, Suha Yagcioglu, Songul Aksoy Braz J Otorhinolaryngol. 2016;82:3-10 Resumo - Texto Completo - PDF The effects of concurrent cognitive tasks on postural sway in healthy subjects Banu Mujdecia, Didem Turkyilmazb, Suha Yagciogluc, Songul Aksoyb a Departamento de Audiologia, Faculdade de Ciências da Saúde, Yıldırım Beyazıt University, Ankara, Turquia b Departamento de Audiolog... περισσότερα »
Photodynamic therapy for premalignant and early stage head and neck tumors
Alexandros G. SfakianakisστοHead,Neck,Brain,Cervical Spine and Esophageal Cancers by Alexandros G. SfakianakisΠριν από 57 δευτερόλεπτα
Toxicities and early outcomes in a phase 1 trial of photodynamic therapy for premalignant and early stage head and neck tumors via ScienceDirect Publication: Oral Oncology Publication date: Available online 8 February 2016 *Source:*Oral Oncology Author(s): Peter H. Ahn, Harry Quon, Bert W. O’Malley, Gregory Weinstein, Ara Chalian, Kelly Malloy, Joshua H. Atkins, Thomas Sollecito, Martin Greenberg, Sally McNulty, Alexander Lin, Timothy C. Zhu, Jarod C. Finlay, Keith Cengel, Virginia Livolsi, Michael Feldman, Rosemarie Mick, Theresa M. Busch ObjectivesManagement of early superficial lesi...περισσότερα »
Photodynamic therapy for premalignant and early stage head and neck tumors
Toxicities and early outcomes in a phase 1 trial of via ScienceDirect Publication: Oral Oncology Publication date: Available online 8 February 2016 *Source:*Oral Oncology Author(s): Peter H. Ahn, Harry Quon, Bert W. O’Malley, Gregory Weinstein, Ara Chalian, Kelly Malloy, Joshua H. Atkins, Thomas Sollecito, Martin Greenberg, Sally McNulty, Alexander Lin, Timothy C. Zhu, Jarod C. Finlay, Keith Cengel, Virginia Livolsi, Michael Feldman, Rosemarie Mick, Theresa M. Busch ObjectivesManagement of early superficial lesions in the head and neck remains complex. We performed a phase 1 trial for... περισσότερα »
Common electronic origin of superconductivity in (Li,Fe)OHFeSe bulk superconductor and single-layer FeSe/SrTiO3 films
[image: ncomms10608-f1.jpg] Article The mechanism of high-temperature superconductivity in the iron-based materials remains not fully understood. Here, the authors report on ARPES measurements on an FeSe-based bulk superconductor, whose electronic properties are found to be similar to those of single-layer FeSe/STO films. Nature Communications doi: 10.1038/ncomms10608 Authors: Lin Zhao, Aiji Liang, Dongna Yuan, Yong Hu, Defa Liu, Jianwei Huang, Shaolong He, Bing Shen, Yu Xu, Xu Liu, Li Yu, Guodong Liu, Huaxue Zhou, Yulong Huang, Xiaoli Dong, Fang Zhou, Kai Liu, Zhongyi Lu, Zhongx... περισσότερα »
EXPOSURE TO POLYBROMINATED DIPHENYL ETHERS ASSOCIATES WITH HYPOTHYROIDISM
EXPOSURE TO POLYBROMINATED DIPHENYL ETHERS ASSOCIATES WITH HYPOTHYROIDISM *Oulhote Y1, Chevrier J1, Bouchard MF Exposure to Polybrominated Diphenyl Ethers (PBDEs) and Hypothyroidism in Canadian Women.* J Clin Endocrinol Metab. 2016 Feb;101(2):590-8. doi: 10.1210/jc.2015-2659. Epub 2015 Nov 25. Polybrominated diphenyl ethers (PBDEs) are used as flame retardants in a wide range of products, resulting in widespread human exposure. Epidemiological studies in some populations reported exposure to PBDEs and thyroid hormone levels but little epidemiological data are available among women ... περισσότερα »
Lysophosphatidic acid activates Arf6 to promote the mesenchymal malignancy of renal cancer
Article Acquisition of mesenchymal properties by cancer cells is a critical event for the development of malignancy. Here, the authors show that in renal cancer cells, lysosphosphatidic acid does not utilize the RhoA pathway but specifically activates the Arf6 mesenchymal pathway via its GPCRs and EFA6 to promote invasion, metastasis and drug resistance. Nature Communications doi: 10.1038/ncomms10656 Authors: Shigeru Hashimoto, Shuji Mikami, Hirokazu Sugino, Ayumu Yoshikawa, Ari Hashimoto, Yasuhito Onodera, Shotaro Furukawa, Haruka Handa, Tsukasa Oikawa, Yasunori Okada, Mototsugu... περισσότερα »
Single crystal functional oxides on silicon
Article Synthesis of single-crystal complex-oxide films directly on silicon is difficult due to differing interfacial chemistry. Here, the authors demonstrate room-temperature integration of single-crystal lead zirconate titanate on to silicon to act as a gate insulator in a field-effect transistor. Nature Communications doi: 10.1038/ncomms10547 Authors: Saidur Rahman Bakaul, Claudy Rayan Serrao, Michelle Lee, Chun Wing Yeung, Asis Sarker, Shang-Lin Hsu, Ajay Kumar Yadav, Liv Dedon, Long You, Asif Islam Khan, James David Clarkson, Chenming Hu, Ramamoorthy Ramesh, Sayeef Salahudd...περισσότερα »
Optogenetic control of nuclear protein export
Article Light-inducible control of protein subcellular localization holds great promise for synthetic biology applications and insights into basic cell biology. Here the authors develop a genetically-encoded light-inducible nuclear export system and apply it to a synthetic repressor and p53 transcriptional activity. Nature Communications doi: 10.1038/ncomms10624 Authors: Dominik Niopek, Pierre Wehler, Julia Roensch, Roland Eils, Barbara Di Ventura [image: 20SpCNU] from #Medicine-Sfakianakis via simeraentaxei on Inoreader http://ift.tt/1Xf6x6h via IFTTT from #Med Blogs by Alex... περισσότερα »
Artifacts Affecting Musculoskeletal Magnetic Resonance Imaging: Their Origins and Solutions
Publication date: Available online 8 February 2016 *Source:*Current Problems in Diagnostic Radiology Author(s): Eira Roth, Michael Hoff, Michael L. Richardson, Alice S. Ha, Jack Porrino Amongst articles within the radiology literature, few present the manifestations of magnetic resonance imaging artifacts (MRI) in a clinically-oriented manner. Recognizing such artifacts is imperative given the increasing clinical use of MRI and the emphasis by the American Board of Radiology on practical physics applications. The purpose of this article is to present magnetic resonance physics princ... περισσότερα »
Three-Dimensional Quantitative Validation of Breast MRI Background Parenchymal Enhancement Assessments
Publication date: Available online 8 February 2016 *Source:*Current Problems in Diagnostic Radiology Author(s): Richard Ha, Eralda Mema, Xiaotao Guo, Victoria Mango, Elise Desperito, Jason Ha, Ralph Wynn, Binsheng Zhao IntroductionThe MRI background parenchymal enhancement (BPE) and its clinical significance as a bio-marker of breast cancer risk has been proposed based on qualitative studies. Previous BPE quantification studies lack appropriate correlation with BPE qualitative assessments. The purpose of this study is to validate our three-dimensional (3D) BPE quantification method ...περισσότερα »
Evaluation of Speech Amplification Devices in Parkinson’s Disease.
Conclusions: This study found preliminary evidence of improved speech performance with device use for individuals with PD. A tentative hierarchy is suggested for device recommendations. Future research is needed to determine which measures will predict long-term device acceptance in PD. PMID: 26847491 [PubMed – as supplied by publisher] (Source: American Journal of Speech-Language Pathology) from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://ift.tt/1ScHIsc via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http:/... περισσότερα »
Mechanical evidence that Australopithecus sediba was limited in its ability to eat hard foods
Article Dietary adaptations of extinct early humans are often inferred from dental microwear data. Here, the authors employ mechanical analyses to show that Australopithecus sediba had limited ability to consume hard foods. Nature Communications doi: 10.1038/ncomms10596 Authors: Justin A. Ledogar, Amanda L. Smith, Stefano Benazzi, Gerhard W. Weber, Mark A. Spencer, Keely B. Carlson, Kieran P. McNulty, Paul C. Dechow, Ian R. Grosse, Callum F. Ross, Brian G. Richmond, Barth W. Wright, Qian Wang, Craig Byron, Kristian J. Carlson, Darryl J. de Ruiter, Lee R. Berger, Kelli Tamvada, Le... περισσότερα »
Description and Evaluation of a Home-Based, Parent-Administered Program for Teaching Enhanced Natural Gestures to Individuals With Angelman Syndrome.
Conclusions: ENGs may, in conjunction with other forms of augmentative and alternative communication, represent a viable method of communication for many individuals with Angelman syndrome. Further research is warranted to explore the feasibility of ENGs with other populations of individuals with severe disabilities and complex communication challenges. PMID: 26847597 [PubMed – as supplied by publisher] (Source: American Journal of Speech-Language Pathology) from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://ift.tt/1UZUSa1 via IFTTT from #Med Blogs by Alexa...περισσότερα »
Shaping metallic glasses by electromagnetic pulsing
[image: ncomms10576-f1.jpg] Article Metallic glasses can be softened to different shapes whilst maintaining mechanical properties, and the related thermoplastic processing requires a heating source and an applied force. Here, the authors show an effective thermoplastic approach by a coupling between electric pulses and a magnetic field. Nature Communications doi: 10.1038/ncomms10576 Authors: Georg Kaltenboeck, Marios D. Demetriou, Scott Roberts, William L. Johnson [image: 1PLnF1S] from #Medicine-Sfakianakis via simeraentaxei on Inoreader http://ift.tt/1KCc6tG via IFTTT from ... περισσότερα »
Sound Production Treatment: Synthesis and Quantification of Outcomes
Conclusion These benchmarks may assist in evaluating the effects of interventions for individuals with AOS utilizing similar outcome measures in both clinical and research settings. (Source: American Journal of Speech-Language Pathology) from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://ift.tt/1nUhsWH via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1KCctUR via IFTTT
Relationships Between Formant Frequencies of Sustained Vowels and Tongue Contours Measured by Ultrasonography
Conclusions Ultrasonographic measurements of tongue contour correlated well to the formant frequencies. The results stressed the importance of tongue shaping in articulation. Although more studies are necessary in clinical implications, disorders associated with abnormal tongue shaping may be the target applications in the future. (Source: American Journal of Speech-Language Pathology) from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://ift.tt/1Q633n5 via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.t... περισσότερα »
Using Spoken Language Benchmarks to Characterize the Expressive Language Skills of Young Children With Autism Spectrum Disorders
Conclusion The spoken language benchmarks are useful for characterizing early communication profiles and investigating features that influence expressive language growth. (Source: American Journal of Speech-Language Pathology) from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://ift.tt/1nUdOfj via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1KCcqsd via IFTTT
Editor’s Perspective: Supplements and Forums
Purpose In this article, the Editor of the American Journal of Speech-Language Pathology reflects on the distinction between the Clinical or Research Forum and the Supplement—and the important contributions that each dissemination format makes. (Source: American Journal of Speech-Language Pathology) from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://ift.tt/1Q631eW via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/23U3l4G via IFTTT
The effect of upper limb casting on gait pattern.
Casting of the arm may interfere with normal walking patterns because of additional load of the cast or prevention of arm swing. This study aimed to determine the effect of applying various casts on temporospatial walking parameters, including gait velocity and cadence, step length, and single limb support. A computerized gait system was used to assess these variables for 23 healthy individuals in four walking modes: normal walking, with a cast above the elbow and a sling, and with a cast below the elbow, with and without a sling. Thirteen participants had their dominant hand caste... περισσότερα »
A Leukocyte Immune-Type Receptor Subset Is a Marker of Antiviral Cytotoxic Cells in Channel Catfish, Ictalurus punctatus INFECTIOUS DISEASE AND HOST RESPONSE
Channel catfish, *Ictalurus punctatus*, leukocyte immune type receptors (LITRs) represent a multigene family that encodes Ig superfamily proteins that mediate activating or inhibitory signaling. In this study, we demonstrate the use of mAb CC41 to monitor viral cytotoxic responses in catfish and determine that CC41 binds to a subset of LITRs on the surface of catfish clonal CTLs. Homozygous gynogenetic catfish were immunized with channel catfish virus (CCV)–infected MHC-matched clonal T cells (G14D-CCV), and PBL were collected at various times after immunization for flow cytometri... περισσότερα »
Modulatory effect of romantic love on value estimation and its neural mechanism.
Any decision that is based upon personal preferences utilizes subjective values; however, for objectively equivalent items, whether romantic love modulates subjective value as well as the neural mechanism of this process remains unknown. In this functional MRI study, 30 items with equivalent value were first selected and assigned into three groups, and participants were trained to associate each group of items with their lover, a familiar person, or an unfamiliar person. Thereafter, the participant rated the values of the items during functional MRI scanning, after which they perfor... περισσότερα »
Podcasting in the STEM disciplines: the implications of supplementary lecture recording and 'lecture flipping
Lecture capture or 'podcasting' technology offers a new and engaging format of learning materials that can be used to increase the flexibility and interactivity of learning and teaching environments. Here we discuss different ways that these recordings can be incorporated into STEM discipline teaching, and the impact this can have on students' learning. from #Infections via alexandrossfakianakis on Inoreader http://ift.tt/1ScG1v2 via IFTTT
Cry-like genes, in an uncommon gene configuration, produce a crystal that localizes within the exosporium when expressed in an acrystalliferous strain of Bacillus thuringiensis
Cry proteins are pesticidal toxins produced by the bacterium *Bacillus thuringiensis* (Bt), which aggregate in sporulating cells to form a crystal. Except in a relatively few cases, these crystals are located outside the exosporium that surrounds the spore. Bt2-56 is a strain of Bt that has the relatively uncommon characteristic of locating its Cry protein-containing crystal within the exosporium, and in association with a long, multifiber filament. With the ultimate goal of both understanding and manipulating the localization of Cry proteins within the exosporium, we sought to id... περισσότερα »
Prevention of antibiotic-nonsusceptible invasive pneumococcal disease with the 13-valent pneumococcal conjugate vaccine
We present the impact of PCV13 on antibiotic-nonsusceptible IPD for the first time since its US introduction. From 2009-2013, rates of serotypes included in PCV13 but not in PCV7 decreased; rates of non-PCV13 serotypes increased slightly, but no serotype dominated. from #Infections via alexandrossfakianakis on Inoreader http://ift.tt/1QSbQ9a via IFTTT
Repeated Cycles of Recombinant Human Interleukin-7 in HIV-Infected Patients with low CD4 T cell Reconstitution on Antiretroviral Therapy: Results of two Phase II Multicentre Studies
In this pooled analysis of two phase II trials, repeated cycles of recombinant human Interleukin-7 administration were safe and led to a sustained increase of CD4 T cell count in HIV-infected individuals with low CD4 T cell reconstitution on antiretroviral therapy. from #Infections via alexandrossfakianakis on Inoreader http://ift.tt/1KCdnAX via IFTTT
Faropenem Consumption is Increasing in India
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A clinical and epidemiological investigation of the first reported human infection with the zoonotic parasite Trypanosoma evansi in Southeast Asia
Here we show that the bovid associated parasite *Trypanosoma evansi* is endemic in Vietnam and has zoonotic potential. Our study describes the first laboratory confirmed human case of *Trypanosoma evansi*in a previously healthy individual without APOL1 deficiency. from #Infections via alexandrossfakianakis on Inoreader http://ift.tt/1KCdpsA via IFTTT
Whole-genome sequencing reveals the origin and rapid evolution of an emerging outbreak strain of Streptococcus pneumoniae 12F
The Canadian pneumococcal 12F outbreak was caused by a novel strain that acquired macrolide resistance through horizontal gene transfer and developed fluoroquinolone resistance via step-wise mutation. Rapid expansion of this clone in North America warrants heightened surveillance. from #Infections via alexandrossfakianakis on Inoreader http://ift.tt/1QSbNdw via IFTTT
Treatment of Asymptomatic Bacteriuria
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15 April News
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Protective Effect of Contemporary Pertussis Vaccines: A Systematic Review and Meta-analysis
In this meta-analysis of pertussis vaccine efficacy/effectiveness studies focusing on formulations currently on the market, the overall short-term (<3 years after completion of the primary series) protective effect against WHO-defined pertussis was lower for acellular vaccines than for whole-cell vaccines. from #Infections via alexandrossfakianakis on Inoreader http://ift.tt/23U12OV via IFTTT
The History of Articulators: The Contributions of Rudolph L. Hanau and His Company—Part II
Abstract This article is an historical overview of the Hanau Engineering Company from the time of Rudolph Hanau's death in 1930 to the present. It explores the development of many articulators intended both for removable and fixed prosthodontic restorations. The article is divided into the eras of the company's corporate history, and it reviews articulator designs and major improvements made during each of those periods. from #Dental via xlomafota13 on Inoreader http://ift.tt/20G9WRd via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel ... περισσότερα »
Surgical Optimization of Motor Recovery in Face Transplantation.
Background: Face transplantation (FT) has emerged as a viable option for treating devastating facial injuries. Most reported outcomes have demonstrated satisfactory motor and sensory restoration despite differences in technique. The authors have developed an algorithm of facial nerve management in these challenging patients. Our principles of management are illustrated by 2 specific patients. Methods: A retrospective analysis of prospectively collected data on 2 full face transplants was performed. Both patients required nerve grafting during full FT. Patient 1 due to short donor fa... περισσότερα »
An In Vitro Comparison of the Marginal Adaptation Accuracy of CAD/CAM Restorations Using Different Impression Systems
Abstract Purpose To compare the marginal adaptation of 3-unit zirconia fixed dental prostheses (FDPs) obtained from intraoral digital scanners (Lava True Definition, Cadent iTero), scanning of a conventional silicone impression, and the resulting master cast with an extraoral scanner (3Shape lab scanner). Materials and Methods One reference model was fabricated from intact, non-carious, unrestored human mandibular left first premolar and first molar teeth (teeth #19 and 21), prepared for a three-unit all-ceramic FDP. Impressions of the reference model were obtained using four im... περισσότερα »
Toxicities and early outcomes in a phase 1 trial of photodynamic therapy for premalignant and early stage head and neck tumors
Photodynamic therapy (PDT) uses a photosensitizing agent and light to kill cells, involving delivery of a photosensitizer or photosensitizer precursor followed by illumination at a specific wavelength of light. The appeal of PDT in oncology has been that photosensitizers such as Photofrin are retained in tumor tissues for longer periods compared to normal tissue. The selectivity of photosensitizer for diseased tissue, as well as the ability to target the light directly to diseased areas, has prompted interest in studying PDT as an organ-preserving treatment for premalignant and ma... περισσότερα »
Influence of Liquid Lubrication on the Screw-Joint Stability of Y-TZP Implant Abutment Systems
Abstract Purpose To evaluate the effectiveness of abutment screws coated with liquid Vaseline on the screw-joint stability of yttria-stabilized tetragonal zirconia (Y-TZP) abutment systems. Materials and Methods Forty Y-TZP prefabricated abutments, 20 Neodent and 20 Bionnovation, were tightened to 20 Ncm on their respective external hexagon implants, and divided into four groups (n = 10) according to the screws: coated with Vaseline or uncoated. The removal torque (RT) value of the abutment screw was measured before and after loading. A cyclic loading (0.5 × 106 cycles; 15 Hz) b... περισσότερα »
The phenotype of migraine with unilateral cranial autonomic symptoms documents increased peripheral and central trigeminal sensitization. A case series of 757 patients
otolaryngologistsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.Alexandros,,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,tel : 00302841026182,00306932607174Πριν από 1 ώρα
Background Migraine with unilateral cranial autonomic symptoms (UAS) is a putative migraine endophenotype with convincing response to trigeminal-targeted treatments that still needs a thorough characterization. Objective The objective of this article is to carefully investigate the clinical phenotype of migraine with UAS in a large group of patients for more accurate migraine diagnoses, improved clinical […]
Early-life respiratory infections and asthma development: role in disease pathogenesis and potential targets for disease prevention.
otolaryngologistsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.Alexandros,,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,tel : 00302841026182,00306932607174Πριν από 1 ώρα
Purpose of review: This article presents recent findings and perspectives on the relationship between early-life respiratory infections and asthma inception, and discusses emerging concepts on strategies that target these infectious agents for asthma prevention. Recent findings: Cumulative evidence supports the role of early-life viral infections, especially respiratory syncytial virus and human rhinovirus, as major antecedents […]
Response to the Letter Entitled “Archegonous Cystic Odontoma Is Not Necessarily Primordial” by Ide et al.
otolaryngologistsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.Alexandros,,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,tel : 00302841026182,00306932607174Πριν από 1 ώρα
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Issue Information – TOC
otolaryngologistsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.Alexandros,,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,tel : 00302841026182,00306932607174Πριν από 1 ώρα
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Planning digital artery perforators using color Doppler ultrasonography: a preliminary report
otolaryngologistsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.Alexandros,,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,tel : 00302841026182,00306932607174Πριν από 1 ώρα
Publication date: Available online 8 February 2016 Source:Journal of Plastic, Reconstructive & Aesthetic Surgery Author(s): Kosuke Shintani, Kiyohito Takamatsu, Takuya Uemura, Ema Onode, Mitsuhiro Okada, Kenichi Kazuki, Hiroaki Nakamura Digital artery perforator (DAP) flaps have been applied for the coverage of finger soft tissue defects. While an advantage of this method is that there is […]
Toxicities and early outcomes in a phase 1 trial of photodynamic therapy for premalignant and early stage head and neck tumors
otolaryngologistsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.Alexandros,,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,tel : 00302841026182,00306932607174Πριν από 1 ώρα
Publication date: Available online 8 February 2016 Source:Oral Oncology Author(s): Peter H. Ahn, Harry Quon, Bert W. O’Malley, Gregory Weinstein, Ara Chalian, Kelly Malloy, Joshua H. Atkins, Thomas Sollecito, Martin Greenberg, Sally McNulty, Alexander Lin, Timothy C. Zhu, Jarod C. Finlay, Keith Cengel, Virginia Livolsi, Michael Feldman, Rosemarie Mick, Theresa M. Busch ObjectivesManagement of early […]
GABA transmission via ATP-dependent K+ channels regulates {alpha}-synuclein secretion in mouse striatum
otolaryngologistsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.Alexandros,,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,tel : 00302841026182,00306932607174Πριν από 1 ώρα
α-Synuclein is readily released in human and mouse brain parenchyma, even though the normal function of the secreted protein has not been yet elucidated. Under pathological conditions, such as in Parkinson’s disease, pathologically relevant species of α-synuclein have been shown to propagate between neurons in a prion-like manner, although the mechanism by which α-synuclein transfer […]
The topograpy of demyelination and neurodegeneration in the multiple sclerosis brain
otolaryngologistsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.Alexandros,,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,tel : 00302841026182,00306932607174Πριν από 1 ώρα
Multiple sclerosis is a chronic inflammatory disease with primary demyelination and neurodegeneration in the central nervous system. In our study we analysed demyelination and neurodegeneration in a large series of multiple sclerosis brains and provide a map that displays the frequency of different brain areas to be affected by these processes. Demyelination in the cerebral […]
Mapping neuroplastic potential in brain-damaged patients
otolaryngologistsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.Alexandros,,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,tel : 00302841026182,00306932607174Πριν από 1 ώρα
It is increasingly acknowledged that the brain is highly plastic. However, the anatomic factors governing the potential for neuroplasticity have hardly been investigated. To bridge this knowledge gap, we generated a probabilistic atlas of functional plasticity derived from both anatomic magnetic resonance imaging results and intraoperative mapping data on 231 patients having undergone surgery for […]
Thalamic pain: anatomical and physiological indices of prediction
otolaryngologistsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.Alexandros,,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,tel : 00302841026182,00306932607174Πριν από 1 ώρα
Thalamic pain is a severe and treatment-resistant type of central pain that may develop after thalamic stroke. Lesions within the ventrocaudal regions of the thalamus carry the highest risk to develop pain, but its emergence in individual patients remains impossible to predict. Because damage to the spino-thalamo-cortical system is a crucial factor in the development […]
Systematic review with meta-analysis: faecal occult blood tests show lower colorectal cancer detection rates in the proximal colon in colonoscopy-verified diagnostic studies
Summary Background The performance of faecal occult blood tests (FOBTs) to screen proximally located colorectal cancer (CRC) has produced inconsistent results. Aim To assess in a meta-analysis, the diagnostic accuracy of FOBTs for relative detection of CRC according to anatomical location of CRC. Methods Diagnostic studies including both symptomatic and asymptomatic cohorts assessing performance of FOBTs for CRC were searched from MEDINE and EMBASE. Primary outcome was accuracy of FOBTs according to the anatomical location of CRC. Bivariate random-effects model was used. Subgrou... περισσότερα »
The features of mucosa-associated microbiota in primary sclerosing cholangitis
Summary Background Little is known about the role of the microbiome in primary sclerosing cholangitis. Aim To explore the mucosa-associated microbiota in primary sclerosing cholangitis (PSC) patients across different locations in the gut, and to compare it with inflammatory bowel disease (IBD)-only patients and healthy controls. Methods Biopsies from the terminal ileum, right colon, and left colon were collected from patients and healthy controls undergoing colonoscopy. Microbiota profiling using bacterial 16S rRNA sequencing was performed on all biopsies. Results Forty-four... περισσότερα »
Planning digital artery perforators using color Doppler ultrasonography: a preliminary report
Publication date: Available online 8 February 2016 *Source:*Journal of Plastic, Reconstructive & Aesthetic Surgery Author(s): Kosuke Shintani, Kiyohito Takamatsu, Takuya Uemura, Ema Onode, Mitsuhiro Okada, Kenichi Kazuki, Hiroaki Nakamura Digital artery perforator (DAP) flaps have been applied for the coverage of finger soft tissue defects. While an advantage of this method is that there is no scarification of the digital arteries, it is difficult to identify the location of the perforators during intraoperative elevation of the DAP flap. In this study, anatomically reliable location... περισσότερα »
Highly Accurate Sequencing of Full-Length Immune Repertoire Amplicons Using Tn5-Enabled and Molecular Identifier-Guided Amplicon Assembly NOVEL IMMUNOLOGICAL METHODS
Ab repertoire sequencing is a powerful tool to analyze the adaptive immune system. To sequence entire Ab repertoires, amplicons are created from Ab H chain (IgH) transcripts and sequenced on a high-throughput sequencer. The field of immune repertoire sequencing is growing rapidly and the protocols used are steadily improving; however, thus far, immune repertoire sequencing protocols have not been able to sequence full-length immune repertoires including the entire IgH V region and enough of the IgH C region to identify isotype subtypes. In this study, we present a method that comb...περισσότερα »
Regulation of Adenosine Deaminase on Induced Mouse Experimental Autoimmune Uveitis IMMUNOTHERAPY AND VACCINES
Adenosine is an important regulator of the immune response, and adenosine deaminase (ADA) inhibits this regulatory effect by converting adenosine into functionally inactive molecules. Studies showed that adenosine receptor agonists can be anti- or proinflammatory. Clarification of the mechanisms that cause these opposing effects should provide a better guide for therapeutic intervention. In this study, we investigated the effect of ADA on the development of experimental autoimmune uveitis (EAU) induced by immunizing EAU-prone mice with a known uveitogenic peptide, IRBP1–20. Our re... περισσότερα »
IL-1 Receptor Signaling on Graft Parenchymal Cells Regulates Memory and De Novo Donor-Reactive CD8 T Cell Responses to Cardiac Allografts TRANSPLANTATION
Reperfusion of organ allografts induces a potent inflammatory response that directs rapid memory T cell, neutrophil, and macrophage graft infiltration and their activation to express functions mediating graft tissue injury. The role of cardiac allograft IL-1 receptor (IL-1R) signaling in this early inflammation and the downstream primary alloimmune response was investigated. When compared with complete MHC-mismatched wild-type cardiac allografts, IL-1R–/– allografts had marked decreases in endogenous memory CD8 T cell and neutrophil infiltration and expression of proinflammatory m... περισσότερα »
Editor’s Perspective: Supplements and Forums
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 1 ώρα
Purpose In this article, the Editor of the American Journal of Speech-Language Pathology reflects on the distinction between the Clinical or Research Forum and the Supplement—and the important contributions that each dissemination format makes. (Source: American Journal of Speech-Language Pathology) from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://ift.tt/1Q631eW via IFTTT from #Med […]
The effect of upper limb casting on gait pattern.
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 1 ώρα
Casting of the arm may interfere with normal walking patterns because of additional load of the cast or prevention of arm swing. This study aimed to determine the effect of applying various casts on temporospatial walking parameters, including gait velocity and cadence, step length, and single limb support. A computerized gait system was used to […]
A Leukocyte Immune-Type Receptor Subset Is a Marker of Antiviral Cytotoxic Cells in Channel Catfish, Ictalurus punctatus INFECTIOUS DISEASE AND HOST RESPONSE
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 1 ώρα
Channel catfish, Ictalurus punctatus, leukocyte immune type receptors (LITRs) represent a multigene family that encodes Ig superfamily proteins that mediate activating or inhibitory signaling. In this study, we demonstrate the use of mAb CC41 to monitor viral cytotoxic responses in catfish and determine that CC41 binds to a subset of LITRs on the surface of […]
Highly Accurate Sequencing of Full-Length Immune Repertoire Amplicons Using Tn5-Enabled and Molecular Identifier-Guided Amplicon Assembly NOVEL IMMUNOLOGICAL METHODS
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 1 ώρα
Ab repertoire sequencing is a powerful tool to analyze the adaptive immune system. To sequence entire Ab repertoires, amplicons are created from Ab H chain (IgH) transcripts and sequenced on a high-throughput sequencer. The field of immune repertoire sequencing is growing rapidly and the protocols used are steadily improving; however, thus far, immune repertoire sequencing […]
Regulation of Adenosine Deaminase on Induced Mouse Experimental Autoimmune Uveitis IMMUNOTHERAPY AND VACCINES
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 1 ώρα
Adenosine is an important regulator of the immune response, and adenosine deaminase (ADA) inhibits this regulatory effect by converting adenosine into functionally inactive molecules. Studies showed that adenosine receptor agonists can be anti- or proinflammatory. Clarification of the mechanisms that cause these opposing effects should provide a better guide for therapeutic intervention. In this study, […]
IL-1 Receptor Signaling on Graft Parenchymal Cells Regulates Memory and De Novo Donor-Reactive CD8 T Cell Responses to Cardiac Allografts TRANSPLANTATION
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 1 ώρα
Reperfusion of organ allografts induces a potent inflammatory response that directs rapid memory T cell, neutrophil, and macrophage graft infiltration and their activation to express functions mediating graft tissue injury. The role of cardiac allograft IL-1 receptor (IL-1R) signaling in this early inflammation and the downstream primary alloimmune response was investigated. When compared with complete […]
Sassuolo-Palermo, quattro gol e spettacolo – La Citta di Salerno
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 1 ώρα
La Citta di Salerno Sassuolo-Palermo, quattro gol e spettacolo La Citta di Salerno Importante, al contrario, il punto conquistato (in chiave salvezza) dal Palermo, che ha confermato i recenti progressi, mostrando la compattezza mancata mercoledì sera contro il Milan e un Sorrentino in grande spolvero. Al 12′ bella conclusione di … Il Sassuolo non riesce […]
Novel redox sensitive system based on SWCNTs
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 1 ώρα
Hou L, Yang X, Ren J, Wang Y, Zhang H, Feng Q, Shi Y, Shan X, Yuan Y, Zhang Z from #ORL-AlexandrosSfakianakis via simeraentaxei on Inoreader http://ift.tt/1PylI5A via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
Genomic Testing for Gemcitabine-Based Treatment of Pancreatic Cancer
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 1 ώρα
from #ORL-AlexandrosSfakianakis via simeraentaxei on Inoreader http://ift.tt/1PLh5Zd via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
Relevance of Sp Binding Site Polymorphism in WWOX for Treatment Outcome in Pancreatic Cancer
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 1 ώρα
Background: A genome-wide association study (GWAS) suggested inherited genetic single-nucleotide polymorphisms (SNPs) affecting overall survival (OS) in advanced pancreatic cancer. To identify robust clinical biomarkers, we tested the strongest reported candidate loci in an independent patient cohort, assessed cellular drug sensitivity, and evaluated molecular effects. Methods: This study comprised 381 patients with histologically verified pancreatic […]
Association of Interferon Regulatory Factor-4 Polymorphism rs12203592 With Divergent Melanoma Pathways
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 1 ώρα
Background: Solar elastosis and neval remnants are histologic markers characteristic of divergent melanoma pathways linked to differences in age at onset, host phenotype, and sun exposure. However, the association between these pathway markers and newly identified low-penetrance melanoma susceptibility loci remains unknown. Methods: In the Genes, Environment and Melanoma (GEM) Study, 2103 Caucasian participants had […]
Potential Role for YB-1 in Castration-Resistant Prostate Cancer and Resistance to Enzalutamide Through the Androgen Receptor V7
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 1 ώρα
Background: Although androgen deprivation therapy for advanced prostate cancer initially exerts excellent anticancer effects, most prostate cancer treated with androgen deprivation therapy eventually recurs as castration-resistant prostate cancer (CRPC). Although aberrant kinase activation has been proposed as a mechanism of castration resistance, comprehensive kinase profiles in CRPC remain unknown. Therefore, we aimed to elucidate the […]
Modification of Occupational Exposures on Bladder Cancer Risk by Common Genetic Polymorphisms
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 1 ώρα
from #ORL-AlexandrosSfakianakis via simeraentaxei on Inoreader http://ift.tt/1PLh73l via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
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alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 1 ώρα
from #ORL-AlexandrosSfakianakis via simeraentaxei on Inoreader http://ift.tt/20Siukm via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
Regorafenib Also Can Cause Osteonecrosis of the Jaw
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 1 ώρα
from #ORL-AlexandrosSfakianakis via simeraentaxei on Inoreader http://ift.tt/1PLh5IX via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
Chelsea Councilman Proposes Ban on Smokeless Tobacco at Sports Stadiums – DNAinfo
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 1 ώρα
DNAinfo Chelsea Councilman Proposes Ban on Smokeless Tobacco at Sports Stadiums DNAinfo Baseball greats Tony Gwynn, who succumbed to salivary gland cancer in 2014, and Curt Schilling, who was treated for oral cancer a few years ago, both attributed their medical conditions to prolonged chewing tobacco use, the statement said. In 2013, the … from […]
Common electronic origin of superconductivity in (Li,Fe)OHFeSe bulk superconductor and single-layer FeSe/SrTiO3 films
Article The mechanism of high-temperature superconductivity in the iron-based materials remains not fully understood. Here, the authors report on ARPES measurements on an FeSe-based bulk superconductor, whose electronic properties are found to be similar to those of single-layer FeSe/STO films. Nature Communications doi: 10.1038/ncomms10608 Authors: Lin Zhao, Aiji Liang, Dongna Yuan, Yong Hu, Defa Liu,… Continue reading Common electronic origin of superconductivity in (Li,Fe)OHFeSe bulk superconductor and single-layer FeSe/SrTiO3 films
EXPOSURE TO POLYBROMINATED DIPHENYL ETHERS ASSOCIATES WITH HYPOTHYROIDISM
EXPOSURE TO POLYBROMINATED DIPHENYL ETHERS ASSOCIATES WITH HYPOTHYROIDISM Oulhote Y1, Chevrier J1, Bouchard MF Exposure to Polybrominated Diphenyl Ethers (PBDEs) and Hypothyroidism in Canadian Women. J Clin Endocrinol Metab. 2016 Feb;101(2):590-8. doi: 10.1210/jc.2015-2659. Epub 2015 Nov 25. Polybrominated diphenyl ethers (PBDEs) are used as flame retardants in a wide range of products, resulting in widespread… Continue reading EXPOSURE TO POLYBROMINATED DIPHENYL ETHERS ASSOCIATES WITH HYPOTHYROIDISM
Lysophosphatidic acid activates Arf6 to promote the mesenchymal malignancy of renal cancer
Article Acquisition of mesenchymal properties by cancer cells is a critical event for the development of malignancy. Here, the authors show that in renal cancer cells, lysosphosphatidic acid does not utilize the RhoA pathway but specifically activates the Arf6 mesenchymal pathway via its GPCRs and EFA6 to promote invasion, metastasis and drug resistance. Nature Communications… Continue reading Lysophosphatidic acid activates Arf6 to promote the mesenchymal malignancy of renal cancer
Three-Dimensional Quantitative Validation of Breast MRI Background Parenchymal Enhancement Assessments
Publication date: Available online 8 February 2016 Source:Current Problems in Diagnostic Radiology Author(s): Richard Ha, Eralda Mema, Xiaotao Guo, Victoria Mango, Elise Desperito, Jason Ha, Ralph Wynn, Binsheng Zhao IntroductionThe MRI background parenchymal enhancement (BPE) and its clinical significance as a bio-marker of breast cancer risk has been proposed based on qualitative studies. Previous BPE… Continue reading Three-Dimensional Quantitative Validation of Breast MRI Background Parenchymal Enhancement Assessments
Single crystal functional oxides on silicon
Article Synthesis of single-crystal complex-oxide films directly on silicon is difficult due to differing interfacial chemistry. Here, the authors demonstrate room-temperature integration of single-crystal lead zirconate titanate on to silicon to act as a gate insulator in a field-effect transistor. Nature Communications doi: 10.1038/ncomms10547 Authors: Saidur Rahman Bakaul, Claudy Rayan Serrao, Michelle Lee, Chun Wing… Continue reading Single crystal functional oxides on silicon
Artifacts Affecting Musculoskeletal Magnetic Resonance Imaging: Their Origins and Solutions
Publication date: Available online 8 February 2016 Source:Current Problems in Diagnostic Radiology Author(s): Eira Roth, Michael Hoff, Michael L. Richardson, Alice S. Ha, Jack Porrino Amongst articles within the radiology literature, few present the manifestations of magnetic resonance imaging artifacts (MRI) in a clinically-oriented manner. Recognizing such artifacts is imperative given the increasing clinical use… Continue reading Artifacts Affecting Musculoskeletal Magnetic Resonance Imaging: Their Origins and Solutions
Optogenetic control of nuclear protein export
Article Light-inducible control of protein subcellular localization holds great promise for synthetic biology applications and insights into basic cell biology. Here the authors develop a genetically-encoded light-inducible nuclear export system and apply it to a synthetic repressor and p53 transcriptional activity. Nature Communications doi: 10.1038/ncomms10624 Authors: Dominik Niopek, Pierre Wehler, Julia Roensch, Roland Eils, Barbara… Continue reading Optogenetic control of nuclear protein export
Description and Evaluation of a Home-Based, Parent-Administered Program for Teaching Enhanced Natural Gestures to Individuals With Angelman Syndrome.
Conclusions: ENGs may, in conjunction with other forms of augmentative and alternative communication, represent a viable method of communication for many individuals with Angelman syndrome. Further research is warranted to explore the feasibility of ENGs with other populations of individuals with severe disabilities and complex communication challenges. PMID: 26847597 [PubMed – as supplied by publisher]… Continue reading Description and Evaluation of a Home-Based, Parent-Administered Program for Teaching Enhanced Natural Gestures to Individuals With Angelman Syndrome.
Shaping metallic glasses by electromagnetic pulsing
Article Metallic glasses can be softened to different shapes whilst maintaining mechanical properties, and the related thermoplastic processing requires a heating source and an applied force. Here, the authors show an effective thermoplastic approach by a coupling between electric pulses and a magnetic field. Nature Communications doi: 10.1038/ncomms10576 Authors: Georg Kaltenboeck, Marios D. Demetriou, Scott… Continue reading Shaping metallic glasses by electromagnetic pulsing
Evaluation of Speech Amplification Devices in Parkinson’s Disease.
Conclusions: This study found preliminary evidence of improved speech performance with device use for individuals with PD. A tentative hierarchy is suggested for device recommendations. Future research is needed to determine which measures will predict long-term device acceptance in PD. PMID: 26847491 [PubMed – as supplied by publisher] (Source: American Journal of Speech-Language Pathology) from… Continue reading Evaluation of Speech Amplification Devices in Parkinson’s Disease.
Final Results of the Sunbelt Melanoma Trial: A Multi-Institutional Prospective Randomized Phase III Study Evaluating the Role of Adjuvant High-Dose Interferon Alfa-2b and Completion Lymph Node Dissection for Patients Staged by Sentinel Lymph Node Biopsy Melanoma
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 2 ώρες
Purpose The Sunbelt Melanoma Trial is a prospective randomized trial evaluating the role of high-dose interferon alfa-2b therapy (HDI) or completion lymph node dissection (CLND) for patients with melanoma staged by sentinel lymph node (SLN) biopsy. Patients and Methods Patients were eligible if they were age 18 to 70 years with primary cutaneous melanoma ≥ […]
Sexual Polyploidization in Medicago sativa L.: Impact on the Phenotype, Gene Transcription and Genome Methylation
Polyploidization as the consequence of 2n gamete formation is a prominent mechanism in plant evolution. Studying its effects on the genome and its expression has both basic and applied interest. We crossed two diploid (2n=2x=16) *M. sativa* plants, a *subsp. Falcate* seed parent and a *coerulea x falcate* pollen parent that form a mixture of n and 2n eggs and pollen, respectively. Such cross produced full-sib diploid and tetraploid (2n=4x=32) hybrids, the latter being the result of bilateral sexual polyploidization (BSP). These unique materials allowed us to investigate the effect... περισσότερα »
Sudden appearance of free fluid during endoscopic ultrasound-guided fine-needle aspiration
Mihai Rimbas, Marian Deaconu, Alexandru Croitoru, Andrei Haidar Endoscopic Ultrasound 2016 5(1):55-57 During endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) of a pancreatic malignancy, a small quantity of free fluid, not seen before, suddenly appeared in the view, and time was spent ruling out ongoing hemorrhage. However, during follow-up, the patient gradually developed peritoneal signs and was… Continue reading Sudden appearance of free fluid during endoscopic ultrasound-guided fine-needle aspiration
Mononucleosis
Mononucleosis: Infection with the Epstein-Barr virus (EBV, human herpesvirus 4, HHV-4) in which there is an increase of white blood cells that have a single nucleus (monocytes). The infection can be spread by saliva. Its incubation period is four to eight weeks. Symptoms include fever, fatigue, sore throat, and swollen lymph glands. Mononucleosis can cause… Continue reading Mononucleosis
Endoscopic ultrasound elastography in the diagnosis of incidental malignant mesothelioma
Alexandra Guzman, Raquel Del Valle, Gladys Bravo, Carlos Robles-Medranda Endoscopic Ultrasound 2016 5(1):63-64 from #ORL-AlexandrosSfakianakis via simeraentaxei on Inoreader http://ift.tt/1PyuMY2 via IFTTT
Comparing clinical outcomes for a twelve-month trial of zotarolimus- and everolimus-eluting stents in patients with coronary artery disease: data from the THCRIC registry
Objectives: New-generation coronary stents including zotarolimus- and everolimus-eluting stents (ZES and EES) have been shown to decrease the risk of restenosis. The purpose of this study was to compare the safety and efficacy of ZES and EES over a 12-month clinical follow up, in routine clinical practice. Methods: This is an observational study in which… Continue reading Comparing clinical outcomes for a twelve-month trial of zotarolimus- and everolimus-eluting stents in patients with coronary artery disease: data from the THCRIC registry
Improving Documentation and Communication Using Operative Note Proformas
Abstract Accurate and detailed documentation of surgical procedures is part of good clinical practice, set out by the General Medical Council (GMC). Knee arthroscopy often involves large data sets which require accurate documentation for future assessment and management. This study assesses the quality of documentation of knee arthroscopy, followed by an evaluation of the implementation… Continue reading Improving Documentation and Communication Using Operative Note Proformas
The structure of the transcriptional repressor Kstr in complex with CoA thioester cholesterol metabolites sheds light on the regulation of cholesterol catabolism in Mycobacterium tuberculosis Microbiology
Cholesterol can be a major carbon source for Mycobacterium tuberculosis during infection, both at an early stage in the macrophage phagosome and later within the necrotic granuloma. KstR is a highly conserved TetR-family transcriptional repressor (TFR) that regulates a large set of genes responsible for cholesterol catabolism. Many genes in this regulon, including kstR, are… Continue reading The structure of the transcriptional repressor Kstr in complex with CoA thioester cholesterol metabolites sheds light on the regulation of cholesterol catabolism in Mycobacterium tuberculosis Mi... περισσότερα »
Improving residents’ handovers through just-in-time training for structured communication
Abstract In a recent quality assurance project we learned that nearly half of the handovers we examined were characterized as unsatisfactory by our residents, who provided examples in which their anxiety had been piqued and patient care had been affected. These reports substantiated a growing body of literature on the relationship between the quality of… Continue reading Improving residents’ handovers through just-in-time training for structured communication
Non-lysosomal degradation of singly phosphorylated oligosaccharides initiated by the action of a cytosolic endo-{beta}-N-acetylglucosaminidase Metabolism
Phosphorylated oligosaccharides (POSs) are produced by the degradation of dolichol-linked oligosaccharides (DLOs) by an unclarified mechanism in mammalian cells. While POSs are exclusively found in the cytosol, their intracellular fates remain unclear. Our findings indicate that POSs are catabolized via a non-lysosomal glycan degradation pathway that involves a cytosolic endo-β-N-acetylglucosaminidase (ENGase). Quantitative and structural analyses… Continue reading Non-lysosomal degradation of singly phosphorylated oligosaccharides initiated by the action of a cytosolic endo-{beta}-... περισσότερα »
Cytokines Regulate {beta}-Cell TXNIP via Distinct Mechanisms and Pathways Molecular Bases of Disease
Thioredoxin-interacting protein (TXNIP) is a key regulator of diabetic β-cell apoptosis and dysfunction and TXNIP inhibition prevents diabetes in mouse models of type 1 and type 2 diabetes. While we have previously shown that TXNIP is strongly induced by glucose, any regulation by the pro-inflammatory cytokines tumor necrosis factor α (TNFα), interleukin-1β (IL-1β), and interferon… Continue reading Cytokines Regulate {beta}-Cell TXNIP via Distinct Mechanisms and Pathways Molecular Bases of Disease
Degradation of the Separase-cleaved Rec8, a Meiotic Cohesin Subunit, by the N-end Rule Pathway Cell Biology
The Ate1 arginyltransferase (R transferase) is a component of the N-end rule pathway, which recognizes proteins containing N-terminal degradation signals called N-degrons, polyubiquitylates these proteins and thereby causes their degradation by the proteasome. Ate1 arginylates N-terminal Asp, Glu or (oxidized) Cys. The resulting N-terminal Arg is recognized by ubiquitin ligases of the N-end rule pathway.… Continue reading Degradation of the Separase-cleaved Rec8, a Meiotic Cohesin Subunit, by the N-end Rule Pathway Cell Biology
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