Krithiga Ramachandran, Reshu Agarwal, Chhagan Bihari, Vikram Bhatia, Ekta GuptaJournal of Family Medicine and Primary Care 2020 9(5):2502-2504 We report a case of 55-year-old female with chief complaints of fever and deranged liver function tests, diagnosed as autoimmune hepatitis (AIH) and under immunosuppressive therapy for two years. Following the failure in clinical improvement, she was started on anti-tubercular therapy (ATT). While investigating the underlying etiology, virological markers...
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Bhavna Sahni, Kiran Bala, Tejinder Kumar, Akash NarangyalJournal of Family Medicine and Primary Care 2020 9(5):2332-2336 Context: “Aging India” has become a phenomenon of public health importance. Old age is beset with physical, mental, and social challenges. Among these, mental health concerns are least prioritized in most of the developing countries with depression being the most common and easy to screen. Aims: To assess the burden of geriatric depression and determine its association with...
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Kartik Singhai, Navratan Suthar, Pratibha GehlawatJournal of Family Medicine and Primary Care 2020 9(5):2509-2510 The three Ds of geriatric psychiatry—delirium, dementia, and depression are common and challenging diagnoses among elderly. Delirium is often difficult to diagnose and is an independent risk factor for morbidity and mortality in older adults. Dementia also affects a significant number of older adults and is associated with delirium, depression, frailty, and failure to thrive. It is...
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Perveen Akhtar, Amir Kazmi, Tarun Sharma, Aradhna SharmaJournal of Family Medicine and Primary Care 2020 9(5):2337-2341 Introduction: Ramadan is the ninth month in the lunar Islamic calendar and lasts for about 29–30 days. It is mandatory for all adult individuals of the Islamic faith to fast during the holy month of Ramadan. During this period, healthy Muslims do not eat or drink (i.e., total abstinence from food and fluids) and refrain from tobacco, daily from pre-dawn until dusk (21) . Very...
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Ashok Sunder, Bijaya Mohanty, Abha SinghJournal of Family Medicine and Primary Care 2020 9(5):2514-2516 Allergic angina and allergic myocardial infarction are ubiquitous diseases covering a wide spectrum of mast cell activation disorders, which are associated with acute coronary syndromes and are referred to as ''Kounis Syndrome''. Here, we report a case admitted with dyspnea and mild chest heaviness secondary to bee sting, later diagnosed as Kounis syndrome.
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Deepti Mathur, Surender Deora, Atul Kaushik, Pankaj Bhardwaj, Kuldeep SinghJournal of Family Medicine and Primary Care 2020 9(5):2342-2349 Background and Objectives: Hypertension is an important disease of public health concern. Awareness and medication adherence with diet modification have an important effect on the control of blood pressure and its associated morbidity and mortality. Therefore, this study was conducted to assess the awareness of hypertension, medication adherence, and dietary...
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Mohammad Firoz Nizami, Chandra B Sharma, Bhoopendra Singh, Rishi T GuriaJournal of Family Medicine and Primary Care 2020 9(5):2521-2523 Organophosphorus compounds are absorbed by any route including intramuscular injection. Pyrethroid compounds are less toxic for human but in combination with organophosphates, its toxic effect potentiates due to inhibition of its metabolism. In this case report, a 40-year-old female patient presented with acute onset of pain abdomen, recurrent vomiting, and excessive...
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Soumya K Mandal, Arun Mitra, Yash Alok, Shubhanshu Gupta, Anindo MajumdarJournal of Family Medicine and Primary Care 2020 9(5):2350-2358 Introduction: Although increased taxation on sugar-sweetened beverages (SSBs) and warning labels on their packaging have been successful in other countries, India has not implemented these. It is imperative to understand the user perspectives before implementation, regarding which almost no information exists. Objectives: To assess the awareness and perceptions...
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Adaeze Chidinma Oreh, Etin-osa U Imagbenikaro, Aderemi M Adelaja, Lawrence EzeoguJournal of Family Medicine and Primary Care 2020 9(5):2528-2530 A 39-year-old woman, gravida 4, para 2 + 1 (2 alive) for elective second repeat caesarean delivery on account of two previous caesarean sections and one open myomectomy. Following the caesarean section, she developed sudden cardiac failure and was transferred to the intensive care unit for mechanical ventilation support. Congestive cardiac failure secondary...
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Himel Mondal, Tanmoy Chattopadhyay, Shaikat Mondal, Debasish Das, Sairavi Kiran BiriJournal of Family Medicine and Primary Care 2020 9(5):2359-2363 Background: Reusable suction-cup electrodes are used for recording a 12-lead electrocardiogram (ECG) in resource-limited settings. These electrodes may easily detach if those are attached on a hirsute chest. Additionally, the suction pressure may cause erythema and pain. Aim: The aim of this study was to develop a low-cost strap for holding the suction-cup-based...
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Mudit Kotwal, Esha Vaish, KK Gupta, Ahmad OzairJournal of Family Medicine and Primary Care 2020 9(5):2535-2537 Scrub typhus (ST), hitherto absent from many parts of India, is now recently being recognized as a significant cause of morbidity and mortality throughout the country. Its diverse clinical presentations, low of the index of suspicion by the treating physician, and lack of diagnostic testing in many parts of the country result in delayed treatment, leading to a host of complications....
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Jayanta K Laik, Ravi Kaushal, Ritesh Kumar, Somit Sarkar, Manish GargJournal of Family Medicine and Primary Care 2020 9(5):2364-2369 Context: Osteoarthritis knee is a common degenerative disorder for which various treatment modalities are available. Our aim was to evaluate the functional outcome and effectiveness of proximal fibular osteotomy (PFO) in patients who are unwilling to undergo total knee arthroplasty or high tibial osteotomy (HTO). Aims: To evaluate functional outcome of medial compartment...
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Shankar Roy, Mahendra Meena, Nisha B Dhoot, Ravi KantJournal of Family Medicine and Primary Care 2020 9(5):2541-2543 Chronic obstructive pulmonary disease (COPD) is a common respiratory condition characterized by limitation in airflow. Most of the exacerbations are due to respiratory infections, some are due to environmental pollution. Hypocalcaemia( of any etiology ) is one of the rare causes of acute exacerbation. Here we are reporting a case of severe hypocalcaemia induced bronchospasm, presenting...
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Prashant Gupta, Shantala R Naik, L Ashok, Tanya Khaitan, Anjani Kumar ShuklaJournal of Family Medicine and Primary Care 2020 9(5):2370-2374 Objectives: Pericoronitis of mandibular third molars is commonly encountered in our day to day practice. Most of the case extraction becomes mandatory. This study was carried out to find the incidence of periodontitis on the distal aspect of the second molar adjacent to impacted third molar. Materials and Methods: A total of 400 patients were included in...
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Suman K Panda, Bhagyalakshmi Satyanarayan, Satish K Prasad, Binu KoshyJournal of Family Medicine and Primary Care 2020 9(5):2548-2551 Esophageal cancer is the eighth most common cancer and the sixth most common cause of cancer death globally. Esophageal squamous cell carcinoma (ESCC) accounts for 70%–90% of esophageal cancers worldwide, 5% are adenocarcinoma, and 5% represent rare malignancies and metastases from other organs. We present a case where a 54-year-old lady, with multiple readmissions...
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Diagnosis and risk stratification of coronary artery disease in Yemeni patients using treadmill test
Nouradden N Aljaber, Shanei A Shanei, Sultan Abdulwadoud Alshoabi, Kamal D Alsultan, Moawia B Gameraddin, Khaled M Al-SayaghiJournal of Family Medicine and Primary Care 2020 9(5):2375-2378 Background: Coronary artery disease (CAD) is a common medical problem that remains a great cause of morbidity and mortality. Based on clinical manifestation, CAD span from chronic stable angina to acute coronary syndrome (ACS), which encompasses (1) unstable angina (UA), (2) non-ST-elevation myocardial infarction...
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Nagasubramanyam Vempalli, Sireesha Reddy Konda, Nidhi Kaeley, Bharat B Bhardwaj, Subodh KumarJournal of Family Medicine and Primary Care 2020 9(5):2555-2557 Diaphragmatic hernia (DH) is a common condition following blunt trauma to upper abdomen and is also a commonly missed diagnosis. Its early anticipation in post-traumatic setting is very important to avoid any further life-threatening sequelae. X-ray chest with a nasogastric tube is a simpler way to diagnose this condition. CT scan is a gold...
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Rahul , Narsingh Verma, Mayank Agarwal, Pravesh Vishwakarma, Arvind Kanchan, Pravesh KumarJournal of Family Medicine and Primary Care 2020 9(5):2379-2383 Background: Parental history of cardiovascular disease (CVD) and obesity is associated with delayed parasympathetic nervous system reactivation after exercise. Heart rate recovery (HRRe) after a minute of exercise is inversely related to cardiovascular events. Aim: To determine the effect of body mass index (BMI) and parental CVD history on...
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Y K L. Pradeep, Vijay K Bhogaraju, Monika Pathania, Vyas K Rathaur, Ravi KantJournal of Family Medicine and Primary Care 2020 9(5):2562-2565 Scorpion envenomation is a major public health problem in tropical and sub-tropical countries, especially in Africa, Middle East, Latin America, and India. Even though most of the scorpion envenomation are harmless, it is generally seen with a set of clinical features, such as pain, edema, numbness, and tenderness in the area of the sting but rarely have serious...
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Vijay Parashar, Nitin Jhunjhunwala, Aiyana Parthi, Vaibhav K Singh, Kishan Agarwal, Tejas M KulkarniJournal of Family Medicine and Primary Care 2020 9(5):2384-2387 Background: Undergraduate students can provide valuable opinions and suggestions for modifying the educational program for the enhancement of learning. Therefore, the aim of this study was to explore the preparedness of undergraduate dental students with regard to practice endodontics in the rural and remote areas of India. Materials...
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Darilin Shangpliang, Biswajit Dey, Jonali Das, Pakesh Baishya, Vandana Raphael, Yookarin KhonglahJournal of Family Medicine and Primary Care 2020 9(5):2569-2572 Children with Down syndrome (DS) are found to have an increased risk of developing various hematological disorders. Particularly, they have an increased predisposition to acute leukemia, predominantly the myeloid type known as myeloid leukemia of Down syndrome (ML-DS). The major morphological subtype is acute megakaryoblastic leukemia....
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Jyoti Batra, Ajit Thakur, Shrawan Kumar Meena, Lakbir Singh, Jainendra Kumar, Deepak JuyalJournal of Family Medicine and Primary Care 2020 9(5):2388-2393 Introduction: Lead (Pb) is one of the major occupational pollutants present in the developed and developing countries including India. In humans, Pb can cause a wide range of biological effects depending upon the level and duration of exposure. The goal of this study was to evaluate the blood lead levels (BLLs) and its associated effects on...
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S Sandeep, G Jeevan Kumar, Suraj Potdar, Rishabh Bhanot, Amit S Vathare, Rahul V C Tiwari, B HarshithaJournal of Family Medicine and Primary Care 2020 9(5):2577-2579 Fusion and germination are the anomalies that occur due to some developmental eccentricity during the time of morpho-differentiation of the tooth bud and have a close resemblance to each other. The gemination is an attempt of the division of a single tooth into two and, hence, appears as an enlarged single tooth while the tooth count...
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Ahmed Mohamed Kabel, Shumukh Abdullah Algethami, Bayan Saaed Algethami, Abeer Saleh Alzahrani, Samiah Khalif Almutairi, Ashwaq Shaman AlmutairiJournal of Family Medicine and Primary Care 2020 9(5):2394-2399 Background: Epilepsy is one of the most common disorders that may be associated with negative attitudes among general populations. This may be due to poor public awareness and knowledge toward epilepsy. Aim: To assess knowledge, perceptions and attitudes of students of health-related science...
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Pugazhenthan Thangaraju, Sajitha VenkatesanJournal of Family Medicine and Primary Care 2020 9(5):2583-2584
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Pallawee Choudhary, Irfanul Huda, Anuradha Pandey, Naveen Kumar, Aaysha Tabinda Nabi, Rachna RajJournal of Family Medicine and Primary Care 2020 9(5):2400-2404 Background: Clinical opportunistic screening can be valuable for diagnosis of oral cancer/precancer prior to development of symptoms. Thus, the aim of the present study is to assess the knowledge, perceptions, and present practices of primary health care providers regarding oral cancer screening. Material and Methods: This cross-sectional...
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Pinki Tak, Jitendra Rohilla, Shazia HasanJournal of Family Medicine and Primary Care 2020 9(5):2587-2588
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Nitin Kumar Joshi, Pankaj Bhardwaj, Praveen Suthar, Yogesh Kumar Jain, Vibha Joshi, Balwant MandaJournal of Family Medicine and Primary Care 2020 9(5):2405-2410 Context: e-Health programs are implemented assuming that e-health/digital health can prove beneficial but pieces of evidence for assessing the actual benefits of e-health programs are lacking. Aims: To utilize the benefit evaluation (BE) framework to assess Asha Soft, which is an online payment and performance monitoring system initiative...
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Journal of Family Medicine and Primary Care 2020 9(5):2591-2592
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Human strongyloidiasis a soil-transmitted infection caused by Strongyloides stercoralis is one of the most neglected amongst the so-called Neglected Tropical Diseases (NTDs). S. stercoralis is a nematode, which is distributed worldwide; it has been estimated that it could affect millions of people, mainly in tropical and subtropical endemic regions. The difficulties of diagnosis lead to infection rates being underreported. Asymptomatic patients have chronic infections that can lead to severe hyperinfection...
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Feline infectious peritonitis (FIP) is an important feline viral disease, causing an overridden inflammatory response that results in a high mortality rate, primarily in young cats. Curcumin is notable for its biological activities against various viral diseases; however, its poor bioavailability has hindered its potential in therapeutic application. In this study, curcumin was encapsulated in chitosan nanoparticles to improve its bioavailability. Curcumin-encapsulated chitosan (Cur-CS) nanoparticles...
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Differential Expression and Prognostic Value of Cytoplasmic and Nuclear Cyclin D1 in Prostate Cancer
Cyclin D1 (CCND1) has been revealed as a key regulating protein in cell cycle (G1 phase) and plays a critical role in promoting tumor development. The purpose of our study was to investigate the associations between CCND1 and biochemical recurrence of prostate cancer (PCa). We performed immunostaining of CCND1 on a tissue microarray and evaluated the CCND1 expression levels based on the intensity and extent of staining. The clinical data was collected, and the follow-up data was received by searching...
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Infantile diarrhea is a serious public health problem around worldwide and results in millions of deaths each year. The levels and sources of dietary protein are potential sources of diarrhea, but the relationship between the pathogenesis causes of infantile diarrhea and protein intake remains poorly understood. Many studies have indicated that the key to understanding the relationship between the protein in the diet and the postweaning diarrhea of piglets is to explore the influences of protein...
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Background. Systemic lupus erythematosus (SLE) is a multifactorial autoimmune disease characterized by apoptotic clearance deficiency provoking autoimmune responses and leading to multiple organ damage. PPAR-δ, encoded by the PPARD gene, was induced in macrophages promoting the timely disposal of apoptotic cells. Biological studies had provided solid foundation of PPARD involvement in SLE; it is worthwhile to further explore the genetic contribution of PPARD to SLE. Methods. We performed a discovery-replication...
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The main aim of the paper was to simulate the drug release by a multifractal theoretical model, as a valuable method to assess the drug release mechanism. To do this, drug delivery films were prepared by mixing poly(vinyl alcohol boric acid) (PVAB) and diclofenac (DCF) sodium salt drug in different mass ratios from 90/10 to 70/30, in order to obtain drug delivery systems with different releasing rates. The different drug content of the three systems was confirmed by energy-dispersive spectroscopy...
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Background. Early detection is crucial for the prognosis of patients with autoimmune liver disease (AILD). Due to the relatively low incidence, developing screening tools for AILD remain a challenge. Aims. To analyze clinical characteristics of AILD patients at initial presentation and identify clinical markers, which could be useful for disease screening and early detection. Methods. We performed observational retrospective study and analyzed 581 AILD patients who were hospitalized in the gastroenterology...
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In this paper, first, we introduce a new type of fuzzy metric space which is a generalization of fuzzy metric spaces. Second, we study the topological properties of fuzzy metric spaces. Finally, we extend Kannan-type mappings to generalized Kannan-type mappings under gauge functions introduced by Fang in fuzzy metric spaces and prove the existence and uniqueness of fixed point for this kind of mappings. Furthermore, we also obtain the common fixed point theorems for weak compatibility along with...
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This paper is devoted in characterizing the central BMO space via the commutator of the fractional Hardy operator with rough kernel. Precisely, by a more explicit decomposition of the operator and the kernel function, we will show that if the symbol function belongs to the central BMO space, then the commutator are bounded on Lebesgue space. Conversely, the boundedness of the commutator implies that the symbol function belongs to the central BMO space by exploiting the center symmetry of the Hardy...
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Some basic properties in Orlicz spaces and Orlicz sequence spaces that are generated by monotone function equipped with the Mazur-Orlicz -norm are studied in this paper. We give some relationships between the modulus and the Mazur-Orlicz -norm. We obtain an interesting result that the norm of an element in line segments is formed by two elements on the unit sphere less than or equal to 1 if and only if that the monotone function is a convex function. The criterion that Orlicz spaces and Orlicz sequence...
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