! ORL via Alexandros G.Sfakianakis on Inoreader: Increased Pharyngeal Reflux in Patients Treated for Laryngeal Cancer: A Pilot Study

! ORL via Alexandros G.Sfakianakis on Inoreader

Increased Pharyngeal Reflux in Patients Treated for Laryngeal Cancer: A Pilot Study Aug 26th 2015, 05:03, by LeBlanc, B., Lewis, E., Caldito, G., Nathan, C.-A. O. Objective Laryngopharyngeal reflux may cause significant morbidity in the head and neck cancer population. The goal was to determine if pharyngeal reflux is increased as a result of treatment for laryngeal cancer. Study Design A prospective clinical trial. Setting Tertiary care center. Subjects Head and neck cancer patients treated at LSU Health–Shreveport with a plan for total laryngectomy. Methods Pharyngeal pH probes with resultant reflux scores were utilized in patients with laryngeal/pharyngeal cancer with a plan for total laryngectomy. Results Twenty-four patients were enrolled, of whom 10 underwent postlaryngectomy pH probe monitoring. The mean upright Ryan score for patients with prior radiotherapy was 238.4 (n = 8), compared with 22.0 (n = 16) in those without prior radiotherapy (P = .02). The supine score was 12.7 in the radiotherapy group and 2.7 in those without radiotherapy (P = .12). For those who completed the postlaryngectomy pH study (n = 10), the mean preoperative upright Ryan score was 106.32 ± 279.1 versus a postoperative score of 209.0 ± 352.6 (P = .04). The mean supine preoperative Ryan score in this group was 3.9 ± 3.47, as opposed to 8.1 ± 9.6 postoperatively (P = .13) Conclusions This study suggests that treatment of laryngeal cancer may increase the incidence of pharyngeal reflux. Consider screening for reflux in patients previously treated for laryngeal cancer.

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