| Ibandronate treatment of diffuse sclerosing osteomyelitis of the mandible: pain relief and insight into pathogenesis Sep 6th 2015, 02:14, by Sven Otto, Matthias Troeltzsch, Egon Burian, Salah Mahaini, Florian Probst, Christoph Pautke, Michael Ehrenfeld, Wenko Smolka Diffuse sclerosing osteomyelitis of the mandible (DSO) is a rare and poorly understood disease. Current treatment protocols, including steroid or analgesic medication and corticotomies, show poor or frustrating outcome results and are accompanied by potentially severe side effects. The aim of this study was to determine whether there is a beneficial role of infusions with nitrogen-containing bisphosphonates (ibandronate) in acute conditions of DSO. |
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