IL-17; overview and role in oral immunity and microbiome

Abstract

Interleukin-17 (IL-17) is a multifaceted cytokine with diverse roles both in immune-protection and also immunopathology. IL-17 has a well-recognized role in immune surveillance at mucosal and barrier surfaces (Miossec & Kolls, 2012, Song et al., 2016) but also has been increasingly implicated as a driver of immunopathology in settings of autoimmunity and chronic inflammation (Gaffen et al., 2014).

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