The platelet-activating factor pathway in food allergy and anaphylaxis

The synchronous release of multiple chemical mediators and their combined effects on target organs are responsible for the disruption of homeostasis seen in anaphylaxis. The exocytosis and release of these mediators collectively contribute to the multisystem manifestations of anaphylaxis, but clearly the actions of certain mediators appear to be more prominent and contribute disproportionately to severe and fatal outcomes.

http://ift.tt/2efLdP9