Cetirizine-responsive, persistent idiopathic eosinophilia in a nonatopic child

Atopy is one of the most common causes of eosinophilia in the developed world.1,2 Antihistamines have been successfully used in the treatment of atopy and associated eosinophilia.3,4 However, it is unclear whether antihistaminic therapy is effective in controlling eosinophilia in patients without associated atopy.1–4 We present a case of a nonatopic child who presented with idiopathic eosinophilia responding to antihistaminic therapy.

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