Challenges in photoprotection: Introduction

The biologic effects of ultraviolet radiation (UVR), which range from erythema, tanning, and photoaging to photocarcinogenesis, are well known to dermatologists and photobiologists. In the past few years, visible light has been shown to induce prolonged tanning response in dark-skinned individuals, which may contribute to melasma and postinflammatory hyperpigmentation frequently seen in these individuals.1 Furthermore, generation of cyclobutane-pyrimidine dimers has been shown to occur even after exposure to UVR has ended2; this has been termed "dark cyclobutane-pyrimidine dimer formation," and is associated with the presence of melanin, especially pheomelanin.

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