Low-level red LED light inhibits inflammation induced by unsaturated fatty acid in vitro

Acne vulgaris is a chronic inflammatory disease of the pilosebaceous units (PSU). Light therapy has attracted medical interest as a safe, alternative treatment for acne. Both blue and red light therapies at high doses >10 J/cm2 have demonstrated marked effects on inflammatory acne lesions. However, few studies have investigated the effects of lower doses of light. In this study, the biological effects of low red light doses were investigated using an in vitro model previously developed to mimic the inflammation, and hyperkeratinization seen clinically in acne.

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