Hydroxychloroquine as a steroid-sparing agent in an infant with chronic urticaria

Hydroxychloroquine is an antimalarial drug frequently used to reduce inflammation in autoimmune and inflammatory conditions.1,2 In adults, hydroxychloroquine can be used as an alternative agent to treat antihistamine-refractory chronic spontaneous urticaria (CSU).3 It is unknown whether hydroxychloroquine is safe and effective for treating antihistamine-refractory CSU in children. We present the case of a 9-month-old male infant with 5 months of recurrent, unprovoked hives and swelling who was treated safely and successfully with hydroxychloroquine.

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