Injectable cosmetic fillers are increasingly popular, but are not often considered as a cause of abnormal findings on imaging. We present a case of poly-L-lactic acid (PLLA) filler associated with 18-fluorodeoxyglucose (FDG) uptake, which had the potential to interfere with staging of a squamous cell carcinoma of the lateral tongue. We characterise the FDG-positron emission tomography/computed tomography (PET/CT) properties of a PLLA dermal filler, Sculptra® (Aventis), and highlight its potentially confounding appearance in the staging scans of oncological patients, particularly those with oral tumours.
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