Preclinical Randomized Controlled Trial of Bilateral Discectomy versus Bilateral Discopexy in Black Merino Sheep Temporomandibular Joint: TEMPOJIMS – phase 1- Histologic, Imaging and Body Weight results

The role of temporomandibular joint (TMJ) surgery is not well defined due to a lack of quality randomized controlled clinical trials, comparing different TMJ surgical treatments with medical and placebo interventions. The temporomandibular joint interposal study (TEMPOJIMS) is a rigorous preclinical trial divided in 2 phases. In phase 1 the authors investigated the role of the TMJ disc and in phase 2 the authors evaluated 3 different interposal materials. The present work of TEMPOJIMS - phase 1, aims to evaluate histopathologic and imaging impact of bilateral discectomy or discopexy in Black Merino sheep TMJ, using a high-quality trial following the ARRIVE guidelines.

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