High dimensional immune biomarkers demonstrate differences in phenotypes and endotypes in food allergy and asthma

Advances in high throughput technologies and big data analytics are rapidly increasing our understanding of the role of various immune cells and factors associated with atopic disease beyond the Th1/Th2 axis. Many children and adults with atopy can suffer from co-morbid conditions like having food allergy and chronic asthma, which can increase the risk of anaphylaxis and fatal reactions to a food allergen. Further understanding of the contributions and roles of the different immune cell subsets would be of great value in understanding the food allergy-asthma co-morbid clinical phenotype.

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