Outcomes in Third and Fourth Kidney Transplants Based on the Type of Donor

Background An increasing number of patients are requiring multiple retransplants. We assessed outcomes of third and fourth kidney transplants, to aid decision-making on the most suitable donor type. Methods Data were collected retrospectively for 2561 transplants, including 69 third and 8 fourth, performed from 2000-2017. Demographics and outcomes for the combined third/fourth group were compared to first and second transplants. Within the third/fourth kidney transplant group, comparisons were made between deceased-donors (n=39), live-donor-HLA-compatible (n=23) and -incompatible (n=13) transplants, as well as between standard (n=25) and extended-criteria (n=14) deceased-donor transplants. Results Patient survival did not differ significantly by transplant number (p=0.532), whilst death-censored graft survival declined progressively, from 89% at 5 years in first, 85% in second and 74% in the third/fourth transplant group (p

https://ift.tt/2Lj67uZ