Using intralesional methotrexate to treat recalcitrant cutaneous Crohn’s disease

Introduction: Cutaneous Crohn's disease (CD) is a rare, and not entirely understood, manifestation of CD that has various clinical presentations. Treatment is difficult, as methods detailed in several case reports over the decades demonstrate mixed efficacy in treating cutaneous CD. Few reports have shown promise using intralesional methotrexate. This case report describes a case of recalcitrant cutaneous CD that resolved with intralesional methotrexate.

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