“Electrochemotherapy – a loco regional therapy with well-established palliative effect in patient with large recurrent lesion of Head and Neck”

Electrochemotherapy (ECT) is a well-established treatment for cutaneous tumors consisting in the combination of electroporation and chemotherapy. Electroporation has been studied for approximately 20 years as a means of facilitating the transport of normally non-permeant molecules into cells. By applying an electric field to the cells, the membrane become permeable, allowing chemotherapic agents such as bleomycin to enter the cell.increasing its toxicity(Mir et al., 1991).

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