A CASE OF NON-IMMUNOLOGIC ANAPHYLAXIS TO N-ACETYLCYSTEINE IN A PATIENT WHO OVERDOSED ON ACETAMINOPHEN

Management of acetaminophen toxicity typically involves administering N-acetylcysteine (NAC) in order to prevent hepatic injury. While NAC is considered the gold standard of therapy, it is also associated with risk of non-immunologic anaphylaxis. This case illustrates a less commonly recognized reaction to NAC and provides an opportunity to review management of acetaminophen toxicity in patients who demonstrate such a reaction.

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