European Journal of Cancer Supplements
Alexandros G. SfakianakisστοΟγκολογίαΠριν από 14 δευτερόλεπτα
Title page 1 Publication date: November 2015 *Source:*European Journal of Cancer Supplements, Volume 13, Issue 1 Title page 2 Publication date: November 2015 *Source:*European Journal of Cancer Supplements, Volume 13, Issue 1 Letter of Welcome Publication date: November 2015 *Source:*European Journal of Cancer Supplements, Volume 13, Issue 1 Acknowledgments Publication date: November 2015 *Source:*European Journal of Cancer Supplements, Volume 13, Issue 1 P28 Publication date: November 2015 *Source:*European Journal of Cancer Supplements, Volume 13, Issue...περισσότερα »
Upper airway dimensions in patients undergoing orthognathic surgery
Alexandros G. SfakianakisστοΚοσμητική ΟδοντοΙατρική και ΓναθοΧειρουργικήΠριν από 26 δευτερόλεπτα
Upper airway dimensions in patients undergoing orthognathic surgery: a systematic review and meta-analysis: The objective of this systematic review was to evaluate the effect of different types of orthognathic surgery on the dimensions of the upper airways assessed using three-dimensional images. An electronic search was performed in Cochrane Library, Medline, Scopus, VHL, Web of Science, and the System for Information on Grey Literature in Europe, ending January 2015. Inclusion criteria encompassed clinical studies in humans, patient age >15 years, patients submitted to maxillary o... περισσότερα »
Underestimation of prevalence of raised blood sugar from history compared to biochemical estimation: support for the WHO rule of halves in a population based survey in Eritrea of 2009
Αλέξανδρος ΣφακιανάκηςστοMedicine by Alexandros G.SfakianakisΠριν από 32 δευτερόλεπτα
To ascertain the prevalence of diabetes mellitus from history and biochemical estimation so as to attest the WHO Rule of halves in a lean population. A population based national survey on diabetes mellitus was carried out in 2009. History and fingerpicks blood analysis were examined according to recommended procedures of the WHO STEPwise approach and the WHO recommended automated machine to compare the two modalities of estimating diabetes prevalence. Over 6000 people with a response rate of 95 % and a prevalence of raised blood glucose of 5.0 %. The prevalence from history of rai...περισσότερα »
Effects of dietary allspice, Pimenta dioica powder on physiological responses of Oreochromis mossambicus under low pH stress
Αλέξανδρος ΣφακιανάκηςστοMedicine by Alexandros G.SfakianakisΠριν από 32 δευτερόλεπτα
This study investigated the effects of the supplementation with allspice (0, 5, 10, 15, or 20 g kg −1 ) on the haemato-immunological and biochemical variables in tilapia, Oreochromis mossambicus under acidic stress condition. In a 60-day feeding trial, 15 aquariums (80-L) were stocked with 18 fish (20.05 ± 0.10 g) each. Then, acidic stress was achieved by exposing the sampled fish to acidic water (pH 5.5) for 3 days. Allspice supplementation influenced the haematological indices, serum glucose, protein, globulin and innate immune parameters such as respiratory burst activity, lyso...περισσότερα »
Almost automorphic solutions for shunting inhibitory cellular neural networks with time-varying delays
Αλέξανδρος ΣφακιανάκηςστοMedicine by Alexandros G.SfakianakisΠριν από 32 δευτερόλεπτα
This paper is concerned with the shunting inhibitory cellular neural networks with time-varying delays. Under some suitable conditions, we establish some criteria on the existence and global exponential stability of the almost automorphic solutions of the networks. Numerical simulations are given to support the theoretical findings.Mathematics Subject Classification: 39A60, 39A12. from #Medicine via ola Kala on Inoreader http://ift.tt/1Np74BO via IFTTT
Impact evaluation and association with EuroQol 5D health-related utility values in Ménière’s disease
Αλέξανδρος ΣφακιανάκηςστοMedicine by Alexandros G.SfakianakisΠριν από 32 δευτερόλεπτα
The study was aimed at evaluating the validity of impact measures among patients with Ménière's disease (MD) with outcome variables of EuroQol generic health-related quality of life (HRQoL) measures (i.e., EQ-5D) by using Visual Analogue Scale (VAS) and EQ-5D index values. 183 members (out of 200 contacted) of the Finish Ménière Association returned the questionnaires that they had filled out. Various open-ended and structured questionnaires focusing on diagnostic aspects of symptoms and impairment caused by the disease were used. For activity limitation and participation restrict... περισσότερα »
Stability of treatments for recurrent temporomandibular joint luxation
Alexandros G. SfakianakisστοΚοσμητική ΟδοντοΙατρική και ΓναθοΧειρουργικήΠριν από 58 δευτερόλεπτα
Stability of treatments for recurrent temporomandibular joint luxation: a systematic review: Temporomandibular joint luxation (TMJ) is the excessive anterior translation of the mandibular condyle out of its normal range of movement and away from the glenoid fossa. Once dislocation occurs, the abnormal condylar position generates reflex contractions of the masticatory muscles, which in turn hinder movement of the condyle back to its resting position. Frequent luxation episodes characterize a condition referred to as recurrent TMJ luxation. While there are several surgical and conserv... περισσότερα »
Three-Dimensional Printing Technology for Medial Orbital Wall Fractures
Alexandros G. SfakianakisστοΚοσμητική ΟδοντοΙατρική και ΓναθοΧειρουργικήΠριν από 58 δευτερόλεπτα
Three-Dimensional Printing Technology for Medial Orbital Wall Fractures: [image: image]
Deep Venous Thrombosis in Teen With Crouzon Syndrome Post-Le Fort III Osteotomy With Rigid External Distraction
Alexandros G. SfakianakisστοΚοσμητική ΟδοντοΙατρική και ΓναθοΧειρουργικήΠριν από 58 δευτερόλεπτα
Deep Venous Thrombosis in Teen With Crouzon Syndrome Post-Le Fort III Osteotomy With Rigid External Distraction: Abstract: Venous thromboembolic events are rare in pediatric patients. Risk factors associated with the development of venous thromboembolic events in pediatric patients include the use of central venous catheters, hospitalization, cancer, sepsis, trauma, surgery, and congenital prothrombotic disorders. The authors present the case of a 14-year-old man with Crouzon syndrome who required Le Fort III osteotomy with rigid external distraction for significant midface hypopla...περισσότερα »
Comparative Analysis of Bilateral Temporomandibular Joints in Patients With Unilateral Temporomandibular Joint Complaints Using Cone Beam Computed Tomography
Alexandros G. SfakianakisστοΚοσμητική ΟδοντοΙατρική και ΓναθοΧειρουργικήΠριν από 58 δευτερόλεπτα
Comparative Analysis of Bilateral Temporomandibular Joints in Patients With Unilateral Temporomandibular Joint Complaints Using Cone Beam Computed Tomography: [image: image]Objective: This study was to determine if there was any temporomandibular joint (TMJ) indicator that was not statistically different in the controls but was with statistical difference between the bilateral sides in patients with unilateral TMJ complaints using cone beam computed tomography (CBCT). Methods: TMJ CBCT images of 123 patients were used to preliminarily determine the indicators suitable for the measuri... περισσότερα »
Maxillary Segmental Micro Osteotomy: A Human Cadaver Study on the Efficacy of the Technique
Alexandros G. SfakianakisστοΚοσμητική ΟδοντοΙατρική και ΓναθοΧειρουργικήΠριν από 58 δευτερόλεπτα
Maxillary Segmental Micro Osteotomy: A Human Cadaver Study on the Efficacy of the Technique: [image: image]Purpose: Ultrasonic bone cutting was recently introduced as a feasible alternative to the conventional tools of cranio-maxillofacial surgery because it offers improved precision and safety. This study examined the feasibility of minimally invasive orthodontic or preprosthetic surgery using a piezosurgery device for latero-posterior maxillary segmental osteotomy. Materials and Methods: Four fresh cadaveric heads were obtained for this study. Maxillary posterior osteotomy was perf... περισσότερα »
The Paradoxical Predominance of Medial Wall Injuries in Blowout Fracture
Alexandros G. SfakianakisστοΚοσμητική ΟδοντοΙατρική και ΓναθοΧειρουργικήΠριν από 58 δευτερόλεπτα
The Paradoxical Predominance of Medial Wall Injuries in Blowout Fracture: [image: image]Purpose: To evaluate the type and cause of orbital blowout fractures in Korea. Design: Retrospective, observational case series. Methods: Patients who underwent reconstruction for blowout fracture from March 2004 to April 2013 at Korea University Guro and Ansan Hospitals were included in this study. Patient demographics and orbital computed tomography (CT) scans were reviewed. On CT, ethmoid air cell septa, blowout fracture type, and other combined fractures were analyzed. Blowout fracture was cla...περισσότερα »
The Precise Repositioning Instrument for Genioplasty
Alexandros G. SfakianakisστοΚοσμητική ΟδοντοΙατρική και ΓναθοΧειρουργικήΠριν από 58 δευτερόλεπτα
The Precise Repositioning Instrument for Genioplasty: [image: image]Abstract: To improve the surgical precision of genioplasty, the authors develop and validate the precise repositioning instrument for genioplasty, which can guide the precise repositioning of chin bone segment truncated during genioplasty. The patent application for the precise repositioning instrument for genioplasty is already submitted (Patent No. 201410032051. 2, China). The accuracy of genioplasty can be improved significantly by using the precise repositioning instrument to locate the chin bone segment truncat... περισσότερα »
Volumetric-Modulated Arc Beam Radiosurgery of Multiple Brain Metastases
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 1 ώρα
Normal Brain Sparing With Increasing Number of Beams and Isocenters in Volumetric-Modulated Arc Beam Radiosurgery of Multiple Brain Metastases: Recent studies have reported about the application of volumetric-modulated arc radiotherapy in the treatment of multiple brain metastases. One of the key concerns for these radiosurgical treatments lies in the integral dose within the normal brain tissue, as it has been shown to increase with increasing number of brain tumors treated. In this study, we investigate the potential to improve normal brain tissue sparing specific to volumetric-m... περισσότερα »
Impact of whole-body MRI in a general population study
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 1 ώρα
Impact of whole-body MRI in a general population study: AbstractThis study examined the long-term impact of whole-body MRI and the disclosure of incidental findings on quality of life (QoL) and depressive symptoms in a general population cohort. Analyses were conducted among 4420 participants of the Study of Health in Pomerania SHIP-Trend cohort, of which 2188 received a whole-body MRI examination. A 2.5-year postal follow-up of SHIP-Trend (response: 86 %) included the Short Form Health Survey (SF-12), based on which the Mental Health Component Summary Score (MCS), and Physical Hea... περισσότερα »
Eustachian Tube as a Landmark to the Internal Carotid Artery in Endoscopic Skull Base Surgery
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 1 ώρα
Eustachian Tube as a Landmark to the Internal Carotid Artery in Endoscopic Skull Base Surgery: Objective The purpose of this study was to probe the relationship between the eustachian tube and the internal carotid artery in skull base surgery by an intranasal endoscopic approach. Study Design Cadaver study and illustrative cases. Setting Minimally invasive surgery laboratory and operating room. Subjects and Methods A series of 5 cadaveric heads were dissected to elaborate on the relevant surgical anatomy about the eustachian tube and the internal carotid artery. Three cases were... περισσότερα »
Postoperative Complications in Elderly Patients Undergoing Head and Neck Surgery
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 1 ώρα
Postoperative Complications in Elderly Patients Undergoing Head and Neck Surgery: Opportunities for Quality Improvement: Objective To assess the frequency and nature of postoperative complications that occur in elderly patients, as compared with younger patients, following head and neck surgery. Study Design Cohort study of national database. Setting American College of Surgeons National Surgical Quality Improvement Program from 2005 to 2013. Subjects and Methods We identified 29,891 patients who had head and neck surgery during the study period and classified them as having upp...περισσότερα »
4D MRI for the Localization of Parathyroid Adenoma
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 1 ώρα
4D MRI for the Localization of Parathyroid Adenoma: A Novel Method in Evolution: The sestamibi scan (MIBI) and ultrasound (US) are used for preoperative localization of parathyroid adenoma (PTA), with sensitivity as high as 90%. We developed 4-dimensional magnetic resonance imaging (4D MRI) as a novel tool for identifying PTAs. Eleven patients with PTA were enrolled. 4D MRI from the mandible to the aortic arch was used. Optimization of the timing of image acquisition was obtained by changing dynamic and static sequences. PTAs were identified in all except 1 patient. In 9 patients, ...περισσότερα »
The Usefulness of Preoperative Thyroid-Stimulating Hormone for Predicting Differentiated Thyroid Microcarcinoma
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 1 ώρα
The Usefulness of Preoperative Thyroid-Stimulating Hormone for Predicting Differentiated Thyroid Microcarcinoma: Objective Thyroid-stimulating hormone (TSH) is a known thyroid growth factor, but the pathogenic role of TSH in thyroid tumorigenesis is controversial. The aim of this study is to examine the relationship between preoperative TSH and differentiated thyroid microcarcinoma (DTMC). Data Sources We searched PubMed, EMBASE, Ovid, Web of Science, and the Cochrane Library from their inception to March 2015 and performed a systematic literature review of original studies. Revie... περισσότερα »
Corpus Callosotomy for Patients With Intractable Seizures
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 1 ώρα
Corpus Callosotomy for Patients With Intractable Seizures: An Insight Into the Rapid Relapse: It is well known that corpus callosotomy (CC) can bring a favorable seizure control outcome for disabling generalized seizures, but the complete remission rate achieved by CC is rarely reported, and the postoperative relapse pattern is still not clear. In this study, the authors reviewed patients with medically refractory epilepsy who were suffering disabling seizures, including drop attacks, generalized tonic–clonic seizures (GTCS), tonic seizures, atonic seizures, atypical absences, and c... περισσότερα »
Image-Guided Endoscopic Combined With Deep Lateral Orbitotomy Removal of a Small Foreign Body at the Deep Lateral Orbital Apex
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 1 ώρα
Image-Guided Endoscopic Combined With Deep Lateral Orbitotomy Removal of a Small Foreign Body at the Deep Lateral Orbital Apex: [image: image]Abstract: To remove a small foreign body located at the deep orbit apex presents an extremely challenging problem. Small foreign bodies located in shallow lateral orbital and nasal orbital apex have been reported successfully removing in endoscopic surgery with the help of surgical navigation system. Here, the authors first describe successfully removal of a small foreign body at the deep lateral orbital apex with the help of image-guided endo...περισσότερα »
Reconstruction of Facial Defect Using Deltopectoral Flap
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 1 ώρα
Reconstruction of Facial Defect Using Deltopectoral Flap: [image: image]Abstract: Reconstruction of the head and neck is a challenge for otolarygology surgeons, maxillofacial surgeons as well as plastic surgeons. Defects caused by the resection and/or trauma should be closed with flaps which match in color, texture and hair bearing characteristics with the face. Deltopectoral flap is a one such flap from chest and neck skin mainly used to cover the facial defects. This study report a patient presenting with tragic Road Traffic Accident (RTA) admitted to maxillofacial surgery departm... περισσότερα »
Change in the Upper Airway of Patients With Obstructive Sleep Apnea Syndrome Using Computational Fluid Dynamics Analysis: Conventional Maxillomandibular Advancement Versus Modified Maxillomandibular Advancement With Anterior Segmental Setback Osteotomy
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 1 ώρα
Change in the Upper Airway of Patients With Obstructive Sleep Apnea Syndrome Using Computational Fluid Dynamics Analysis: Conventional Maxillomandibular Advancement Versus Modified Maxillomandibular Advancement With Anterior Segmental Setback Osteotomy: Objective: The aim of the study was to compare the effect of conventional maxillomandibular advancement (MMA) and modified MMA with anterior segmental setback osteotomy (MMA-ASSO) on the airway changes in patients with obstructive sleep apnea syndrome (OSAS) using three-dimensional computational fluid dynamics (3D-CFD) analysis. Meth... περισσότερα »
Anatomic Study of Posterior Communicating Artery in Computed Tomographic Image
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 1 ώρα
Anatomic Study of Posterior Communicating Artery in Computed Tomographic Image: [image: image]Purpose: This study aims to provide an anatomic data of posterior communicating artery (PComA) and its anatomic relationship to the adjacent structures, so as to guide surgeons in the surgery of internal carotid artery–posterior communicating artery aneurysm clipping and sellar tumors resection without injuring the PComA. Methods: Computer topographic angiography images of 123 individuals were reviewed, and the measurements were done on coronal, sagittal, axial, and other user-defined planes...περισσότερα »
Customized Titanium Mesh for Repairing Cranial Defects: A Method With Comprehensive Evaluation
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 1 ώρα
Customized Titanium Mesh for Repairing Cranial Defects: A Method With Comprehensive Evaluation: Abstract: Titanium cranioplasty is one of the well-established and widely used techniques for repairing cranial defects. In this paper, we present an improved way to design and create titanium meshes with more evaluation process. Computed tomography scan data of patients were used to create three-dimensional virtual models. Implants were designed with NX ImageWare 13.2 (Siemens PLM Software, Plano, TX).1 Final titanium meshes were assessed by Geomagic Studio 12 (Geomagic, Inc., Morrisvill...περισσότερα »
A Novel System for Navigation–and Robot-Assisted Craniofacial Surgery: Establishment of the Principle Prototype
Alexandros G. SfakianakisστοΚοσμητική ΟδοντοΙατρική και ΓναθοΧειρουργικήΠριν από 1 ώρα
A Novel System for Navigation–and Robot-Assisted Craniofacial Surgery: Establishment of the Principle Prototype: [image: image] Purpose: The authors aimed to develop 1 novel navigation-guided robotic system for craniofacial surgery to improve accuracy during operation. Materials and Methods: A new 7-DOF (7-degree-of-freedom) robotic arm was designed and manufactured. Based on our self-developed navigation system TBNAVIS-CMFS, the key technique of integration was studied. A phantom skull model was manufactured based on computed tomography image data and used for the preexperimental s... περισσότερα »
A Novel Technique Using Customized Headgear for Fixation of Rigid External Distraction Device in an Infant With Crouzon Syndrome
Alexandros G. SfakianakisστοΚοσμητική ΟδοντοΙατρική και ΓναθοΧειρουργικήΠριν από 1 ώρα
A Novel Technique Using Customized Headgear for Fixation of Rigid External Distraction Device in an Infant With Crouzon Syndrome: [image: image]Abstract: Rigid external distraction device is often indicated for superior midfacial advancement in pediatric syndromic craniosynostosis patients. Even though the technique is proven reliable to treat the functional issues related to the craniofacial deformity, major complications associated with its fixation, such as intracranial pin perforation and migration have been reported. We report a novel technique of using a customized headgear to ... περισσότερα »
Endoscopy-Assisted Single-Incision Technique to Harvest the Conchal Cartilage and Temporal Fascia Simultaneously by Using Phaco Slit Knife
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 1 ώρα
Endoscopy-Assisted Single-Incision Technique to Harvest the Conchal Cartilage and Temporal Fascia Simultaneously by Using Phaco Slit Knife: [image: image]Abstract: Conchal cartilage and temporal fascia grafts are useful materials for secondary rhinoplasty cases. Generally, surgeons require to access autologous grafts fast and effortlessly. Harvesting 2 different types of graft, such as cartilage and fascia, however, are associated with limitations, such as additional surgery time, extra incisions, and postoperative additional distortions at the graft–host interface. The authors evol... περισσότερα »
Foreign Body Mimicking a Dental Implant Radiographically
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 1 ώρα
Foreign Body Mimicking a Dental Implant Radiographically: [image: image] Abstract: Foreign bodies are often encountered in the maxillofacial region and can present in several ways. They frequently occur as a result of accidents, explosions, and gunshot injuries or because of iatrogenic factors in therapeutic interventions in daily dental practice. This report describes an unusual case of a broken elevator blade mimicking a dental implant embedded in alveolar bone radiographically, within the maxillary palatal mucosa during a traumatic maxillary right first molar extraction.
Reconstruction of Inferior Orbital Wall Fractures Using Bone Fragments
Alexandros G. SfakianakisστοΚοσμητική ΟδοντοΙατρική και ΓναθοΧειρουργικήΠριν από 1 ώρα
Reconstruction of Inferior Orbital Wall Fractures Using Bone Fragments: [image: image]Introduction: Various materials have been used as implants in orbital floor fractures. The fractured bone fragments, however, are not usually used because of their small size and delicate characteristics. To overcome this limitation, the authors used autologous bone fragments combined with fibrin glue and an absorbable plate to repair inferior orbital wall fractures. Methods: Thirty-four patients with orbital floor fractures treated in a single center from January 2013 to September 2014 were prospec... περισσότερα »
Comparative Analysis Between Computed and Conventional Inferior Alveolar Nerve Block Techniques
Alexandros G. SfakianakisστοΚοσμητική ΟδοντοΙατρική και ΓναθοΧειρουργικήΠριν από 1 ώρα
Comparative Analysis Between Computed and Conventional Inferior Alveolar Nerve Block Techniques: [image: image] Objective: The aim of this randomized, double-blind, controlled trial was to compare the computed and conventional inferior alveolar nerve block techniques in symmetrically positioned inferior third molars. Patients and Methods: Both computed and conventional anesthetic techniques were performed in 29 healthy patients (58 surgeries) aged between 18 and 40 years. The anesthetic of choice was 2% lidocaine with 1: 200,000 epinephrine. The Visual Analogue Scale assessed the pa...περισσότερα »
Milestones Contributing to the Evolution of Craniofacial Surgery
Alexandros G. SfakianakisστοΚοσμητική ΟδοντοΙατρική και ΓναθοΧειρουργικήΠριν από 1 ώρα
Milestones Contributing to the Evolution of Craniofacial Surgery: [image: image]Abstract: Craniofacial surgery (CFS) has a rich history of collaboration with a wide variety of surgical and nonsurgical specialties. This has resulted in a large volume of publications across this spectrum of subspecialties cataloging the advancements across the field. The authors aim to analyze the characteristics of the most cited articles in CFS. A literature search was performed using the Thomson/Reuters Web of Knowledge database to identify the top 50 most cited articles in CFS. The articles were a... περισσότερα »
Surgery Versus Nonsurgery Option for Scissors Bite Treatment
Alexandros G. SfakianakisστοΚοσμητική ΟδοντοΙατρική και ΓναθοΧειρουργικήΠριν από 1 ώρα
Surgery Versus Nonsurgery Option for Scissors Bite Treatment: [image: image] Background: This article compared the use of temporary skeletal anchorage devices (TSADs) and orthognathic surgery for scissors bite correction. Methods: To correct the scissors bite without orthognathic surgery, a cross-type titanium miniplate was placed with 3 miniscrews (1.5 mm in diameter and 5 mm in length) in the midpalatal area, without a surgical incision and under local anesthesia. In addition, a 1 miniscrew was placed on the buccal alveolar bone to avoid molar extrusion during uprighting. In the s... περισσότερα »
Fabrication of Patient Specific Titanium Implants for Correction of Cranial Defects: A Technique to Improve Anatomic Contours and Accuracy
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 1 ώρα
Fabrication of Patient Specific Titanium Implants for Correction of Cranial Defects: A Technique to Improve Anatomic Contours and Accuracy: [image: image]Abstract: Hard tissue cranial defects may result from traumatic or iatrogenic etiology and warrants adequate reconstruction to provide protection to the underlying brain and cosmesis. Various techniques have been described in the literature for fabrication of patient specific titanium cranial implants. The process of fabrication of titanium patient specific implants (PSI) can be broadly classified into indirect and direct technique...περισσότερα »
Cleft and Craniofacial Care in Palestine: Breaking From the Cycle of the Past
Alexandros G. SfakianakisστοΚοσμητική ΟδοντοΙατρική και ΓναθοΧειρουργικήΠριν από 1 ώρα
Cleft and Craniofacial Care in Palestine: Breaking From the Cycle of the Past: [image: image] Abstract: The history of cleft care in the Palestinian territories has largely been sporadic and dependent on foreign practitioners. This article discusses the recent history and the current status of cleft care in Palestine, including the quality of training among Palestinian cleft practitioners and limitations in operating room capacity. The discussion concludes with a future model of cleft care that focuses on carefully crafted programs to train surgeons (this is broadly applicable to o... περισσότερα »
Severe Agnathia–Otocephaly Complex: Surgical Management and Longitudinal Follow-up From Birth Through Adulthood
Alexandros G. SfakianakisστοΚοσμητική ΟδοντοΙατρική και ΓναθοΧειρουργικήΠριν από 1 ώρα
Severe Agnathia–Otocephaly Complex: Surgical Management and Longitudinal Follow-up From Birth Through Adulthood: [image: image]Abstract: Agnathia-otocephaly complex (AOC) is characterized by mandibular hypo- or aplasia, ear abnormalities, microstomia, and microglossia. Though rare and often fatal, this is the first report detailing various reconstructive strategies beyond infancy as well as longitudinal follow-up into adulthood. All patients with AOC treated at our institution over a 30 year period were reviewed. Four patients were identified, one with agnathia, one with micrognathia...περισσότερα »
Three-Dimensional Soft Tissue Assessment Following Mandibular Bilateral Sagittal Split Osteotomy
Alexandros G. SfakianakisστοΚοσμητική ΟδοντοΙατρική και ΓναθοΧειρουργικήΠριν από 1 ώρα
Three-Dimensional Soft Tissue Assessment Following Mandibular Bilateral Sagittal Split Osteotomy: [image: image]Purpose: The purpose of the study is to quantify anteroposterior and transverse facial soft tissue changes with respect to underlying skeletal movements after bilateral sagittal split osteotomy by using cone beam computed tomography (CBCT). Patients and Methods: The study was conducted on 6 patients who required bilateral sagittal split osteotomy for correction of mandibular retrognathism. The patients were scanned using CBCT 1 week preoperatively, and 6 months postoperativ... περισσότερα »
Frontorbital Fibrous Dysplasia Resection and Reconstruction With Custom Polyetherlatone Alloplast
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 1 ώρα
Frontorbital Fibrous Dysplasia Resection and Reconstruction With Custom Polyetherlatone Alloplast: [image: image]Abstract: Fibrous dysplasia (FD) is a benign, pathological development of bone. Craniofacial bones are the most commonly involved and can potentially cause visual disturbance, proptosis, orbital dystopia, and facial deformity. This case involves a 13-year-old girl with significant proptosis (20 mm left, 17.5 mm right) and downward displacement of the left globe (1.5 mm) due to fibrous dysplasia. Reconstruction was performed with computed tomography-derived and 3D printed ...περισσότερα »
An Analysis of Surgical Treatment Results of Patients With Tympanosclerosis
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 1 ώρα
An Analysis of Surgical Treatment Results of Patients With Tympanosclerosis Abstract Objective: The authors aimed to evaluate the intraoperative features and the results of postoperative hearing gain successes of patients with tympanosclerosis who were treated surgically in our clinic. Material and Methods: A retrospective analysis was conducted on 151 ears with tympanosclerosis of 138 patients who operated because of chronic otitis media or only tympanosclerosis, between January 2007 and June 2014. They were evaluated by appealing complain, complain duration, accompanying systemic d... περισσότερα »
Endoscopic and Conventional Open Thyroidectomy for Benign Thyroid Nodules
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 1 ώρα
Surgical Outcomes Comparison Between Endoscopic and Conventional Open Thyroidectomy for Benign Thyroid Nodules: Background: The aim of this study was to compare the surgical outcomes of endoscopic thyroidectomy (ET) and conventional open thyroidectomy (COT) for benign thyroid nodules. Methods: Between March 2001 and November 2014, 224 patients underwent ET via the breast approach and 218 patients underwent COT. Clinicopathological characteristics and surgical outcomes were retrospectively compared. Results: The operation time was significantly longer in the ET group than in the COT ... περισσότερα »
Microtia Combined With Split Sole of Feet, Deformed Middle Fingers and Café -au-lait Spots on the Trunk: A New Association
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 1 ώρα
Microtia Combined With Split Sole of Feet, Deformed Middle Fingers and Café -au-lait Spots on the Trunk: A New Association: [image: image] Abstract: Microtia is a spectrum of congenital deformities. Approximately, half of the patients are associated with hemifacial microtia. The birth rate of microtia ranges from 2 per 10,000 to 17.4 per 10,000.1 Microtia and limb deformities sometimes occurred simultaneously as described in the literature. In this report, the patient was found to be with unilateral microtia combined with bilateral split sole of feet, deformed middle fingers on bot... περισσότερα »
Microvascular Decompression for Trigeminal Neuralgia: Zone Exploration and Decompression Techniques
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 1 ώρα
Microvascular Decompression for Trigeminal Neuralgia: Zone Exploration and Decompression Techniques: [image: image]Objective: The aim of this study is to introduce zone exploration of the trigeminal nerve and decompression techniques for different types of vasculars. Methods: The trigeminal nerve was sectioned into 5 zones. Zone 1, 2, 3, 4 was located at the rostral, caudal, ventral, and dorsal part of the nerve root entry zone (REZ) respectively, and zone 5 was located at the distal of the nerve root. This study contained 86 patients with trigeminal neuralgia underwent microvascular...περισσότερα »
Congenital Sialolipoma in an Infant
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 1 ώρα
Congenital Sialolipoma in an Infant: [image: image] Abstract: Sialolipoma is a newly recognized tumor of the major and minor salivary glands and represents only 0.3% of all salivary gland tumors. Only 3 cases of congenital sialolipoma are available in the literature. In the current case, we performed a total parotidectomy with facial nerve preservation on a 12-week-old infant exhibiting huge mass in the parotid region. Histopathology results showed sialolipoma. There was no recurrence at the 18-month follow-up. Although it is a very rare disease in infants, congenital sialolipoma s... περισσότερα »
Leproma Presenting as a Nasal Cavity Mass
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 1 ώρα
Leproma Presenting as a Nasal Cavity Mass: [image: image]Abstract: Leprosy is a rare disease and unfamiliar to many people. A 55-year-old woman was presented to our hospital complaining of nasal obstruction and anosmia. Nasal endoscopic examination revealed reddish-colored exophytic, nonulcerative masses in both nasal cavities. The authors performed endoscopic sinus surgery which involved endoscopic mass removal and synechiolysis. A biopsy sample stained with acid-fast stain and a rapid silver stain showed numerous filamentous organisms infiltrating macrophages, consistent with lepr... περισσότερα »
Infant Fibrolipoma Mimicking Hemangioma in Neck Region
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 1 ώρα
Infant Fibrolipoma Mimicking Hemangioma in Neck Region: [image: image] Abstract: Fibrolipoma is an extremely rare variant of lipoma. And it usually presents clinically as a slowly growing mass with a firm or soft consistency and usually occurs in middle-aged person. The authors report an unusual case of infant fibrolipma with fast-growing speed, which was misdiagnosis and mistreatment as hemangioma in local hospital. The diagnosis of hemangioma was ruled out by fine-needle aspiration cytology in authors’ hospital. Operation was performed in authors’ hospital and the prognosis of fi... περισσότερα »
Effects of Obstructive Sleep Apnea in Children as a Result of Adenoid and/or Adenotonsillar Hypertrophy on Maternal Psychologic Status
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 1 ώρα
Effects of Obstructive Sleep Apnea in Children as a Result of Adenoid and/or Adenotonsillar Hypertrophy on Maternal Psychologic Status: Abstract: The authors aimed to evaluate the effects of obstructive sleep apnea in children as a result of adenoid and/or adenotonsillar hypertrophy on maternal psychologic status. The study sample comprised the mothers of 66 children aged 3 to 15 years (mean age: 7.55 ± 2.94 years) who were scheduled to undergo curette adenoidectomy or adenotonsillectomy because of airway obstruction. The mothers completed the 14-item Hospital Anxiety and Depression...περισσότερα »
The Association Between Sleep Bruxism, Low Quality of Sleep, and Degenerative Changes of the Temporomandibular Joint
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 1 ώρα
A Study of the Association Between Sleep Bruxism, Low Quality of Sleep, and Degenerative Changes of the Temporomandibular Joint: Abstract: The aim of this study was to evaluate the presence of degenerative bone changes of the temporomandibular joint (TMJ) in individuals suffering from sleep bruxism (SB), associating these characteristics with the quality of sleep. For this, we followed the International Classification of Sleep Disorders for the diagnosis of SB, in addition to the Research Diagnostic Criteria for Temporomandibular Disorders (RDC/TMD) for the classification of TMD and ...περισσότερα »
Surgical Treatment of Pediatric Craniofacial Fractures: A National Perspective
Alexandros G. SfakianakisστοΚοσμητική ΟδοντοΙατρική και ΓναθοΧειρουργικήΠριν από 1 ώρα
Surgical Treatment of Pediatric Craniofacial Fractures: A National Perspective: Introduction: Head trauma is the most common cause of death because of injury in children, and trauma alone is the leading cause of morbidity and mortality in pediatrics. This study aimed to characterize the demographics and economic burden associated with the surgical and nonsurgical repair of craniofacial fractures in the pediatric inpatient population in the United States. Methods: A retrospective cohort study was performed using the 2012 Kids’ Inpatient Database which identified 20,070 patients who ... περισσότερα »
Analysis of Pediatric Maxillofacial Fractures Requiring Operative Treatment: Characteristics, Management, and Outcomes
Alexandros G. SfakianakisστοΚοσμητική ΟδοντοΙατρική και ΓναθοΧειρουργικήΠριν από 1 ώρα
Analysis of Pediatric Maxillofacial Fractures Requiring Operative Treatment: Characteristics, Management, and Outcomes: [image: image] Abstract: Maxillofacial fractures in pediatric trauma patients require significant force and frequently are associated with concomitant injuries. The anatomic and developmental differences between the adult and child that impact patterns of injury also affect management and outcomes. The aim of this study was to analyze fracture location, mechanism, concomitant injuries as well as methods of surgical treatment and outcomes, to improve management of ...περισσότερα »
Leading Experts in the Treatment of Congenital Cleft and Craniofacial Anomalies
Alexandros G. SfakianakisστοΚοσμητική ΟδοντοΙατρική και ΓναθοΧειρουργικήΠριν από 1 ώρα
The Public Recognizes Plastic Surgeons as Leading Experts in the Treatment of Congenital Cleft and Craniofacial Anomalies: Objective: The aim of this study is to assess the public perception of plastic surgeons (PS) as craniofacial surgery specialists. Methods: Members of the public (N = 1514) were asked to choose 1 or 2 specialists that they perceived to be an expert for 13 craniofacial surgery-related scenarios. Response patterns were distributed as “plastic surgeon alone” (PS alone), “PS combined with other specialists”, or “no plastic surgeon” (No PS). Sociodemographic data, pre...περισσότερα »
Postsurgical Relapse in Class III Patients Treated With Two-Jaw Surgery: Conventional Three-Stage Method Versus Surgery-First Approach
Alexandros G. SfakianakisστοΚοσμητική ΟδοντοΙατρική και ΓναθοΧειρουργικήΠριν από 1 ώρα
Postsurgical Relapse in Class III Patients Treated With Two-Jaw Surgery: Conventional Three-Stage Method Versus Surgery-First Approach: [image: image]Abstract: The aim of this study was to investigate the pattern, amount, and distribution of postsurgical relapse in skeletal Class III patients treated with two-jaw surgery (TJS) using conventional three-stage method (CTM) and surgery-first approach (SFA). A total of 38 patients who underwent the nonextraction approach and TJS (LeFort I posterior impaction and mandibular setback) were divided into CTM and SFA groups (all n = 19/group)....περισσότερα »
Simultaneous Correction of Temporomandibular Joint Ankylosis and Secondary Dentofacial Deformities in Adult Patients: Surgical Technique, Treatment Outcomes, and a Consideration of the Factors Involved
Alexandros G. SfakianakisστοΚοσμητική ΟδοντοΙατρική και ΓναθοΧειρουργικήΠριν από 1 ώρα
Simultaneous Correction of Temporomandibular Joint Ankylosis and Secondary Dentofacial Deformities in Adult Patients: Surgical Technique, Treatment Outcomes, and a Consideration of the Factors Involved: [image: image]Background: Temporomandibular joint (TMJ) ankylosis causes serious problems in oral functions. When it occurs in childhood, it can cause secondary dentofacial deformities. This study described our experience in the simultaneous correction of TMJ ankylosis and secondary dentofacial deformities performed in a single operation. Methods: Twenty-seven patients with TMJ ankylo... περισσότερα »
Comparative Finite Element Analysis of Short Implants and Lateralization of the Inferior Alveolar Nerve With Different Prosthesis Heights
Alexandros G. SfakianakisστοΚοσμητική ΟδοντοΙατρική και ΓναθοΧειρουργικήΠριν από 1 ώρα
Comparative Finite Element Analysis of Short Implants and Lateralization of the Inferior Alveolar Nerve With Different Prosthesis Heights: [image: image] Abstract: The lateralization of the inferior alveolar nerve (LIAN) and short implants are efficient options for rehabilitation of the posterior atrophic mandible. However, the loss of bone leads to prosthesis with greater height and lever effect that in turn can have different impact on treatments. Through the finite element method, the present study tests the hypothesis that conventional implants placed under LIAN and short implan... περισσότερα »
Residents’ Perceptions of Plastic Surgeons as Craniofacial Surgery Specialists
Alexandros G. SfakianakisστοΚοσμητική ΟδοντοΙατρική και ΓναθοΧειρουργικήΠριν από 1 ώρα
Residents’ Perceptions of Plastic Surgeons as Craniofacial Surgery Specialists: Objective: To assess residents’ perceptions of plastic surgeons as craniofacial surgery specialists in Brazil. Methods: Brazilian residents were asked to choose 1 or 2 specialists that they perceived to be an expert for 14 craniofacial surgery-related scenarios. Both an overall analysis (all 14 scenarios) and subanalysis (each scenario separately) were performed. Response patterns were distributed as “plastic surgeons alone,” “plastic surgeons combined with other specialists,” or “without plastic surgeons... περισσότερα »
The Application of Surgical Navigation in the Treatment of Temporomandibular Joint Ankylosis
Alexandros G. SfakianakisστοΚοσμητική ΟδοντοΙατρική και ΓναθοΧειρουργικήΠριν από 1 ώρα
The Application of Surgical Navigation in the Treatment of Temporomandibular Joint Ankylosis: [image: image] Objective: The purpose of this study was to assess the safety and the accuracy of surgical navigation technology in the resection of severe ankylosis of the mandibular condyle with the middle cranial fossa. Methods: The computed tomography scan data were transferred to a Windows-based computer workstation, and the patient's individual anatomy was assessed in multiplanar views at the workstation. In the operation, the patient and the virtual image were matched by individual re...περισσότερα »
Classification of Computer-Aided Design–Computer-Aided Manufacturing Applications for the Reconstruction of Cranio-Maxillo-Facial Defects
Alexandros G. SfakianakisστοΚοσμητική ΟδοντοΙατρική και ΓναθοΧειρουργικήΠριν από 1 ώρα
Classification of Computer-Aided Design–Computer-Aided Manufacturing Applications for the Reconstruction of Cranio-Maxillo-Facial Defects: [image: image]Purpose: To gain insight into the methodology of different computer-aided design–computer-aided manufacturing (CAD-CAM) applications for the reconstruction of cranio-maxillo-facial (CMF) defects. Methods: We reviewed and analyzed the available literature pertaining to CAD-CAM for use in CMF reconstruction. Results: We proposed a classification system of the techniques of implant and cutting, drilling, and/or guiding template design an...περισσότερα »
Orbital Wall Restoring Surgery for Inferomedial Blowout Fracture
Alexandros G. SfakianakisστοΚοσμητική ΟδοντοΙατρική και ΓναθοΧειρουργικήΠριν από 1 ώρα
Orbital Wall Restoring Surgery for Inferomedial Blowout Fracture: [image: image]Abstract: Repairing a large inferomedial blowout fracture remains a challenge to orbital surgeon. The authors restored the fracture using combined transnasal and transorbital approaches using support of both paranasal sinuses. The authors compared surgical results of this novel method with those of the traditional procedure. Of 106 inferomedial blowout fracture patients who underwent surgical treatment between March 2007 and July 2013, 50 patients were selected in our study: 25 patients underwent the tra...περισσότερα »
Fast and Early Mandibular Osteodistraction: The Long-Term Follow-Up of Mandibular Distraction Osteogenesis on Teeth Position
Alexandros G. SfakianakisστοΚοσμητική ΟδοντοΙατρική και ΓναθοΧειρουργικήΠριν από 1 ώρα
Fast and Early Mandibular Osteodistraction: The Long-Term Follow-Up of Mandibular Distraction Osteogenesis on Teeth Position: [image: image]Abstract: Pierre Robin Sequence is a congenital pathology defined by the triad micrognathia, glossoptosis and often a U-shaped cleft of soft palate. Newborns affected by airways obstruction may necessitate more invasive options: tongue-lip adhesion, tracheostomy and mandibular distraction osteogenesis. The authors analyzed the effect of fast and early mandibular osteodistraction on deciduous dental development in patients affected by Pierre Robi...περισσότερα »
Complete Mulberry Hypertrophy and Conchachoanal Polyp of Inferior Turbinate
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 1 ώρα
Complete Mulberry Hypertrophy and Conchachoanal Polyp of Inferior Turbinate: [image: image]
Evaluation of Relationship Between Body Dysmorphic Disorder and Self-Esteem in Rhinoplasty Candidates
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 1 ώρα
Evaluation of Relationship Between Body Dysmorphic Disorder and Self-Esteem in Rhinoplasty Candidates: [image: image]Aim: To investigate the relationship between body dysmorphic syndrome and self-esteem in rhinoplasty candidates. Results: A negative statistical correlation was evident between Rosenberg Self-Esteem Scale (RSES) and Body Dysmorphic Disorder Examination-Self Report (BDDE-SR) scores. In terms of responses to the first Body Dysmorphic Disorder Questionnaire (BDDQ) question, which focuses on general attitude toward body dysmorphic syndrome, the average RSES “YES” score was... περισσότερα »
Total Airway Reconstruction in the Neonate: Combined Mandibular Distraction and Slide Tracheoplasty for Multiple Level Airway Obstruction
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 1 ώρα
Total Airway Reconstruction in the Neonate: Combined Mandibular Distraction and Slide Tracheoplasty for Multiple Level Airway Obstruction: [image: image] Background: Long-segment congenital tracheal stenosis (CTS) is characterized by segmental tracheal stenosis, complete tracheal rings, and absent posterior pars membranosa for >50% of tracheal length. Slide tracheoplasty on cardiopulmonary bypass (CPB) has traditionally been the procedure of choice for airway reconstruction. Pierre Robin sequence (PRS) is characterized by the triad of micrognathia, glossoptosis, and airway obstruct... περισσότερα »
Monitoring Enoxaparin with Antifactor Xa Levels in Obese Patients
Alexandros G. SfakianakisστοΝοσολογίαΠριν από 1 ώρα
Study Objectives To characterize antifactor Xa peak levels (as therapeutic, subtherapeutic, and supratherapeutic) in morbidly obese patients receiving treatment doses of enoxaparin, using a therapeutic range of 0.5–1.1 units/ml, and to assess the occurrence of bleeding complications in these patients. Design Retrospective cohort study. Setting Community hospital. Patients Ninety-nine morbidly obese patients (body mass index [BMI] higher than 40 kg/m2 or total body weight more than 150 kg) who received at least three doses of the standard treatment dosage of enoxaparin and had ...περισσότερα »
Implications of Augmented Renal Clearance on Drug Dosing in Critically Ill Patients: A Focus on Antibiotics
Alexandros G. SfakianakisστοΝοσολογίαΠριν από 1 ώρα
Augmented renal clearance (ARC) has been reported in approximately 30–65% of patients in the intensive care unit (ICU) despite the presence of a normal serum creatinine concentration. In certain ICU patient populations (e.g., patients with sepsis or trauma), the incidence increases to roughly 50–85%. Risk factors for ARC include the following: age younger than 50–55 years, male sex, higher diastolic blood pressure, fewer comorbidities, and a lower Acute Physiology and Chronic Health Evaluation II (APACHE II) or modified Sequential Organ Failure Assessment (SOFA) score at ICU admi...περισσότερα »
Salvaging the Exposed Cochlear Implant
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 1 ώρα
Salvaging the Exposed Cochlear Implant: [image: image] Abstract: Cochlear implant exposure is an uncommon occurrence that may imperil the fate of the implant. Insertion of this costly device is a delicate procedure, and reimplantation with another implant after removal is expensive and emotionally stressful for patients. Salvage of the original implant can be quite successful with a fully vascularized scalp-nape of the neck rotation flap. The authors review the literature and report their experience in salvaging exposed implants in 2 patients, who had risk factors that compromised ... περισσότερα »
Arteriovenous Hemangioma of the Ear Lobule
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 1 ώρα
Arteriovenous Hemangioma of the Ear Lobule: [image: image]Abstract: Primary tumors arising from the ear lobule are uncommon, and hemangiomas in this region are extremely rare. The authors report a case of an arteriovenous hemangioma in the left ear lobule. The mass was reddish-colored, soft, mobile, nonpulsatile, and not tender on palpation. There was no recurrence 22 months after surgical excision.
Is Three-Dimensional Soft Tissue Prediction by Software Accurate?
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 1 ώρα
Is Three-Dimensional Soft Tissue Prediction by Software Accurate?: Abstract: The authors assessed whether virtual surgery, performed with a soft tissue prediction program, could correctly simulate the actual surgical outcome, focusing on soft tissue movement. Preoperative and postoperative computed tomography (CT) data for 29 patients, who had undergone orthognathic surgery, were obtained and analyzed using the Simplant Pro software. The program made a predicted soft tissue image (A) based on presurgical CT data. After the operation, we obtained actual postoperative CT data and an ...περισσότερα »
Bilateral Continuous Automated Distraction Osteogenesis: Proof of Principle
Alexandros G. SfakianakisστοΚοσμητική ΟδοντοΙατρική και ΓναθοΧειρουργικήΠριν από 1 ώρα
Bilateral Continuous Automated Distraction Osteogenesis: Proof of Principle: [image: image] Abstract: The purpose of this study was to demonstrate that automated, continuous, curvilinear distraction osteogenesis (DO) in a minipig model is effective when performed bilaterally, at rates up to 3 mm/day, to achieve clinically relevant lengthening. A Yucatan minipig in the mixed dentition phase underwent bilaterally, at a continuous DO at a rate of 2 mm/day at the center of rotation; 1.0 and 3.0 mm/day at the superior and inferior regions, respectively. The distraction period was 13 day... περισσότερα »
Health-Related Quality of Life Patients With a Cleft Lip and/or Palate
Alexandros G. SfakianakisστοΚοσμητική ΟδοντοΙατρική και ΓναθοΧειρουργικήΠριν από 1 ώρα
Health-Related Quality of Life Patients With a Cleft Lip and/or Palate: Background: The authors evaluated health-related quality of life (HRQoL) in patients with cleft lip and/or palate (CLP). Methods: A descriptive, observational, cross-sectional study was conducted in the largest referral facility for treating individuals with CLP in Sergipe state. The authors created 3 groups with 97 subjects each: CLP, family, and control. An initial cognitive evaluation was performed with the Mini-Mental State Examination, and the Medical Outcomes Study 36 item Short-Form Health Survey (SF-36) w... περισσότερα »
Up-and-Coming Mandibular Reconstruction Technique With Autologous Human Bone Marrow Stem Cells and Iliac Bone Graft in Patients With Large Bony Defect
Alexandros G. SfakianakisστοΚοσμητική ΟδοντοΙατρική και ΓναθοΧειρουργικήΠριν από 1 ώρα
Up-and-Coming Mandibular Reconstruction Technique With Autologous Human Bone Marrow Stem Cells and Iliac Bone Graft in Patients With Large Bony Defect: [image: image]Abstract: Large bony defects followed by resection of the mandible need to be reconstructed by various surgical techniques such as the fibular flap. In this article, we report the case of mandibular reconstruction with autologous human bone marrow mesenchymal stem cells and autogenous bone graft, followed by placement of dental implants and prosthodontic treatment in a patient who has been failed to reconstruct mandibul... περισσότερα »
A Multidisciplinary Evaluation of Prescribing Practices for Prophylactic Antibiotics in Operative and Nonoperative Facial Fractures
Alexandros G. SfakianakisστοΚοσμητική ΟδοντοΙατρική και ΓναθοΧειρουργικήΠριν από 1 ώρα
A Multidisciplinary Evaluation of Prescribing Practices for Prophylactic Antibiotics in Operative and Nonoperative Facial Fractures: [image: image]Background: Evidence supports short-term perioperative prophylaxis for facial fractures. It is unknown, however, whether there is any professional consensus on how to manage these injuries. No multidisciplinary evaluation of the prophylactic antibiotic prescribing patterns for neither operative nor nonoperative facial fractures has been performed. Aim: To evaluate the prophylactic antibiotic prescribing patterns of multiple specialties in ... περισσότερα »
Juxta-articular Myxoma of the Temporomandibular Joint
Alexandros G. SfakianakisστοΚοσμητική ΟδοντοΙατρική και ΓναθοΧειρουργικήΠριν από 1 ώρα
Juxta-articular Myxoma of the Temporomandibular Joint: [image: image]Abstract: The juxta-articular myxoma represents a benign mesenchymal neoplasm that arises from tissue within or adjacent to a joint space. There have been a number of reported cases involving myxomas of the knee, shoulder, elbow, wrist, and hip. To our knowledge there, however, have been no reported cases of juxta-articular myxomas of the temporomandibular joint (TMJ). This report describes the case of a 57-year-old woman with a juxta-articular myxoma of the left TMJ extending into the infratemporal fossa (ITF). Acc...περισσότερα »
The Psychologic and Psychosocial Impact of Otoplasty on Children and Adults
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 1 ώρα
The Psychologic and Psychosocial Impact of Otoplasty on Children and Adults: Background: In previous studies, our research group already evaluated the impact of aesthetic surgery on “quality of life” (QoL). This study evaluates QoL factors and perceptions of well-being after otoplasty as a single indication. Methods: Eighty-one patients who underwent otoplasty were divided into three age groups: Youth 1 (Y1) = 8–12 years (n = 17), Youth 1 (Y2) = 13–17 years (n = 13), and Adult ≥18 years (n = 51). For competitive analysis, 2 groups of tests were used: a standardized self-assessment te... περισσότερα »
Midline Cleft Lip and Bifid Nose Deformity: Description, Classification, and Treatment
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 1 ώρα
Midline Cleft Lip and Bifid Nose Deformity: Description, Classification, and Treatment: [image: image]Background: Midline facial clefts are rare and challenging deformities caused by failure of fusion of the medial nasal prominences. These anomalies vary in severity, and may include microform lines or midline lip notching, incomplete or complete labial clefting, nasal bifidity, or severe craniofacial bony and soft tissue anomalies with orbital hypertelorism and frontoethmoidal encephaloceles. In this study, the authors present 4 cases, classify the spectrum of midline cleft anomalie... περισσότερα »
Albumin Levels in Patients With Chronic Rhinosinusitis With Nasal Polyp
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 1 ώρα
Albumin Levels in Patients With Chronic Rhinosinusitis With Nasal Polyp Abstract Objectives: We aim to provide useful evidence on the relationship between the albumin levels and chronic rhinosinusitis with nasal polyp (CRSwNP) and its potential use as an inexpensive, reliable, and independent prognostic marker of CRSwNP. Materials and Methods: Forty-five patients with CRSwNP and 45 healthy individuals were included in the study. Serum albumin levels were determined. The serum albumin levels of the study and control groups were compared to determine whether there is a statistically...περισσότερα »
Temporal Bone Localized Chondroblastoma
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 1 ώρα
Temporal Bone Localized Chondroblastoma: [image: image]Abstract: Chondroblastoma is a highly destructive tumor originating from immature cartilage cells. Although chondroblastoma is defined as a benign tumor, it may exhibit malign tumor behaviors such as invasion or metastasis on neighboring structures. Magnetic resonance (MR) image is a solid mass lesion, which included heterogeneous hypointense in T2A and heterogeneous minimal hyperintense in T1A with destructive expansile characteristics and millimetric calcifications. Temporal bone chondroblastomas may complicate the diagnosis b...περισσότερα »
Assessing Patient-Reported Outcomes Following Orthognathic Surgery and Osseous Genioplasty
Alexandros G. SfakianakisστοΚοσμητική ΟδοντοΙατρική και ΓναθοΧειρουργικήΠριν από 1 ώρα
Assessing Patient-Reported Outcomes Following Orthognathic Surgery and Osseous Genioplasty: Abstract: Primary outcomes for orthognathic surgery and genioplasty patients include satisfaction with appearance, improved motor function, and enhanced quality of life. The goal of this study was to assess outcomes among patients undergoing these procedures, and to highlight the potential use of FACE-Q instrument for use in patients with dentofacial deformities. A total of 56 patients presenting for orthognathic surgery and/or osseous genioplasty completed the FACE-Q during preoperative and...περισσότερα »
Reconstruction of Rare Skull Metastases Using Free Latissimus Dorsi Flap and the Role of Preoperative Embolization in Hypervascular Skull Tumors
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 1 ώρα
Reconstruction of Rare Skull Metastases Using Free Latissimus Dorsi Flap and the Role of Preoperative Embolization in Hypervascular Skull Tumors: [image: image]Abstract: Metastatic tumors are the most common cranial neoplasms in adults. Skull metastases from rare primary tumors, such as cholangiocarcinoma or pancreatic neuroendocrine tumor, are extremely uncommon and rarely reported. Given the scarcity and variation of these rare skull metastases, treatments and outcomes of such patients are of interest to treating surgeons. The authors describe the treatment algorithm, course, and o...περισσότερα »
Characteristics of Maxillofacial Trauma Among Alcohol and Drug Users
Alexandros G. SfakianakisστοΚοσμητική ΟδοντοΙατρική και ΓναθοΧειρουργικήΠριν από 1 ώρα
Characteristics of Maxillofacial Trauma Among Alcohol and Drug Users: Abstract: The aim of the current study was to identify and compare the characteristics of maxillofacial trauma in alcohol and drug users with those of nonusers. A retrospective study was conducted using the medical records of patients treated for facial trauma between April 1999 and March 2012 at the Maxillofacial Surgery Division of the Piracicaba Dental School. The data were analyzed by descriptive analysis, binary logistic regression, and correlational analysis using SPSS 18.0 software. The results were conside...περισσότερα »
Reverse Distraction Cranioplasty for Treatment of Hydrocephalic Megalocephaly
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 1 ώρα
Reverse Distraction Cranioplasty for Treatment of Hydrocephalic Megalocephaly: Abstract: Macrocephaly resulting from untreated hydrocephalus is a rare but difficult condition to treat. The patient presented is a 6-year-old boy who had progressively increasing head size since birth secondary to untreated hydrocephalus with associated developmental delay. His initial head circumference was 69 cm, and computed tomography scan showed evidence of obstructive hydrocephalus. For the first stage of the procedure, bicoronal and circumferential strip craniectomies were performed, 5 fully open...περισσότερα »
Triple V-Y Vermilion Augmentation of the Upper Lip
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 1 ώρα
Triple V-Y Vermilion Augmentation of the Upper Lip: [image: image]Abstract: Lip enhancement is one of the most common procedures in the facial cosmetic surgery. The most important reason for that is the fact that fullness of lips symbolizes youth and sensuality. The authors present 2 patients whose upper lip vermilion dimension was increased using the triple V-Y augmentation surgical technique. The main request for both was augmentation of the upper lip without dermal fillers and implants into the lip. Treatment and postrecovery were routine. After 1 month both upper lips had satisfa... περισσότερα »
A Novel Method to Attain Highly Symmetric Oblique Mandibular Chin-Body Osteotomy
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 1 ώρα
A Novel Method to Attain Highly Symmetric Oblique Mandibular Chin-Body Osteotomy: [image: image] Oblique mandibular chin-body osteotomy is a widely used narrowing genioplasty. However, the historic challenge is how to achieve a highly symmetric result of oblique mandibular chin-body osteotomy. Here, we present a novel and simple method to achieve a highly symmetrical mandibular chin-body osteotomy.
Aggravated Medial Orbital Wall Fracture After Reduction of Orbital Floor Fracture
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 1 ώρα
A Case of Aggravated Medial Orbital Wall Fracture After Reduction of Orbital Floor Fracture: [image: image]Abstract: Concomitant fractures of the inferior and medial orbital wall can cause more severe orbital symptoms and lead to incomplete reduction postoperatively. This report presents the case of a 17-year-old boy, presenting with persistent diplopia and enophthalmos after floor reduction for concomitant fractures. At the time of the fracture, surgery was performed for only the orbital floor by a plastic surgeon, because the medial wall fracture was minimal. However, he presented... περισσότερα »
Prevalence and Consequences of Positional Plagiocephaly and Brachycephaly
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 1 ώρα
Prevalence and Consequences of Positional Plagiocephaly and Brachycephaly: Abstract: The incidence of positional plagiocephaly and brachycephaly in infants has increased. Treatment options include physiotherapy and helmet therapy. No information exists on the prevalence, cosmetic, and psychological consequences of plagiocephaly and brachycephaly later in life. This study was performed to assess the prevalence and cosmetic relevance of plagiocephaly and brachycephaly, as well as its influence on quality of life in adolescence. The authors performed plagiocephalomety to assess cranial ...περισσότερα »
Is the Maxillary Sinus Really Suitable in Sex Determination? A Three-Dimensional Analysis of Maxillary Sinus Volume and Surface Depending on Sex and Dentition
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 1 ώρα
Is the Maxillary Sinus Really Suitable in Sex Determination? A Three-Dimensional Analysis of Maxillary Sinus Volume and Surface Depending on Sex and Dentition: [image: image] Abstract: The morphometric analysis of maxillary sinus was recently presented as a helpful instrument for sex determination. The aim of the present study was to examine the volume and surface of the fully dentate, partial, and complete edentulous maxillary sinus depending on the sex. Computed tomography data from 276 patients were imported in DICOM format via special virtual planning software, and surfaces (mm...περισσότερα »
Evaluation of the Trephine Method in Harvesting Bone Graft From the Anterior Iliac Crest for Oral and Maxillofacial Reconstructive Surgery
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 1 ώρα
Evaluation of the Trephine Method in Harvesting Bone Graft From the Anterior Iliac Crest for Oral and Maxillofacial Reconstructive Surgery: Abstract: Autogenous bone graft is the gold standard for maxillofacial reconstruction. Although there are many donor sites, the ilium is favored. Open iliac bone harvesting techniques can result in significant complications, which are to be reduced; a minimally invasive technique using trephine burs was used. The aim of the study was to evaluate the intra- and postoperative complications, the size of bone harvested, and the time of the procedure...περισσότερα »
Nasopharyngeal Mass Diagnosed as Transsphenoidal Encephalocele in an Adult Patient
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 1 ώρα
Nasopharyngeal Mass Diagnosed as Transsphenoidal Encephalocele in an Adult Patient: [image: image]Abstract: Transsphenoidal encephalocele, a rare congenital malformation, is generally diagnosed during childhood when investigating the reason for complaints such as nasal obstruction and recurring cerebrospinal fluid fistula. In this adult patient, the authors identified an asymptomatic transsphenoidal encephalocele after requested monitoring of a pedunculated mass detected in the nasopharynx during nasal endoscopy. After evaluation, the authors decided to follow the patient. Few cases...περισσότερα »
The Reconstruction of Nasal Septum Perforations: Alar Winged Flap
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 1 ώρα
A Different Approach to the Reconstruction of Nasal Septum Perforations: Alar Winged Flap: Purpose: Nasal septal perforations (NSPs) are one of the major complications among the nose surgery that the surgeon has to solve it. There are many reasons on the etiology of septal perforation such as iatrogenic and idiopathic. All the surgical procedures are based on 2 main principles, namely repair using an intranasal flaps: mucosal, mucoperichondrial, mucoperiosteal flaps within the nasal cavity; and extranasal flaps. Operation can be carried out using either the “closed technique” or “op... περισσότερα »
Antibiotic Use in Pregnancy
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 1 ώρα
A Review of Antibiotic Use in Pregnancy: During pregnancy, untreated sexually transmitted or urinary tract infections are associated with significant morbidity, including low birth weight, preterm birth, and spontaneous abortion. Approximately one in four women will be prescribed an antibiotic during pregnancy, accounting for nearly 80% of prescription medications in pregnant women. Antibiotic exposures during pregnancy have been associated with both short-term (e.g., congenital abnormalities) and long-term effects (e.g., changes in gut microbiome, asthma, atopic dermatitis) in the... περισσότερα »
Influenza Antiviral Expenditures and Outpatient Prescriptions
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 1 ώρα
Influenza Antiviral Expenditures and Outpatient Prescriptions in the United States, 2003–2012: Study Objectives The clinical efficacy and cost-effectiveness of influenza antiviral use are controversial, with recent analyses suggesting potentially limited value. Thus, the objectives of this study were to describe influenza antiviral expenditures overall and by health care setting over a 10-year period (2003–2012) and to assess the correlation between outpatient influenza antiviral prescription use and influenza-like illness (ILI) outpatient visits. Design Retrospective, cross-sectio... περισσότερα »
Risk multipliers for severe food anaphylaxis
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 1 ώρα
Risk multipliers for severe food anaphylaxis: Anaphylaxis is a severe, life threatening allergic reaction. In most fatal cases of food anaphylaxis, the fatality is not due merely to a simple, linear relationship between the allergen and exposure in a sensitized individual. Compounding factors such as the allergic disease burden—particularly the presence of asthma; comprehension of the potential severity of an event, training in the appropriate use of epinephrine, and emerging metabolic factors should be considered when assessing risk and establishing management strategies. This pape... περισσότερα »
Outcomes of mucosal melanoma of the head and neck
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 1 ώρα
Outcomes of mucosal melanoma of the head and neck: Abstract Introduction Mucosal melanoma of the head and neck is a rare disease with limited data available on outcomes; therefore, we reviewed our institutional experience. Methods An institutional database was queried and 38 patients with head and neck mucosal melanoma were identified. Charts were abstracted and local control (LC), progression-free survival (PFS) and overall survival (OS) were calculated. Results Most patients had T4 disease (86%), although nodes were positive in 11%. En bloc or endoscopic resection was performed on ...περισσότερα »
Dead Nano-Sized Lactobacillus plantarum Inhibits Azoxymethane/Dextran Sulfate Sodium-Induced Colon Cancer in Balb/c Mice
Αλέξανδρος ΣφακιανάκηςστοMedicine by Alexandros G.SfakianakisΠριν από 1 ώρα
Journal of Medicinal Food , Vol. 0, No. 0. from #Medicine via ola Kala on Inoreader http://ift.tt/1SYxxnV via IFTTT
The Female Sexual Function Index (FSFI): Translation, Validation, and Cross-Cultural Adaptation of an Urdu Version “FSFI–U”
Αλέξανδρος ΣφακιανάκηςστοMedicine by Alexandros G.SfakianakisΠριν από 1 ώρα
Abstract Introduction Female sexual dysfunction (FSD) is a common problem, and many self-report questionnaires are available for its evaluation. Pakistani women with sexual problems feel shy to consult with their physician. A validated self-report questionnaire, in the local language with modest expressions is required for these women. Aim The aim of this study was to translate, cross-culturally adapt, and perform a psychometric validation of an Urdu translation of the Female Sexual Function Index (FSFI). Methods The FSFI was translated in Urdu, and its precision was ascertaine... περισσότερα »
Corrigendum to “Inhibition of human topoisomerase I and II and anti-proliferative effects on MCF-7 cells by new titanocene complexes” [Bioorg. Med. Chem. 23 (2015) 7302–7312]
Αλέξανδρος ΣφακιανάκηςστοMedicine by Alexandros G.SfakianakisΠριν από 1 ώρα
Publication date: Available online 23 November 2015 *Source:*Bioorganic & Medicinal Chemistry Author(s): Adele Chimento, Carmela Saturnino, Domenico Iacopetta, Rosaria Mazzotta, Anna Caruso, Maria Rosaria Plutino, Annaluisa Mariconda, Anna Ramunno, Maria Stefania Sinicropi, Vincenzo Pezzi, Pasquale Longo from #Medicine via ola Kala on Inoreader http://ift.tt/1XnpLoJ via IFTTT
Reducing emergency CT radiation doses with simple techniques
Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 1 ώρα
Reducing emergency CT radiation doses with simple techniques: A quality initiative project: Abstract Introduction Use of indication-specific CT protocols and adjustment of scan parameters to decrease radiation exposure may result in significant dose reduction. We implemented these strategies and compare pre- and post-implementation radiation dose in emergency department (ED) patients. Method This was a descriptive, retrospective study. Patients older than 15 years who had undergone emergency CT examinations of the head, chest, abdomen, pelvis and abdominopelvic region in periods bef...περισσότερα »
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