Eugenol, α-pinene and β-caryophyllene from Plectranthus barbatus essential oil as eco-friendly larvicides against malaria, dengue and Japanese encephalitis mosquito vectors
Eugenol, α-pinene and β-caryophyllene from Plectranthus barbatus essential oil as eco-friendly larvicides against malaria, dengue and Japanese encephalitis mosquito vectors: AbstractMosquito-borne diseases represent a deadly threat for millions of people worldwide. Eco-friendly mosquitocides are a priority. In Ayurvedic medicine, *Plectranthus* species have been used to treat heart disease, convulsions, spasmodic pain and painful urination. In this research, we evaluated the acute toxicity of essential oil from *Plectranthus barbatus* and its major constituents, against larvae of t... περισσότερα »
Dengue virus’ evaluation with flow virometry
Dengue virus’ evaluation with flow virometry: Read the full article on ScienceDirect*Flow virometry used to address the maturation stage of individual virions **Text by Sonia Zicari* Dengue virus (DENV) is a small positive single-stranded RNA enveloped Flavivirus that is formed as a non-infectious particle, which undergoes maturation by cleavage of a protein (prM) on its surface. Different prMs are cleaved at different time-points/locations, resulting in viral heterogeneity both at the population and at the individual particle levels. Bulk analyses cannot capture this heterogeneity... περισσότερα »
Epidemiology and molecular mechanisms of antifungal resistance in Candida and Aspergillus
Epidemiology and molecular mechanisms of antifungal resistance in Candida and Aspergillus: Summary The significant increase in the use of antifungal agents, both for the treatment of candidiasis and invasive aspergillosis and as azole fungicides in agricultural crop protection has resulted in the emergence of resistant clinical isolates, particularly to triazoles and echinocandins. Notably, among isolates that were primarily sensitive to fluconazole such as *Candida parapsilosis* and *Candida tropicalis* have witnessed an emerging resistance development. Also for echinocandins, the... περισσότερα »
Repeatability and sensitivity of T2* measurements in patients with head and neck squamous cell carcinoma at 3T
Repeatability and sensitivity of T2* measurements in patients with head and neck squamous cell carcinoma at 3T: Purpose To determine whether quantitation of [image: inline image] is sufficiently repeatable and sensitive to detect clinically relevant oxygenation levels in head and neck squamous cell carcinoma (HNSCC) at 3T. Materials and Methods Ten patients with newly diagnosed locally advanced HNSCC underwent two magnetic resonance imaging (MRI) scans between 24 and 168 hours apart prior to chemoradiotherapy treatment. A multiple gradient echo sequence was used to calculate [ima... περισσότερα »
Flow diverter treatment of posterior circulation aneurysms
Flow diverter treatment of posterior circulation aneurysms. A meta-analysis: Abstract IntroductionTreatment of complex anterior circulation aneurysms with flow diverters (FDs) has become common practice in neurovascular centers. However, this treatment method for posterior circulation aneurysms (PCAs) still remains controversial. MethodsThrough searches for reports on the treatment of PCAs with FDs, we conducted a systematic review of the literature on its clinical efficacy and safety using random-effect binomial meta-analysis. ResultsWe included 14 studies, which reported ... περισσότερα »
A mass lesion misdiagnosed as a malignant tumor in the masticator space: a case report
A mass lesion misdiagnosed as a malignant tumor in the masticator space: a case report: AbstractTemporomandibular disorder (TMD) is common, affecting up to 28 % of the population. Inflammatory conditions, developmental abnormalities, and neoplasms involving the masticator space can result in symptomatic TMD, which may present with signs such as pain and trismus. Because TMD treatments, including surgical management, differ according to the underlying cause, imaging plays an important role in identifying the precise category of TMD. Here, we report a case of an inflammatory lesion ...περισσότερα »
Phase 2 clinical trial of sunitinib as adjunctive treatment in patients with advanced differentiated thyroid cancer
Phase 2 clinical trial of sunitinib as adjunctive treatment in patients with advanced differentiated thyroid cancer: Objective Our objective was to evaluate the efficacy and safety of sunitinib following at least one course of radioactive iodine treatment in patients with advanced differentiated thyroid cancer (DTC). The study endpoints included best response rate (including best objective response rate) and progression-free survival (PFS) per Response Evaluation Criteria in Solid Tumors (RECIST) 1.1, measurement of serum thyroglobulin (Tg), and toxicity evaluation. Design and meth... περισσότερα »
Prevalence and characteristics of spontaneous tinnitus in 11-year-old children
10.3109/14992027.2015.1120890<br>Rachel Humphriss from #Audiology via ola Kala on Inoreader http://ift.tt/1OVkJfo via IFTTT
Emerging technologies with potential for objectively evaluating speech recognition skills
10.3109/14992027.2015.1128570<br>Vishakha Waman Rawool from #Audiology via ola Kala on Inoreader http://ift.tt/1OVkLni via IFTTT
Emerging technologies with potential for objectively evaluating speech recognition skills.
*Emerging technologies with potential for objectively evaluating speech recognition skills.* Int J Audiol. 2016 Jan 25;:1-10 Authors: Rawool VW Abstract Work-related exposure to noise and other ototoxins can cause damage to the cochlea, synapses between the inner hair cells, a auditory nerve fibers, and higher auditory pathways, leading to difficulties in recognizing speech. Procedures designed to determine speech recognition scores (SRS) in an objective manner can be helpful in disability compensation cases where the worker claims to have poor speech perception due to exposure ...περισσότερα »
Prevalence and characteristics of spontaneous tinnitus in 11-year-old children.
*Prevalence and characteristics of spontaneous tinnitus in 11-year-old children.* Int J Audiol. 2016 Jan 25;:1-7 Authors: Humphriss R, Hall AJ, Baguley DM Abstract OBJECTIVE: To estimate the prevalence of spontaneous tinnitus in 11-year-old children. DESIGN: A prospective UK population-based study. STUDY SAMPLE: A total of 7092 children from the Avon longitudinal study of parents and children (ALSPAC) who attended the hearing session at age 11 years and answered questions about tinnitus. RESULTS: We estimated the prevalence of any spontaneous tinnitus as 28.1% (95% CI 27.1, 29.2%... περισσότερα »
COMPARISION OF bNOS AND CHAT IMMUNOHISTOCHEMISTRY IN THE LATERODORSAL TEGMENTUM (LDT) AND THE PEDUNCULOPONTINE TEGMENTUM (PPT) OF THE MOUSE FROM BRAIN SLICES PREPARED FOR ELECTROPHYSIOLOGY
[image: S01650270.gif] Publication date: Available online 25 January 2016 *Source:*Journal of Neuroscience Methods Author(s): Maxime Veleanu, Tina E. Axen, Morten P. Kristensen, Kristi A. Kohlmeier BackgroundIdentification of cell phenotype from brain slices upon which in vitro electrophysiological recordings have been performed often relies on conducting post hoc immunohistochemistry on tissue that necessarily has not been ideally prepared for immunohistochemical procedures. In such studies, antibody labeling against neuronal nitric oxide synthase (bNOS) has been used to identify c... περισσότερα »
Vasopressin and sympathetic system mediate the cardiovascular effects of the angiotensin II in the bed nucleus of the stria terminalis in rat
[image: S01680102.gif] Publication date: Available online 25 January 2016 *Source:*Neuroscience Research Author(s): Ali Nasimi, Marzieh Kafami The bed nucleus of the stria terminalis (BST) is involved in behavioral, neuroendocrine and autonomic functions, including cardiovascular regulation. The angiotensin II (Ang II) receptor (AT1), and angiotensinogen were found in the BST. In our previous study we found that microinjection of Ang II into the BST produced a pressor response with no consistent effect on heart rate. This study was performed to find the possible peripheral mechanism...περισσότερα »
Pituitary autoimmunity.Idiopathic GH deficiency (GHD)
Longitudinal behavior of autoimmune GH deficiency: from childhood to transition age: Background Some cases of apparently idiopathic GH deficiency (GHD) may be caused by pituitary autoimmunity. Objective To study the variations in pituitary function and antipituitary antibodies (APA) from childhood to transition age in patients with apparently idiopathic GHD. Design We conducted a longitudinal study. Patients and methods Pituitary function and APA detection by immunofluorescence were investigated in 24 childhood patients with isolated GHD before starting recombinant GH therapy a... περισσότερα »
Sporadic GH-secreting pituitary adenomas
Landscape of somatic mutations in sporadic GH-secreting pituitary adenomas: Context Alterations in the cAMP signaling pathway are common in hormonally active endocrine tumors. Somatic mutations at *GNAS* are causative in 30–40% of GH-secreting adenomas. Recently, mutations affecting the *USP8* and *PRKACA* gene have been reported in ACTH-secreting pituitary adenomas and cortisol-secreting adrenocortical adenomas respectively. However, the pathogenesis of many GH-secreting adenomas remains unclear. Aim Comprehensive genetic characterization of sporadic GH-secreting adenomas and ide... περισσότερα »
A higher wrist circumference was associated with lower risk for incident CVD
Wrist circumference as a novel negative risk factor for cardiovascular disease among adult men: a median follow-up of 9 years: Abstract PurposeWrist circumference is an easy to measure anthropometric index of body frame and bone size. The aim of this study was to examine the association of wrist circumference with incidence of cardiovascular disease (CVD) among adult men. MethodsFor this study 2531 male participants aged ≥30 years, without any history of CVD were selected and followed from 1999 to 2011. Cox proportional hazard models and logistic regression were used to examine...περισσότερα »
Vitamin D status in children and adolescents with autoimmune thyroiditis
Vitamin D status in children and adolescents with autoimmune thyroiditis: Abstract BackgroundVitamin D deficiency is a global health problem. Its role as an immune modulator has been recently emphasized. There is increasing evidence for the significant role of vitamin D in reducing the incidence of autoimmune diseases. However, little is known about the status of vitamin D in children and adolescents with autoimmune thyroiditis (AIT). ObjectiveThe goal of the present study was to assess vitamin D status in Egyptian children and adolescents with AIT and to explore its relation to... περισσότερα »
Importance of concomitant topical therapy in moderate-to-severe atopic dermatitis treated with cyclosporine
Importance of concomitant topical therapy in moderate-to-severe atopic dermatitis treated with cyclosporine: ABSTRACT Cyclosporine (CS) is widely used in patients with refractory atopic dermatitis (AD). During CS treatment, many patients have a tendency to decrease their adherence to topical agents as their disease improves. Our aim was to compare the efficacy and relapse rate of CS treatment combined with topical therapy and CS monotherapy. This prospective, randomized, 6 month study involved 60 patients with moderate-to-severe AD who were randomly assigned to two groups, one rece...περισσότερα »
A causal relationship between hearing loss and cognitive impairment.
*A causal relationship between hearing loss and cognitive impairment.* Acta Otolaryngol. 2016 Jan 25;:1-4 Authors: Park SY, Kim MJ, Sikandaner H, Kim DK, Yeo SW, Park SN Abstract Conclusion Moderate hearing loss in young mice caused decreases in cognition associated with spatial working and recognition memories in 6 months. These results provide evidence for a causal relationship between hearing loss and cognitive impairment. Objectives Hypothesized mechanisms to connect sensory and cognitive functions include the sensory-deprivation, information-degradation, and common-cause hyp...περισσότερα »
Correlation of climbing perception and eye movements during daytime and nighttime takeoffs using a flight simulator.
*Correlation of climbing perception and eye movements during daytime and nighttime takeoffs using a flight simulator.* Acta Otolaryngol. 2016 Jan 25;:1-6 Authors: Tamura A, Wada Y, Shimizu N, Inui T, Shiotani A Abstract Conclusion This study suggests that the subjective climbing perception can be quantitatively evaluated using values calculated from induced eye movements, and the findings may aid in the detection of pilots who are susceptible to spatial disorientation in a screening test. Objective The climbing perception experienced by a pilot during takeoff at night is stronge... περισσότερα »
Isolated Vestibular Suppression Impairment With Vestibular Migraine: A Phenotypic CANVAS Variant.
*Isolated Vestibular Suppression Impairment With Vestibular Migraine: A Phenotypic CANVAS Variant.* Otol Neurotol. 2016 Jan 20; Authors: Migliaccio AA, Watson SR Abstract HYPOTHESIS: Cerebellar Ataxia with Neuropathy and Vestibular Areflexia (CANVAS) is likely to have a genetic basis. We describe the unique eye movement features of a possible phenotypic CANVAS variant. BACKGROUND: The patient comes from a large CANVAS kindred (four out of nine siblings) and has sensory neuropathy, cerebellar eye signs, and vestibular migraine (VM), but otherwise normal vestibular function. METHOD... περισσότερα »
Sanna Classification and Prognosis of Cholesteatoma of the Petrous Part of the Temporal Bone: A Retrospective Series of 81 Patients.
*Sanna Classification and Prognosis of Cholesteatoma of the Petrous Part of the Temporal Bone: A Retrospective Series of 81 Patients.* Otol Neurotol. 2016 Jan 20; Authors: Danesi G, Cooper T, Panciera DT, Manni V, Côté DW Abstract OBJECTIVE: To determine how classification of petrous bone cholesteatomas (PBCs) using the 5-point Sanna classification can predict major structural involvement, facial nerve outcomes, hearing outcomes, postoperative complications, and disease recurrence. STUDY DESIGN: Retrospective case series. SETTING: Tertiary referral center in Bergamo, Italy. PATIEN... περισσότερα »
Sensorineural Hearing Loss in Cholesteatoma.
*Sensorineural Hearing Loss in Cholesteatoma.* Otol Neurotol. 2016 Jan 20; Authors: Rosito LS, Netto LS, Teixeira AR, da Costa SS Abstract OBJECTIVE: To determine whether middle ear cholesteatoma is associated with, sensorineural hearing loss, and whether patient age, cholesteatoma growth pattern, or, air bone gap size contribute to inner ear impairment. STUDY DESIGN: Cross-sectional comparative. SETTING: A tertiary hospital. PATIENTS: The subjects were 115 patients with middle ear cholesteatoma in one ear, and normal video-otoscopy in the contralateral ear (CLE). INTERVENTIONS: Ot...περισσότερα »
Lower facial reanimation techniques following cancer resection and free flap reconstruction.
*Lower facial reanimation techniques following cancer resection and free flap reconstruction.* Laryngoscope. 2016 Jan 25; Authors: Kejner AE, Rosenthal EL Abstract OBJECTIVES/HYPOTHESIS: Evaluate outcomes of the standard static sling and orthodromic temporalis tendon transfer reanimation for facial nerve paralysis. STUDY DESIGN: Retrospective case series at a tertiary care hospital of head and neck cancer patients with facial nerve palsy secondary to malignancy or resection. METHODS: From 2004 to 2014, patients undergoing resection of malignancy that involved facial nerve palsy ...περισσότερα »
Intranasal topical estrogen in the management of epistaxis in hereditary hemorrhagic telangiectasia.
*Intranasal topical estrogen in the management of epistaxis in hereditary hemorrhagic telangiectasia.* Acta Otolaryngol. 2016 Jan 25;:1-4 Authors: Minami K, Haji T Abstract Conclusion Application of topical estriol ointment is an effective treatment for hereditary hemorrhagic telangiectasia (HHT) epistaxis. Objective HHT is an autosomal-dominant disease characterized by epistaxis in more than 96% of patients. Management of this major symptom, epistaxis, has not been standardized. This study reports experience with topical application of estriol in patients with HHT. Methods Five...περισσότερα »
Meta-Analyses of Microarray Datasets Identifies ANO1 and FADD as Prognostic Markers of Head and Neck Cancer.
*Meta-Analyses of Microarray Datasets Identifies ANO1 and FADD as Prognostic Markers of Head and Neck Cancer.* PLoS One. 2016;11(1):e0147409 Authors: Reddy RB, Bhat AR, James BL, Govindan SV, Mathew R, Dr R, Hedne N, Illiayaraja J, Kekatpure V, Khora SS, Hicks W, Tata P, Kuriakose MA, Suresh A Abstract The head and neck squamous cell carcinoma (HNSCC) transcriptome has been profiled extensively, nevertheless, identifying biomarkers that are clinically relevant and thereby with translational benefit, has been a major challenge. The objective of this study was to use a meta-analys... περισσότερα »
Validation of a French-Language Version of the Spatial Hearing Questionnaire, Cluster Analysis and Comparison with the Speech, Spatial, and Qualities of Hearing Scale.
*Validation of a French-Language Version of the Spatial Hearing Questionnaire, Cluster Analysis and Comparison with the Speech, Spatial, and Qualities of Hearing Scale.* Ear Hear. 2016 Jan 20; Authors: Moulin A, Richard C Abstract OBJECTIVES: To validate a French-language version of the spatial hearing questionnaire (SHQ), including investigating its internal structure using cluster analysis and exploring its construct validity on a large population of hearing-impaired (HI) and normal-hearing (NH) subjects, and to compare the SHQ with the speech, spatial, and qualities of hearin... περισσότερα »
HPV prevalence in HIV patients with head and neck squamous cell carcinoma.
*HPV prevalence in HIV patients with head and neck squamous cell carcinoma.* AIDS. 2016 Jan 23; Authors: Picard A, Badoual C, Hourseau M, Halimi C, Pere H, Dib F, Barry B, Albert S Abstract OBJECTIVE: The implication of HPV in head and neck squamous cell carcinoma (HNSCC) is well established, especially in oropharyngeal SCC. HIV patients have a higher risk of persistent HPV infection. We investigated the role of HPV in HNSCC carcinogenesis in HIV population. DESIGN: Retrospective monocentric study. METHODS: We studied HIV patients who presented with HNSCC between 1994 and 2014. F... περισσότερα »
Interaction between osseous and non-osseous vibratory stimulation of the human cadaveric head.
*Interaction between osseous and non-osseous vibratory stimulation of the human cadaveric head.* Hear Res. 2016 Jan 22; Authors: Sim JH, Dobrev I, Gerig R, Pfiffner F, Stenfelt S, Huber AM, Röösli C Abstract Bone conduction (BC) stimulation can be applied by vibration to the bony or skin covered skull (osseous BC), or on soft tissue such as the neck (non-osseous BC). The interaction between osseous and non-osseous bone conduction pathways is assessed in this study. The relation between bone vibrations measured at the cochlear promontory and the intracranial sound pressure for s... περισσότερα »
Influence of geometry and materials on the axial and torsional strength of the head-neck taper junction in modular hip replacements: A finite element study.
*Influence of geometry and materials on the axial and torsional strength of the head-neck taper junction in modular hip replacements: A finite element study.* J Mech Behav Biomed Mater. 2016 Jan 7;60:118-126 Authors: Fallahnezhad K, Farhoudi H, Oskouei RH, Taylor M Abstract The assembly force is important in establishing the mechanical environment at the head-neck taper junction of modular hip replacements. Previous experimental results of the assembled taper junctions with different material combinations (Co-28Cr-6Mo and Ti-6Al-4V) reported similar axial strengths (pull-off loa... περισσότερα »
Dupilumab: a revolutionary emerging drug in atopic dermatitis and its possible role in pemphigus
Dupilumab: a revolutionary emerging drug in atopic dermatitis and its possible role in pemphigus Dupilumab From Wikipedia, the free encyclopedia DupilumabMonoclonal antibodyTypeWhole antibodySourceHumanTargetIL4 receptor alphaIdentifiersCAS Number1190264-60-8ATC codeNoneChemical dataFormulaC6512H 10066N1730O2052S46Molecular mass146.9 kDa *Dupilumab* is a monoclonal antibody designed for the treatment of atopic diseases.[1] It binds to the alpha subunit of the interleukin-4 receptor (IL-4Rα).[2] Through blockade of IL-4Rα, dupilumab modulates signaling of both theinterleukin 4 and in... περισσότερα »
Daylight methyl-aminolevulinate photodynamic therapy versus ingenol mebutate for the treatment of actinic keratoses: an intraindividual comparative analysis
Daylight methyl-aminolevulinate photodynamic therapy versus ingenol mebutate for the treatment of actinic keratoses: an intraindividual comparative analysis: ABSTRACT Daylight-photodynamic therapy (D-PDT) and ingenol mebutate (IM) are novel therapies directed to actinic keratoses (AK). The purpose of our study was to compare effectiveness, tolerability, cosmetic outcome and patient preference of D-PDT versus IM in the treatment of grade I and II AK. Twenty-seven patients with AK on the face or scalp were enrolled. Each patient received, in a 25 cm2 target area, D-PDT on right side ...περισσότερα »
Hyper-IgE Syndrome in an Infant
Hyper-IgE Syndrome in an Infant: Background: Hyper–immunoglobulin E syndrome (HIES) is a rare primary immunodeficiency disorder that affects multiple systems. One of the early findings is a papulopustular rash, which has a wide differential diagnosis. Method: The authors report the case of a male newborn diagnosed with HIES. He presented with papulopustular dermatitis on the scalp. The authors also present a review of current theory on the pathophysiology, clinical presentation, and management of HIES. Conclusion: Although HIES is a multisystem disorder, many of the manifestations... περισσότερα »
Carbon Dioxide Laser Ablation of Basal Cell Carcinoma with Visual Guidance by Reflectance Confocal Microscopy: A Proof of Principle Pilot Study
Carbon Dioxide Laser Ablation of Basal Cell Carcinoma with Visual Guidance by Reflectance Confocal Microscopy: A Proof of Principle Pilot Study: Abstract Background Laser ablation is an alternative, non-surgical treatment modality for low-risk basal cell carcinoma (BCC); however, lack of confirmative tumour destruction or residual tumour presence has been a limiting factor to adoption. Reflectance confocal microscopy (RCM) provides non-invasive, cellular-level resolution imaging of the skin and is capable of identifying tumour. Objective To evaluate the use of RCM to guide carbon di... περισσότερα »
Regorafenib induced hand-foot skin reaction with striking epidermal dysmaturation - a new histopathological pattern associated with the use of multi-kinase inhibitors
Regorafenib induced hand-foot skin reaction with striking epidermal dysmaturation - a new histopathological pattern associated with the use of multi-kinase inhibitors: Abstract Chemotherapy-associated epidermal dysmaturation promotes the appearance of a pattern of epidermal changes and inflammation. This is a complication typical of treatments with pegylated liposomal doxorubicin or taxanes. Multi-kinase inhibitor drugs, e.g. regorafenib, interact with oncogenic pathways involved in the emergence of different types of tumors. Hand foot skin reaction (HFSR) is a common side effect o...περισσότερα »
BCG vaccine for immunotherapy in warts
BCG vaccine for immunotherapy in warts: is it really safe in a tuberculosis endemic area?: ABSTRACT Management of recurrent and or recalcitrant warts can be a therapeutic challenge and in such cases invoking body's own immunity may help to overcome the present episode and also prevent recurrences. Bacilli Calmette Geurin (BCG) immunotherapy has long been considered to be an effective and safe modality in such cases. We present a series of seven cases treated with BCG immunotherapy wherein a single dose of BCG caused regression of wart in 85.7% patients and complete resolution was e...περισσότερα »
Hypertrophic lichen planus treatment with acitretin
Hypertrophic lichen planus – successful treatment with acitretin: ABSTRACT Lichen planus classifies into different subtypes according to morphology and location. Hypertrophic LP (HLP) manifests a great challenge due to persistent itching, the risk to develop into squamous cell carcinoma and therapeutic resistance. We report two clinical cases exemplary for the successful treatment of dramatic-resistant HLP with acitretin. Acitretin From Wikipedia, the free encyclopedia Acitretin[image: Acitretin2DACS.svg]Systematic (IUPAC) name (2*E*,4*E*,6*E*,8*E*)-9-(4-methoxy-2,3,6-trimethylph... περισσότερα »
Hypertrophic lichen planus – successful treatment with acitretin
Hypertrophic lichen planus – successful treatment with acitretin: ABSTRACT Lichen planus classifies into different subtypes according to morphology and location. Hypertrophic LP (HLP) manifests a great challenge due to persistent itching, the risk to develop into squamous cell carcinoma and therapeutic resistance. We report two clinical cases exemplary for the successful treatment of dramatic-resistant HLP with acitretin.
Needle-free injection of 5-aminolevulinic acid in photodynamic therapy for the treatment of non-melanoma skin cancer
Needle-free injection of 5-aminolevulinic acid in photodynamic therapy for the treatment of non-melanoma skin cancer: ABSTRACT Background Photodynamic therapy (PDT) has been widely used in treatment for skin cancer. However, topical 5-aminolevulinic acid (ALA) in PDT demonstrates poor therapeutic effect due to its shallow penetration. And intralesional ALA-PDT can bring great pain. The purpose of this study was to evaluate the efficacy of PDT with needle-free injection of ALA in the treatment of nonmalignant skin tumors. Methods 54 non-melanocytic malignant lesions of 54 subjects we...περισσότερα »
Translational research on influenza virus infection using a nonhuman primate model
Translational research on influenza virus infection using a nonhuman primate model: Influenza virus infection is a seasonal infectious disease for humans, whereas it is also a zoonosis that is originally transmitted from animals to humans. Therefore, several animal models are used in research on influenza virus infection. We have used a nonhuman primate (NHP) model to extrapolate pathogenicity of various influenza viruses and efficacy of vaccines and antiviral drugs against the influenza viruses in humans. NHPs have genes, anatomical structure, and immune responses similar to those...περισσότερα »
Laryngeal Mask Ventilation During Lumbar Spine Neurosurgery
Laryngeal Mask Ventilation During Lumbar Spine Neurosurgery in Knee-Chest Position is Feasible.: Background: This study describes our experience with laryngeal mask (LM) inserted after anesthetic induction in patients already in knee-chest position for lumbar neurosurgery. Methods: Airway management (need for LM repositioning, orotracheal intubation because of failed LM insertion), anticipated difficult airway, and airway complications were registered. Statistics were compared between groups with the t test or the [chi]2 test, as appropriate. Results: A total of 358 cases were reviewe... περισσότερα »
Postoperative Pain Management in Children
Postoperative Pain Management in Children of Hispanic Origin: A Descriptive Cohort Study: [image: image] BACKGROUND: It has been established that pain is frequently undertreated in children following outpatient surgery. Very few studies, however, have investigated this phenomenon in ethnically diverse populations. METHODS: This study included 105 families of children aged 2 to 15 years of Hispanic origin and low income undergoing outpatient tonsillectomy and adenoidectomy surgery. Participating parents completed baseline and demographic packets. Recorded postoperative pain ratings a...περισσότερα »
Siblings Promote a Type 1/Type 17-oriented immune response in the airways of asymptomatic neonates
Siblings Promote a Type 1/Type 17-oriented immune response in the airways of asymptomatic neonates: [image: cover.gif?v=1&s=e49413b3a608982cc9a6b00f] Abstract Background Siblings have been shown to reduce the risk of later asthma and allergy, but the mechanism driving this association is unknown. The objective was to study whether siblings affect the airway immune response in healthy neonates. We hypothesized that siblings exert immune modulatory effects on neonates mirrored in the airway mucosa. Methods We measured 20 immune-mediators related to the Type 1, Type 2, Type 17 or r...περισσότερα »
Membranes, Vol. 6, Pages 11: Ling’s Adsorption Theory as a Mechanism of Membrane Potential Generation Observed in Both Living and Nonliving Systems
The potential between two electrolytic solutions separated by a membrane impermeable to ions was measured and the generation mechanism of potential measured was investigated. From the physiological point of view, a nonzero membrane potential or action potential cannot be observed across the impermeable membrane. However, a nonzero membrane potential including action potential-like potential was clearly observed. Those observations gave rise to a doubt concerning the validity of currently accepted generation mechanism of membrane potential and action potential of cell. As an altern...περισσότερα »
Materials, Vol. 9, Pages 74: Properties of Non-Structural Concrete Made with Mixed Recycled Aggregates and Low Cement Content
In spite of not being legally accepted in most countries, mixed recycled aggregates (MRA) could be a suitable raw material for concrete manufacturing. The aims of this research were as follows: (i) to analyze the effect of the replacement ratio of natural coarse aggregates with MRA, the amount of ceramic particles in MRA, and the amount of cement, on the mechanical and physical properties of a non-structural concrete made with a low cement content; and (ii) to verify if it is possible to achieve a low-strength concrete that replaces a greater amount of natural aggregate with MRA a... περισσότερα »
Identification of infants and preschool children at risk for asthma
Identification of infants and preschool children at risk for asthma: predictive scores and biomarkers.: Purpose of review: Predictive asthma scores and biomarkers are important tools that help many physicians in the identification of infants and preschool children at high risk for asthma. Our objective was to review recent data regarding this subject. Recent findings: Recently, two new predictive asthma scores were developed with some innovative features, such as the definition of scales of asthma risk. In a systematic review, 12 asthma-predictive models were identified with heteroge... περισσότερα »
The Pittsburgh Sleep Quality Index among pregnant women
Construct validity and factor structure of the Pittsburgh Sleep Quality Index among pregnant women in a Pacific-Northwest cohort: Abstract PurposePoor sleep quality during pregnancy is associated with adverse obstetric and neuropsychiatric outcomes. Despite its routine use as a sleep quality assessment scale among men and non-pregnant women, the psychometric properties of the Pittsburgh Sleep Quality Index (PSQI) have not been assessed among US pregnant women. We sought to evaluate the construct validity and factor structure of the PSQI among 1488 pregnant women. MethodsA struc... περισσότερα »
Racial disparity in adherence to positive airway pressure
Racial disparity in adherence to positive airway pressure among US veterans: Abstract PurposeDespite advances in continuous positive airway pressure (CPAP) technology, compliance with CPAP therapy remains suboptimal. Studies conducted since the advent of objective CPAP recording have noted that African Americans (AA) may use CPAP less than Whites. We sought to confirm this finding among a large sample of veterans and examine effect modifiers of the differential usage. MethodsA retrospective cohort of 233 AA and 1939 White Veterans Administration (VA) patients who had a sleep s... περισσότερα »
Association between continuous positive airway pressure and circulating omentin levels in patients with obstructive sleep apnoea
Association between continuous positive airway pressure and circulating omentin levels in patients with obstructive sleep apnoea: Abstract PurposeInflammation and oxidative stress play important roles in the pathogenesis of obstructive sleep apnoea syndrome (OSAS). Omentin is expressed in visceral adipose tissue and is associated with the inflammatory response. The aim of this study was to assess the relationship between OSAS and omentin based on a comparison of its serum levels at baseline and after 3 months of continuous positive airway pressure (CPAP) therapy. MethodsNinety...περισσότερα »
An oral appliance with or without elastic bands to control mouth opening during sleep—a randomized pilot study
An oral appliance with or without elastic bands to control mouth opening during sleep—a randomized pilot study: Abstract BackgroundOral appliances (OAs) hold the lower jaw forward to reduce obstructive sleep apneas. Some OA designs allow mouth opening, which influences the forward positioning of the lower jaw. The aim of this pilot study was to compare the efficacy of an adjustable, custom-made OA (Narval®) in its original design, which allowed mouth opening, with the same OA with elastic bands that restricted mouth opening. MethodsConsecutive patients with an apnea-hypopnea in... περισσότερα »
Three-dimensional assessment of anatomical balance and oral appliance treatment outcome in obstructive sleep apnoea
Three-dimensional assessment of anatomical balance and oral appliance treatment outcome in obstructive sleep apnoea: Abstract PurposeMandibular advancement splints (MAS) are an effective treatment for obstructive sleep apnoea (OSA). However, MAS are not equally efficacious across all patients and the reasons are not well understood. Craniofacial and upper airway structure individually influence MAS response. We aimed to assess anatomical balance, defined as the ratio of upper airway soft tissue (ST) volume to maxillomandibular enclosure volume, between MAS treatment responders and...περισσότερα »
Conductive gelatin methacrylate-polyaniline hydrogels
Fabrication of via Acta Biomaterialia Publication date: Available online 25 January 2016 *Source:*Acta Biomaterialia Author(s): Yibo Wu, Yong X. Chen, Jiahan Yan, David Quinn, Ping Dong, Stephen W. Sawyer, Pranav Soman Hydrogels with inherently conductive properties have been recently developed for tissue engineering applications, to serve as bioactive scaffolds to electrically stimulate cells and modulate their function. In this work, we have used interfacial polymerization of aniline monomers within gelatin methacrylate (GelMA) to develop a conductive hybrid composite. We demonstra... περισσότερα »
High-density antimicrobial peptide coating with broad activity and low cytotoxicity against human cells
High-density antimicrobial peptide coating with broad activity and low cytotoxicity against human cells via Acta Biomaterialia Publication date: Available online 25 January 2016 *Source:*Acta Biomaterialia Author(s): Akhilesh Rai, Sandra Pinto, Marta B. Evangelista, Helena Gil, Silvar Kallip, Mario G.S. Ferreira, Lino Ferreira Medical device-associated infections are a multi-billion dollar burden for the worldwide healthcare systems. The modification of medical devices with non-leaching coatings capable of killing microorganisms on contact is one of the strategies being investigated to... περισσότερα »
Patterned, tubular scaffolds mimic longitudinal and radial mechanics of the neonatal trachea
Patterned, tubular scaffolds mimic longitudinal and radial mechanics of the neonatal trachea via Acta Biomaterialia Publication date: Available online 25 January 2016 *Source:*Acta Biomaterialia Author(s): Elizabeth G. Mansfield, Vaughn K. Greene, Debra T. Auguste Tracheal damage, abnormality or absence can result from the growth of tumors or from Congenital High Airway Obstruction Syndrome. No optimal or routine treatment has been established for tracheal repair, despite numerous attempts with natural and artificial prostheses. The fetal trachea is comprised of cartilaginous rings con... περισσότερα »
Diabetes and Periodontitis
Diabetes and Periodontitis—A Dental Hygienist’s Perspective: AbstractSeveral decades of research of the interrelationships between diabetes and periodontitis have evolved into a significant body of knowledge that should be incorporated into dental practice. However, there may be a delay in implementing this important information into everyday patient care. Oral healthcare providers (i.e., dentists and dental hygienists) should be progressively engaged in changing the trajectory of the epidemics of diabetes and periodontitis. This article synthesizes the cumulative evidence on the d... περισσότερα »
Visual Cross-Modal Re-Organization in Children with Cochlear Implants
Visual Cross-Modal Re-Organization in Children with Cochlear Implants: by Julia Campbell, Anu Sharma Background Visual cross-modal re-organization is a neurophysiological process that occurs in deafness. The intact sensory modality of vision recruits cortical areas from the deprived sensory modality of audition. Such compensatory plasticity is documented in deaf adults and animals, and is related to deficits in speech perception performance in cochlear-implanted adults. However, it is unclear whether visual cross-modal re-organization takes place in cochlear-implanted children an... περισσότερα »
Vestibular Migraine: Vestibular Symptom May Identify Different Subgroups.
Vestibular Migraine: Vestibular Symptom May Identify Different Subgroups.: Objective: The objective of this study was to evaluate patients with vestibular migraine and analyze whether different vestibular symptoms were able to discriminate different subgroups. Patients: Eighty-three patients (73 women, mean age 42 yr) who fulfilled the criteria for vestibular migraine were selected. Intervention: Participants were divided into two groups according to their vestibular symptoms: spontaneous vertigo (SV) or triggered vertigo (TV). In each group, migraine subtype (migraine with aura and m...περισσότερα »
The Meniett device can reduce the dizziness and vertigo symptoms of Ménière's disease
About Meniett Therapy The Meniett device can reduce the dizziness and vertigo symptoms of Ménière's disease so you can get back to enjoying life.1-12 Most doctors prescribe 3 Meniett treatments a day, 5 minutes each time. The Meniett device is small and portable, so you can use it just about anywhere. What Is Micropressure Therapy? Micropressure therapy for Ménière's disease developed from research on pressure changes and the inner ear, beginning in the 1960s.13-16 The American Academy of Otolaryngology supports using micropressure therapy for certain cases of Ménière’s disease, espec... περισσότερα »
Meniett Therapy for Meniere's Disease
Meniett Therapy for Meniere's Disease: An Updated Meta-analysis.: Objective: To re-evaluate the efficacy of Meniett therapy for the treatment of Meniere's disease (MD). Data Sources: PubMed, Embase, Cochrane Library, Clinicaltrials.gov, ChiCTR, and the CNKI database were searched for articles in English and Chinese published before August 31, 2015. Study Selection: Included in this meta-analysis were studies that dealt with outcomes of Meniett therapy for the treatment of MD, including randomized controlled clinical trials, case-control studies, and prospective or retrospective cohor... περισσότερα »
The Use of Temporoparietal Fascial Flap to Eliminate Wound Breakdown in Subtotal Petrosectomy for Chronic Discharging Ears.
The Use of Temporoparietal Fascial Flap to Eliminate Wound Breakdown in Subtotal Petrosectomy for Chronic Discharging Ears.: Objective: To find out if the use of the vascularized temporo-parietal fascial flap (TPFF) reduces postoperative infection or wound breakdown in subtotal petrosectomy for chronic discharging ears. Patients: A retrospective review on 26 subtotal petrosectomies with blind pit closures on chronic discharging ears performed by a single surgeon between 2000 and 2015 was performed. All patients had a minimum follow-up period of 6 months. Intervention: Eleven mastoid ... περισσότερα »
Isolated Vestibular Suppression Impairment With Vestibular Migraine: A Phenotypic CANVAS Variant.
Isolated Vestibular Suppression Impairment With Vestibular Migraine: A Phenotypic CANVAS Variant.: Hypothesis: Cerebellar Ataxia with Neuropathy and Vestibular Areflexia (CANVAS) is likely to have a genetic basis. We describe the unique eye movement features of a possible phenotypic CANVAS variant. Background: The patient comes from a large CANVAS kindred (four out of nine siblings) and has sensory neuropathy, cerebellar eye signs, and vestibular migraine (VM), but otherwise normal vestibular function. Methods: We recorded eye and head movements using the gold standard scleral search... περισσότερα »
Sanna Classification and Prognosis of Cholesteatoma of the Petrous Part of the Temporal Bone: A Retrospective Series of 81 Patients.
Sanna Classification and Prognosis of Cholesteatoma of the Petrous Part of the Temporal Bone: A Retrospective Series of 81 Patients.: Objective: To determine how classification of petrous bone cholesteatomas (PBCs) using the 5-point Sanna classification can predict major structural involvement, facial nerve outcomes, hearing outcomes, postoperative complications, and disease recurrence. Study Design: Retrospective case series. Setting: Tertiary referral center in Bergamo, Italy. Patients: Eighty-one sequential patients with radiologic and surgically confirmed diagnoses of PBC treated ... περισσότερα »
Sensorineural Hearing Loss in Cholesteatoma.
Sensorineural Hearing Loss in Cholesteatoma.: Objective: To determine whether middle ear cholesteatoma is associated with, sensorineural hearing loss, and whether patient age, cholesteatoma growth pattern, or, air bone gap size contribute to inner ear impairment. Study Design: Cross-sectional comparative. Setting: A tertiary hospital. Patients: The subjects were 115 patients with middle ear cholesteatoma in one ear, and normal video-otoscopy in the contralateral ear (CLE). Interventions: Otoendoscopy, pure-tone audiometry. Main Outcome Measures: Bone conduction (BC) threshold difference...περισσότερα »
Validation of a French-Language Version of the Spatial Hearing Questionnaire, Cluster Analysis and Comparison with the Speech, Spatial, and Qualities of Hearing Scale.
Validation of a French-Language Version of the Spatial Hearing Questionnaire, Cluster Analysis and Comparison with the Speech, Spatial, and Qualities of Hearing Scale.: Objectives: To validate a French-language version of the spatial hearing questionnaire (SHQ), including investigating its internal structure using cluster analysis and exploring its construct validity on a large population of hearing-impaired (HI) and normal-hearing (NH) subjects, and to compare the SHQ with the speech, spatial, and qualities of hearing scale (SSQ) in the same population. Design: The SHQ was translate... περισσότερα »
Esophageal Carcinoma with an Aberrant Right Subclavian Artery
[A Case of Esophageal Carcinoma with an Aberrant Right Subclavian Artery].: *[A Case of Esophageal Carcinoma with an Aberrant Right Subclavian Artery].* Gan To Kagaku Ryoho. Authors: Tokunou K, Yamamoto T, Kamei R, Kitamura Y, Ando S Abstract We report a rare case of esophagealcarcinoma with an aberrant right subclavian artery. A 67-year-old woman was admitted to our hospital because of a sense of discomfort during swallowing. A detailed gastrointestinal examination revealed advanced carcinoma of the middle thoracic esophagus. Preoperative CT also revealed an aberrant right subcla...περισσότερα »
HPV prevalence in HIV patients with head and neck squamous cell carcinoma.
HPV prevalence in HIV patients with head and neck squamous cell carcinoma.: *HPV prevalence in HIV patients with head and neck squamous cell carcinoma.* AIDS. 2016 Jan 23; Authors: Picard A, Badoual C, Hourseau M, Halimi C, Pere H, Dib F, Barry B, Albert S Abstract OBJECTIVE: The implication of HPV in head and neck squamous cell carcinoma (HNSCC) is well established, especially in oropharyngeal SCC. HIV patients have a higher risk of persistent HPV infection. We investigated the role of HPV in HNSCC carcinogenesis in HIV population. DESIGN: Retrospective monocentric study. METHO... περισσότερα »
Overweight and obesity predict better overall survival rates in cancer patients with distant metastases
Overweight and obesity predict better overall survival rates in cancer patients with distant metastases: Abstract Recent studies conducted in patients with chronic diseases have reported an inverse association between body mass index (BMI) and mortality. However, the question as to whether BMI may predict prognosis in patients with metastatic cancer remains open. We therefore designed the current retrospective study to investigate the potential association between BMI and overall survival (OS) in patients with distant metastases (DM) and a favorable performance status. Between 2000... περισσότερα »
Prognostic impact and potential interaction of EGFR and c-Met in the progression of esophageal squamous cell carcinoma
Prognostic impact and potential interaction of EGFR and c-Met in the progression of esophageal squamous cell carcinoma: AbstractThis study is to examine EGFR and c-Met variation in precancerous lesion, early esophageal squamous cell carcinoma (ESCC), and advanced ESCC and to explore their prognostic significance. EGFR and c-Met were detected by immunohistochemistry (IHC) and fluorescence in situ hybridization (FISH). Of 158 endoscopy resection (ER) specimens, c-Met high expression and FISH positive were 44.9 and 12.6 %, respectively. EGFR high expression and FISH positive were 2.5 ... περισσότερα »
Immediate and Delayed Hypersensitivity Reactions to Proton Pump Inhibitors: Evaluation and Management
Immediate and Delayed Hypersensitivity Reactions to Proton Pump Inhibitors: Evaluation and Management: AbstractPPIs are among the most commonly administered medications in the USA and are generally well tolerated. Immediate and delayed immune-mediated hypersensitivity reactions are rare but increasingly recognized adverse effects of proton pump inhibitors (PPIs). Immediate hypersensitivity reactions can occur due to IgE-mediated hypersensitivity to PPIs and can be evaluated by immediate hypersensitivity skin testing and oral provocation challenge testing. A desensitization protocol...περισσότερα »
Spontaneous cerebrospinal fluid leaks in the anterior skull base
Spontaneous cerebrospinal fluid leaks in the anterior skull base: a surgical challenge.: Related Articles*Spontaneous cerebrospinal fluid leaks in the anterior skull base: a surgical challenge.* J Laryngol Otol. Authors: Martínez-Capoccioni G, Serramito-García R, Huertas-Pardo B, García-Allut A, Martín-Martín C Abstract OBJECTIVE: This retrospective study aimed to evaluate the effective closure rate for spontaneous cerebrospinal fluid leaks with functional endoscopic sinus surgery and identify patient characteristics that may be associated with a need for additional therapy. ME... περισσότερα »
Audit of transoral laser-assisted microsurgical resection of early laryngeal cancer.
Audit of transoral laser-assisted microsurgical resection of early laryngeal cancer Authors: Amir I, Vernham GA Abstract OBJECTIVE: This study aimed to report our current practice of transoral laser microsurgery for early glottic cancer against the standards outlined by the ENT UK Head and Neck Group and assess the oncological outcome. METHOD: A retrospective review of case notes of patients diagnosed with early glottic cancer (tumour stages Tis, T1 and T2) who underwent transoral laser microsurgery as a primary curative treatment. The minimum follow-up period was two years. RESU... περισσότερα »
[The options of surgery and laryngeal preservation for hypopharyngeal cancer patients more than 65 years old].
[The options of surgery and laryngeal preservation for hypopharyngeal cancer patients more than 65 years old] Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. Authors: Wang Q, Liu Y, Hu G, Wu K, Gao C, Zhao Y Abstract OBJECTIVE: To study the effectiveness of preserving laryngeal function for senile hypopharyngeal cancer patientsolder than 65. METHOD: The clinical data of 58 surgery cases of senile hypopharyngeal cancer patients more than 65 years old were colleted and analyzed. Thirty-one cases preserved the laryngeal function, while the rest did not. Perfect preoperative preparati...περισσότερα »
Multifunctional and Context-Dependent Control of Vocal Acoustics by Individual Muscles.
Multifunctional and Context-Dependent Control of Vocal Acoustics by Individual Muscles.: [image: http:--highwire.stanford.edu-icons-exter] Authors: Srivastava KH, Elemans CP, Sober SJ Abstract The relationship between muscle activity and behavioral output determines how the brain controls and modifies complex skills. In vocal control, ensembles of muscles are used to precisely tune single acoustic parameters such as fundamental frequency and sound amplitude. If individual vocal muscles were dedicated to the control of single parameters, then the brain could control each parameter... περισσότερα »
Emerging technologies with potential for objectively evaluating speech recognition skills.
*Emerging technologies with potential for objectively evaluating speech recognition skills.* Int J Audiol. 2016 Jan 25;:1-10 Authors: Rawool VW Abstract Work-related exposure to noise and other ototoxins can cause damage to the cochlea, synapses between the inner hair cells, a auditory nerve fibers, and higher auditory pathways, leading to difficulties in recognizing speech. Procedures designed to determine speech recognition scores (SRS) in an objective manner can be helpful in disability compensation cases where the worker claims to have poor speech perception due to exposure ...περισσότερα »
Prevalence and characteristics of spontaneous tinnitus in 11-year-old children.
*Prevalence and characteristics of spontaneous tinnitus in 11-year-old children.* Int J Audiol. 2016 Jan 25;:1-7 Authors: Humphriss R, Hall AJ, Baguley DM Abstract OBJECTIVE: To estimate the prevalence of spontaneous tinnitus in 11-year-old children. DESIGN: A prospective UK population-based study. STUDY SAMPLE: A total of 7092 children from the Avon longitudinal study of parents and children (ALSPAC) who attended the hearing session at age 11 years and answered questions about tinnitus. RESULTS: We estimated the prevalence of any spontaneous tinnitus as 28.1% (95% CI 27.1, 29.2%... περισσότερα »
Poststroke Rehabilitation and Restorative Care Utilization: A Comparison Between VA Community Living Centers and VA-contracted Community Nursing Homes.
*Poststroke Rehabilitation and Restorative Care Utilization: A Comparison Between VA Community Living Centers and VA-contracted Community Nursing Homes.* Med Care. 2016 Jan 22; Authors: Jia H, Pei Q, Sullivan CT, Cowper Ripley DC, Wu SS, Bates BE, Vogel WB, Bidelspach DE, Wang X, Hoffman N Abstract BACKGROUND: Effective poststroke rehabilitation care can speed patient recovery and minimize patient functional disabilities. Veterans affairs (VA) community living centers (CLCs) and VA-contracted community nursing homes (CNHs) are the 2 major sources of institutional long-term care ...περισσότερα »
Depressive Symptoms Before, During, and After Delirium: A Literature Review.
*Depressive Symptoms Before, During, and After Delirium: A Literature Review.* Psychosomatics. 2015 Nov 10; Authors: Nelson S, Rustad JK, Catalano G, Stern TA, Kozel FA Abstract BACKGROUND: Delirium and depression are often thought of as mutually exclusive conditions. However, several studies cite depression as a risk factor for delirium whereas others note that patients with delirium often manifest depressive symptoms. Whether these depressive symptoms persist after delirium resolves remains unclear. OBJECTIVES: This article reviews published studies that have investigated the ...περισσότερα »
Fixed multibracket dental therapy has challenges but can be successfully performed in young persons with Down syndrome.
*Fixed multibracket dental therapy has challenges but can be successfully performed in young persons with Down syndrome.* Disabil Rehabil. 2016 Jan 23;:1-6 Authors: Abeleira MT, Pazos E, Limeres J, Outumuro M, Diniz M, Diz P Abstract Purpose The objective of this study was to analyze the feasibility of orthodontic treatment with fixed multibracket dental appliances (FMAs) in patients with Down syndrome (DS). Methods The study sample was formed of 25 patients with DS who underwent orthodontic treatment with FMAs. Dental and skeletal characteristics, aspects of FMA treatment, retai...περισσότερα »
The relationship between perceived injustice and the working alliance: a cross-sectional study of patients with persistent pain attending multidisciplinary rehabilitation.
*The relationship between perceived injustice and the working alliance: a cross-sectional study of patients with persistent pain attending multidisciplinary rehabilitation.* Disabil Rehabil. 2016 Jan 23;:1-9 Authors: Scott W, Milioto M, Trost Z, Sullivan MJ Abstract Purpose Accumulating research suggests that perceived injustice is a risk factor for adverse recovery following painful injury. Presently, however, little is known about the processes by which perceived injustice influences rehabilitation outcomes. It is plausible that perceived injustice and associated anger impact ... περισσότερα »
Improving a web-based employability intervention for work-disabled employees: results of a pilot economic evaluation.
*Improving a web-based employability intervention for work-disabled employees: results of a pilot economic evaluation.* Disabil Rehabil Assist Technol. 2016 Jan 23;:1-10 Authors: Noben C, Evers S, Genabeek JV, Nijhuis F, de Rijk A Abstract Purpose The purpose of this study is to improve web-based employability interventions for employees with work-related health problems for both intervention content and study design by means of a pilot economic evaluation. Methods Uptake rate analysis for the intervention elements, cost effectiveness, cost utility and subgroup analyses were cond... περισσότερα »
The role of TWEAK/Fn14 signaling in the MPTP-model of Parkinson's disease.
*The role of TWEAK/Fn14 signaling in the MPTP-model of Parkinson's disease.* Neuroscience. 2016 Jan 22; Authors: Mustafa S, Martin HL, Burkly L, Costa A, Martins ML, Schwaninger M, Teismann P Abstract The tumor necrosis factor like weak inducer of apoptosis (TWEAK) and its receptor, fibroblast growth factor-inducible 14 (Fn14), mediate inflammation and neuronal apoptosis in cerebral edema, ischemic stroke and multiple sclerosis. The downstream effectors and pathways linked to TWEAK-Fn14 signaling are strongly implicated in the pathology of Parkinson's disease (PD), thus indicati...περισσότερα »
Erratum: Development, appraisal, validation and implementation of a consensus protocol for the assessment of cerebral amyloid angiopathy in post-mortem brain tissue.
*Erratum: Development, appraisal, validation and implementation of a consensus protocol for the assessment of cerebral amyloid angiopathy in post-mortem brain tissue.* Am J Neurodegener Dis. 2015;4(2):49 Authors: Love S, Chalmers K, Ince P, Esiri M, Attems J, Kalaria R, Jellinger K, Yamada M, McCarron M, Minett T, Matthews F, Greenberg S, Mann D, Kehoe PG Abstract In a collaboration involving 11 groups with research interests in cerebral amyloid angiopathy (CAA), we used a two-stage process to develop and in turn validate a new consensus protocol and scoring scheme for the asse...περισσότερα »
Mitochondrial DNA differentiates Alzheimer from Creutzfeldt-Jakob disease.
*Mitochondrial DNA differentiates Alzheimer from Creutzfeldt-Jakob disease.* Alzheimers Dement. 2016 Jan 21; Authors: Podlesniy P, Llorens F, Golanska E, Sikorska B, Liberski P, Zerr I, Trullas R Abstract INTRODUCTION: Low content of cell-free mitochondrial DNA (mtDNA) in cerebrospinal fluid (CSF) is a biomarker of early stage Alzheimer's disease (AD), but whether mtDNA is altered in a rapid neurodegenerative dementia such as Creutzfeldt-Jakob disease is unknown. METHODS: CSF mtDNA was measured using digital PCR in two independent cohorts comprising a total of 112 patients diagno... περισσότερα »
Dermatomyositis With or Without Anti-Melanoma Differentiation-Associated Protein 5 Antibodies: Common Interferon Signature but Distinct NOS2 Expression.
*Dermatomyositis With or Without Anti-Melanoma Differentiation-Associated Protein 5 Antibodies: Common Interferon Signature but Distinct NOS2 Expression.* Am J Pathol. 2016 Jan 21; Authors: Allenbach Y, Leroux G, Calvet XS, Preusse C, Gallardo E, Hervier B, Rigolet A, Hie M, Pehl D, Limal N, Hufnagl P, Zerbe N, Meyer A, Aouizerate J, Uzunhan Y, Maisonobe T, Goebel HH, Benveniste O, Stenzel W, French Myositis Network Abstract The anti-melanoma differentiation-associated protein 5 (MDA5) autoantibody is specifically associated with dermatomyositis (DM). Nevertheless, anti-MDA5(+)... περισσότερα »
Abnormally increased and incoherent resting-state activity is shared between patients with schizophrenia and their unaffected siblings.
*Abnormally increased and incoherent resting-state activity is shared between patients with schizophrenia and their unaffected siblings.* Schizophr Res. 2016 Jan 21; Authors: Liu C, Xue Z, Palaniyappan L, Zhou L, Liu H, Qi C, Wu G, Mwansisya TE, Tao H, Chen X, Huang X, Liu Z, Pu W Abstract BACKGROUND: Several resting-state neuroimaging studies in schizophrenia indicate an excessive brain activity while others report an incoherent brain activity at rest. No direct evidence for the simultaneous presence of both excessive and incoherent brain activity has been established to date. ...περισσότερα »
Prognostic model for long-term survival of locally advanced non-small-cell lung cancer patients after neoadjuvant radiochemotherapy and resection integrating clinical and histopathologic factors.
[image: http:--http://ift.tt/1NMOrDk] [image: http:--http://ift.tt/1Fkw4zC] Related Articles *Prognostic model for long-term survival of locally advanced non-small-cell lung cancer patients after neoadjuvant radiochemotherapy and resection integrating clinical and histopathologic factors.* BMC Cancer. 2015;15:363 Authors: Pöttgen C, Stuschke M, Graupner B, Theegarten D, Gauler T, Jendrossek V, Freitag L, Jawad JA, Gkika E, Wohlschlaeger J, Welter S, Hoiczyk M, Schuler M, Stamatis G, Eberhardt W Abstract BACKGROUND: Outcome of consecutive patients with locally advanced non-small ...περισσότερα »
Lyme carditis--diagnosis, treatment and prognosis.
[image: http:--http://ift.tt/1QysyMs] [image: http:--http://ift.tt/1Fkw4zC] Related Articles *Lyme carditis--diagnosis, treatment and prognosis.* Dtsch Arztebl Int. 2015 Mar 20;112(12):202-8 Authors: Scheffold N, Herkommer B, Kandolf R, May AE Abstract BACKGROUND: There are 60,000 to 100,000 new cases of borreliosis in Germany each year. This infectious disease most commonly affects the skin, joints, and nervous system. Lyme carditis is a rare manifestation with potentially lethal complications. METHODS: This review is based on selected publications on the clinical manifestations...περισσότερα »
Local cortical thinning links to resting-state disconnectivity in major depressive disorder.
Related Articles *Local cortical thinning links to resting-state disconnectivity in major depressive disorder.* Psychol Med. 2014 Jul;44(10):2053-65 Authors: van Tol MJ, Li M, Metzger CD, Hailla N, Horn DI, Li W, Heinze HJ, Bogerts B, Steiner J, He H, Walter M Abstract BACKGROUND: Local structural and metabolic as well as inter-regional connectivity abnormalities have been implicated in the neuropathology of major depressive disorder (MDD). How local tissue properties affect intrinsic functional connectivity is, however, unclear. Using a cross-sectional, multi-modal imaging appr... περισσότερα »
Future Oncology; +31 new citations
31 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: *Future Oncology* These pubmed results were generated on 2016/01/26 PubMed comprises more than 24 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites. from Head and Neck on PubMed via xlomafota13 on Inoreader http://ift.tt/1QysvQM via IFTTT
Assessment of rehabilitation needs in colorectal cancer treatment: Results from a mixed audit and qualitative study in Denmark.
*Assessment of rehabilitation needs in colorectal cancer treatment: Results from a mixed audit and qualitative study in Denmark.* Acta Oncol. 2016 Jan 25;:1-7 Authors: Wiedenbein L, Kristiansen M, Adamsen L, Hjort D, Hendriksen C Abstract Background Systematic assessments of cancer patients' rehabilitation needs are a prerequisite for devising appropriate survivorship programs. Little is known about the fit between needs assessment outlined in national rehabilitation policies and clinical practice. This study aimed to explore clinical practices related to identification and docum...περισσότερα »
Tumor-selective anti-cancer effects of the synthetic alkyl phosphocholine analog CLR1404 in neuroblastoma.
*Tumor-selective anti-cancer effects of the synthetic alkyl phosphocholine analog CLR1404 in neuroblastoma.* Am J Cancer Res. 2015;5(11):3422-35 Authors: Marino R, Baiu DC, Bhattacharya S, Titz B, Hebron E, Menapace BD, Singhal S, Eickhoff JC, Asimakopoulos F, Weichert JP, Otto M Abstract Neuroblastoma (NB) is the most common extracranial solid tumor in children and is associated with high mortality in advanced stages. Survivors suffer from long-term treatment-related sequelae. Thus, new targeted treatment options are urgently needed. 18-(p-[(127)I] iodophenyl) octadecyl phospho...περισσότερα »
Thyroid carcinoma in children, adolescents and adults, both spontaneous and after childhood radiation exposure.
*Thyroid carcinoma in children, adolescents and adults, both spontaneous and after childhood radiation exposure.* Eur J Pediatr. 2016 Jan 25; Authors: Ho WL, Zacharin MR Abstract Thyroid carcinoma is the most common second malignancy for childhood cancer survivors. Radiation exposure is linked to risk. Thyroid nodules in children have a high risk for malignancy, whether spontaneous or after radiation. Due to the extremely limited available paediatric data, we sought to review a series of patients with thyroid carcinoma, seen over 25 years. Forty-six patients were identified. Thi... περισσότερα »
CT scan findings do not predict outcome of nonoperative management in small bowel obstruction.
*CT scan findings do not predict outcome of nonoperative management in small bowel obstruction.* Int J Surg. 2016 Jan 22; Authors: Pricolo VE, Curley F Abstract OBJECTIVES: The study purpose was to investigate the ability of Emergency Department CT scan to predict the need for operative intervention in patients hospitalized for small bowel obstruction (SBO) likely secondary to adhesions (ASBO) and initially managed nonoperatively. DESIGN: Retrospective case series. Statistical analysis was done with independent-samples t-test and chi-square to identify correlation between variab... περισσότερα »
Genetic variants in VEGF pathway genes in neoadjuvant breast cancer patients receiving bevacizumab: Results from the randomized phase III GeparQuinto study.
[image: http:--media.wiley.com-assets-7315-19-Wi] [image: http:--media.wiley.com-assets-7315-19-Wi] Related Articles *Genetic variants in VEGF pathway genes in neoadjuvant breast cancer patients receiving bevacizumab: Results from the randomized phase III GeparQuinto study.* Int J Cancer. 2015 Dec 15;137(12):2981-8 Authors: Hein A, Lambrechts D, von Minckwitz G, Häberle L, Eidtmann H, Tesch H, Untch M, Hilfrich J, Schem C, Rezai M, Gerber B, Dan Costa S, Blohmer JU, Schwedler K, Kittel K, Fehm T, Kunz G, Beckmann MW, Ekici AB, Hanusch C, Huober J, Liedtke C, Mau C, Moisse M, Müll... περισσότερα »
Primary pineal malignant melanoma with B-Raf V600E mutation: a case report and brief review of the literature.
[image: http:--production.springer.de-OnlineReso] Related Articles *Primary pineal malignant melanoma with B-Raf V600E mutation: a case report and brief review of the literature.* Acta Neurochir (Wien). 2015 Jul;157(7):1267-70 Authors: Jetschke K, Viehweger H, Freesmeyer M, Warnke JP, Mawrin C Abstract Primary pineal melanoma is exceedingly rare, and sufficient treatment options have not been established. Here we describe a 57-year-old male patient who presented with short-term memory disturbance and ataxia. Magnetic resonance imaging of the brain showed a tumor mass in the pineal...περισσότερα »
Selectively false-positive radionuclide scan in a patient with sarcoidosis and papillary thyroid cancer: a case report and review of the literature.
[image: http:--http://ift.tt/1NMOrDk] [image: http:--http://ift.tt/1Fkw4zC] Related Articles *Selectively false-positive radionuclide scan in a patient with sarcoidosis and papillary thyroid cancer: a case report and review of the literature.* J Otolaryngol Head Neck Surg. 2015;44:18 Authors: Lebo NL, Raymond F, Odell MJ Abstract BACKGROUND: Radioiodine and Tc-99 m pertechnetate scans are routinely relied upon to detect metastasis in papillary thyroid cancer; false-positive scans are relatively rare. To our knowledge, no published reports exist of sarcoidosis causing such selecti... περισσότερα »
Warthin's tumor of the larynx: a very rare case and systematic review of the literature.
[image: http:--http://ift.tt/1NMOrDk] [image: http:--http://ift.tt/1Fkw4zC] Related Articles *Warthin's tumor of the larynx: a very rare case and systematic review of the literature.* J Otolaryngol Head Neck Surg. 2015;44:16 Authors: Nisa L, Landis BN, Salmina C, Ailianou A, Karamitopoulou E, Giger R Abstract BACKGROUND: Warthin's tumor or cystadenolymphoma (CAL) is a benign salivary gland tumor occurring almost exclusively in the parotid gland. CALs of other locations are rare. CASE PRESENTATION: We report a laryngeal CAL detected in a positron emission tomography/computed tomog...περισσότερα »
Management of an expansile orbital mass: Plexiform neurofibroma decompression by orbitozygomatic approach.
[image: http:--media.wiley.com-assets-7315-19-Wi] Related Articles *Management of an expansile orbital mass: Plexiform neurofibroma decompression by orbitozygomatic approach.* Laryngoscope. 2015 Nov;125(11):2457-60 Authors: Kovatch KJ, Purkey MT, Martinez-Lage M, Gausas RE, Loevner LA, Grady MS, O'Malley BW, Rassekh CH Abstract Neurofibromatosis types 1 (NF-1) and 2 are significant entities to otolaryngologists because they frequently involve head and neck skin, brain, skull base, orbits, and surrounding neural and vascular structures. We present the case of a 52-year-old male wi...περισσότερα »
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Publication date: Available online 25 January 2016 *Source:*Journal of Oral and Maxillofacial Surgery from #ΓναθοΧειρουργική via xlomafota13 on Inoreader http://ift.tt/2016RLc via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
Condylar Erosion In Patients With Chronic Temporomandibular Joint Arthralgia: A Cone Beam Computed Tomography Study
Publication date: Available online 25 January 2016 *Source:*Journal of Oral and Maxillofacial Surgery Author(s): Emshoff Rüdiger, Bertram Felix, Schnabl Dagmar, Stigler Robert, Steinmaßl Otto, Ansgar Rudisch PurposeThe objective of this study was to assess the association between temporomandibular joint (TMJ) condylar erosion and chronic TMJ arthralgia.Material and MethodsBased upon a sample size estimation, this case–control study involved 198 subjects, aged 16–73, recruited in routine clinical practice; 99 cases (chronic TMJ arthralgia patients with a mean pain duration of 16.4 mo... περισσότερα »
Andreas Vesalius' 500th Anniversary: Initial Integral Understanding of Voice Production.
Andreas Vesalius' 500th Anniversary: Initial Integral Understanding of Voice Production.: *Andreas Vesalius' 500th Anniversary: Initial Integral Understanding of Voice Production.* J Voice. 2016 Jan 21; Authors: Brinkman RJ, Hage JJ Abstract BACKGROUND: Voice production relies on the integrated functioning of a three-part system: respiration, phonation and resonance, and articulation. To commemorate the 500th anniversary of the great anatomist Andreas Vesalius (1515-1564), we report on his understanding of this integral system. METHODS: The text of Vesalius' masterpiece De Huma...περισσότερα »
DACH1 inhibits the proliferation and invasion of lung adenocarcinoma through the downregulation of peroxiredoxin 3
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 40 δευτερόλεπτα
Abstract In this study, we found the expression of Dachshund 1 (DACH1) is downregulated while peroxiredoxin 3 (PRX3) upregulated in both lung adenocarcinoma tissues and cells. Transfection of DACH1 can significantly downregulate PRX3 expression in targeting lung adenocarcinoma cells. Further experimental results demonstrated the evidence that overexpression of DACH1 resulted in significant retardation of in […]
RT @RCSnews : The aim of RCS Educational Leadership Programme is to develop surgeons to become leaders, https: //t.co/3NhOpYhuNH https://t.co…
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 40 δευτερόλεπτα
RT @RCSnews : The aim of RCS Educational Leadership Programme is to develop surgeons to become leaders, https://t.co/3NhOpYhuNH https://t.co… from #ORL-AlexandrosSfakianakis via simeraentaxei on Inoreader http://twitter.com/ecancer/status/691946148131672065 via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174 from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1nl5Lbo via IFTTT
The far-upstream element-binding protein 2 is correlated with proliferation and doxorubicin resistance in human breast cancer cell lines
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 40 δευτερόλεπτα
Abstract Far-upstream element (FUSE)-binding protein 2 (FBP2) was a member of single-stranded DNA-binding protein family; it played an important role in regulating transcription and post-transcription and is involved in the regulation of C-MYC gene expression in liver tumors. However, the role of FBP2 in breast cancer and its mechanism has not been studied yet. Here, […]
GRIM-19 inhibition induced autophagy through activation of ERK and HIF-1α not STAT3 in Hela cells
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 40 δευτερόλεπτα
Abstract Gene associated with retinoid-interferon-induced mortality (GRIM-19), an important subunit of mitochondrial complex I, has been identified as a tumor suppressor, and its reduced expression has been reported to be associated with tumorigenesis and metastasis. Autophagy has been proposed as a protective mechanism for cell survival under various stresses, including chemotherapy. However, it remains unknown […]
Tumor-selective anti-cancer effects of the synthetic alkyl phosphocholine analog CLR1404 in neuroblastoma.
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 40 δευτερόλεπτα
Tumor-selective anti-cancer effects of the synthetic alkyl phosphocholine analog CLR1404 in neuroblastoma. Am J Cancer Res. 2015;5(11):3422-35 Authors: Marino R, Baiu DC, Bhattacharya S, Titz B, Hebron E, Menapace BD, Singhal S, Eickhoff JC, Asimakopoulos F, Weichert JP, Otto M Abstract Neuroblastoma (NB) is the most common extracranial solid tumor in children and is associated […]
Isolated Vestibular Suppression Impairment With Vestibular Migraine: A Phenotypic CANVAS Variant.
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 40 δευτερόλεπτα
Isolated Vestibular Suppression Impairment With Vestibular Migraine: A Phenotypic CANVAS Variant. Otol Neurotol. 2016 Jan 20; Authors: Migliaccio AA, Watson SR Abstract HYPOTHESIS: Cerebellar Ataxia with Neuropathy and Vestibular Areflexia (CANVAS) is likely to have a genetic basis. We describe the unique eye movement features of a possible phenotypic CANVAS variant. BACKGROUND: The patient comes […]
Overweight and obesity predict better overall survival rates in cancer patients with distant metastases
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 40 δευτερόλεπτα
Abstract Recent studies conducted in patients with chronic diseases have reported an inverse association between body mass index (BMI) and mortality. However, the question as to whether BMI may predict prognosis in patients with metastatic cancer remains open. We therefore designed the current retrospective study to investigate the potential association between BMI and overall survival […]
Sanna Classification and Prognosis of Cholesteatoma of the Petrous Part of the Temporal Bone: A Retrospective Series of 81 Patients.
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 40 δευτερόλεπτα
Sanna Classification and Prognosis of Cholesteatoma of the Petrous Part of the Temporal Bone: A Retrospective Series of 81 Patients. Otol Neurotol. 2016 Jan 20; Authors: Danesi G, Cooper T, Panciera DT, Manni V, Côté DW Abstract OBJECTIVE: To determine how classification of petrous bone cholesteatomas (PBCs) using the 5-point Sanna classification can predict major […]
A comparative analysis of ESM-1 and vascular endothelial cell marker (CD34/CD105) expression on pituitary adenoma invasion
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 40 δευτερόλεπτα
Abstract Objective Pituitary adenomas are benign neoplasms that display invasive behavior—a characteristic traditionally associated with malignancy—through an ill-defined mechanism. The role of angiogenesis-related molecules in this pathological condition remains perplexing. Our purpose is to assess the impact of endocan (endothelial cell specific molecule-1, ESM-1), CD34 and CD105 on pituitary adenoma invasion. Methods In this study, […]
Prognostic model for long-term survival of locally advanced non-small-cell lung cancer patients after neoadjuvant radiochemotherapy and resection integrating clinical and histopathologic factors.
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 40 δευτερόλεπτα
Related Articles Prognostic model for long-term survival of locally advanced non-small-cell lung cancer patients after neoadjuvant radiochemotherapy and resection integrating clinical and histopathologic factors. BMC Cancer. 2015;15:363 Authors: Pöttgen C, Stuschke M, Graupner B, Theegarten D, Gauler T, Jendrossek V, Freitag L, Jawad JA, Gkika E, Wohlschlaeger J, Welter S, Hoiczyk M, Schuler M, Stamatis […]
Sanna Classification and Prognosis of Cholesteatoma of the Petrous Part of the Temporal Bone
Sanna Classification and Prognosis of Cholesteatoma of the Petrous Part of the Temporal Bone: A Retrospective Series of 81 Patients.: *Sanna Classification and Prognosis of Cholesteatoma of the Petrous Part of the Temporal Bone: A Retrospective Series of 81 Patients.* Otol Neurotol. 2016 Jan 20; Authors: Danesi G, Cooper T, Panciera DT, Manni V, Côté DW Abstract OBJECTIVE: To determine how classification of petrous bone cholesteatomas (PBCs) using the 5-point Sanna classification can predict major structural involvement, facial nerve outcomes, hearing outcomes, postoperative comp...περισσότερα »
Translational research on influenza virus infection using a nonhuman primate model
Alexandros G. SfakianakisστοCell and Tissue Research by Alexandros G. SfakianakisΠριν από 41 δευτερόλεπτα
Influenza virus infection is a seasonal infectious disease for humans, whereas it is also a zoonosis that is originally transmitted from animals to humans. Therefore, several animal models are used in research on influenza virus infection. We have used a nonhuman primate (NHP) model to extrapolate pathogenicity of various influenza viruses and efficacy of vaccines and antiviral drugs against the influenza viruses in humans. NHPs have genes, anatomical structure, and immune responses similar to those of humans as compared to other animal models. Using an NHP model, we revealed tha...περισσότερα »
Interaction between thyrocytes and adipose tissue in vitro
Alexandros G. SfakianakisστοCell and Tissue Research by Alexandros G. SfakianakisΠριν από 41 δευτερόλεπτα
Adipose tissue (AT)-thyrocyte interaction is largely unknown. Here we described the interaction in a co-culture system, in which thyrocytes were cultured on AT fragment (ATF)-embedded collagen gel, using electron microscopy, immunocytochemistry, real-time reverse transcription–polymerase chain reaction (RT–PCR) and enzyme-linked immunosorbent assay (ELISA). ATFs promoted the hypertrophy, polarization and lipid accumulation of thyrocytes. ATFs did not affect the growth of thyroyctes, and inhibited their apoptosis. ATFs increased the protein expression of thyroglobulin (Tg) and pai... περισσότερα »
Comprehensive profiling reveals mechanisms of SOX2-mediated cell fate specification in human ESCs and NPCs
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 48 δευτερόλεπτα
Comprehensive profiling reveals mechanisms of SOX2-mediated cell fate specification in human ESCs and NPCs Cell Research advance online publication, January 26 2016. doi:10.1038/cr.2016.15 Authors: Chenlin Zhou, Xiaoqin Yang, Yiyang Sun, Hongyao Yu, Yong Zhang & Ying Jin from #ORL-AlexandrosSfakianakis via simeraentaxei on Inoreader http://ift.tt/1PzU1yn via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 […]
Register now for our #prostate cancer conference in Argentina! https://t.co/MCmu9qjs2D @ecancer_espanol https://t.co/JSptK0k4m0
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 48 δευτερόλεπτα
Register now for our #prostate cancer conference in Argentina! https://t.co/MCmu9qjs2D @ecancer_espanol https://t.co/JSptK0k4m0 from #ORL-AlexandrosSfakianakis via simeraentaxei on Inoreader http://twitter.com/ecancer/status/691946316897861633 via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
RT @RCSnews : The aim of RCS Educational Leadership Programme is to develop surgeons to become leaders, https: //t.co/3NhOpYhuNH https://t.co…
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 48 δευτερόλεπτα
RT @RCSnews : The aim of RCS Educational Leadership Programme is to develop surgeons to become leaders, https://t.co/3NhOpYhuNH https://t.co… from #ORL-AlexandrosSfakianakis via simeraentaxei on Inoreader http://twitter.com/ecancer/status/691946148131672065 via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
Possibility for sustained disease control in about 20% of patients with alisertib for pretreated urothelial cancer https://t.co/hGfLxJd5Ol
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 48 δευτερόλεπτα
Possibility for sustained disease control in about 20% of patients with alisertib for pretreated urothelial cancer https://t.co/hGfLxJd5Ol from #ORL-AlexandrosSfakianakis via simeraentaxei on Inoreader http://twitter.com/ecancer/status/691941944398843905 via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
Help to make the UK tobacco industry ‘cough up’ and pay for public health campaigns https://t.co/D0vIb2CKK3
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 48 δευτερόλεπτα
Help to make the UK tobacco industry ‘cough up’ and pay for public health campaigns https://t.co/D0vIb2CKK3 from #ORL-AlexandrosSfakianakis via simeraentaxei on Inoreader http://twitter.com/ecancer/status/691926844581507072 via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
Prof Matthew Galsky explains how a combination of immunotherapy plus chemotherapy may treat bladder cancer: https://t.co/r5bSt8TcvY
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 48 δευτερόλεπτα
Prof Matthew Galsky explains how a combination of immunotherapy plus chemotherapy may treat bladder cancer: https://t.co/r5bSt8TcvY from #ORL-AlexandrosSfakianakis via simeraentaxei on Inoreader http://twitter.com/ecancer/status/691926521854967808 via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
A genetic change often lost in childhood cancer is crucial in cells’ life or death decision https://t.co/NPzCUDGVOO
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 48 δευτερόλεπτα
A genetic change often lost in childhood cancer is crucial in cells’ life or death decision https://t.co/NPzCUDGVOO from #ORL-AlexandrosSfakianakis via simeraentaxei on Inoreader http://twitter.com/ecancer/status/691926199480782848 via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
Scientists synthesise nanoparticles that can deliver tumour suppressors to damaged livers
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 48 δευτερόλεπτα
UT Southwestern Medical Center chemists have successfully used synthetic nanoparticles to deliver tumour-suppressing therapies to diseased livers with cancer, an important hurdle scientists have been struggling to conquer. Late-stage liver cancer is a… from #ORL-AlexandrosSfakianakis via simeraentaxei on Inoreader http://ift.tt/20qrrBr via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
Afatinib shows clinical benefit for lung cancer patients with brain metastases
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 48 δευτερόλεπτα
Non-small cell lung cancer (NSCLC) patients with common epidermal growth factor (EGFR) mutations and brain metastases showed improved progression-free survival (PFS) and response from the EGFR tyrosine kinase inhibitor (TKI) afatinib compared to standard… from #ORL-AlexandrosSfakianakis via simeraentaxei on Inoreader http://ift.tt/20qrtck via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
Microscopic drug ‘depots’ boost efficacy against tumors in animal model
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 48 δευτερόλεπτα
Biomedical engineering researchers have developed a technique for creating microscopic «depots» for trapping drugs inside cancer tumours. In an animal model, these drug depots were 10 times more effective at shrinking tumours than the use of the same… from #ORL-AlexandrosSfakianakis via simeraentaxei on Inoreader http://ift.tt/1QyrTeb via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel […]
Erratum: Development, appraisal, validation and implementation of a consensus protocol for the assessment of cerebral amyloid angiopathy in post-mortem brain tissue.
*Erratum: Development, appraisal, validation and implementation of a consensus protocol for the assessment of cerebral amyloid angiopathy in post-mortem brain tissue.* Am J Neurodegener Dis. 2015;4(2):49 Authors: Love S, Chalmers K, Ince P, Esiri M, Attems J, Kalaria R, Jellinger K, Yamada M, McCarron M, Minett T, Matthews F, Greenberg S, Mann D, Kehoe PG Abstract In a collaboration involving 11 groups with research interests in cerebral amyloid angiopathy (CAA), we used a two-stage process to develop and in turn validate a new consensus protocol and scoring scheme for the asse...περισσότερα »
Mitochondrial DNA differentiates Alzheimer from Creutzfeldt-Jakob disease.
*Mitochondrial DNA differentiates Alzheimer from Creutzfeldt-Jakob disease.* Alzheimers Dement. 2016 Jan 21; Authors: Podlesniy P, Llorens F, Golanska E, Sikorska B, Liberski P, Zerr I, Trullas R Abstract INTRODUCTION: Low content of cell-free mitochondrial DNA (mtDNA) in cerebrospinal fluid (CSF) is a biomarker of early stage Alzheimer's disease (AD), but whether mtDNA is altered in a rapid neurodegenerative dementia such as Creutzfeldt-Jakob disease is unknown. METHODS: CSF mtDNA was measured using digital PCR in two independent cohorts comprising a total of 112 patients diagno... περισσότερα »
Dermatomyositis With or Without Anti-Melanoma Differentiation-Associated Protein 5 Antibodies: Common Interferon Signature but Distinct NOS2 Expression.
*Dermatomyositis With or Without Anti-Melanoma Differentiation-Associated Protein 5 Antibodies: Common Interferon Signature but Distinct NOS2 Expression.* Am J Pathol. 2016 Jan 21; Authors: Allenbach Y, Leroux G, Calvet XS, Preusse C, Gallardo E, Hervier B, Rigolet A, Hie M, Pehl D, Limal N, Hufnagl P, Zerbe N, Meyer A, Aouizerate J, Uzunhan Y, Maisonobe T, Goebel HH, Benveniste O, Stenzel W, French Myositis Network Abstract The anti-melanoma differentiation-associated protein 5 (MDA5) autoantibody is specifically associated with dermatomyositis (DM). Nevertheless, anti-MDA5(+)... περισσότερα »
Abnormally increased and incoherent resting-state activity is shared between patients with schizophrenia and their unaffected siblings.
*Abnormally increased and incoherent resting-state activity is shared between patients with schizophrenia and their unaffected siblings.* Schizophr Res. 2016 Jan 21; Authors: Liu C, Xue Z, Palaniyappan L, Zhou L, Liu H, Qi C, Wu G, Mwansisya TE, Tao H, Chen X, Huang X, Liu Z, Pu W Abstract BACKGROUND: Several resting-state neuroimaging studies in schizophrenia indicate an excessive brain activity while others report an incoherent brain activity at rest. No direct evidence for the simultaneous presence of both excessive and incoherent brain activity has been established to date. ...περισσότερα »
Prognostic model for long-term survival of locally advanced non-small-cell lung cancer patients after neoadjuvant radiochemotherapy and resection integrating clinical and histopathologic factors.
[image: http:--http://ift.tt/1NMOrDk] [image: http:--http://ift.tt/1Fkw4zC] Related Articles *Prognostic model for long-term survival of locally advanced non-small-cell lung cancer patients after neoadjuvant radiochemotherapy and resection integrating clinical and histopathologic factors.* BMC Cancer. 2015;15:363 Authors: Pöttgen C, Stuschke M, Graupner B, Theegarten D, Gauler T, Jendrossek V, Freitag L, Jawad JA, Gkika E, Wohlschlaeger J, Welter S, Hoiczyk M, Schuler M, Stamatis G, Eberhardt W Abstract BACKGROUND: Outcome of consecutive patients with locally advanced non-small ...περισσότερα »
Lyme carditis--diagnosis, treatment and prognosis.
[image: http:--http://ift.tt/1QysyMs] [image: http:--http://ift.tt/1Fkw4zC] Related Articles *Lyme carditis--diagnosis, treatment and prognosis.* Dtsch Arztebl Int. 2015 Mar 20;112(12):202-8 Authors: Scheffold N, Herkommer B, Kandolf R, May AE Abstract BACKGROUND: There are 60,000 to 100,000 new cases of borreliosis in Germany each year. This infectious disease most commonly affects the skin, joints, and nervous system. Lyme carditis is a rare manifestation with potentially lethal complications. METHODS: This review is based on selected publications on the clinical manifestations...περισσότερα »
Local cortical thinning links to resting-state disconnectivity in major depressive disorder.
Related Articles *Local cortical thinning links to resting-state disconnectivity in major depressive disorder.* Psychol Med. 2014 Jul;44(10):2053-65 Authors: van Tol MJ, Li M, Metzger CD, Hailla N, Horn DI, Li W, Heinze HJ, Bogerts B, Steiner J, He H, Walter M Abstract BACKGROUND: Local structural and metabolic as well as inter-regional connectivity abnormalities have been implicated in the neuropathology of major depressive disorder (MDD). How local tissue properties affect intrinsic functional connectivity is, however, unclear. Using a cross-sectional, multi-modal imaging appr... περισσότερα »
Future Oncology; +31 new citations
31 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: *Future Oncology* These pubmed results were generated on 2016/01/26 PubMed comprises more than 24 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites. from #PubMed 3 via ola Kala on Inoreader http://ift.tt/1QysvQM via IFTTT
Identification of Biomarkers by Proteomics for Prenatal Screening for Neural Tube Defects.
*Identification of Biomarkers by Proteomics for Prenatal Screening for Neural Tube Defects.* Tohoku J Exp Med. 2016;238(2):123-9 Authors: Shen G, He P, Du Y, Zhang S Abstract Neural tube defect (NTD) is a serious congenital defect, but current methods for identifying NTD are limited. We used proteomic analysis of maternal serum to identify NTD-specific proteins whose levels differed between women with NTD fetuses (n = 50) and those with healthy fetuses (n = 40). Three NTD-specific protein peaks (8,130.6, 15,941.7, and 3,960.3 m/z) were identified using MALDI-TOF-mass spectrophot...περισσότερα »
Influenza Virus Shedding in Laninamivir-Treated Children upon Returning to School.
*Influenza Virus Shedding in Laninamivir-Treated Children upon Returning to School.* Tohoku J Exp Med. 2016;238(2):113-21 Authors: Kondo H, Shobugawa Y, Hibino A, Yagami R, Dapat C, Okazaki M, Otsuka T, Fujii K, Hassan MR, Saito R Abstract The current School Health and Safety Act in Japan states that children with influenza infection should stay home until day 6(th) after symptoms onset. This was an amendment of a previous version recommending school return on day 3 after defervescence. Here, we investigated the duration of fever and virus shedding after laninamivir treatment in...περισσότερα »
Assessment of rehabilitation needs in colorectal cancer treatment: Results from a mixed audit and qualitative study in Denmark.
*Assessment of rehabilitation needs in colorectal cancer treatment: Results from a mixed audit and qualitative study in Denmark.* Acta Oncol. 2016 Jan 25;:1-7 Authors: Wiedenbein L, Kristiansen M, Adamsen L, Hjort D, Hendriksen C Abstract Background Systematic assessments of cancer patients' rehabilitation needs are a prerequisite for devising appropriate survivorship programs. Little is known about the fit between needs assessment outlined in national rehabilitation policies and clinical practice. This study aimed to explore clinical practices related to identification and docum...περισσότερα »
[Treatment Strategy for Gastric Carcinoma with Lymphoid Stroma].
*[Treatment Strategy for Gastric Carcinoma with Lymphoid Stroma].* Gan To Kagaku Ryoho. 2015 Nov;42(12):2021-3 Authors: Kobayashi R, Takiguchi N, Nabeya Y, Ikeda A, Souda H, Kainuma O, Tonooka T, Imanishi S, Arimitsu H, Chibana T, Ishige F, Sasaki K, Yamamoto H Abstract Gastric carcinoma with lymphoid stroma(GCLS)is a histological type with severe lymphocytic infiltration. GCLS is very rare and few cases have been reported. We examined the clinical features, problems of preoperative diagnosis, and treatment of 14 cases(1.8%)that were diagnosed as GCLS out of 790 gastric cancers s... περισσότερα »
[Basaloid Carcinoma of the Esophagus with Lugol-Voiding Lesions-A Case Report].
*[Basaloid Carcinoma of the Esophagus with Lugol-Voiding Lesions-A Case Report].* Gan To Kagaku Ryoho. 2015 Nov;42(12):1899-901 Authors: Shimakawa T, Asaka S, Shimazaki A, Yamaguchi K, Usui T, Yokomizo H, Shiozawa S, Yoshimatsu K, Katsube T, Naritaka Y, Fujibayashi M Abstract Patients with Lugol-voiding lesions of the esophagus are frequently affected with multiple cancers. Basaloid carcinoma of the esophagus is a very rare disease characterized by growth in the submucosal layer that exhibits a submucosal tumor-like shape. There have been some reports that this type of carcinoma... περισσότερα »
Tumor-selective anti-cancer effects of the synthetic alkyl phosphocholine analog CLR1404 in neuroblastoma.
*Tumor-selective anti-cancer effects of the synthetic alkyl phosphocholine analog CLR1404 in neuroblastoma.* Am J Cancer Res. 2015;5(11):3422-35 Authors: Marino R, Baiu DC, Bhattacharya S, Titz B, Hebron E, Menapace BD, Singhal S, Eickhoff JC, Asimakopoulos F, Weichert JP, Otto M Abstract Neuroblastoma (NB) is the most common extracranial solid tumor in children and is associated with high mortality in advanced stages. Survivors suffer from long-term treatment-related sequelae. Thus, new targeted treatment options are urgently needed. 18-(p-[(127)I] iodophenyl) octadecyl phospho...περισσότερα »
Thyroid carcinoma in children, adolescents and adults, both spontaneous and after childhood radiation exposure.
*Thyroid carcinoma in children, adolescents and adults, both spontaneous and after childhood radiation exposure.* Eur J Pediatr. 2016 Jan 25; Authors: Ho WL, Zacharin MR Abstract Thyroid carcinoma is the most common second malignancy for childhood cancer survivors. Radiation exposure is linked to risk. Thyroid nodules in children have a high risk for malignancy, whether spontaneous or after radiation. Due to the extremely limited available paediatric data, we sought to review a series of patients with thyroid carcinoma, seen over 25 years. Forty-six patients were identified. Thi... περισσότερα »
upper respiratory tract infection; +112 new citations
112 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: *upper respiratory tract infection* These pubmed results were generated on 2016/01/26 PubMed comprises more than 24 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites. from #PubMed 2 via ola Kala on Inoreader http://ift.tt/1PyHqFm via IFTTT
Vascular anomalies of the head and neck in children.
*Vascular anomalies of the head and neck in children.* Quant Imaging Med Surg. 2015 Dec;5(6):886-97 Authors: Mahady K, Thust S, Berkeley R, Stuart S, Barnacle A, Robertson F, Mankad K Abstract Sixty percent of vascular anomalies in children are found in the head and neck. These lesions can present throughout antenatal, perinatal and childhood development. They broadly fall into two categories: vascular tumours and vascular malformations. Their clinical and, often, psychological impact is determined by both pathological type and location: many lesions follow an uncomplicated natu... περισσότερα »
Effects of EZH2 promoter polymorphisms and methylation status on oral squamous cell carcinoma susceptibility and pathology.
*Effects of EZH2 promoter polymorphisms and methylation status on oral squamous cell carcinoma susceptibility and pathology.* Am J Cancer Res. 2015;5(11):3475-84 Authors: Su KJ, Lin CW, Chen MK, Yang SF, Yu YL Abstract Oral squamous cell carcinoma (OSCC), which is malignant tumors in oral cavity, is the fourth most common male cancer in Taiwan. EZH2 plays a key role in transcriptional repression through chromatin remodeling and in cancer development. Although the EZH2 expression in OSCC is highly correlated with tumorigenesis, it has not been determined if specific EZH2 genetic ... περισσότερα »
Activation of K(+) channel by 1-EBIO rescues the head and neck squamous cell carcinoma cells from Ca(2+) ionophore-induced cell death.
*Activation of K(+) channel by 1-EBIO rescues the head and neck squamous cell carcinoma cells from Ca(2+) ionophore-induced cell death.* Korean J Physiol Pharmacol. 2016 Jan;20(1):25-33 Authors: Yin MZ, Park SW, Kang TW, Kim KS, Yoo HY, Lee J, Hah JH, Sung MH, Kim SJ Abstract Ion channels in carcinoma and their roles in cell proliferation are drawing attention. Intracellular Ca(2+) ([Ca(2+)]i)-dependent signaling affects the fate of cancer cells. Here we investigate the role of Ca(2+)-activated K(+) channel (SK4) in head and neck squamous cell carcinoma cells (HNSCCs) of differe... περισσότερα »
Effects of Antioxidants in Human Cancers: Differential Effects on Non-Coding Intronic RNA Expression.
*Effects of Antioxidants in Human Cancers: Differential Effects on Non-Coding Intronic RNA Expression.* Antioxidants (Basel). 2016;5(1) Authors: Menon S, Lu C, Menon R, Schwartz J, Guan Y Abstract The notion that dietary antioxidants can help fight cancer is popular. However, the mechanism(s) behind the effect of antioxidants in cancer is still unclear. Previous studies indicate that supplements can influence gene expression; however, all of these studies were focused on the coding/exonic gene expression. Studies are now emerging to highlight critical functional roles for RNAs e... περισσότερα »
[Palliative Care for Rectal Cancer Complicated with Gastric Cancer].
*[Palliative Care for Rectal Cancer Complicated with Gastric Cancer].* Gan To Kagaku Ryoho. 2015 Nov;42(12):2273-5 Authors: Furukawa T, Takahashi H, Tanaka K, Muto T Abstract Medical advancements have led to an increase in the number of elderly people. However, standard treatments may sometimes be difficult to use in elderly people. Here, we report the case of an elderly patient with rectal and gastric cancer who refused radical surgery. The patient was an 83-year-old man who had type-2 diabetes, hypertension, hyperuricemia, mitral valve regurgitation, and mild dementia. Furtherm...περισσότερα »
Adherence to the world cancer research fund/american institute for cancer research recommendations and breast cancer risk.
*Adherence to the world cancer research fund/american institute for cancer research recommendations and breast cancer risk.* Int J Cancer. 2016 Jan 25; Authors: Harris HR, Bergkvist L, Wolk A Abstract The World Cancer Research Fund/American Association for Cancer Research (WCRF/AICR) has published 8 nutrition-related recommendations for the prevention of cancer. However, few prospective studies have examined these recommendations by breast cancer hormone receptor subtype and only one case-control study has included the dietary supplements recommendation in their evaluation. We i... περισσότερα »
Unmetabolized Folic Acid in Prediagnostic Plasma and the Risk of Colorectal Cancer.
[image: http:--highwire.stanford.edu-icons-exter] Related Articles *Unmetabolized Folic Acid in Prediagnostic Plasma and the Risk of Colorectal Cancer.* J Natl Cancer Inst. 2015 Dec;107(12):djv260 Authors: Cho E, Zhang X, Townsend MK, Selhub J, Paul L, Rosner B, Fuchs CS, Willett WC, Giovannucci EL Abstract Higher folate has been associated with a reduced colorectal cancer (CRC) risk, but excessive folate may promote tumor progression. The role of unmetabolized folic acid (UFA) from high folic acid consumption in carcinogenesis is largely unexplored. We evaluated prediagnostic pl...περισσότερα »
The effect of six months of elastic band resistance training, nutritional supplementation or cognitive training on chromosomal damage in institutionalized elderly.
[image: http:--linkinghub.elsevier.com-ihub-imag] Related Articles *The effect of six months of elastic band resistance training, nutritional supplementation or cognitive training on chromosomal damage in institutionalized elderly.* Exp Gerontol. 2015 May;65:16-22 Authors: Franzke B, Halper B, Hofmann M, Oesen S, Pierson B, Cremer A, Bacher E, Fuchs B, Baierl A, Tosevska A, Strasser EM, Wessner B, Wagner KH, Vienna Active Ageing Study Group (VAAS) Abstract Increased DNA and chromosomal damage are linked to aging and age-related diseases like cardiovascular diseases, diabetes or c...περισσότερα »
Resident Fatigue in Otolaryngology Residents: a Web Based Survey
otolaryngologistsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.Alexandros,,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,tel : 00302841026182,00306932607174Πριν από 50 δευτερόλεπτα
Publication date: Available online 25 January 2016 Source:American Journal of Otolaryngology Author(s): Andrew M. Nida, Benjamin J. Googe, Andrea F. Lewis, Warren L. May ImportanceResident fatigue has become a point of emphasis in medical education and its effects on otolaryngology residents and their patients requires further study.ObjectiveThe purpose of our study was to evaluate the […]
Ultrasonic Bone Aspirator Assisted Endoscopic Dacryocystorhinostomy
otolaryngologistsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.Alexandros,,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,tel : 00302841026182,00306932607174Πριν από 50 δευτερόλεπτα
Publication date: Available online 25 January 2016 Source:American Journal of Otolaryngology Author(s): Toby O. Steele, Machelle Wilson, E. Bradley Strong ObjectiveTo evaluate the ultrasonic bone aspirator versus traditional powered drill technique for use in endoscopic dacryocystorhinostomy.Study DesignRetrospective chart reviewSettingAcademic InstitutionSubjects and MethodsA retrospective chart review of all patients undergoing endoscopic dacryocystorhinostomy from June 2010 through […]
Ex Vivo Ovine Model for Head and Neck Surgical Simulation
otolaryngologistsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.Alexandros,,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,tel : 00302841026182,00306932607174Πριν από 50 δευτερόλεπτα
Publication date: Available online 25 January 2016 Source:American Journal of Otolaryngology Author(s): David C. Ianacone, Beverly J. Gnadt, Glenn Isaacson ObjectiveTo evaluate a fresh, ovine/sheep head and neck tissue model to teach Otolaryngology-Head and Neck surgical techniques.Study DesignObservational animal studySettingA university animal resource facilityMethodsTissue was collected from pre-pubescent sheep (n = 10; mean age: 4 […]
Persistently high exhaled nitric oxide and loss of lung function in controlled asthma
otolaryngologistsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.Alexandros,,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,tel : 00302841026182,00306932607174Πριν από 50 δευτερόλεπτα
Publication date: Available online 25 January 2016 Source:Allergology International Author(s): Kazuto Matsunaga, Tsunahiko Hirano, Asako Oka, Kousuke Ito, Nobutaka Edakuni BackgroundsIt remains unclear whether a persistently high exhaled nitric oxide fraction (FeNO) in patients with controlled asthma is associated with the progressive loss of lung function.MethodsThis was a 3-year prospective study. We examined the changes […]
Diabetes and Periodontitis—A Dental Hygienist’s Perspective
otolaryngologistsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.Alexandros,,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,tel : 00302841026182,00306932607174Πριν από 50 δευτερόλεπτα
Abstract Several decades of research of the interrelationships between diabetes and periodontitis have evolved into a significant body of knowledge that should be incorporated into dental practice. However, there may be a delay in implementing this important information into everyday patient care. Oral healthcare providers (i.e., dentists and dental hygienists) should be progressively engaged in […]
Partynight outcome.
otolaryngologistsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.Alexandros,,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,tel : 00302841026182,00306932607174Πριν από 50 δευτερόλεπτα
Related Articles [Partynight outcome]. Dtsch Med Wochenschr. 2015 Oct;140(21):1611-3 Authors: Wunder AF, Oelckers M, Lock G Abstract HISTORY AND CLINICAL FINDINGS: An 18 year old girl was admitted with progressive painful dysphagia and a severe hemorrhagic endoscopically impassable esophagitis. She reported to have consumed an unknown liquid from a small flask on a party three […]
Application of A(2)DS(2) score for predicting post-stroke pneumonia in elderly patients.
otolaryngologistsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.Alexandros,,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,tel : 00302841026182,00306932607174Πριν από 50 δευτερόλεπτα
Related Articles [Application of A(2)DS(2) score for predicting post-stroke pneumonia in elderly patients]. Nan Fang Yi Ke Da Xue Xue Bao. 2013 Nov;33(11):1615-9 Authors: Shang Y, Wang S, Bai X, Gao Z, Li J, Wu W Abstract OBJECTIVE: To investigate the risk factors for post-stroke pneumonia and assess the value of A(2)DS(2) score in predicting […]
Prevalence and characteristics of spontaneous tinnitus in 11-year-old children
10.3109/14992027.2015.1120890<br>Rachel Humphriss from #Audiology via ola Kala on Inoreader http://ift.tt/1SgR04S via IFTTT
Emerging technologies with potential for objectively evaluating speech recognition skills
10.3109/14992027.2015.1128570<br>Vishakha Waman Rawool from #Audiology via ola Kala on Inoreader http://ift.tt/1lNGPIc via IFTTT
More evidence emerges for ‘transmissible Alzheimer’s’ theory
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 1 ώρα
Autopsies reveal plaques in the brains of people who died after receiving grafts from cadavers. Nature News doi: 10.1038/nature.2016.19229 from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1SgPb8a via IFTTT
Resident Fatigue in Otolaryngology Residents: a Web Based Survey
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 1 ώρα
Publication date: Available online 25 January 2016 Source:American Journal of Otolaryngology Author(s): Andrew M. Nida, Benjamin J. Googe, Andrea F. Lewis, Warren L. May ImportanceResident fatigue has become a point of emphasis in medical education and its effects on otolaryngology residents and their patients requires further study.ObjectiveThe purpose of our study was to evaluate the […]
Ultrasonic Bone Aspirator Assisted Endoscopic Dacryocystorhinostomy
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 1 ώρα
Publication date: Available online 25 January 2016 Source:American Journal of Otolaryngology Author(s): Toby O. Steele, Machelle Wilson, E. Bradley Strong ObjectiveTo evaluate the ultrasonic bone aspirator versus traditional powered drill technique for use in endoscopic dacryocystorhinostomy.Study DesignRetrospective chart reviewSettingAcademic InstitutionSubjects and MethodsA retrospective chart review of all patients undergoing endoscopic dacryocystorhinostomy from June 2010 through […]
Ex Vivo Ovine Model for Head and Neck Surgical Simulation
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 1 ώρα
Publication date: Available online 25 January 2016 Source:American Journal of Otolaryngology Author(s): David C. Ianacone, Beverly J. Gnadt, Glenn Isaacson ObjectiveTo evaluate a fresh, ovine/sheep head and neck tissue model to teach Otolaryngology-Head and Neck surgical techniques.Study DesignObservational animal studySettingA university animal resource facilityMethodsTissue was collected from pre-pubescent sheep (n = 10; mean age: 4 […]
Long-term effect of in utero conditions on maternal survival later in life: evidence from Sub-Saharan Africa
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 1 ώρα
Abstract Sub-Saharan African countries have some of the world’s highest rates of maternal mortality. Most research on maternal mortality focuses on factors during pregnancy and delivery. However, consistent with the fetal programming hypothesis, a woman’s maternal survival may also be related to conditions she experienced while in utero. I examine this hypothesis in 14 African […]
Effects of geometric design of forest road and roadside vegetation on traffic noise reduction
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 1 ώρα
Abstract Geometric design of forest roads and design of their landscapes can reduce noise pollution and its harmful effects on human health. We investigated the effects of technical and biological parameters such as geometric road design and various roadside tree stands on reducing noise pollution according to the tree density and distance from roadway in […]
Biomass production, nutrient cycling and distribution in age-sequence Chinese fir ( Cunninghamia lanceolate ) plantations in subtropical China
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 1 ώρα
Abstract Biomass production and nutrient (N, P, K, Ca and Mg) accumulation, distribution and cycling were quantified in young, mature and over-mature (10-, 22-, and 34-year old) Chinese fir [Cunninghamia lanceolate (Lamb.) Hook] plantations in southern China. Total stand biomass of young, mature and over-mature stands was 38, 104 and 138 t ha−1 respectively. Biomass […]
Relational contracts for household formation, fertility choice and separation
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 1 ώρα
Abstract This paper applies the theory of relational contracts to a model in which a couple decides upon fertility and subsequently on continuation of the relationship. We formalize the idea that within-household-cooperation can be supported by selfinterest. Since the costs of raising children—a household public good—are unequally distributed between partners, a conflict between individually optimal […]
Comparative microsporogenesis and flower development in Eucalyptus urophylla × E. grandis
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 1 ώρα
Abstract Microsporogenesis and flower development in Eucalyptus urophylla × E. grandis were examined using chromosome tableting to provide a method to predict the meiotic stages in this species. Although microsporogenesis was normal, cytokinesis during meiosis of pollen mother cells occurred simultaneously, with strong asynchronism observed in the two different lengths of stamens in a flower […]
Estimation of gases emitted by forest fires based on remote sensing data
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 1 ώρα
Abstract Forest fire, an important agent for change in many forest ecosystems, plays an important role in atmospheric chemical cycles and the carbon cycle. The primary emissions from forest fire, CO2, CO, CH4, long-chained hydrocarbons and volatile organic oxides, however, have not been well quantified. Quantifying the carbonaceous gas emissions of forest fires is a […]
Diabetes and Periodontitis—A Dental Hygienist’s Perspective
Abstract Several decades of research of the interrelationships between diabetes and periodontitis have evolved into a significant body of knowledge that should be incorporated into dental practice. However, there may be a delay in implementing this important information into everyday patient care. Oral healthcare providers (i.e., dentists and dental hygienists) should be progressively engaged in changing the trajectory of the epidemics of diabetes and periodontitis. This article synthesizes the cumulative evidence on the diabetes-periodontitis link, proposes ideas for risk stratif... περισσότερα »
Emerging technologies with potential for objectively evaluating speech recognition skills.
*Emerging technologies with potential for objectively evaluating speech recognition skills.* Int J Audiol. 2016 Jan 25;:1-10 Authors: Rawool VW Abstract Work-related exposure to noise and other ototoxins can cause damage to the cochlea, synapses between the inner hair cells, a auditory nerve fibers, and higher auditory pathways, leading to difficulties in recognizing speech. Procedures designed to determine speech recognition scores (SRS) in an objective manner can be helpful in disability compensation cases where the worker claims to have poor speech perception due to exposure ...περισσότερα »
Prevalence and characteristics of spontaneous tinnitus in 11-year-old children.
*Prevalence and characteristics of spontaneous tinnitus in 11-year-old children.* Int J Audiol. 2016 Jan 25;:1-7 Authors: Humphriss R, Hall AJ, Baguley DM Abstract OBJECTIVE: To estimate the prevalence of spontaneous tinnitus in 11-year-old children. DESIGN: A prospective UK population-based study. STUDY SAMPLE: A total of 7092 children from the Avon longitudinal study of parents and children (ALSPAC) who attended the hearing session at age 11 years and answered questions about tinnitus. RESULTS: We estimated the prevalence of any spontaneous tinnitus as 28.1% (95% CI 27.1, 29.2%... περισσότερα »
Did ear sensory cell stereocilia evolve from gut microvilli?
Evolution likes to borrow. It can take an already-successful biological structure and alter it until it serves a new function. from #Audiology via ola Kala on Inoreader http://ift.tt/1nMwFcL via IFTTT
Needle-free injection of 5-aminolevulinic acid in photodynamic therapy for the treatment of non-melanoma skin cancer
ABSTRACT Background Photodynamic therapy (PDT) has been widely used in treatment for skin cancer. However, topical 5-aminolevulinic acid (ALA) in PDT demonstrates poor therapeutic effect due to its shallow penetration. And intralesional ALA-PDT can bring great pain. The purpose of this study was to evaluate the efficacy of PDT with needle-free injection of ALA in the treatment of nonmalignant skin tumors. Methods 54 non-melanocytic malignant lesions of 54 subjects were treated with needle-free injection of 20% 5-ALA under occlusion for 1.5 hours, and irradiated with light dose o... περισσότερα »
Hypertrophic lichen planus – successful treatment with acitretin
ABSTRACT Lichen planus classifies into different subtypes according to morphology and location. Hypertrophic LP (HLP) manifests a great challenge due to persistent itching, the risk to develop into squamous cell carcinoma and therapeutic resistance. We report two clinical cases exemplary for the successful treatment of dramatic-resistant HLP with acitretin. from #Dermatology via alexandrossfakianakis on Inoreader http://ift.tt/1RKzPKs via IFTTT
BCG vaccine for immunotherapy in warts: is it really safe in a tuberculosis endemic area?
ABSTRACT Management of recurrent and or recalcitrant warts can be a therapeutic challenge and in such cases invoking body's own immunity may help to overcome the present episode and also prevent recurrences. Bacilli Calmette Geurin (BCG) immunotherapy has long been considered to be an effective and safe modality in such cases. We present a series of seven cases treated with BCG immunotherapy wherein a single dose of BCG caused regression of wart in 85.7% patients and complete resolution was evident in 28.6% patients. However, the development of adverse effects precluded any further...περισσότερα »
Recalcitrant molluscum contagiosum successfully treated with sinecatechins
from #Dermatology via alexandrossfakianakis on Inoreader http://ift.tt/1OV463m via IFTTT
Coral snake bites (Micrurus spp.) in Brazil: a review of literature reports.
otolaryngologistsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.Alexandros,,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,tel : 00302841026182,00306932607174Πριν από 1 ώρα
Coral snake bites (Micrurus spp.) in Brazil: a review of literature reports. Clin Toxicol (Phila). 2016 Jan 25;:1-13 Authors: Bucaretchi F, De Capitani EM, Vieira RJ, Rodrigues CK, Zannin M, Da Silva NJ, Casais-E-Silva LL, Hyslop S Abstract CONTEXT: In the Americas, the main representatives of the family Elapidae are coral snakes of the genus […]
Long-term symptomatic control of Zenker diverticulum by flexible endoscopic mucomyotomy with the hook knife and predisposing factors for clinical recurrence.
otolaryngologistsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.Alexandros,,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,tel : 00302841026182,00306932607174Πριν από 1 ώρα
Long-term symptomatic control of Zenker diverticulum by flexible endoscopic mucomyotomy with the hook knife and predisposing factors for clinical recurrence. Scand J Gastroenterol. 2016 Jan 25;:1-6 Authors: Brueckner J, Schneider A, Messmann H, Gölder SK Abstract Objective Flexible endoscopic treatment for Zenker diverticulum (ZD) is well established. Although recurrence of symptoms is relatively frequent, it […]
Novel methods of drug administration for the treatment and care of older patients.
otolaryngologistsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.Alexandros,,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,tel : 00302841026182,00306932607174Πριν από 1 ώρα
Novel methods of drug administration for the treatment and care of older patients. Int J Pharm. 2016 Jan 22; Authors: Quinn HL, Hughes CM, Donnelly RF Abstract The number of older people globally is increasing, contributing to a growing burden of morbidity and mortality. With this shift in population demographic, comes a new challenge in […]
Long-term results after laparoscopic sleeve gastrectomy in a large monocentric series.
otolaryngologistsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.Alexandros,,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,tel : 00302841026182,00306932607174Πριν από 1 ώρα
Long-term results after laparoscopic sleeve gastrectomy in a large monocentric series. Surg Obes Relat Dis. 2015 Oct 1; Authors: Casella G, Soricelli E, Giannotti D, Collalti M, Maselli R, Genco A, Redler A, Basso N Abstract BACKGROUND: Laparoscopic sleeve gastrectomy (SG) has gained great popularity as a stand-alone bariatric procedure because short- and mid-term outcomes […]
Laparoscopic Gastrostomy for a Patient with Wernicke’s Encephalopathy after Gastrectomy-A Case Report with a Literature Review.
otolaryngologistsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.Alexandros,,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,tel : 00302841026182,00306932607174Πριν από 1 ώρα
[Laparoscopic Gastrostomy for a Patient with Wernicke’s Encephalopathy after Gastrectomy-A Case Report with a Literature Review]. Gan To Kagaku Ryoho. 2015 Nov;42(12):2037-9 Authors: Arita T, Komatsu S, Kosuga T, Konishi H, Morimura R, Murayama Y, Kuriu Y, Shiozaki A, Ikoma H, Nakanishi M, Ichikawa D, Okamoto K, Otsuji E Abstract Wernicke’s encephalopathy is usually related […]
Clinical Significance of Placing a PEG during Chemoradiotherapy for Advanced Esophageal Cancer.
otolaryngologistsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.Alexandros,,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,tel : 00302841026182,00306932607174Πριν από 1 ώρα
[Clinical Significance of Placing a PEG during Chemoradiotherapy for Advanced Esophageal Cancer]. Gan To Kagaku Ryoho. 2015 Nov;42(12):1929-31 Authors: Matsuyama J, Yamamoto Y, Yamato H, Takeda M, Hashimoto Y, Shirakawa M, Tokuoka M, Ide Y, Yokoyama S, Fukushima Y, Kodama K, Sasaki Y Abstract BACKGROUND: Unresectable advanced esophageal cancer is often treated with chemotherapy or […]
A Case of Advanced Esophageal Cancer Patient with Schizophrenia Successfully Treated with Chemoradiation Therapy with S-1 and CDDP.
otolaryngologistsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.Alexandros,,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,tel : 00302841026182,00306932607174Πριν από 1 ώρα
[A Case of Advanced Esophageal Cancer Patient with Schizophrenia Successfully Treated with Chemoradiation Therapy with S-1 and CDDP]. Gan To Kagaku Ryoho. 2015 Nov;42(12):1923-5 Authors: Tsuruda Y, Okumura H, Uchikado Y, Megumi K, Urata M, Kawagoe K, Satake S, Kita Y, Uenosono Y, Arigami T, Mori S, Baba K, Ishigami S, Owaki T, Natsugoe S […]
A Case of Esophageal Cancer Complicated with Idiopathic Thrombocytopenic Purpura.
otolaryngologistsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.Alexandros,,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,tel : 00302841026182,00306932607174Πριν από 1 ώρα
[A Case of Esophageal Cancer Complicated with Idiopathic Thrombocytopenic Purpura]. Gan To Kagaku Ryoho. 2015 Nov;42(12):1911-3 Authors: Nakahara Y, Yamasaki M, Makino T, Miyazaki Y, Takahashi T, Kurokawa Y, Nakajima K, Takiguchi S, Mori M, Doki Y Abstract The patient was a 58-year-old woman. She was diagnosed with idiopathic thrombocytopenic purpura(ITP)when she was 41 years […]
Effects of Device-Facilitated Isometric Progressive Resistance Oropharyngeal Therapy on Swallowing and Health-Related Outcomes in Older Adults with Dysphagia.
otolaryngologistsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.Alexandros,,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,tel : 00302841026182,00306932607174Πριν από 1 ώρα
Effects of Device-Facilitated Isometric Progressive Resistance Oropharyngeal Therapy on Swallowing and Health-Related Outcomes in Older Adults with Dysphagia. J Am Geriatr Soc. 2016 Jan 25; Authors: Rogus-Pulia N, Rusche N, Hind JA, Zielinski J, Gangnon R, Safdar N, Robbins J Abstract Swallowing disorders (dysphagia) are associated with malnutrition, aspiration pneumonia, and mortality in older adults. […]
Botulinum toxin-A injections vs radiotherapy for drooling in ALS.
otolaryngologistsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.Alexandros,,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,tel : 00302841026182,00306932607174Πριν από 1 ώρα
Botulinum toxin-A injections vs radiotherapy for drooling in ALS. Acta Neurol Scand. 2016 Jan 25; Authors: Weikamp JG, Schinagl DA, Verstappen CC, Schelhaas HJ, de Swart BJ, Kalf JG Abstract OBJECTIVES: Botulinum neurotoxin (BoNT) injections in the salivary glands and radiotherapy (RT) on these glands are commonly used to alleviate severe drooling in patients with […]
Controlled release of a microencapsulated arduous semi-hydrophobic active from coatings: Superhydrophilic polyelectrolyte shells as globally rate-determining barriers
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 1 ώρα
Publication date: 10 March 2016 Source:Journal of Controlled Release, Volume 225 Author(s): Jonatan Bergek, Markus Andersson Trojer, Hermann Uhr, Lars Nordstierna Polymethylmethacrylate-based microcapsules containing the antimicrobial agent 2-n-octyl-4-isothiazolin-3-one (OIT) decorated by an anchored polyelectrolyte brush consisting of an amphiphilic diblock copolymer of polymethylmethacrylate-block-poly(sodium methacrylate) type have been formulated via a coacervation technique. The polyelectrolyte brush […]
Formulations for microprojection/microneedle vaccine delivery: Structure, strength and release profiles
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 1 ώρα
Publication date: 10 March 2016 Source:Journal of Controlled Release, Volume 225 Author(s): Anthony P. Raphael, Michael L. Crichton, Robert J. Falconer, Stefano Meliga, Xianfeng Chen, Germain J.P. Fernando, Han Huang, Mark A.F. Kendall To develop novel methods for vaccine delivery, the skin is viewed as a high potential target, due to the abundance of immune […]
Exploring the use of nanocarrier systems to deliver the magical molecule; Curcumin and its derivatives
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 1 ώρα
Publication date: 10 March 2016 Source:Journal of Controlled Release, Volume 225 Author(s): Mina Mehanny, Rania M. Hathout, Ahmed S. Geneidi, Samar Mansour Curcumin and its derivatives; curcuminoids have been proven as potential remedies in different diseases. However, their delivery carries several challenges owing to their poor aqueous solubility, photodegradation, chemical instability, poor bioavailability and rapid […]
pH gradient difference around ischemic brain tissue can serve as a trigger for delivering polyethylene glycol-conjugated urokinase nanogels
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 1 ώρα
Publication date: 10 March 2016 Source:Journal of Controlled Release, Volume 225 Author(s): Wei Cui, Ran Liu, Haiqiang Jin, Pu Lv, Yuyao Sun, Xi Men, Saina Yang, Xiaozhong Qu, Zhenzhong Yang, Yining Huang Background and PurposepH-sensitive polyethylene glycol-conjugated urokinase nanogels (PEG-UKs) were previously reported to be a new form of UK nanogels that could release UK […]
The Case of a Zebra That Was Misdiagnosed as a Horse: Pulmonary Tumor Thrombotic Microangiopathy, a New Paraneoplastic Syndrome, Mimicking PD-1-Induced Pneumonitis
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 1 ώρα
A case report of a 47-year-old woman with triple-negative breast cancer on a clinical trial called PRIMETIME (NCT02518958) who received the anti-PD-1 inhibitor nivolumab and the experimental anticancer agent RRx-001 is presented. Although initially diagnosed and treated for anti-PD-1-induced pneumonitis, clinical and radiological abnormalities triggered further investigation, leading to the diagnosis of pulmonary tumor thrombotic […]
Simeprevir plus sofosbuvir (12 and 8 Weeks) in HCV genotype 1-infected patients without cirrhosis: OPTIMIST-1, a phase 3, randomized study
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 1 ώρα
Hepatology from #Medicine via ola Kala on Inoreader http://ift.tt/1nkWFv5 Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174 from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1K808rh via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1Nxje50 via IFTTT
The M2 phenotype of tumor-associated macrophages in the stroma confers a poor prognosis in pancreatic cancer
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 1 ώρα
Tumor Biology from #Medicine via ola Kala on Inoreader http://ift.tt/200SLcs Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174 from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1Uo2aEm via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1K80wpR via IFTTT
Assessing cerebrovascular autoregulation in infants with necrotizing enterocolitis using near-infrared spectroscopy
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 1 ώρα
Pediatric Research from #Medicine via ola Kala on Inoreader http://ift.tt/200SKVY Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174 from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1Uo2aEi via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1NxjcKs via IFTTT
Coffee consumption and the risk of cirrhosis
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 1 ώρα
Alimentary Pharmacology and Therapeutics from #Medicine via ola Kala on Inoreader http://ift.tt/1nkWFeB Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174 from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1K808aZ via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1K80yxY via IFTTT
Long-term safety of a coordinated delivery tablet of enteric-coated aspirin 325 mg and immediate-release omeprazole 40 mg for secondary cardiovascular disease prevention in patients at gi risk
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 1 ώρα
Cardiovascular Therapeutics from #Medicine via ola Kala on Inoreader http://ift.tt/1nkWEaG Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174 from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1K8062F via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1NxjcKm via IFTTT
Dynamically adjustable foot-ground contact model to estimate ground reaction force during walking and running
Publication date: March 2016 *Source:*Gait & Posture, Volume 45 Author(s): Yihwan Jung, Moonki Jung, Jiseon Ryu, Sukhoon Yoon, Sang-Kyoon Park, Seungbum Koo Human dynamic models have been used to estimate joint kinetics during various activities. Kinetics estimation is in demand in sports and clinical applications where data on external forces, such as the ground reaction force (GRF), are not available. The purpose of this study was to estimate the GRF during gait by utilizing distance- and velocity-dependent force models between the foot and ground in an inverse-dynamics-based optim...περισσότερα »
Dynamically adjustable foot-ground contact model to estimate ground reaction force during walking and running
Publication date: March 2016 *Source:*Gait & Posture, Volume 45 Author(s): Yihwan Jung, Moonki Jung, Jiseon Ryu, Sukhoon Yoon, Sang-Kyoon Park, Seungbum Koo Human dynamic models have been used to estimate joint kinetics during various activities. Kinetics estimation is in demand in sports and clinical applications where data on external forces, such as the ground reaction force (GRF), are not available. The purpose of this study was to estimate the GRF during gait by utilizing distance- and velocity-dependent force models between the foot and ground in an inverse-dynamics-based optim...περισσότερα »
Dynamically adjustable foot-ground contact model to estimate ground reaction force during walking and running
Publication date: March 2016 *Source:*Gait & Posture, Volume 45 Author(s): Yihwan Jung, Moonki Jung, Jiseon Ryu, Sukhoon Yoon, Sang-Kyoon Park, Seungbum Koo Human dynamic models have been used to estimate joint kinetics during various activities. Kinetics estimation is in demand in sports and clinical applications where data on external forces, such as the ground reaction force (GRF), are not available. The purpose of this study was to estimate the GRF during gait by utilizing distance- and velocity-dependent force models between the foot and ground in an inverse-dynamics-based optim...περισσότερα »
Gold nanoparticles as sensitive optical probes
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 2 ώρες
Analyst, 2016, Accepted Manuscript DOI: 10.1039/C5AN02651B, Tutorial Review Zhiqin Yuan, Cho-Chun Hu, Huan-Tsung Chang, Chao Lu Gold nanoparticles (Au NPs) have become one of the most popular materials for sensing of analytes of interest in the last decade, mainly because of their ease in preparation and… The content of this RSS Feed (c) The Royal […]
The Vibrational Spectroscopy of Metal Carbonyls for Bio-Imaging and -Sensing
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 2 ώρες
Analyst, 2016, Accepted Manuscript DOI: 10.1039/C5AN02191J, Critical Review Zhiyong Lam, Kien Voon Kong, Malini Olivo, Weng Kee Leong This review covers how the vibrational spectroscopy of transition metal carbonyls have been used in biological and biomedical applications. The vibrational spectra of these complexes, which have traditionally been viewed… The content of this RSS Feed (c) […]
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