Αρχειοθήκη ιστολογίου

Αλέξανδρος Γ. Σφακιανάκης
ΩτοΡινοΛαρυγγολόγος
Αναπαύσεως 5
Άγιος Νικόλαος Κρήτη 72100
2841026182
6032607174

Κυριακή 14 Φεβρουαρίου 2016

OtoRhinoLaryngology & Medicine,New Articles,February 14th,2016,Love & Wisdom,EQUANIMITY (Upeksha),JOY (Mudita),COMPASSION (Karuna),LOVE (Maitri/Metta)


Competitive binding of anticancer drugs 5-fluorouracil and cyclophosphamide with serum albumin: Calorimetric insights

Publication date: Available online 6 February 2016 Source:Biochimica et Biophysica Acta (BBA) – General Subjects Author(s): Anu A. Thoppil, Sinjan Choudhary, Nand Kishore BackgroundIsothermal titration calorimetry (ITC) has emerged as an excellent method to characterize drug–protein interactions. 5-Fluorouracil and cyclophosphamide have been used in combination for the treatment of breast carcinoma, though individually these drugs […]

Le news più importanti della settimana – Hardware upgrade.it

Hardware upgrade.it Le news più importanti della settimana Hardware upgrade.it In breve ecco le notizie più importanti della settimana, corredate da un link di approfondimento. Non perdetevi inoltre i suggerimenti per la lettura dei nostri articoli, sfruttando il tempo concesso dal weekend per approfondire con calma alcuni temi … from #ORL-AlexandrosSfakianakis via simeraentaxei on Inoreader […]

Team limber up for Cancer Centre Campaign – Gazette

Gazette Team limber up for Cancer Centre Campaign Gazette “Through all the hardship, chemotherapy, radiotherapy, having to be feed through a tube and many, many hospital appointments, he came out at the end having kicked cancer. “We want to raise as much money as we can for the cancer centre at Colchester … from #ORL-AlexandrosSfakianakis […]

Vil sette legers verdier i spill

Som leder for Skottlands allmennleger vil Miles Mack sikre tjenestene via bevisstgjort indre motivasjon snarere enn gamle, ytre reguleringer. from #ORL-AlexandrosSfakianakis via simeraentaxei on Inoreader http://ift.tt/1KioFdO via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1Spy9pS via IFTTT

Protective effects of retinoid x receptors on retina pigment epithelium cells

Publication date: Available online 13 February 2016 Source:Biochimica et Biophysica Acta (BBA) – Molecular Cell Research Author(s): VictoriaBelén Ayala-Peña, Fiorella Pilotti, Yanel Volonté, Nora P. Rotstein, Luis E. Politi, Olga Lorena German Age-related macular degeneration (AMD) is among the main pathologies leading to blindness in adults and has currently no cure or effective treatment. Selective […]

IJMS, Vol. 17, Pages 36: Drosophotoxicology: An Emerging Research Area for Assessing Nanoparticles Interaction with Living Organisms

The rapid development of nanotechnology allowed the fabrication of a wide range of different nanomaterials, raising many questions about their safety and potential risks for the human health and environment. Most of the current nanotoxicology research is not standardized, hampering any comparison or reproducibility of the obtained results. Drosophotoxicology encompasses the plethora of methodological approaches […]

The Subjective Sensation of Synchrony: An Experimental Study

The Subjective Sensation of Synchrony: An Experimental Study: by Joan Llobera, Caecilia Charbonnier, Sylvain Chagué, Delphine Preissmann, Jean-Philippe Antonietti, François Ansermet, Pierre J. Magistretti People performing actions together have a natural tendency to synchronize their behavior. Consistently, people doing a task together build internal representations not only of their actions and goals, but also of […]

Ultrasound Strain Elastography in Assessment of Muscle Stiffness in Acute Levodopa Challenge Test: A Feasibility Study

Publication date: Available online 13 February 2016 Source:Ultrasound in Medicine & Biology Author(s): Jing Gao, Li-Juan Du, Wen He, Shuo Li, Ling-Gang Cheng To evaluate the feasibility of ultrasound strain elastography in assessing the response of muscle stiffness to the acute levodopa test, we prospectively performed strain elastography on the biceps brachii muscle (BBM) of […]

Serogroup A Meningococcal Infection

A Seroepidemiological Study of Serogroup A Meningococcal Infection in the African Meningitis Belt: by Olivier Manigart, Caroline Trotter, Helen Findlow, Abraham Assefa, Wude Mihret, Tesfaye Moti Demisse, Biruk Yeshitela, Isaac Osei, Abraham Hodgson, Stephen Laryea Quaye, Samba Sow, Mamadou Coulibaly, Kanny Diallo, Awa Traore, Jean-Marc Collard, Rahamatou Moustapha Boukary, Oumarou Djermakoye, Ali Elhaji Mahamane, Jean-François […]

KSHV-TK is a tyrosine kinase that disrupts focal adhesions and induces Rho-mediated cell contraction

The EMBO Journal from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1mAeZQi via IFTTT

Family quality of life among families with a child who has a severe neurodevelopmental disability: Impact of family and child socio-demographic factors.

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 12 δευτερόλεπτα
Family quality of life among families with a child who has a severe neurodevelopmental disability: Impact of family and child socio-demographic factors Res Dev Disabil. 2016 Feb 9;53-54:95-106 Authors: Schertz M, Karni-Visel Y, Tamir A, Genizi J, Roth D Abstract We aimed to examine family quality of life (FQOL) of Northern Israeli families having a child with a severe neurodevelopmental disability and its relation to socio-demographics. The cohort included caregivers of 70 children ages (mean±standard deviation) 5.36±3.53 years. Families were two-parent (85.7%), lived in the perip... περισσότερα »

Response of the human tympanic membrane to transient acoustic and mechanical stimuli

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 13 δευτερόλεπτα
Response of the human tympanic membrane to transient acoustic and mechanical stimuli via Hearing Research Publication date: Available online 12 February 2016 *Source:*Hearing Research Author(s): Payam Razavi, Michael E. Ravicz, Ivo Dobrev, Jeffrey Tao Cheng, Cosme Furlong, John J. Rosowski The response of the tympanic membrane (TM) to transient environmental sounds and the contributions of different parts of the TM to middle-ear sound transmission were investigated by measuring the TM response to global transients (acoustic clicks) and to local transients (mechanical impulses) applied... περισσότερα »

Masking Release in Children and Adults With Hearing Loss When Using Amplification

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 13 δευτερόλεπτα
Masking Release in Children and Adults With Hearing Loss When Using Amplification: Purpose This study compared masking release for adults and children with normal hearing and hearing loss. For the participants with hearing loss, masking release using simulated hearing aid amplification with 2 different compression speeds (slow, fast) was compared. Method Sentence recognition in unmodulated noise was compared with recognition in modulated noise (masking release). Recognition was measured for participants with hearing loss using individualized amplification via the hearing-aid simu... περισσότερα »

Effects of Removing Low-Frequency Electric Information on Speech Perception With Bimodal Hearing

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 13 δευτερόλεπτα
Effects of Removing Low-Frequency Electric Information on Speech Perception With Bimodal Hearing: Purpose The objective was to determine whether speech perception could be improved for bimodal listeners (those using a cochlear implant [CI] in one ear and hearing aid in the contralateral ear) by removing low-frequency information provided by the CI, thereby reducing acoustic–electric overlap. Method Subjects were adult CI subjects with at least 1 year of CI experience. Nine subjects were evaluated in the CI-only condition (control condition), and 26 subjects were evaluated in the b... περισσότερα »

High Fat Diet Induced Inflammation

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 15 δευτερόλεπτα
Fibroblast Growth Factor 21 (FGF21) Protects against High Fat Diet Induced Inflammation and Islet Hyperplasia in Pancreas: [image: journal.pone.0148252.g001] by Garima Singhal, ffolliott Martin Fisher, Melissa J. Chee, Tze Guan Tan, Abdelfattah El Ouaamari, Andrew C. Adams, Robert Najarian, Rohit N. Kulkarni, Christophe Benoist, Jeffrey S. Flier, Eleftheria Maratos-Flier Fibroblast growth factor 21 (FGF21) is an important endocrine metabolic regulator expressed in multiple tissues including liver and adipose tissue. Although highest levels of expression are in pancreas, little i... περισσότερα »

Competitive binding of anticancer drugs 5-fluorouracil and cyclophosphamide with serum albumin: Calorimetric insights

orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 15 δευτερόλεπτα
Publication date: Available online 6 February 2016 Source:Biochimica et Biophysica Acta (BBA) – General Subjects Author(s): Anu A. Thoppil, Sinjan Choudhary, Nand Kishore BackgroundIsothermal titration calorimetry (ITC) has emerged as an excellent method to characterize drug–protein interactions. 5-Fluorouracil and cyclophosphamide have been used in combination for the treatment of breast carcinoma, though individually these drugs… Continue reading Competitive binding of anticancer drugs 5-fluorouracil and cyclophosphamide with serum albumin: Calorimetric insights

Is there too much stress on stress? – The Guardian

orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 15 δευτερόλεπτα
The Guardian Is there too much stress on stress? The Guardian Most had fever (sometimes with mental confusion), an enlarged spleen or liver, inflamed tonsils, a skin rash and so forth…”. Moreover …. Cooper wrote a book examining the links between such emotional stress and cancer (links that are debatable … from #ORL-AlexandrosSfakianakis via simeraentaxei… Continue reading Is there too much stress on stress? – The Guardian

Team limber up for Cancer Centre Campaign – Gazette

orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 15 δευτερόλεπτα
Gazette Team limber up for Cancer Centre Campaign Gazette «Through all the hardship, chemotherapy, radiotherapy, having to be feed through a tube and many, many hospital appointments, he came out at the end having kicked cancer. «We want to raise as much money as we can for the cancer centre at Colchester … from #ORL-AlexandrosSfakianakis… Continue reading Team limber up for Cancer Centre Campaign – Gazette

Vil sette legers verdier i spill

orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 15 δευτερόλεπτα
Som leder for Skottlands allmennleger vil Miles Mack sikre tjenestene via bevisstgjort indre motivasjon snarere enn gamle, ytre reguleringer. from #ORL-AlexandrosSfakianakis via simeraentaxei on Inoreader http://ift.tt/1KioFdO via IFTTT

Le news più importanti della settimana – Hardware upgrade.it

orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 15 δευτερόλεπτα
Hardware upgrade.it Le news più importanti della settimana Hardware upgrade.it In breve ecco le notizie più importanti della settimana, corredate da un link di approfondimento. Non perdetevi inoltre i suggerimenti per la lettura dei nostri articoli, sfruttando il tempo concesso dal weekend per approfondire con calma alcuni temi … from #ORL-AlexandrosSfakianakis via simeraentaxei on Inoreader… Continue reading Le news più importanti della settimana – Hardware upgrade.it

Protective effects of retinoid x receptors on retina pigment epithelium cells

orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 18 δευτερόλεπτα
Publication date: Available online 13 February 2016 Source:Biochimica et Biophysica Acta (BBA) – Molecular Cell Research Author(s): VictoriaBelén Ayala-Peña, Fiorella Pilotti, Yanel Volonté, Nora P. Rotstein, Luis E. Politi, Olga Lorena German Age-related macular degeneration (AMD) is among the main pathologies leading to blindness in adults and has currently no cure or effective treatment. Selective… Continue reading Protective effects of retinoid x receptors on retina pigment epithelium cells

IJMS, Vol. 17, Pages 36: Drosophotoxicology: An Emerging Research Area for Assessing Nanoparticles Interaction with Living Organisms

orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 18 δευτερόλεπτα
The rapid development of nanotechnology allowed the fabrication of a wide range of different nanomaterials, raising many questions about their safety and potential risks for the human health and environment. Most of the current nanotoxicology research is not standardized, hampering any comparison or reproducibility of the obtained results. Drosophotoxicology encompasses the plethora of methodological approaches… Continue reading IJMS, Vol. 17, Pages 36: Drosophotoxicology: An Emerging Research Area for Assessing Nanoparticles Interaction with Living Organisms

The Subjective Sensation of Synchrony: An Experimental Study

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 19 δευτερόλεπτα
The Subjective Sensation of Synchrony: An Experimental Study: [image: journal.pone.0147008.g001] by Joan Llobera, Caecilia Charbonnier, Sylvain Chagué, Delphine Preissmann, Jean-Philippe Antonietti, François Ansermet, Pierre J. Magistretti People performing actions together have a natural tendency to synchronize their behavior. Consistently, people doing a task together build internal representations not only of their actions and goals, but also of the other people performing the task. However, little is known about which are the behavioral mechanisms and the psychological facto... περισσότερα »

Serogroup A Meningococcal Infection

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 19 δευτερόλεπτα
A Seroepidemiological Study of Serogroup A Meningococcal Infection in the African Meningitis Belt: [image: journal.pone.0147928.t001] by Olivier Manigart, Caroline Trotter, Helen Findlow, Abraham Assefa, Wude Mihret, Tesfaye Moti Demisse, Biruk Yeshitela, Isaac Osei, Abraham Hodgson, Stephen Laryea Quaye, Samba Sow, Mamadou Coulibaly, Kanny Diallo, Awa Traore, Jean-Marc Collard, Rahamatou Moustapha Boukary, Oumarou Djermakoye, Ali Elhaji Mahamane, Jean-François Jusot, Cheikh Sokhna, Serge Alavo, Souleymane Doucoure, El Hadj Ba, Mariétou Dieng, Aldiouma Diallo, Doumagoum Moto Da... περισσότερα »

Molecular Markers for Indeterminate Thyroid Nodules : Afirma GEC molecular test,ThyroSeq v.2 molecular test

Αλέξανδρος ΣφακιανάκηςστοMedicine by Sfakianakis G. AlexandrosΠριν από 20 δευτερόλεπτα
Randomized Trial Comparing Performance of Molecular Markers for Indeterminate Thyroid Nodules: *Condition*: Thyroid *Interventions*: Other: Afirma GEC; Other: ThyroSeq v.2 *Sponsor*: Jonsson Comprehensive Cancer Center Groups/CohortsAssigned Interventions Afirma GEC single molecular test GEC of collected tissue Other: Afirma GEC Afirma GEC molecular test on collected thyroid tissue ThyroSeq v.2 single molecular test ThyroSeq v.2 of collected tissue Other: ThyroSeq v.2 ThyroSeq v.2 molecular test on collected thyroid tissue Detailed Description: 1. All patients undergo... περισσότερα »

Research Tissue Biobanks

Αλέξανδρος ΣφακιανάκηςστοMedicine by Sfakianakis G. AlexandrosΠριν από 20 δευτερόλεπτα
Challenges for quality management in implementation, maintenance, and sustainability of research tissue biobanks: AbstractAvailability of high-quality human tissue samples and access to associated histopathological and clinical data is essential for basic and translational biomedical research, especially in areas of personalized medicine, drug, and biomarker development and mechanistically oriented biomedical research projects. Therefore, it is pivotal to establish and maintain quality-assured tissue biobanks that provide high-quality biomaterial to research thereby increasing the i... περισσότερα »

Famciclovir may be the antiviral agent of choice in the treatment of patients with severe facial palsy

Αλέξανδρος ΣφακιανάκηςστοMedicine by Sfakianakis G. AlexandrosΠριν από 20 δευτερόλεπτα
*Comparison of acyclovir and famciclovir for the treatment of Bell’s palsy:* Abstract*The relative effectiveness of acyclovir and famciclovir in the treatment of Bell’s palsy is unclear. This study therefore compared recovery outcomes in patients with Bell’s palsy treated with acyclovir and famciclovir. The study cohort consisted of patients with facial palsy who visited the outpatient clinic between January 2006 and January 2014. Patients were treated with prednisolone plus either acyclovir (n = 457) or famciclovir (n = 245). Patient outcomes were measured using the House-Brackmann... περισσότερα »

Acyclovir and famciclovir for the treatment of Bell’s palsy : Treatment with steroid plus famciclovir was more effective than treatment with steroid plus acyclovir in patients with severe facial palsy. Famciclovir may be the antiviral agent of choice in the treatment of patients with severe facial palsy.

Αλέξανδρος ΣφακιανάκηςστοMedicine by Sfakianakis G. AlexandrosΠριν από 20 δευτερόλεπτα
Comparison of acyclovir and famciclovir for the treatment of Bell’s palsy: AbstractThe relative effectiveness of acyclovir and famciclovir in the treatment of Bell’s palsy is unclear. This study therefore compared recovery outcomes in patients with Bell’s palsy treated with acyclovir and famciclovir. The study cohort consisted of patients with facial palsy who visited the outpatient clinic between January 2006 and January 2014. Patients were treated with prednisolone plus either acyclovir (*n* = 457) or famciclovir (*n* = 245). Patient outcomes were measured using the House-Brackman... περισσότερα »

Stationary facial nerve paresis after surgery for recurrent parotid pleomorphic adenoma

Αλέξανδρος ΣφακιανάκηςστοMedicine by Sfakianakis G. AlexandrosΠριν από 20 δευτερόλεπτα
Stationary facial nerve paresis after surgery for recurrent parotid pleomorphic adenoma: a follow-up study of 219 cases in Denmark in the period 1985–2012: AbstractThe purpose was to assess degree of permanent facial nerve dysfunction after surgery for recurrent pleomorphic adenoma (RPA) of the parotid gland, including variables that might influence re-operation outcomes. Nationwide retrospective longitudinal cohort study including a questionnaire survey of patients undergoing surgery for RPA. Of 219 living patients, 198 (92 %) responded and 127 (63 %) reported no facial dysfunctio... περισσότερα »

Balloon dilation of the eustachian tube

Αλέξανδρος ΣφακιανάκηςστοMedicine by Sfakianakis G. AlexandrosΠριν από 20 δευτερόλεπτα
: a tympanometric outcomes analysis via Latest Results for Journal of Otolaryngology - Head & Neck Surgery AbstractBackgroundEustachian tube dysfunction (ETD) is a common medical issue, occurring in at least 1 % of the adult population. Patients suffering from ET dysfunction typically present with complaints of hearing loss or sensation of pressure or plugged ear, which can lead to impaired quality of life. Over time ETD can result in conductive hearing loss or choleastatoma formation. Effective theraputic options for ET dysfunction are few. Eustachian tube balloon dilation is a novel... περισσότερα »

Bone invasion in small-sized (4cm or less) oral squamous cell carcinoma

Αλέξανδρος ΣφακιανάκηςστοMedicine by Sfakianakis G. AlexandrosΠριν από 20 δευτερόλεπτα
Staging significance of bone invasion in small-sized (4cm or less) oral squamous cell carcinoma as defined by the American Joint Committee on Cancer via ScienceDirect Publication: Oral Oncology Publication date: Available online 12 February 2016 *Source:*Oral Oncology Author(s): Su Kyung Kuk, Hye Jung Yoon, Seong Doo Hong, Sam Pyo Hong, Jae Il Lee ObjectivesThe staging significance of bone invasion is controversial in oral squamous cell carcinoma (OSCC) cases with tumors measuring 4cm or less according to the American Joint Committee on Cancer (AJCC). Our aim was to retrospectively exa... περισσότερα »

IJMS, Vol. 17, Pages 36: Drosophotoxicology: An Emerging Research Area for Assessing Nanoparticles Interaction with Living Organisms

Αλέξανδρος ΣφακιανάκηςστοMedicine by Sfakianakis G. AlexandrosΠριν από 20 δευτερόλεπτα
The rapid development of nanotechnology allowed the fabrication of a wide range of different nanomaterials, raising many questions about their safety and potential risks for the human health and environment. Most of the current nanotoxicology research is not standardized, hampering any comparison or reproducibility of the obtained results. Drosophotoxicology encompasses the plethora of methodological approaches addressing the use of Drosophila melanogaster as a choice organism in toxicology studies. Drosophila melanogaster model offers several important advantages, such as a relat... περισσότερα »

Dihydrotestosterone on the Development of Graves' Disease in Female

Αλέξανδρος ΣφακιανάκηςστοMedicine by Sfakianakis G. AlexandrosΠριν από 20 δευτερόλεπτα
The Influence of Dihydrotestosterone on the Development of Graves' Disease in Female BALB/c Mice: Thyroid , Vol. 0, No. 0. Author information Lianye Liu,1,2,* Liping Wu,1,* Aibo Gao,1 Qi Zhang,1 Hongjun Lv,1 Li Xu,1 Chuanqing Xie,1 Qian Wu,3Peng Hou,1 and Bingyin Shi1 1Department of Endocrinology, The First Affiliated Hospital of Xi'an Jiaotong University Health Science Center, Xi'an, China. 2Department of Nephrology and Endocrinology, Weinan Central Hospital, Weinan, China. 3Department of Epidemiology and Biostatistics, School of Public Heath, Xi'an Jiaotong University Health Scien... περισσότερα »

Pulmonary Metastases Arising from Follicular Cell–Derived Thyroid Cancer

Αλέξανδρος ΣφακιανάκηςστοMedicine by Sfakianakis G. AlexandrosΠριν από 20 δευτερόλεπτα
Time Course and Predictors of Structural Disease Progression in Pulmonary Metastases Arising from Follicular Cell–Derived Thyroid Cancer: Thyroid , Vol. 0, No. 0. Author information Mona M. Sabra,1 Ronald Ghossein,2 and R. Michael Tuttle1 1Endocrinology Service, Department of Medicine, Memorial Sloan-Kettering Cancer Center and Weill-Cornell College of Medicine, New York, New York. 2Department of Pathology, Memorial Sloan-Kettering Cancer Center and Weill-Cornell College of Medicine, New York, New York. Address correspondence to: *Mona M. Sabra, MD* *Memorial Sloan-Kettering Cancer C... περισσότερα »

Acute Otitis Media Infection caused by Haemophilus influenzae

Αλέξανδρος ΣφακιανάκηςστοMedicine by Sfakianakis G. AlexandrosΠριν από 20 δευτερόλεπτα
Serum Cytokine Biomarkers Accurately Predict Presence of Acute Otitis Media Infection and Recovery caused by Haemophilus influenzae via International Journal of Pediatric Otorhinolaryngology Publication date: Available online 12 February 2016 *Source:*International Journal of Pediatric Otorhinolaryngology Author(s): Michael E. Pichichero, Anthony Almudevar ObjectiveWe sought to develop an optimal model using a combination of serum biomarker pro-inflammatory and dampening inflammatory cytokine proteins to predict the presence of acute otitis media (AOM) infection and recovery caused by N... περισσότερα »

Chloral Hydrate Sedation for Auditory Brainstem Response (ABR) Testing in Children

Αλέξανδρος ΣφακιανάκηςστοMedicine by Sfakianakis G. AlexandrosΠριν από 20 δευτερόλεπτα
: Safety and Effectiveness via International Journal of Pediatric Otorhinolaryngology Publication date: Available online 13 February 2016 *Source:*International Journal of Pediatric Otorhinolaryngology Author(s): Dianne G. Valenzuela, Divjot Singh Kumar, Cheryl Labelle Atkins, Alison Beers, Frederick K. Kozak, Neil K. Chadha IntroductionThe Auditory Brainstem Response (ABR) test is used to identify hearing loss and measure hearing thresholds of infants and children who cannot be tested using standard behavioral hearing testing methods. In order for the ABR to yield useful data, a child ... περισσότερα »

Is there too much stress on stress? – The Guardian

Αλέξανδρος ΣφακιανάκηςστοMedicine by Sfakianakis G. AlexandrosΠριν από 20 δευτερόλεπτα
[image: 1PwgtFy] The Guardian *Is there too much stress on stress?* *The Guardian* To a man and woman, they complained of “a coated *tongue*, more or less diffuse aches and pains in the joints, intestinal disturbances and loss of appetite. … he decided, was a name for all those diverse agents and the apparently nonspecific effects *…* from #ORL-AlexandrosSfakianakis via simeraentaxei on Inoreader http://ift.tt/1oB3qdi via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1SpvlJn via IFTTT

Use of Intravenous Propranolol for Control of a Large Cervicofacial Hemangioma in a Critically Ill Neonate

Αλέξανδρος ΣφακιανάκηςστοMedicine by Sfakianakis G. AlexandrosΠριν από 20 δευτερόλεπτα
Use of Intravenous Propranolol for Control of a Large Cervicofacial Hemangioma in a Critically Ill Neonate via International Journal of Pediatric Otorhinolaryngology Publication date: Available online 12 February 2016 *Source:*International Journal of Pediatric Otorhinolaryngology Author(s): Shanik J. Fernando, Sabra Leitenberger, Matt Majerus, Alfons Krol, Carol J. MacArthur Cervicofacial segmental infantile hemangiomas (IH) may result in airway obstruction requiring use of propranolol to induce hemangioma regression and reestablish the airway. We present the first case using intraveno... περισσότερα »

Post-operative risk-recall in patients undergoing total thyroidectomy

Αλέξανδρος ΣφακιανάκηςστοMedicine by Sfakianakis G. AlexandrosΠριν από 20 δευτερόλεπτα
Informed consent: do information pamphlets improve post-operative risk-recall in patients undergoing total thyroidectomy: prospective randomized control study: Abstract BackgroundInformed consent consists of basic five elements: voluntarism, capacity, disclosure, understanding, and ultimate decision-making. Physician disclosure, patient understanding, and information retention are all essential in the doctor-patient relationship. This is inclusive of helping patients make and manage their decisions and expectations better and also to deal with any consequences and/or complications ... περισσότερα »

Prophylactic neck dissection for low-risk differentiated thyroid cancers

Αλέξανδρος ΣφακιανάκηςστοMedicine by Sfakianakis G. AlexandrosΠριν από 20 δευτερόλεπτα
Prophylactic neck dissection for low-risk differentiated thyroid cancers: Risk-benefit analysis: Abstract Background The benefit of neck dissection is the subject of debate in differentiated thyroid cancer (DTC). We analyze the risk-benefit of neck dissection for low-risk DTC without detectable lymph nodes. Methods We conducted a retrospective study from 1983 to 2003; which included 295 patients without detectable lymph nodes who were treated by thyroidectomy with (C+) or without (C-) neck dissection. All patients had iodine131 therapy. We compared the frequency of remission, disease... περισσότερα »

Postoperative radio(chemo)therapy in patients with head and neck cancer

Αλέξανδρος ΣφακιανάκηςστοMedicine by Sfakianakis G. AlexandrosΠριν από 20 δευτερόλεπτα
Survival and overall treatment time after postoperative radio(chemo)therapy in patients with head and neck cancer: [image: cover.gif?v=1&s=f31d30ee0afa0d30e14f3c30] Abstract Background Generally, overall treatment time for patients with locally advanced head and neck cancer should be as short as reasonably possible. This analysis was undertaken to determine at what overall treatment time additional survival/locoregional control benefits could be achieved compared to a 100-day cutoff. Methods Clinical impact of overall treatment time was assessed in 272 patients by multivariable C... περισσότερα »

Transoral laser microsurgery for locally advanced (T3–T4a) supraglottic squamous cell carcinoma

Αλέξανδρος ΣφακιανάκηςστοMedicine by Sfakianakis G. AlexandrosΠριν από 20 δευτερόλεπτα
Transoral laser microsurgery for locally advanced (T3–T4a) supraglottic squamous cell carcinoma: Sixteen years of experience: [image: cover.gif?v=1&s=f31d30ee0afa0d30e14f3c30] Abstract Background Controversy exists regarding treatment of advanced laryngeal cancer. The purpose of this study was to evaluate the oncologic and functional outcomes of T3 to T4a supraglottic squamous carcinomas treated with transoral laser microsurgery (TLM). Methods We conducted a retrospective analysis from an SPSS database. Primary outcomes were: locoregional control, overall survival (OS), disease-s... περισσότερα »

Endoscopic cricopharyngeal myotomy with CO2 laser surgery

Αλέξανδρος ΣφακιανάκηςστοMedicine by Sfakianakis G. AlexandrosΠριν από 20 δευτερόλεπτα
Outcomes of endoscopic cricopharyngeal myotomy with CO2 laser surgery: A retrospective study of 47 patients: [image: cover.gif?v=1&s=f31d30ee0afa0d30e14f3c30] ABSTRACT Background Endoscopic cricopharyngeal myotomy (ECPM) using CO2 laser surgery presents a less invasive treatment technique when compared to transcervical cricopharyngeal myotomy. Methods Forty-seven patients who underwent ECPM from 2002 until 2013 were included in this study. Patient characteristics, and preoperative and postoperative outcome and complications were scored by retrospective chart review and by using t... περισσότερα »

Prosthodontic rehabilitation of edentulous oral cancer patients

Αλέξανδρος ΣφακιανάκηςστοMedicine by Sfakianakis G. AlexandrosΠριν από 20 δευτερόλεπτα
Functional benefits of implants placed during ablative surgery: A 5-year prospective study on the prosthodontic rehabilitation of 56 edentulous oral cancer patients: [image: cover.gif?v=1&s=f31d30ee0afa0d30e14f3c30] Abstract Background The timing of placement as well as the functional benefit of interforaminal implants in edentulous patients treated for oral cancer is unclear. Methods Fifty-six patients were recruited at 2 institutions. In 1 institution, interforaminal implants were placed during ablative surgery, the other institution used conventional prosthodontics with optiona... περισσότερα »

Bacteremia in Children Hospitalized with Respiratory Syncytial Virus Infection

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 21 δευτερόλεπτα
Bacteremia in Children Hospitalized with Respiratory Syncytial Virus Infection: [image: journal.pone.0146599.t001] by Miriam Cebey-López, Jacobo Pardo-Seco, Alberto Gómez-Carballa, Nazareth Martinón-Torres, José María Martinón-Sánchez, Antonio Justicia-Grande, Irene Rivero-Calle, Elli Pinnock, Antonio Salas, Colin Fink, Federico Martinón-Torres, GENDRES network Background The risk of bacteremia is considered low in children with acute bronchiolitis. However the rate of occult bacteremia in infants with RSV infection is not well established. The aim was to determine the actua... περισσότερα »

Electroencephalographic Fractal Dimension

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 22 δευτερόλεπτα
in Healthy Ageing and Alzheimer’s Disease: by Fenne Margreeth Smits, Camillo Porcaro, Carlo Cottone, Andrea Cancelli, Paolo Maria Rossini, Franca Tecchio Brain activity is complex; a reflection of its structural and functional organization. Among other measures of complexity, the fractal dimension is emerging as being sensitive to neuronal damage secondary to neurological and psychiatric diseases. Here, we calculated Higuchi’s fractal dimension (HFD) in resting-state eyes-closed electroencephalography (EEG) recordings from 41 healthy controls (age: 20–89 years) and 67 Alzheimer’s ... περισσότερα »

The Mammalian Feeding Muscle Ontology (MFMO)

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 22 δευτερόλεπτα
Muscle Logic: New Knowledge Resource for Anatomy Enables Comprehensive Searches of the Literature on the Feeding Muscles of Mammals: by Robert E. Druzinsky, James P. Balhoff, Alfred W. Crompton, James Done, Rebecca Z. German, Melissa A. Haendel, Anthony Herrel, Susan W. Herring, Hilmar Lapp, Paula M. Mabee, Hans-Michael Muller, Christopher J. Mungall, Paul W. Sternberg, Kimberly Van Auken, Christopher J. Vinyard, Susan H. Williams, Christine E. Wall Background In recent years large bibliographic databases have made much of the published literature of biology available for searche... περισσότερα »

Staphylococcus aureus during Exponential Growth Phase Enhance IL-12 Production in Dendritic Cells

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 22 δευτερόλεπτα
D-Alanylation of Teichoic Acids and Loss of Poly-N-Acetyl Glucosamine in Staphylococcus aureus during Exponential Growth Phase Enhance IL-12 Production in Murine Dendritic Cells: by Lisbeth Drozd Lund, Hanne Ingmer, Hanne Frøkiær *Staphylococcus aureus* is a major human pathogen that has evolved very efficient immune evading strategies leading to persistent colonization. During different stages of growth, *S*. *aureus* express various surface molecules, which may affect the immune stimulating properties, but very little is known about their role in immune stimulation and evasion. ... περισσότερα »

A Rapid and Low-Cost Polymerase chain reaction (PCR) Thermal Cycler for Infectious Disease Diagnostics

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 22 δευτερόλεπτα
A Rapid and Low-Cost PCR Thermal Cycler for Infectious Disease Diagnostics: [image: journal.pone.0149150.g001] by Kamfai Chan, Pui-Yan Wong, Peter Yu, Justin Hardick, Kah-Yat Wong, Scott A. Wilson, Tiffany Wu, Zoe Hui, Charlotte Gaydos, Season S. Wong The ability to make rapid diagnosis of infectious diseases broadly available in a portable, low-cost format would mark a great step forward in global health. Many molecular diagnostic assays are developed based on using thermal cyclers to carry out polymerase chain reaction (PCR) and reverse-transcription PCR for DNA and RNA amplif... περισσότερα »

Intestinal Air-Breathing,Accessory Air-Breathing Organs (ABOs)

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 25 δευτερόλεπτα
High-Throughput Sequencing Identifies MicroRNAs from Posterior Intestine of Loach (Misgurnus anguillicaudatus) and Their Response to Intestinal Air-Breathing Inhibition: [image: journal.pone.0149123.g001] by Songqian Huang, Xiaojuan Cao, Xianchang Tian, Weimin Wang MicroRNAs (miRNAs) exert important roles in animal growth, immunity, and development, and regulate gene expression at the post-transcriptional level. Knowledges about the diversities of miRNAs and their roles in accessory air-breathing organs (ABOs) of fish remain unknown. In this work, we used high-throughput sequen... περισσότερα »

Vitamin D Supplementation Reduces Induction of Epithelial-Mesenchymal Transition in Allergen Sensitized and Challenged Mice

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 25 δευτερόλεπτα
Vitamin D Supplementation Reduces Induction of Epithelial-Mesenchymal Transition in Allergen Sensitized and Challenged Mice: [image: journal.pone.0149180.g001] by Kimberly D. Fischer, Sannette C. Hall, Devendra K. Agrawal Asthma is a chronic disease of the lung associated with airway hyperresponsiveness (AHR), airway obstruction and airway remodeling. Airway remodeling involves differentiation of airway epithelial cells into myofibroblasts via epithelial-mesenchymal transition (EMT) to intensify the degree of subepithelial fibrosis. EMT involves loss in E-cadherin with an incre... περισσότερα »

Decompressive Craniectomy on Perihematomal Edema in Patients with Intracerebral Hemorrhage

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 27 δευτερόλεπτα
Effect of Decompressive Craniectomy on Perihematomal Edema in Patients with Intracerebral Hemorrhage: [image: journal.pone.0149169.t001] by Christian Fung, Michael Murek, Pascal P. Klinger-Gratz, Michael Fiechter, Werner J. Z’Graggen, Oliver P. Gautschi, Marwan El-Koussy, Jan Gralla, Karl Schaller, Martin Zbinden, Marcel Arnold, Urs Fischer, Heinrich P. Mattle, Andreas Raabe, Jürgen Beck Background Perihematomal edema contributes to secondary brain injury in the course of intracerebral hemorrhage. The effect of decompressive surgery on perihematomal edema after intracerebral ... περισσότερα »

Methotrexate-induced testis injury

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 28 δευτερόλεπτα
Protective effects of propolis on methotrexate-induced testis injury in rat via Biomedicine & Pharmacotherapy Publication date: April 2016 *Source:*Biomedicine & Pharmacotherapy, Volume 79 Author(s): Mehmet Fatih Sönmez, Kübra Tuğçe Çilenk, Derya Karabulut, Sunay Ünalmış, Erkan Deligönül, İsmet Öztürk, Emin Kaymak Propolis is an adhesive substance which is collected and used by honeybees. Propolis is a potent antioxidant and a free radical scavenger. This study was designed to determine whether propolis could protect against dysfunction and oxidative stress induced by methotrexate-induc... περισσότερα »

Relapsing Polychondritis Initiating with Unexplained Fever

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 29 δευτερόλεπτα
A Case of Relapsing Polychondritis Initiating with Unexplained Fever: Relapsing polychondritis (RP) is a rare autoimmune disease affecting the multiple organ system. Here, we describe a case of RP initially presenting with high fever. The patient was referred to our hospital for further examination of fever of unknown origin (FUO). On admission, the patient reported dry cough in addition to fever. On physical examination, her red, swollen ears were noted, attributed on histology to inflammation with auricular perichondritis. She was diagnosed with RP and treated with oral prednisone... περισσότερα »

Preliminary Evaluation of Functional Swallow After Total Laryngectomy Using High-Resolution Manometry

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 29 δευτερόλεπτα
Preliminary Evaluation of Functional Swallow After Total Laryngectomy Using High-Resolution Manometry: Introduction: Understanding of swallowing pressures after total laryngectomy (TL) and what constitutes a "functional" swallow are limited. Mobile structures are altered or removed after TL, with consequent effects on pressure profiles. High-resolution manometry (HRM) can characterize these pressures. Methods: Six TL subjects without dysphagia and 6 controls underwent pharyngeal HRM. Timing and pressure variables for the velopharynx, mesopharynx, and upper esophageal sphincter (UES... περισσότερα »

Agreement between health utility instruments in cochlear implantation

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 31 δευτερόλεπτα
Agreement between health utility instruments in cochlear implantation: Objectives The objectives of our study were threefold: to compare health utility scores measured with different health utility instruments in adult patients with bilateral deafness, to compare the change in health utility scores after unilateral or bilateral cochlear implantation using the different health utility instruments and to assess which health utility instrument would be the most appropriate for future studies on cochlear implantation. Design A prospective study. Setting The data for this article were col... περισσότερα »

Management of Primary Malignant Lymphoma of the Parotid Gland

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 31 δευτερόλεπτα
Management of Primary Malignant Lymphoma of the Parotid Gland in a series of 745 patients: 1.From 1980 to 2014, 745 consecutive patients were undergoing parotid surgery in our institution and 90 (12%) were diagnosed with a malignant tumour, with primary lymphoma of the parotid gland being diagnosed in 19 patients (21.1% of all malignant tumours and 2.6% of all parotidectomies). 2.Follicular lymphoma (n=9) was the most common histological type, followed by marginal cell lymphoma (n=7). The majority of cases were low grade lymphoma. 3.There are no distinguishing clinical or radiologic... περισσότερα »

Molecular Markers for Indeterminate Thyroid Nodules : Afirma GEC molecular test,ThyroSeq v.2 molecular test

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 31 δευτερόλεπτα
Randomized Trial Comparing Performance of Molecular Markers for Indeterminate Thyroid Nodules: *Condition*: Thyroid *Interventions*: Other: Afirma GEC; Other: ThyroSeq v.2 *Sponsor*: Jonsson Comprehensive Cancer Center Groups/CohortsAssigned Interventions Afirma GEC single molecular test GEC of collected tissue Other: Afirma GEC Afirma GEC molecular test on collected thyroid tissue ThyroSeq v.2 single molecular test ThyroSeq v.2 of collected tissue Other: ThyroSeq v.2 ThyroSeq v.2 molecular test on collected thyroid tissue Detailed Description: 1. All patients undergoing ... περισσότερα »

Research Tissue Biobanks

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 34 δευτερόλεπτα
Challenges for quality management in implementation, maintenance, and sustainability of research tissue biobanks: AbstractAvailability of high-quality human tissue samples and access to associated histopathological and clinical data is essential for basic and translational biomedical research, especially in areas of personalized medicine, drug, and biomarker development and mechanistically oriented biomedical research projects. Therefore, it is pivotal to establish and maintain quality-assured tissue biobanks that provide high-quality biomaterial to research thereby increasing the ... περισσότερα »

Famciclovir may be the antiviral agent of choice in the treatment of patients with severe facial palsy

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 34 δευτερόλεπτα
*Comparison of acyclovir and famciclovir for the treatment of Bell’s palsy: * Abstract*The relative effectiveness of acyclovir and famciclovir in the treatment of Bell’s palsy is unclear. This study therefore compared recovery outcomes in patients with Bell’s palsy treated with acyclovir and famciclovir. The study cohort consisted of patients with facial palsy who visited the outpatient clinic between January 2006 and January 2014. Patients were treated with prednisolone plus either acyclovir (n = 457) or famciclovir (n = 245). Patient outcomes were measured using the House-Brackma...περισσότερα »

Acyclovir and famciclovir for the treatment of Bell’s palsy : Treatment with steroid plus famciclovir was more effective than treatment with steroid plus acyclovir in patients with severe facial palsy. Famciclovir may be the antiviral agent of choice in the treatment of patients with severe facial palsy.

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 34 δευτερόλεπτα
Comparison of acyclovir and famciclovir for the treatment of Bell’s palsy: AbstractThe relative effectiveness of acyclovir and famciclovir in the treatment of Bell’s palsy is unclear. This study therefore compared recovery outcomes in patients with Bell’s palsy treated with acyclovir and famciclovir. The study cohort consisted of patients with facial palsy who visited the outpatient clinic between January 2006 and January 2014. Patients were treated with prednisolone plus either acyclovir (*n* = 457) or famciclovir (*n* = 245). Patient outcomes were measured using the House-Brackma... περισσότερα »

Stationary facial nerve paresis after surgery for recurrent parotid pleomorphic adenoma

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 34 δευτερόλεπτα
Stationary facial nerve paresis after surgery for recurrent parotid pleomorphic adenoma: a follow-up study of 219 cases in Denmark in the period 1985–2012: AbstractThe purpose was to assess degree of permanent facial nerve dysfunction after surgery for recurrent pleomorphic adenoma (RPA) of the parotid gland, including variables that might influence re-operation outcomes. Nationwide retrospective longitudinal cohort study including a questionnaire survey of patients undergoing surgery for RPA. Of 219 living patients, 198 (92 %) responded and 127 (63 %) reported no facial dysfuncti... περισσότερα »

Balloon dilation of the eustachian tube

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 42 δευτερόλεπτα
: a tympanometric outcomes analysis via Latest Results for Journal of Otolaryngology - Head & Neck Surgery AbstractBackgroundEustachian tube dysfunction (ETD) is a common medical issue, occurring in at least 1 % of the adult population. Patients suffering from ET dysfunction typically present with complaints of hearing loss or sensation of pressure or plugged ear, which can lead to impaired quality of life. Over time ETD can result in conductive hearing loss or choleastatoma formation. Effective theraputic options for ET dysfunction are few. Eustachian tube balloon dilation is a novel... περισσότερα »

Bone invasion in small-sized (4cm or less) oral squamous cell carcinoma

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 42 δευτερόλεπτα
Staging significance of bone invasion in small-sized (4cm or less) oral squamous cell carcinoma as defined by the American Joint Committee on Cancer via ScienceDirect Publication: Oral Oncology Publication date: Available online 12 February 2016 *Source:*Oral Oncology Author(s): Su Kyung Kuk, Hye Jung Yoon, Seong Doo Hong, Sam Pyo Hong, Jae Il Lee ObjectivesThe staging significance of bone invasion is controversial in oral squamous cell carcinoma (OSCC) cases with tumors measuring 4cm or less according to the American Joint Committee on Cancer (AJCC). Our aim was to retrospectively exa... περισσότερα »

IJMS, Vol. 17, Pages 36: Drosophotoxicology: An Emerging Research Area for Assessing Nanoparticles Interaction with Living Organisms

Alexandros G. SfakianakisστοΝοσολογίαΠριν από 43 δευτερόλεπτα
The rapid development of nanotechnology allowed the fabrication of a wide range of different nanomaterials, raising many questions about their safety and potential risks for the human health and environment. Most of the current nanotoxicology research is not standardized, hampering any comparison or reproducibility of the obtained results. Drosophotoxicology encompasses the plethora of methodological approaches addressing the use of Drosophila melanogaster as a choice organism in toxicology studies. Drosophila melanogaster model offers several important advantages, such as a relat... περισσότερα »

Dihydrotestosterone on the Development of Graves' Disease in Female

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 44 δευτερόλεπτα
The Influence of Dihydrotestosterone on the Development of Graves' Disease in Female BALB/c Mice: Thyroid , Vol. 0, No. 0. Author information Lianye Liu,1,2,* Liping Wu,1,* Aibo Gao,1 Qi Zhang,1 Hongjun Lv,1 Li Xu,1 Chuanqing Xie,1 Qian Wu,3Peng Hou,1 and Bingyin Shi1 1Department of Endocrinology, The First Affiliated Hospital of Xi'an Jiaotong University Health Science Center, Xi'an, China. 2Department of Nephrology and Endocrinology, Weinan Central Hospital, Weinan, China. 3Department of Epidemiology and Biostatistics, School of Public Heath, Xi'an Jiaotong University Health Scie... περισσότερα »

Pulmonary Metastases Arising from Follicular Cell–Derived Thyroid Cancer

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 45 δευτερόλεπτα
Time Course and Predictors of Structural Disease Progression in Pulmonary Metastases Arising from Follicular Cell–Derived Thyroid Cancer: Thyroid , Vol. 0, No. 0. Author information Mona M. Sabra,1 Ronald Ghossein,2 and R. Michael Tuttle1 1Endocrinology Service, Department of Medicine, Memorial Sloan-Kettering Cancer Center and Weill-Cornell College of Medicine, New York, New York. 2Department of Pathology, Memorial Sloan-Kettering Cancer Center and Weill-Cornell College of Medicine, New York, New York. Address correspondence to: *Mona M. Sabra, MD* *Memorial Sloan-Kettering Cancer ... περισσότερα »

Acute Otitis Media Infection caused by Haemophilus influenzae

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 45 δευτερόλεπτα
Serum Cytokine Biomarkers Accurately Predict Presence of Acute Otitis Media Infection and Recovery caused by Haemophilus influenzae via International Journal of Pediatric Otorhinolaryngology Publication date: Available online 12 February 2016 *Source:*International Journal of Pediatric Otorhinolaryngology Author(s): Michael E. Pichichero, Anthony Almudevar ObjectiveWe sought to develop an optimal model using a combination of serum biomarker pro-inflammatory and dampening inflammatory cytokine proteins to predict the presence of acute otitis media (AOM) infection and recovery caused by N... περισσότερα »

Chloral Hydrate Sedation for Auditory Brainstem Response (ABR) Testing in Children

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 50 δευτερόλεπτα
: Safety and Effectiveness via International Journal of Pediatric Otorhinolaryngology Publication date: Available online 13 February 2016 *Source:*International Journal of Pediatric Otorhinolaryngology Author(s): Dianne G. Valenzuela, Divjot Singh Kumar, Cheryl Labelle Atkins, Alison Beers, Frederick K. Kozak, Neil K. Chadha IntroductionThe Auditory Brainstem Response (ABR) test is used to identify hearing loss and measure hearing thresholds of infants and children who cannot be tested using standard behavioral hearing testing methods. In order for the ABR to yield useful data, a child ... περισσότερα »

Use of Intravenous Propranolol for Control of a Large Cervicofacial Hemangioma in a Critically Ill Neonate

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 50 δευτερόλεπτα
Use of Intravenous Propranolol for Control of a Large Cervicofacial Hemangioma in a Critically Ill Neonate via International Journal of Pediatric Otorhinolaryngology Publication date: Available online 12 February 2016 *Source:*International Journal of Pediatric Otorhinolaryngology Author(s): Shanik J. Fernando, Sabra Leitenberger, Matt Majerus, Alfons Krol, Carol J. MacArthur Cervicofacial segmental infantile hemangiomas (IH) may result in airway obstruction requiring use of propranolol to induce hemangioma regression and reestablish the airway. We present the first case using intraveno... περισσότερα »

Post-operative risk-recall in patients undergoing total thyroidectomy

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 50 δευτερόλεπτα
Informed consent: do information pamphlets improve post-operative risk-recall in patients undergoing total thyroidectomy: prospective randomized control study: Abstract BackgroundInformed consent consists of basic five elements: voluntarism, capacity, disclosure, understanding, and ultimate decision-making. Physician disclosure, patient understanding, and information retention are all essential in the doctor-patient relationship. This is inclusive of helping patients make and manage their decisions and expectations better and also to deal with any consequences and/or complications... περισσότερα »

Prophylactic neck dissection for low-risk differentiated thyroid cancers

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 52 δευτερόλεπτα
Prophylactic neck dissection for low-risk differentiated thyroid cancers: Risk-benefit analysis: Abstract Background The benefit of neck dissection is the subject of debate in differentiated thyroid cancer (DTC). We analyze the risk-benefit of neck dissection for low-risk DTC without detectable lymph nodes. Methods We conducted a retrospective study from 1983 to 2003; which included 295 patients without detectable lymph nodes who were treated by thyroidectomy with (C+) or without (C-) neck dissection. All patients had iodine131 therapy. We compared the frequency of remission, diseas... περισσότερα »

Postoperative radio(chemo)therapy in patients with head and neck cancer

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 52 δευτερόλεπτα
Survival and overall treatment time after postoperative radio(chemo)therapy in patients with head and neck cancer: [image: cover.gif?v=1&s=f31d30ee0afa0d30e14f3c30] Abstract Background Generally, overall treatment time for patients with locally advanced head and neck cancer should be as short as reasonably possible. This analysis was undertaken to determine at what overall treatment time additional survival/locoregional control benefits could be achieved compared to a 100-day cutoff. Methods Clinical impact of overall treatment time was assessed in 272 patients by multivariable ... περισσότερα »

Transoral laser microsurgery for locally advanced (T3–T4a) supraglottic squamous cell carcinoma

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 53 δευτερόλεπτα
Transoral laser microsurgery for locally advanced (T3–T4a) supraglottic squamous cell carcinoma: Sixteen years of experience: [image: cover.gif?v=1&s=f31d30ee0afa0d30e14f3c30] Abstract Background Controversy exists regarding treatment of advanced laryngeal cancer. The purpose of this study was to evaluate the oncologic and functional outcomes of T3 to T4a supraglottic squamous carcinomas treated with transoral laser microsurgery (TLM). Methods We conducted a retrospective analysis from an SPSS database. Primary outcomes were: locoregional control, overall survival (OS), disease-... περισσότερα »

Endoscopic cricopharyngeal myotomy with CO2 laser surgery

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 53 δευτερόλεπτα
Outcomes of endoscopic cricopharyngeal myotomy with CO2 laser surgery: A retrospective study of 47 patients: [image: cover.gif?v=1&s=f31d30ee0afa0d30e14f3c30] ABSTRACT Background Endoscopic cricopharyngeal myotomy (ECPM) using CO2 laser surgery presents a less invasive treatment technique when compared to transcervical cricopharyngeal myotomy. Methods Forty-seven patients who underwent ECPM from 2002 until 2013 were included in this study. Patient characteristics, and preoperative and postoperative outcome and complications were scored by retrospective chart review and by using ...περισσότερα »

IJMS, Vol. 17, Pages 36: Drosophotoxicology: An Emerging Research Area for Assessing Nanoparticles Interaction with Living Organisms

Alexandros G. SfakianakisστοΝοσολογίαΠριν από 54 δευτερόλεπτα
The rapid development of nanotechnology allowed the fabrication of a wide range of different nanomaterials, raising many questions about their safety and potential risks for the human health and environment. Most of the current nanotoxicology research is not standardized, hampering any comparison or reproducibility of the obtained results. Drosophotoxicology encompasses the plethora of methodological approaches addressing the use of Drosophila melanogaster as a choice organism in toxicology studies. Drosophila melanogaster model offers several important advantages, such as a relat... περισσότερα »

Information, Vol. 7, Pages 5: The Treewidth of Induced Graphs of Conditional Preference Networks Is Small

Alexandros G. SfakianakisστοΝοσολογίαΠριν από 54 δευτερόλεπτα
Conditional preference networks (CP-nets) are recently an emerging topic as a graphical model for compactly representing ordinal conditional preference relations on multi-attribute domains. As we know, the treewidth, which can decrease the solving complexity for many intractability problems, is exactly a fundamental property of a graph. Therefore, we can utilize treewidth to solve some reasoning tasks on induced graphs, such as the dominance queries on the CP-nets in the future. In this paper, we present an efficient algorithm for computing the treewidth of induced graphs of CP-ne... περισσότερα »

Sustainability, Vol. 8, Pages 153: Measuring the Level of Industrial Green Development and Exploring Its Influencing Factors: Empirical Evidence from China’s 30 Provinces

Alexandros G. SfakianakisστοΝοσολογίαΠριν από 54 δευτερόλεπτα
Nowadays, with the green economy becoming mainstream in the world, an industrial revolution as the core of green development has emerged. Based on the empirical evidence from China's 30 provinces, this study establishes an evaluation index system of China's industrial green development and applies the analytic hierarchy process to determine the indices' weights and properties to measure the level of industrial green development in China's 30 provinces. Then, an empirical study is conducted to explore the relevant factors influencing China's industrial green development by using th... περισσότερα »

Prosthodontic rehabilitation of edentulous oral cancer patients

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 54 δευτερόλεπτα
Functional benefits of implants placed during ablative surgery: A 5-year prospective study on the prosthodontic rehabilitation of 56 edentulous oral cancer patients: [image: cover.gif?v=1&s=f31d30ee0afa0d30e14f3c30] Abstract Background The timing of placement as well as the functional benefit of interforaminal implants in edentulous patients treated for oral cancer is unclear. Methods Fifty-six patients were recruited at 2 institutions. In 1 institution, interforaminal implants were placed during ablative surgery, the other institution used conventional prosthodontics with option...περισσότερα »

Impact of neck failure on survival in older patients with differentiated thyroid cancer

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 54 δευτερόλεπτα
Impact of neck failure on survival in older patients with differentiated thyroid cancer: [image: cover.gif?v=1&s=f31d30ee0afa0d30e14f3c30] Abstract Background Regional recurrence of differentiated thyroid cancer (DTC) is often salvaged with neck dissection without survival penalty. It is unknown whether recurrence may be associated with inferior survival in older patients. Methods Surveillance, Epidemiology, and End Results (SEER) and Medicare data were linked to identify patients age ≥65 with nonmetastatic DTC. Patients undergoing neck dissection >6 months after their initial d... περισσότερα »

Cancer-testis antigens (CTAs) represent an immunogenic family of cancer-specific proteins and thus represent an attractive target for immunotherapy.

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 54 δευτερόλεπτα
Expression and clinical significance of MAGE and NY-ESO-1 cancer-testis antigens in adenoid cystic carcinoma of the head and neck: Abstract Background Adenoid cystic carcinoma (ACC) of the head and neck is a rare but highly malignant tumor. Cancer-testis antigens (CTAs) represent an immunogenic family of cancer-specific proteins and thus represent an attractive target for immunotherapy. Methods Eighty-four cases of ACC were identified, the CTAs pan-Melanoma antigen (pan-MAGE; M3H67) and New York esophageal squamous cell carcinoma (NY-ESO-1; E978) were detected immunohistochemically ... περισσότερα »

Expression and clinical significance of MAGE and NY-ESO-1 cancer-testis antigens in adenoid cystic carcinoma of the head and neck

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 54 δευτερόλεπτα
Expression and clinical significance of MAGE and NY-ESO-1 cancer-testis antigens in adenoid cystic carcinoma of the head and neck: Abstract Background Adenoid cystic carcinoma (ACC) of the head and neck is a rare but highly malignant tumor. Cancer-testis antigens (CTAs) represent an immunogenic family of cancer-specific proteins and thus represent an attractive target for immunotherapy. Methods Eighty-four cases of ACC were identified, the CTAs pan-Melanoma antigen (pan-MAGE; M3H67) and New York esophageal squamous cell carcinoma (NY-ESO-1; E978) were detected immunohistochemically ... περισσότερα »

Gastro-oesophageal reflux is worthy of further investigation in individuals with Prader-Willi syndrome.

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 56 δευτερόλεπτα
Prader–Willi syndrome *From Wikipedia, the free encyclopedia* Prader-Willi Syndrome Classification and external resources Specialty *Medical genetics, pediatrics* ICD-10 *Q87.1* ICD-9-CM *759.81* OMIM *176270* DiseasesDB *10481* MedlinePlus *001605* eMedicine *ped/1880* Patient UK *Prader–Willi syndrome* MeSH *D011218* GeneReviews - *Prader-Willi Syndrome* Orphanet *739* *Prader–Willi syndrome (/ˈprɑːdər ˈvɪli/; abbreviated PWS) is a rare genetic disorder in which seven genes (or some subset thereof) onchromosome 15 (q 11–13) are deleted or unexpressed (chromosome 15q partial de... περισσότερα »

Chronic Migraine in Children and Adolescents

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 58 δευτερόλεπτα
Chronic Migraine in Children and Adolescents: AbstractChronic migraine is defined as having more than 15 headache days in a month, half of these showing migraine features, for at least 3 months. It is a chronic painful syndrome with aspects such as psychiatric comorbid, decreased quality of life, and environmental and intrinsic psychological factors that make face-to-face treatment difficult. Children and adolescent migraine differ from adults as a result of growing brain and evolving disorder. In this paper, we will emphasize the definition, diagnosis, epidemiology, burden of life... περισσότερα »

Four-Duct Ligation for the Treatment of Sialorrhea in Children.

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 58 δευτερόλεπτα
Four-Duct Ligation for the Treatment of Sialorrhea in Children.: JAMA Otolaryngol Head Neck Surg. 2016 Feb 11; Authors: Khan WU, Islam A, Fu A, Blonski DC, Zaheer S, McCann CA, Joseph MS, Perlin R, Khan R, Campisi P Abstract Importance: The 4-duct ligation procedure has appeal for its surgical simplicity and limited invasiveness in the management of pediatric sialorrhea. However, more information is required to understand the benefits, risks, success rates, and long-term effects of this intervention. Objectives: To report the clinical outcomes of the 4-duct ligation procedure in p... περισσότερα »

Association of Compliance With Process-Related Quality Metrics and Improved Survival in Oral Cavity Squamous Cell Carcinoma.

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 59 δευτερόλεπτα
Association of Compliance With Process-Related Quality Metrics and Improved Survival in Oral Cavity Squamous Cell Carcinoma.: JAMA Otolaryngol Head Neck Surg. 2016 Feb 11; Authors: Graboyes EM, Gross J, Kallogjeri D, Piccirillo JF, Al-Gilani M, Stadler ME, Nussenbaum B Abstract Importance: Quality metrics for patients with head and neck cancer are available, but it is unknown whether compliance with these metrics is associated with improved patient survival. Objective: To identify whether compliance with various process-related quality metrics is associated with improved survival ... περισσότερα »

Sternocleidomastoid pyomyositis

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 1 ώρα
Sternocleidomastoid pyomyositis via European Annals of Otorhinolaryngology, Head and Neck Diseases Publication date: Available online 12 February 2016 *Source:*European Annals of Otorhinolaryngology, Head and Neck Diseases Author(s): E.J. Gosnell, B. Anwar, V. Varadarajan, S. Freeman IntroductionPyogenic myositis (pyomyositis) represents a bacterial infection of striated muscle. Predominantly associated with tropical regions and commonly caused by Staphylococcus aureus, the incidence of cervical pyomyositis is rare. To our knowledge, we report the first case of group A streptococcal cer... περισσότερα »

The OTOSPEECH automated scoring software package for speech audiometry

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 1 ώρα
Validation of the French-language version of T via European Annals of Otorhinolaryngology, Head and Neck Diseases Publication date: Available online 12 February 2016 *Source:*European Annals of Otorhinolaryngology, Head and Neck Diseases Author(s): F. Venail, E. Legris, B. Vaerenberg, J.-L. Puel, P.J. Govaerts, J.C. Ceccato ObjectivesTo validate a novel speech audiometry method using customized self-voice recorded word lists with automated scoring.Patients and methodsThe self-voice effect was investigated by comparing results with prerecorded or self-recorded CVC (consonant-vowel-conson... περισσότερα »

Questionable Necessity for Removing Submandibular Gland in Neck Dissection in Squamous Cell Carcinoma of Oral Cavity

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 1 ώρα
Questionable Necessity for Removing Submandibular Gland in Neck Dissection in Squamous Cell Carcinoma of Oral Cavity: AbstractTo assess whether submandibular gland is involved by metastasis in cases of oral cavity squamous cell carcinomas. It was a retrospective study, where we reviewed the records of the patients who underwent neck dissections for Squamous Cell Carcinoma of the oral cavity. It included 112 patients who had undergone 115 neck dissections (three patients had undergone bilateral neck dissection), either therapeutic or prophylactic. No pathologic evidence of metastasi... περισσότερα »

Effectiveness of superselective intra-arterial chemoradiotherapy targeting retropharyngeal lymph node metastasis

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 1 ώρα
Effectiveness of superselective intra-arterial chemoradiotherapy targeting retropharyngeal lymph node metastasis: AbstractWe sought to evaluate the efficacy and feasibility of superselective intra-arterial infusion of high-dose cisplatin with concomitant radiotherapy (hereafter RADPLAT) for head and neck squamous cell cancer (hereafter HNSCC) patients with retropharyngeal lymph node (hereafter RPLN) metastasis. A retrospective case series review was conducted at University medical center in Japan. Ten HNSCC patients with RPLN metastasis treated by RADPLAT were analyzed. The ascendi... περισσότερα »

Cholesteatoma growth patterns: are there audiometric differences between posterior epitympanic and posterior mesotympanic cholesteatoma?

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 1 ώρα
Cholesteatoma growth patterns: are there audiometric differences between posterior epitympanic and posterior mesotympanic cholesteatoma?: AbstractThe objective of this is to verify whether the hearing impairment caused by posterior epitympanic differed from that caused by posterior mesotympanic cholesteatomas by a cross-sectional study. We evaluated 264 ears of patients with cholesteatoma, who had not been subjected to ear surgery. Otoendoscopy and pure-tone audiometry were performed. Analyzed route involved in cholesteatoma formation: posterior epitympanic or posterior mesotympani... περισσότερα »

Predictors of post-treatment smoking and drinking behavior of head and neck cancer survivors: results of a population-based survey

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 1 ώρα
Predictors of post-treatment smoking and drinking behavior of head and neck cancer survivors: results of a population-based survey: AbstractPredictors for smoking and alcohol drinking behavior were investigated in head and neck cancer survivors (HNCS) with survivorship of ≥6 months. 165 HNCS registered in a regional cancer registry and treated 2005–2014 were included. Patients completed a survey including the Fagerström Test for nicotine dependence and the Alcohol Use Disorders Identification Test. Smoking and drinking cessation rates were 51 and 13 %, respectively. Multinomial log... περισσότερα »

Editorial Board

Publication date: April 2016 Source:Neurobiology of Disease, Volume 88 from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1Tj4Cyj via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174

Emergency response plan: Model-based assessment with multi-state degradation

Publication date: June 2016 Source:Safety Science, Volume 85 Author(s): Clément Girard, Pierre David, Eric Piatyszek, Jean-Marie Flaus Local Emergency Response Plans (LERP) must be assessed before being triggered, to ensure proper execution of missions in a crisis situation. However, there is very little research on plan assessment methods. Plan assessment has traditionally involved consideration of […]

Topical Ethyl chloride to reduce pain associated with venous catheterization: A randomized crossover trial

Publication date: Available online 13 February 2016 Source:The American Journal of Emergency Medicine Author(s): Kurt Fossum, Sue L. Love, Michael D. April ObjectiveTo compare pain associated with venous catheterization following administration of topical ethyl chloride versus placebo among emergency department (ED) healthcare providers.MethodsWe conducted a randomized, double-blind, placebo-controlled, crossover trial among a convenience sample of […]

Heart stopping honey–not just Turkish honey

Publication date: Available online 13 February 2016 Source:The American Journal of Emergency Medicine Author(s): Mary Yuling Lim, Dong Haur Phua, Chee Kheong Ooi ‘Mad-honey’ poisoning has been well reported in the Eastern Black Sea region of Turkey. The toxin implicated is grayanotoxin which is found in honey derived from nectar of plants belonging to Rhodendron […]

Prediction of en-route complications during inter-facility transport by outcome predictive scores in emergency department

Publication date: Available online 13 February 2016 Source:The American Journal of Emergency Medicine Author(s): Y.K. Wong, C.T. Lui, K.K. Li, C.Y. Wong, M.M. Lee, W.L. Tong, K.L. Ong, S.Y.H. Tang ObjectiveTo determine the accuracy of the outcome predictive scores (MEWS, HOTEL score and SCS) in predicting en-route complications during inter-facility transport in emergency department.Design.Retrospective cohort […]

Tonsillectomy Surgery PreOp® Patient Engagement and Education

Tonsillectomy Surgery PreOp® Patient Engagement and Education StoreMD™ for Physician videos: http://store.preop.com Patient Education Company Your doctor has recommended that you – or your child – undergo surgery to remove you or your child’s tonsils. But what does that actually mean? Your tonsils are located in the throat at the back of your mouth – […]

Injury, Inflammation and the Emergence of Human-Specific Genes

Abstract In light of the central role of inflammation in normal wound repair and regeneration, we hypothesize that the preponderance of human-specific genes expressed in human inflammatory cells is commensurate with the genetic versatility of inflammatory response and the emergence of injuries associated with uniquely hominid behaviors, like a bipedal posture and the use of […]

Journal of Pathogen Biology, Year 2015, Issue 12 -New Issue Alert.

From: order@email.oriprobe.com Date: February 14, 2016 at 08:03AM New Issue TOC Alert Dear Valued Customer, We are pleased to deliver your requested table of contents alert for Journal of Pathogen Biology. Year 2015 Issue 12 is now available on CAOD. In this issue: zhong guo bing yuan sheng wu xue za zhi gao yue (《中国病原生物学杂志》稿约) […]

High-Throughput Sequencing Identifies MicroRNAs from Posterior Intestine of Loach (Misgurnus anguillicaudatus) and Their Response to Intestinal Air-Breathing Inhibition

by Songqian Huang, Xiaojuan Cao, Xianchang Tian, Weimin Wang MicroRNAs (miRNAs) exert important roles in animal growth, immunity, and development, and regulate gene expression at the post-transcriptional level. Knowledges about the diversities of miRNAs and their roles in accessory air-breathing organs (ABOs) of fish remain unknown. In this work, we used high-throughput sequencing to identify […]

Correction: Functional Assessment of Cardiac Responses of Adult Zebrafish (Danio rerio) to Acute and Chronic Temperature Change Using High-Resolution Echocardiography

by Ling Lee, Christine E. Genge, Michelle Cua, Xiaoye Sheng, Kaveh Rayani, Mirza F. Beg, Marinko V. Sarunic, Glen F. Tibbits from Uncategorized via xlomafota13 on Inoreader http://ift.tt/1KOyzUr via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1Kih1jn via IFTTT

Muscle Logic: New Knowledge Resource for Anatomy Enables Comprehensive Searches of the Literature on the Feeding Muscles of Mammals

by Robert E. Druzinsky, James P. Balhoff, Alfred W. Crompton, James Done, Rebecca Z. German, Melissa A. Haendel, Anthony Herrel, Susan W. Herring, Hilmar Lapp, Paula M. Mabee, Hans-Michael Muller, Christopher J. Mungall, Paul W. Sternberg, Kimberly Van Auken, Christopher J. Vinyard, Susan H. Williams, Christine E. Wall Background In recent years large bibliographic databases […]

Pathogens, Vol. 5, Pages 19: Why Serological Responses during Cystitis are Limited

The high frequency of urinary tract infections (UTIs), some of which appear to be endogenous relapses rather than reinfections by new isolates, point to defects in the host’s memory immune response. It has been known for many decades that, whereas kidney infections evoked an antibody response to the infecting bacteria, infections limited to the bladder […]

Applied Sciences, Vol. 6, Pages 50: Dynamics of Carrier Transport in Nanoscale Materials: Origin of Non-Drude Behavior in the Terahertz Frequency Range

Alexandros G. SfakianakisστοΝοσολογίαΠριν από 1 ώρα
It is known that deviation from the Drude law for free carriers is dramatic in most electronically conductive nanomaterials. We review recent studies of the conductivity of nanoscale materials at terahertz (THz) frequencies. We suggest that among a variety of theoretical formalisms, a model of series sequence of transport involving grains and grain boundaries provides a reasonable explanation of Lorentz-type resonance (non-Drude behavior) in nanomaterials. Of particular interest is why do free carriers exhibit a Lorentz-type resonance. from #Medicine via ola Kala on Inoreader http... περισσότερα »

Shandong Journal of Biomedical Engineering, Year 2015, Issue 04 -New Issue Alert.

From: order@email.oriprobe.com Date: February 14, 2016 at 08:04AM New Issue TOC Alert Dear Valued Customer, We are pleased to deliver your requested table of contents alert for Shandong Journal of Biomedical Engineering. Year 2015 Issue 04 is now available on CAOD. In this issue: zhong wen he xin qi kan yao mu zong lan ru […]

Pharmacy Today , Year 2015, Issue 12 -New Issue Alert.

From: order@email.oriprobe.com Date: February 14, 2016 at 08:04AM New Issue TOC Alert Dear Valued Customer, We are pleased to deliver your requested table of contents alert for Pharmacy Today . Year 2015 Issue 12 is now available on CAOD. In this issue: jin ri yao xue za zhi 2015 nian di 12 qi ji xu […]

Journal of Biomedical Engineering Research, Year 2015, Issue 04 -New Issue Alert.

From: order@email.oriprobe.com Date: February 14, 2016 at 08:04AM New Issue TOC Alert Dear Valued Customer, We are pleased to deliver your requested table of contents alert for Journal of Biomedical Engineering Research. Year 2015 Issue 04 is now available on CAOD. In this issue: zhong wen he xin qi kan yao mu zong lan ru […]

Pharmaceutical & Engineering Design, Year 2015, Issue 06 -New Issue Alert.

From: order@email.oriprobe.com Date: February 14, 2016 at 08:03AM New Issue TOC Alert Dear Valued Customer, We are pleased to deliver your requested table of contents alert for Pharmaceutical & Engineering Design. Year 2015 Issue 06 is now available on CAOD. In this issue: Analysis and Optimization of Typical Temperature Control Scheme for Reboiler in Distillation […]

Journal of Pathogen Biology, Year 2015, Issue 12 -New Issue Alert.

From: order@email.oriprobe.com Date: February 14, 2016 at 08:03AM New Issue TOC Alert Dear Valued Customer, We are pleased to deliver your requested table of contents alert for Journal of Pathogen Biology. Year 2015 Issue 12 is now available on CAOD. In this issue: zhong guo bing yuan sheng wu xue za zhi gao yue (《中国病原生物学杂志》稿约) […]

Is there too much stress on stress? – The Guardian

orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 1 ώρα
The Guardian Is there too much stress on stress? The Guardian To a man and woman, they complained of “a coated tongue, more or less diffuse aches and pains in the joints, intestinal disturbances and loss of appetite. … he decided, was a name for all those diverse agents and the apparently nonspecific effects …… Continue reading Is there too much stress on stress? – The Guardian

Journal of Pathogen Biology, Year 2015, Issue 12 -New Issue Alert.

From: order@email.oriprobe.com Date: February 14, 2016 at 08:03AM New Issue TOC Alert Dear Valued Customer, We are pleased to deliver your requested table of contents alert for Journal of Pathogen Biology. Year 2015 Issue 12 is now available on CAOD. In this issue: zhong guo bing yuan sheng wu xue za zhi gao yue (《中国病原生物学杂志》稿约) […]

Topical Ethyl chloride to reduce pain associated with venous catheterization: A randomized crossover trial

Publication date: Available online 13 February 2016 Source:The American Journal of Emergency Medicine Author(s): Kurt Fossum, Sue L. Love, Michael D. April ObjectiveTo compare pain associated with venous catheterization following administration of topical ethyl chloride versus placebo among emergency department (ED) healthcare providers.MethodsWe conducted a randomized, double-blind, placebo-controlled, crossover trial among a convenience sample of […]

Heart stopping honey–not just Turkish honey

Publication date: Available online 13 February 2016 Source:The American Journal of Emergency Medicine Author(s): Mary Yuling Lim, Dong Haur Phua, Chee Kheong Ooi ‘Mad-honey’ poisoning has been well reported in the Eastern Black Sea region of Turkey. The toxin implicated is grayanotoxin which is found in honey derived from nectar of plants belonging to Rhodendron […]

Prediction of en-route complications during inter-facility transport by outcome predictive scores in emergency department

Publication date: Available online 13 February 2016 Source:The American Journal of Emergency Medicine Author(s): Y.K. Wong, C.T. Lui, K.K. Li, C.Y. Wong, M.M. Lee, W.L. Tong, K.L. Ong, S.Y.H. Tang ObjectiveTo determine the accuracy of the outcome predictive scores (MEWS, HOTEL score and SCS) in predicting en-route complications during inter-facility transport in emergency department.Design.Retrospective cohort […]

Bacterial Peritonitis

Bacterial peritonitis: This bacterial infection inside of the abdomen involves the inner lining tissue, the peritoneum. Bacterial peritonitis can be spontaneous, such as can occur in people with severe alcoholic liver disease, or be caused by bacteria contaminating the abdomen, such as from a knife or gunshot wound or as a complication of appendicitis. Bacterial […]

Tonsillectomy Surgery PreOp® Patient Engagement and Education

Tonsillectomy Surgery PreOp® Patient Engagement and Education StoreMD™ for Physician videos: http://store.preop.com Patient Education Company Your doctor has recommended that you – or your child – undergo surgery to remove you or your child’s tonsils. But what does that actually mean? Your tonsils are located in the throat at the back of your mouth – […]

Pharmaceutical & Engineering Design, Year 2015, Issue 06 -New Issue Alert.

From: order@email.oriprobe.com Date: February 14, 2016 at 08:03AM New Issue TOC Alert Dear Valued Customer, We are pleased to deliver your requested table of contents alert for Pharmaceutical & Engineering Design. Year 2015 Issue 06 is now available on CAOD. In this issue: Analysis and Optimization of Typical Temperature Control Scheme for Reboiler in Distillation […]

Sensors, Vol. 16, Pages 227: Removing the Interdependency between Horizontal and Vertical Eye-Movement Components in Electrooculograms

This paper introduces a method to remove the unwanted interdependency between vertical and horizontal eye-movement components in electrooculograms (EOGs). EOGs have been widely used to estimate eye movements without a camera in a variety of human-computer interaction (HCI) applications using pairs of electrodes generally attached either above and below the eye (vertical EOG) or to […]

Shandong Journal of Biomedical Engineering, Year 2015, Issue 04 -New Issue Alert.

From: order@email.oriprobe.com Date: February 14, 2016 at 08:04AM New Issue TOC Alert Dear Valued Customer, We are pleased to deliver your requested table of contents alert for Shandong Journal of Biomedical Engineering. Year 2015 Issue 04 is now available on CAOD. In this issue: zhong wen he xin qi kan yao mu zong lan ru […]

Overactive Thyroid Linked to Breast Cancer Risk – Philly.com

Latinos Health Overactive Thyroid Linked to Breast Cancer Risk Philly.com 11, 2016 (HealthDay News) — Women who have an overactive thyroid gland might be at greater risk for breast cancer, a new study suggests. A team of Danish researchers found that women with the condition — called hyperthyroidism — appeared to face an … Thyroid […]

Pathogens, Vol. 5, Pages 19: Why Serological Responses during Cystitis are Limited

Alexandros G. SfakianakisστοNews in OtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 1 ώρα
The high frequency of urinary tract infections (UTIs), some of which appear to be endogenous relapses rather than reinfections by new isolates, point to defects in the host's memory immune response. It has been known for many decades that, whereas kidney infections evoked an antibody response to the infecting bacteria, infections limited to the bladder failed to do so. We have identified the existence of a broadly immunosuppressive transcriptional program associated with the bladder, but not the kidneys, during infection of the urinary tract that is dependent on bladder mast cells... περισσότερα »

Sensors, Vol. 16, Pages 227: Removing the Interdependency between Horizontal and Vertical Eye-Movement Components in Electrooculograms

Alexandros G. SfakianakisστοNews in OtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 1 ώρα
This paper introduces a method to remove the unwanted interdependency between vertical and horizontal eye-movement components in electrooculograms (EOGs). EOGs have been widely used to estimate eye movements without a camera in a variety of human-computer interaction (HCI) applications using pairs of electrodes generally attached either above and below the eye (vertical EOG) or to the left and right of the eyes (horizontal EOG). It has been well documented that the vertical EOG component has less stability than the horizontal EOG one, making accurate estimation of the vertical loc... περισσότερα »

IJMS, Vol. 17, Pages 143: Hyaluronidase Inhibitory Activity of Pentacylic Triterpenoids from Prismatomeris tetrandra (Roxb.) K. Schum: Isolation, Synthesis and QSAR Study

Alexandros G. SfakianakisστοNews in OtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 1 ώρα
The mammalian hyaluronidase degrades hyaluronic acid by the cleavage of the β-1,4-glycosidic bond furnishing a tetrasaccharide molecule as the main product which is a highly angiogenic and potent inducer of inflammatory cytokines. Ursolic acid 1, isolated from Prismatomeris tetrandra, was identified as having the potential to develop inhibitors of hyaluronidase. A series of ursolic acid analogues were either synthesized via structure modification of ursolic acid 1 or commercially obtained. The evaluation of the inhibitory activity of these compounds on the hyaluronidase enzyme was ... περισσότερα »

IJMS, Vol. 17, Pages 143: Hyaluronidase Inhibitory Activity of Pentacylic Triterpenoids from Prismatomeris tetrandra (Roxb.) K. Schum: Isolation, Synthesis and QSAR Study

Alexandros G. SfakianakisστοNews in OtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 1 ώρα
The mammalian hyaluronidase degrades hyaluronic acid by the cleavage of the β-1,4-glycosidic bond furnishing a tetrasaccharide molecule as the main product which is a highly angiogenic and potent inducer of inflammatory cytokines. Ursolic acid 1, isolated from Prismatomeris tetrandra, was identified as having the potential to develop inhibitors of hyaluronidase. A series of ursolic acid analogues were either synthesized via structure modification of ursolic acid 1 or commercially obtained. The evaluation of the inhibitory activity of these compounds on the hyaluronidase enzyme was ... περισσότερα »

Pathogens, Vol. 5, Pages 19: Why Serological Responses during Cystitis are Limited

Αλέξανδρος ΣφακιανάκηςστοMedicine by Alexandros G.SfakianakisΠριν από 1 ώρα
The high frequency of urinary tract infections (UTIs), some of which appear to be endogenous relapses rather than reinfections by new isolates, point to defects in the host's memory immune response. It has been known for many decades that, whereas kidney infections evoked an antibody response to the infecting bacteria, infections limited to the bladder failed to do so. We have identified the existence of a broadly immunosuppressive transcriptional program associated with the bladder, but not the kidneys, during infection of the urinary tract that is dependent on bladder mast cells... περισσότερα »

Sensors, Vol. 16, Pages 227: Removing the Interdependency between Horizontal and Vertical Eye-Movement Components in Electrooculograms

Αλέξανδρος ΣφακιανάκηςστοMedicine by Alexandros G.SfakianakisΠριν από 1 ώρα
This paper introduces a method to remove the unwanted interdependency between vertical and horizontal eye-movement components in electrooculograms (EOGs). EOGs have been widely used to estimate eye movements without a camera in a variety of human-computer interaction (HCI) applications using pairs of electrodes generally attached either above and below the eye (vertical EOG) or to the left and right of the eyes (horizontal EOG). It has been well documented that the vertical EOG component has less stability than the horizontal EOG one, making accurate estimation of the vertical loc... περισσότερα »

IJMS, Vol. 17, Pages 143: Hyaluronidase Inhibitory Activity of Pentacylic Triterpenoids from Prismatomeris tetrandra (Roxb.) K. Schum: Isolation, Synthesis and QSAR Study

Αλέξανδρος ΣφακιανάκηςστοMedicine by Alexandros G.SfakianakisΠριν από 1 ώρα
The mammalian hyaluronidase degrades hyaluronic acid by the cleavage of the β-1,4-glycosidic bond furnishing a tetrasaccharide molecule as the main product which is a highly angiogenic and potent inducer of inflammatory cytokines. Ursolic acid 1, isolated from Prismatomeris tetrandra, was identified as having the potential to develop inhibitors of hyaluronidase. A series of ursolic acid analogues were either synthesized via structure modification of ursolic acid 1 or commercially obtained. The evaluation of the inhibitory activity of these compounds on the hyaluronidase enzyme was ... περισσότερα »

Overactive Thyroid Linked to Breast Cancer Risk – Philly.com

orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 2 ώρες
Latinos Health Overactive Thyroid Linked to Breast Cancer Risk Philly.com 11, 2016 (HealthDay News) — Women who have an overactive thyroid gland might be at greater risk for breast cancer, a new study suggests. A team of Danish researchers found that women with the condition — called hyperthyroidism — appeared to face an … Thyroid… Continue reading Overactive Thyroid Linked to Breast Cancer Risk – Philly.com

IJMS, Vol. 17, Pages 143: Hyaluronidase Inhibitory Activity of Pentacylic Triterpenoids from Prismatomeris tetrandra (Roxb.) K. Schum: Isolation, Synthesis and QSAR Study

orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 2 ώρες
The mammalian hyaluronidase degrades hyaluronic acid by the cleavage of the β-1,4-glycosidic bond furnishing a tetrasaccharide molecule as the main product which is a highly angiogenic and potent inducer of inflammatory cytokines. Ursolic acid 1, isolated from Prismatomeris tetrandra, was identified as having the potential to develop inhibitors of hyaluronidase. A series of ursolic acid… Continue reading IJMS, Vol. 17, Pages 143: Hyaluronidase Inhibitory Activity of Pentacylic Triterpenoids from Prismatomeris tetrandra (Roxb.) K. Schum: Isolation, Synthesis and QSAR Study

Topical Ethyl chloride to reduce pain associated with venous catheterization: A randomized crossover trial

orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 2 ώρες
Publication date: Available online 13 February 2016 Source:The American Journal of Emergency Medicine Author(s): Kurt Fossum, Sue L. Love, Michael D. April ObjectiveTo compare pain associated with venous catheterization following administration of topical ethyl chloride versus placebo among emergency department (ED) healthcare providers.MethodsWe conducted a randomized, double-blind, placebo-controlled, crossover trial among a convenience sample of… Continue reading Topical Ethyl chloride to reduce pain associated with venous catheterization: A randomized crossover trial

Heart stopping honey–not just Turkish honey

orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 2 ώρες
Publication date: Available online 13 February 2016 Source:The American Journal of Emergency Medicine Author(s): Mary Yuling Lim, Dong Haur Phua, Chee Kheong Ooi ‘Mad-honey’ poisoning has been well reported in the Eastern Black Sea region of Turkey. The toxin implicated is grayanotoxin which is found in honey derived from nectar of plants belonging to Rhodendron… Continue reading Heart stopping honey–not just Turkish honey

Pathogens, Vol. 5, Pages 19: Why Serological Responses during Cystitis are Limited

Alexandros G. SfakianakisστοΝοσολογίαΠριν από 2 ώρες
The high frequency of urinary tract infections (UTIs), some of which appear to be endogenous relapses rather than reinfections by new isolates, point to defects in the host's memory immune response. It has been known for many decades that, whereas kidney infections evoked an antibody response to the infecting bacteria, infections limited to the bladder failed to do so. We have identified the existence of a broadly immunosuppressive transcriptional program associated with the bladder, but not the kidneys, during infection of the urinary tract that is dependent on bladder mast cells... περισσότερα »

Overactive Thyroid Linked to Breast Cancer Risk – Philly.com

Latinos Health Overactive Thyroid Linked to Breast Cancer Risk Philly.com 11, 2016 (HealthDay News) — Women who have an overactive thyroid gland might be at greater risk for breast cancer, a new study suggests. A team of Danish researchers found that women with the condition — called hyperthyroidism — appeared to face an … Thyroid […]

IJMS, Vol. 17, Pages 143: Hyaluronidase Inhibitory Activity of Pentacylic Triterpenoids from Prismatomeris tetrandra (Roxb.) K. Schum: Isolation, Synthesis and QSAR Study

The mammalian hyaluronidase degrades hyaluronic acid by the cleavage of the β-1,4-glycosidic bond furnishing a tetrasaccharide molecule as the main product which is a highly angiogenic and potent inducer of inflammatory cytokines. Ursolic acid 1, isolated from Prismatomeris tetrandra, was identified as having the potential to develop inhibitors of hyaluronidase. A series of ursolic acid […]

Journal of Biomedical Engineering Research, Year 2015, Issue 04 -New Issue Alert.

From: order@email.oriprobe.com Date: February 14, 2016 at 08:04AM New Issue TOC Alert Dear Valued Customer, We are pleased to deliver your requested table of contents alert for Journal of Biomedical Engineering Research. Year 2015 Issue 04 is now available on CAOD. In this issue: zhong wen he xin qi kan yao mu zong lan ru […]

Shandong Journal of Biomedical Engineering, Year 2015, Issue 04 -New Issue Alert.

From: order@email.oriprobe.com Date: February 14, 2016 at 08:04AM New Issue TOC Alert Dear Valued Customer, We are pleased to deliver your requested table of contents alert for Shandong Journal of Biomedical Engineering. Year 2015 Issue 04 is now available on CAOD. In this issue: zhong wen he xin qi kan yao mu zong lan ru […]

Pharmacy Today , Year 2015, Issue 12 -New Issue Alert.

From: order@email.oriprobe.com Date: February 14, 2016 at 08:04AM New Issue TOC Alert Dear Valued Customer, We are pleased to deliver your requested table of contents alert for Pharmacy Today . Year 2015 Issue 12 is now available on CAOD. In this issue: jin ri yao xue za zhi 2015 nian di 12 qi ji xu […]

IJMS, Vol. 17, Pages 143: Hyaluronidase Inhibitory Activity of Pentacylic Triterpenoids from Prismatomeris tetrandra (Roxb.) K. Schum: Isolation, Synthesis and QSAR Study

The mammalian hyaluronidase degrades hyaluronic acid by the cleavage of the β-1,4-glycosidic bond furnishing a tetrasaccharide molecule as the main product which is a highly angiogenic and potent inducer of inflammatory cytokines. Ursolic acid 1, isolated from Prismatomeris tetrandra, was identified as having the potential to develop inhibitors of hyaluronidase. A series of ursolic acid […]

Overactive Thyroid Linked to Breast Cancer Risk – Philly.com

Latinos Health Overactive Thyroid Linked to Breast Cancer Risk Philly.com 11, 2016 (HealthDay News) — Women who have an overactive thyroid gland might be at greater risk for breast cancer, a new study suggests. A team of Danish researchers found that women with the condition — called hyperthyroidism — appeared to face an … Thyroid […]

Δεν υπάρχουν σχόλια:

Δημοσίευση σχολίου