An Atypical Case of Lymphocytic Panhypophysitis in a Pregnant Woman.
We describe a case of lymphocytic panhypophysitis (LPH) in a 30-year-old woman presenting with throbbing headaches and vision changes during her third trimester. LPH is the rarest subclassification of lymphocytic hypophysitis; it is typically found in males and has not previously been associated with pregnancy. Anterior and posterior pituitary deficits together with headaches should raise a high degree of suspicion regarding the possibility of LPH. The atypical magnetic resonance imaging finding of a heterogeneous pituitary mass additionally raised concern about pituitary apoplexy. ... περισσότερα »
Effect of noninvasive focused ultrasound stimulation on gamma oscillations in rat hippocampus.
In recent years, noninvasive focused ultrasound stimulation (FUS), with the advantage of high spatial resolution and high penetration depth, has developed rapidly for modulating neuron activities in the brain. Gamma oscillations serve to synchronize neurons and play important roles in cortical information processing and cognitive function. However, how FUS modulates gamma oscillations in the rat hippocampus is not well understood. In this work, we characterized the interactions between the gamma amplitude and phases of the delta, theta, and alpha bands during FUS. Our results show t...περισσότερα »
Railway suicide in England and Wales 2000–2013: a time-trends analysis
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A combination of three-dimensional printing and computer-assisted virtual surgical procedure for preoperative planning of acetabular fracture reduction
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The utility of bolus IV nicardipine for hypertensive emergencies in the emergency department
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Telemedicine provides non-inferior research informed consent for remote study enrollment: a randomized controlled trial
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Traumatic injuries among adult obese patients in southern Taiwan: a cross-sectional study based on a trauma registry system
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The experience of emotional wellbeing for patients with physical injury: A qualitative follow up study
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Postpartum Contraception: An exploratory study of lactation consultants’ knowledge and practices
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Point of care testing for group A streptococci in patients presenting with pharyngitis will improve appropriate antibiotic prescription
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Lack of agreement on distal radius fracture treatment
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Effective treatment of gastrointestinal bleeding with thalidomide - Chances and limitations
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Stabilisation of infected peri-articular nonunions with an antibiotic impregnated cement coated locking plate: Technique and indications
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Occupational fatalities among young workers in the United States: 2001–2012
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Does Routine Midazolam Administration Prior to Nasogastric Tube Insertion in the Emergency Department Decreases Patients’ Pain? (a Pilot Study)
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Craniofacial disorders associated with airway obstruction in the neonate
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Surgical outcomes of temporary short-segment instrumentation without augmentation for thoracolumbar burst fractures
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Is pain really undertreated? Challenges of addressing pain in trauma patients during prehospital transport and trauma resuscitation
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N-octanoyl dopamine treatment exerts renoprotective properties in acute kidney injury but not in renal allograft recipients
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Noncardiac challenges in the cardiac ICU: feeding, growth and gastrointestinal complications, anticoagulation, and analgesia
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Employer reasons for failing to report eligible workers’ compensation claims in the BLS survey of occupational injuries and illnesses
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Liuweiwuling tablets protect against acetaminophen hepatotoxicity: What is the protective mechanism?
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Resolution of Cardiogenic Shock Using Echocardiography-Guided Pacing Optimization in Intensive Care: A Case Series.
[image: wk-health-logo.gif] Objective: Inotropic and vasopressor drugs are routinely used in critically ill patients to maintain adequate blood pressure and cardiac output in patients with cardiogenic shock although potentially at the expense of increasing myocardial oxygen demand. Pacing optimization has been demonstrated as effective in reducing catecholamine requirements in patients with chronic heart failure by improving cardiac efficiency; however, there are no reports relating to the effectiveness of pacemaker optimization on cardiac output in critically ill patients with car... περισσότερα »
Oxygen therapy for cluster headache. A mask comparison trial. A single-blinded, placebo-controlled, crossover study
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 20 δευτερόλεπτα
Purpose The purpose of this article is to investigate possible differences in effect between three types of masks in the acute treatment of cluster headache (CH). Patients and methods Fifty-seven CH patients according to ICHD-II-criteria participated in a single-blinded, semi-randomized, placebo-controlled, crossover inpatient study, and 102 CH attacks were treated with 100% oxygen delivered by […]
Serotonergic mechanisms in the migraine brain – a systematic review
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 20 δευτερόλεπτα
Background Migraine is one of the most common and disabling of all medical conditions, affecting 16% of the general population, causing huge socioeconomic costs globally. Current available treatment options are inadequate. Serotonin is a key molecule in the neurobiology of migraine, but the exact role of brain serotonergic mechanisms remains a matter of controversy. Methods […]
Nodule classification unaffected by segmentation method
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 20 δευτερόλεπτα
The performance of an automated nodule classification scheme doesn’t vary depending… Read more on AuntMinnieEurope.com Related Reading: Algorithm quantifies airway disease at CT Volumetric CT beats RECIST in therapy response Automated technique compares lung screening priors ESTI award goes to CT study of severe emphysema Automated analysis aids lung nodule management from #AlexandrosSfakianakis via Alexandros […]
Swedish group finds unstable plaques with ultrasound
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 20 δευτερόλεπτα
A research team from Lund University in Sweden has developed an ultrasound-based… Read more on AuntMinnieEurope.com Related Reading: 3D ultrasound goes ultrafast Dutch group works on producing clearer ultrasound images WMIC: Landscape changes for coronary artery disease cases DRK: Researchers progress with carotid plaque imaging in stroke Contrast ultrasound may spot early signs of atherosclerosis […]
PET/CT after therapy avoids surgery for head, neck cancer
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 20 δευτερόλεπτα
Using PET/CT scans to assess response to therapy can help patients with head… Read more on AuntMinnieEurope.com Related Reading: FLT-PET could help predict outcome in head and neck cancer FDG-PET/MRI ‘comparable’ to FDG-PET/CT in head/neck cancer Combined PET/CT-perfusion brings results in head, neck cancer Ultrasound and PET/CT catch recurrences of head, neck cancer Emerging techniques […]
How much sugar is hidden in drinks marketed to children? A survey of fruit juices, juice drinks and smoothies
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 20 δευτερόλεπτα
Objective To investigate the amount of sugars in fruit juices, juice drinks and smoothies (FJJDS) marketed to children. Design We surveyed the sugars content (per 100 ml and standardised 200 ml portion) of all FJJDS sold by seven major UK supermarkets (supermarket own and branded products). Only products specifically marketed towards children were included. We […]
Curved versus Straight Stem Uncemented Total Hip Arthroplasty Osteoarthritis Multicenter trial (CUSTOM): design of a prospective blinded randomised controlled multicentre trial
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 20 δευτερόλεπτα
Introduction Answering the demands of an increasingly young and active patient population, recent developments in total hip arthroplasty (THA) have shifted towards minimising tissue damage. The Collum Femoris Preserving (CFP) stem was developed to preserve the trochanteric region of the femur, which potentially preserves the insertion of the gluteus musculature. This might accelerate early postoperative […]
Speaking out about physical harms from tobacco use: response to graphic warning labels among American Indian/Alaska Native communities
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 20 δευτερόλεπτα
Objective This study is the first to explore the impact of graphic cigarette labels with physical harm images on members of American Indian/Alaska Native (AI/AN) communities. The aim of this article is to investigate how AI/AN respond to particular graphic warning labels. Methods The parent study recruited smokers, at-risk smokers and non-smokers from three different […]
Improving the management of behaviour that challenges associated with dementia in care homes: protocol for pharmacy-health psychology intervention feasibility study
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 20 δευτερόλεπτα
Introduction The inappropriate use of antipsychotics in people with dementia for behaviour that challenges is associated with an estimated 1800 deaths annually. However, solely focusing on antipsychotics may transfer prescribing to other equally dangerous psychotropics. Little is known about the role of pharmacists in the management of psychotropics used to treat behaviours that challenge. This […]
Assessing sociodemographic differences (or lack thereof) in prenatal diagnosis of congenital heart defects: a population-based study
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 20 δευτερόλεπτα
Objectives Our main objective was to assess sociodemographic differences in the probability of prenatal diagnosis of congenital heart defects (CHD); we also looked at differences in termination of pregnancy for fetal anomaly (TOPFA). Design Prospective cohort observational study. Setting Population-based cohort of CHD (live births, TOPFA, fetal deaths) born to women residing in the Greater […]
Nontechnical skill assessment for perioperative crisis management simulation training
A proposal for modification of nontechnical skill assessment for perioperative crisis management simulation training: Effectiveness of simulation-based training for improving operating room patient safety is established [1]. Simulation-based education and training are not only effective for acquiring technical skills but also for developing nontechnical skills, such as situation awareness, cooperation, decision making, leadership, and communication in emergency situations. In the operating room, the importance of establishing “perioperative team” training is essential from the viewp... περισσότερα »
Nitrous oxide triggers serotonin syndrome in an anxious adolescent
No laughing matter: nitrous oxide triggers serotonin syndrome in an anxious adolescent: A 16-year-old girl with generalized anxiety disorder and chronic abdominal pain presented for elective upper endoscopy and colonoscopy. Her medication list included fluoxetine and buspirone. Because of severe preoperative anxiety, 50% nitrous oxide was administered to facilitate intravenous catheter placement. Despite this, the patient was extremely tearful, so general anesthesia was induced with the addition of 8% sevoflurane.
Significance of basic airway management simulation training for medical students
Significance of basic airway management simulation training for medical students: [image: main.pdf.png] The American Heart Association cardiopulmonary guidelines recommend not only tracheal intubation (TI), but also bag-valve-mask (BVM) ventilation and supraglottic device (SGD) ventilation in emergent situations. However, given their lack of experience, novice doctors and medical students may find it difficult to implement these recommendations. Here, we used simulation training to have medical students experience the practical difficulties associated with basic airway manageme... περισσότερα »
Inspection of the nasopharynx prior to fiberoptic-guided nasotracheal intubation reduces the risk epistaxis
Inspection of the nasopharynx prior to fiberoptic-guided nasotracheal intubation reduces the risk epistaxis: Various complications may occur during nasotracheal intubation. This may include epistaxis and damage to the nasopharyngeal airway. We tested the hypothesis that the use of fiberoptic bronchoscopy (FOB)–guided intubation is superior to endotracheal tube (ETT) obturated with an inflated esophageal stethoscope. Highlights - •We tested the effectiveness of the fiberoptic bronchoscopy as an intubation guide. - •The insertion of bronchoscope prior to nasal intubation d... περισσότερα »
Amnesia of the Operating Room
Amnesia of the Operating Room in the B-Unaware and BAG-RECALL Clinical Trials: BACKGROUND: Patient memories of the operating room (OR) may serve as the informational basis for assessing satisfaction with individual anesthesiologists. Furthermore, the provision of clinically important information may assume that perioperative memories are retained. Studies assessing the extent of perioperative amnesia and factors associated with perioperative amnesia are sparse. Therefore, we assessed patient amnesia of the OR and of the preoperative holding area in hospitals where midazolam is typic...περισσότερα »
What do patients expect from treatment with Dental Implants? Perceptions, expectations and misconceptions: a multicenter study
Abstract Objective While research in terms of patient-centered care in implant therapy is growing, few studies have investigated patients' initial perceptions prior to consultation with the implant dentist. The aim of this cross-sectional study was to capture patients' initial information level, perceptions, as well as expectations from the implant therapy. Method A 34-item questionnaire was developed to investigate patients' preoperative information, perceptions and expectations from treatment with Dental Implants. The study was conducted in three locations (Hong Kong, SiChuan ... περισσότερα »
Cerebral Gaseous Microemboli are Detectable During Continuous Venovenous Hemodialysis
in Critically Ill Patients: An Observational Pilot Study.: Background: Continuous venovenous hemodialysis (CVVHD) may generate microemboli that cross the pulmonary circulation and reach the brain. The aim of the present study was to quantify (load per time interval) and qualify (gaseous vs. solid) cerebral microemboli (CME), detected as high-intensity transient signals, using transcranial Doppler ultrasound. Materials and Methods: Twenty intensive care unit (ICU group) patients requiring CVVHD were examined. CME were recorded in both middle cerebral arteries for 30 minutes during C...περισσότερα »
Respiratory variation of systolic and diastolic time intervals within radial arterial waveform: •Systolic and diastolic time intervals can be measured in a single arterial waveform. •Systolic and diastolic time variation is achieved through respiratory variation. •Systolic and diastolic time variation can be a surrogate index for SVV and PPV.
Respiratory variation of systolic and diastolic time intervals within radial arterial waveform: a comparison with dynamic preload index: [image: gr1.sml] A blood pressure (BP) waveform contains various pieces of information related to respiratory variation. Systolic time interval (STI) reflects myocardial performance, and diastolic time interval (DTI) represents diastolic filling. This study examined whether respiratory variations of STI and DTI within radial arterial waveform are comparable to dynamic indices. Highlights - •Systolic and diastolic time intervals can be m... περισσότερα »
Should we deactivate vagus nerve stimulator in patients undergoing general anesthesia?
Should we deactivate vagus nerve stimulator in patients undergoing general anesthesia?: [image: article_notepad.gif] Vagal nerve stimulation (VNS) is used as an adjunct in the treatment of epilepsy resistant to pharmacologic interventions [1]. This device, typically implanted subcutaneously in the subpectoral space, delivers small (<0.25 mA) current pulses to the vagal nerve in the neck via tunneled electrodes. Although VNS therapy is rarely associated with complications, bradycardia and asystole have been described during its use [2–4]. Here, we report a patient with VNS device w... περισσότερα »
Post orbit exenteration cases: a “red flag” for airway management.•Patients of orbital exenteration surgeries are at risk of developing orbito nasal fistulas. •Patients with such fistulas become cases of difficult mask ventilation (DMV) in subsequent surgeries. •Air leaks through the orbit during conventional bag mask ventilation. •The letter intends to create awareness about importance of proper history taking and orbital examination in post orbital exenteration patients to anticipate DMV.
Post orbit exenteration cases: a “red flag” for airway management: Highlights - •Patients of orbital exenteration surgeries are at risk of developing orbito nasal fistulas. - •Patients with such fistulas become cases of difficult mask ventilation (DMV) in subsequent surgeries. - •Air leaks through the orbit during conventional bag mask ventilation. - •The letter intends to create awareness about importance of proper history taking and orbital examination in post orbital exenteration patients to anticipate DMV. [image: First page of article]
Myocardial injury after noncardiac surgery
: an underappreciated problem and current challenges.: Purpose of review: To review myocardial injury after noncardiac surgery (MINS), focusing on recent studies, including data on high-sensitivity troponin, which is likely to alter our understanding of MINS. Recent findings: MINS is greatly underappreciated by clinicians, possibly because of its silent presentation. However, MINS is both common and clinically important. In total, 8% of at-risk patients will suffer a MINS, an event that is associated with death within 30 days with an odds ratio of 3.87 (95% CI 2.96-5.08). Most patie... περισσότερα »
Anesthetic considerations for pediatric obesity and adolescent bariatric surgery.
Anesthetic considerations for pediatric obesity and adolescent bariatric surgery.: Purpose of review: Pediatric obesity has become commonplace in our clinical practice, and presents anesthesia providers with numerous challenges. This study provides an up-to-date review of their perioperative care, including the measurement of pediatric obesity, rational drug dosing in obese children, and recent data on bariatric outcomes in adolescents. Recent findings: Pediatric obesity is associated with a number of relevant comorbidities that impact anesthesia care, and specific children are at p... περισσότερα »
Stress Cardiomyopathy After Surgical Treatment
Long-Term Outcomes for Different Forms of Stress Cardiomyopathy After Surgical Treatment for Subarachnoid Hemorrhage.: BACKGROUND: Stress-induced cardiomyopathy (SCM) after subarachnoid hemorrhage (SAH) includes predominant apical or basal regional left ventricular dysfunction (RLVD) with concomitant changes in electrocardiogram or increase in cardiac enzymes. We hypothesized that difference in outcome is associated with the type of RLVD after SAH. METHODS: We studied a single-center retrospective cohort of SAH patients hospitalized between 2000 and 2010 with follow-up until 2013. W... περισσότερα »
Oxygen Reserve Index and Arterial Partial Pressure of Oxygen During Surgery.
The Relationship Between Oxygen Reserve Index and Arterial Partial Pressure of Oxygen During Surgery.: BACKGROUND: The use of intraoperative pulse oximetry (SpO2) enhances hypoxia detection and is associated with fewer perioperative hypoxic events. However, SpO2 may be reported as 98% when arterial partial pressure of oxygen (PaO2) is as low as 70 mm Hg. Therefore, SpO2 may not provide advance warning of falling arterial oxygenation until PaO2 approaches this level. Multiwave pulse co-oximetry can provide a calculated oxygen reserve index (ORI) that may add to information from pulse...περισσότερα »
Antigen-specific TIL therapy for melanoma
Antigen-specific TIL therapy for melanoma: A flexible platform for personalized cancer immunotherapy: [image: cover.gif?v=1&s=c6e9f47bdc4d7d5a610282dc] Tumor infiltrating lymphocyte (TIL) therapy has shown objective clinical response rates of 50% in stage IV melanoma patients in a number of clinical trials. Nevertheless, the majority of patients progress either directly upon therapy or after an initial period of tumor control. Recent data have shown that most TIL products that are used for therapy contain only low frequencies of T cells reactive against known melanoma-associated... περισσότερα »
Post-steroid neuropsychiatric manifestations
are significantly more frequent in SLE compared with other systemic autoimmune diseases and predict better prognosis compared with de novo neuropsychiatric SLE via Autoimmunity Reviews Publication date: Available online 22 March 2016 *Source:*Autoimmunity Reviews Author(s): Yuka Shimizu, Shinsuke Yasuda, Yuki Kako, Shin Nakagawa, Masatoshi Kanda, Ryo Hisada, Kazumasa Ohmura, Sanae Shimamura, Haruki Shida, Yuichiro Fujieda, Masaru Kato, Kenji Oku, Toshiyuki Bohgaki, Tetsuya Horita, Ichiro Kusumi, Tatsuya Atsumi In patients with systemic lupus erythematosus (SLE), neuropsychiatric (NP) ... περισσότερα »
D. pteronyssinus Immunotherapy in Local Allergic Rhinitis
Efficacy and safety of D. pteronyssinus Immunotherapy in Local Allergic Rhinitis: Double-Blind Placebo-Controlled Clinical Trial: [image: cover.gif?v=1&s=eca9898eab49b7d92da2055c] Abstract The effects of allergen immunotherapy (AIT) on local allergic rhinitis (LAR) are largely unknown. We conducted the first randomized, double-blind, placebo-controlled (DBPC), phase II trial of *D. pteronyssinus* (DP) subcutaneous AIT (DP-AIT) on LAR (clinicaltrials. gov identifier: NCT02123316). Thirty-six LAR patients received Pangramin PLUS DP or placebo for 24 months. The primary endpoints w... περισσότερα »
Long-Term Outcomes of External Dacryocystorhinostomy in the Age of Transcanalicular Microendoscopic Techniques
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 50 δευτερόλεπτα
Purpose. This study aimed to evaluate long-term results of external dacryocystorhinostomy (DCR) at a tertiary eye care center specializing in lacrimal duct surgery in Germany. Methods. The medical records of 1010 patients with acquired nasolacrimal duct obstruction (NLDO), who had undergone lacrimal duct surgery at a tertiary eye care center, were reviewed. Only adult patients […]
A Two-Level Additive Schwarz Preconditioning Algorithm for the Weak Galerkin Method for the Second-Order Elliptic Equation
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 50 δευτερόλεπτα
This paper proposes a two-level additive Schwarz preconditioning algorithm for the weak Galerkin approximation of the second-order elliptic equation. In the algorithm, a conforming finite element space is defined on the coarse mesh, and a stable intergrid transfer operator is proposed to exchange the information between the spaces on the coarse mesh and the fine […]
Anti-Inflammatory Effects of GLP-1-Based Therapies beyond Glucose Control
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 50 δευτερόλεπτα
Glucagon-like peptide-1 (GLP-1) is an incretin hormone mainly secreted from intestinal L cells in response to nutrient ingestion. GLP-1 has beneficial effects for glucose homeostasis by stimulating insulin secretion from pancreatic beta-cells, delaying gastric emptying, decreasing plasma glucagon, reducing food intake, and stimulating glucose disposal. Therefore, GLP-1-based therapies such as GLP-1 receptor agonists and inhibitors […]
Prognostic Significance of Neutrophil-to-Lymphocyte Ratio in Patients with Sepsis: A Prospective Observational Study
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 50 δευτερόλεπτα
Background. The neutrophil-to-lymphocyte ratio (NLR) is an easily accessible biological marker that has been reported to represent disease severity. The aim of this study is to investigate the association between NLR and mortality in patients with sepsis. Methods. A total of 333 consecutive adult patients with sepsis were screened for eligibility in this prospective, observational […]
The Effect of Injection Timings on Performance and Emissions of Compressed Natural-Gas Direct Injection Engine
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 50 δευτερόλεπτα
This experimental part investigates the effect of injection timing on performance and emissions of homogenous mixture compressed natural-gas direct injection. The engine of 1.6 L capacity, 4 cylinders, spark ignition, and compression ratio of 14 was used. Performance and emission were recorded under wide-open throttle using an engine control system (Rotronics) and the portable exhaust gas […]
DNA Microarray Analysis of Hypothermic Murine Myocardium to Study Pathophysiology and Identify Forensic Biomarkers
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 50 δευτερόλεπτα
The post DNA Microarray Analysis of Hypothermic Murine Myocardium to Study Pathophysiology and Identify Forensic Biomarkers appeared first on Welcome to Avens. from #AlexandrosSfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1UbqA7f via IFTTT
Pharmacokinetics and pharmacogenetics of Gemcitabine as a mainstay in adult and pediatric oncology: an EORTC-PAMM perspective
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 50 δευτερόλεπτα
Abstract Gemcitabine is an antimetabolite ranking among the most prescribed anticancer drugs worldwide. This nucleoside analog exerts its antiproliferative action after tumoral conversion into active triphosphorylated nucleotides interfering with DNA synthesis and targeting ribonucleotide reductase. Gemcitabine is a mainstay for treating pancreatic and lung cancers, alone or in combination with several cytotoxic drugs (nab-paclitaxel, cisplatin […]
These new articles for The Journal of Clinical Endocrinology & Metabolism are available online
These new articles for The Journal of Clinical Endocrinology & Metabolism are available online ------------------------------ Early Release The Journal of Clinical Endocrinology & Metabolism ------------------------------ [image: Journal of Clinical Endocrinology & Metabolism masthead] ------------------------------ ------------------------------ The Journal of Clinical Endocrinology & Metabolism Home Page Current Issue Past Issues ------------------------------ ------------------------------ ------------------------------ ------------------------------ Long-term Results of GH Treat... περισσότερα »
These new articles for Molecular Endocrinology are available online
These new articles for Molecular Endocrinology are available online ------------------------------ Early Release Molecular Endocrinology ------------------------------ [image: Molecular Endocrinology masthead] ------------------------------ ------------------------------ Molecular Endocrinology Home Page Current Issue Past Issues ------------------------------ ------------------------------ ------------------------------ ------------------------------ Irisin Is Regulated by CAR in Liver and Is a Mediator of Hepatic Glucose and Lipid Metabolism Li Mo, et al. | Molecular Endocrinology...περισσότερα »
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Alexandros G. SfakianakisστοCell and Tissue Research by Alexandros G. SfakianakisΠριν από 54 δευτερόλεπτα
[image: wk-health-logo.gif] No abstract available from Anatomy Pathology via xlomafota13 on Inoreader http://ift.tt/1RisIaQ via IFTTT
Changes in reduced glutathione, oxidized glutathione, and glutathione peroxidase in cats with naturally occurring chronic kidney disease
Alexandros G. SfakianakisστοCell and Tissue Research by Alexandros G. SfakianakisΠριν από 54 δευτερόλεπτα
Abstract Chronic kidney disease (CKD) is one of the most common diseases in geriatric cats. The objective of this study was to determine oxidative stress in CKD cats by measuring changes in reduced glutathione (GSH), oxidized glutathione (GSSG), glutathione peroxidase (GPx), and reduced glutathione to oxidized glutathione (GSH/GSSG) ratio in cats with naturally occurring chronic kidney disease (CKD). Thirteen clinically normal client-owned aged-matched cats and 23 naturally occurring CKD cats were included. Completed blood count, blood urea nitrogen, creatinine, GSH, GPx, GSSG, an... περισσότερα »
The β-1,3-glucan alleviated the hepatotoxicity induced by combination of fipronil and lead in common carp ( Cyprinus carpio)
Alexandros G. SfakianakisστοCell and Tissue Research by Alexandros G. SfakianakisΠριν από 54 δευτερόλεπτα
Abstract The β-1,3-glucan exerts potential antioxidant effect in experimental animal models, but its role in the protection against fipronil and lead-induced toxicity in fish has not been investigated. In this study, we tested the β-1,3-glucan role against fipronil and lead-induced hepatotoxicity in *Cyprinus carpio*. Two hundred seventy *C. carpio* were divided into six groups: control, β-1,3-glucan (0.1 %), fipronil (0.0428 mg/L), lead nitrate (7.3 mg/L), coadministered (fipronil and lead), and coadministered β-1,3-glucan treated. Macrocytic hypochromic anemia with significant d... περισσότερα »
These new articles for Endocrinology are available online
These new articles for Endocrinology are available online ------------------------------ Early Release Endocrinology ------------------------------ [image: Endocrinology masthead] ------------------------------ ------------------------------ Endocrinology Home Page Current Issue Past Issues ------------------------------ ------------------------------ ------------------------------ ------------------------------ Protein-restriction During the Last Third of Pregnancy Malprograms the Neuroendocrine Axes to Induce Metabolic Syndrome in Adult Male Rat Offspring Júlio Cezar de Oliveira, ... περισσότερα »
Water electrolysis on La1−xSrxCoO3−δ perovskite electrocatalysts
Article Perovskite oxides are attractive candidates as catalysts for water electrolysis however their rational design is rare. Here, the authors report a series of cobaltite perovskites where the covalency of the Co-O bond and concentration of oxygen vacancies are controlled, and assess their catalytic performance. Nature Communications doi: 10.1038/ncomms11053 Authors: J. Tyler Mefford, Xi Rong,… Continue reading Water electrolysis on La1−xSrxCoO3−δ perovskite electrocatalysts
Anesthetic considerations for pediatric obesity and adolescent bariatric surgery.
Purpose of review: Pediatric obesity has become commonplace in our clinical practice, and presents anesthesia providers with numerous challenges. This study provides an up-to-date review of their perioperative care, including the measurement of pediatric obesity, rational drug dosing in obese children, and recent data on bariatric outcomes in adolescents. Recent findings: Pediatric obesity is associated… Continue reading Anesthetic considerations for pediatric obesity and adolescent bariatric surgery.
Rotational manipulation of single cells and organisms using acoustic waves
Article The precise rotational manipulation of single cells is technically challenging and relies on the optical, magnetic and electrical properties of the biospecimen. Here the authors develop an acoustic-based, on-chip manipulation method that can rotate single microparticles, cells and organisms. Nature Communications doi: 10.1038/ncomms11085 Authors: Daniel Ahmed, Adem Ozcelik, Nagagireesh Bojanala, Nitesh Nama, Awani Upadhyay,… Continue reading Rotational manipulation of single cells and organisms using acoustic waves
Myocardial injury after noncardiac surgery: an underappreciated problem and current challenges.
Purpose of review: To review myocardial injury after noncardiac surgery (MINS), focusing on recent studies, including data on high-sensitivity troponin, which is likely to alter our understanding of MINS. Recent findings: MINS is greatly underappreciated by clinicians, possibly because of its silent presentation. However, MINS is both common and clinically important. In total, 8% of… Continue reading Myocardial injury after noncardiac surgery: an underappreciated problem and current challenges.
Individual heritable differences result in unique cell lymphocyte receptor repertoires of naïve and antigen-exper ienced cells
Article The diversity of antigen receptor specificities is largely generated by random recombination of its segments. Here the authors show, by genetic comparison of monozygotic twin lymphocyte subsets, that individual genetic and epigenetic biases also contribute to the shape of the B and T cell repertoires. Nature Communications doi: 10.1038/ncomms11112 Authors: Florian Rubelt, Christopher R.… Continue reading Individual heritable differences result in unique cell lymphocyte receptor repertoires of naïve and antigen-exper ienced cells
The Risk of Falls After Total Knee Arthroplasty with the Use of a Femoral Nerve Block Versus an Adductor Canal Block: A Double-Blinded Randomized Controlled Study.
BACKGROUND: Adductor canal block (ACB) has emerged as an appealing alternative to femoral nerve block (FNB) that produces a predominantly sensory nerve block by anesthetizing the saphenous nerve. Studies have shown greater quadriceps strength preservation with ACB compared with FNB, but no advantage has yet been shown in terms of fall risk. The Tinetti scale… Continue reading The Risk of Falls After Total Knee Arthroplasty with the Use of a Femoral Nerve Block Versus an Adductor Canal Block: A Double-Blinded Randomized Controlled Study.
Acetylation of C/EBPα inhibits its granulopoietic function
Article C/EBPα is an essential transcription factor for myeloid lineage commitment. Here, the authors show that acetylation of C/EBPα at K298 and K302, mediated at least in part by GCN5, impairs C/EBPα DNA binding ability and modulates C/EBPα transcriptional activity. Nature Communications doi: 10.1038/ncomms10968 Authors: Deepak Bararia, Hui Si Kwok, Robert S. Welner, Akihiko Numata,… Continue reading Acetylation of C/EBPα inhibits its granulopoietic function
Low-Fidelity Haptic Simulation Versus Mental Imagery Training for Epidural Anesthesia Technical Achievement in Novice Anesthesiology Residents: A Randomized Comparative Study.
BACKGROUND: There are many teaching methods for epidural anesthesia skill acquisition. Previous work suggests that there is no difference in skill acquisition whether novice learners engage in low-fidelity (LF) versus high-fidelity haptic simulation for epidural anesthesia. No study, however, has compared the effect of LF haptic simulation for epidural anesthesia versus mental imagery (MI) training… Continue reading Low-Fidelity Haptic Simulation Versus Mental Imagery Training for Epidural Anesthesia Technical Achievement in Novice Anesthesiology Residents: A Randomized Comparative ... περισσότερα »
High-sensitivity acoustic sensors from nanofibre webs
Article Polymer nanofibres can be used to detect mechanical motion. Here, the authors use electrospun piezoelectric nanofibre webs to detect acoustic waves at frequencies below 500 Hz with a good sensitivity at low pressure levels, and study the impact of the fibres morphology and crystalline phase. Nature Communications doi: 10.1038/ncomms11108 Authors: Chenhong Lang, Jian Fang, Hao… Continue reading High-sensitivity acoustic sensors from nanofibre webs
The Relationship Between Oxygen Reserve Index and Arterial Partial Pressure of Oxygen During Surgery.
BACKGROUND: The use of intraoperative pulse oximetry (SpO2) enhances hypoxia detection and is associated with fewer perioperative hypoxic events. However, SpO2 may be reported as 98% when arterial partial pressure of oxygen (PaO2) is as low as 70 mm Hg. Therefore, SpO2 may not provide advance warning of falling arterial oxygenation until PaO2 approaches this… Continue reading The Relationship Between Oxygen Reserve Index and Arterial Partial Pressure of Oxygen During Surgery.
Prenatal maternal distress affects atopic dermatitis
in offspring mediated by oxidative stress via Allergy and Clinical Immunology Publication date: Available online 23 March 2016 *Source:*Journal of Allergy and Clinical Immunology Author(s): Hyoung Yoon Chang, Dong In Suh, Song-I. Yang, Mi-Jin Kang, So-Yeon Lee, Eun Lee, In Ae Choi, Kyung-Sook Lee, Yee-Jin Shin, Youn Ho Shin, Yoon Hee Kim, Kyung Won Kim, Kangmo Ahn, Hye-Sung Won, Suk-Joo Choi, Soo-Young Oh, Ja-Young Kwon, Young Han Kim, Hee Jin Park, Kyung-Ju Lee, Jong Kwan Jun, Ho-Sung Yu, Seung-Hwa Lee, Bok Kyoung Jung, Ji-Won Kwon, Yoon Kyung Choi, Namhee Do, Yun Jin Bae, Ho Kim, Wo... περισσότερα »
Chitin-fibroin-hydroxyapatite membrane for guided bone regeneration: micro-computed tomography evaluation in a rat model
Chitin-fibroin-hydroxyapatite membrane for guided bone regeneration: micro-computed tomography evaluation in a rat model: Abstract BackgroundIn guided bone regeneration (GBR) technique, many materials have been used for improving biological effectiveness by adding on membranes. The new membrane which was constructed with chitin-fibroin-hydroxyapatite (CNF/HAP) was compared with a collagen membrane (Bio-Gide®) by means of micro-computed tomography. MethodsFifty-four rats were used in this study. A critical-sized (8 mm) bony defect was created in the calvaria with a trephine bur....περισσότερα »
Reduction Malarplasty Using a Zygomatic Arch Lifting Technique
Reduction Malarplasty Using a Zygomatic Arch Lifting Technique via British Association of Plastic Surgeons Publication date: Available online 23 March 2016 *Source:*Journal of Plastic, Reconstructive & Aesthetic Surgery Author(s): Chang Heon Hwang, Myung Chul Lee BackgroundBroad or excessive malar protrusion is a trait associated with aggression and old age in Asian cultures. Although various methods of shifting the zygoma have been introduced for reduction malarplasty, soft tissue sagging and inadequate bony union still remain great challenges. We have devised an arch lifting technique...περισσότερα »
Thiodigalactoside (TDG), a synthetic inhibitor of β-GBP that suppresses tumour growth by inhibiting multiple cancer enhancing activities of β-GBP. Hence, we attempted to understand if disruption of β-GBP functions and indirect inhibition of Treg cells by TDG affect the growth and establishment of oral cancer cells.
TDG shows antitumor activity by β-GBP and Treg inhibition in oral squamous cell carcinoma: Abstract Objective Thiodigalactoside (TDG), a synthetic inhibitor of *β*-GBP that suppresses tumour growth by inhibiting multiple cancer enhancing activities of *β*-GBP. Hence, we attempted to understand if disruption of *β*-GBP functions and indirect inhibition of Treg cells by TDG affect the growth and establishment of oral cancer cells. Method The growth, morphology, cell cycle regulation, apoptosis induction and angiogenesis of oral cancer cell lines (SCC-4, SCC-9, SCC-25) via MACS purifi...περισσότερα »
TDG shows antitumor activity by β-GBP and Treg inhibition in oral squamous cell carcinoma
TDG shows antitumor activity by β-GBP and Treg inhibition in oral squamous cell carcinoma: Abstract Objective Thiodigalactoside (TDG), a synthetic inhibitor of *β*-GBP that suppresses tumour growth by inhibiting multiple cancer enhancing activities of *β*-GBP. Hence, we attempted to understand if disruption of *β*-GBP functions and indirect inhibition of Treg cells by TDG affect the growth and establishment of oral cancer cells. Method The growth, morphology, cell cycle regulation, apoptosis induction and angiogenesis of oral cancer cell lines (SCC-4, SCC-9, SCC-25) via MACS purifi...περισσότερα »
Oral and maxillofacial surgery (OMS) education
The Benefits of Volunteering as an Oral and Maxillofacial Surgery Educator via Oral and Maxillofacial Surgery Publication date: Available online 23 March 2016 *Source:*Journal of Oral and Maxillofacial Surgery Author(s): Ned L. Nix, Lynn G. Beck, Tobias E. Rodriguez There is a faculty shortage crisis in oral and maxillofacial surgery (OMS) education affecting dental students, OMS residents and OMS full-time faculty. This paper is designed to help non-academic OMS practitioners better understand the problem and appreciate the potential benefits of volunteering as a part-time faculty memb...περισσότερα »
The relation between zygomatic implants and symptomatic and radiological modifications of the maxillary sinuses
Are zygomatic implants associated with maxillary sinusitis? via Oral and Maxillofacial Surgery Publication date: Available online 22 March 2016 *Source:*Journal of Oral and Maxillofacial Surgery Author(s): A. D’Agostino, L. Trevisiol, V. Favero, M. Pessina, P. Procacci, P.F. Nocini Aims of the studyThe purpose of the present study was to analyze the relation between zygomatic implants and symptomatic and radiological modifications of the maxillary sinuses.Materials and MethodsA retrospective cohort study of patients who underwent zygomatic implant rehabilitation at the Clinic of Dentis... περισσότερα »
Comparative study of indirect immunofluorescence, enzyme-linked immunosorbent assay, and the Tzanck smear test for the diagnosis of pemphigus
Comparative study of indirect immunofluorescence, enzyme-linked immunosorbent assay, and the Tzanck smear test for the diagnosis of pemphigus: Background Pemphigus is one of the potentially fatal autoimmune blistering diseases. An early and accurate diagnosis is important for prognosis and therapy. It may be difficult to diagnosis based on clinical grounds alone. Direct and indirect immunofluorescence, enzyme-linked immunosorbent assay, the Tzanck smear test, or histopathology are all available for the diagnosis of pemphigus. However, there are no generally accepted diagnostic crit...περισσότερα »
Intraoral Administration of Botulinum Toxin for Trigeminal Neuropathic Pain
Intraoral Administration of Botulinum Toxin for Trigeminal Neuropathic Pain via Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology Publication date: Available online 23 March 2016 *Source:*Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology Author(s): Alberto Herrero Babiloni, Flavia P. Kapos, Donald Nixdorf This article presents two cases of different neuropathic trigeminal pain conditions treated with intraoral botulinum toxin injections. There is a growing body of evidence to support the use of this substance when administered subcutaneously in the treatment of ... περισσότερα »
Complete neurogenic blepharoptosis after minor facial trauma
: a case report via British Journal of Oral and Maxillofacial Surgery Figures and tables 1. [image: Initial presentation. Complete unilateral blepharoptosis without severe swelling ...] 2. [image: Photograph seven weeks after injury. Blepharoptosis is resolved completely.] 3. [image: The anatomical diagram of the oculomotor. The oculomotor nerve (ON) enters the ...] *Source:*British Journal of Oral and Maxillofacial Surgery Author(s): Jongweon Shin, Jung Ho Lee, Young Joon Jun, Young Jin Kim Although mild to moderate blepharoptosis caused by oedema is common aft... περισσότερα »
Bruxism and dental implant treatment complications
Bruxism and dental implant treatment complications: a retrospective comparative study of 98 bruxer patients and a matched group: Abstract Objectives To analyze the complications of dental implant treatment in a group of patients with bruxism in comparison with a matched group of non-bruxers. Material and methods Patients being diagnosed as bruxers were identified within a group of patients consecutively treated with implant-supported prostheses at one specialist clinic, based on the most recent listed sign and symptoms of bruxism according to the International Classification of Sleep... περισσότερα »
Effect of modulation depth, frequency, and intermittence on wind turbine noise annoyancea)
Effect of modulation depth, frequency, and intermittence on wind turbine noise annoyancea): Amplitude modulation (AM) may be an important factor for the perceived annoyance of wind turbinenoise (WTN). Two AM types, typically referred to as “normal AM” (NAM) and “other AM” (OAM), characterize WTN AM, OAM corresponding to having intermittent periods with larger AM depth in lower frequency regions than NAM. The extent to which AM depth, frequency, and type affect WTN annoyance remains uncertain. Moreover, the temporal variations of WTN AM have often not been considered. Here, realisti...περισσότερα »
The acoustical role of vocal tract
in the horseshoe bat, Rhinolophus pusillus: [image: cm_sbs_024_plain.png] The sound field distribution in the vocal tract with a single sound source in the glottis and the transfer function of the supraglottal vocal tract of the horseshoe bat, Rhinolophus pusillus, have been obtained using the finite-element method(FEM) technique. The models of vocal tracts used for FEM calculation are constructed by tomography scanning. These models are used to set up a finite-element model for calculating the sound field distribution by loading the unit sound source in the glottis. By changing ... περισσότερα »
Speech rate and pitch characteristics of infant-directed speech: Longitudinal and cross-linguistic observations
Speech rate and pitch characteristics of infant-directed speech: Longitudinal and cross-linguistic observations: [image: cm_sbs_024_plain.png] The speech rate and pitch (F0) characteristics of naturalistic, longitudinally recorded infant- and adult-directed speech are reported for three, genetically diverse languages. Previous research has suggested that the prosodic characteristics of infant-directed speech are slowed speech rate, raised mean pitch, and expanded pitch range relative to adult-directed speech. Sixteen mothers (5 Sri Lankan Tamil, 5 Tagalog, 6 Korean) were recorded ... περισσότερα »
Tinnitus
Is Tinnitus Treatable?: What Is Tinnitus? Tinnitus is a condition where a person frequently experiences buzzing, hissing or ringing in the ears. It affects around 25 million people in America. There are several things that can trigger tinnitus, including noise-induced hearing loss, brain tumors, blood vessel damage or hormonal changes. It is also important to note that tinnitus can be a side effect of certain medications. In fact, it is estimated there are over 200 medications that can cause tinnitus. Is Tinnitus Treatable? Many people are wondering, “Is Tinnitus Treatable?” The... περισσότερα »
Phoneme and Word Scoring in Speech-in-Noise Audiometry
Phoneme and Word Scoring in Speech-in-Noise Audiometry: Purpose Understanding speech in background noise is difficult for many individuals; however, time constraints have limited its inclusion in the clinical audiology assessment battery. Phoneme scoring of words has been suggested as a method of reducing test time and variability. The purposes of this study were to establish a phoneme scoring rubric and use it in testing phoneme and word perception in noise in older individuals and individuals with hearing impairment. Method Words were presented to 3 participant groups at 80 dB i... περισσότερα »
Linguistic Masking Release in School-Age Children and Adults
Linguistic Masking Release in School-Age Children and Adults: Purpose This study assessed if 6- to 8-year-old children benefit from a language mismatch between target and masker speech for sentence recognition in a 2-talker masker. Method English sentence recognition was evaluated for English monolingual children (ages 6–8 years, n = 15) and adults (n = 15) in an English 2-talker and a Spanish 2-talker masker. A regression analysis with subject as a random variable was used to test the fixed effect of listener group and masker language and the interaction of these two effects. R... περισσότερα »
Relating Hearing Aid Use to Social and Emotional Loneliness in Older Adults
Relating Hearing Aid Use to Social and Emotional Loneliness in Older Adults: Purpose Hearing loss is a risk factor for social isolation and loneliness. We investigated the buffering effects of hearing aid use on perceived social and emotional loneliness. Method Forty older adults participated. Prior to and following the hearing aid fitting, participants completed the De Jong Gierveld Loneliness Scale (De Jong Gierveld & Kamphuis, 1985); a change in feelings of loneliness following hearing aid use was the outcome indicator. Results There was a significant decline in perceptions o... περισσότερα »
Validation of the Chinese Translation of the Spatial Hearing Questionnaire and Its Short Form
Validation of the Chinese Translation of the Spatial Hearing Questionnaire and Its Short Form: Purpose Few questionnaires address how to measure spatial hearing ability in complex listening situations. The purpose of the study was (a) to validate the Chinese translation of the Spatial Hearing Questionnaire (C-SHQ) among Chinese participants and (b) to provide a shortened version for the purpose of clinical screening. Method This was a cross-sectional study. The C-SHQ was developed from the process of translation and back-translation of the original 24-item, English version (Tyler... περισσότερα »
Outcomes of an International Audiology Service-Learning Study-Abroad Program
Outcomes of an International Audiology Service-Learning Study-Abroad Program: Purpose The purpose of this study was to evaluate students' academic and civic learning, with particular interest in cultural competence, gained through participation in the Speech, Language, and Hearing Sciences in Zambia study-abroad program. Method Twelve female students participated in the program. Quantitative data collected included pre- and postprogram administration of the Public Affairs Scale (Levesque-Bristol & Cornelius-White, 2012) to measure changes in participants' civic learning. Qualitat... περισσότερα »
Aided Electrophysiology Using Direct Audio Input: Effects of Amplification and Absolute Signal Level
Aided Electrophysiology Using Direct Audio Input: Effects of Amplification and Absolute Signal Level: Purpose This study investigated (a) the effect of amplification on cortical auditory evoked potentials (CAEPs) at different signal levels when signal-to-noise ratios (SNRs) were equated between unaided and aided conditions, and (b) the effect of absolute signal level on aided CAEPs when SNR was held constant. Method CAEPs were recorded from 13 young adults with normal hearing. A 1000-Hz pure tone was presented in unaided and aided conditions with a linear analog hearing aid. Dire... περισσότερα »
40-Hz Sinusoidal Auditory Steady-State Response and Tone Burst Auditory Brainstem Response Using a Kalman Filter to Determine Thresholds Pre- and Post-Myringotomy With Grommet Tube in Children With Mild, Low-Frequency Conductive Hearing Loss
40-Hz Sinusoidal Auditory Steady-State Response and Tone Burst Auditory Brainstem Response Using a Kalman Filter to Determine Thresholds Pre- and Post-Myringotomy With Grommet Tube in Children With Mild, Low-Frequency Conductive Hearing Loss: Purpose Accurate estimation of mild, low-frequency hearing loss is difficult in young children. This study aimed to determine the accuracy of 40-Hz sinusoidal auditory steady-state response (sASSR) compared with tone burst auditory brainstem response (TB-ABR) to detect mild, low-frequency hearing loss in children with otitis media with effusio...περισσότερα »
The Effect of Stimulus Intensity and Carrier Frequency on Auditory Middle- and Long-Latency Evoked Potentials Using a Steady-State-Response Approach
The Effect of Stimulus Intensity and Carrier Frequency on Auditory Middle- and Long-Latency Evoked Potentials Using a Steady-State-Response Approach: Purpose The purpose of this study was to measure magnitude changes of auditory steady-state responses (ASSRs) and respective transient middle- and long-latency responses as a function of stimulus intensity and carrier frequency. The literature lacks clear consensus, including relationship to loudness. Method A cohort of 48 adults with normal hearing was examined from a companion study (Tlumak, Durrant, & Delgado, 2015) on effects of ... περισσότερα »
Pilot Study to Determine Biodistribution of MM-398 and Feasibility of Ferumoxytol as a Tumor Imaging Agent
Pilot Study to Determine Biodistribution of MM-398 and Feasibility of Ferumoxytol as a Tumor Imaging Agent: *Conditions*: Solid Tumors; ER/PR Positive Breast Cancer; Triple Negative Breast Cancer; Metastatic Breast Cancer With Active Brain Metastasis *Intervention*: Drug: Ferumoxytol followed by MM-398 *Sponsor*: Merrimack Pharmaceuticals ArmsAssigned Interventions Experimental: Pilot Phase: Ferumoxytol followed by MM-398 (CLOSED) Ferumoxytol 5 mg/kg IV at the rate of 1 mL/sec, given once on Day 1. MM-398 80 mg/m2 IV over 90 min on Days 1 and 15 of every 4 week cycle Dr...περισσότερα »
S-1 and Radiotherapy for Elderly Esophageal Cancer Patients
S-1 and Radiotherapy for Elderly Esophageal Cancer Patients: *Conditions*: Esophageal Cancer; S-1; Radiotherapy *Interventions*: Drug: S-1; Radiation: radiotherapy *Sponsor*: Zhejiang Provincial People’s Hospital ArmsAssigned Interventions Experimental: Radiotherapy and S-1 arm Radiotherapy will be delivered with a daily fraction of 1.8-2.0Gy to a total dose of 54-60Gy. Preplanned concurrent S-1 (80mg/m²/day) will be administered on Day 1 for 14 days, every 3 weeks. After CCRT, maintenance S-1 will be given up to four cycles. Drug: S-1 S-1 will be administered orally tw... περισσότερα »
Treatment and Prevention of Middle Ear Morbidity in Head and Neck Cancer Patients Following Radiotherapy
Treatment and Prevention of Middle Ear Morbidity in Head and Neck Cancer Patients Following Radiotherapy: *Conditions*: Otitis Media With Effusion; Chronic Otitis Media; Hearing Loss *Intervention*: Device: Otovent® *Sponsor*: Roskilde County Hospital To investigate the incidence of tuba dysfunction (TD) and middle ear (ME) morbidity after radiotherapy (RT) to the Head & Neck and test the effect of auto-inflation of the Eustachian tube (ET) on middle ear effusion with a special designed balloon (Otovent®) and thereby better hearing and ear related quality of life after ... περισσότερα »
Cervical Kinematics' Reliability: Zero Positioning Using a 3-D-bulls Eye Spirit Level
Cervical Kinematics' Reliability: Zero Positioning Using a 3-D-bulls Eye Spirit Level: *Conditions*: Kinematics; Reliability; Cervical *Interventions*: Other: Zebris CMS 70; Other: 3-D Bulls Eye Spirit Meter *Sponsor*: Goethe University The measurement of cervical spine range of motion (ROM) figures among the most common aspects of clinical diagnosis. Good reliability has been demonstrated for assessments using ultrasonic movement analysis systems, such as Zebris CMS 70 (Isny, Germany). However, in contrast to combined measurements of movement amplitudes (e.g., flexion... περισσότερα »
Prediagnostic Helicobacter pylori Antibodies and Colorectal Cancer Risk.GroEl serostatus was associated with colorectal cancer risk (OR, 1.32, 95% CI: 1.03–1.70), whereas CagM was associated with colon cancer risk only (OR, 1.35, 95% CI: 1.01–1.80
Prediagnostic Helicobacter pylori Antibodies and Colorectal Cancer Risk in an Elderly, Caucasian Population: Abstract Background Study results on overall seroprevalence of *Helicobacter pylori* and colorectal cancer risk have been inconsistent. However, one study found positive associations with antibodies to specific *H. pylori* proteins. To follow up on those findings, we assessed associations of 15 *H. pylori* specific proteins with colorectal cancer incidence in the prospective Cancer Prevention Study-II Nutrition Cohort. Materials and Methods Participants in this nested case–co...περισσότερα »
Effects of Helicobacter pylori Infection on the Expressions and Functional Activities of Human Duodenal Mucosal Bicarbonate Transport Proteins
Effects of Helicobacter pylori Infection on the Expressions and Functional Activities of Human Duodenal Mucosal Bicarbonate Transport Proteins: Abstract Background The mechanisms for *Helicobacter pylori* (*H. pylori*)-induced duodenal ulcerogenesis are not fully understood. In this study, we investigated the effects of *H. pylori* infection on the expressions and functional activities of human duodenal mucosal bicarbonate transport proteins and hope to further clarify the pathogenesis of *H. pylori*-associated duodenal ulcer. Materials and Methods The experiments were performed in ...περισσότερα »
Difference of antrochoanal polyp between children and adults
Difference of antrochoanal polyp between children and adults via International Journal of Pediatric Otorhinolaryngology Publication date: May 2016 *Source:*International Journal of Pediatric Otorhinolaryngology, Volume 84 Author(s): Dong Hoon Lee, Tae Mi Yoon, Joon Kyoo Lee, Sang Chul Lim ObjectiveThe purpose of this study was to review the clinical characteristics of the antrochoanal polyp (ACP) and to compare the differences between children and adults.Patients and methodsThis study was performed in 56 patients who underwent endoscopic surgery for ACP between 2004 and 2014. The study ... περισσότερα »
Exosomes Derived from Squamous Head and Neck Cancer Promote Cell Survival after Ionizing Radiation
Exosomes Derived from Squamous Head and Neck Cancer Promote Cell Survival after Ionizing Radiation: by Lisa Mutschelknaus, Carsten Peters, Klaudia Winkler, Ramesh Yentrapalli, Theresa Heider, Michael John Atkinson, Simone Moertl Exosomes are nanometer-sized extracellular vesicles that are believed to function as intercellular communicators. Here, we report that exosomes are able to modify the radiation response of the head and neck cancer cell lines BHY and FaDu. Exosomes were isolated from the conditioned medium of irradiated as well as non-irradiated head and neck cancer cells by... περισσότερα »
Subacute Necrotizing Sialadenitis
Subacute Necrotizing Sialadenitis: A Series of Three Cases and Literature Review: AbstractSubacute necrotizing sialadenitis (SANS) is an unusual inflammatory condition known to primarily affect the minor salivary glands of the palatal region. Patients usually present with a localized, often erythematous palatal swelling accompanied by an abrupt onset of pain. The disease usually resolves between 2 days and a week with few extrapalatal reports lasting longer than 1 week. We report a series of three cases of SANS involving the palate.
The anatomical catch-up growth of the cerebellum did not normalize its function because of the disturbance of neuronal circuits by the combined effect of hypothyroidism and functional disruption of the DUOX/DUOXA complex.
Aberrant Cerebellar Development in Mice Lacking Dual Oxidase Maturation Factors: Thyroid , Vol. 0, No. 0. Author information Izuki Amano,1 Yusuke Takatsuru,1 Syutaro Toya,1 Asahi Haijima,1 Toshiharu Iwasaki,1 Helmut Grasberger,2,3 Samuel Refetoff,2,4,5 and Noriyuki Koibuchi1 1Department of Integrative Physiology, Gunma University Graduate School of Medicine, Maebashi, Japan. 2Department of Medicine, The University of Chicago, Chicago, Illinois. 3Division of Gastroenterology, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan 4Department of Pediatrics, The U... περισσότερα »
Tongue volume in adults with skeletal Class III dentofacial deformities
Tongue volume in adults with skeletal Class III dentofacial deformities: Abstract BackgroundThe size of the tongue is implicated as an essential etiological factor in the development of malocclusions. The aim of our study was to assess tongue size in skeletal Class III (SCIII) patients in comparison to adults with normal occlusion, using three-dimensional (3D) ultrasound. MethodsThe SCIII group consisted of 54 subjects; 34 females and 20 males and the control group contained 36 subjects, 18 from each gender with Class I relationship. 3D ultrasound images of the tongues were acqu... περισσότερα »
Cervical lymph node metastasis in adenoid cystic carcinoma of oral cavity and oropharynx: A collective international review
Cervical lymph node metastasis in adenoid cystic carcinoma of oral cavity and oropharynx: A collective international review: The purpose of this study was to suggest general guidelines in the management of the N0 neck of oral cavity and oropharyngeal adenoid cystic carcinoma (AdCC) in order to improve the survival of these patients and/or reduce the risk of neck recurrences. The incidence of cervical node metastasis at diagnosis of head and neck AdCC is variable, and ranges between 3% and 16%. Metastasis to the cervical lymph nodes of intraoral and oropharyngeal AdCC varies from 2% t...περισσότερα »
Cancer treatment left teen so toxic she couldn’t hung her mum – Glasgow Evening Times
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Glasgow Evening Times Cancer treatment left teen so toxic she couldn’t hung her mum Glasgow Evening Times The schoolgirl, who lives in Catrine, was being treated for tonsillitis when doctors discovered a four-inch long lump in her neck in 2014. The lump was later removed along with half of her thyroid. A second surgery came […]
Comparative Evaluation of Nimesulide-Loaded Nanoparticles for Anticancer Activity Against Breast Cancer Cells
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Abstract Recent clinical and epidemiological researches have declared that non-steroidal anti-inflammatory agents may display as antineoplastic agents and indicate pro-apoptotic and antiproliferative effects on cancer cells. The major purpose of this research was to develop a novel poly(ethyleneglycol)-block-poly(ε-caprolactone) (PEG-b-PCL) nano-sized particles encapsulated with nimesulide (NMS), a selective COX-2 inhibitor, and to evaluate its anticancer activity […]
Polysaccharide Encrusted Multilayered Nano-Colloidal System of Andrographolide for Improved Hepatoprotection
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Abstract Andrographolide (AP), a phytoconstituent of Andrographis paniculata is reported as a potent hepatoprotective agent. However, utility of this molecule is restricted due to its low aqueous solubility, gastric instability and hence low bioavailability. It was aimed to formulate and characterize AP-loaded, natural biopolymer stabilized, multilayered nano-hydrocolloid delivery system. Nanoemulsion (NE) was formulated using layer-by-layer […]
FIVE YEARS AFTER: Fukushima thyroid cancer patients’ families join forces – Asahi Shimbun
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Asahi Shimbun FIVE YEARS AFTER: Fukushima thyroid cancer patients’ families join forces Asahi Shimbun Families of young thyroid cancer patients from Fukushima Prefecture diagnosed after the 3/11 disaster have formed a support group that also aims to pressure doctors and authorities for better policies. The 311 Thyroid Cancer Family Group hopes to share … from […]
The influence of professional competence on the inter- and intra-individual esthetic evaluation of implant-supported crowns in the anterior maxilla
Abstract Objectives Evaluation of the influence of professional competence on esthetic predictability of implant-supported crowns in the anterior maxilla and identification of objective factors allowing predictable planning for esthetic results. Materials and methods Sixty patients with 82 implants in the esthetic zone were included in this study. Width of keratinized mucosa, biotype, recessions, and papilla index according to Jemt as well as radiological bone loss were assessed. Study casts and photographs were obtained. Each patient as well as people with different level of ex... περισσότερα »
Bruxism and dental implant treatment complications: a retrospective comparative study of 98 bruxer patients and a matched group
Abstract Objectives To analyze the complications of dental implant treatment in a group of patients with bruxism in comparison with a matched group of non-bruxers. Material and methods Patients being diagnosed as bruxers were identified within a group of patients consecutively treated with implant-supported prostheses at one specialist clinic, based on the most recent listed sign and symptoms of bruxism according to the International Classification of Sleep Disorders. A diagnostic grading system of "possible," "probable," and "definite" sleep or awake bruxism was used, according ...περισσότερα »
The Effect of Stimulus Intensity and Carrier Frequency on Auditory Middle- and Long-Latency Evoked Potentials Using a Steady-State-Response Approach
Purpose The purpose of this study was to measure magnitude changes of auditory steady-state responses (ASSRs) and respective transient middle- and long-latency responses as a function of stimulus intensity and carrier frequency. The literature lacks clear consensus, including relationship to loudness. Method A cohort of 48 adults with normal hearing was examined from a companion study (Tlumak, Durrant, & Delgado, 2015) on effects of aging. ASSRs were elicited by repeated tone-burst stimuli presented at rates of 40 and 0.75 Hz at 3 frequencies and 5 levels of stimulus intensity. The ...περισσότερα »
40-Hz Sinusoidal Auditory Steady-State Response and Tone Burst Auditory Brainstem Response Using a Kalman Filter to Determine Thresholds Pre- and Post-Myringotomy With Grommet Tube in Children With Mild, Low-Frequency Conductive Hearing Loss
Purpose Accurate estimation of mild, low-frequency hearing loss is difficult in young children. This study aimed to determine the accuracy of 40-Hz sinusoidal auditory steady-state response (sASSR) compared with tone burst auditory brainstem response (TB-ABR) to detect mild, low-frequency hearing loss in children with otitis media with effusion and to measure postoperative thresholds. Methods Thresholds at 500 and 4000 Hz were measured behaviorally and electrophysiologically using TB-ABR and 40-Hz sASSR with a Kalman filter in 26 children with otitis media with effusion. Recording w...περισσότερα »
Aided Electrophysiology Using Direct Audio Input: Effects of Amplification and Absolute Signal Level
Purpose This study investigated (a) the effect of amplification on cortical auditory evoked potentials (CAEPs) at different signal levels when signal-to-noise ratios (SNRs) were equated between unaided and aided conditions, and (b) the effect of absolute signal level on aided CAEPs when SNR was held constant. Method CAEPs were recorded from 13 young adults with normal hearing. A 1000-Hz pure tone was presented in unaided and aided conditions with a linear analog hearing aid. Direct audio input was used, allowing recorded hearing aid noise floor to be added to unaided conditions to e... περισσότερα »
Outcomes of an International Audiology Service-Learning Study-Abroad Program
Purpose The purpose of this study was to evaluate students' academic and civic learning, with particular interest in cultural competence, gained through participation in the Speech, Language, and Hearing Sciences in Zambia study-abroad program. Method Twelve female students participated in the program. Quantitative data collected included pre- and postprogram administration of the Public Affairs Scale (Levesque-Bristol & Cornelius-White, 2012) to measure changes in participants' civic learning. Qualitative data included journals, end-of-program reflection papers, videos, and researc...περισσότερα »
Validation of the Chinese Translation of the Spatial Hearing Questionnaire and Its Short Form
Purpose Few questionnaires address how to measure spatial hearing ability in complex listening situations. The purpose of the study was (a) to validate the Chinese translation of the Spatial Hearing Questionnaire (C-SHQ) among Chinese participants and (b) to provide a shortened version for the purpose of clinical screening. Method This was a cross-sectional study. The C-SHQ was developed from the process of translation and back-translation of the original 24-item, English version (Tyler, Perreau, & Ji, 2009). The C-SHQ was administered to 146 patients at the Department of Otolaryngo...περισσότερα »
Relating Hearing Aid Use to Social and Emotional Loneliness in Older Adults
Purpose Hearing loss is a risk factor for social isolation and loneliness. We investigated the buffering effects of hearing aid use on perceived social and emotional loneliness. Method Forty older adults participated. Prior to and following the hearing aid fitting, participants completed the De Jong Gierveld Loneliness Scale (De Jong Gierveld & Kamphuis, 1985); a change in feelings of loneliness following hearing aid use was the outcome indicator. Results There was a significant decline in perceptions of loneliness following 4 to 6 weeks of hearing aid use. A dose effect emerged wit... περισσότερα »
Linguistic Masking Release in School-Age Children and Adults
Purpose This study assessed if 6- to 8-year-old children benefit from a language mismatch between target and masker speech for sentence recognition in a 2-talker masker. Method English sentence recognition was evaluated for English monolingual children (ages 6–8 years, n = 15) and adults (n = 15) in an English 2-talker and a Spanish 2-talker masker. A regression analysis with subject as a random variable was used to test the fixed effect of listener group and masker language and the interaction of these two effects. Results Thresholds were approximately 5 dB higher for children than...περισσότερα »
Aided Electrophysiology Using Direct Audio Input: Effects of Amplification and Absolute Signal Level
Purpose This study investigated (a) the effect of amplification on cortical auditory evoked potentials (CAEPs) at different signal levels when signal-to-noise ratios (SNRs) were equated between unaided and aided conditions, and (b) the effect of absolute signal level on aided CAEPs when SNR was held constant. Method CAEPs were recorded from 13 young adults with normal hearing. A 1000-Hz pure tone was presented in unaided and aided conditions with a linear analog hearing aid. Direct audio input was used, allowing recorded hearing aid noise floor to be added to unaided conditions to e... περισσότερα »
Outcomes of an International Audiology Service-Learning Study-Abroad Program
Purpose The purpose of this study was to evaluate students' academic and civic learning, with particular interest in cultural competence, gained through participation in the Speech, Language, and Hearing Sciences in Zambia study-abroad program. Method Twelve female students participated in the program. Quantitative data collected included pre- and postprogram administration of the Public Affairs Scale (Levesque-Bristol & Cornelius-White, 2012) to measure changes in participants' civic learning. Qualitative data included journals, end-of-program reflection papers, videos, and researc...περισσότερα »
Validation of the Chinese Translation of the Spatial Hearing Questionnaire and Its Short Form
Purpose Few questionnaires address how to measure spatial hearing ability in complex listening situations. The purpose of the study was (a) to validate the Chinese translation of the Spatial Hearing Questionnaire (C-SHQ) among Chinese participants and (b) to provide a shortened version for the purpose of clinical screening. Method This was a cross-sectional study. The C-SHQ was developed from the process of translation and back-translation of the original 24-item, English version (Tyler, Perreau, & Ji, 2009). The C-SHQ was administered to 146 patients at the Department of Otolaryngo...περισσότερα »
Phoneme and Word Scoring in Speech-in-Noise Audiometry
Purpose Understanding speech in background noise is difficult for many individuals; however, time constraints have limited its inclusion in the clinical audiology assessment battery. Phoneme scoring of words has been suggested as a method of reducing test time and variability. The purposes of this study were to establish a phoneme scoring rubric and use it in testing phoneme and word perception in noise in older individuals and individuals with hearing impairment. Method Words were presented to 3 participant groups at 80 dB in speech-shaped noise at 7 signal-to-noise ratios (−10 to ... περισσότερα »
Linguistic Masking Release in School-Age Children and Adults
Purpose This study assessed if 6- to 8-year-old children benefit from a language mismatch between target and masker speech for sentence recognition in a 2-talker masker. Method English sentence recognition was evaluated for English monolingual children (ages 6–8 years, n = 15) and adults (n = 15) in an English 2-talker and a Spanish 2-talker masker. A regression analysis with subject as a random variable was used to test the fixed effect of listener group and masker language and the interaction of these two effects. Results Thresholds were approximately 5 dB higher for children than...περισσότερα »
The Effect of Stimulus Intensity and Carrier Frequency on Auditory Middle- and Long-Latency Evoked Potentials Using a Steady-State-Response Approach
Purpose The purpose of this study was to measure magnitude changes of auditory steady-state responses (ASSRs) and respective transient middle- and long-latency responses as a function of stimulus intensity and carrier frequency. The literature lacks clear consensus, including relationship to loudness. Method A cohort of 48 adults with normal hearing was examined from a companion study (Tlumak, Durrant, & Delgado, 2015) on effects of aging. ASSRs were elicited by repeated tone-burst stimuli presented at rates of 40 and 0.75 Hz at 3 frequencies and 5 levels of stimulus intensity. The ...περισσότερα »
40-Hz Sinusoidal Auditory Steady-State Response and Tone Burst Auditory Brainstem Response Using a Kalman Filter to Determine Thresholds Pre- and Post-Myringotomy With Grommet Tube in Children With Mild, Low-Frequency Conductive Hearing Loss
Purpose Accurate estimation of mild, low-frequency hearing loss is difficult in young children. This study aimed to determine the accuracy of 40-Hz sinusoidal auditory steady-state response (sASSR) compared with tone burst auditory brainstem response (TB-ABR) to detect mild, low-frequency hearing loss in children with otitis media with effusion and to measure postoperative thresholds. Methods Thresholds at 500 and 4000 Hz were measured behaviorally and electrophysiologically using TB-ABR and 40-Hz sASSR with a Kalman filter in 26 children with otitis media with effusion. Recording w...περισσότερα »
Aided Electrophysiology Using Direct Audio Input: Effects of Amplification and Absolute Signal Level
Purpose This study investigated (a) the effect of amplification on cortical auditory evoked potentials (CAEPs) at different signal levels when signal-to-noise ratios (SNRs) were equated between unaided and aided conditions, and (b) the effect of absolute signal level on aided CAEPs when SNR was held constant. Method CAEPs were recorded from 13 young adults with normal hearing. A 1000-Hz pure tone was presented in unaided and aided conditions with a linear analog hearing aid. Direct audio input was used, allowing recorded hearing aid noise floor to be added to unaided conditions to e... περισσότερα »
Outcomes of an International Audiology Service-Learning Study-Abroad Program
Purpose The purpose of this study was to evaluate students' academic and civic learning, with particular interest in cultural competence, gained through participation in the Speech, Language, and Hearing Sciences in Zambia study-abroad program. Method Twelve female students participated in the program. Quantitative data collected included pre- and postprogram administration of the Public Affairs Scale (Levesque-Bristol & Cornelius-White, 2012) to measure changes in participants' civic learning. Qualitative data included journals, end-of-program reflection papers, videos, and researc...περισσότερα »
Validation of the Chinese Translation of the Spatial Hearing Questionnaire and Its Short Form
Purpose Few questionnaires address how to measure spatial hearing ability in complex listening situations. The purpose of the study was (a) to validate the Chinese translation of the Spatial Hearing Questionnaire (C-SHQ) among Chinese participants and (b) to provide a shortened version for the purpose of clinical screening. Method This was a cross-sectional study. The C-SHQ was developed from the process of translation and back-translation of the original 24-item, English version (Tyler, Perreau, & Ji, 2009). The C-SHQ was administered to 146 patients at the Department of Otolaryngo...περισσότερα »
Relating Hearing Aid Use to Social and Emotional Loneliness in Older Adults
Purpose Hearing loss is a risk factor for social isolation and loneliness. We investigated the buffering effects of hearing aid use on perceived social and emotional loneliness. Method Forty older adults participated. Prior to and following the hearing aid fitting, participants completed the De Jong Gierveld Loneliness Scale (De Jong Gierveld & Kamphuis, 1985); a change in feelings of loneliness following hearing aid use was the outcome indicator. Results There was a significant decline in perceptions of loneliness following 4 to 6 weeks of hearing aid use. A dose effect emerged wit... περισσότερα »
Linguistic Masking Release in School-Age Children and Adults
Purpose This study assessed if 6- to 8-year-old children benefit from a language mismatch between target and masker speech for sentence recognition in a 2-talker masker. Method English sentence recognition was evaluated for English monolingual children (ages 6–8 years, n = 15) and adults (n = 15) in an English 2-talker and a Spanish 2-talker masker. A regression analysis with subject as a random variable was used to test the fixed effect of listener group and masker language and the interaction of these two effects. Results Thresholds were approximately 5 dB higher for children than...περισσότερα »
Phoneme and Word Scoring in Speech-in-Noise Audiometry
Purpose Understanding speech in background noise is difficult for many individuals; however, time constraints have limited its inclusion in the clinical audiology assessment battery. Phoneme scoring of words has been suggested as a method of reducing test time and variability. The purposes of this study were to establish a phoneme scoring rubric and use it in testing phoneme and word perception in noise in older individuals and individuals with hearing impairment. Method Words were presented to 3 participant groups at 80 dB in speech-shaped noise at 7 signal-to-noise ratios (−10 to ... περισσότερα »
Xanthogranuloma in the heavily irradiated low neck in a patient with head and neck cancer
Alexandros G. SfakianakisστοHead,Neck,Brain,Cervical Spine and Esophageal Cancers by Alexandros G. SfakianakisΠριν από 1 ώρα
[image: s40463-016-0134-6-1.gif] Background: Head and neck cancer is often managed with a combination of surgery, radiation therapy, and chemotherapy, and skin toxicity is not uncommon. Xanthogranuloma is a pathological finding resulting from an inflammatory reaction that has not been previously reported following head and neck radiation therapy.Case presentationA patient with squamous cell carcinoma of the oropharynx, treated with definitive chemoradiation and hyperthermia, presented at eight-month follow-up with an in-field cutaneous lesion in the low neck, initially concerning f... περισσότερα »
FIVE YEARS AFTER: Fukushima thyroid cancer patients’ families join forces – Asahi Shimbun
Asahi Shimbun FIVE YEARS AFTER: Fukushima thyroid cancer patients’ families join forces Asahi Shimbun Families of young thyroid cancer patients from Fukushima Prefecture diagnosed after the 3/11 disaster have formed a support group that also aims to pressure doctors and authorities for better policies. The 311 Thyroid Cancer Family Group hopes to share … from… Continue reading FIVE YEARS AFTER: Fukushima thyroid cancer patients’ families join forces – Asahi Shimbun
Scientism in the language sciences
Publication date: May 2016 Source:Language & Communication, Volume 48 Author(s): Jon Orman The article identifies two broad strands of scientism in modern linguistic thought. The first is that of mainstream linguistics which consists in the unwarranted scientisation of a culture-specific, second order metalinguistic discourse. The second, and the main focus of the paper, is that… Continue reading Scientism in the language sciences
The independence of syntactic processing in Mandarin: Evidence from structural priming
We report five experiments that used a structural priming paradigm to investigate the independence of syntactic processing in Mandarin. In a recognition memory task, Mandarin native speakers described ditransitive events after repeating prime sentences with a double object (DO) or prepositional object (PO) structure. Participants tended to repeat syntactic structure across prime and target sentences.… Continue reading The independence of syntactic processing in Mandarin: Evidence from structural priming
Same, different, or closely related: What is the relationship between language production and comprehension?
Publication date: Available online 22 March 2016 Source:Journal of Memory and Language Author(s): Antje S. Meyer, Falk Huettig, Willem J.M. Levelt (Source: Journal of Memory and Language) MedWorm Sponsor Message: Directory of the best January Sales in the UK. Find the best Christmas presents too. from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader… Continue reading Same, different, or closely related: What is the relationship between language production and comprehension?
Complex prosodic focus marking in Finnish: Expanding the data landscape
Publication date: May 2016 Source:Journal of Phonetics, Volume 56 Author(s): Anja Arnhold By investigating prosody beyond pitch and duration, this article provides a detailed and multifaceted picture of focus marking in a language that differs substantially from more extensively studied languages like English. A production study examined prosodic focus marking in Finnish based on acoustic… Continue reading Complex prosodic focus marking in Finnish: Expanding the data landscape
Use of outcome measurement by paediatric AHPs in Northern Ireland.
CONCLUSIONS & IMPLICATIONS: Clinicians would benefit from protected time and support from experts/role models to promote and facilitate best practice in the use of OM. Furthermore, funding for AHP services based on measurable outcomes for service users would facilitate their use in practice. Further research teasing out the different types of OM and the supports… Continue reading Use of outcome measurement by paediatric AHPs in Northern Ireland.
Do the early development of gestures and receptive and expressive language predict language skills at 5;0 in prematurely born very-low-birth-weight children?
Authors: Stolt S, Lind A, Matomäki J, Haataja L, Lapinleimu H, Lehtonen L Abstract It is unclear what the predictive value of very early development of gestures and language is on later language ability in prematurely born very-low-birth-weight (VLBW; birth weight ≤1500g) children. The aim of the present study was to analyse the predictive value… Continue reading Do the early development of gestures and receptive and expressive language predict language skills at 5;0 in prematurely born very-low-birth-weight children?
How Musicians Can Avoid Hearing Loss
Hearing loss is common amongst musicians and Eric Clapton, Pete Townshend, and Phil Collins are just a few musicians who have suffered with hearing loss over the years. The reason? The intensity of music is more than that of speech and this, consequently warrants different strategies and approaches to protect all musicians from hearing loss.… Continue reading How Musicians Can Avoid Hearing Loss
New Guideline for Survivors of Head-and-Neck Cancer – Managed Care magazine
Women’s eNews New Guideline for Survivors of Head-and-Neck Cancer Managed Care magazine A new guideline from the American Cancer Society (ACS) provides clinicians with recommendations on key areas of clinical follow-up care for survivors of head-and-neck cancer—a growing population numbering approximately 436,060 individuals and … ACS Now Has a Guideline for Care of Head and… Continue reading New Guideline for Survivors of Head-and-Neck Cancer – Managed Care magazine
Clinical spectrum of α-Gal syndrome: from immediate-type to delayed immediate-type reactions to mammalian innards and meat
Abstract The term α-Gal syndrome describes a novel IgE-mediated immediate-type allergy to the disaccharide galactose-α-1,3-galactose (α-Gal). Its classification as a syndrome is proposed on the basis of its clinical relevance in three different fields of allergy: food, drugs, and tick bites. The main focus of the present article is on α-Gal as an eliciting allergen… Continue reading Clinical spectrum of α-Gal syndrome: from immediate-type to delayed immediate-type reactions to mammalian innards and meat
Liberal MP diagnosed with cancer again – YorkRegion.com
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 2 ώρες
YorkRegion.com Liberal MP diagnosed with cancer again YorkRegion.com Shortly after winning his seat in a 2014 byelection, Chan was diagnosed with nasopharyngeal cancer that was centred in his sinuses and the lymph nodes in his shoulder. He endured six months of radiation and chemotherapy but felt healthy enough to run … from #AlexandrosSfakianakis via Alexandros […]
New World Paleoethnobotany in the New Millennium (2000–2013)
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 2 ώρες
Abstract This article evaluates the current state of paleoethnobotany since Hastorf’s 1999 review published in this journal. We discuss advances in methods, ancient subsistence reconstructions, the origins and intensification of agriculture, and how plants inform on issues of political economy and identity. Significant methodological developments in the extraction, identification, and analysis of starch grains and […]
Recognizing and Moving on from a Failed Paradigm: The Case of Agricultural Landscapes in Anglo-Saxon England c. AD 400–800
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 2 ώρες
Abstract A central preoccupation for archaeologists is how and why material culture changes. One of the most intractable examples of this problem can be found between AD 400 and 800 in the enigmatic transformation of sub-Roman into Anglo-Saxon England. That example lies at the heart of this review, explored through the case of the agricultural […]
Op GRITROCK ethics; the way of things to come?
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 2 ώρες
The Defence Medical Services (DMS) deployed on Op GRITROCK to Sierra Leone in support of the Ebola outbreak. This operation was the first large-scale DMS deployment since operations in Afghanistan ceased at the end of 2014. This type of operation revealed a number of ethical issues and challenges that the DMS had not faced for […]
Energy & Environment
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 2 ώρες
Energy & Environment, published by SAGE Publications, last updated on 2016-03-23, available at http://eae.sagepub.com from #AlexandrosSfakianakis via Alexandros G.Sfakianakis on Inoreader http://eae.sagepub.com/ via IFTTT
International Journal of Architectural Computing
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 2 ώρες
International Journal of Architectural Computing, published by SAGE Publications, last updated on 2016-03-23, available at http://jac.sagepub.com from #AlexandrosSfakianakis via Alexandros G.Sfakianakis on Inoreader http://jac.sagepub.com/ via IFTTT
Fecal Indicator Bacteria Dynamics in a Surface Flow Constructed Wetland in Southwestern Illinois, USA
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 2 ώρες
Abstract Constructed wetlands have been used to treat wastewater because of their efficiency at removing fecal indicator bacteria (FIB), their low cost, and their ease of maintenance. This study investigates the ability of a surface-flow wetland (0.03 ha in size), constructed in the rural village of Elsah, Illinois, to treat FIB pollution. The objectives of […]
Hepatitis E Virus Infection Among Solid Organ Transplant Recipients at a North American Transplant Center
sfakianakistherapeuticsστοTherapeutics Infections Emergencies MEDICINE BY ALEXANDROS G.SFAKIANAKIS,ANAPAFSEOS 5 AGIOS NIKOLAOS,CRETE 72100,GREECE,TEL :00302841026182 & 00306932607174Πριν από 2 ώρες
Background. Autochthonous hepatitis E virus (HEV) infection has been reported in over 200 solid organ transplant (SOT) recipients since 2006, yet little is known about the burden of HEV among SOT recipients in North America. We performed a retrospective, cross-sectional study to investigate the prevalence and risk factors associated with HEV infection among SOT recipients […]
Amalgam Removal Sydney – St Leonards Holistic Dental Care Safe Removal of Amagam Fillings
The post Amalgam Removal Sydney – St Leonards Holistic Dental Care Safe Removal of Amagam Fillings appeared first on Family Dentistry and Cosmetic Surgery Clinic. from #Dental via xlomafota13 on Inoreader http://ift.tt/1Mn8T1M via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
An Ecological Analysis of School Engagement Among Urban, Low-Income Latino Adolescents
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 2 ώρες
This study examined a multidimensional model of school engagement (Fredricks, Blumenfeld, & Paris, 2004) among low-income, urban Latino adolescents. Ecological theory suggests that students’ school, family, and peer contexts influence their behavioral, emotional, and cognitive engagement. Using qualitative methods of inquiry, this study examined how these various microsystemic factors influenced the school engagement of 32 […]
Sustainability and power in health promotion: community-based participatory research in a reproductive health policy case study in New Mexico
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 2 ώρες
Health promotion programs are commonly viewed as value-free initiatives which seek to improve health, often through behavior change. An opposing view has begun to emerge that health promotion efforts, especially ones seeking to impact health policy and social determinants of health, are vulnerable to political contexts and may depend on who is in power at […]
Resumes
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 2 ώρες
from #ORL-AlexandrosSfakianakis via simeraentaxei on Inoreader http://ift.tt/1Ub4qlu via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
The use of focus groups as a basis for planning and implementing culturally appropriate health promotion among people with diabetes in the Arab community
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 2 ώρες
Objective: The main study objective was to identify perceived barriers to achieving glycemic control among the Arab population in Israel, by both members of the Arab community with type 2 diabetes and by primary care teams working with the Arab community. Methods: A series of six focus groups using qualitative research methodology were conducted in […]
Key experiences of community engagement and social mobilization in the Ebola response
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 2 ώρες
The ongoing outbreak of the Ebola virus in West Africa is the largest on record; it has undermined already fragile healthcare systems and presented new challenges to contain the spread of the disease. Based on our observations in the field and insights from referenced sources, we aimed to identify key experiences of community engagement and […]
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