Influence of cochlear implantation on vestibular function.
*Influence of cochlear implantation on vestibular function.* Acta Otolaryngol. 2016 Mar 23;:1-5 Authors: Chen X, Chen X, Zhang F, Qin Z Abstract Conclusion Vestibular function in patients can be damaged following cochlear implantation. Therefore, assessing the pre-operative vestibular status, carefully choosing the side of implantation, and preserving function by using minimally invasive surgical techniques are important. Objectives The aim of this study was to assess the influence of cochlear implantation on vestibular function in patients with severe and profound sensorineural ... περισσότερα »
Vestibular evoked myogenic potentials (VEMPs): Tailoring methodology to specific conditions.
*Vestibular evoked myogenic potentials (VEMPs): Tailoring methodology to specific conditions.* Clin Neurophysiol. 2016 Mar 11; Authors: Papathanasiou ES PMID: 27005456 [PubMed - as supplied by publisher] from Head and Neck on PubMed via xlomafota13 on Inoreader http://ift.tt/1Pt82HE via IFTTT
Completely resected follicular dendritic cell sarcoma of the posterior mediastinum: report of a case.
*Completely resected follicular dendritic cell sarcoma of the posterior mediastinum: report of a case.* Surg Case Rep. 2016 Dec;2(1):28 Authors: Miyoshi R, Sonobe M, Miyamoto E, Date H Abstract Follicular dendritic cell sarcoma is a rare malignant neoplasm originating from follicular dendritic cells, and most of them develop in lymph nodes of the head and neck. One third of follicular dendritic cell sarcomas occur in the extranodal sites such as the tonsils, mesentery, and retroperitoneal organs, but those of mediastinal origin are rare. Here, we present the case of a 16-year-old... περισσότερα »
Endocranial Morphology of the Primitive Nodosaurid Dinosaur Pawpawsaurus campbelli from the Early Cretaceous of North America.
*Endocranial Morphology of the Primitive Nodosaurid Dinosaur Pawpawsaurus campbelli from the Early Cretaceous of North America.* PLoS One. 2016;11(3):e0150845 Authors: Paulina-Carabajal A, Lee YN, Jacobs LL Abstract BACKGROUND: Ankylosaurs are one of the least explored clades of dinosaurs regarding endocranial anatomy, with few available descriptions of braincase anatomy and even less information on brain and inner ear morphologies. The main goal of this study is to provide a detailed description of the braincase and internal structures of the Early Cretaceous nodosaurid Pawpawsa... περισσότερα »
Corrigendum.
*Corrigendum.* Cancer Biol Ther. 2016 Mar 3;17(3):336 Authors: PMID: 27007262 [PubMed - as supplied by publisher] from Head and Neck on PubMed via xlomafota13 on Inoreader http://ift.tt/1ZvROVQ via IFTTT
A Triad of Telomerase, Androgen Receptor and Early Growth Response 1 in Prostate Cancer Cells.
*A Triad of Telomerase, Androgen Receptor and Early Growth Response 1 in Prostate Cancer Cells.* Cancer Biol Ther. 2016 Mar 22;:0 Authors: Jacob S, Nayak S, Kakar R, Chaudhari UK, Joshi D, Vundinti BR, Fernandes G, Barai RS, Kholkute SD, Sachdeva G Abstract Telomerase activation is one of the key mechanisms that allow cells to bypass replicative senescence. Telomerase activity is primarily regulated at the level of transcription of its catalytic unit- hTERT. Prostate cancer (PCa), akin to other cancers, is characterized by high telomerase activity. Existing data suggest that hTER... περισσότερα »
Triptolide mitigates radiation-induced pulmonary fibrosis via inhibition of axis of alveolar macrophages-NOXes-ROS-myofibroblasts.
*Triptolide mitigates radiation-induced pulmonary fibrosis via inhibition of axis of alveolar macrophages-NOXes-ROS-myofibroblasts.* Cancer Biol Ther. 2016 Mar 22;:1-9 Authors: Chen C, Yang S, Zhang M, Zhang Z, Hong J, Han D, Ma J, Zhang SB, Okunieff P, Zhang L Abstract PURPOSE: IR-induced pulmonary fibrosis is one of the most severe late complications of radiotherapy for lung cancer. It is urgently needed to discover a new drug for anti-IR lung fibrosis. Our previous studies have indicated that TPL exhibits both anti-IR lung fibrosis and anti-tumor activities. To reveal the mech...περισσότερα »
Fibrodysplasia ossificans progressiva: initial presentation with a preosseous lesion of the scalp and its MRI appearance.
*Fibrodysplasia ossificans progressiva: initial presentation with a preosseous lesion of the scalp and its MRI appearance.* Skeletal Radiol. 2016 Mar 22; Authors: Lin FY, Lin CH, Shu G, Chen CK Abstract This case subject is a 1-year-old girl presenting with recurrent diffuse soft-tissue swelling of the scalp and periorbital region. Her family denied any known history of trauma. There was no obvious discoloration or local heat at the lesion. Magnetic resonance imaging (MRI) revealed diffuse soft tissue swelling of the scalp manifesting as high signal intensity on T2-weighted image... περισσότερα »
Reconsidering the benefit of intermittent versus continuous treatment in the maintenance treatment setting of metastatic colorectal cancer.
*Reconsidering the benefit of intermittent versus continuous treatment in the maintenance treatment setting of metastatic colorectal cancer.* Cancer Treat Rev. 2016 Mar 14;45:97-104 Authors: Sunakawa Y, Bekaii-Saab T, Stintzing S Abstract Colorectal cancer is one of the most frequent solid tumors in the western world, with low survival rates in patients with metastatic disease. Doublet chemotherapy regimens such as FOLFOX or FOLFIRI are the mainstay of standard first-line chemotherapy in the metastatic setting. The conventional treatment as a first-line approach is continuous appl...περισσότερα »
macrophage; +89 new citations
89 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: *macrophage* These pubmed results were generated on 2016/03/24 PubMed comprises more than 24 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites. from Head and Neck on PubMed via xlomafota13 on Inoreader http://ift.tt/1pzUTHE via IFTTT
Assessing perioperative complications associated with use of intraoperative magnetic resonance imaging during glioma surgery - a single centre experience with 516 cases.
*Assessing perioperative complications associated with use of intraoperative magnetic resonance imaging during glioma surgery - a single centre experience with 516 cases.* Br J Neurosurg. 2016 Mar 23;:1-4 Authors: Ahmadi R, Campos B, Haux D, Rieke J, Beigel B, Unterberg A Abstract BACKGROUND: Intraoperative magnetic resonance imaging (io-MRI) improves the extent of glioma resection. Due to the magnetic field, patients have to be covered with sterile drape and are then transferred into an io-MRI chamber, where ferromagnetic anaesthesia monitors and machines must be kept at distanc... περισσότερα »
Extensive basal ganglia hematomas treated by local thrombolysis versus conservative management - a comparative retrospective analysis.
*Extensive basal ganglia hematomas treated by local thrombolysis versus conservative management - a comparative retrospective analysis.* Br J Neurosurg. 2016 Mar 23;:1-6 Authors: Xu F, Lian L, Liang Q, Zhu W, Liu X, Kang H, Zhang M, Wang F, Xue Z, Tang Z, Zhu S Abstract OBJECTIVES: Single-target puncture plus catheter insertion into the clot is a routine step in hematoma aspiration and local thrombolysis for spontaneous intracerebral haemorrhage (ICH). However, multiple-target puncture of this procedure may imply faster hematoma reduction for large-area ICH. We retrospectively ex...περισσότερα »
Heavy Pot Use Tied to Social, Money Troubles in Mid-Life
But one marijuana advocate believes people who already have problems may often turn to the drug Source: HealthDay Related MedlinePlus Page: Marijuana from #Medicine-Sfakianakis via simeraentaxei on Inoreader http://ift.tt/1T7x1Hs via IFTTT
The Effect of Food Avoidance in Adult Patients with Chronic Idiopathic Urticaria.
CONCLUSION: Although SPT still yielded a low sensitivity for the diagnosis of FIU, the present study showed a very good response by food avoidance in patients who were SPT positive. PMID: 27004300 [PubMed – in process] (Source: Journal of the Medical Association of Thailand = Chotmaihet thangphaet) from #Head and Neck by Sfakianakis via simeraentaxei… Continue reading The Effect of Food Avoidance in Adult Patients with Chronic Idiopathic Urticaria.
Study Finds No Heart Risk from SSRI Antidepressants
Prozac actually appeared to protect against heart attack, researchers say Source: HealthDay Related MedlinePlus Pages: Antidepressants, Heart Attack, Medicines from #Medicine-Sfakianakis via simeraentaxei on Inoreader http://ift.tt/1pzXVf1 via IFTTT
Discussion
DR J KELLY WRIGHT (Nashville, TN): ABO incompatibility was considered for years to be an insurmountable immunologic barrier to successful organ transplantation due to the ubiquitous presence of A and B antigens on epithelial and endothelial tissues and the concurrent presence of pre-formed anti-A and anti-B isohemagglutinins. Intermittent successes of ABO incompatible transplants in extreme… Continue reading Discussion
Microorganisms, Vol. 4, Pages 18: Fed-Batch Production of Bacterial Ghosts Using Dielectric Spectroscopy for Dynamic Process Control
The Bacterial Ghost (BG) platform technology evolved from a microbiological expression system incorporating the ϕX174 lysis gene E. E-lysis generates empty but structurally intact cell envelopes (BGs) from Gram-negative bacteria which have been suggested as candidate vaccines, immunotherapeutic agents or drug delivery vehicles. E-lysis is a highly dynamic and complex biological process that puts exceptional… Continue reading Microorganisms, Vol. 4, Pages 18: Fed-Batch Production of Bacterial Ghosts Using Dielectric Spectroscopy for Dynamic Process Control
TCR signaling by conventional CD4+ T cells is required for optimal maintenance of peripheral regulatory T cell numbers
Abstract To maintain immune tolerance, regulatory T cell (Treg) numbers must be closely indexed to the number of conventional T cells (Tconvs) so that an adequate Treg:Tconv ratio can be maintained. Two factors important in this process are the cytokine interleukin‐2 (IL‐2) and T cell receptor (TCR) stimulation by major histocompatibility complex class II (MHC‐II).… Continue reading TCR signaling by conventional CD4+ T cells is required for optimal maintenance of peripheral regulatory T cell numbers
Solar Radiation Received by Slopes Using COMS Imagery, a Physically Based Radiation Model, and GLOBE
This study mapped the solar radiation received by slopes for all of Korea, including areas that are not measured by ground station measurements, through using satellites and topographical data. When estimating insolation with satellite, we used a physical model to measure the amount of hourly based solar surface insolation. Furthermore, we also considered the effects… Continue reading Solar Radiation Received by Slopes Using COMS Imagery, a Physically Based Radiation Model, and GLOBE
Expansion of B-1a Cells with Germline Heavy Chain Sequence in Lupus Mice
Nichol E. Holodick, Leilani Zeumer, Thomas L. Rothstein, Laurence Morel (Source: Frontiers in Immunology) from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://ift.tt/1UOoEQO via IFTTT
Nasal cytology: practical aspects and clinical relevance
This article is protected by copyright. All rights reserved. (Source: Clinical and Experimental Allergy) from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://ift.tt/1RzvJiZ via IFTTT
PAX5 promotes pre-B cell proliferation by regulating the expression of pre-B cell receptor and its downstream signaling
Publication date: May 2016 Source:Molecular Immunology, Volume 73 Author(s): Kai Xue, Jiazhe Song, Yan Yang, Zhi Li, Chunhua Wu, Jinhua Jin, Wenzhe Li PAX5 is indispensable for the commitment of early lymphoid progenitors to the B cell lineage as well as for the development of B cells. Although previous studies have indicated that the Pax5-conditional-knockout… Continue reading PAX5 promotes pre-B cell proliferation by regulating the expression of pre-B cell receptor and its downstream signaling
Usefulness of the radiological planning for hearing preservation surgery in vestibular schwannoma
Usefulness of the radiological planning for hearing preservation surgery in vestibular schwannoma: Abstract PurposeDuring vestibular schwannoma surgery there is a risk of endolymphatic duct and sac injury, which may cause a loss or a deterioration of hearing. The goal of the study was to evaluate the empirical utility of presurgical planning using CT with the bone window for the hearing preservation surgery. MethodsThe study was performed on 14 human temporal bones. CT scans with the bone window were obtained in the standard position. Safe drilling line was evaluated and after... περισσότερα »
Peripheral T-cell lymphomas, not otherwise specified, of lymphoepithelioid variant (Lennert's lymphoma)
Clinicopathological analysis of a case series of peripheral T-cell lymphomas, not otherwise specified, of lymphoepithelioid variant (Lennert's lymphoma). A Central European single-center study—reply: We thank Dr. Gafencu and colleagues for their interest in our article [1]. We reported a case series of nodal EBV+ T/NK-cell lymphomas that were characterized by diffuse proliferation of atypical cells centroblastic in terms of morphology that expressed cytotoxic molecules, which were frequently of the CD8+αβT-cell lineage that exhibited predominantly nodal involvement of elderly patien... περισσότερα »
A Subset of Ectomesenchymal Chondromyxoid Tumors of the Tongue shows EWSR1 Rearrangements and is Genetically Linked to Soft Tissue Myoepithelial Neoplasms: A study of 11 cases
A Subset of Ectomesenchymal Chondromyxoid Tumors of the Tongue shows EWSR1 Rearrangements and is Genetically Linked to Soft Tissue Myoepithelial Neoplasms: A study of 11 cases: [image: cover.gif?v=1&s=30d36619adef656e092a2a88] Abstract Aims Ectomesenchymal chondromyxoid tumor (ECT) is a rare, benign intraoral neoplasm showing predilection for the anterior dorsum of the tongue. The World Health Organization (W.H.O.) includes ECT in the pathologic spectrum of soft tissue myoepithelioma. *EWSR1* rearrangement is identified in 45% of cutaneous, soft tissue and bone myoepithelial neo...περισσότερα »
Prothrombin Complex Concentrates for Bleeding in the Perioperative Setting.Prothrombin complex concentrates (PCCs) contain vitamin K-dependent clotting factors (II, VII, IX, and X) and are marketed as 3 or 4 factor-PCC formulations depending on the concentrations of factor VII.
Prothrombin Complex Concentrates for Bleeding in the Perioperative Setting.: Prothrombin complex concentrates (PCCs) contain vitamin K-dependent clotting factors (II, VII, IX, and X) and are marketed as 3 or 4 factor-PCC formulations depending on the concentrations of factor VII. PCCs rapidly restore deficient coagulation factor concentrations to achieve hemostasis, but like with all procoagulants, the effect is balanced against thromboembolic risk. The latter is dependent on both the dose of PCCs and the individual patient prothrombotic predisposition. PCCs are approved by the US F... περισσότερα »
Vibrent Smartphone Mobile Application
*Condition*: Mucositis *Intervention*: Other: Vibrogent Smartphone Application *Sponsor*: Sidney Kimmel Comprehensive Cancer Center *Recruiting* - verified March 2016 from #ORL-Sfakianakis via xlomafota13 on Inoreader http://ift.tt/1o8DJQe via IFTTT
Implantation of the Auditory Nerve via the Middle Ear Cavity in Rats with Partial Hearing Preservation
The aim of this study was to evaluate the residual hearing function and cochlear morphology after auditory nerve implantation via middle ear spaces in rats. A titanium rod (1.5 mm long and 0.3 mm thick) coated with Parylene was inserted in the cochlear apex in the direction of the modiolus in 9 Wistar rats. Auditory brainstem-evoked responses to tone bursts at 2, 8, 12 and 32 kHz were recorded before surgery and on postoperative days 0, 2, 15 and 30. Eight cochleas were examined microscopically. The rod was inside the modiolus in 4, and partly or totally outside the modiolus in 4 a... περισσότερα »
Long-term EEG in patients with the ring chromosome 20 epilepsy syndrome
[image: cover.gif?v=1&s=2e8a2d7e6f7aaaecf5823a36] Summary The recognizable electroencephalography (EEG) pattern of ring chromosome 20 epilepsy syndrome can be missing in patients with r(20) chromosomal anomaly, and may be found in patients with frontal lobe epilepsy of other origin. This study aims to search for more specific EEG signs by using long-term recordings and measuring the duration of paroxysmal anomalies. The series included 12 adult patients with r(20) anomaly, and 12 controls without any chromosomal aberration. We measured the duration of every paroxysmal burst and c... περισσότερα »
Passive immunization with HIV-1–neutralizing antibodies: Is it effective and safe?
Abstract Human immunodeficiency virus type 1 (HIV-1) infection, along with HIV-2 the cause of acquired immunodeficiency syndrome (AIDS), has been a global health problem for more than three decades (Sharp and Hahn 2011). A recent report from UNAIDS indicated that an estimated 35 million people were living with HIV-1 worldwide and 2.1 million became newly infected (UNAIDS, 2014). Antiretroviral therapy (ART) is a current treatment for HIV-1 infection (Hammer et al, 2008). ART can suppress HIV-1 replication and reduce the morbidity and mortality rate in HIV/AIDS patients. However, it... περισσότερα »
Volumes of Velopharyngeal and Glossopharyngeal Airway Were Not Changed after Uvulopalatopharyngoplasty: Report of Three Cases
Objective. The aim of this study was to investigate the changes in velopharyngeal and glossopharyngeal airway morphology and volume after uvulopalatopharyngoplasty in three adult obstructive sleep apnea syndrome patients who had bilateral large tonsils using three-dimensional computed tomography. Case Report. All three patients (one male and two females) who presented with a history of heavy snoring and excessive daytime sleepiness were examined with overnight nocturnal polysomnography, which indicated moderate-to-severe obstructive sleep apnea syndrome. Because all patients had l...περισσότερα »
Effect of the retinal size of a peripheral cue on attentional orienting in two- and three-dimensional worlds
Abstract It has been documented that due to limited attentional resources, the size of the attentional focus is inversely correlated with processing efficiency. Moreover, by adopting a variety of two-dimensional size illusions induced by pictorial depth cues (e.g., the Ponzo illusion), previous studies have revealed that the perceived, rather than the retinal, size of an object determines its detection. It remains unclear, however, whether and how the retinal versus perceived size of a cue influences the process of attentional orienting to subsequent targets, and whether the corre... περισσότερα »
Astrocytes Regulate GLP-1 Receptor-Mediated Effects on Energy Balance
Astrocytes are well established modulators of extracellular glutamate, but their direct influence on energy balance-relevant behaviors is largely understudied. As the anorectic effects of glucagon-like peptide-1 receptor (GLP-1R) agonists are partly mediated by central modulation of glutamatergic signaling, we tested the hypothesis that astrocytic GLP-1R signaling regulates energy balance in rats. Central or peripheral administration of a fluorophore-labeled GLP-1R agonist, exendin-4, localizes within astrocytes and neurons in the nucleus tractus solitarius (NTS), a hindbrain nucl... περισσότερα »
Propagating Neural Source Revealed by Doppler Shift of Population Spiking Frequency
Electrical activity in the brain during normal and abnormal function is associated with propagating waves of various speeds and directions. It is unclear how both fast and slow traveling waves with sometime opposite directions can coexist in the same neural tissue. By recording population spikes simultaneously throughout the unfolded rodent hippocampus with a penetrating microelectrode array, we have shown that fast and slow waves are causally related, so a slowly moving neural source generates fast-propagating waves at ~0.12 m/s. The source of the fast population spikes is limite... περισσότερα »
Opening Holes in the Blanket of Inhibition: Localized Lateral Disinhibition by VIP Interneurons
Inhibitory interneurons in the neocortex often connect in a promiscuous and extensive fashion, extending a "blanket of inhibition" on the circuit. This raises the problem of how can excitatory activity propagate in the midst of this widespread inhibition. One solution to this problem could be the vasoactive intestinal peptide (VIP) interneurons, which disinhibit other interneurons. To explore how VIP interneurons affect the local circuits, we use two-photon optogenetics to activate them individually in mouse visual cortex *in vivo* while measuring their output with two-photon calci... περισσότερα »
Effects of Optogenetic Activation of Corticothalamic Terminals in the Motor Thalamus of Awake Monkeys
The role of the corticothalamic projection in the ventral motor thalamus remains poorly understood. Therefore, we studied the electrophysiological responses of neurons in the basal ganglia and cerebellar receiving-territories of the motor thalamus (BGMT and CbMT, respectively) using optogenetic activation of corticothalamic projections in awake rhesus macaques. After injections of viral vectors carrying the excitatory opsins ChR2 or C1V1 into the primary motor and premotor cortices of two monkeys, we used optrodes to light activate opsin-expressing neurons in cortex or their termi... περισσότερα »
Complex Multiplexing of Reward-Cue- and Licking-Movement-Related Activity in Single Midline Thalamus Neurons
Midline thalamus is implicated in linking visceral and exteroceptive sensory information with behavior. However, whether neuronal activity is modulated with temporal precision by cues and actions in real time is unknown. Using single-neuron recording and a Pavlovian visual-cue/liquid-reward association task in rats, we discovered phasic responses to sensory cues, appropriately timed to modify information processing in output targets, as well as tonic modulations within and between trials that were differentially reward modulated, which may have distinct arousal functions. Many of ... περισσότερα »
The Haider Tube-Guard significantly reduced the mobility of the endotracheal tube
A Comparison of the Haider Tube-Guard(R) Endotracheal Tube Holder Versus Adhesive Tape to Determine if This Novel Device Can Reduce Endotracheal Tube Movement and Prevent Unplanned Extubation.: BACKGROUND: Endotracheal tube security is a critical safety issue. We compared the mobility of an in situ endotracheal tube secured with adhesive tape to the one secured with a new commercially available purpose-designed endotracheal tube-holder device (Haider Tube-Guard(R)). We also observed for the incidence of oropharyngeal or facial trauma associated with the 2 tube fixation methods. METH... περισσότερα »
The Haider Tube-Guard(R) Endotracheal Tube Holder Versus Adhesive Tape to Determine if This Novel Device Can Reduce Endotracheal Tube Movement and Prevent Unplanned Extubation.
A Comparison of the Haider Tube-Guard(R) Endotracheal Tube Holder Versus Adhesive Tape to Determine if This Novel Device Can Reduce Endotracheal Tube Movement and Prevent Unplanned Extubation.: BACKGROUND: Endotracheal tube security is a critical safety issue. We compared the mobility of an in situ endotracheal tube secured with adhesive tape to the one secured with a new commercially available purpose-designed endotracheal tube-holder device (Haider Tube-Guard(R)). We also observed for the incidence of oropharyngeal or facial trauma associated with the 2 tube fixation methods. METH... περισσότερα »
Dexmedetomidine premedication with three different dosages to attenuate the adverse hemodynamic responses of direct laryngoscopy and intubation: a comparative evaluation
Dexmedetomidine premedication with three different dosages to attenuate the adverse hemodynamic responses of direct laryngoscopy and intubation: a comparative evaluation: *Kumkum Gupta, Manoranjan Bansal, Prashant K Gupta, Meetu Singh, Shikha Agarwal, Vaibhav Tiwari* Ain-Shams Journal of Anaesthesiology 2016 9(1):66-71 Background Direct laryngoscopy and tracheal intubation predictably lead to transient and variable hemodynamic responses, which can be attenuated by α2-receptor agonists. The present study aimed to evaluate comparatively the three different dosages of dexmedetomid... περισσότερα »
A new protocol for dexmedetomidine administration
Controlled hypotensive anesthesia for functional endoscopic sinus surgery: a new protocol for dexmedetomidine administration: *Ayman A Rayan* Ain-Shams Journal of Anaesthesiology 2016 9(1):57-65 Objective The aim of the study was to conduct a comparative investigation to evaluate the efficacy of dexmedetomidine as a hypotensive agent by presenting a new protocol for administration versus the conventional protocol in functional endoscopic sinus surgery (FESS). Materials and methods Forty patients of ASA grade I-II scheduled for FESS were equally randomly assigned to two groups:... περισσότερα »
Controlled hypotensive anesthesia for functional endoscopic sinus surgery
: a new protocol for dexmedetomidine administration: *Ayman A Rayan* Ain-Shams Journal of Anaesthesiology 2016 9(1):57-65 Objective The aim of the study was to conduct a comparative investigation to evaluate the efficacy of dexmedetomidine as a hypotensive agent by presenting a new protocol for administration versus the conventional protocol in functional endoscopic sinus surgery (FESS). Materials and methods Forty patients of ASA grade I-II scheduled for FESS were equally randomly assigned to two groups: the DEX group and the DEXnew group. The DEX group received dexmedetomidi... περισσότερα »
Correlation between central venous and peripheral venous pressures in surgical patients
Correlation between central venous and peripheral venous pressures in surgical patients: *Rajan Sunil, Nadarajan Vishnu, Kumar Lakshmi* Ain-Shams Journal of Anaesthesiology 2016 9(1):52-56 Introduction The central venous pressure (CVP) measurement is important in assessing right ventricular function and systemic fluid status, and the venous pressures measured from peripheral venous catheters closely correlate with CVP and/or CVP trends. The correlation between CVP and peripheral venous pressure (PVP) in patients undergoing major surgical procedures under mechanical ventilation ...περισσότερα »
Does nebulized dexamethasone decrease the incidence of postextubation sore throat?: a randomized controlled study
Does nebulized dexamethasone decrease the incidence of postextubation sore throat?: a randomized controlled study: *Atef K Salama, Ahmed M El-badawy* Ain-Shams Journal of Anaesthesiology 2016 9(1):104-107 Objective and aim of study Postoperative sore throat (POST) is a common complaint in about 21-65% of patients undergoing general anesthesia with endotracheal intubation. The aim of this randomized controlled study was to evaluate the efficacy of preoperative nebulized dexamethasone in decreasing the incidence of postextubation sore throat. Patients and methods A total of 120 ...περισσότερα »
Desflurane has better hemodynamic parameters and recovery characteristics in comparison with isoflurane
Isoflurane versus desflurane: hemodynamic parameters and recovery characteristics: a comparative study: *Aktham A Shoukry, Ayman Abd Laltif, Amr Abd Fattah, Ibrahim Abd Ghani, Mohamed Serag* Ain-Shams Journal of Anaesthesiology 2016 9(1):45-51 Introduction Inhaled volatile anesthetics remain the most widely used drugs for maintenance of general anesthesia because of their ease of administration and predictable intraoperative and recovery characteristics. Management of hemodynamic stability and early recovery is the most important part of a standardized balanced technique. Given...περισσότερα »
Isoflurane versus desflurane: hemodynamic parameters and recovery characteristics: a comparative study
Isoflurane versus desflurane: hemodynamic parameters and recovery characteristics: a comparative study: *Aktham A Shoukry, Ayman Abd Laltif, Amr Abd Fattah, Ibrahim Abd Ghani, Mohamed Serag* Ain-Shams Journal of Anaesthesiology 2016 9(1):45-51 Introduction Inhaled volatile anesthetics remain the most widely used drugs for maintenance of general anesthesia because of their ease of administration and predictable intraoperative and recovery characteristics. Management of hemodynamic stability and early recovery is the most important part of a standardized balanced technique. Given...περισσότερα »
Induction of anesthesia and endotracheal intubation in children without muscle relaxant: a comparative study on addition of fentanyl or propofol to sevoflurane
Induction of anesthesia and endotracheal intubation in children without muscle relaxant: a comparative study on addition of fentanyl or propofol to sevoflurane: *Hazem M Fawzi, Ghada M Samir* Ain-Shams Journal of Anaesthesiology 2016 9(1):39-44 Background Intubation without the need of muscle relaxant is a common practice in pediatric patients. Many drugs are used with inhalational induction to improve the intubation score and to decrease the induction time; of these drugs are propofol and narcotics. The aim of this study was to compare the effect of adding propofol or fentanyl... περισσότερα »
Use of growth hormone in the treatment of pediatric burns
Use of growth hormone in the treatment of pediatric burns: *Yasser A Salem* Ain-Shams Journal of Anaesthesiology 2016 9(1):1-5 Hypermetabolic response is characterized by a hyperdynamic circulatory response, with increased body temperature; increased oxygen and glucose consumption; increased carbon dioxide production; hyperglycemia (raised blood sugar levels); peripheral insulin resistance; glycogenolysis, proteolysis, and lipolysis (i.e. the breakdown of glycogen, protein, and lipids, respectively); the loss of lean body mass; and muscle and bone wasting. These symptoms can las...περισσότερα »
Hemodynamic response to tracheal intubation with laryngoscope versus intubating laryngeal mask airway in elderly hypertensive patients
Comparison of hemodynamic response to tracheal intubation with laryngoscope versus intubating laryngeal mask airway in elderly hypertensive patients: *Mohamed M Abdel Fattah* Ain-Shams Journal of Anaesthesiology 2016 9(1):34-38 Background Management of airways during intubation is a very stressful process that affects the hemodynamics, especially in elderly hypertensive patients. We aimed in this study to compare the hemodynamic response to tracheal intubation in elderly hypertensive patients using ILMA and Direct laryngoscopy. We aim in this study to prove that hemodynamic co...περισσότερα »
Venous oxygen embolism after inadvertent subcutaneous injection of hydrogen peroxide
Venous oxygen embolism after inadvertent subcutaneous injection of hydrogen peroxide: *Kundan S Gosavi, Surbhi D Mundada, Senthil K Praveen Kumar* Ain-Shams Journal of Anaesthesiology 2016 9(1):139-141 The hazards of hydrogen peroxide have been known for long time, but it is still widely used in our country for irrigation of wounds. We report a case of oxygen embolism when hydrogen peroxide was accidently infiltrated subcutaneously along with local anesthetic during spine surgery and was successfully managed. We discuss the possible mechanism for embolism and its management. We ... περισσότερα »
Fiberoptic bronchoscopes and intubating laryngeal masks
Airway management for morbidly obese patients: a comparative study between fiberoptic bronchoscopes and intubating laryngeal masks: *Hala M.S. Eldeen, Aboelnour Elmorsy Badran, Mona A Hashish, Doaa G Diab* Ain-Shams Journal of Anaesthesiology 2016 9(1):27-33 Background Obesity is an epidemic disease that continues to increase in most countries. It is estimated that more than 30% of the adult population is obese. Airway management in morbidly obese adults may be a challenge to anesthesiologists due to anatomical and physiological changes that affect obese patients. The intubatin...περισσότερα »
Airway management for morbidly obese patients
Airway management for morbidly obese patients: a comparative study between fiberoptic bronchoscopes and intubating laryngeal masks: *Hala M.S. Eldeen, Aboelnour Elmorsy Badran, Mona A Hashish, Doaa G Diab* Ain-Shams Journal of Anaesthesiology 2016 9(1):27-33 Background Obesity is an epidemic disease that continues to increase in most countries. It is estimated that more than 30% of the adult population is obese. Airway management in morbidly obese adults may be a challenge to anesthesiologists due to anatomical and physiological changes that affect obese patients. The intubatin...περισσότερα »
Unique cardiac injury after high-voltage electrical burn
Unique cardiac injury after high-voltage electrical burn: *Yasser A Salem, Rania Hassan* Ain-Shams Journal of Anaesthesiology 2016 9(1):122-125 Patients of high-voltage injury commonly present with devastating burns requiring prolonged hospitalization with multiple complications. Crossing of sufficient current flow through cardiac tissue can cause lethal arrhythmia. This may lead to immediate cardiac arrest. In the following case report we described a condition of probable anatomic disfigurement of the endocardium and intracardiac structures secondary to high-voltage electrical...περισσότερα »
Effect of lidocaine instillation into endotracheal tube on intraocular pressure during extubation
Effect of lidocaine instillation into endotracheal tube on intraocular pressure during extubation: *Ahmed Hassanein, Josef Zekry, Hosam Moharram* Ain-Shams Journal of Anaesthesiology 2016 9(1):23-26 Objectives The aim of this study was to investigate the effect of lidocaine instillation into the endotracheal tube before extubation on intraocular pressure (IOP) and hemodynamics. Patients and methods A total of 60 patients of ASA physical status I and II between 18 and 40 years of age who were scheduled for elective unilateral ocular surgery (cataract, squint, or ptosis) were in... περισσότερα »
Laryngoscopy and intubation : Effect of nitrous oxide inhalation on induction dose of propofol, induction time, oxygen saturation, and hemodynamic responses to laryngoscopy and intubation
Effect of nitrous oxide inhalation on induction dose of propofol, induction time, oxygen saturation, and hemodynamic responses to laryngoscopy and intubation: *Rajan Sunil, Sarath Vijayakrishna Pillai, Kumar Lakshmi* Ain-Shams Journal of Anaesthesiology 2016 9(1):99-103 Context Nitrous oxide enhances the anesthetic potential of other agents and thereby reduces their requirement. Aims This study aimed to determine the effect of nitrous oxide inhalation on the induction dose of propofol, induction time, oxygen saturation, and hemodynamic responses to laryngoscopy and intubation.... περισσότερα »
Sedation therapy using midazolam or propofol continuous infusion in patients with severe traumatic brain injury
Outcome of sedation therapy using midazolam or propofol continuous infusion in patients with severe traumatic brain injury: *Mohamed Amr Shabana* Ain-Shams Journal of Anaesthesiology 2016 9(1):108-115 Objectives The aim of this study was to compare the sedative effect of midazolam and propofol alone or in combination on hemodynamic stability and subsequent intracranial pressure (ICP) changes in adults with severe traumatic brain injury. Patients and methods All patients received fentanyl continuous infusion and were randomly divided into three groups: group I received midazola... περισσότερα »
Paediatric procedural sedation using ketamine in a emergency department
Paediatric procedural sedation using ketamine in a UK emergency department: a 7 year review of practice: Background Ketamine is growing in popularity for procedural sedation in the paediatric population, yet safety concerns remain. We performed a retrospective review of practice and outcomes of paediatric ketamine sedation using the World SIVA International Sedation Task Force reporting tool. Methods A retrospective inspection of the dedicated emergency department electronic sedation database and subsequent note and sedation chart review was performed for all paediatric sedations t... περισσότερα »
Cardio-protective effects of desflurane and sevoflurane
The mechanisms of cardio-protective effects of desflurane and sevoflurane at the time of reperfusion: anaesthetic post-conditioning potentially translatable to humans?: Myocardial conditioning is actually an essential strategy in the management of ischaemia-reperfusion injury. The concept of anaesthetic post-conditioning is intriguing, its action occurring at a pivotal moment (that of reperfusion when ischaemia reperfusion lesions are initiated) where the activation of these cardio-protective mechanisms could overpower the mechanisms leading to ischaemia reperfusion injuries. Desfl...περισσότερα »
High Glucose Attenuates Anesthetic Cardioprotection in Stem-Cell-Derived Cardiomyocytes: The Role of Reactive Oxygen Species and Mitochondrial Fission.
High Glucose Attenuates Anesthetic Cardioprotection in Stem-Cell-Derived Cardiomyocytes: The Role of Reactive Oxygen Species and Mitochondrial Fission.: BACKGROUND: Hyperglycemia can blunt the cardioprotective effects of isoflurane in the setting of ischemia-reperfusion injury. Previous studies suggest that reactive oxygen species (ROS) and increased mitochondrial fission play a role in cardiomyocyte death during ischemia-reperfusion injury. To investigate the role of glucose concentration in ROS production and mitochondrial fission during ischemia-reperfusion (with and without anes...περισσότερα »
Hyperoxic oxidative stress during surgery
Hyperoxic oxidative stress during abdominal surgery: a randomized trial: Abstract PurposeThe hypothesis of our study is that during anesthesia, administration of 80 % oxygen concentration increases oxidative stress more than 40 % oxygen. MethodsForty ASA I-II patients were included in a randomized, single-blind study. Expiratory tidal volumes (ETV) were measured before induction and after extubation. After ventilation with 0.8 FiO2 and intubation, mini-bronchoalveolar lavage (mini-BAL), arterial blood gas (ABG), and blood samples were taken. Patients were randomly assigned to r... περισσότερα »
Nasal cytology: practical aspects and clinical relevance
Nasal cytology: practical aspects and clinical relevance: Summary Nasal cytology is a simple and safe diagnostic procedure that allows to assess the normal and pathological aspects of the nasal mucosa, by identifying and counting the cell types and their morphology. It can be easily performed by a nasal scraping followed by May-Grunwald-Giemsa staining and optical microscopy reading. This procedure allows to identify the normal cells (ciliated and mucinous), the inflammatory cells (lymphocytes, neutrophils, eosinophils, mast cells), and bacteria or fungal ifae/spores. Apart from th... περισσότερα »
Microneedle-mediated intradermal delivery of epigallocatechin-3-gallate.Epigallocatechin-3-gallate (EGCG) is the physiologically most active and abundant flavanol, accounting for 50-80% of green tea catechins. It is an anti-inflammatory, anti-oxidant, chemopreventive and skin photoprotective agent.
Microneedle-mediated intradermal delivery of epigallocatechin-3-gallate: Abstract Objective Epigallocatechin-3-gallate (EGCG) is the physiologically most active and abundant flavanol, accounting for 50-80% of green tea catechins. It is an anti-inflammatory, anti-oxidant, chemopreventive and skin photoprotective agent. However, light sensitivity and low permeability of EGCG across the stratum corneum due to its high molecular weight as well as strong binding to the lipid bilayers in the skin makes it difficult to be used as a key ingredient in cosmetic products. The present study aim... περισσότερα »
Immunohistochemical expression of GLUT-1, GLUT-3, and carbonic anhydrase IX in benign odontogenic lesions
Immunohistochemical expression of GLUT-1, GLUT-3, and carbonic anhydrase IX in benign odontogenic lesions: [image: cover.gif?v=1&s=a0ff55faa388bf623a351a74] Background Some benign odontogenic lesions have a distinct biological behavior with high recurrence rates and local aggressive behavior. To determine whether glucose transporters proteins (GLUT-1 and GLUT-3) and carbonic anhydrase IX (CA IX) are associated with the development of as dentigerous cyst (DC), odontogenic keratocyst (OK), and ameloblastoma (AM), we evaluated the immunohistochemical expression of these proteins in... περισσότερα »
Passive immunization with HIV-1–neutralizing antibodies
: Is it effective and safe?: Abstract Human immunodeficiency virus type 1 (HIV-1) infection, along with HIV-2 the cause of acquired immunodeficiency syndrome (AIDS), has been a global health problem for more than three decades (Sharp and Hahn 2011). A recent report from UNAIDS indicated that an estimated 35 million people were living with HIV-1 worldwide and 2.1 million became newly infected (UNAIDS, 2014). Antiretroviral therapy (ART) is a current treatment for HIV-1 infection (Hammer et al, 2008). ART can suppress HIV-1 replication and reduce the morbidity and mortality rate in H... περισσότερα »
Challenges in HIV persistent viral replication regardless of potent antiretroviral therapy
Challenges in HIV persistent viral replication regardless of potent antiretroviral therapy: Abstract Though nowadays combined antiretroviral treatment (cART) is effective at suppressing viral replication to below the detection limits of plasma HIV-1 RNA assays, it is not yet considered a curative therapy, because HIV-1 continues to replicate in the so called viral reservoirs (Riddler et al, 2016; Sahu 2015; Barouch and Deeks 2014). Treated HIV-patients need to continue life-long therapy; otherwise, after stopping therapy, most patients will experience a rebound in plasma virus (Kea... περισσότερα »
Immunoexpression of tumor necrosis factor-alpha, interleukin-1alpha and interleukin-10 on odontogenic cysts and tumours
Immunoexpression of tumor necrosis factor-alpha, interleukin-1alpha and interleukin-10 on odontogenic cysts and tumours: Abstract Aim To analyze the immunoreactivity of IL-1α, TNF-α and IL-10 in odontogenic cysts and tumours and to investigate possible associations with established biological behaviors of these different lesions. Methodology Immunohistochemical expression of anti-IL-1α, anti-TNF-α and anti-IL-10 antibodies was assessed on epithelium and mesenchyme of 20 radicular cysts (RCs), 20 residual cysts (RECs), 20 dentigerous cysts (DCs), 18 solid ameloblastomas (SAs) and 20 ... περισσότερα »
Velopharyngeal changes after maxillary distraction in cleft patients
using a rigid external distraction device:A retrospective study: The Angle Orthodontist, Ahead of Print. *Mahasen Tahaa; Yasser M. Elsheikhb* a Associate Professor, Orthodontic Department, Faculty of Dentistry, Mansoura University, Mansoura, Egypt b Assistant Professor of Plastic Surgery, Faculty of Medicine, Menuofyia University, Menuofyia, Egypt Corresponding author: Dr Mahasen Taha, Mansoura University, Faculty of Dentistry, Mansoura 35516, Egypt (email:anbortho@hotmail.com) ABSTRACT *Objective: * To evaluate early and late velopharyngeal changes in cleft lip and palate (CLP)... περισσότερα »
Silver(I) carbohydrate complexes 3 and 4 might function as novel antimicrobial agents for the treatment of periodontal, carious or endodontic diseases.
Antibacterial effect of silver (I) carbohydrate complexes on oral pathogenic key species in vitro: Abstract BackgroundIt was the aim of this study to evaluate the antibacterial impact of two silver(I) carbohydrate complexes with tripodal thioglycosides, namely tris[2-(β-D-thio-glucopyranosyl)ethyl]-amine-silver(I)-nitrate (*3*) and tris[2-(α-D-thio-manno-pyranosyl)ethyl]-amine-silver(I)-nitrate (*4*), on five oral pathogenic bacterial strains. Furthermore, cytocompatibility was tested using human gingival fibroblasts (HGF). MethodsMinimum inhibitory concentrations (MIC) were de... περισσότερα »
Top-Down Processes in Simulated Electric-Acoustic Hearing: The Effect of Linguistic Context on Bimodal Benefit for Temporally Interrupted Speech.
Top-Down Processes in Simulated Electric-Acoustic Hearing: The Effect of Linguistic Context on Bimodal Benefit for Temporally Interrupted Speech.: Objectives: Previous studies have documented the benefits of bimodal hearing as compared with a cochlear implant alone, but most have focused on the importance of bottom-up, low-frequency cues. The purpose of the present study was to evaluate the role of top-down processing in bimodal hearing by measuring the effect of sentence context on bimodal benefit for temporally interrupted sentences. It was hypothesized that low-frequency acoustic ...περισσότερα »
Implantation of the Auditory Nerve via the Middle Ear Cavity in Rats with Partial Hearing Preservation
Implantation of the Auditory Nerve via the Middle Ear Cavity in Rats with Partial Hearing Preservation: The aim of this study was to evaluate the residual hearing function and cochlear morphology after auditory nerve implantation via middle ear spaces in rats. A titanium rod (1.5 mm long and 0.3 mm thick) coated with Parylene was inserted in the cochlear apex in the direction of the modiolus in 9 Wistar rats. Auditory brainstem-evoked responses to tone bursts at 2, 8, 12 and 32 kHz were recorded before surgery and on postoperative days 0, 2, 15 and 30. Eight cochleas were examined m... περισσότερα »
Data Mining FAERS to Analyze Molecular Targets of Drugs Highly Associated with Stevens-Johnson Syndrome.
Data Mining FAERS to Analyze Molecular Targets of Drugs Highly Associated with Stevens-Johnson Syndrome.: [image: http:--production.springer.de-OnlineReso] Authors: Burkhart KK, Abernethy D, Jackson D Abstract Drug features that are associated with Stevens-Johnson syndrome (SJS) have not been fully characterized. A molecular target analysis of the drugs associated with SJS in the FDA Adverse Event Reporting System (FAERS) may contribute to mechanistic insights into SJS pathophysiology. The publicly available version of FAERS was analyzed to identify disproportionality among the m... περισσότερα »
An overlap syndrome, with an unclear diagnosis between sarcoidosis, drug reaction or rash with eosinophilia and systemic symptoms and/or hypereosinophilic syndrome and Still's disease
Is this still just sarcoidosis, or should we a-DRESS a different diagnosis?: [image: http:--highwire.stanford.edu-icons-exter] Authors: Rolls S, Hyams C, Sheaff M, O'Shaughnessy TC Abstract An Afro-Caribbean woman presented with worsening breathlessness, weight loss, lethargy and fevers, developing a bilateral florid erythematous rash on her legs. She was recently diagnosed with rheumatoid arthritis and bilateral hilar lymphadenopathy was found on thoracic CT imaging. She was tachycardic and investigations revealed pancytopenia, eosinophilia, raised serum ACE, acute kidney injury... περισσότερα »
Worsening breathlessness, weight loss, lethargy and fevers, developing a bilateral florid erythematous rash
*Is this still just sarcoidosis, or should we a-DRESS a different diagnosis?: * [image: http:--highwire.stanford.edu-icons-exter] Authors: Rolls S, Hyams C, Sheaff M, O'Shaughnessy TC Abstract An Afro-Caribbean woman presented with worsening breathlessness, weight loss, lethargy and fevers, developing a bilateral florid erythematous rash on her legs. She was recently diagnosed with rheumatoid arthritis and bilateral hilar lymphadenopathy was found on thoracic CT imaging. She was tachycardic and investigations revealed pancytopenia, eosinophilia, raised serum ACE, acute kidney inju... περισσότερα »
Neurologic appearence of Behçet disease treated with adalimumab with good result
[Neurologic appearence of Behçet disease in 14-year old boy treated with adalimumab with good result].: *[Neurologic appearence of Behçet disease in 14-year old boy treated with adalimumab with good result].* Pol Merkur Lekarski. 2016 Feb;40(236):110-2 Authors: Iwańczak B, Reich A, Kofla-Dłubacz A, Kazanowska B, Ruczka M Abstract Behçet disease is a multiorgan inflammatory vessel disorder of unknown etiology which only occasionally occurs in children. Here, we demonstrate a 14-year-old boy with Behçet disease diagnosed based on recurrent aphthous stomatitis, acneiform facial lesi... περισσότερα »
Neurologic appearence of Behçet disease in children
[Neurologic appearence of Behçet disease in 14-year old boy treated with adalimumab with good result].: Pol Merkur Lekarski. 2016 ;40(236):110-2 Authors: Iwańczak B, Reich A, Kofla-Dłubacz A, Kazanowska B, Ruczka M Abstract Behçet disease is a multiorgan inflammatory vessel disorder of unknown etiology which only occasionally occurs in children. Here, we demonstrate a 14-year-old boy with Behçet disease diagnosed based on recurrent aphthous stomatitis, acneiform facial lesions, subpreputial erosions and extensive thrombosis involving sigmoid sinus, transverse sinus and right intern...περισσότερα »
Effect of polaprezinc on oral mucositis, irradiation period, and time to discharge in patients with head and neck cancer.
Effect of polaprezinc on oral mucositis, irradiation period, and time to discharge in patients with head and neck cancer.: Head Neck. 2016 Mar 22; Authors: Suzuki A, Kobayashi R, Shakui T, Kubota Y, Fukita M, Kuze B, Aoki M, Sugiyama T, Mizuta K, Itoh Y Abstract BACKGROUND: The purpose of the present study was to determine whether polaprezinc suspension in sodium alginate (P-AG) reduces the irradiation period and time to discharge after completion of radiotherapy in patients with head and neck cancer. METHODS: The incidence and severity of oral mucositis, the irradiation period, ...περισσότερα »
Sucralfate Mouth Wash in Prevention of 5-fluorouracil Induced Oral Mucositis
: A Prospective, Randomized, Double-Blind, Controlled Trial.: Nutr Cancer. 2016 Mar 23;:1-8 Authors: Ala S, Saeedi M, Janbabai G, Ganji R, Azhdari E, Shiva A Abstract Sucralfate has been used for the prevention and treatment of radiotherapy- and chemotherapy-induced stomatitis and mucositis in a number of studies, but the results are contradictory. To answer such discrepancies, the present study was designed to evaluate the efficacy of sucralfate mouthwash in prevention of 5-fluorouracil (5-FU)-induced oral mucositis in patients with gastrointestinal malignancies. Patients with gas... περισσότερα »
Volumes of Velopharyngeal and Glossopharyngeal Airway Were Not Changed after Uvulopalatopharyngoplasty
Report of Three Cases: Objective. The aim of this study was to investigate the changes in velopharyngeal and glossopharyngeal airway morphology and volume after uvulopalatopharyngoplasty in three adult obstructive sleep apnea syndrome patients who had bilateral large tonsils using three-dimensional computed tomography. Case Report. All three patients (one male and two females) who presented with a history of heavy snoring and excessive daytime sleepiness were examined with overnight nocturnal polysomnography, which indicated moderate-to-severe obstructive sleep apnea syndrome. Becau... περισσότερα »
Vibrent Smartphone Mobile Application
Vibrent Smartphone Mobile Application: *Condition*: Mucositis *Intervention*: Other: Vibrogent Smartphone Application *Sponsor*: Sidney Kimmel Comprehensive Cancer Center This research is being done to evaluate whether or not a customized version of the VibrentTM (formerly FitNinjaTM) mobile app is a feasible way to help people manage and control the pain from radiation sores (also referred to as "mucositis") when treating head and neck cancers with radiation. The mobile app will be designed to help people better understand the pain from the radiation sores and how to better...περισσότερα »
Pembrolizumab Plus Docetaxel for the Treatment of Recurrent or Metastatic Head and Neck Cancer
Pembrolizumab Plus Docetaxel for the Treatment of Recurrent or Metastatic Head and Neck Cancer: *Condition*: Head and Neck Carcinoma *Interventions*: Drug: Docetaxel; Drug: Pembrolizumab *Sponsor*: Medical University of Vienna Squamous cell carcinoma of the head and neck, which accounts for 90% of head and neck cancers, is the tenth most common cancer worldwide with over 650000 new cases per year. The major risk factors for HNSCC development comprise alcohol and tobacco consumption. During the last decades human papilloma virus infection (HPV) has been identified to contri...περισσότερα »
Nanomaterial–protein interactions: the case of pristine and functionalized carbon nanotubes and porcine gastric mucin
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 27 δευτερόλεπτα
Abstract Mucus represents a serious obstacle that prevents the penetration of drug carrier’s transport across the mucus barrier. This study highlights the interaction between mucin glycoprotein, mucin from porcine stomach Type III (PGM) and different pristine and functionalized single-wall and multi-wall carbon nanotubes (CNTs), under physiological conditions, in order to investigate the affinity of different […]
Cytotoxicity of semiconductor nanoparticles in A549 cells is attributable to their intrinsic oxidant activity
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 27 δευτερόλεπτα
Abstract Copper indium gallium diselenide (CIGS) and cadmium sulfide (CdS) nanoparticles (NP) are next generation semiconductors used in photovoltaic cells (PV). They possess high quantum efficiency, absorption coefficient, and cheaper manufacturing costs compared to silicon. Due to their potential for an industrial development and the lack of information about the risk associated in their use, […]
Validation of an air–liquid interface toxicological set-up using Cu, Pd, and Ag well-characterized nanost ructured aggregates and spheres
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 27 δευτερόλεπτα
Abstract Systems for studying the toxicity of metal aggregates on the airways are normally not suited for evaluating the effects of individual particle characteristics. This study validates a set-up for toxicological studies of metal aggregates using an air–liquid interface approach. The set-up used a spark discharge generator capable of generating aerosol metal aggregate particles and […]
Vestibular evoked myogenic potentials (VEMPs): Tailoring methodology to specific conditions.
*Vestibular evoked myogenic potentials (VEMPs): Tailoring methodology to specific conditions.* Clin Neurophysiol. 2016 Mar 11; Authors: Papathanasiou ES PMID: 27005456 [PubMed - as supplied by publisher] from Head and Neck on PubMed via xlomafota13 on Inoreader http://ift.tt/1Pt82HE via IFTTT
Completely resected follicular dendritic cell sarcoma of the posterior mediastinum: report of a case.
*Completely resected follicular dendritic cell sarcoma of the posterior mediastinum: report of a case.* Surg Case Rep. 2016 Dec;2(1):28 Authors: Miyoshi R, Sonobe M, Miyamoto E, Date H Abstract Follicular dendritic cell sarcoma is a rare malignant neoplasm originating from follicular dendritic cells, and most of them develop in lymph nodes of the head and neck. One third of follicular dendritic cell sarcomas occur in the extranodal sites such as the tonsils, mesentery, and retroperitoneal organs, but those of mediastinal origin are rare. Here, we present the case of a 16-year-old... περισσότερα »
Endocranial Morphology of the Primitive Nodosaurid Dinosaur Pawpawsaurus campbelli from the Early Cretaceous of North America.
*Endocranial Morphology of the Primitive Nodosaurid Dinosaur Pawpawsaurus campbelli from the Early Cretaceous of North America.* PLoS One. 2016;11(3):e0150845 Authors: Paulina-Carabajal A, Lee YN, Jacobs LL Abstract BACKGROUND: Ankylosaurs are one of the least explored clades of dinosaurs regarding endocranial anatomy, with few available descriptions of braincase anatomy and even less information on brain and inner ear morphologies. The main goal of this study is to provide a detailed description of the braincase and internal structures of the Early Cretaceous nodosaurid Pawpawsa... περισσότερα »
Corrigendum.
*Corrigendum.* Cancer Biol Ther. 2016 Mar 3;17(3):336 Authors: PMID: 27007262 [PubMed - as supplied by publisher] from Head and Neck on PubMed via xlomafota13 on Inoreader http://ift.tt/1ZvROVQ via IFTTT
A Triad of Telomerase, Androgen Receptor and Early Growth Response 1 in Prostate Cancer Cells.
*A Triad of Telomerase, Androgen Receptor and Early Growth Response 1 in Prostate Cancer Cells.* Cancer Biol Ther. 2016 Mar 22;:0 Authors: Jacob S, Nayak S, Kakar R, Chaudhari UK, Joshi D, Vundinti BR, Fernandes G, Barai RS, Kholkute SD, Sachdeva G Abstract Telomerase activation is one of the key mechanisms that allow cells to bypass replicative senescence. Telomerase activity is primarily regulated at the level of transcription of its catalytic unit- hTERT. Prostate cancer (PCa), akin to other cancers, is characterized by high telomerase activity. Existing data suggest that hTER... περισσότερα »
Triptolide mitigates radiation-induced pulmonary fibrosis via inhibition of axis of alveolar macrophages-NOXes-ROS-myofibroblasts.
*Triptolide mitigates radiation-induced pulmonary fibrosis via inhibition of axis of alveolar macrophages-NOXes-ROS-myofibroblasts.* Cancer Biol Ther. 2016 Mar 22;:1-9 Authors: Chen C, Yang S, Zhang M, Zhang Z, Hong J, Han D, Ma J, Zhang SB, Okunieff P, Zhang L Abstract PURPOSE: IR-induced pulmonary fibrosis is one of the most severe late complications of radiotherapy for lung cancer. It is urgently needed to discover a new drug for anti-IR lung fibrosis. Our previous studies have indicated that TPL exhibits both anti-IR lung fibrosis and anti-tumor activities. To reveal the mech...περισσότερα »
Fibrodysplasia ossificans progressiva: initial presentation with a preosseous lesion of the scalp and its MRI appearance.
*Fibrodysplasia ossificans progressiva: initial presentation with a preosseous lesion of the scalp and its MRI appearance.* Skeletal Radiol. 2016 Mar 22; Authors: Lin FY, Lin CH, Shu G, Chen CK Abstract This case subject is a 1-year-old girl presenting with recurrent diffuse soft-tissue swelling of the scalp and periorbital region. Her family denied any known history of trauma. There was no obvious discoloration or local heat at the lesion. Magnetic resonance imaging (MRI) revealed diffuse soft tissue swelling of the scalp manifesting as high signal intensity on T2-weighted image... περισσότερα »
Reconsidering the benefit of intermittent versus continuous treatment in the maintenance treatment setting of metastatic colorectal cancer.
*Reconsidering the benefit of intermittent versus continuous treatment in the maintenance treatment setting of metastatic colorectal cancer.* Cancer Treat Rev. 2016 Mar 14;45:97-104 Authors: Sunakawa Y, Bekaii-Saab T, Stintzing S Abstract Colorectal cancer is one of the most frequent solid tumors in the western world, with low survival rates in patients with metastatic disease. Doublet chemotherapy regimens such as FOLFOX or FOLFIRI are the mainstay of standard first-line chemotherapy in the metastatic setting. The conventional treatment as a first-line approach is continuous appl...περισσότερα »
macrophage; +89 new citations
89 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: *macrophage* These pubmed results were generated on 2016/03/24 PubMed comprises more than 24 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites. from Head and Neck on PubMed via xlomafota13 on Inoreader http://ift.tt/1pzUTHE via IFTTT
Assessing perioperative complications associated with use of intraoperative magnetic resonance imaging during glioma surgery - a single centre experience with 516 cases.
*Assessing perioperative complications associated with use of intraoperative magnetic resonance imaging during glioma surgery - a single centre experience with 516 cases.* Br J Neurosurg. 2016 Mar 23;:1-4 Authors: Ahmadi R, Campos B, Haux D, Rieke J, Beigel B, Unterberg A Abstract BACKGROUND: Intraoperative magnetic resonance imaging (io-MRI) improves the extent of glioma resection. Due to the magnetic field, patients have to be covered with sterile drape and are then transferred into an io-MRI chamber, where ferromagnetic anaesthesia monitors and machines must be kept at distanc... περισσότερα »
Extensive basal ganglia hematomas treated by local thrombolysis versus conservative management - a comparative retrospective analysis.
*Extensive basal ganglia hematomas treated by local thrombolysis versus conservative management - a comparative retrospective analysis.* Br J Neurosurg. 2016 Mar 23;:1-6 Authors: Xu F, Lian L, Liang Q, Zhu W, Liu X, Kang H, Zhang M, Wang F, Xue Z, Tang Z, Zhu S Abstract OBJECTIVES: Single-target puncture plus catheter insertion into the clot is a routine step in hematoma aspiration and local thrombolysis for spontaneous intracerebral haemorrhage (ICH). However, multiple-target puncture of this procedure may imply faster hematoma reduction for large-area ICH. We retrospectively ex...περισσότερα »
Retrospective analysis of anterior skull base CSF leaks and endoscopic repairs at Leeds.
*Retrospective analysis of anterior skull base CSF leaks and endoscopic repairs at Leeds.* Br J Neurosurg. 2016 Mar 23;:1-5 Authors: Nix P, Tyagi A, Phillips N Abstract OBJECTIVES: Over the past 10 years, endoscopic endonasal anterior skull base surgery has become established practice. Surgeons carrying out this surgery need to be able to endoscopically repair primary and secondary CSF leaks. A growing number of techniques have been adopted to date. This article highlights one UK institution's experience in the management of anterior skull base leaks, and how surgeons there have ... περισσότερα »
Ruptured blebs and racing hearts: autonomic cardiac changes in neurosurgeons during microsurgical clipping of aneurysms.
*Ruptured blebs and racing hearts: autonomic cardiac changes in neurosurgeons during microsurgical clipping of aneurysms.* Br J Neurosurg. 2016 Mar 23;:1-3 Authors: Ganne C, Talkad SN, Srinivas D, Somanna S Abstract INTRODUCTION: In this study, we intend to evaluate the autonomic changes occurring in neurosurgeons and thus the stress during microsurgical clipping of aneurysms. AIMS AND OBJECTIVES: The aim of the current study is to evaluate the heart rate variability (HRV) of the neurosurgeons during microsurgical clipping of aneurysm by using continuous real time monitoring of th... περισσότερα »
A comparison of the Full Outline of UnResponsiveness (FOUR) score and Glasgow Coma Score (GCS) in predictive modelling in traumatic brain injury.
*A comparison of the Full Outline of UnResponsiveness (FOUR) score and Glasgow Coma Score (GCS) in predictive modelling in traumatic brain injury.* Br J Neurosurg. 2016 Mar 22;:1-10 Authors: Kasprowic K, Burzynska M, Melcer T, Kübler A Abstract OBJECTIVES: To compare the performance of multivariate predictive models incorporating either the Full Outline of UnResponsiveness (FOUR) score or Glasgow Coma Score (GCS) in order to test whether substituting GCS with the FOUR score in predictive models for outcome in patients after TBI is beneficial. MATERIAL AND METHODS: A total of 162 T... περισσότερα »
Improving neurosurgical communication and reducing risk and registrar burden using a novel online database referral platform.
*Improving neurosurgical communication and reducing risk and registrar burden using a novel online database referral platform.* Br J Neurosurg. 2016 Mar 22;:1-4 Authors: Matloob SA, Hyam JA, Thorne L, Bradford R Abstract OBJECTIVES: Documentation of urgent referrals to neurosurgical units and communication with referring hospitals is critical for effective handover and appropriate continuity of care within a tertiary service. Referrals to our neurosurgical unit were audited and we found that the majority of referrals were not documented and this led to more calls to the on-call n... περισσότερα »
The evaluation of eustachian tube paratubal structures using magnetic resonance imaging in patients with chronic suppurative otitis media.
*The evaluation of eustachian tube paratubal structures using magnetic resonance imaging in patients with chronic suppurative otitis media.* Acta Otolaryngol. 2016 Mar 23;:1-4 Authors: Terzi S, Beyazal Çeliker F, Özgür A, Çeliker M, Beyazal M, Demirci M, Dursun E Abstract Conclusion Eustachian tube (ET) dysfunction, which plays a role in the pathogenesis chronic suppurative otitis media (CSOM), does not seem to be due to differences in paratubal structures. Objective The aim of this study was to compare the magnetic resonance imaging (MRI) findings of the paratubal structures of ... περισσότερα »
Influence of cochlear implantation on vestibular function.
*Influence of cochlear implantation on vestibular function.* Acta Otolaryngol. 2016 Mar 23;:1-5 Authors: Chen X, Chen X, Zhang F, Qin Z Abstract Conclusion Vestibular function in patients can be damaged following cochlear implantation. Therefore, assessing the pre-operative vestibular status, carefully choosing the side of implantation, and preserving function by using minimally invasive surgical techniques are important. Objectives The aim of this study was to assess the influence of cochlear implantation on vestibular function in patients with severe and profound sensorineural ... περισσότερα »
speech and language; +16 new citations
16 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: *speech and language* These pubmed results were generated on 2016/03/24 PubMed comprises more than 24 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites. from Speech via xlomafota13 on Inoreader http://ift.tt/1UJiD9k
What Do Children with Chronic Diseases and Their Parents Think About Pediatricians? A Qualitative Interview Study.
*What Do Children with Chronic Diseases and Their Parents Think About Pediatricians? A Qualitative Interview Study.* Matern Child Health J. 2016 Mar 23; Authors: Konstantynowicz J, Marcinowicz L, Abramowicz P, Abramowicz M Abstract Objectives The aim of this study was to determine how pediatric patients and their parents perceive health care during hospital stays, what are their expectations of doctor behaviors, and which components of care do they consider to be the most important. Methods A qualitative descriptive study was carried out using the open interview technique. Twenty-...περισσότερα »
Patients need a strong voice in how NHS is run.
*Patients need a strong voice in how NHS is run.* Nurs Stand. 2016 Mar 23;30(30):3 Authors: Abstract Politicians, professionals and the public would surely all agree that patients must have a say in the way they access and receive NHS care, and the opportunity to provide feedback easily on their experience. However, the reality is that patients and other service users often struggle to be heard, not least if they seek redress when the quality of care does not meet their expectations. PMID: 27008108 [PubMed - as supplied by publisher] from Speech via xlomafota13 on Inoreader htt...περισσότερα »
Voice outcomes of laryngopharyngeal reflux treatment: a systematic review of 1483 patients.
*Voice outcomes of laryngopharyngeal reflux treatment: a systematic review of 1483 patients.* Eur Arch Otorhinolaryngol. 2016 Mar 23; Authors: Lechien JR, Finck C, Costa de Araujo P, Huet K, Delvaux V, Piccaluga M, Harmegnies B, Saussez S Abstract The aim of this study is to explore voice quality modifications in laryngopharyngeal reflux (LPR) disease and to understand better the pathophysiological mechanisms underlying the development of communicative disability. Biological Abstracts, BioMed Central, Cochrane database, PubMed and Scopus were assessed for subject headings using t...περισσότερα »
Scanning Electron Microscopy of the Presbylarynx.
*Scanning Electron Microscopy of the Presbylarynx.* Otolaryngol Head Neck Surg. 2016 Mar 22; Authors: Gonçalves TM, Dos Santos DC, Pessin AB, Martins RH Abstract OBJECTIVE: To describe the findings on the presbylarynx under scanning electron microscopy. STUDY DESIGN: Cadaver study. SETTING: Universidade Estadual Paulista (Botucatu, São Paulo, Brazil). SUBJECTS AND METHODS: Sixteen vocal folds were removed during necropsies and distributed into 2 age groups: control (n = 8; aged 30-50 years) and elderly (n = 8; aged 75-92 years). The right vocal fold was dissected, fixed in glutaral...περισσότερα »
Trends in cell phone use among children in the Danish national birth cohort at ages 7 and 11 years.
*Trends in cell phone use among children in the Danish national birth cohort at ages 7 and 11 years.* J Expo Sci Environ Epidemiol. 2016 Mar 23; Authors: Sudan M, Olsen J, Sigsgaard T, Kheifets L Abstract We prospectively examined trends in cell phone use among children in the Danish National Birth Cohort. Cell phone use was assessed at ages 7 and 11 years, and we examined use patterns by age, by year of birth, and in relation to specific individual characteristics. There was an increase in cell phone use from age 7 (37%) to 11 years (94%). There was a clear pattern of greater re... περισσότερα »
The Instrument of Voice: The "True" Vocal Cord or Vocal Fold?
*The Instrument of Voice: The "True" Vocal Cord or Vocal Fold?* J Voice. 2016 Mar 18; Authors: Hall A, Cobb R, Kapoor K, Kuchai R, Sandhu G PMID: 27005440 [PubMed - as supplied by publisher] from Speech via xlomafota13 on Inoreader http://ift.tt/1WKOBQs via IFTTT
Botulinum Toxin Dosing Trends in Spasmodic Dysphonia Over a 20-year Period.
*Botulinum Toxin Dosing Trends in Spasmodic Dysphonia Over a 20-year Period.* J Voice. 2016 Mar 18; Authors: Namin AW, Christopher KM, Eisenbeis JF Abstract OBJECTIVES: The study aims to (1) identify the botulinum toxin (BTX) dosing trend in a cohort of patients who received at least 20 injections for the treatment of adductor spasmodic dysphonia (ADSD), (2) describe two distinct BTX dosing trends in treating ADSD (a "classic" dosing trend that initially decreases before stabilizing, and a "fluctuating" dosing trend), and (3) determine if patients with the "classic" dosing trend ... περισσότερα »
Superiority of resection over enucleation for schwannomas of the cervical vagus nerve.
*Superiority of resection over enucleation for schwannomas of the cervical vagus nerve.* Int J Surg. 2016 Mar 19; Authors: Illuminati G, Pizzardi G, Minni A, Masci F, Ciamberlano B, Pasqua R, Calio FG, Vietri F Abstract INTRODUCTION: Schwannoma of the cervical vagus nerve is rare. Treatment options include intracapsular enucleation and en bloc resection. The purpose of this study was to compare the outcomes of enucleation and resection in terms of postoperative mortality and morbidity, freedom from vocal cord palsy, freedom from local recurrence, quality-adjusted life-year (QALY... περισσότερα »
Cross-Cultural Adaptation and Validation of the Voice Handicap Index into Thai.
*Cross-Cultural Adaptation and Validation of the Voice Handicap Index into Thai.* J Med Assoc Thai. 2015 Dec;98(12):1199-208 Authors: Jaruchinda P, Suwanwarangkool T Abstract BACKGROUND: The voice handicap index (VHI) is one of the most utilized instruments for measuring a patient's self-assessment of voice severity. The VHI has been translated into several languages, but not in Thai. OBJECTIVE: To examine the psychometric properties of a Thai translation of the voice Handicap Index (VHI) and assess the applicability in the screening diagnosis. MATERIAL AND METHOD: After receiving...περισσότερα »
Attentional Demand of a Virtual Reality-Based Reaching Task in Nondisabled Older Adults.
*Attentional Demand of a Virtual Reality-Based Reaching Task in Nondisabled Older Adults.* J Mot Learn Dev. 2015 Dec;3(2):91-109 Authors: Chen YA, Chung YC, Proffitt R, Wade E, Winstein C Abstract Attention during exercise is known to affect performance; however, the attentional demand inherent to virtual reality (VR)-based exercise is not well understood. We used a dual-task paradigm to compare the attentional demands of VR-based and non-VR-based (conventional, real-world) exercise: 22 non-disabled older adults performed a primary reaching task to virtual and real targets in a c...περισσότερα »
A lover or a fighter? Opposing sexual selection pressures on men's vocal pitch and facial hair.
*A lover or a fighter? Opposing sexual selection pressures on men's vocal pitch and facial hair.* Behav Ecol. 2016 Mar-Apr;27(2):512-519 Authors: Saxton TK, Mackey LL, McCarty K, Neave N Abstract The traditional assumption within the research literature on human sexually dimorphic traits has been that many sex differences have arisen from intersexual selection. More recently, however, there has been a shift toward the idea that many male features, including male lower-pitched voices and male beard growth, might have arisen predominantly through intrasexual selection: that is, to ...περισσότερα »
Retrospective analysis of anterior skull base CSF leaks and endoscopic repairs at Leeds.
*Retrospective analysis of anterior skull base CSF leaks and endoscopic repairs at Leeds.* Br J Neurosurg. 2016 Mar 23;:1-5 Authors: Nix P, Tyagi A, Phillips N Abstract OBJECTIVES: Over the past 10 years, endoscopic endonasal anterior skull base surgery has become established practice. Surgeons carrying out this surgery need to be able to endoscopically repair primary and secondary CSF leaks. A growing number of techniques have been adopted to date. This article highlights one UK institution's experience in the management of anterior skull base leaks, and how surgeons there have ... περισσότερα »
Ruptured blebs and racing hearts: autonomic cardiac changes in neurosurgeons during microsurgical clipping of aneurysms.
*Ruptured blebs and racing hearts: autonomic cardiac changes in neurosurgeons during microsurgical clipping of aneurysms.* Br J Neurosurg. 2016 Mar 23;:1-3 Authors: Ganne C, Talkad SN, Srinivas D, Somanna S Abstract INTRODUCTION: In this study, we intend to evaluate the autonomic changes occurring in neurosurgeons and thus the stress during microsurgical clipping of aneurysms. AIMS AND OBJECTIVES: The aim of the current study is to evaluate the heart rate variability (HRV) of the neurosurgeons during microsurgical clipping of aneurysm by using continuous real time monitoring of th... περισσότερα »
A comparison of the Full Outline of UnResponsiveness (FOUR) score and Glasgow Coma Score (GCS) in predictive modelling in traumatic brain injury.
*A comparison of the Full Outline of UnResponsiveness (FOUR) score and Glasgow Coma Score (GCS) in predictive modelling in traumatic brain injury.* Br J Neurosurg. 2016 Mar 22;:1-10 Authors: Kasprowic K, Burzynska M, Melcer T, Kübler A Abstract OBJECTIVES: To compare the performance of multivariate predictive models incorporating either the Full Outline of UnResponsiveness (FOUR) score or Glasgow Coma Score (GCS) in order to test whether substituting GCS with the FOUR score in predictive models for outcome in patients after TBI is beneficial. MATERIAL AND METHODS: A total of 162 T... περισσότερα »
Improving neurosurgical communication and reducing risk and registrar burden using a novel online database referral platform.
*Improving neurosurgical communication and reducing risk and registrar burden using a novel online database referral platform.* Br J Neurosurg. 2016 Mar 22;:1-4 Authors: Matloob SA, Hyam JA, Thorne L, Bradford R Abstract OBJECTIVES: Documentation of urgent referrals to neurosurgical units and communication with referring hospitals is critical for effective handover and appropriate continuity of care within a tertiary service. Referrals to our neurosurgical unit were audited and we found that the majority of referrals were not documented and this led to more calls to the on-call n... περισσότερα »
The evaluation of eustachian tube paratubal structures using magnetic resonance imaging in patients with chronic suppurative otitis media.
*The evaluation of eustachian tube paratubal structures using magnetic resonance imaging in patients with chronic suppurative otitis media.* Acta Otolaryngol. 2016 Mar 23;:1-4 Authors: Terzi S, Beyazal Çeliker F, Özgür A, Çeliker M, Beyazal M, Demirci M, Dursun E Abstract Conclusion Eustachian tube (ET) dysfunction, which plays a role in the pathogenesis chronic suppurative otitis media (CSOM), does not seem to be due to differences in paratubal structures. Objective The aim of this study was to compare the magnetic resonance imaging (MRI) findings of the paratubal structures of ... περισσότερα »
Influence of cochlear implantation on vestibular function.
*Influence of cochlear implantation on vestibular function.* Acta Otolaryngol. 2016 Mar 23;:1-5 Authors: Chen X, Chen X, Zhang F, Qin Z Abstract Conclusion Vestibular function in patients can be damaged following cochlear implantation. Therefore, assessing the pre-operative vestibular status, carefully choosing the side of implantation, and preserving function by using minimally invasive surgical techniques are important. Objectives The aim of this study was to assess the influence of cochlear implantation on vestibular function in patients with severe and profound sensorineural ... περισσότερα »
Clinicopathological analysis of salivary gland tissue from patients with IgG4-related disease.
*Clinicopathological analysis of salivary gland tissue from patients with IgG4-related disease.* Acta Otolaryngol. 2016 Mar 23;:1-5 Authors: Takano K, Nomura K, Abe A, Kamekura R, Yamamoto M, Ichimiya S, Takahashi H, Himi T Abstract Conclusion The diagnosis of immunoglobulin G4-related disease (IgG4-RD) should be based on the morphology of tissue biopsy, and this study recommends a submandibular gland (SMG) biopsy for accurate diagnosis and to exclude malignant disease. Objective To clarify which type of biopsy specimen (SMG or labial salivary gland [LSG]) should be taken from pa...περισσότερα »
T-status and an oral fluoropyrimidine, S-1, adjuvant chemotherapy are prognostic factors in reduced-RADPLAT for resectable hypopharyngeal cancer.
*T-status and an oral fluoropyrimidine, S-1, adjuvant chemotherapy are prognostic factors in reduced-RADPLAT for resectable hypopharyngeal cancer.* Acta Otolaryngol. 2016 Mar 23;:1-7 Authors: Wakisaka N, Hirai N, Kondo S, Aga M, Nakanishi Y, Tsuji A, Endo K, Murono S, Yoshizaki T Abstract CONCLUSION: Reduced-RADPLAT for HPC achieved comparative survival and locoregional control rates with lower toxicities compared with concurrent chemoradiotherapies including original RADPLAT. S-1 adjuvant chemotherapy showed a survival benefit. OBJECTIVES: To evaluate the efficacy and toxicities ... περισσότερα »
Constipation in Duchenne Muscular Dystrophy: Prevalence, Diagnosis, and Treatment
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 52 δευτερόλεπτα
Publication date: April 2016 Source:The Journal of Pediatrics, Volume 171 Author(s): Dror Kraus, Brenda L. Wong, Paul S. Horn, Ajay Kaul ObjectivesTo determine the prevalence and clinical characteristics of constipation among patients with Duchenne muscular dystrophy (DMD).Study designThis cross-sectional prospective study included 120 patients (age range 5-30 years old) with an established diagnosis of DMD. […]
Clinical approaches toward asthma and COPD based on the heterogeneity of disease pathogenesis
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 52 δευτερόλεπτα
Abstract Asthma and chronic obstructive pulmonary disease (COPD) are each heterogeneous disease classifications that include several clinical and pathophysiological phenotypes. This heterogeneity complicates characterization of each disease and, in some cases, hinders the selection of appropriate treatment. Therefore, in recent years, emphasis has been placed on improving our understanding of the various phenotypes of asthma […]
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fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 52 δευτερόλεπτα
Publication date: April 2016 Source:The Journal of Pediatrics, Volume 171 from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/22HvnPd via IFTTT
Immunohistochemical expression of GLUT-1, GLUT-3, and carbonic anhydrase IX in benign odontogenic lesions
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 52 δευτερόλεπτα
Background Some benign odontogenic lesions have a distinct biological behavior with high recurrence rates and local aggressive behavior. To determine whether glucose transporters proteins (GLUT-1 and GLUT-3) and carbonic anhydrase IX (CA IX) are associated with the development of as dentigerous cyst (DC), odontogenic keratocyst (OK), and ameloblastoma (AM), we evaluated the immunohistochemical expression of […]
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fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 52 δευτερόλεπτα
Publication date: April 2016 Source:The Journal of Pediatrics, Volume 171 from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1LJ5ESi via IFTTT
Can we adhere to guidelines better?
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 52 δευτερόλεπτα
Publication date: April 2016 Source:The Journal of Pediatrics, Volume 171 Author(s): Paul G. Fisher from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/22HvnyL via IFTTT
Viruses, upper respiratory tract illnesses, and sinusitis
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 52 δευτερόλεπτα
Publication date: April 2016 Source:The Journal of Pediatrics, Volume 171 Author(s): Sarah S. Long from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1LJ5Fpn via IFTTT
50 Years Ago in The Journal of Pediatrics
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 52 δευτερόλεπτα
Publication date: April 2016 Source:The Journal of Pediatrics, Volume 171 Author(s): Sharon P. Andreoli from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/22Hvnig via IFTTT
We are here because my child complained of being dizzy
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 52 δευτερόλεπτα
Publication date: April 2016 Source:The Journal of Pediatrics, Volume 171 Author(s): Reginald L. Washington from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1LJ5CtK via IFTTT
Table of Contents
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 52 δευτερόλεπτα
Publication date: April 2016 Source:The Journal of Pediatrics, Volume 171 from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/22Hvn1K via IFTTT
Materials modelling: The frontiers and the challenges.
*Materials modelling: The frontiers and the challenges.* Nat Mater. 2016 Mar 23;15(4):381-2 Authors: Marzari N PMID: 27005917 [PubMed - in process] from #PubMed 3 via ola Kala on Inoreader http://ift.tt/1XPBOMM via IFTTT
Exposure to famine in early life and non-alcoholic fatty liver disease in adulthood.
*Exposure to famine in early life and non-alcoholic fatty liver disease in adulthood.* J Clin Endocrinol Metab. 2016 Mar 22;:jc20161076 Authors: Wang N, Chen Y, Ning Z, Li Q, Han B, Zhu C, Chen Y, Xia F, Jiang B, Wang B, Wang X, Jensen MD, Lu Y Abstract CONTEXT: Epidemiologic studies have indicated that early-life nutrition influences later risk of obesity, type 2 diabetes and metabolic syndrome. Non-alcoholic fatty liver disease (NAFLD) is also considered a metabolic disease. OBJECTIVE: The aim was to explore the association between adult NAFLD and fetal or childhood exposure to...περισσότερα »
Metabolic and Transcriptional Changes in Cultured Muscle Stem Cells from Low Birth Weight Subjects.
*Metabolic and Transcriptional Changes in Cultured Muscle Stem Cells from Low Birth Weight Subjects.* J Clin Endocrinol Metab. 2016 Mar 22;:jc20154214 Authors: Hansen NS, Hjort L, Broholm C, Gillberg L, Schrölkamp M, Schultz HS, Mortensen B, Jørgensen SW, Friedrichsen M, Wojtaszewski JF, Pedersen BK, Vaag A Abstract CONTEXT/OBJECTIVE: Developmental programming of human muscle stem cells could in part explain why individuals born with low birth weight (LBW) have an increased risk of developing type 2 diabetes (T2D) later in life. We hypothesized that immature muscle stem cell func... περισσότερα »
Steroid sulfatase sulfatase deficiency and androgen activation before and after puberty.
*Steroid sulfatase sulfatase deficiency and androgen activation before and after puberty.* J Clin Endocrinol Metab. 2016 Mar 22;:jc20154101 Authors: Idkowiak J, Taylor AE, Subtil S, O'Neil DM, Vijzelaar R, Dias RP, Amin R, Barrett TG, Shackleton CH, Kirk JM, Moss C, Arlt W Abstract CONTEXT: Steroid sulfatase (STS) cleaves the sulfate moiety off steroid sulfates, including DHEAS, the inactive sulfate ester of the adrenal androgen precursor DHEA. Deficient DHEA sulfation, the opposite enzymatic reaction to that catalyzed by STS, results in androgen excess by increased conversion of... περισσότερα »
Acute female hypogonadism alters adipose tissue fatty acid storage factors and chylomicronemia.
*Acute female hypogonadism alters adipose tissue fatty acid storage factors and chylomicronemia.* J Clin Endocrinol Metab. 2016 Mar 22;:jc20154065 Authors: Santosa S, Bonnes SL, Jensen MD Abstract CONTEXT: Chronic sex steroid deficiency has effects on adipose fatty acid (FA) storage mechanisms and fat oxidation, but the chronology of events not well understood. OBJECTIVE: To examine the acute effects of female sex steroid suppression on cellular mechanisms affecting abdominal and femoral subcutaneous adipose tissue FA storage. DESIGN: Randomized, longitudinal, parallel study desig... περισσότερα »
Fibroblast Growth Factor-23 (FGF-23) Levels Differ Across Populations by Degree of Industrialization.
*Fibroblast Growth Factor-23 (FGF-23) Levels Differ Across Populations by Degree of Industrialization.* J Clin Endocrinol Metab. 2016 Mar 22;:jc20153558 Authors: Yuen SN, Kramer H, Luke A, Bovet P, Plange-Rhule J, Forrester T, Lambert V, Wolfe M, Camacho P, Harders R, Dugas L, Cooper R, Durazo-Arvizu R Abstract CONTEXT: Compensatory increases in FGF23 with increasing phosphate intake may adversely impact health. However, population and clinical studies examining the link between phosphate intake and FGF23 levels have focused mainly on populations living in highly industrialized so...περισσότερα »
Female Reproductive Disorders, Diseases, and Costs of Exposure to Endocrine Disrupting Chemicals in the European Union.
*Female Reproductive Disorders, Diseases, and Costs of Exposure to Endocrine Disrupting Chemicals in the European Union.* J Clin Endocrinol Metab. 2016 Mar 22;:jc20152873 Authors: Hunt PA, Sathyanarayana S, Fowler PA, Trasande L Abstract CONTEXT: A growing body of evidence suggests that endocrine-disrupting chemicals (EDCs) contribute to female reproductive disorders. OBJECTIVE: To calculate the associated combined health care and economic costs attributable to specific EDC exposures within the European Union (EU). DESIGN: An expert panel evaluated evidence for probability of causat... περισσότερα »
Longitudinal Changes in Resting-State Cerebral Activity in Patients with First-Episode Schizophrenia: A 1-Year Follow-up Functional MR Imaging Study.
*Longitudinal Changes in Resting-State Cerebral Activity in Patients with First-Episode Schizophrenia: A 1-Year Follow-up Functional MR Imaging Study.* Radiology. 2016 Jan 26;:151334 Authors: Li F, Lui S, Yao L, Hu J, Lv P, Huang X, Mechelli A, Sweeney JA, Gong Q Abstract Purpose To determine whether the brain functional abnormalities of drug-naive first-episode schizophrenia are reduced after 1 year of undergoing antipsychotic treatment and whether pretreatment resting-state functional magnetic resonance (MR) imaging parameters are associated with longitudinal changes in clinic...περισσότερα »
Quantitative Sodium MR Imaging at 7 T: Initial Results and Comparison with Diffusion-weighted Imaging in Patients with Breast Tumors.
*Quantitative Sodium MR Imaging at 7 T: Initial Results and Comparison with Diffusion-weighted Imaging in Patients with Breast Tumors.* Radiology. 2016 Jan 27;:151304 Authors: Zaric O, Pinker K, Zbyn S, Strasser B, Robinson S, Minarikova L, Gruber S, Farr A, Singer C, Helbich TH, Trattnig S, Bogner W Abstract Purpose To investigate the clinical feasibility of a quantitative sodium 23 ((23)Na) magnetic resonance (MR) imaging protocol developed for breast tumor assessment and to compare it with 7-T diffusion-weighted imaging (DWI). Materials and Methods Written informed consent in t... περισσότερα »
Correlates of Executive Functions in Multiple Sclerosis Based on Structural and Functional MR Imaging: Insights from a Multicenter Study.
*Correlates of Executive Functions in Multiple Sclerosis Based on Structural and Functional MR Imaging: Insights from a Multicenter Study.* Radiology. 2016 Mar 22;:151809 Authors: Koini M, Filippi M, Rocca MA, Yousry T, Ciccarelli O, Tedeschi G, Gallo A, Ropele S, Valsasina P, Riccitelli G, Damjanovic D, Muhlert N, Mancini L, Fazekas F, Enzinger C, MAGNIMS fMRI Study Group Abstract Purpose To study the concomitant use of structural and functional magnetic resonance (MR) imaging correlates to explain information processing speed (IPS) and executive function (EF) in multiple scleros... περισσότερα »
Preliminary data of the antipancreatic tumor efficacy and toxicity of long-circulating and pH-sensitive liposomes containing cisplatin.
*Preliminary data of the antipancreatic tumor efficacy and toxicity of long-circulating and pH-sensitive liposomes containing cisplatin.* Nucl Med Commun. 2016 Mar 22; Authors: Carlesso FN, Araújo RS, Fuscaldi LL, Mendes Miranda SE, Rubello D, Teixeira CS, Dos Reis DC, Leite EA, Silveira JN, Fernandes SO, Cassali GD, de Oliveira MC, Colletti PM, de Barros AL, Cardoso VN Abstract PURPOSE: Pancreatic cancer is the fourth most common cause of cancer-related death in the USA. This is mainly because of the chemoresistance of this type of tumor; thus, the development of novel therapeut...περισσότερα »
Free 25-hydroxyvitamin D: impact of vitamin D binding protein assays on racial-genotypic associations.
*Free 25-hydroxyvitamin D: impact of vitamin D binding protein assays on racial-genotypic associations.* J Clin Endocrinol Metab. 2016 Mar 23;:jc20161104 Authors: Nielson CM, Jones KS, Chun RF, Jacobs JM, Wang Y, Hewison M, Adams JS, Swanson CM, Lee CG, Vanderschueren D, Pauwels S, Prentice A, Smith RD, Shi T, Gao Y, Schepmoes AA, Zmuda JM, Lapidus J, Cauley JA, Bouillon R, Schoenmakers I, Orwoll ES Abstract CONTEXT: Total 25-hydroxyvitamin D (25OHD) is a marker of vitamin D status and is lower in African Americans than in whites. Whether this difference holds for free 25OHOD (f2... περισσότερα »
Affordable Care Act Implementation: Challenges and Opportunities to Impact Patients With Diabetes.
*Affordable Care Act Implementation: Challenges and Opportunities to Impact Patients With Diabetes.* J Clin Endocrinol Metab. 2016 Mar 23;:jc20161047 Authors: Powers AC, Wexler JA, Lash RW, Dyer MC, Becker MN, Vigersky RA PMID: 27007692 [PubMed - as supplied by publisher] from #PubMed 1 via ola Kala on Inoreader http://ift.tt/1Pt4NQt via IFTTT
Long-term Results of GH Treatment in Silver-Russell Syndrome (SRS): Do They Benefit the Same as Non-SRS Short-SGA?
*Long-term Results of GH Treatment in Silver-Russell Syndrome (SRS): Do They Benefit the Same as Non-SRS Short-SGA?* J Clin Endocrinol Metab. 2016 Mar 23;:jc20154273 Authors: Smeets CC, Zandwijken GR, Renes JS, Hokken-Koelega AC Abstract CONTEXT: Silver-Russell syndrome (SRS) is a genetically heterogeneous syndrome characterized by low birth weight, severe short stature and variable dysmorphic features. Growth hormone (GH) treatment is a registered growth-promoting therapy for short children born small for gestational age (SGA), including SRS, but there are limited data on the GH-... περισσότερα »
Cumulus Cell Mitochondrial Resistance To Stress In Vitro Predicts Oocyte Development During Assisted Reproduction.
*Cumulus Cell Mitochondrial Resistance To Stress In Vitro Predicts Oocyte Development During Assisted Reproduction.* J Clin Endocrinol Metab. 2016 Mar 22;:jc20161464 Authors: Dumesic DA, Guedikian AA, Madrigal VK, Phan JD, Hill DL, Alvarez JP, Chazenbalk GD Abstract CONTEXT: Complex cumulus cell-oocyte interactions govern energy utilization during oocyte development. OBJECTIVE: This study investigates the relationship of cumulus cell mitochondria with oocyte development during ovarian stimulation for in vitro fertilization (IVF). DESIGN: This is a prospective cohort study. SETTING...περισσότερα »
Deletion of CPEB1 gene: a rare but recurrent cause of premature ovarian insufficiency (POI).
*Deletion of CPEB1 gene: a rare but recurrent cause of premature ovarian insufficiency (POI).* J Clin Endocrinol Metab. 2016 Mar 22;:jc20161291 Authors: Hyon C, Mansour-Hendili L, Chantot-Bastaraud S, Donadille B, Kerlan V, Dodé C, Jonard S, Delemer B, Gompel A, Reznik Y, Touraine P, Siffroi J, Christin-Maitre S Abstract CONTEXT: Premature ovarian insufficiency (POI) may be secondary to chemotherapy, radiotherapy or environmental factors. Genetic causes are identified in 20-25% of cases, but most POI cases remain idiopathic. OBJECTIVE: To identify new genes involved in POI and to ...περισσότερα »
Cholecystokinin-Induced Gallbladder Emptying and Single-Dose Metformin Elicit Additive Glucagon-Like Peptide-1 Responses.
*Cholecystokinin-Induced Gallbladder Emptying and Single-Dose Metformin Elicit Additive Glucagon-Like Peptide-1 Responses.* J Clin Endocrinol Metab. 2016 Mar 22;:jc20161133 Authors: Rohde U, Sonne DP, Christensen M, Hansen M, Brønden A, Toräng S, Rehfeld JF, Holst JJ, Vilsbøll T, Knop FK Abstract CONTEXT: Bile acids have been suggested to mediate glucagon-like peptide-1 (GLP-1) secretion via activation of the bile acid receptor TGR5 on enteroendocrine L cells. Metformin too has been shown to increase GLP-1 levels. The effect of gallbladder emptying, metformin or a combination has ... περισσότερα »
Why I’ll never cook again after cancer battle says top chef – Yorkshire Post
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 57 δευτερόλεπτα
Yorkshire Post Why I’ll never cook again after cancer battle says top chef Yorkshire Post But then last summer Tim was told the devastating news that the cancer had spread to his saliva glands and he was forced to take a break from the restaurant that had been his life. “It was really hard for […]
First Morning Voided Urinary Gonadotropin Measurements as an Alternative to the GnRH Test
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 57 δευτερόλεπτα
Aims: We studied whether first morning voided (FMV) urinary gonadotropin measurements could be used as a noninvasive alternative to the GnRH test in the assessment of the hypothalamic-pituitary-gonadal function in children. Methods: In a single-center study, we compared FMV urinary gonadotropin concentrations with basal and GnRH-stimulated serum gonadotropin levels in 274 children and adolescents (78 […]
NHS Lothian admits mouth cancer specialist shortage – BBC News
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 57 δευτερόλεπτα
BBC News NHS Lothian admits mouth cancer specialist shortage BBC News She said: «My dentist noticed white patches on the inside of my cheeks and under my tongue during a check-up. «I hadn’t noticed the patches and the dentist said because they were unusual he would refer me to the dental institute to get checked […]
Genetic characterization of the complete genome of an Aleutian mink disease virus isolated in north China
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 57 δευτερόλεπτα
Abstract The genome of a highly pathogenic strain of Aleutian disease mink virus (AMDV-BJ) isolated from a domestic farm in North China has been determined and compared with other strains. Alignment analysis of the major structural protein VP2 revealed that AMDV-BJ is unique among 17 other AMDV strains. Compared with the nonpathogenic strain ADV-G, the […]
JDB, Vol. 4, Pages 14: Hox Genes in Cardiovascular Development and Diseases
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 57 δευτερόλεπτα
Congenital heart defects (CHD) are the leading cause of death in the first year of life. Over the past 20 years, much effort has been focused on unraveling the genetic bases of CHD. In particular, studies in human genetics coupled with those of model organisms have provided valuable insights into the gene regulatory networks underlying […]
Prevalence of Skin and Skin-Related Diseases in the Rochester Epidemiology Project and a Comparison with Other Published Prevalence Studies
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 57 δευτερόλεπτα
In Olmsted County, Minn., USA, reliable, population-based epidemiologic research studies can be performed because of a unique medical records linkage system, the Rochester Epidemiology Project (REP). Our objective was to summarize the epidemiologic data describing the prevalence of skin and skin-related diseases derived from the REP and to compare the findings with those from other […]
Halitosis, an imperative constraint in measuring the outcome of the oral care in oncology patients.
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 57 δευτερόλεπτα
Halitosis, an imperative constraint in measuring the outcome of the oral care in oncology patients. Oral Oncol. 2016 Mar 19; Authors: Satheeshkumar PS, Mohan MP PMID: 27004697 [PubMed – as supplied by publisher] from #AlexandrosSfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1LJt1eG via IFTTT
Solar Radiation Received by Slopes Using COMS Imagery, a Physically Based Radiation Model, and GLOBE
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 57 δευτερόλεπτα
This study mapped the solar radiation received by slopes for all of Korea, including areas that are not measured by ground station measurements, through using satellites and topographical data. When estimating insolation with satellite, we used a physical model to measure the amount of hourly based solar surface insolation. Furthermore, we also considered the effects […]
Design and Performance Evaluation of a Solar Assisted Heat Pump Dryer Integrated with Biomass Furnace for Red Chilli
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 57 δευτερόλεπτα
The performance of a solar assisted heat pump dryer integrated with biomass furnace has been designed and evaluated for drying red chillies, and drying kinetics of red chillies were evaluated. The red chillies were dried from 22 kg with moisture content of 4.26 db to moisture content of 0.08 db which needed 11 hours, with the average drying […]
“Negotiorum Gestio” in Family Medicine, Informed Consent Obtainment, and Disciplinary Responsibility
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 57 δευτερόλεπτα
Introduction. Negotiorum gestio (NG) denotes an action where a person well intendedly acts on behalf of another without obtaining the latter’s prior consent. In broad terms, NG-like actions have played a considerable role in health care provision. In some settings, health care delivery with only little or presumed patients’ consent has been the rule rather […]
Cost-effectiveness analysis of papillary thyroid cancer surveillance.
[image: http:--media.wiley.com-assets-7315-19-Wi] Related Articles *Cost-effectiveness analysis of papillary thyroid cancer surveillance.* Cancer. 2015 Dec 1;121(23):4132-40 Authors: Wang LY, Roman BR, Migliacci JC, Palmer FL, Tuttle RM, Shaha AR, Shah JP, Patel SG, Ganly I Abstract BACKGROUND: The recent overdiagnosis of subclinical, low-risk papillary thyroid cancer (PTC) coincides with a growing national interest in cost-effective health care practices. The aim of this study was to measure the relative cost-effectiveness of disease surveillance of low-risk PTC patients versus ... περισσότερα »
Maternal Iodine Exposure: A Case of Fetal Goiter and Neonatal Hearing Loss.
*Maternal Iodine Exposure: A Case of Fetal Goiter and Neonatal Hearing Loss.* Pediatrics. 2016 Mar 22; Authors: Overcash RT, Marc-Aurele KL, Hull AD, Ramos GA Abstract A 27-year-old gravid 1 at 27 weeks 6 days with a history of hypothyroidism had an ultrasound that demonstrated a 3.9 × 3.2 × 3.3-cm well-circumscribed anterior neck mass, an extended fetal head, and polyhydramnios. Further characterization by magnetic resonance imaging (MRI) showed a fetal goiter. During her evaluation for the underlying cause of the fetal goiter, the patient revealed she was taking nutritional iod...περισσότερα »
Railway suicide in England and Wales 2000–2013: a time-trends analysis
BMC Public Health from Emergency Medicine via ola Kala on Inoreader http://ift.tt/1ZvpYJ6 via IFTTT
A combination of three-dimensional printing and computer-assisted virtual surgical procedure for preoperative planning of acetabular fracture reduction
Injury from Emergency Medicine via ola Kala on Inoreader http://ift.tt/1RivHA8 via IFTTT
The utility of bolus IV nicardipine for hypertensive emergencies in the emergency department
The American Journal of Emergency Medicine from Emergency Medicine via ola Kala on Inoreader http://ift.tt/1Zvq03Q via IFTTT
Telemedicine provides non-inferior research informed consent for remote study enrollment: a randomized controlled trial
Academic Emergency Medicine from Emergency Medicine via ola Kala on Inoreader http://ift.tt/1RivFs5 via IFTTT
Traumatic injuries among adult obese patients in southern Taiwan: a cross-sectional study based on a trauma registry system
BMC Public Health from Emergency Medicine via ola Kala on Inoreader http://ift.tt/1ZvpYsx via IFTTT
The experience of emotional wellbeing for patients with physical injury: A qualitative follow up study
Injury from Emergency Medicine via ola Kala on Inoreader http://ift.tt/1RivHA0 via IFTTT
Postpartum Contraception: An exploratory study of lactation consultants’ knowledge and practices
Contraception from Emergency Medicine via ola Kala on Inoreader http://ift.tt/1Zvq03D via IFTTT
Point of care testing for group A streptococci in patients presenting with pharyngitis will improve appropriate antibiotic prescription
Emergency Medicine Australasia from Emergency Medicine via ola Kala on Inoreader http://ift.tt/1RivFs0 via IFTTT
Lack of agreement on distal radius fracture treatment
Journal of the American Board of Family Medicine from Emergency Medicine via ola Kala on Inoreader http://ift.tt/1ZvpZNk via IFTTT
Effective treatment of gastrointestinal bleeding with thalidomide - Chances and limitations
World Journal of Gastroenterology from Emergency Medicine via ola Kala on Inoreader http://ift.tt/1RivHjG via IFTTT
Stabilisation of infected peri-articular nonunions with an antibiotic impregnated cement coated locking plate: Technique and indications
Injury from Emergency Medicine via ola Kala on Inoreader http://ift.tt/1ZvpYc8 via IFTTT
Occupational fatalities among young workers in the United States: 2001–2012
American Journal of Industrial Medicine from Emergency Medicine via ola Kala on Inoreader http://ift.tt/1RivFbB via IFTTT
Does Routine Midazolam Administration Prior to Nasogastric Tube Insertion in the Emergency Department Decreases Patients’ Pain? (a Pilot Study)
Academic Emergency Medicine from Emergency Medicine via ola Kala on Inoreader http://ift.tt/1ZvpWRH via IFTTT
Craniofacial disorders associated with airway obstruction in the neonate
Seminars in Fetal and Neonatal Medicine from Emergency Medicine via ola Kala on Inoreader http://ift.tt/1RivHjv via IFTTT
Long-Term Stability of Motor Cortical Activity: Implications for Brain Machine Interfaces and Optimal Feedback Control
The human motor system is capable of remarkably precise control of movements—consider the skill of professional baseball pitchers or surgeons. This precise control relies upon stable representations of movements in the brain. Here, we investigated the stability of cortical activity at multiple spatial and temporal scales by recording local field potentials (LFPs) and action potentials (multiunit spikes, MSPs) while two monkeys controlled a cursor either with their hand or directly from the brain using a brain–machine interface. LFPs and some MSPs were remarkably stable over time p... περισσότερα »
Chewing efficiency, bite force and oral health-related quality of life with narrow diameter implants - a prospective clinical study: results after one year
[image: cover.gif?v=1&s=87bf4a525ec3ddfbe594c784] Abstract Objective This prospective study aimed to investigate the evolution of chewing efficiency, maximum voluntary bite force (MBF) and oral health-related quality of life (OHRQoL) in edentulous patients treated with narrow diameter implants (NDIs) over the course of 1 year. Materials and Methods Four NDIs (MDI®, 3M ESPE, diameter 1.8 mm) were placed interforaminally in 20 edentulous patients. They were immediately loaded by converting the existing prosthesis into an implant overdenture. Participants were examined six times p...περισσότερα »
Challenges in HIV persistent viral replication regardless of potent antiretroviral therapy
Abstract Though nowadays combined antiretroviral treatment (cART) is effective at suppressing viral replication to below the detection limits of plasma HIV-1 RNA assays, it is not yet considered a curative therapy, because HIV-1 continues to replicate in the so called viral reservoirs (Riddler et al, 2016; Sahu 2015; Barouch and Deeks 2014). Treated HIV-patients need to continue life-long therapy; otherwise, after stopping therapy, most patients will experience a rebound in plasma virus (Kearney et al, 2015). This article is protected by copyright. All rights reserved. from #ORL-... περισσότερα »
Astrocytes Regulate GLP-1 Receptor-Mediated Effects on Energy Balance
Astrocytes are well established modulators of extracellular glutamate, but their direct influence on energy balance-relevant behaviors is largely understudied. As the anorectic effects of glucagon-like peptide-1 receptor (GLP-1R) agonists are partly mediated by central modulation of glutamatergic signaling, we tested the hypothesis that astrocytic GLP-1R signaling regulates energy balance in rats. Central or peripheral administration of a fluorophore-labeled GLP-1R agonist, exendin-4, localizes within astrocytes and neurons in the nucleus tractus solitarius (NTS), a hindbrain nucl... περισσότερα »
H3K9me3 Inhibition Improves Memory, Promotes Spine Formation, and Increases BDNF Levels in the Aged Hippocampus
An increasing number of studies show that an altered epigenetic landscape may cause impairments in regulation of learning and memory-related genes within the aged hippocampus, eventually resulting in cognitive deficits in the aged brain. One such epigenetic repressive mark is trimethylation of H3K9 (H3K9me3), which is typically implicated in gene silencing. Here, we identify, for the first time, an essential role for H3K9me3 and its histone methyl transferase (SUV39H1) in mediating hippocampal memory functions. Pharmacological inhibition of SUV39H1 using a novel and selective inhib... περισσότερα »
Comparison of Matching Pursuit Algorithm with Other Signal Processing Techniques for Computation of the Time-Frequency Power Spectrum of Brain Signals
Signals recorded from the brain often show rhythmic patterns at different frequencies, which are tightly coupled to the external stimuli as well as the internal state of the subject. In addition, these signals have very transient structures related to spiking or sudden onset of a stimulus, which have durations not exceeding tens of milliseconds. Further, brain signals are highly nonstationary because both behavioral state and external stimuli can change on a short time scale. It is therefore essential to study brain signals using techniques that can represent both rhythmic and tra... περισσότερα »
Complex Multiplexing of Reward-Cue- and Licking-Movement-Related Activity in Single Midline Thalamus Neurons
Midline thalamus is implicated in linking visceral and exteroceptive sensory information with behavior. However, whether neuronal activity is modulated with temporal precision by cues and actions in real time is unknown. Using single-neuron recording and a Pavlovian visual-cue/liquid-reward association task in rats, we discovered phasic responses to sensory cues, appropriately timed to modify information processing in output targets, as well as tonic modulations within and between trials that were differentially reward modulated, which may have distinct arousal functions. Many of ... περισσότερα »
Inhibitor-2 In Vivo Enhances Protein Phosphatase-1 Activity and Suppresses Learning and Memory: Possible Implication for the Progression of Tau Pathology
from #ORL-Sfakianakis via xlomafota13 on Inoreader http://ift.tt/1Uc5x4A via IFTTT
Deletion of Vax1 from Gonadotropin-Releasing Hormone (GnRH) Neurons Abolishes GnRH Expression and Leads to Hypogonadism and Infertility
Hypothalamic gonadotropin-releasing hormone (GnRH) neurons are at the apex of the hypothalamic-pituitary-gonadal axis that regulates mammalian fertility. Herein we demonstrate a critical role for the homeodomain transcription factor ventral anterior homeobox 1 (VAX1) in GnRH neuron maturation and show that *Vax1* deletion from GnRH neurons leads to complete infertility in males and females. Specifically, global *Vax1* knock-out embryos had normal numbers of GnRH neurons at 13 d of gestation, but no GnRH staining was detected by embryonic day 17. To identify the role of VAX1 specif...περισσότερα »
Heterogeneous Responses of Tonically Active Interneurons in the Dorsal Striatum
from #ORL-Sfakianakis via xlomafota13 on Inoreader http://ift.tt/1pzS6Oz via IFTTT
Iron Level and Myelin Content in the Ventral Striatum Predict Memory Performance in the Aging Brain
Age-related memory impairments have been associated with structural changes in the dopaminergic system, but the underlying mechanisms remain unclear. Recent work indicates that iron accumulation might be of particular relevance. As iron accumulates, a degeneration of myelin sheaths has been observed in the elderly, but the relationship between both and their impact on memory performance in healthy elderly humans remain important open questions. To address this issue, we combined an established behavioral paradigm to test memory performance [verbal learning memory test (VLMT)] with...περισσότερα »
Deletion of Vax1 from Gonadotropin-Releasing Hormone (GnRH) Neurons Abolishes GnRH Expression and Leads to Hypogonadism and Infertility
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Hypothalamic gonadotropin-releasing hormone (GnRH) neurons are at the apex of the hypothalamic-pituitary-gonadal axis that regulates mammalian fertility. Herein we demonstrate a critical role for the homeodomain transcription factor ventral anterior homeobox 1 (VAX1) in GnRH neuron maturation and show that Vax1 deletion from GnRH neurons leads to complete infertility in males and females. Specifically, global […]
Clinicopathological analysis of salivary gland tissue from patients with IgG4-related disease.
*Clinicopathological analysis of salivary gland tissue from patients with IgG4-related disease.* Acta Otolaryngol. 2016 Mar 23;:1-5 Authors: Takano K, Nomura K, Abe A, Kamekura R, Yamamoto M, Ichimiya S, Takahashi H, Himi T Abstract Conclusion The diagnosis of immunoglobulin G4-related disease (IgG4-RD) should be based on the morphology of tissue biopsy, and this study recommends a submandibular gland (SMG) biopsy for accurate diagnosis and to exclude malignant disease. Objective To clarify which type of biopsy specimen (SMG or labial salivary gland [LSG]) should be taken from pa...περισσότερα »
T-status and an oral fluoropyrimidine, S-1, adjuvant chemotherapy are prognostic factors in reduced-RADPLAT for resectable hypopharyngeal cancer.
*T-status and an oral fluoropyrimidine, S-1, adjuvant chemotherapy are prognostic factors in reduced-RADPLAT for resectable hypopharyngeal cancer.* Acta Otolaryngol. 2016 Mar 23;:1-7 Authors: Wakisaka N, Hirai N, Kondo S, Aga M, Nakanishi Y, Tsuji A, Endo K, Murono S, Yoshizaki T Abstract CONCLUSION: Reduced-RADPLAT for HPC achieved comparative survival and locoregional control rates with lower toxicities compared with concurrent chemoradiotherapies including original RADPLAT. S-1 adjuvant chemotherapy showed a survival benefit. OBJECTIVES: To evaluate the efficacy and toxicities ... περισσότερα »
Detection of pneumolabyrinth after temporal bone trauma using computed tomography.
*Detection of pneumolabyrinth after temporal bone trauma using computed tomography.* Acta Otolaryngol. 2016 Mar 23;:1-5 Authors: Choi JW, Lyu AR, Ryu KA, Kim D, Park YH Abstract CONCLUSION: Pneumolabyrinth is a very rare condition, even in otic capsule disrupting (OCD) fracture. Hearing was not always impaired, even in cases with OCD fracture. The co-existence of pneumocochlea, regarded as a risk factor for total hearing loss, was extremely rare in cases of pneumolabyrinth. OBJECTIVES: The purposes of this study were to analyze the radiological and clinical features in patients w... περισσότερα »
Are corticosteroids useful in all degrees of severity and rapid recovery of Bell's palsy?
*Are corticosteroids useful in all degrees of severity and rapid recovery of Bell's palsy?* Acta Otolaryngol. 2016 Mar 22;:1-6 Authors: Ferreira M, Firmino MJ, Marques EA, Santos PC, Duarte JA Abstract Conclusions The results provide preliminary evidence that corticosteroids were not effective in all grades of dysfunction and for achieving a rapid remission in the early phase of BP, highlighting the need to define standard and rigorous criteria to prescribe corticosteroids in these patients. Objectives The main aim of this study was to investigate whether the use of corticosteroi... περισσότερα »
Chewing efficiency, bite force and oral health-related quality of life with narrow diameter implants - a prospective clinical study: results after one year
[image: cover.gif?v=1&s=87bf4a525ec3ddfbe594c784] Abstract Objective This prospective study aimed to investigate the evolution of chewing efficiency, maximum voluntary bite force (MBF) and oral health-related quality of life (OHRQoL) in edentulous patients treated with narrow diameter implants (NDIs) over the course of 1 year. Materials and Methods Four NDIs (MDI®, 3M ESPE, diameter 1.8 mm) were placed interforaminally in 20 edentulous patients. They were immediately loaded by converting the existing prosthesis into an implant overdenture. Participants were examined six times p...περισσότερα »
Challenges in HIV persistent viral replication regardless of potent antiretroviral therapy
Abstract Though nowadays combined antiretroviral treatment (cART) is effective at suppressing viral replication to below the detection limits of plasma HIV-1 RNA assays, it is not yet considered a curative therapy, because HIV-1 continues to replicate in the so called viral reservoirs (Riddler et al, 2016; Sahu 2015; Barouch and Deeks 2014). Treated HIV-patients need to continue life-long therapy; otherwise, after stopping therapy, most patients will experience a rebound in plasma virus (Kearney et al, 2015). This article is protected by copyright. All rights reserved. from #Γναθ... περισσότερα »
Aims & Scope/Editorial board
Publication date: June 2016 *Source:*Archives of Oral Biology, Volume 66 from #Dental via xlomafota13 on Inoreader http://ift.tt/1ME5FSx via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
Passive immunization with HIV-1–neutralizing antibodies: Is it effective and safe?
Abstract Human immunodeficiency virus type 1 (HIV-1) infection, along with HIV-2 the cause of acquired immunodeficiency syndrome (AIDS), has been a global health problem for more than three decades (Sharp and Hahn 2011). A recent report from UNAIDS indicated that an estimated 35 million people were living with HIV-1 worldwide and 2.1 million became newly infected (UNAIDS, 2014). Antiretroviral therapy (ART) is a current treatment for HIV-1 infection (Hammer et al, 2008). ART can suppress HIV-1 replication and reduce the morbidity and mortality rate in HIV/AIDS patients. However, it... περισσότερα »
Pre-treatment anxiety in a dental hygiene recall population: a cross-sectional pilot study
Abstract Background Increased levels of anxiety may affect a patient's receptiveness to treatment, health care information and behaviour modification. This study was undertaken to assess pre-treatment anxiety in a dental hygiene recall population maintaining a schedule of regular preventive care appointments. Methods The sample population consisted of 46 consecutive adult recall patients waiting for their regularly scheduled dental hygiene appointment. Pre-treatment state (current) anxiety was assessed using the State-Trait-Anxiety Inventory (STAI), State form; dental anxiety wit... περισσότερα »
Aims & Scope/Editorial board
Publication date: June 2016 *Source:*Archives of Oral Biology, Volume 66 from #ΓναθοΧειρουργική via xlomafota13 on Inoreader http://ift.tt/1ME5FSx via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
Antibacterial effect of silver (I) carbohydrate complexes on oral pathogenic key species in vitro
Abstract Background It was the aim of this study to evaluate the antibacterial impact of two silver(I) carbohydrate complexes with tripodal thioglycosides, namely tris[2-(β-D-thio-glucopyranosyl)ethyl]-amine-silver(I)-nitrate (*3*) and tris[2-(α-D-thio-manno-pyranosyl)ethyl]-amine-silver(I)-nitrate (*4*), on five oral pathogenic bacterial strains. Furthermore, cytocompatibility was tested using human gingival fibroblasts (HGF). Methods Minimum inhibitory concentrations (MIC) were determined on five oral pathogenic bacterial strains by using the broth microdilution method: Fusobac... περισσότερα »
Relationship between body mass index and functional recovery in stroke rehabilitation setting.
*Relationship between body mass index and functional recovery in stroke rehabilitation setting.* Disabil Rehabil. 2016 Mar 23;:1-2 Authors: Nishioka S, Maeda K, Wakabayashi H, Shamoto H PMID: 27008207 [PubMed - as supplied by publisher] from Swallowing and Swallowing Disorders (Dysphagia) via a.lsfakia on Inoreader http://ift.tt/1Uc6xFD via IFTTT
Post-stroke dysphagia: A review and design considerations for future trials.
*Post-stroke dysphagia: A review and design considerations for future trials.* Int J Stroke. 2016 Mar 22; Authors: Cohen DL, Roffe C, Beavan J, Blackett B, Fairfield CA, Hamdy S, Havard D, McFarlane M, McLauglin C, Randall M, Robson K, Scutt P, Smith C, Smithard D, Sprigg N, Warusevitane A, Watkins C, Woodhouse L, Bath PM Abstract Post-stroke dysphagia (a difficulty in swallowing after a stroke) is a common and expensive complication of acute stroke and is associated with increased mortality, morbidity, and institutionalization due in part to aspiration, pneumonia, and malnutriti... περισσότερα »
Medical marijuana use in head and neck squamous cell carcinoma patients treated with radiotherapy.
*Medical marijuana use in head and neck squamous cell carcinoma patients treated with radiotherapy.* Support Care Cancer. 2016 Mar 23; Authors: Elliott DA, Nabavizadeh N, Romer JL, Chen Y, Holland JM Abstract PURPOSE: The purpose of the study was to better understand why patients with history of head and neck cancer (HNC) treated with radiotherapy are using medical marijuana (MM). METHODS: Established HNC quality of life questionnaires and our own MM quality of life questionnaire were sent to 15 HNC patients treated at our institution who reported using MM. Patients are clinically... περισσότερα »
Strategies of laparoscopic thyroidectomy for treatment of substernal goiter via areola approach.
*Strategies of laparoscopic thyroidectomy for treatment of substernal goiter via areola approach.* Surg Endosc. 2016 Mar 22; Authors: Wang C, Sun P, Li J, Yang W, Yang J, Feng Z, Cao G, Lee S Abstract BACKGROUND: This study was aimed at exploring the feasibility and strategies of laparoscopic thyroidectomy for treatment of substernal goiter via areola approach. METHODS: A retrospective analysis was conducted to investigate 15 cases of laparoscopic resection of substernal goiter via the areola approach (laparoscopic group) and 12 cases of open resection of substernal goiter via lo...περισσότερα »
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