Gentamicin Treatment Prior to Schwannoma Surgery - No Residual Function
Gentamicin Treatment Prior to Schwannoma Surgery -
No Residual Function: *Condition*: Vestibular Schwannoma*Intervention*:
Drug: Gentamicin*Sponsor*: Lund UniversityArmsAssigned Interventions
Experimental: Gentamicin treatedInstallation of gentamicin in the middle ear 6
weeks prior to surgery + rehabilitation exercises before and after both
treatment and surgery.Rehabilitation exercises are not considered to be an
intervention since their benign impact on vestibular/postural compensation is
well documented and exclusion from exercises would not be approved by the
ethical...περισσότερα »
A Web-Based Multimedia Intervention for Head and Neck Cancer Patients
A Web-Based Multimedia Intervention for Head and
Neck Cancer Patients: *Condition*: Cancer of the Head and Neck*Intervention*:
Behavioral: My Journey AHead*Sponsor*: Fox Chase Cancer CenterArmsAssigned
InterventionsExperimental: My Journey AHeadSeveral internet modules will be
developed to address mouth and swallowing concerns, oral care, healthy eating,
speech problems, coping with cancer, pain management, and physical therapy.
Behavioral: My Journey AHeadThe intervention program will contain information
and interactive activities around swallowing concerns, proper ora...περισσότερα »
Donafenib Monotherapy for Previously Treated Metastatic Nasopharyngeal Carcinoma
Donafenib Monotherapy for Previously Treated
Metastatic Nasopharyngeal Carcinoma: *Condition*: Nasopharyngeal Carcinoma
*Intervention*: Drug: Donafenib*Sponsor*: Suzhou Zelgen Biopharmaceuticals
Co.,LtdArmsAssigned InterventionsExperimental: Donafeinibdonafenib 200mg,bid
Drug: Donafenibdonafenib 200mg，bidOther Name: CM4307Detailed Description:The
study is an open-label, phase 1B study recruiting 18 patients. Patients were
eligible to participate when they have histological or cytological documentation
of the nasopharyngeal carcinoma. They must have received locally a...περισσότερα »
Association between Electronic Cigarette Use and Asthma
Association between Electronic Cigarette Use and
Asthma among High School Students in South Korea: by Jun Ho Cho, Samuel Y. Paik
Objectives Little is known about health outcomes related to electronic cigarette
(EC) use, despite its growing popularity. The aim of this study is to
investigate the association between EC use and asthma.Methods The study design
is a cross-sectional study. A total of 35,904 high school students were included
as the final study population. The presence of asthma was based on a student’s
self-reported doctor diagnosis of asthma in the past 12 months....περισσότερα »
Effect of Nasal Obstruction on Continuous Positive Airway Pressure Treatment: Computational Fluid Dynamics Analyses
Effect of Nasal Obstruction on Continuous Positive
Airway Pressure Treatment: Computational Fluid Dynamics Analyses: by Tadashi
Wakayama, Masaaki Suzuki, Tadashi TanumaObjective Nasal obstruction is a common
problem in continuous positive airway pressure (CPAP) therapy for obstructive
sleep apnea and limits treatment compliance. The purpose of this study is to
model the effects of nasal obstruction on airflow parameters under CPAP using
computational fluid dynamics (CFD), and to clarify quantitatively the relation
between airflow velocity and pressure loss coefficient in subject...περισσότερα »
Facial palsy : Aggressive osteoblastoma of the temporal bone
*: an unusual cause of facial palsy**via
ScienceDirect Publication: Brazilian Journal of Otorhinolaryngology*Introduction
*Osteoblastoma was first described in 1956 by Lichenstein and Jaffe.1 and 2 It
represents 0.8–1% of all bone tumors and affects young adults, with male
preponderance.3 It predominantly affects the axial skeleton and vertebrae with
only 14–20% of tumors affecting the skull. The most commonly affected sites are
maxilla, temporal, sphenoid, occipital, ethmoid and frontal bones.
Histologically it is a benign, vascular, osteoblastic tumor with variable
osteoid mineral...περισσότερα »
Intranasal splinting on bacterial colonization, postoperative complications, and patient discomfort after septoplasty operations
The effects of the time of via ScienceDirect
Publication: Brazilian Journal of Otorhinolaryngology*Source:*Brazilian Journal
of OtorhinolaryngologyAuthor(s): Abdullah Karatas, Filiz Pehlivanoglu, Mehti
Salviz, Nuray Kuvat, Isil Taylan Cebi, Burak Dikmen, Gonul SengozIntroductionThe
main reason for nasal tampon placement after septoplasty is to prevent
postoperative hemorrhage, while the secondary purpose is internal stabilization
after operations involving the cartilaginous-bony skeleton of the nose. Silicone
intranasal splints are as successful as other materials in controlling
p...περισσότερα »
Bilateral parotid glands infection caused by Calmette–Guerin Bacillus after intravesical therapy for recurrent bladder cancer
*: a case report**via ScienceDirect
Publication: Brazilian Journal of Otorhinolaryngology*Introduction*The
Calmette–Guerin Bacillus (BCG), an attenuated live strain of Mycobacterium
boviswas originally developed by Albert Leon Charles Calmette and Camile Guerin
in 1925 as a vaccine for tuberculosis. At the present, BCG is widely used as a
complementary therapy for superficial bladder neoplasms. This treatment is
considered to be safe and well tolerated although local and distal complications
may appear. 1 In 2003, Diaz et al. reported in the Spanish language, for the
first time, a ...περισσότερα »
Reviving virus based cancer vaccines by using cytomegalovirus vectors expressing modified tumor antigens.
*Reviving virus based cancer vaccines by using
cytomegalovirus vectors expressing modified tumor antigens.*Oncoimmunology.
2016;5(1):e1056974Authors: Qiu Z, Grenier JM, Khanna KMAbstractCancer vaccines
that have utilized various immunization strategies to induce antitumor immunity
have largely failed in clinical settings. We have recently developed a cancer
vaccine using a cytomegalovirus (CMV) based vector that expressed a modified
melanoma antigen that elicited a robust antitumor CD8(+) T cell response and
tumor rejection.PMID: 26942064 [PubMed - as supplied by publisher]...περισσότερα »
Density of tumor-infiltrating lymphocytes correlates with extent of brain edema and overall survival time in patients with brain metastases.
*Density of tumor-infiltrating lymphocytes
correlates with extent of brain edema and overall survival time in patients with
brain metastases.*Oncoimmunology. 2016;5(1):e1057388Authors: Berghoff AS, Fuchs
E, Ricken G, Mlecnik B, Bindea G, Spanberger T, Hackl M, Widhalm G, Dieckmann K,
Prayer D, Bilocq A, Heinzl H, Zielinski C, Bartsch R, Birner P, Galon J,
Preusser MAbstractThe immune microenvironment of the brain differs from that of
other organs and the role of tumor-infiltrating lymphocytes (TILs) in brain
metastases (BM), one of the most common and devastating complication
...περισσότερα »
Favorable overall survival in stage III melanoma patients after adjuvant dendritic cell vaccination.
*Favorable overall survival in stage III melanoma
patients after adjuvant dendritic cell vaccination.*Oncoimmunology.
2016;5(1):e1057673Authors: Bol KF, Aarntzen EH, Hout FE, Schreibelt G, Creemers
JH, Lesterhuis WJ, Gerritsen WR, Grunhagen DJ, Verhoef C, Punt CJ, Bonenkamp JJ,
de Wilt JH, Figdor CG, de Vries IJAbstractMelanoma patients with regional
metastatic disease are at high risk for recurrence and metastatic disease,
despite radical lymph node dissection (RLND). We investigated the immunologic
response and clinical outcome to adjuvant dendritic cell (DC) vaccination
in...περισσότερα »
Long-lasting multifunctional CD8(+) T cell responses in end-stage melanoma patients can be induced by dendritic cell vaccination.
*Long-lasting multifunctional CD8(+) T cell
responses in end-stage melanoma patients can be induced by dendritic cell
vaccination.*Oncoimmunology. 2016;5(1):e1067745Authors: Wimmers F, Aarntzen EH,
Duiveman-deBoer T, Figdor CG, Jacobs JF, Tel J, de Vries IJAbstractCytotoxic T
cells are considered crucial for antitumor immunity and their induction is the
aim of various immunotherapeutic strategies. High frequencies of tumor-specific
CD8(+) T cells alone, however, are no guarantee for long-term tumor control.
Here, we analyzed the functionality of tumor-specific CD8(+) T cells
...περισσότερα »
Targeting TNF alpha as a novel strategy to enhance CD8(+) T cell-dependent immune response in melanoma?
*Targeting TNF alpha as a novel strategy to enhance
CD8(+) T cell-dependent immune response in melanoma?*Oncoimmunology.
2016;5(1):e1068495Authors: Bertrand F, Rochotte J, Colacios C, Montfort A,
Andrieu-Abadie N, Levade T, Benoist H, Ségui BAbstractTumor Necrosis Factor α
(TNF) is a pleiotropic cytokine exhibiting a dual activity in oncoimmunology,
either acting as a cytotoxic effector produced by leukocytes or behaving as an
immunosuppressive molecule. We have just discovered that TNF signaling impairs
the accumulation of tumor-infiltrating CD8(+) T lymphocytes in
experimen...περισσότερα »
The extent to which melanoma alters tissue-resident dendritic cell function correlates with tumorigenicity.
*The extent to which melanoma alters
tissue-resident dendritic cell function correlates with tumorigenicity.*
Oncoimmunology. 2016;5(1):e1069462Authors: Hargadon KMAbstractWe have shown that
melanoma-derived factors alter the function of differentiated tissue-resident
dendritic cells (DC) in a tumorigenicity-dependent manner. Soluble factors,
including TGFβ1 and VEGF-A, contributed to dendritic cell dysfunction associated
with a highly-aggressive melanoma and conferred a phenotype upon DC likely to
favor immune escape and tumor outgrowth.PMID: 26942090 [PubMed - as supplied
...περισσότερα »
PD-1 expression conditions T cell avidity within an antigen-specific repertoire.
*PD-1 expression conditions T cell avidity within
an antigen-specific repertoire.*Oncoimmunology. 2016;5(1):e1104448Authors: Simon
S, Vignard V, Florenceau L, Dreno B, Khammari A, Lang F, Labarriere NAbstract
Despite its negative regulatory role on tumor-specific T cells, Programmed cell
death 1 (PD-1) is also a marker of activated tumor-infiltrating T cells. In
cancer, PD-1 blockade partially reverses T cell dysfunction allowing the
amplification of tumor reactive T cells. Here, we investigated the role of PD-1
signaling on effector/memory human T cells specific for shared m...περισσότερα »
Middle turbinate angiofibroma
*: an unusual location for juvenile
angiofibroma**via ScienceDirect Publication: Brazilian Journal of
Otorhinolaryngology*Introduction*Angiofibromas are the most frequently
encountered histologically benign but potentially locally destructive vascular
tumors that generally originate from the posterior lateral wall of the
nasopharynx. These neoplasms are typically found in adolescent males and rarely
seen after 25 years of age.1 Angiofibromas located in extranasopharyngeal sites
are uncommon, and sporadically reported in the literature. In this article, we
present a very rare case, ...περισσότερα »
Iatrogenic nasal vestibular stenosis after maxillofacial reconstructive surgery
*Iatrogenic nasal vestibular stenosis after
maxillofacial reconstructive surgery**via ScienceDirect Publication: Brazilian
Journal of Otorhinolaryngology*Introduction*Nasal vestibular stenosis is not
only an esthetic, but also a functional problem for the patient.1 It is caused
by disruption of the nasal vestibular lining with secondary proliferation of
granulation and fibrous tissue.1 and 2 Various causes account for the
development of nasal vestibular stenosis, including trauma, infection, and
iatrogenic injury to the vestibular skin. Although a number of techniques have
been des...περισσότερα »
Otologic and audiologic characteristics of type 2 diabetics
in a tertiary health institution in Nigeriavia
ScienceDirect Publication: Brazilian Journal of Otorhinolaryngology
*Source:*Brazilian Journal of OtorhinolaryngologyAuthor(s): Stephen Oluwatosin
Adebola, Micheal A. Olamoyegun, Olusola A. Sogebi, Sandra O. Iwuala, John A.
Babarinde, Abayomi O. OyelakinIntroductionThis cross-sectional comparative study
was carried out at the Diabetes outpatient clinic of LAUTECH Teaching Hospital
(LTH) Ogbomoso, Nigeria.ObjectivesThis study assessed patterns of otologic
diseases and auditory acuity among type 2 diabetics and determinants of these
find...περισσότερα »
Former Brazilian leader Lula is implicated in huge corruption probe – The Japan Times
sfakianakisdiseasesστοHuman Diseases
Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete
72100,Greece,tel :00302841026182 & 00306932607174Πριν από 12
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The Japan Times Former Brazilian leader Lula
is implicated in huge corruption probe The Japan Times SAO PAULO – Luiz Inacio
Lula da Silva, a former metalworker who rose to become one of the most popular
presidents in Brazilian history, now sees his legacy under threat after being
implicated in a huge corruption probe. Lula, […]
Integration of HIV Care into Community Management of Acute Childhood Malnutrition Permits Good Outcomes: Retrospective Analysis of Three Years of a Programme in Lusaka
sfakianakisdiseasesστοHuman Diseases
Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete
72100,Greece,tel :00302841026182 & 00306932607174Πριν από 12
δευτερόλεπτα
by Beatrice Amadi, Mercy Imikendu, Milika
Sakala, Rosemary Banda, Paul Kelly Background While HIV has had a major impact
on health care in southern Africa, there are few data on its impact on acute
malnutrition in children in the community. We report an analysis of outcomes in
a large programme of community management of acute […]
PI-3K Inhibitors Preferentially Target CD15+ Cancer Stem Cell Population in SHH Driven Medulloblastoma
sfakianakisdiseasesστοHuman Diseases
Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete
72100,Greece,tel :00302841026182 & 00306932607174Πριν από 12
δευτερόλεπτα
by Alok R. Singh, Shweta Joshi, Muamera
Zulcic, Michael Alcaraz, Joseph R. Garlich, Guillermo A. Morales, Yoon J. Cho,
Lei Bao, Michael L. Levy, Robert Newbury, Denise Malicki, Karen Messer, John
Crawford, Donald L. Durden Sonic hedgehog (SHH) medulloblastoma (MB) subtype is
driven by a proliferative CD15+ tumor propagating cell (TPC), also considered in
the […]
Sneaker Alert! – The Swazi Observer
sfakianakisdiseasesστοHuman Diseases
Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete
72100,Greece,tel :00302841026182 & 00306932607174Πριν από 12
δευτερόλεπτα
The Swazi Observer Sneaker Alert! The Swazi
Observer Rudolf passed on in 1974 of lung cancer, and his son ran the company.
In 1989, Armin and … It was the first shoe to have an internal inflation
mechanism that regulated a unique fitting cushion in the lower and upper tongue
to provide locking around … […]
Association of tinnitus and hearing loss in otological disorders
: a decade-long epidemiological study in a South
Indian populationvia ScienceDirect Publication: Brazilian Journal of
OtorhinolaryngologyPublication date: Available online 13 February 2016
*Source:*Brazilian Journal of OtorhinolaryngologyAuthor(s): Santoshi Kumari
Manche, Jangala Madhavi, Koralla Raja Meganadh, Akka JyothyIntroductionTinnitus
is a common disorder that occurs frequently across all strata of population and
has an important health concern. Tinnitus is often associated with different
forms of hearing loss of varying severity.ObjectiveThe present study aimed to
identify ...περισσότερα »
The Sinus and Nasal Quality of Life Survey (SN-5)
Cross-cultural adaptation and validation of the
Sinus and Nasal Quality of Life Survey (SN-5) into Brazilian Portuguesevia
ScienceDirect Publication: Brazilian Journal of Otorhinolaryngology
*Source:*Brazilian Journal of OtorhinolaryngologyAuthor(s): Priscila Regina
Candido Espinola Uchoa, Thiago Freire Pinto Bezerra, Élcio Duarte Lima, Marco
Aurélio Fornazieri, Fabio de Rezende Pinna, Fabiana de Araújo Sperandio, Richard
Louis VoegelsIntroductionThe concept of quality of life is subjective and
variable definition, which depends on the individual's perception of their state
of heal...περισσότερα »
Chorda tympani schwannoma
*: one new case revealed during malignant
otitis externa and review of the literature**via ScienceDirect Publication:
Brazilian Journal of Otorhinolaryngology*Introduction*Facial nerve schwannomas
(FNS) are a rare entity that are poorly reported in literature. Although the
estimated prevalence is extremely low, FNS are the most common primary tumor of
the facial nerve. FNS occur throughout the course of the facial nerve and its
branches, and chorda tympani schwannomas are quite rare. In 2010, Huoh and
Cheung reported that seven additional chorda tympani schwannoma had appeared in
l...περισσότερα »
Prevention of neck infection by endoscopic suture closure of pyriform sinus fistulae
*: a report of two cases**via ScienceDirect
Publication: Brazilian Journal of Otorhinolaryngology*Introduction*Pyriform
sinus fistula (PSF) is a rare congenital disease that causes neck abscess and/or
suppurative thyroiditis.1 Complete excision of the fistula is the most common
treatment.2However, in the last decade, endoscopic cauterization of the opening
of the fistula has been reported as a minimally invasive surgery for PSF.3 and 4
Although some studies have suggested that the latter option is reliable and
minimally invasive, it requires repetitive procedures in some cases.4
Mo...περισσότερα »
Mometasone furoate in the treatment of mild, moderate, or severe persistent allergic rhinitis
: a non-inferiority study (PUMA)via ScienceDirect
Publication: Brazilian Journal of Otorhinolaryngology*Source:*Brazilian Journal
of OtorhinolaryngologyAuthor(s): Martti Anton Antila, Fabio Morato Castro,
Flavio Sano, Adelmir Machado, Fatima Fernandes, Nelson Augusto Rosário Filho,
Rafael StelmachIntroductionAllergic rhinitis is considered the most prevalent
respiratory disease in Brazil and worldwide, with great impact on quality of
life, affecting social life, sleep, and also performance at school and at
work.ObjectiveTo compare the efficacy and safety of two formulations
contai...περισσότερα »
Feeding methods for children with cleft lip and/or palate
: a systematic reviewvia ScienceDirect Publication:
Brazilian Journal of OtorhinolaryngologyPublication date: Available online 2
March 2016*Source:*Brazilian Journal of OtorhinolaryngologyAuthor(s): Giesse
Albeche Duarte, Ramon Bossardi Ramos, Maria Cristina de Almeida Freitas Cardoso
IntroductionFeeding difficulties in children with cleft lip and palate (CLP) are
frequent and appear at birth due to impairment of sucking and swallowing
functions. The use of appropriate feeding methods for the different types of
cleft and the period of the child's life is of utmost importance for
th...περισσότερα »
Adult tonsillectomy
: postoperative pain depends on indicationsvia
ScienceDirect Publication: Brazilian Journal of Otorhinolaryngology
*Source:*Brazilian Journal of OtorhinolaryngologyAuthor(s): Olaf Zagólski,
Mariusz Gajda, Paweł Stręk, Michael John Kozlowski, Artur Gądek, Jerzy Nyzio
IntroductionIntense pain is one of the most important postoperative complaints
after tonsillectomy. It is often described by patients as comparable to the pain
that accompanies an acute tonsillitis. Although recurrent tonsillitis is the
most frequent indication for surgery, many tonsillectomies are performed due to
other...περισσότερα »
Genomic profile of a squamous cell carcinoma ex pleomorphic adenoma compared to a head and neck squamous cell carcinoma
*Case report*Genomic profile of a squamous
cell carcinoma ex pleomorphic adenoma compared to a head and neck squamous cell
carcinoma ☆*Perfil genômico de um carcinoma espinocelular ex-adenoma pleomórfico
comparado a um carcinoma espinocelular de cabeça e pescoço ☆* *- Fernanda
Viviane Marianoa, , , - Luis Fernando Vidal Saccomania, - Karina Giovanettia,
- André Del Negrob, - Luiz Paulo Kowalskic, - Ana Cristina Victorino
Krepischid, - Albina Altemania* - *a Pathology Department, Faculdade de
Ciências Médicas, Universidade Estadual de Campinas (UNICAMP), Campinas,
SP...περισσότερα »
Carcinoma ex-pleomorphic adenoma derived from recurrent pleomorphic adenoma
shows important difference by array CGH compared
to recurrent pleomorphic adenoma without malignant transformationvia
ScienceDirect Publication: Brazilian Journal of OtorhinolaryngologyPublication
date: Available online 24 February 2016*Source:*Brazilian Journal of
OtorhinolaryngologyAuthor(s): Fernanda Viviane Mariano, Karina Giovanetti, Luis
Fernando Vidal Saccomani, André Del Negro, Luiz Paulo Kowalski, Ana Cristina
Victorino Krepischi, Albina AltemaniIntroductionA key step of cancer development
is the progressive accumulation of genomic changes resulting in disruption of
sever...περισσότερα »
Senile hearing loss and vestibular activity
The relationship between via ScienceDirect
Publication: Brazilian Journal of OtorhinolaryngologyPublication date: Available
online 28 February 2016*Source:*Brazilian Journal of Otorhinolaryngology
Author(s): Hanifi Kurtaran, Baran Acar, Emre Ocak, Emre MiriciIntroductionA
considerable high number of SNHL patients also suffer from dizziness and related
vestibular symptoms.ObjectiveTo evaluate the association of vestibular
dysfunction and sensorineural hearing loss (SNHL) in adult
patients.MethodsProspective, double-blinded, controlled studies composed by 63
adult patients without any...περισσότερα »
Enhanced recovery after surgery (ERAS) for head and neck oncology patients
Enhanced recovery after surgery (ERAS) for head and
neck oncology patients: Abstract:To describe the development of an enhanced
recovery after surgery (ERAS) protocol for people undergoing surgery for head
and neck cancer.Document Type: Research ArticleDOI:
http://dx.doi.org/10.1111/coa.12482
Endoscopic polypectomy in the clinic: a pilot cost‐effectiveness analysis
Endoscopic polypectomy in the clinic: a pilot
cost‐effectiveness analysis: Abstract:The purpose of this *pilot* economic
evaluation was to assess the cost‐effectiveness of the endoscopic polypectomy in
the clinic (EPIC) procedure compared to formal endoscopic sinus surgery (ESS)
for the treatment of select chronic rhinosinusitis (CRS) patients with nasal
polyposis.Document Type: Research ArticleDOI:
http://dx.doi.org/10.1111/coa.12473
Salivary Duct Carcinoma
A 20-Year Review of 75 Cases of Salivary Duct
Carcinoma.:JAMA Otolaryngol Head Neck Surg. 2016 Mar 3;Authors: Gilbert MR,
Sharma A, Schmitt NC, Johnson JT, Ferris RL, Duvvuri U, Kim SAbstractImportance:
Salivary duct carcinoma is a rare, aggressive malignancy of the salivary glands.
Owing to its rare nature, clinical data are limited, and only a few clinical
studies comprise more than 50 patients.Objective: To review the University of
Pittsburgh Medical Center's experience with salivary duct carcinoma over a
20-year period, focusing on demographics, presentation, treatment, a...περισσότερα »
Usefulness of Upper Airway Endoscopy in the Evaluation of Pediatric Pulmonary Aspiration.
Usefulness of Upper Airway Endoscopy in the
Evaluation of Pediatric Pulmonary Aspiration.JAMA Otolaryngol Head Neck Surg.
2016 Mar 3;Authors: Adil E, Gergin O, Kawai K, Rahbar R, Watters KAbstract
Importance: There is no consensus on the evaluation of pediatric patients with
aspiration.Objectives: To determine the yield of direct laryngoscopy and
bronchoscopy (DLB) using general anesthesia in pediatric patients who aspirate
and to identify clinical predictors of aspiration-related airway lesions.Design,
Setting, and Participants: Retrospective review at a tertiary referral
c...περισσότερα »
Does early communication mediate the relationship between motor ability and social function in children with cerebral palsy?
Publication date: June–July 2016*Source:*Research
in Developmental Disabilities, Volumes 53–54Author(s): Belinda Lipscombe, Roslyn
N. Boyd, Andrea Colemen, Michael Fahey, Barry Rawicki, Koa Whittingham
BackgroundChildren diagnosed with neurodevelopmental conditions such as cerebral
palsy (CP) are at risk of experiencing restrictions in social activities
negatively impacting their subsequent social functioning. Research has
identified motor and communication ability as being unique determinants of
social function capabilities in children with CP, to date, no research has
investigat...περισσότερα »
Part C early intervention utilization in preterm infants: Opportunity for referral from a NICU follow-up clinic
Publication date: June–July 2016*Source:*Research
in Developmental Disabilities, Volumes 53–54Author(s): Michelle Greene, Kousiki
PatraObjectiveEarly Intervention (EI) services promote development for preterm
infants. In the state of Illinois, Child and Family Connections (CFC) is the
intake agency that determines qualification for EI services. In Illinois, all
extremely low birth weight (ELBW) infants are eligible for and referred to CFC
at discharge from the Neonatal Intensive Care Unit (NICU). This study
investigated: (1) patterns of CFC and EI enrollment, and; (2) predictors
...περισσότερα »
Association of Caffeine and Hearing Recovery
Association of Caffeine and Hearing Recovery After
Acoustic Overstimulation Events in a Guinea Pig ModelJAMA Otolaryngol Head Neck
Surg. 2016 Mar 3;Authors: Zawawi F, Bezdjian A, Mujica-Mota M, Rappaport J,
Daniel SJAbstractImportance: Noise-induced hearing loss is an increasingly
worrisome problem. Although caffeine intake is common in people involved in
noise-related environments, the effect of caffeine on the recovery of hearing
after a temporary threshold shift requires further understanding.Objectives: To
determine whether caffeine impairs hearing recovery in a guinea pi...περισσότερα »
Late onset and high-frequency dominant hearing loss in a family with MYH9 disorder
Late onset and high-frequency dominant hearing loss
in a family with MYH9 disorder: Abstract*MYH9* disorder is a rare
autosomal-dominant disorder. We previously reported that it is caused by
mutations in the gene for nonmuscle myosin heavy chain IIA (NMMHC-IIA). *MYH9*
disorder causes congenital macrothrombocytopenia accompanied by progressive
sensorineural hearing loss, nephropathy, and cataract. However, there are few
reports that describe the audiological features of *MYH9* disorder. The
objective of this study was to characterize auditory and other phenotypes of
patients with ...περισσότερα »
Haemophilus influenzae biofilm formation in chronic otitis media with effusion
Haemophilus influenzae biofilm formation in chronic
otitis media with effusion: AbstractOtitis media with effusion (OME) is a highly
prevalent disease in children, but the exact pathogenesis and role of bacteria
are still not well understood. This study aimed to investigate the presence of
otopathogenic bacteria in the middle ear effusion (MEE) and adenoid of children
with chronic OME (COME), and to investigate in vivo whether these bacteria,
especially *Haemophilus influenzae*, are organized as a biofilm in the middle
ear fluid. MEE and adenoid samples were collected from 21 pati...περισσότερα »
Halitosis associated volatile sulphur compound levels in patients with laryngopharyngeal reflux
Halitosis associated volatile sulphur compound
levels in patients with laryngopharyngeal reflux: AbstractPrevious reports have
suggested that laryngopharyngeal reflux (LPR) may cause halitosis. However, it
remains unclear if LPR is a risk factor for halitosis. The aim of this study was
to investigate if patients diagnosed with LPR have an increased probability of
halitosis compared to a normal population. Fifty-eight patients complaining of
LPR symptoms and 35 healthy subjects were included in the study. A LPR diagnosis
was made using an ambulatory 24-h double pH-probe monitor, whi...περισσότερα »
Post-laryngectomy voice rehabilitation with a voice prosthesis
in a young girl with advanced thyroid cancervia
Auris Nasus LarynxPublication date: Available online 5 March 2016*Source:*Auris
Nasus LarynxAuthor(s): Takahiro Fukuhara, Masayuki Miyoshi, Taihei Fujii,
Naritomo Miyake, Kenkichiro Taira, Satoshi Koyama, Daizo Taguchi, Kazunori
Fujiwara, Hideyuki Kataoka, Hiroya Kitano, Hiromi TakeuchiThe aim of this report
is to evaluate the effects of voice rehabilitation with a voice prosthesis in a
young patient with thyroid cancer. A 17-year-old girl underwent voice
restoration with a voice prosthesis after laryngectomy to treat thyroid
cancer...περισσότερα »
Cervicofacial non-tuberculous mycobacteria
: A report of 30 casesvia European Annals of
Otorhinolaryngology, Head and Neck DiseasesPublication date: Available online 4
March 2016*Source:*European Annals of Otorhinolaryngology, Head and Neck
DiseasesAuthor(s): P. Rives, M. Joubert, E. Launay, A. Guillouzouic, F.
Espitalier, O. MalardBackgroundMycobacterial infection is the most common cause
of cervical granuloma, implicating either a tuberculous or a non-tuberculous
mycobacterium (NTM). NTM is a ubiquitous organism, found in soil, water, food,
etc. The most frequently implicated is Mycobacterium avium-intracellular. Most
au...περισσότερα »
Neuromuscular blockade in patients receiving tracheostomies
Outcomes following via International Journal of
Pediatric OtorhinolaryngologyPublication date: Available online 4 March 2016
*Source:*International Journal of Pediatric OtorhinolaryngologyAuthor(s): Eric
Bauer, Justin B. Mahida, Laura A. Boomer, Jeffrey E. Lutmer, Peter C. Minneci,
Katherine J. Deans, Charles A. ElmaraghyObjectiveThe purpose of this study is to
determine whether the use of neuromuscular blockade agents (NMBAs) in pediatric
patients following tracheostomy is associated with increased rates of
complications or a prolonged length of stay.MethodsThis was a
single-center...περισσότερα »
Corrigendum to “Characterization of MCAM contribution to neuroinflammation using a new murine knockout model” J. Neuroimmunol., 275 (1–2) (2014) 143
medicinesfakianakisστοMedicine by
Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel
:00302841026182 & 00306932607174Πριν από 28 δευτερόλεπτα
The authors regret the mistake made by the
12th International Congress of Neuroimmunology when publishing the conference
abstract booklet. The correct authorship of this abstract should have been:
‘Marc Charabati, Catherine Larochelle, Lyne Bourbonnière, Simone Terouz, Sandra
Larouche, Marc-Andér Lecuyer, Jorge Ivan Alvarez & Alexandre Prat’. At
the time of publication of this abstract, all […]
Corrigendum to “Characterization of MCAM contribution to neuroinflammation using a new murine knockout model” J. Neuroimmunol., 275 (1–2) (2014) 143
medicinesfakianakisστοMedicine by
Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel
:00302841026182 & 00306932607174Πριν από 28 δευτερόλεπτα
The authors regret the mistake made by the
12th International Congress of Neuroimmunology when publishing the conference
abstract booklet. The correct authorship of this abstract should have been:
‘Marc Charabati, Catherine Larochelle, Lyne Bourbonnière, Simone Terouz, Sandra
Larouche, Marc-Andér Lecuyer, Jorge Ivan Alvarez & Alexandre Prat’. At
the time of publication of this abstract, all […]
Activation of the adenosine A receptor exacerbates experimental autoimmune neuritis in Lewis rats in association with enhanced humoral immunity
medicinesfakianakisστοMedicine by
Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel
:00302841026182 & 00306932607174Πριν από 28 δευτερόλεπτα
Accumulated evidence demonstrated that
Adenosine A2A receptor (A2AR) is involved in the inflammatory diseases. In
present study, we showed that a selective A2AR agonist, CGS21680, exacerbated
experimental autoimmune neuritis in Lewis rats induced with bovine peripheral
myelin. The exacerbation was accompanied with reduced CD4+Foxp3+ T cells,
increased CD4+CXCR5+ T cells, B cells, dendritic cells and […]
Activation of the adenosine A receptor exacerbates experimental autoimmune neuritis in Lewis rats in association with enhanced humoral immunity
medicinesfakianakisστοMedicine by
Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel
:00302841026182 & 00306932607174Πριν από 28 δευτερόλεπτα
Accumulated evidence demonstrated that
Adenosine A2A receptor (A2AR) is involved in the inflammatory diseases. In
present study, we showed that a selective A2AR agonist, CGS21680, exacerbated
experimental autoimmune neuritis in Lewis rats induced with bovine peripheral
myelin. The exacerbation was accompanied with reduced CD4+Foxp3+ T cells,
increased CD4+CXCR5+ T cells, B cells, dendritic cells and […]
Corrigendum to “Expression of DNA methylation genes in secondary progressive multiple sclerosis” J. Neuroimmunol. 290 (2016 Jan. 15) 66–9
medicinesfakianakisστοMedicine by
Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel
:00302841026182 & 00306932607174Πριν από 28 δευτερόλεπτα
The authors regret . (Source: Journal of
Neuroimmunology) from #Medicine-SfakianakisAlexandros via o.lakala70 on
Inoreader http://ift.tt/1QCzaWA via IFTTT
Corrigendum to “Expression of DNA methylation genes in secondary progressive multiple sclerosis” J. Neuroimmunol. 290 (2016 Jan. 15) 66–9
medicinesfakianakisστοMedicine by
Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel
:00302841026182 & 00306932607174Πριν από 28 δευτερόλεπτα
The authors regret . (Source: Journal of
Neuroimmunology) from #Medicine-SfakianakisAlexandros via o.lakala70 on
Inoreader http://ift.tt/1QCzaWA via IFTTT Medicine by Alexandros
G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182
& 00306932607174
Splenectomy following MCAO inhibits the TLR4–NF-κB signaling pathway and protects the brain from neurodegeneration in rats
medicinesfakianakisστοMedicine by
Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel
:00302841026182 & 00306932607174Πριν από 28 δευτερόλεπτα
The Toll-like receptor 4(TLR4)/nuclear
factor kappa B NF-κB inflammatory pathway contributes to secondary inflammation
in many diseases including stroke. Moreover, the neuroprotective effect of
splenectomy in stroke is supported by a vast body of experimental evidence.
Nevertheless, the underlying mechanism(s) by which splenectomy enhance
neuroprotection in stroke is still poorly understood. Our study aimed to
[…]
Splenectomy following MCAO inhibits the TLR4–NF-κB signaling pathway and protects the brain from neurodegeneration in rats
medicinesfakianakisστοMedicine by
Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel
:00302841026182 & 00306932607174Πριν από 28 δευτερόλεπτα
The Toll-like receptor 4(TLR4)/nuclear
factor kappa B NF-κB inflammatory pathway contributes to secondary inflammation
in many diseases including stroke. Moreover, the neuroprotective effect of
splenectomy in stroke is supported by a vast body of experimental evidence.
Nevertheless, the underlying mechanism(s) by which splenectomy enhance
neuroprotection in stroke is still poorly understood. Our study aimed to
[…]
Decreased serum IL-27 and IL-35 levels are associated with disease severity in neuromyelitis optica spectrum disorders
medicinesfakianakisστοMedicine by
Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel
:00302841026182 & 00306932607174Πριν από 28 δευτερόλεπτα
The interleukin 12 (IL-12) family plays
important roles in autoimmune diseases. To explore the roles of the IL-12 family
members IL-27 and IL-35 in the pathogenesis of neuromyelitis optica spectrum
disorders (NMOSD), we determined their serum and cerebral spinal fluid levels
and assessed potential correlations with clinical characteristics. Serum IL-27
levels were negatively correlated with […]
Decreased serum IL-27 and IL-35 levels are associated with disease severity in neuromyelitis optica spectrum disorders
medicinesfakianakisστοMedicine by
Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel
:00302841026182 & 00306932607174Πριν από 28 δευτερόλεπτα
The interleukin 12 (IL-12) family plays
important roles in autoimmune diseases. To explore the roles of the IL-12 family
members IL-27 and IL-35 in the pathogenesis of neuromyelitis optica spectrum
disorders (NMOSD), we determined their serum and cerebral spinal fluid levels
and assessed potential correlations with clinical characteristics. Serum IL-27
levels were negatively correlated with […]
Recreational Vehicle Related Forceful Head Impact
Outcomes in Pediatric Patients with via
International Journal of Pediatric OtorhinolaryngologyPublication date:
Available online 4 March 2016*Source:*International Journal of Pediatric
OtorhinolaryngologyAuthor(s): Cameron C Sheehan, Meredith Lind, Justin B Mahida,
Garth Essig, Charles A ElmaraghyPurposeTo compare outcomes in pediatric patients
suffering forceful head impact during recreational vehicle use to patients with
forceful head impact from other mechanisms.MethodsRetrospective cohort study of
all patients 3-18 years old who suffered forceful head impact (any traumatic
mec...περισσότερα »
Children after open airway surgery for laryngotracheal stenosis
Long-term quality of life in via International
Journal of Pediatric OtorhinolaryngologyPublication date: Available online 4
March 2016*Source:*International Journal of Pediatric Otorhinolaryngology
Author(s): B. Pullens, K. Dulfer, C.M.P. Buysse, L.J. Hoeve, M.K. Timmerman,
K.F.M. JoostenObjectivesThe purpose of this study is to evaluate the long-term
health related quality of life (HRQoL) in a cohort of children surgically
treated for laryngotracheal stenosis (LTS).Study designProspective cohort
study.MethodsParents of children between 4 and 18 years at follow-up completed
the Chi...περισσότερα »
Bipolar tonsillotomy
: A novel and effective tonsillotomy techniquevia
International Journal of Pediatric OtorhinolaryngologyPublication date: May 2016
*Source:*International Journal of Pediatric Otorhinolaryngology, Volume 84
Author(s): Chanan Shaul, Pierre D. Attal, Yehuda Schwarz, Nidal Muhanna, Dvora
Izgelov, Uri Peleg, Jean-Yves SichelObjectiveTo present, for the first time,
tonsil size reduction using reusable bipolar forceps electrocautery (RBFE), as a
treatment for pediatric OSAS and to assess the safety and efficacy of the
procedure.MethodsA prospective interventional design study was
performed....περισσότερα »
Associations between otitis media and child behavioural and learning difficulties
: Results from a Danish cohortvia International
Journal of Pediatric OtorhinolaryngologyPublication date: May 2016
*Source:*International Journal of Pediatric Otorhinolaryngology, Volume 84
Author(s): J. Niclasen, C. Obel, P. Homøe, A. Kørvel-Hanquist, J. Dammeyer
ObjectivesFindings from studies investigating early childhood episodes of otitis
media (OM) and developmental outcomes are inconclusive. This may in part be
because large-scale prospective studies controlling for relevant confounding
factors are sparse. The present study investigates associations between OM in
early childhoo...περισσότερα »
Otitis media with effusion in an allergic animal model
: A functional and morphological studyvia
International Journal of Pediatric OtorhinolaryngologyPublication date: May 2016
*Source:*International Journal of Pediatric Otorhinolaryngology, Volume 84
Author(s): Dong-Kee Kim, Hyu Eun Park, Sang-A. Back, Hyang Rim Park, Soo Whan
Kim, Yooyeon Park, Sang Won Yeo, Shi-Nae ParkObjectivesAllergy is considered as
one of important etiologic factor of otitis media with effusion (OME). In
present study, we evaluated the causal effect of allergy on OME in an animal
model, and investigated the secondary effect of bacterial
infection.MethodsAllergy ...περισσότερα »
Although there is evidence that SEs have a potential role in the pathogenesis of chronic inflammatory diseases, there is no evidence that the inflammation process is initiated by SEs in patients with OME.
Do Staphylococcus aureus superantigens play a role
in the pathogenesis of otitis media with effusion in children?via International
Journal of Pediatric OtorhinolaryngologyPublication date: Available online 4
March 2016*Source:*International Journal of Pediatric Otorhinolaryngology
Author(s): Deniz Demir, Oğuz Karabay, Mehmet Güven, Gürkan Kayabasoğlu, Mahmut
Sinan YılmazObjectivesStaphylococcal enterotoxins (SEs), acting as
superantigens, have been reported to be involved in the pathogenesis of chronic
inflammatory diseases of the upper and lower airway. There has been no previous
s...περισσότερα »
Ethische Aspekte der ästhetischen Medizin und Chirurgie
Ethische Aspekte der ästhetischen Medizin und
Chirurgie: ZusammenfassungDie medizinische Ethik definiert die Prinzipien
„respect of autonomy“, „non-maleficence“, „benefience“ und „justice“. In der
ästhetischen Medizin und Chirurgie erweitert der Begriff der ästhetischen
Indikation das Spektrum ärztlichen Handelns. Dabei gelten die genannten
Prinzipien gleichermaßen. Es geht um eine nichtmedizinische Indikation für
medizinische, aber nicht auf Heilbehandlung bezogene Maßnahmen. Eine Indikation
liegt vor, wenn eine ärztliche Maßnahme unter Abwägung ihres potenziellen
Nutzens und Scha...περισσότερα »
Delegation ärztlicher Leistungen
Delegation ärztlicher Leistungen:
ZusammenfassungDie Delegation ärztlicher Leistungen an nichtärztliche
Mitarbeiter gewinnt immer mehr an Bedeutung. Angesichts der demografischen
Entwicklung stehen künftig weniger Ärzte in der Versorgung zur Verfügung,
während die Nachfrage nach ärztlicher Versorgung stetig steigt. Die rechtliche
Zulässigkeit der Delegation richtet sich nach dem Grundsatz der persönlichen
Leistungserbringung, wonach ärztliche Leistungen grundsätzlich persönlich zu
erbringen sind. Gemäß § 2 der Anlage 24 zum BMV-Ä darf der Arzt Leistungen, die
er aufgrund der erford...περισσότερα »
Post-laryngectomy voice rehabilitation with a voice prosthesis in a young girl with advanced thyroid cancer
Post-laryngectomy voice rehabilitation with a voice
prosthesis in a young girl with advanced thyroid cancer: The aim of this report
is to evaluate the effects of voice rehabilitation with a voice prosthesis in a
young patient with thyroid cancer. A 17-year-old girl underwent voice
restoration with a voice prosthesis after laryngectomy to treat thyroid cancer.
She completed voice-related questionnaires (the Voice Handicap Index-10 and
Voice-Related Quality Of Life Survey) at ages 17 and 21 and underwent phonetic
functional evaluation. The sound spectrograms of her phonation using
the...περισσότερα »
Senegenin Ameliorate Acute Lung Injury Through Reduction of Oxidative Stress and Inhibition of Inflammation in Cecal Ligation and Puncture-Induced Sepsis Rats
medicinesfakianakisστοMedicine by
Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel
:00302841026182 & 00306932607174Πριν από 59 δευτερόλεπτα
Abstract The purpose of this study was to
assess the protective effect of senegenin on acute lung injury (ALI) in rats
induced by sepsis. Rat ALI model was reproduced by cecal ligation and puncture
(CLP). All rats were randomly divided into five groups: group 1 (control), group
2 (CLP), group 3 (CLP + senegenin 15 mg/kg), group […]
Senegenin Ameliorate Acute Lung Injury Through Reduction of Oxidative Stress and Inhibition of Inflammation in Cecal Ligation and Puncture-Induced Sepsis Rats
medicinesfakianakisστοMedicine by
Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel
:00302841026182 & 00306932607174Πριν από 59 δευτερόλεπτα
Abstract The purpose of this study was to
assess the protective effect of senegenin on acute lung injury (ALI) in rats
induced by sepsis. Rat ALI model was reproduced by cecal ligation and puncture
(CLP). All rats were randomly divided into five groups: group 1 (control), group
2 (CLP), group 3 (CLP + senegenin 15 mg/kg), group […]
Aberrant excitatory rewiring of layer V pyramidal neurons early after neocortical trauma
medicinesfakianakisστοMedicine by
Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel
:00302841026182 & 00306932607174Πριν από 59 δευτερόλεπτα
Publication date: Available online 5 March
2016 Source:Neurobiology of Disease Author(s): D. Koji Takahashi, Feng Gu,
Isabel Parada, Shri Vyas, David A. Prince Lesioned neuronal circuits form new
functional connections after a traumatic brain injury (TBI). In humans and
animal models, aberrant excitatory connections that form after TBI may
contribute to the pathogenesis of post-traumatic […]
Editorial Board
medicinesfakianakisστοMedicine by
Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel
:00302841026182 & 00306932607174Πριν από 59 δευτερόλεπτα
Publication date: May 2016
Source:Neurobiology of Disease, Volume 89 from #Medicine-SfakianakisAlexandros
via o.lakala70 on Inoreader http://ift.tt/1Qzmkf5 via IFTTT
Aberrant excitatory rewiring of layer V pyramidal neurons early after neocortical trauma
medicinesfakianakisστοMedicine by
Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel
:00302841026182 & 00306932607174Πριν από 59 δευτερόλεπτα
Publication date: Available online 5 March
2016 Source:Neurobiology of Disease Author(s): D. Koji Takahashi, Feng Gu,
Isabel Parada, Shri Vyas, David A. Prince Lesioned neuronal circuits form new
functional connections after a traumatic brain injury (TBI). In humans and
animal models, aberrant excitatory connections that form after TBI may
contribute to the pathogenesis of post-traumatic […]
Editorial Board
medicinesfakianakisστοMedicine by
Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel
:00302841026182 & 00306932607174Πριν από 59 δευτερόλεπτα
Publication date: May 2016
Source:Neurobiology of Disease, Volume 89 from #Medicine-SfakianakisAlexandros
via o.lakala70 on Inoreader http://ift.tt/1Qzmkf5 via IFTTT Medicine by
Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel
:00302841026182 & 00306932607174
Prognostic factors after resection of colorectal liver metastases following preoperative second-line chemotherapy: Impact of RAS mutations
medicinesfakianakisστοMedicine by
Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel
:00302841026182 & 00306932607174Πριν από 59 δευτερόλεπτα
Publication date: Available online 5 March
2016 Source:European Journal of Surgical Oncology (EJSO) Author(s): Guillaume
Passot, Yun S. Chun, Scott E. Kopetz, Michael J. Overman, Claudius Conrad,
Thomas A. Aloia, Jean-Nicolas Vauthey BackgroundAfter resection of colorectal
liver metastases (CLM), RAS mutations are associated with modest survival
benefit and second-line chemotherapy confers limited hope for cure.ObjectiveTo
[…]
Prognostic factors after resection of colorectal liver metastases following preoperative second-line chemotherapy: Impact of RAS mutations
medicinesfakianakisστοMedicine by
Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel
:00302841026182 & 00306932607174Πριν από 59 δευτερόλεπτα
Publication date: Available online 5 March
2016 Source:European Journal of Surgical Oncology (EJSO) Author(s): Guillaume
Passot, Yun S. Chun, Scott E. Kopetz, Michael J. Overman, Claudius Conrad,
Thomas A. Aloia, Jean-Nicolas Vauthey BackgroundAfter resection of colorectal
liver metastases (CLM), RAS mutations are associated with modest survival
benefit and second-line chemotherapy confers limited hope for cure.ObjectiveTo
[…]
Reviving virus based cancer vaccines by using cytomegalovirus vectors expressing modified tumor antigens.
*Reviving virus based cancer vaccines by using
cytomegalovirus vectors expressing modified tumor antigens.*Oncoimmunology.
2016;5(1):e1056974Authors: Qiu Z, Grenier JM, Khanna KMAbstractCancer vaccines
that have utilized various immunization strategies to induce antitumor immunity
have largely failed in clinical settings. We have recently developed a cancer
vaccine using a cytomegalovirus (CMV) based vector that expressed a modified
melanoma antigen that elicited a robust antitumor CD8(+) T cell response and
tumor rejection.PMID: 26942064 [PubMed - as supplied by publisher]...περισσότερα »
Density of tumor-infiltrating lymphocytes correlates with extent of brain edema and overall survival time in patients with brain metastases.
*Density of tumor-infiltrating lymphocytes
correlates with extent of brain edema and overall survival time in patients with
brain metastases.*Oncoimmunology. 2016;5(1):e1057388Authors: Berghoff AS, Fuchs
E, Ricken G, Mlecnik B, Bindea G, Spanberger T, Hackl M, Widhalm G, Dieckmann K,
Prayer D, Bilocq A, Heinzl H, Zielinski C, Bartsch R, Birner P, Galon J,
Preusser MAbstractThe immune microenvironment of the brain differs from that of
other organs and the role of tumor-infiltrating lymphocytes (TILs) in brain
metastases (BM), one of the most common and devastating complication
...περισσότερα »
Favorable overall survival in stage III melanoma patients after adjuvant dendritic cell vaccination.
*Favorable overall survival in stage III melanoma
patients after adjuvant dendritic cell vaccination.*Oncoimmunology.
2016;5(1):e1057673Authors: Bol KF, Aarntzen EH, Hout FE, Schreibelt G, Creemers
JH, Lesterhuis WJ, Gerritsen WR, Grunhagen DJ, Verhoef C, Punt CJ, Bonenkamp JJ,
de Wilt JH, Figdor CG, de Vries IJAbstractMelanoma patients with regional
metastatic disease are at high risk for recurrence and metastatic disease,
despite radical lymph node dissection (RLND). We investigated the immunologic
response and clinical outcome to adjuvant dendritic cell (DC) vaccination
in...περισσότερα »
Long-lasting multifunctional CD8(+) T cell responses in end-stage melanoma patients can be induced by dendritic cell vaccination.
*Long-lasting multifunctional CD8(+) T cell
responses in end-stage melanoma patients can be induced by dendritic cell
vaccination.*Oncoimmunology. 2016;5(1):e1067745Authors: Wimmers F, Aarntzen EH,
Duiveman-deBoer T, Figdor CG, Jacobs JF, Tel J, de Vries IJAbstractCytotoxic T
cells are considered crucial for antitumor immunity and their induction is the
aim of various immunotherapeutic strategies. High frequencies of tumor-specific
CD8(+) T cells alone, however, are no guarantee for long-term tumor control.
Here, we analyzed the functionality of tumor-specific CD8(+) T cells
...περισσότερα »
Targeting TNF alpha as a novel strategy to enhance CD8(+) T cell-dependent immune response in melanoma?
*Targeting TNF alpha as a novel strategy to enhance
CD8(+) T cell-dependent immune response in melanoma?*Oncoimmunology.
2016;5(1):e1068495Authors: Bertrand F, Rochotte J, Colacios C, Montfort A,
Andrieu-Abadie N, Levade T, Benoist H, Ségui BAbstractTumor Necrosis Factor α
(TNF) is a pleiotropic cytokine exhibiting a dual activity in oncoimmunology,
either acting as a cytotoxic effector produced by leukocytes or behaving as an
immunosuppressive molecule. We have just discovered that TNF signaling impairs
the accumulation of tumor-infiltrating CD8(+) T lymphocytes in
experimen...περισσότερα »
The extent to which melanoma alters tissue-resident dendritic cell function correlates with tumorigenicity.
*The extent to which melanoma alters
tissue-resident dendritic cell function correlates with tumorigenicity.*
Oncoimmunology. 2016;5(1):e1069462Authors: Hargadon KMAbstractWe have shown that
melanoma-derived factors alter the function of differentiated tissue-resident
dendritic cells (DC) in a tumorigenicity-dependent manner. Soluble factors,
including TGFβ1 and VEGF-A, contributed to dendritic cell dysfunction associated
with a highly-aggressive melanoma and conferred a phenotype upon DC likely to
favor immune escape and tumor outgrowth.PMID: 26942090 [PubMed - as supplied
...περισσότερα »
PD-1 expression conditions T cell avidity within an antigen-specific repertoire.
*PD-1 expression conditions T cell avidity within
an antigen-specific repertoire.*Oncoimmunology. 2016;5(1):e1104448Authors: Simon
S, Vignard V, Florenceau L, Dreno B, Khammari A, Lang F, Labarriere NAbstract
Despite its negative regulatory role on tumor-specific T cells, Programmed cell
death 1 (PD-1) is also a marker of activated tumor-infiltrating T cells. In
cancer, PD-1 blockade partially reverses T cell dysfunction allowing the
amplification of tumor reactive T cells. Here, we investigated the role of PD-1
signaling on effector/memory human T cells specific for shared m...περισσότερα »
Doubling the blockade for melanoma immunotherapy.
*Doubling the blockade for melanoma immunotherapy.*
Oncoimmunology. 2016;5(1):e1106127Authors: Galluzzi L, Eggermont A, Kroemer G
PMID: 26942094 [PubMed - as supplied by publisher]from melanoma2 via als.fakia
on Inoreader http://ift.tt/21PZqnzvia IFTTT
First oncolytic virus approved for melanoma immunotherapy.
*First oncolytic virus approved for melanoma
immunotherapy.*Oncoimmunology. 2016;5(1):e1115641Authors: Pol J, Kroemer G,
Galluzzi LAbstractOn 2015, October 27th, the US Food and Drug Administration
(FDA) has officially approved talimogene laherparepvec (T-VEC, also known as
OncoVEX(GM-CSF)) for use in melanoma patients with injectable but non-resectable
lesions in the skin and lymph nodes. T-VEC (which is commercialized by Amgen,
Inc. under the name of Imlygic®) becomes therefore the first oncolytic virus
approved for cancer therapy in the US.PMID: 26942095 [PubMed - as
supp...περισσότερα »
Fwd: Pharmaceutical Biotechnology, Year 2015, Issue 06 -New Issue Alert.
From: order@email.oriprobe.comDate: March 06, 2016
at 08:07AM[image: 1PHav7d]New Issue TOC Alert*Dear Valued Customer*, [image:
1SchPFA] We are pleased to deliver your requested table of contents alert for
*Pharmaceutical Biotechnology*. Year *2015* Issue *06* is now available on CAOD.
*In this issue:*Mechanism Study on the Anti-melanoma Effects of Vaccines against
Ectopic Human Chorionic Gonadotrophin Beta(eβhCG)
(抗βhCG多表位融合蛋白疫苗治疗实验小鼠黑色素瘤的机制研究)YANG Jie, LIU Zu-hui, CHENG Qian, LI Man-man,
YUAN Yu-ting, MIAO Zi-tao, LI Hui-zhong, JIN Liang, CAO Rong-yue, Jiangsu Key
Labor...περισσότερα »
The Effects of an Educational Intervention on Preventing Cervical Cancer Among Vietnamese Women in Southern Taiwan
Abstract This paper aims to conduct and evaluate an
educational intervention on preventing cervical cancer among married immigrant
women of Vietnamese origin. The study design was a quasi-experimental method
with two groups. In total, 260 married immigrant women of Vietnamese origin with
national health insurance at least 30 years of age were recruited from November
2013 to January 2015 in southern Taiwan. The effects of the educational
intervention, including cervical cancer and Papanicolaou test knowledge,
attitudes towards cervical cancer, fatalism, barriers to receiving
Papani...περισσότερα »
Health Behaviors, Mental Health, and Health Care Utilization Among Single Mothers After Welfare Reforms in the 1990s
We studied the health of low-income US women
affected by the largest social policy change in recent US history: the 1996
welfare reforms. Using the Behavioral Risk Factor Surveillance System
(1993–2012), we performed 2 types of analysis. First, we used
difference-in-difference-in-differences analyses to estimate associations
between welfare reforms and health outcomes among the most affected women
(single mothers aged 18–64 years in 1997; *n* = 219,469) compared with less
affected women (married mothers, single nonmothers, and married nonmothers of
the same age range in 1997; *n* ...περισσότερα »
Basu et al. Respond to "Interdisciplinary Approach for Policy Evaluation"
from #Oncology via alexandrossfakianakis on
Inoreader http://ift.tt/1p87ylFvia IFTTT
Medavhengighetsdiagnosen
sfakianakisdiseasesστοHuman Diseases
Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete
72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1
ώρα
«Jeg er utslitt. Nå er jeg snart 81 år, og
ennå får jeg ikke fred», sa damen som ringte meg en sen kveldstime, skriver
Oddmund Harsvik. from #AlexandrosSfakianakis via Alexandros G.Sfakianakis on
Inoreader http://ift.tt/1VZVSvf via IFTTT
TBS Predict Coronary Artery Calcification in Adults
sfakianakisdiseasesστοHuman Diseases
Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete
72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1
ώρα
Purpose. This study analyzes the association
between the bony microarchitecture score (trabecular bone score, TBS) and
coronary artery calcification (CAC) in adults undergoing health exams. Materials
and Methods. We retrospectively collected subjects () who underwent coronary
computed tomography and bone mineral density studies simultaneously. CAC was
categorized to three levels (Group 0, G0, no CAC, […]
Insertion of Cochlear Implant Electrode Array Using the Underwater Technique for Preserving Residual Hearing.
Objective: To describe a method of cochlear
implantation in which the opening of the cochlea and the electrode array
insertion are performed under water (underwater technique). Study Design:
Retrospective patient review. Setting: Academic tertiary referral center.
Patients: Fifteen implantations in children and adult patients with residual
hearing at the frequencies 250, 500, and 1000 Hz on the unaided preoperative
pure-tone audiometry were included in this study. Intervention(s): Cochlear
implantation with a conventional full-length electrode, in which the opening of
the cochlea ...περισσότερα »
Long-lasting multifunctional CD8(+) T cell responses in end-stage melanoma patients can be induced by dendritic cell vaccination.
*Long-lasting multifunctional CD8(+) T cell
responses in end-stage melanoma patients can be induced by dendritic cell
vaccination.*Oncoimmunology. 2016;5(1):e1067745Authors: Wimmers F, Aarntzen EH,
Duiveman-deBoer T, Figdor CG, Jacobs JF, Tel J, de Vries IJAbstractCytotoxic T
cells are considered crucial for antitumor immunity and their induction is the
aim of various immunotherapeutic strategies. High frequencies of tumor-specific
CD8(+) T cells alone, however, are no guarantee for long-term tumor control.
Here, we analyzed the functionality of tumor-specific CD8(+) T cells
...περισσότερα »
Targeting TNF alpha as a novel strategy to enhance CD8(+) T cell-dependent immune response in melanoma?
*Targeting TNF alpha as a novel strategy to enhance
CD8(+) T cell-dependent immune response in melanoma?*Oncoimmunology.
2016;5(1):e1068495Authors: Bertrand F, Rochotte J, Colacios C, Montfort A,
Andrieu-Abadie N, Levade T, Benoist H, Ségui BAbstractTumor Necrosis Factor α
(TNF) is a pleiotropic cytokine exhibiting a dual activity in oncoimmunology,
either acting as a cytotoxic effector produced by leukocytes or behaving as an
immunosuppressive molecule. We have just discovered that TNF signaling impairs
the accumulation of tumor-infiltrating CD8(+) T lymphocytes in
experimen...περισσότερα »
Long-lasting multifunctional CD8(+) T cell responses in end-stage melanoma patients can be induced by dendritic cell vaccination.
*Long-lasting multifunctional CD8(+) T cell
responses in end-stage melanoma patients can be induced by dendritic cell
vaccination.*Oncoimmunology. 2016;5(1):e1067745Authors: Wimmers F, Aarntzen EH,
Duiveman-deBoer T, Figdor CG, Jacobs JF, Tel J, de Vries IJAbstractCytotoxic T
cells are considered crucial for antitumor immunity and their induction is the
aim of various immunotherapeutic strategies. High frequencies of tumor-specific
CD8(+) T cells alone, however, are no guarantee for long-term tumor control.
Here, we analyzed the functionality of tumor-specific CD8(+) T cells
...περισσότερα »
Targeting TNF alpha as a novel strategy to enhance CD8(+) T cell-dependent immune response in melanoma?
*Targeting TNF alpha as a novel strategy to enhance
CD8(+) T cell-dependent immune response in melanoma?*Oncoimmunology.
2016;5(1):e1068495Authors: Bertrand F, Rochotte J, Colacios C, Montfort A,
Andrieu-Abadie N, Levade T, Benoist H, Ségui BAbstractTumor Necrosis Factor α
(TNF) is a pleiotropic cytokine exhibiting a dual activity in oncoimmunology,
either acting as a cytotoxic effector produced by leukocytes or behaving as an
immunosuppressive molecule. We have just discovered that TNF signaling impairs
the accumulation of tumor-infiltrating CD8(+) T lymphocytes in
experimen...περισσότερα »
The extent to which melanoma alters tissue-resident dendritic cell function correlates with tumorigenicity.
*The extent to which melanoma alters
tissue-resident dendritic cell function correlates with tumorigenicity.*
Oncoimmunology. 2016;5(1):e1069462Authors: Hargadon KMAbstractWe have shown that
melanoma-derived factors alter the function of differentiated tissue-resident
dendritic cells (DC) in a tumorigenicity-dependent manner. Soluble factors,
including TGFβ1 and VEGF-A, contributed to dendritic cell dysfunction associated
with a highly-aggressive melanoma and conferred a phenotype upon DC likely to
favor immune escape and tumor outgrowth.PMID: 26942090 [PubMed - as supplied
...περισσότερα »
The extent to which melanoma alters tissue-resident dendritic cell function correlates with tumorigenicity.
*The extent to which melanoma alters
tissue-resident dendritic cell function correlates with tumorigenicity.*
Oncoimmunology. 2016;5(1):e1069462Authors: Hargadon KMAbstractWe have shown that
melanoma-derived factors alter the function of differentiated tissue-resident
dendritic cells (DC) in a tumorigenicity-dependent manner. Soluble factors,
including TGFβ1 and VEGF-A, contributed to dendritic cell dysfunction associated
with a highly-aggressive melanoma and conferred a phenotype upon DC likely to
favor immune escape and tumor outgrowth.PMID: 26942090 [PubMed - as supplied
...περισσότερα »
Aberrant excitatory rewiring of layer V pyramidal neurons early after neocortical trauma
Publication date: Available online 5 March
2016 Source:Neurobiology of Disease Author(s): D. Koji Takahashi, Feng Gu,
Isabel Parada, Shri Vyas, David A. Prince Lesioned neuronal circuits form new
functional connections after a traumatic brain injury (TBI). In humans and
animal models, aberrant excitatory connections that form after TBI may
contribute to the pathogenesis of post-traumatic… Continue reading Aberrant
excitatory rewiring of layer V pyramidal neurons early after neocortical
trauma
Editorial Board
Publication date: May 2016
Source:Neurobiology of Disease, Volume 89 from #Medicine-SfakianakisAlexandros
via o.lakala70 on Inoreader http://ift.tt/1Qzmkf5 via IFTTT
Prognostic factors after resection of colorectal liver metastases following preoperative second-line chemotherapy: Impact of RAS mutations
Publication date: Available online 5 March
2016 Source:European Journal of Surgical Oncology (EJSO) Author(s): Guillaume
Passot, Yun S. Chun, Scott E. Kopetz, Michael J. Overman, Claudius Conrad,
Thomas A. Aloia, Jean-Nicolas Vauthey BackgroundAfter resection of colorectal
liver metastases (CLM), RAS mutations are associated with modest survival
benefit and second-line chemotherapy confers limited hope for cure.ObjectiveTo…
Continue reading Prognostic factors after resection of colorectal liver
metastases following preoperative second-line chemotherapy: Impact of RAS
mutations
Beim Schilddrüsenkarzinom die richtige Therapie wählen
Welcher Tyrosinkinasehemmer? Welcher der
beiden zugelassenen Tyrosinkinasehemmer ist beim metastasierten medullären
Schilddrüsenkarzinom eher geeignet, den Krankheitsprogress aufzuhalten? Und wie
sollte das Vorgehen beim anaplastischen Karzinom sein? from
#Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader
http://ift.tt/1VZPVi0 via IFTTT
Mesenchymal Stem Cell-Derived Microvesicles Support Ex Vivo Expansion of Cord Blood-Derived CD34+ Cells
sfakianakisdiseasesστοHuman Diseases
Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete
72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1
ώρα
Mesenchymal stem cells (MSCs) are known to
support the characteristic properties of hematopoietic stem and progenitor cells
(HSPCs) in the bone marrow hematopoietic microenvironment. MSCs are used in
coculture systems as a feeder layer for the ex vivo expansion of umbilical cord
blood (CB) to increase the relatively low number of HSPCs in CB. Findings
[…]
Endogenous Generation of Singlet Oxygen and Ozone in Human and Animal Tissues: Mechanisms, Biological Significance, and Influence of Dietary Components
sfakianakisdiseasesστοHuman Diseases
Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete
72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1
ώρα
Recent studies have shown that exposing
antibodies or amino acids to singlet oxygen results in the formation of ozone
(or an ozone-like oxidant) and hydrogen peroxide and that human neutrophils
produce both singlet oxygen and ozone during bacterial killing. There is also
mounting evidence that endogenous singlet oxygen production may be a common
occurrence in […]
Long-Term Dynamics of Urban Soil Pollution with Heavy Metals in Moscow
sfakianakisdiseasesστοHuman Diseases
Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete
72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1
ώρα
Results of 21-year-long (1989–2010)
observations of the concentrations and the spatial distribution patterns of nine
heavy metals (HMs) in topsoils of the Eastern district of Moscow are presented.
The quantitative parameters of soil pollution include the annual increase rates
of HM concentrations in several land-use zones. The maps of geochemical
anomalies were compiled using the […]
Characterization of passive permeability at the blood–tumor barrier in five preclinical models of brain metastases of breast cancer
sfakianakisdiseasesστοHuman Diseases
Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete
72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1
ώρα
Abstract The blood–brain barrier (BBB) is
compromised in brain metastases, allowing for enhanced drug permeation into
brain. The extent and heterogeneity of BBB permeability in metastatic lesions is
important when considering the administration of chemotherapeutics. Since
permeability characteristics have been described in limited experimental models
of brain metastases, we sought to define these changes in […]
Effects of cyclopiazonic acid and dexamethasone on serotonin-induced calcium responses in vascular smooth muscle cells
sfakianakisdiseasesστοHuman Diseases
Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete
72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1
ώρα
Abstract We previously observed that
sarcoendoplasmic reticulum Ca2+ ATPase (SERCA) blockade by cyclopiazonic acid
(CPA) significantly potentiates serotonin (5-hydroxytryptamine (5-HT))-induced
vascular contractions. Furthermore, 5-HT receptor antagonist methysergide
partially inhibited CPA-potentiated 5-HT contractions. In the present study, we
further investigated whether SERCA inhibition potentiates 5-HT-induced Ca2+
responses along with attenuating the receptor antagonism by store-operated Ca2+
[…]
The extent to which melanoma alters tissue-resident dendritic cell function correlates with tumorigenicity.
*The extent to which melanoma alters
tissue-resident dendritic cell function correlates with tumorigenicity.*
Oncoimmunology. 2016;5(1):e1069462Authors: Hargadon KMAbstractWe have shown that
melanoma-derived factors alter the function of differentiated tissue-resident
dendritic cells (DC) in a tumorigenicity-dependent manner. Soluble factors,
including TGFβ1 and VEGF-A, contributed to dendritic cell dysfunction associated
with a highly-aggressive melanoma and conferred a phenotype upon DC likely to
favor immune escape and tumor outgrowth.PMID: 26942090 [PubMed - as supplied
...περισσότερα »
PD-1 expression conditions T cell avidity within an antigen-specific repertoire.
*PD-1 expression conditions T cell avidity within
an antigen-specific repertoire.*Oncoimmunology. 2016;5(1):e1104448Authors: Simon
S, Vignard V, Florenceau L, Dreno B, Khammari A, Lang F, Labarriere NAbstract
Despite its negative regulatory role on tumor-specific T cells, Programmed cell
death 1 (PD-1) is also a marker of activated tumor-infiltrating T cells. In
cancer, PD-1 blockade partially reverses T cell dysfunction allowing the
amplification of tumor reactive T cells. Here, we investigated the role of PD-1
signaling on effector/memory human T cells specific for shared m...περισσότερα »
PD-1 expression conditions T cell avidity within an antigen-specific repertoire.
*PD-1 expression conditions T cell avidity within
an antigen-specific repertoire.*Oncoimmunology. 2016;5(1):e1104448Authors: Simon
S, Vignard V, Florenceau L, Dreno B, Khammari A, Lang F, Labarriere NAbstract
Despite its negative regulatory role on tumor-specific T cells, Programmed cell
death 1 (PD-1) is also a marker of activated tumor-infiltrating T cells. In
cancer, PD-1 blockade partially reverses T cell dysfunction allowing the
amplification of tumor reactive T cells. Here, we investigated the role of PD-1
signaling on effector/memory human T cells specific for shared m...περισσότερα »
Density of tumor-infiltrating lymphocytes correlates with extent of brain edema and overall survival time in patients with brain metastases.
*Density of tumor-infiltrating lymphocytes
correlates with extent of brain edema and overall survival time in patients with
brain metastases.*Oncoimmunology. 2016;5(1):e1057388Authors: Berghoff AS, Fuchs
E, Ricken G, Mlecnik B, Bindea G, Spanberger T, Hackl M, Widhalm G, Dieckmann K,
Prayer D, Bilocq A, Heinzl H, Zielinski C, Bartsch R, Birner P, Galon J,
Preusser MAbstractThe immune microenvironment of the brain differs from that of
other organs and the role of tumor-infiltrating lymphocytes (TILs) in brain
metastases (BM), one of the most common and devastating complication
...περισσότερα »
Density of tumor-infiltrating lymphocytes correlates with extent of brain edema and overall survival time in patients with brain metastases.
*Density of tumor-infiltrating lymphocytes
correlates with extent of brain edema and overall survival time in patients with
brain metastases.*Oncoimmunology. 2016;5(1):e1057388Authors: Berghoff AS, Fuchs
E, Ricken G, Mlecnik B, Bindea G, Spanberger T, Hackl M, Widhalm G, Dieckmann K,
Prayer D, Bilocq A, Heinzl H, Zielinski C, Bartsch R, Birner P, Galon J,
Preusser MAbstractThe immune microenvironment of the brain differs from that of
other organs and the role of tumor-infiltrating lymphocytes (TILs) in brain
metastases (BM), one of the most common and devastating complication
...περισσότερα »
Favorable overall survival in stage III melanoma patients after adjuvant dendritic cell vaccination.
*Favorable overall survival in stage III melanoma
patients after adjuvant dendritic cell vaccination.*Oncoimmunology.
2016;5(1):e1057673Authors: Bol KF, Aarntzen EH, Hout FE, Schreibelt G, Creemers
JH, Lesterhuis WJ, Gerritsen WR, Grunhagen DJ, Verhoef C, Punt CJ, Bonenkamp JJ,
de Wilt JH, Figdor CG, de Vries IJAbstractMelanoma patients with regional
metastatic disease are at high risk for recurrence and metastatic disease,
despite radical lymph node dissection (RLND). We investigated the immunologic
response and clinical outcome to adjuvant dendritic cell (DC) vaccination
in...περισσότερα »
Density of tumor-infiltrating lymphocytes correlates with extent of brain edema and overall survival time in patients with brain metastases.
*Density of tumor-infiltrating lymphocytes
correlates with extent of brain edema and overall survival time in patients with
brain metastases.*Oncoimmunology. 2016;5(1):e1057388Authors: Berghoff AS, Fuchs
E, Ricken G, Mlecnik B, Bindea G, Spanberger T, Hackl M, Widhalm G, Dieckmann K,
Prayer D, Bilocq A, Heinzl H, Zielinski C, Bartsch R, Birner P, Galon J,
Preusser MAbstractThe immune microenvironment of the brain differs from that of
other organs and the role of tumor-infiltrating lymphocytes (TILs) in brain
metastases (BM), one of the most common and devastating complication
...περισσότερα »
Favorable overall survival in stage III melanoma patients after adjuvant dendritic cell vaccination.
*Favorable overall survival in stage III melanoma
patients after adjuvant dendritic cell vaccination.*Oncoimmunology.
2016;5(1):e1057673Authors: Bol KF, Aarntzen EH, Hout FE, Schreibelt G, Creemers
JH, Lesterhuis WJ, Gerritsen WR, Grunhagen DJ, Verhoef C, Punt CJ, Bonenkamp JJ,
de Wilt JH, Figdor CG, de Vries IJAbstractMelanoma patients with regional
metastatic disease are at high risk for recurrence and metastatic disease,
despite radical lymph node dissection (RLND). We investigated the immunologic
response and clinical outcome to adjuvant dendritic cell (DC) vaccination
in...περισσότερα »
Favorable overall survival in stage III melanoma patients after adjuvant dendritic cell vaccination.
*Favorable overall survival in stage III melanoma
patients after adjuvant dendritic cell vaccination.*Oncoimmunology.
2016;5(1):e1057673Authors: Bol KF, Aarntzen EH, Hout FE, Schreibelt G, Creemers
JH, Lesterhuis WJ, Gerritsen WR, Grunhagen DJ, Verhoef C, Punt CJ, Bonenkamp JJ,
de Wilt JH, Figdor CG, de Vries IJAbstractMelanoma patients with regional
metastatic disease are at high risk for recurrence and metastatic disease,
despite radical lymph node dissection (RLND). We investigated the immunologic
response and clinical outcome to adjuvant dendritic cell (DC) vaccination
in...περισσότερα »
Long-lasting multifunctional CD8(+) T cell responses in end-stage melanoma patients can be induced by dendritic cell vaccination.
*Long-lasting multifunctional CD8(+) T cell
responses in end-stage melanoma patients can be induced by dendritic cell
vaccination.*Oncoimmunology. 2016;5(1):e1067745Authors: Wimmers F, Aarntzen EH,
Duiveman-deBoer T, Figdor CG, Jacobs JF, Tel J, de Vries IJAbstractCytotoxic T
cells are considered crucial for antitumor immunity and their induction is the
aim of various immunotherapeutic strategies. High frequencies of tumor-specific
CD8(+) T cells alone, however, are no guarantee for long-term tumor control.
Here, we analyzed the functionality of tumor-specific CD8(+) T cells
...περισσότερα »
Targeting TNF alpha as a novel strategy to enhance CD8(+) T cell-dependent immune response in melanoma?
*Targeting TNF alpha as a novel strategy to enhance
CD8(+) T cell-dependent immune response in melanoma?*Oncoimmunology.
2016;5(1):e1068495Authors: Bertrand F, Rochotte J, Colacios C, Montfort A,
Andrieu-Abadie N, Levade T, Benoist H, Ségui BAbstractTumor Necrosis Factor α
(TNF) is a pleiotropic cytokine exhibiting a dual activity in oncoimmunology,
either acting as a cytotoxic effector produced by leukocytes or behaving as an
immunosuppressive molecule. We have just discovered that TNF signaling impairs
the accumulation of tumor-infiltrating CD8(+) T lymphocytes in
experimen...περισσότερα »
Long-lasting multifunctional CD8(+) T cell responses in end-stage melanoma patients can be induced by dendritic cell vaccination.
*Long-lasting multifunctional CD8(+) T cell
responses in end-stage melanoma patients can be induced by dendritic cell
vaccination.*Oncoimmunology. 2016;5(1):e1067745Authors: Wimmers F, Aarntzen EH,
Duiveman-deBoer T, Figdor CG, Jacobs JF, Tel J, de Vries IJAbstractCytotoxic T
cells are considered crucial for antitumor immunity and their induction is the
aim of various immunotherapeutic strategies. High frequencies of tumor-specific
CD8(+) T cells alone, however, are no guarantee for long-term tumor control.
Here, we analyzed the functionality of tumor-specific CD8(+) T cells
...περισσότερα »
Targeting TNF alpha as a novel strategy to enhance CD8(+) T cell-dependent immune response in melanoma?
*Targeting TNF alpha as a novel strategy to enhance
CD8(+) T cell-dependent immune response in melanoma?*Oncoimmunology.
2016;5(1):e1068495Authors: Bertrand F, Rochotte J, Colacios C, Montfort A,
Andrieu-Abadie N, Levade T, Benoist H, Ségui BAbstractTumor Necrosis Factor α
(TNF) is a pleiotropic cytokine exhibiting a dual activity in oncoimmunology,
either acting as a cytotoxic effector produced by leukocytes or behaving as an
immunosuppressive molecule. We have just discovered that TNF signaling impairs
the accumulation of tumor-infiltrating CD8(+) T lymphocytes in
experimen...περισσότερα »
Long-lasting multifunctional CD8(+) T cell responses in end-stage melanoma patients can be induced by dendritic cell vaccination.
*Long-lasting multifunctional CD8(+) T cell
responses in end-stage melanoma patients can be induced by dendritic cell
vaccination.*Oncoimmunology. 2016;5(1):e1067745Authors: Wimmers F, Aarntzen EH,
Duiveman-deBoer T, Figdor CG, Jacobs JF, Tel J, de Vries IJAbstractCytotoxic T
cells are considered crucial for antitumor immunity and their induction is the
aim of various immunotherapeutic strategies. High frequencies of tumor-specific
CD8(+) T cells alone, however, are no guarantee for long-term tumor control.
Here, we analyzed the functionality of tumor-specific CD8(+) T cells
...περισσότερα »
Targeting TNF alpha as a novel strategy to enhance CD8(+) T cell-dependent immune response in melanoma?
*Targeting TNF alpha as a novel strategy to enhance
CD8(+) T cell-dependent immune response in melanoma?*Oncoimmunology.
2016;5(1):e1068495Authors: Bertrand F, Rochotte J, Colacios C, Montfort A,
Andrieu-Abadie N, Levade T, Benoist H, Ségui BAbstractTumor Necrosis Factor α
(TNF) is a pleiotropic cytokine exhibiting a dual activity in oncoimmunology,
either acting as a cytotoxic effector produced by leukocytes or behaving as an
immunosuppressive molecule. We have just discovered that TNF signaling impairs
the accumulation of tumor-infiltrating CD8(+) T lymphocytes in
experimen...περισσότερα »
The extent to which melanoma alters tissue-resident dendritic cell function correlates with tumorigenicity.
*The extent to which melanoma alters
tissue-resident dendritic cell function correlates with tumorigenicity.*
Oncoimmunology. 2016;5(1):e1069462Authors: Hargadon KMAbstractWe have shown that
melanoma-derived factors alter the function of differentiated tissue-resident
dendritic cells (DC) in a tumorigenicity-dependent manner. Soluble factors,
including TGFβ1 and VEGF-A, contributed to dendritic cell dysfunction associated
with a highly-aggressive melanoma and conferred a phenotype upon DC likely to
favor immune escape and tumor outgrowth.PMID: 26942090 [PubMed - as supplied
...περισσότερα »
The extent to which melanoma alters tissue-resident dendritic cell function correlates with tumorigenicity.
*The extent to which melanoma alters
tissue-resident dendritic cell function correlates with tumorigenicity.*
Oncoimmunology. 2016;5(1):e1069462Authors: Hargadon KMAbstractWe have shown that
melanoma-derived factors alter the function of differentiated tissue-resident
dendritic cells (DC) in a tumorigenicity-dependent manner. Soluble factors,
including TGFβ1 and VEGF-A, contributed to dendritic cell dysfunction associated
with a highly-aggressive melanoma and conferred a phenotype upon DC likely to
favor immune escape and tumor outgrowth.PMID: 26942090 [PubMed - as supplied
...περισσότερα »
The extent to which melanoma alters tissue-resident dendritic cell function correlates with tumorigenicity.
*The extent to which melanoma alters
tissue-resident dendritic cell function correlates with tumorigenicity.*
Oncoimmunology. 2016;5(1):e1069462Authors: Hargadon KMAbstractWe have shown that
melanoma-derived factors alter the function of differentiated tissue-resident
dendritic cells (DC) in a tumorigenicity-dependent manner. Soluble factors,
including TGFβ1 and VEGF-A, contributed to dendritic cell dysfunction associated
with a highly-aggressive melanoma and conferred a phenotype upon DC likely to
favor immune escape and tumor outgrowth.PMID: 26942090 [PubMed - as supplied
...περισσότερα »
PD-1 expression conditions T cell avidity within an antigen-specific repertoire.
*PD-1 expression conditions T cell avidity within
an antigen-specific repertoire.*Oncoimmunology. 2016;5(1):e1104448Authors: Simon
S, Vignard V, Florenceau L, Dreno B, Khammari A, Lang F, Labarriere NAbstract
Despite its negative regulatory role on tumor-specific T cells, Programmed cell
death 1 (PD-1) is also a marker of activated tumor-infiltrating T cells. In
cancer, PD-1 blockade partially reverses T cell dysfunction allowing the
amplification of tumor reactive T cells. Here, we investigated the role of PD-1
signaling on effector/memory human T cells specific for shared m...περισσότερα »
PD-1 expression conditions T cell avidity within an antigen-specific repertoire.
*PD-1 expression conditions T cell avidity within
an antigen-specific repertoire.*Oncoimmunology. 2016;5(1):e1104448Authors: Simon
S, Vignard V, Florenceau L, Dreno B, Khammari A, Lang F, Labarriere NAbstract
Despite its negative regulatory role on tumor-specific T cells, Programmed cell
death 1 (PD-1) is also a marker of activated tumor-infiltrating T cells. In
cancer, PD-1 blockade partially reverses T cell dysfunction allowing the
amplification of tumor reactive T cells. Here, we investigated the role of PD-1
signaling on effector/memory human T cells specific for shared m...περισσότερα »
Reviving virus based cancer vaccines by using cytomegalovirus vectors expressing modified tumor antigens.
*Reviving virus based cancer vaccines by using
cytomegalovirus vectors expressing modified tumor antigens.*Oncoimmunology.
2016;5(1):e1056974Authors: Qiu Z, Grenier JM, Khanna KMAbstractCancer vaccines
that have utilized various immunization strategies to induce antitumor immunity
have largely failed in clinical settings. We have recently developed a cancer
vaccine using a cytomegalovirus (CMV) based vector that expressed a modified
melanoma antigen that elicited a robust antitumor CD8(+) T cell response and
tumor rejection.PMID: 26942064 [PubMed - as supplied by publisher]...περισσότερα »
Density of tumor-infiltrating lymphocytes correlates with extent of brain edema and overall survival time in patients with brain metastases.
*Density of tumor-infiltrating lymphocytes
correlates with extent of brain edema and overall survival time in patients with
brain metastases.*Oncoimmunology. 2016;5(1):e1057388Authors: Berghoff AS, Fuchs
E, Ricken G, Mlecnik B, Bindea G, Spanberger T, Hackl M, Widhalm G, Dieckmann K,
Prayer D, Bilocq A, Heinzl H, Zielinski C, Bartsch R, Birner P, Galon J,
Preusser MAbstractThe immune microenvironment of the brain differs from that of
other organs and the role of tumor-infiltrating lymphocytes (TILs) in brain
metastases (BM), one of the most common and devastating complication
...περισσότερα »
Favorable overall survival in stage III melanoma patients after adjuvant dendritic cell vaccination.
*Favorable overall survival in stage III melanoma
patients after adjuvant dendritic cell vaccination.*Oncoimmunology.
2016;5(1):e1057673Authors: Bol KF, Aarntzen EH, Hout FE, Schreibelt G, Creemers
JH, Lesterhuis WJ, Gerritsen WR, Grunhagen DJ, Verhoef C, Punt CJ, Bonenkamp JJ,
de Wilt JH, Figdor CG, de Vries IJAbstractMelanoma patients with regional
metastatic disease are at high risk for recurrence and metastatic disease,
despite radical lymph node dissection (RLND). We investigated the immunologic
response and clinical outcome to adjuvant dendritic cell (DC) vaccination
in...περισσότερα »
Long-lasting multifunctional CD8(+) T cell responses in end-stage melanoma patients can be induced by dendritic cell vaccination.
*Long-lasting multifunctional CD8(+) T cell
responses in end-stage melanoma patients can be induced by dendritic cell
vaccination.*Oncoimmunology. 2016;5(1):e1067745Authors: Wimmers F, Aarntzen EH,
Duiveman-deBoer T, Figdor CG, Jacobs JF, Tel J, de Vries IJAbstractCytotoxic T
cells are considered crucial for antitumor immunity and their induction is the
aim of various immunotherapeutic strategies. High frequencies of tumor-specific
CD8(+) T cells alone, however, are no guarantee for long-term tumor control.
Here, we analyzed the functionality of tumor-specific CD8(+) T cells
...περισσότερα »
Targeting TNF alpha as a novel strategy to enhance CD8(+) T cell-dependent immune response in melanoma?
*Targeting TNF alpha as a novel strategy to enhance
CD8(+) T cell-dependent immune response in melanoma?*Oncoimmunology.
2016;5(1):e1068495Authors: Bertrand F, Rochotte J, Colacios C, Montfort A,
Andrieu-Abadie N, Levade T, Benoist H, Ségui BAbstractTumor Necrosis Factor α
(TNF) is a pleiotropic cytokine exhibiting a dual activity in oncoimmunology,
either acting as a cytotoxic effector produced by leukocytes or behaving as an
immunosuppressive molecule. We have just discovered that TNF signaling impairs
the accumulation of tumor-infiltrating CD8(+) T lymphocytes in
experimen...περισσότερα »
The extent to which melanoma alters tissue-resident dendritic cell function correlates with tumorigenicity.
*The extent to which melanoma alters
tissue-resident dendritic cell function correlates with tumorigenicity.*
Oncoimmunology. 2016;5(1):e1069462Authors: Hargadon KMAbstractWe have shown that
melanoma-derived factors alter the function of differentiated tissue-resident
dendritic cells (DC) in a tumorigenicity-dependent manner. Soluble factors,
including TGFβ1 and VEGF-A, contributed to dendritic cell dysfunction associated
with a highly-aggressive melanoma and conferred a phenotype upon DC likely to
favor immune escape and tumor outgrowth.PMID: 26942090 [PubMed - as supplied
...περισσότερα »
PD-1 expression conditions T cell avidity within an antigen-specific repertoire.
*PD-1 expression conditions T cell avidity within
an antigen-specific repertoire.*Oncoimmunology. 2016;5(1):e1104448Authors: Simon
S, Vignard V, Florenceau L, Dreno B, Khammari A, Lang F, Labarriere NAbstract
Despite its negative regulatory role on tumor-specific T cells, Programmed cell
death 1 (PD-1) is also a marker of activated tumor-infiltrating T cells. In
cancer, PD-1 blockade partially reverses T cell dysfunction allowing the
amplification of tumor reactive T cells. Here, we investigated the role of PD-1
signaling on effector/memory human T cells specific for shared m...περισσότερα »
Fwd: Journal of International Pathology and Clinical Medicine, Year 2015, Issue 12 -New Issue Alert.
From: order@email.oriprobe.comDate: March 06, 2016
at 08:08AM[image: 1PHav7d]New Issue TOC Alert*Dear Valued Customer*, [image:
1SchPFA] We are pleased to deliver your requested table of contents alert for
*Journal of International Pathology and Clinical Medicine*. Year *2015* Issue
*12* is now available on CAOD.*In this issue:*ame news| zuo zui hao de zi ji !
qian shou en ze ,ame college ta shang xin zheng cheng (AME News|做最好的自己!牵手恩泽,AME
College踏上新征程)LI Mei...... page:2027-2028ame pubmed shi yong ji qiao | ru he da
zao pubmed ge ren zhuan shu lv qi ? (AME PubMed实用技巧|...περισσότερα »
Fwd: Military Medical Journal of South China, Year 2016, Issue 01 -New Issue Alert.
From: order@email.oriprobe.comDate: March 06, 2016
at 08:08AM[image: 1PHav7d]New Issue TOC Alert*Dear Valued Customer*, [image:
1SchPFA] We are pleased to deliver your requested table of contents alert for
*Military Medical Journal of South China*. Year *2016* Issue *01* is now
available on CAOD.*In this issue:*Target Effect of Murine MicroRNA-135a and
STAT6 in Rats in Vitro (小鼠microRNA-135a与STAT6靶点作用的体外研究)LUO Yan-yun, YANG Guang,
ZHANG Zhao, CHEN Rui-yao, TAO Ze-zhang, Department of Otolaryngology, Wuhan
General Hospital of Guangzhou Command...... page:1-4+13hua nan ...περισσότερα »
The thyroid hormone triiodothyronine reinvigorates dendritic cells and potentiates anti-tumor immunity.
*The thyroid hormone triiodothyronine reinvigorates
dendritic cells and potentiates anti-tumor immunity.*Oncoimmunology.
2016;5(1):e1064579Authors: Alamino VA, Montesinos MM, Rabinovich GA, Pellizas CG
AbstractDendritic cell (DC) cancer vaccines have shown limited clinical benefit.
Thus, the identification of signals and molecular pathways that potentiate the
immunogenicity of DCs has become a major challenge in cancer research. Our
studies demonstrate that triiodothyronine endows DCs with enhanced ability to
stimulate cytotoxic T-cell responses with implications in DC-based i...περισσότερα »
Fwd: Shanghai Medical Imaging, Year 2015, Issue 04 -New Issue Alert.
From: order@email.oriprobe.comDate: March 06, 2016
at 08:08AM[image: 1PHav7d]New Issue TOC Alert*Dear Valued Customer*, [image:
1SchPFA] We are pleased to deliver your requested table of contents alert for
*Shanghai Medical Imaging*. Year *2015* Issue *04* is now available on CAOD.*In
this issue:*Pediatric thyroid cancers and the value of ultrasound in diagnosis
of pediatric thyroid cancers (青少年甲状腺癌及超声对其诊断的应用价值)DONG Yijie, ZHAN Weiwei,
Department of Ultrasound, Ruijin Hospital, Shanghai Jiao Tong University School
of Medicine...... page:241-247Differential diagnosis of...περισσότερα »
Fwd: Chinese Journal of Interventional Imaging and Therapy, Year 2016, Issue 02 -New Issue Alert.
From: order@email.oriprobe.comDate: March 06, 2016
at 08:07AM[image: 1PHav7d]New Issue TOC Alert*Dear Valued Customer*, [image:
1SchPFA] We are pleased to deliver your requested table of contents alert for
*Chinese Journal of Interventional Imaging and Therapy*. Year *2016* Issue *02*
is now available on CAOD.*In this issue:*Application of breathing control with
positioning needle in CT-guided percutaneous puncture for pulmonary small
lesions near diaphragm ("呼吸针控"在CT引导下经皮肺穿刺近膈小病灶中的应用)ZHENG Yujing, WU Qingde, MENG
Liyan, Department of Radiology, Shunde Chinese Medicine...περισσότερα »
Chinese Journal of Pharmaceutical Analysis, Year 2016, Issue 01 -New Issue Alert.
medicinesfakianakisστοMedicine by
Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel
:00302841026182 & 00306932607174Πριν από 1 ώρα
From: order@email.oriprobe.com Date: March
06, 2016 at 08:09AM New Issue TOC Alert Dear Valued Customer, We are pleased to
deliver your requested table of contents alert for Chinese Journal of
Pharmaceutical Analysis. Year 2016 Issue 01 is now available on CAOD. In this
issue: Research progress of pharmacodynamics and toxicity of traditional Chinese
medicine based […]
Cancer Frontier, Year 2015, Issue 06 -New Issue Alert.
medicinesfakianakisστοMedicine by
Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel
:00302841026182 & 00306932607174Πριν από 1 ώρα
From: order@email.oriprobe.com Date: March
06, 2016 at 08:08AM New Issue TOC Alert Dear Valued Customer, We are pleased to
deliver your requested table of contents alert for Cancer Frontier. Year 2015
Issue 06 is now available on CAOD. In this issue: gong jian fang ai kang ai de
ying yang fang xian (共建防癌抗癌的营养防线) YU Kang […]
Medicine and Pharmacy of Yunnan, Year 2015, Issue 06 -New Issue Alert.
medicinesfakianakisστοMedicine by
Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel
:00302841026182 & 00306932607174Πριν από 1 ώρα
From: order@email.oriprobe.com Date: March
06, 2016 at 08:08AM New Issue TOC Alert Dear Valued Customer, We are pleased to
deliver your requested table of contents alert for Medicine and Pharmacy of
Yunnan. Year 2015 Issue 06 is now available on CAOD. In this issue: yun nan yi
yao 2015 nian di 36 juan zong mu […]
Stomatology, Year 2016, Issue 01 -New Issue Alert.
medicinesfakianakisστοMedicine by
Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel
:00302841026182 & 00306932607174Πριν από 1 ώρα
From: order@email.oriprobe.com Date: March
06, 2016 at 08:08AM New Issue TOC Alert Dear Valued Customer, We are pleased to
deliver your requested table of contents alert for Stomatology. Year 2016 Issue
01 is now available on CAOD. In this issue: Periodontally accelerated osteogenic
orthodontics (牙周辅助加速成骨正畸治疗技术) WANG Lin, Jiangsu Key Laboratory of Oral Diseases,
Department of […]
Journal of Clinical Radiology, Year 2015, Issue 12 -New Issue Alert.
medicinesfakianakisστοMedicine by
Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel
:00302841026182 & 00306932607174Πριν από 1 ώρα
From: order@email.oriprobe.com Date: March
06, 2016 at 08:08AM New Issue TOC Alert Dear Valued Customer, We are pleased to
deliver your requested table of contents alert for Journal of Clinical
Radiology. Year 2015 Issue 12 is now available on CAOD. In this issue: song guo
ti qu lei yuan xing ying qing fen xi bing […]
Clinical Focus, Year 2016, Issue 02 -New Issue Alert.
medicinesfakianakisστοMedicine by
Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel
:00302841026182 & 00306932607174Πριν από 1 ώρα
From: order@email.oriprobe.com Date: March
06, 2016 at 08:08AM New Issue TOC Alert Dear Valued Customer, We are pleased to
deliver your requested table of contents alert for Clinical Focus. Year 2016
Issue 02 is now available on CAOD. In this issue: lin chuang zuo zuo tou gao xu
zhi (《临床荟萃》投稿须知) …… page:112 ben kan chuang […]
Fwd: Medicine and Pharmacy of Yunnan, Year 2015, Issue 06 -New Issue Alert.
Alexandros G. SfakianakisστοChina/Asia Medicine on
Demand (CAOD) by Alexandros G.SfakianakisΠριν από 1 ώρα
From: order@email.oriprobe.comDate: March 06, 2016
at 08:08AMNew Issue TOC Alert*Dear Valued Customer*, We are pleased to deliver
your requested table of contents alert for *Medicine and Pharmacy of Yunnan*.
Year *2015* Issue *06* is now available on CAOD.*In this issue:*yun nan yi yao
2015 nian di 36 juan zong mu lu (《云南医药》2015年第36卷总目录)...... page:1-10yun nan yi
yao 2015 nian di 36 juan guan jian ci suo yin (《云南医药》2015年第36卷关键词索引)......
page:1-6Observation on dose-effect relationship of umbilical cord mesenchymal
stem cells treatment for patients with systemic lupus...περισσότερα »
Fwd: Pharmacy Today , Year 2016, Issue 01 -New Issue Alert.
Alexandros G. SfakianakisστοChina/Asia Medicine on
Demand (CAOD) by Alexandros G.SfakianakisΠριν από 1 ώρα
From: order@email.oriprobe.comDate: March 06, 2016
at 08:08AMNew Issue TOC Alert*Dear Valued Customer*, We are pleased to deliver
your requested table of contents alert for *Pharmacy Today* . Year *2016* Issue
*01* is now available on CAOD.*In this issue:*guan yu yin fa chang wai ying yang
lin chuang yao xue gong shi de tong zhi (关于印发《肠外营养临床药学共识》的通知)...... page:1-14xin
chun ji yu (新春寄语)CHEN Minxi...... page:2guo yao kong gu guang zhou you xian gong
si (国药控股广州有限公司)...... page:3Chemical Constituents from Diphylleia Sinesis
(江边一碗水的化学成分研究)JIANG Jie, LIU Yong, QIN Shu...περισσότερα »
Fwd: Journal of International Pathology and Clinical Medicine, Year 2015, Issue 12 -New Issue Alert.
Alexandros G. SfakianakisστοChina/Asia Medicine on
Demand (CAOD) by Alexandros G.SfakianakisΠριν από 1 ώρα
From: order@email.oriprobe.comDate: March 06, 2016
at 08:08AMNew Issue TOC Alert*Dear Valued Customer*, We are pleased to deliver
your requested table of contents alert for *Journal of International Pathology
and Clinical Medicine*. Year *2015* Issue *12* is now available on CAOD.*In this
issue:*ame news| zuo zui hao de zi ji ! qian shou en ze ,ame college ta shang
xin zheng cheng (AME News|做最好的自己!牵手恩泽,AME College踏上新征程)LI Mei......
page:2027-2028ame pubmed shi yong ji qiao | ru he da zao pubmed ge ren zhuan shu
lv qi ? (AME PubMed实用技巧|如何打造PubMed个人专属滤器?)CHEN Shuo, MAO...περισσότερα »
Long non-coding RNA-Low Expression in Tumor inhibits the invasion and metastasis of esophageal squamous cell carcinoma by regulating p53 expression.
Alexandros G. SfakianakisστοHead,Neck,Brain,Cervical Spine and Esophageal Cancers by Alexandros
G. SfakianakisΠριν από 1 ώρα
Authors: Wang PL, Liu B, Xia Y, Pan CF, Ma T, Chen
YJ Abstract Long non-coding RNAs (lncRNAs) are involved in governing fundamental
biological processes, and, in many lncRNAs, the expression level is altered and
likely to have a functional role in tumorigenesis, including apoptosis,
migration and invasion. The lncRNA‑Low Expression in Tumor (LET), a recently
identified lncRNA, was demonstrated to be downregulated in hepatocellular and
gallbladder cancer. However, its role in esophageal squamous cell carcinoma
(ESCC) requires investigation. The expression level of lncRNA‑LET mRNA
i...περισσότερα »
Secreted recombinant human IL-24 protein inhibits the proliferation of esophageal squamous cell carcinoma Eca-109 cells in vitro and in vivo.
Alexandros G. SfakianakisστοHead,Neck,Brain,Cervical Spine and Esophageal Cancers by Alexandros
G. SfakianakisΠριν από 1 ώρα
Authors: Ma Q, Jin B, Zhang Y, Shi Y, Zhang C, Luo
D, Wang P, Duan C, Song H, Li X, Deng X, Chen Z, Wang Z, Jiang H, Liu Y Abstract
Interleukin-24 (IL-24) displays cancer-specific apoptosis-inducing properties in
a broad spectrum of human tumors without harmful effects on normal cells. The
human IL-24 protein is secreted as a glycosylated protein and functions as a
pro-Th1 cytokine and a potent antiangiogenic molecule. However, the function of
secreted recombinant human IL-24 (srhIL-24) protein in esophageal squamous cell
carcinoma (ESCC) cells has not been studied. In the present...περισσότερα »
The role of cofilin-l in vulvar squamous cell carcinoma: A marker of carcinogenesis, progression and targeted therapy.
Alexandros G. SfakianakisστοHead,Neck,Brain,Cervical Spine and Esophageal Cancers by Alexandros
G. SfakianakisΠριν από 1 ώρα
Authors: Wu Q, Jiang Y, Cui S, Wang Y, Wu X
Abstract Numerous studies have revealed that cofilin-l (CFL1) is associated with
cancer cell migration and invasion in various types of tumor tissues. We
investigated the roles of CFL1 in vulvar squamous cell carcinoma (VSCC). CFL1
expression was detected in VSCC and normal vulvar tissues using
immunohistochemistry and western blotting. The vulvar carcinoma SW962 cell line
was transfected with CFL1 small interfering RNA (siRNA) and exposed to
periplocoside. We then assessed changes in cell proliferation, apoptosis,
invasion and metastasis...περισσότερα »
Long non-coding RNA-Low Expression in Tumor inhibits the invasion and metastasis of esophageal squamous cell carcinoma by regulating p53 expression.
Alexandros G. SfakianakisστοHead,Neck,Brain,Cervical Spine and Esophageal Cancers by Alexandros
G. SfakianakisΠριν από 1 ώρα
Authors: Wang PL, Liu B, Xia Y, Pan CF, Ma T, Chen
YJ Abstract Long non-coding RNAs (lncRNAs) are involved in governing fundamental
biological processes, and, in many lncRNAs, the expression level is altered and
likely to have a functional role in tumorigenesis, including apoptosis,
migration and invasion. The lncRNA‑Low Expression in Tumor (LET), a recently
identified lncRNA, was demonstrated to be downregulated in hepatocellular and
gallbladder cancer. However, its role in esophageal squamous cell carcinoma
(ESCC) requires investigation. The expression level of lncRNA‑LET mRNA
i...περισσότερα »
Congenital Stapes Ankylosis in Children: Surgical Findings and Results in 35 Cases.
Objective: To evaluate surgical findings and
hearing results in children undergoing middle ear surgery for congenital stapes
ankylosis with or without other ossicular malformations (Teunissen and Cremers
class I and class II malformations). Study Design: A nonrandomized, nonblinded
case series of prospectively collected data. Setting: A tertiary referral
center. Patients: Twenty-eight consecutive pediatric patients who underwent 35
surgical procedures for congenital stapes ankylosis with or without other
ossicular malformations and had available postoperative pure-tone audiometry.
I...περισσότερα »
Assessment of Vestibulo-oculomotor Reflex in Meniere's Disease: Defining an Instrumental Profile.
Objectives: To analyze and compare, in two groups
of patients affected by definite Meniere's disease (MD) but treated differently,
the Video Head Impulse Test findings especially by putting them in relationship
with canal paresis, hearing loss, and duration of the disease. Study Design:
Retrospective chart review. Patients: Seventy patients affected by unilateral
definite MD (16 in Group 1 and 54 in Group 2) observed between March 2014 and
May 2015 in a tertiary referral center were retrospectively studied and then
divided into two groups: Group 1 was previously treated with intraty...περισσότερα »
Comparison of Middle Ear Visualization With Endoscopy and Microscopy.
Introduction: The primary goal of chronic ear
surgery is the creation of a safe, clean dry ear. For cholesteatomas, complete
removal of disease is dependent on visualization. Conventional microscopy is
adequate for most dissection, but various subregions of the middle ear are
better visualized with endoscopy. Objective: The purpose of the present study
was to quantitatively assess the improved visualization that endoscopes afford
as compared with operating microscopes. Methods: Microscopic and endoscopic
views were simulated using a three-dimensional model developed from temporal
bo...περισσότερα »
Insertion of Cochlear Implant Electrode Array Using the Underwater Technique for Preserving Residual Hearing.
Objective: To describe a method of cochlear
implantation in which the opening of the cochlea and the electrode array
insertion are performed under water (underwater technique). Study Design:
Retrospective patient review. Setting: Academic tertiary referral center.
Patients: Fifteen implantations in children and adult patients with residual
hearing at the frequencies 250, 500, and 1000 Hz on the unaided preoperative
pure-tone audiometry were included in this study. Intervention(s): Cochlear
implantation with a conventional full-length electrode, in which the opening of
the cochlea an...περισσότερα »
Fwd: Military Medical Journal of South China, Year 2016, Issue 01 -New Issue Alert.
Alexandros G. SfakianakisστοChina/Asia Medicine on
Demand (CAOD) by Alexandros G.SfakianakisΠριν από 1 ώρα
From: order@email.oriprobe.comDate: March 06, 2016
at 08:08AMNew Issue TOC Alert*Dear Valued Customer*, We are pleased to deliver
your requested table of contents alert for *Military Medical Journal of South
China*. Year *2016* Issue *01* is now available on CAOD.*In this issue:*Target
Effect of Murine MicroRNA-135a and STAT6 in Rats in Vitro
(小鼠microRNA-135a与STAT6靶点作用的体外研究)LUO Yan-yun, YANG Guang, ZHANG Zhao, CHEN
Rui-yao, TAO Ze-zhang, Department of Otolaryngology, Wuhan General Hospital of
Guangzhou Command...... page:1-4+13hua nan guo fang yi xue za zhi gao yue
(《...περισσότερα »
Fwd: Space Medicine & Medical Engineering, Year 2016, Issue 01 -New Issue Alert.
Alexandros G. SfakianakisστοChina/Asia Medicine on
Demand (CAOD) by Alexandros G.SfakianakisΠριν από 1 ώρα
From: order@email.oriprobe.comDate: March 06, 2016
at 08:08AMNew Issue TOC Alert*Dear Valued Customer*, We are pleased to deliver
your requested table of contents alert for *Space Medicine & Medical
Engineering*. Year *2016* Issue *01* is now available on CAOD.*In this issue:*
Qiang Gu Kang Wei Prescription Increases Bone Mineral Density of Load-bearing
Bone in Tail Suspended Rats (强骨抗萎方增强尾吊大鼠承重骨骨矿密度（英文）)Li Dijie, Chen Zhihao, Liu
Zonglin, Lin Yu, Ding Chong, Zhao Fan, Arfat Yasir, Hu Lifang, Li Yongzhi, Shang
Peng, Qian Airong, Key Laboratory for Space Biosciences & Bi...περισσότερα »
Fwd: Stomatology, Year 2016, Issue 01 -New Issue Alert.
Alexandros G. SfakianakisστοChina/Asia Medicine on
Demand (CAOD) by Alexandros G.SfakianakisΠριν από 1 ώρα
From: order@email.oriprobe.comDate: March 06, 2016
at 08:08AMNew Issue TOC Alert*Dear Valued Customer*, We are pleased to deliver
your requested table of contents alert for *Stomatology*. Year *2016* Issue *01*
is now available on CAOD.*In this issue:*Periodontally accelerated osteogenic
orthodontics (牙周辅助加速成骨正畸治疗技术)WANG Lin, Jiangsu Key Laboratory of Oral Diseases,
Department of Orthodontics, Affiliated Hospital of Stomatology, Nanjing Medical
University...... page:1-5feng zheng fan man , meng yi qi hang zhu bian ji yu
(风正帆满,梦已起航——主编寄语)WANG Lin...... page:3Effects o...περισσότερα »
Fwd: Journal of Clinical Radiology, Year 2015, Issue 12 -New Issue Alert.
Alexandros G. SfakianakisστοChina/Asia Medicine on
Demand (CAOD) by Alexandros G.SfakianakisΠριν από 1 ώρα
From: order@email.oriprobe.comDate: March 06, 2016
at 08:08AMNew Issue TOC Alert*Dear Valued Customer*, We are pleased to deliver
your requested table of contents alert for *Journal of Clinical Radiology*. Year
*2015* Issue *12* is now available on CAOD.*In this issue:*song guo ti qu lei
yuan xing ying qing fen xi bing bian xing zhi (松果体区类圆形影——请分析病变性质)LIANG Zuo, TAO
Jingxiong, LI Zhen, WANG Jia, DU Bailin...... page:1873+2026Altered Degree
Centrality Measured by Resting State f MRI in Mild Traumatic Brain Injury
(轻型脑外伤患者脑网络中心度改变的静息态fMRI研究)XIE Kai, GAO Lei, LI Jian, De...περισσότερα »
Fwd: Clinical Focus, Year 2016, Issue 02 -New Issue Alert.
Alexandros G. SfakianakisστοChina/Asia Medicine on
Demand (CAOD) by Alexandros G.SfakianakisΠριν από 1 ώρα
From: order@email.oriprobe.comDate: March 06, 2016
at 08:08AMNew Issue TOC Alert*Dear Valued Customer*, We are pleased to deliver
your requested table of contents alert for *Clinical Focus*. Year *2016* Issue
*02* is now available on CAOD.*In this issue:*lin chuang zuo zuo tou gao xu zhi
(《临床荟萃》投稿须知)...... page:112ben kan chuang ban men hu wang zhan (本刊创办门户网站)......
page:116Advances in clinical researches on cerebrovascular diseases in 2015
(2015年脑血管病临床进展)Zhang Yusheng, Chen Yunyu, Chen Danxia, Dong Dawei, Mai
Hongcheng, Xu Anding, Department of Neurology and Strok...περισσότερα »
Doubling the blockade for melanoma immunotherapy.
*Doubling the blockade for melanoma immunotherapy.*
Oncoimmunology. 2016;5(1):e1106127Authors: Galluzzi L, Eggermont A, Kroemer G
PMID: 26942094 [PubMed - as supplied by publisher]from melanoma2 via als.fakia
on Inoreader http://ift.tt/21PZqnzvia IFTTTfrom #Med Blogs by Alexandros
G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1TXrsvRvia
IFTTT
First oncolytic virus approved for melanoma immunotherapy.
*First oncolytic virus approved for melanoma
immunotherapy.*Oncoimmunology. 2016;5(1):e1115641Authors: Pol J, Kroemer G,
Galluzzi LAbstractOn 2015, October 27th, the US Food and Drug Administration
(FDA) has officially approved talimogene laherparepvec (T-VEC, also known as
OncoVEX(GM-CSF)) for use in melanoma patients with injectable but non-resectable
lesions in the skin and lymph nodes. T-VEC (which is commercialized by Amgen,
Inc. under the name of Imlygic®) becomes therefore the first oncolytic virus
approved for cancer therapy in the US.PMID: 26942095 [PubMed - as
supp...περισσότερα »
PD-1 expression conditions T cell avidity within an antigen-specific repertoire.
*PD-1 expression conditions T cell avidity within
an antigen-specific repertoire.*Oncoimmunology. 2016;5(1):e1104448Authors: Simon
S, Vignard V, Florenceau L, Dreno B, Khammari A, Lang F, Labarriere NAbstract
Despite its negative regulatory role on tumor-specific T cells, Programmed cell
death 1 (PD-1) is also a marker of activated tumor-infiltrating T cells. In
cancer, PD-1 blockade partially reverses T cell dysfunction allowing the
amplification of tumor reactive T cells. Here, we investigated the role of PD-1
signaling on effector/memory human T cells specific for shared m...περισσότερα »
Intraosseous schwannoma localized in the anterior mandible with multilocular radiolucency: A case report
Publication date: Available online 5 March 2016
*Source:*Oral Science InternationalAuthor(s): Yasuhiro Kawasaki, Hironobu
Kobashi, Syouichirou Ishii, Noboru YakushijiIntraosseous schwannoma in the oral
and maxillofacial regions is rare. It arises most commonly in the posterior
region of the mandible due to the presence of the inferior alveolar nerve. There
have been only seven reported cases of intraosseous schwannoma localized in the
anterior region of the mandible, all of which involved unilocular radiolucency.
In this study, we report the rare case of an intraosseous schwannoma...περισσότερα »
Comparison of Reconstruction Algorithms for Decreasing the Exposure Dose During Digital Tomosynthesis for Arthroplasty: a Phantom Study
Abstract To explore the possibility of decreasing
the radiation dose during digital tomosynthesis (DT) for arthroplasty, we
compared the image qualities of several reconstruction algorithms, such as
filtered back projection (FBP) and two iterative reconstruction (IR), methods
maximum likelihood expectation maximization (MLEM) and the simultaneous
iterative reconstruction technique (SIRT) under different radiation doses. The
three algorithms were implemented using a DT system and experimentally evaluated
by contrast-to-noise ratio (CNR), artifact spread function (ASF), and power
sp...περισσότερα »
Patient with chronic renal failure undergoing surgery.
Purpose of review: Chronic kidney disease (CKD) is
an increasing health problem worldwide and is associated with a number of
clinical challenges. In this paper, we review recent studies that deal with
strategies for the management of patients with CKD undergoing surgery. Recent
findings: Effective strategies for nephroprotection are crucial for the handling
of patients with CKD in the perioperative setting to prevent complications and
to avoid the progression of CKD. Due to the lack of perioperative studies with
CKD patients there are only level 2 recommendations. First of all,
th...περισσότερα »
Amniotic fluid embolism: update and review.
Purpose of review: This article reviews our current
understanding of amniotic fluid embolism (AFE), specifically the pathogenesis,
treatment strategies, potential diagnostic tests and future therapeutic
interventions for AFE. Recent findings: The incidence and case mortality of AFE
varies widely because of heterogeneous diagnostic criteria and varying reporting
mechanisms across the world. Amniotic fluid embolism is thought to be caused by
abnormal activation of immunologic mechanisms following entry of fetal antigens
into maternal circulation. Mast cell degranulation and compleme...περισσότερα »
Adverse events of postoperative thoracic epidural analgesia, a retrospective analysis of 7273 cases in a tertiary care teaching hospital.
BACKGROUND: Thoracic epidural analgesia is a well
established technique for postoperative pain relief after major abdominal and
thoracic surgery. Safety remains a major concern because of serious adverse
events including epidural haematoma, abscess and permanent neurological deficit.
OBJECTIVE: The aim of this study was to evaluate the incidence and the long-term
outcome of serious adverse events associated with thoracic epidural analgesia.
DESIGN: Retrospective cohort study. SETTING: The study was conducted at a single
institution, a tertiary care teaching hospital. Data were col...περισσότερα »
Reply to: postoperative shoulder pain after laparoscopic hysterectomy with deep neuromuscular blockade and low-pressure pneumoperitoneum.
No abstract availablefrom #Head and Neck by
Sfakianakis via simeraentaxei on Inoreader http://ift.tt/1Yh8ek8via IFTTTfrom
#Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader
http://ift.tt/1noPfXkvia IFTTT
Intraoperative hypotension is associated with myocardial damage in noncardiac surgery: An observational study.
BACKGROUND: Perioperative myocardial damage and
infarction (MI) is associated with increased mortality and other postoperative
complications. OBJECTIVES: To assess the incidence of perioperative myocardial
damage in patients undergoing major elective noncardiac surgery, to elucidate
any association with postoperative MI and mortality and to estimate the impact
of preoperative risk factors and intraoperative hypotension. DESIGN:
Observational cohort study. SETTING: Karolinska University Hospital, Stockholm,
Sweden, from October 2012 to May 2013. PATIENTS: In this single-centre
stud...περισσότερα »
Satisfaction and safety using dexmedetomidine or propofol sedation during endoscopic oesophageal procedures: A randomised controlled trial.
BACKGROUND: Dexmedetomidine possesses anxiolytic
and hypnotic properties without respiratory side-effects, making it
theoretically an ideal sedative agent for endoscopic procedures. OBJECTIVE: We
aimed to compare satisfaction and safety among outpatients receiving sedation
with dexmedetomidine or propofol for endoscopic oesophageal procedures. DESIGN:
A randomised controlled study. SETTING: Endoscopic intervention suite at the
Academic Medical Centre in Amsterdam, Netherlands. PARTICIPANTS: Patients aged
at least 18 years, and American Society of Anesthesiologists' physical
status...περισσότερα »
Anaesthesia for orphan disease: Rocuronium and sugammadex in the anaesthetic management of a parturient with Becker’s myotonia congenita.
No abstract availablefrom #Head and Neck by
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Transcutaneous vocal cord ultrasonography after oral and maxillofacial surgery requiring intermaxillary fixation: A technical report.
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Patient with chronic renal failure undergoing surgery.
Purpose of review: Chronic kidney disease (CKD) is
an increasing health problem worldwide and is associated with a number of
clinical challenges. In this paper, we review recent studies that deal with
strategies for the management of patients with CKD undergoing surgery. Recent
findings: Effective strategies for nephroprotection are crucial for the handling
of patients with CKD in the perioperative setting to prevent complications and
to avoid the progression of CKD. Due to the lack of perioperative studies with
CKD patients there are only level 2 recommendations. First of all,
this...περισσότερα »
People’s Military Surgeon, Year 2016, Issue 02 -New Issue Alert.
From: order@email.oriprobe.comDate: March 06, 2016
at 08:08AM[image: 1PHav7d]New Issue TOC Alert*Dear Valued Customer*,[image:
1SchPFA] We are pleased to deliver your requested table of contents alert for
*People's Military Surgeon*. Year *2016* Issue *02* is now available on CAOD.
*In this issue:* PEOPLE'S MILITARY MEDICAL PRESS (人民軍醫出版社)…… page:105tian jin
gang te bie zhong da huo zai bao zha shi gu yi xue jiu yuan de zuo fa yu si kao
(天津港特别重大火灾爆炸事故医学救援的做法与思考)WANG Jun, CAO Min, XIE Ming, DONG Junjie…… page:111-113
zhong yao ti xing (重要提醒)BEN Kanbianjibu…… page:113z...περισσότερα »
Chinese Journal of Cellular and Molecular Immunology, Year 2016, Issue 01 -New Issue Alert.
From: order@email.oriprobe.comDate: March 06, 2016
at 08:08AM[image: 1PHav7d]New Issue TOC Alert*Dear Valued Customer*,[image:
1SchPFA] We are pleased to deliver your requested table of contents alert for
*Chinese Journal of Cellular and Molecular Immunology*. Year *2016* Issue *01*
is now available on CAOD. *In this issue:* Domestication of suspension CHO cells
and its application in the expression of anti-PSMA antibody
(悬浮驯化CHO细胞并用于抗前列腺特异性膜抗原的抗体表达)WU Jieheng, HAN Donghui, WEI Ming, ZHENG Guoxu,
JIAO Dian, XI Wenjin, YANG Angang, QIN Weijun, WEN Weihong, Department of
Im...περισσότερα »
Chinese Journal of Health Laboratory Technology, Year 2016, Issue 02 -New Issue Alert.
From: order@email.oriprobe.comDate: March 06, 2016
at 08:07AM[image: 1PHav7d]New Issue TOC Alert*Dear Valued Customer*,[image:
1SchPFA] We are pleased to deliver your requested table of contents alert for
*Chinese Journal of Health Laboratory Technology*. Year *2016* Issue *02* is now
available on CAOD. *In this issue:* Simultaneous determination of 6 triazole
fungicides in drinking water by UPLC- MS/MS (超高效液相色谱-串联质谱法测定饮用水中6种三唑类杀菌剂)ZHUANG
Qian-kun, ZHENG He-hui, BIAN Zhan-qiang, TIAN Xiang-hong, ZHANG Juan, National
Center for Rural Water Supply Technical Guidance, China ...περισσότερα »
Beim Schilddrüsenkarzinom die richtige Therapie wählen
Welcher Tyrosinkinasehemmer?Welcher der beiden
zugelassenen Tyrosinkinasehemmer ist beim metastasierten medullären
Schilddrüsenkarzinom eher geeignet, den Krankheitsprogress aufzuhalten? Und wie
sollte das Vorgehen beim anaplastischen Karzinom sein?from
#Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader
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Chinese Journal of Clinical Anatomy, Year 2016, Issue 01 -New Issue Alert.
From: order@email.oriprobe.comDate: March 06, 2016
at 08:07AM[image: 1PHav7d]New Issue TOC Alert*Dear Valued Customer*,[image:
1SchPFA] We are pleased to deliver your requested table of contents alert for
*Chinese Journal of Clinical Anatomy*. Year *2016* Issue *01* is now available
on CAOD. *In this issue:* Perforator flap research:a candid view (穿支皮瓣研究的新趋势)MEI
Jin, TANG Mao-lin, XU Da-chuan, Department of Anatomy, Wenzhou Medical College,
Institute of Clinical Anatomy, Southern Medical University…… page:1-3Experts
consensus for clinical application principle of perfora...περισσότερα »
Adverse events of postoperative thoracic epidural analgesia, a retrospective analysis of 7273 cases in a tertiary care teaching hospital.
BACKGROUND: Thoracic epidural analgesia is a well
established technique for postoperative pain relief after major abdominal and
thoracic surgery. Safety remains a major concern because of serious adverse
events including epidural haematoma, abscess and permanent neurological deficit.
OBJECTIVE: The aim of this study was to evaluate the incidence and the long-term
outcome of serious adverse events associated with thoracic epidural analgesia.
DESIGN: Retrospective cohort study. SETTING: The study was conducted at a single
institution, a tertiary care teaching hospital. Data were colle...περισσότερα »
Reply to: postoperative shoulder pain after laparoscopic hysterectomy with deep neuromuscular blockade and low-pressure pneumoperitoneum.
No abstract availablefrom Anaesthesia via ola Kala
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Intraoperative hypotension is associated with myocardial damage in noncardiac surgery: An observational study.
BACKGROUND: Perioperative myocardial damage and
infarction (MI) is associated with increased mortality and other postoperative
complications. OBJECTIVES: To assess the incidence of perioperative myocardial
damage in patients undergoing major elective noncardiac surgery, to elucidate
any association with postoperative MI and mortality and to estimate the impact
of preoperative risk factors and intraoperative hypotension. DESIGN:
Observational cohort study. SETTING: Karolinska University Hospital, Stockholm,
Sweden, from October 2012 to May 2013. PATIENTS: In this single-centre
study,...περισσότερα »
Satisfaction and safety using dexmedetomidine or propofol sedation during endoscopic oesophageal procedures: A randomised controlled trial.
BACKGROUND: Dexmedetomidine possesses anxiolytic
and hypnotic properties without respiratory side-effects, making it
theoretically an ideal sedative agent for endoscopic procedures. OBJECTIVE: We
aimed to compare satisfaction and safety among outpatients receiving sedation
with dexmedetomidine or propofol for endoscopic oesophageal procedures. DESIGN:
A randomised controlled study. SETTING: Endoscopic intervention suite at the
Academic Medical Centre in Amsterdam, Netherlands. PARTICIPANTS: Patients aged
at least 18 years, and American Society of Anesthesiologists' physical status
1...περισσότερα »
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