New test stalks diseases early – Science News for Students
Science News for Students Gotcha! New test stalks diseases early Science News for Students … a powerful new test for detecting disease. It uses a common DNA-copying procedure, called PCR, to screen for antibodies in tiny test-tubes containing small amounts of blood or saliva. … They stick to foreign material, such as germs or cancer… Continue reading Gotcha! New test stalks diseases early – Science News for Students
New York’s chewing tobacco ban shows dipping is yesterday’s pastime – The Guardian (blog)
The Guardian (blog) New York’s chewing tobacco ban shows dipping is yesterday’s pastime The Guardian (blog) Gwynn would eventually say that caused the salivary gland cancer that led to his death in June 2014. Gwynn maintained that the cancer was located where he typically placed a wad of tobacco. Other baseball players have suffered complications… Continue reading New York’s chewing tobacco ban shows dipping is yesterday’s pastime – The Guardian (blog)
A Cancer Survivor Shares 5 Ways To Get Better Health Care – Forbes
Forbes A Cancer Survivor Shares 5 Ways To Get Better Health Care Forbes She’d had that feeling for about six months, but dismissed it as a tonsil stone—a pebble-like growth that forms when food or other particles get stuck near the tonsils. After her efforts to dislodge it failed, she ignored it and went on… Continue reading A Cancer Survivor Shares 5 Ways To Get Better Health Care – Forbes
Cancer management technology of the future needs your opinion: take this quick survey https://t.co/WoyGkmJ4z6 #iManageCancer
Cancer management technology of the future needs your opinion: take this quick survey https://t.co/WoyGkmJ4z6 #iManageCancer from #ORL-AlexandrosSfakianakis via simeraentaxei on Inoreader http://twitter.com/ecancer/status/719845074939600896 via IFTTT
Which breast cancers are associated with CNS metastases? Our latest paper examines the latest phenotype: https://t.co/JZiw2n9oqW
Which breast cancers are associated with CNS metastases? Our latest paper examines the latest phenotype: https://t.co/JZiw2n9oqW from #ORL-AlexandrosSfakianakis via simeraentaxei on Inoreader http://twitter.com/ecancer/status/719843801876008960 via IFTTT
Interested in CLL? Register to join our live expert discussion on the latest treatments. https://t.co/uykLmUdizP https://t.co/ymexoYWwMk
Interested in CLL? Register to join our live expert discussion on the latest treatments. https://t.co/uykLmUdizP https://t.co/ymexoYWwMk from #ORL-AlexandrosSfakianakis via simeraentaxei on Inoreader http://twitter.com/ecancer/status/719831178610634755 via IFTTT
Watch Prof Paul Richardson & Prof Mohamad Mohty discuss highlights of #EBMT16 https://t.co/c3EgCsm5eD @TheEBMT https://t.co/xUpmfRaJYU
Watch Prof Paul Richardson & Prof Mohamad Mohty discuss highlights of #EBMT16 https://t.co/c3EgCsm5eD @TheEBMT https://t.co/xUpmfRaJYU from #ORL-AlexandrosSfakianakis via simeraentaxei on Inoreader http://twitter.com/ecancer/status/719828695951765504 via IFTTT
You’ve heard the hype – choral singing can lead to health benefits for cancer patients! Now read the research here: https://t.co/9GlZgEUVIb
You’ve heard the hype – choral singing can lead to health benefits for cancer patients! Now read the research here: https://t.co/9GlZgEUVIb from #ORL-AlexandrosSfakianakis via simeraentaxei on Inoreader http://twitter.com/ecancer/status/719824921703137280 via IFTTT
L’Istituto Nazionale dei Tumori al Teatro alla Scala di Milano
from #ORL-AlexandrosSfakianakis via simeraentaxei on Inoreader http://ift.tt/1TOCHq0 via IFTTT
IJMS, Vol. 17, Pages 548: Role of Serum Uric Acid and Ferritin in the Development and Progression of NAFLD
Nonalcoholic fatty liver disease (NAFLD), tightly linked to the metabolic syndrome (MS), has emerged as a leading cause of chronic liver disease worldwide. Since it is potentially progressive towards non-alcoholic steatohepatitis (NASH) and hepatic fibrosis, up to cirrhosis and its associated complications, the need for predictive factors of NAFLD and of its advanced forms is… Continue reading IJMS, Vol. 17, Pages 548: Role of Serum Uric Acid and Ferritin in the Development and Progression of NAFLD
Ceftazidime resistance among clinical isolates of Pseudomonas aeruginosa
The elucidation of mechanisms of ceftazidime resistance among clinical isolates of Pseudomonas aeruginosa using genomic data [PublishAheadOfPrint]: Ceftazidime is one of the few cephalosporins with activity against *Pseudomonas aeruginosa*. Using whole genome comparative analysis, we set out to determine the prevalent mechanism(s) of resistance to ceftazidime using a set of 181 clinical isolates. These isolates represented various multi-locus sequence types that consisted of both ceftazidime susceptible and resistant populations. A presumptive resistance mechanism against ceftazid... περισσότερα »
Vancomycin-Susceptible Staphylococcus aureus
Complete Reconstitution of the VISA Phenotype of Mu50 in Vancomycin-Susceptible Staphylococcus aureus [PublishAheadOfPrint]: Complete reconstitution of the vancomycin-intermediate *Staphylococcus aureus* (VISA) phenotype of Mu50 was achieved by sequentially introducing mutations into six genes of a vancomycin-susceptible *S. aureus* (VSSA) strain N315IP. The mutated six genes detected in VISA strain Mu50, but not in N315IP. Introduction of mutation Ser329Leu into *vraS* encoding the sensor histidine kinase of *vraSR* two-component regulatory (TCR) system and another mutation Glu146... περισσότερα »
Oritavancin, Dalbavancin and Vancomycin against Methicillin-Resistant Staphylococcus aureus Isolates
Comparative In vitro Activity of Oritavancin, Dalbavancin and Vancomycin against Methicillin-Resistant Staphylococcus aureus Isolates in a Non-Dividing State [PublishAheadOfPrint]: Antibacterial agents that kill non-dividing bacteria may be of utility in treating persistent infections. Oritavancin and dalbavancin are bactericidal lipoglycopeptides approved for acute bacterial skin and skin structure infections in adults caused by susceptible gram-positive pathogens. Using time-kill methodology, we demonstrate that oritavancin exerts bactericidal activity against methicillin-resista... περισσότερα »
Acute Kidney Injury Among Patients Receiving Concomitant Vancomycin and Piperacillin/tazobactam
Epidemiology of Acute Kidney Injury Among Patients Receiving Concomitant Vancomycin and Piperacillin/tazobactam: Opportunities for Antimicrobial Stewardship [PublishAheadOfPrint]: Background: Despite their common use as empiric combination therapy for the better part of a decade there has been a recent association between combination therapy with vancomycin and piperacillin/tazobactam and high rates of acute kidney injury (AKI). Reasons for this increased association are unclear and this analysis was designed to investigate the association. Methods: Retrospective cohort and case-co...περισσότερα »
Neighbourhood greenness and asthma in preschool children
Associations between neighbourhood greenness and asthma in preschool children in Kaunas, Lithuania: a case-control study: Objectives The aim of this study was to investigate the associations between surrounding greenness levels and asthma among children, and to explore a possible change of this association by the distance of the residence to a city park. Design A nested case–control study. Setting Children aged 4–6 years residing at their current address since birth in Kaunas, Lithuania, whose mothers were recruited in 2007–2009 to the KANC newborns cohort study. Participants T...περισσότερα »
Lung-protective ventilation initiated in the emergency department
(LOV-ED): a study protocol for a quasi-experimental, before-after trial aimed at reducing pulmonary complications: Introduction In critically ill patients, acute respiratory distress syndrome (ARDS) and ventilator-associated conditions (VACs) are associated with increased mortality, survivor morbidity and healthcare resource utilisation. Studies conclusively demonstrate that initial ventilator settings in patients with ARDS, and at risk for it, impact outcome. No studies have been conducted in the emergency department (ED) to determine if lung-protective ventilation in patients at ... περισσότερα »
Near Infrared Image-Guided Lymphatic Mapping of Regional Lymph Nodes in Esophageal Cancer
Safety and Feasibility of To assess safety and feasibility of an intraoperative, minimally invasive NIR image-guided approach to lymphatic mapping in esophageal cancer patients. Although local lymph nodes (LNs) are removed with the esophageal specimen, no techniques are available to identify the regional LNs (separate from the esophagus) during esophagectomy. We hypothesize that NIR imaging can identify regional LNs with potential to improve staging and the extent of lymphadenectomy (LAD).
Tumour thickness as a determinant of nodal metastasis in oral tongue carcinoma
Tumour thickness as a determinant of nodal metastasis in oral tongue carcinoma: Background Tumour thickness is a strong predictor for cervical node involvement in oral cavity squamous cell carcinomas (SCCs), with a recent meta-analysis concluding a 4-mm optimal prognostic cut-off point. No consensus has been reached for the tumour thickness cut-off for oral tongue SCCs. Methods A retrospective review of prospectively collected data from 112 patients by the Northern Sydney Cancer Centre (Australia) with primary oral tongue SCC was conducted. Tumour thickness was measured by standard ...περισσότερα »
Flexible hand-held laser fibers in microsurgical removal of acoustic neuromas (vestibular schwannomas)
Safety and usefulness of via Clinical Neurology and Neurosurgery Publication date: June 2016 *Source:*Clinical Neurology and Neurosurgery, Volume 145 Author(s): Luciano Mastronardi, Guglielmo Cacciotti, Ettore Di Scipio, Giuseppe Parziale, Raffaelino Roperto, Maria Pia Tonelli, Ettore Carpineta AimsWe performed a retrospective non-randomized study to analyze the results of microsurgery of acoustic neuromas (AN) using two different flexible hand-held laser fibers, CO2 (Omniguide®) and 2μ-Thulium (Revolix jr ®).MethodsFrom September 2010 to June 2015, 84 patients suffering from AN have ...περισσότερα »
Traumatic Brain Injury and Subarachnoid Hemorrhage : Early CSF and Serum S100B Concentrations for Outcome Prediction
Early CSF and Serum S100B Concentrations for Outcome Prediction in via Clinical Neurology and Neurosurgery Publication date: Available online 8 April 2016 *Source:*Clinical Neurology and Neurosurgery Author(s): Isabel Kellermann, Andrea Kleindienst, Nirjhar Hore, Michael Buchfelder, Sebastian Brandner ObjectivesS100B has been proposed as a putative biochemical marker in determining the extent of brain injury and corresponding prognosis in neurotrauma. The aim of this study was to evaluate the prognostic value of S100B early concentrations in serum and cerebrospinal fluid (CSF) in tra...περισσότερα »
Follow-up issues in children with mild traumatic brain injuries
Follow-up issues in children with mild traumatic brain injuries: Journal of Neurosurgery: Pediatrics, Ahead of Print. OBJECTIVE Concerns about mild traumatic brain injury (mTBI) have increased in recent years, and neurosurgical consultation is often requested for patients with radiographic abnormalities or clinical findings suspicious for mTBI. However, to the authors' knowledge, no study has used the Acute Concussion Evaluation (ACE) tool to systematically evaluate the evolution of symptoms in patients with mTBI during neurosurgical follow-up. The goal in this study was to evaluat...περισσότερα »
Effect of molding helmets on intracranial pressure and head shape in nonsurgically treated sagittal craniosynostosis patients
Effect of molding helmets on intracranial pressure and head shape in nonsurgically treated sagittal craniosynostosis patients: Journal of Neurosurgery: Pediatrics, Ahead of Print. OBJECTIVE Cranial vault expansion is performed in pediatric patients with craniosynostosis to improve head shape. Another argument for performing total cranial vault reconstruction is the potential reduction in the harmful effects of elevated intracranial pressure (ICP) that are associated with craniosynostosis. Alternatively, molding helmets have been shown to improve the cranial index (CI) in patients w...περισσότερα »
The 11th cranial nerve (CN XI, or accessory nerve) is described as having a cranial and a spinal root, the latter arising from the upper segments of the spinal cord through a number of very fine rootlets
Functional anatomy of the accessory nerve studied through intraoperative electrophysiological mapping: Journal of Neurosurgery, Ahead of Print. OBJECTIVE Classically the 11th cranial nerve (CN XI, or accessory nerve) is described as having a cranial and a spinal root, the latter arising from the upper segments of the spinal cord through a number of very fine rootlets. According to classical knowledge, the cranial root gives motor innervation to the vocal cords, whereas the spinal root provides the motor innervation of the sternocleidomastoid muscle (SCM) and of the upper portions o... περισσότερα »
Chronic frontal hemodynamic disturbances are associated with executive dysfunction in adult patients with moyamoya disease (MMD)
Postoperative executive function in adult moyamoya disease: a preliminary study of its functional anatomy and behavioral correlates: Journal of Neurosurgery, Ahead of Print. OBJECTIVE Chronic frontal hemodynamic disturbances are associated with executive dysfunction in adult patients with moyamoya disease (MMD). However, the impact of surgical revascularization on executive dysfunction and its underlying mechanism remains unclear. The aim of the present study was to examine the postoperative radiological correlates of cognitive improvement and thereby explore its underlying mechani...περισσότερα »
Stereotactic radiosurgery for the treatment of cerebral arteriovenous malformations
Seizure outcomes after OBJECTIVE Patients with cerebral arteriovenous malformations (AVMs) commonly present with seizure. Seizure outcomes in patients treated with stereotactic radiosurgery (SRS) are poorly defined. A case series of patients with cerebral AVMs treated with SRS is presented to evaluate long-term seizure outcome. METHODS A retrospective review of the medical record was performed, identifying 204 consecutive patients with AVMs treated with SRS between January 1991 and June 2012. Clinical and radiographic data were evaluated. Seizure outcome was measured using the E... περισσότερα »
Arteriovenous malformation grading scales in predicting outcomes after stereotactic radiosurgery
Comparative analysis of OBJECTIVE Successful stereotactic radiosurgery (SRS) for the treatment of arteriovenous malformations (AVMs) results in nidus obliteration without new neurological deficits related to either intracranial hemorrhage (ICH) or radiation-induced complications (RICs). In this study the authors compared 5 AVM grading scales (Spetzler-Martin grading scale, radiosurgery-based AVM score [RBAS], Heidelberg score, Virginia Radiosurgery AVM Scale [VRAS], and proton radiosurgery AVM scale [PRAS]) at predicting outcomes after SRS. METHODS The study group consisted of 38...περισσότερα »
Antitumor effect of CXCR4 antagonist AMD3100 on the tumorigenic cell line of BHP10-3 papillary thyroid cancer cells.
*Antitumor effect of CXCR4 antagonist AMD3100 on the tumorigenic cell line of BHP10-3 papillary thyroid cancer cells.* Head Neck. 2016 Apr 7; Authors: Jung YH, Lee DY, Cha W, Kim BH, Sung MW, Kim KH, Ahn SH Abstract BACKGROUND: A tumorigenic cell line (BHP10-3M) derived from nontumorigenic papillary thyroid carcinoma (PTC) cells (BHP10-3) having rearranged during transfection (RET)/PTC1 gene rearrangement might have a higher expression of CXCR4, either quantitatively or functionally. The authors also postulated that CXCR4-mediated invasion or tumorigenesis could be blocked by CXC... περισσότερα »
Prognostic role of the Bethesda System for conventional papillary thyroid carcinoma.
*Prognostic role of the Bethesda System for conventional papillary thyroid carcinoma.* Head Neck. 2016 Apr 7; Authors: Gweon HM, Koo HR, Son EJ, Kim JA, Youk JH, Hong SW, Lim BJ Abstract BACKGROUND: The purpose of this study was to investigate the role of the Bethesda System for Reporting Thyroid Cytopathology (BSRTC) as a prognostic marker in conventional papillary thyroid carcinoma (PTC). METHODS: A total of 397 patients who underwent ultrasound-guided fine-needle aspiration biopsy (FNAB) and surgery for conventional PTCs were enrolled. The association between the Bethesda categ... περισσότερα »
Clinical outcomes of patients with hypercalcitoninemia after initial treatment for medullary thyroid cancer and postoperative serum calcitonin cutoffs for predicting structural recurrence.
*Clinical outcomes of patients with hypercalcitoninemia after initial treatment for medullary thyroid cancer and postoperative serum calcitonin cutoffs for predicting structural recurrence.* Head Neck. 2016 Apr 7; Authors: Cho YY, Jang HW, Jang JY, Kim TH, Choe JH, Kim JH, Kim JS, Kim SW, Chung JH Abstract BACKGROUND: Persistent hypercalcitoninemia is reported in 40% to 60% of patients with medullary thyroid cancer (MTC) after initial therapy, but their clinical outcomes have not been clearly studied. We evaluated the outcomes of MTC with hypercalcitoninemia and assessed the cuto...περισσότερα »
A Phase 2 Randomised Controlled Trial of Nicotinamide for Skin Cancer Chemoprevention in Renal Transplant Recipients.
Alexandros G. SfakianakisστοHead,Neck,Brain,Cervical Spine and Esophageal Cancers by Alexandros G. SfakianakisΠριν από 13 δευτερόλεπτα
*A Phase 2 Randomised Controlled Trial of Nicotinamide for Skin Cancer Chemoprevention in Renal Transplant Recipients.* Br J Dermatol. 2016 Apr 8; Authors: Chen AC, Martin AJ, Dalziell RA, McKenzie CA, Lowe PM, Eris JM, Scolyer RA, Dhillon HM, Vardy JL, Bielski VA, Halliday GM, Damian DL Abstract BACKGROUND: Immunosuppressed transplant recipients have an 80-fold increased risk of cutaneous squamous cell carcinoma (SCC) and a 16-fold increased risk of basal cell carcinoma (BCC). Nicotinamide (vitamin B3) reduces the incidence of non-melanoma skin cancer (NMSC) in immune competent ... περισσότερα »
Anti-PD-1 therapy in nonmelanoma skin cancer.
Alexandros G. SfakianakisστοHead,Neck,Brain,Cervical Spine and Esophageal Cancers by Alexandros G. SfakianakisΠριν από 13 δευτερόλεπτα
*Anti-PD-1 therapy in nonmelanoma skin cancer.* Br J Dermatol. 2016 Apr 8; Authors: Winkler JK, Schneiderbauer R, Bender C, Sedlaczek O, Fröhling S, Penzel R, Enk A, Hassel JC Abstract BACKGROUND: Treatment options for advanced nonmelanoma skin cancers (NMSCs) are still limited. In various tumour entities, including melanoma, immune checkpoint inhibition with antibodies targeting programmed cell death-1 (PD-1) has recently demonstrated promising results. OBSERVATIONS: We report on two patients with NMSCs who received the anti-PD-1 antibody pembrolizumab. The first patient received... περισσότερα »
Meningioma consistency prediction utilizing tumor to cerebellar peduncle intensity on T2-weighted magnetic resonance imaging sequences: TCTI ratio
TCTI ratio: Journal of Neurosurgery, Ahead of Print. OBJECTIVE Meningioma consistency, firmness or softness as it relates to resectability, affects the difficulty of surgery and, to some degree, the extent of resection. Preoperative knowledge of tumor consistency would affect preoperative planning and instrumentation. Several methods of prediction have been proposed, but the majority lack objectivity and reproducibility or generalizability to other surgeons. In a previous pilot study of 20 patients the authors proposed a new method of prediction based on tumor/cerebellar peduncle T... περισσότερα »
Quality of life is maintained using Gamma Knife radiosurgery
a prospective study of a brain metastases patient cohort: Journal of Neurosurgery, Ahead of Print. OBJECTIVE Gamma Knife radiosurgery (GKRS) is increasingly used in the management of brain metastases (BMs), but few studies have evaluated how GKRS impacts quality of life (QOL). The aim of this study was to monitor QOL as the primary end point following GKRS in a patient cohort with BM. METHODS The study included 97 consecutive patients with 1–6 BMs treated with GKRS between May 2010 and September 2011. QOL was assessed at baseline and at 1, 3, 6, 9, and 12 months postoperatively usi... περισσότερα »
Financial burden associated with the residency match in neurological surgery
Financial burden associated with the residency match in neurological surgery: Journal of Neurosurgery, Ahead of Print. OBJECTIVE Application for a residency position in neurosurgery is a highly competitive process. Visiting subinternships and interviews are integral parts of the application process that provide applicants and programs with important information, often influencing rank list decisions. However, the process is an expensive one that places significant financial burden on applicants. In this study, the authors aimed to quantify expenses incurred by 1st-year neurosurgery... περισσότερα »
Endoscopic endonasal control of the paraclival internal carotid artery by Fogarty balloon catheter inflation
an anatomical study: Journal of Neurosurgery, Ahead of Print. OBJECTIVE Neurosurgical management of many vascular and neoplastic lesions necessitates control of the internal carotid artery (ICA). The aim of this study was to investigate the feasibility of achieving control of the ICA through the endoscopic endonasal approach by temporary occlusion with a Fogarty balloon catheter. METHODS Ten endoscopic endonasal paraseptal approaches were performed on cadaveric specimens. A Fogarty balloon catheter was inserted through a sellar bony opening and pushed laterally and posteriorly ext... περισσότερα »
Intramedullary spinal cord spindle cell hemangioma
Intramedullary spindle cell hemangioma: case report: Journal of Neurosurgery: Spine, Ahead of Print. The authors describe the case of a 48-year-old man found to have the first reported intramedullary spinal cord spindle cell hemangioma. Previous research indicates that spindle cell hemangiomas are rarely found in the spine. Only 3 previous cases exist, all in the intradural, extramedullary space. In the present case, gross-total resection of the tumor was possible with no loss of function from baseline. This report presents the successful resection of the first reported intramedull... περισσότερα »
A comparison of the endoscopic and laparoscopic view of the gastroesophageal junction in the use of transoral fundoplication.
[image: http:--linkinghub.elsevier.com-ihub-imag] Related Articles *A comparison of the endoscopic and laparoscopic view of the gastroesophageal junction in the use of transoral fundoplication.* Am J Surg. 2015 Dec;210(6):1018-22; discussion 1022-3 Authors: Ihde GM, Dill LA, Lister DG, Lucchese CF, Cottrell C, Krone PK, Stone RA Abstract BACKGROUND: Endoscopic fundoplication requires accurate evaluation of the gastroesophageal junction (GJ) to determine if hiatal hernia repair is necessary before fundoplication. We compared the endoscopic and laparoscopic evaluations of the GJ. M... περισσότερα »
Incidence of gastroesophageal reflux disease (GERD), active component, U.S. Armed Forces, 2005-2014.
Related Articles *Incidence of gastroesophageal reflux disease (GERD), active component, U.S. Armed Forces, 2005-2014.* MSMR. 2015 Jul;22(7):14-7 Authors: Daniele DO, Oh GT, O'Donnell FL, Clark LL Abstract Gastroesophageal reflux disease (GERD) is a common condition among adults that can cause symptoms such as frequent heartburn, substernal chest pain, and regurgitation of food. During 2005-2014, a total of 137,081 active component service members had an incident (first-ever) diagnosis of GERD (incidence rate: 101.3 per 10,000 person-years). Incidence rates were higher than thei... περισσότερα »
Neonatal acute lymphocytic leukaemia: an unusual presentation of a rare disease.
[image: http:--highwire.stanford.edu-icons-exter] Related Articles *Neonatal acute lymphocytic leukaemia: an unusual presentation of a rare disease.* BMJ Case Rep. 2015;2015 Authors: Palman J, Karam M, Chee Y, Kandala V Abstract Infantile acute lymphocytic leukaemia (ALL) seldom presents within the first month of life. Most are diagnosed before birth. Postnatal diagnoses are easily recognisable when characteristic features are present, namely hepatosplenomegaly, leukaemia cutis or infiltrative disease of the extramedullar and central nervous system. However, some children present...περισσότερα »
Esophageal subepithelial lesion diagnosed as malignant gastrointestinal neuroectodermal tumor.
[image: http:--http://ift.tt/1YyhL4R] [image: http:--http://ift.tt/1Fkw4zC] Related Articles *Esophageal subepithelial lesion diagnosed as malignant gastrointestinal neuroectodermal tumor.* World J Gastroenterol. 2015 May 14;21(18):5739-43 Authors: Kim SB, Lee SH, Gu MJ Abstract A 21-year-old male visited our hospital with a complaint of aggravating dysphagia and odynophagia for a few days. Esophagogastroduodenoscopy showed huge bulging mucosa with an intact surface causing luminal narrowing at 35 cm from the incisor teeth. Endoscopic ultrasonography showed an about 35 mm sized ... περισσότερα »
Effect of peroral esophageal myotomy for achalasia treatment: A Chinese study.
[image: http:--http://ift.tt/1YyhL4R] [image: http:--http://ift.tt/1Fkw4zC] Related Articles *Effect of peroral esophageal myotomy for achalasia treatment: A Chinese study.* World J Gastroenterol. 2015 May 14;21(18):5622-9 Authors: Lu B, Li M, Hu Y, Xu Y, Zhang S, Cai LJ Abstract AIM: To assess the safety and feasibility of peroral esophageal myotomy (POEM) in patients with achalasia. METHODS: From January 2012 to March 2014, 50 patients (28 men, 22 women; mean age: 42.8 years, range: 14-70 years) underwent POEM. Pre- and postoperative symptoms were quantified using the Eckardt s... περισσότερα »
Shorter myotomy on the gastric site (≤2.5 cm) provides adequate relief of dysphagia in achalasia patients.
[image: http:--media.wiley.com-assets-7315-19-Wi] Related Articles *Shorter myotomy on the gastric site (≤2.5 cm) provides adequate relief of dysphagia in achalasia patients.* Dis Esophagus. 2015 Jul;28(5):412-7 Authors: Salvador R, Caruso V, Costantini M, Parise P, Nicoletti L, Cavallin F, Zanatta L, Bardini R, Ancona E, Zaninotto G Abstract The right length of the myotomy on the gastric side for esophageal achalasia is still a debated issue. We aimed to investigate the final outcome after classic myotomy (CM) as compared with a longer myotomy on the gastric side (LM) in two coh... περισσότερα »
Cervical Paraganglioma Mimicking Thyroid Nodule: A Rare Clinical Case.
*Cervical Paraganglioma Mimicking Thyroid Nodule: A Rare Clinical Case.* Case Rep Endocrinol. 2016;2016:8527279 Authors: Aydoğan Bİ, Dizbay Sak S, Güllü S Abstract Objective. Paraganglioma is a rare neuroendocrine tumor. When it is located in the neck, it is commonly misdiagnosed as other thyroid neoplasms. Case Report. We report a case of cervical paraganglioma in a 55-year-old female. Patient was admitted to our clinic with goiter and neck pain. Thyroid ultrasonography revealed a 20 mm solitary, heterogeneous nodule located in the upper pole of left thyroid lobe. Fine needle asp...περισσότερα »
Isolated Metastasis in Male Breast from Differentiated Thyroid Carcinoma - Oncological Curiosity. A Case Report and Review of Literature.
*Isolated Metastasis in Male Breast from Differentiated Thyroid Carcinoma - Oncological Curiosity. A Case Report and Review of Literature.* Indian J Surg Oncol. 2016 Mar;7(1):91-94 Authors: Parasuraman L, Kane SV, Pai PS, Shanghvi K Abstract Papillary carcinomas are the most common thyroid malignancy accounting for approximately 80 % of thyroid cancers (Rosenbaum and McHenry Expert Rev Anticancer Ther 9:317-329, 2009). They generally manifest as solitary nodules in the thyroid with or without cervical lymphadenopathy. Distant metastases though rare, are commonly seen in lungs and ... περισσότερα »
MicroRNA-1280 modulates cell growth and invasion of thyroid carcinoma through targeting estrogen receptor α.
*MicroRNA-1280 modulates cell growth and invasion of thyroid carcinoma through targeting estrogen receptor α.* Cell Mol Biol (Noisy-le-grand). 2016;62(3):1-6 Authors: Meng D, Li Z, Ma X, Fu L, Qin G Abstract Thyroid cancer (TC) is one of the most common endocrine malignancies, with a steadily increasing incidence and lethality over the last several decades. ERα is a nuclear hormone receptor that has a key role in different cellular process and participates in the development and progression of thyroid cancer. ERα is the predicted target gene of microRNA-1280 (miR-1280). The prese... περισσότερα »
Effectiveness of chemotherapy in advanced differentiated thyroid cancer: a systematic review.
*Effectiveness of chemotherapy in advanced differentiated thyroid cancer: a systematic review.* Endocr Relat Cancer. 2016 Feb;23(2):R71-84 Authors: Albero A, Lopéz JE, Torres A, de la Cruz L, Martín T Abstract In differentiated thyroid carcinoma refractory to radioactive iodine (CDT-RTI), chemotherapy has been considered for decades to be the only systemic therapy with palliative purpose. Phase II studies assessing the efficacy of different chemotherapy outlines have been published. Nevertheless, phase III studies in these tumours have not been performed. Our objective is to eval... περισσότερα »
Incidence of Permanent Hypocalcaemia after Total Thyroidectomy with or without Central Neck Dissection for Thyroid Carcinoma: A Nationwide Claim Study.
*Incidence of Permanent Hypocalcaemia after Total Thyroidectomy with or without Central Neck Dissection for Thyroid Carcinoma: A Nationwide Claim Study.* Clin Endocrinol (Oxf). 2016 Apr 11; Authors: Seo GH, Chai YJ, Choi HJ, Lee KE Abstract OBJECTIVE: Permanent hypocalcaemia is the most common and serious complication after total thyroidectomy (TT). This study examined the impact of central neck dissection (CND) and institutional volume on rates of permanent hypocalcaemia by analysing data held in the nationwide claim database of South Korea. DESIGN: Data from patients who underw... περισσότερα »
Extent of lymph node dissection in papillary thyroid cancer.
*Extent of lymph node dissection in papillary thyroid cancer.* Surgery. 2016 Apr 7; Authors: Sindoni A, Fama' F PMID: 27063342 [PubMed - as supplied by publisher] from pubmed: thyroid cancer http://ift.tt/1SKUsla via IFTTT
Post-adjuvant chemotherapy for triple-negative breast cancer.
*Post-adjuvant chemotherapy for triple-negative breast cancer.* Med Hypotheses. 2016 May;90:74-5 Authors: Sun S, Zhao Y, Xu K PMID: 27063090 [PubMed - in process] from pubmed: thyroid cancer http://ift.tt/1VlatoD via IFTTT
Microrna-199a-5p Functions as a Tumor Suppressor via Suppressing Connective Tissue Growth Factor (CTGF) in Follicular Thyroid Carcinoma.
*Microrna-199a-5p Functions as a Tumor Suppressor via Suppressing Connective Tissue Growth Factor (CTGF) in Follicular Thyroid Carcinoma.* Med Sci Monit. 2016;22:1210-2117 Authors: Sun D, Han S, Liu C, Zhou R, Sun W, Zhang Z, Qu J Abstract BACKGROUND The objective of this study was to explore the role of miR-199a-5p in the development of thyroid cancer, including its anti-proliferation effect and downstream signaling pathway. MATERIAL AND METHODS We conducted qRT-PCR analysis to detect the expressions of several microRNAs in 42 follicular thyroid carcinoma patients and 42 controls... περισσότερα »
Clinical outcomes of patients with hypercalcitoninemia after initial treatment for medullary thyroid cancer and postoperative serum calcitonin cutoffs for predicting structural recurrence.
*Clinical outcomes of patients with hypercalcitoninemia after initial treatment for medullary thyroid cancer and postoperative serum calcitonin cutoffs for predicting structural recurrence.* Head Neck. 2016 Apr 7; Authors: Cho YY, Jang HW, Jang JY, Kim TH, Choe JH, Kim JH, Kim JS, Kim SW, Chung JH Abstract BACKGROUND: Persistent hypercalcitoninemia is reported in 40% to 60% of patients with medullary thyroid cancer (MTC) after initial therapy, but their clinical outcomes have not been clearly studied. We evaluated the outcomes of MTC with hypercalcitoninemia and assessed the cuto...περισσότερα »
Polymorphisms within base and nucleotide excision repair pathways and risk of differentiated thyroid carcinoma.
*Polymorphisms within base and nucleotide excision repair pathways and risk of differentiated thyroid carcinoma.* DNA Repair (Amst). 2016 Mar 31;41:27-31 Authors: Cipollini M, Figlioli G, Maccari G, Garritano S, De Santi C, Melaiu O, Barone E, Bambi F, Ermini S, Pellegrini G, Cristaudo A, Foddis R, Bonotti A, Romei C, Vivaldi A, Agate L, Molinari E, Barale R, Forsti A, Hemminki K, Elisei R, Gemignani F, Landi S Abstract The thyrocytes are exposed to high levels of oxidative stress which could induce DNA damages. Base excision repair (BER) is one of the principal mechanisms of def...περισσότερα »
Antitumor effect of CXCR4 antagonist AMD3100 on the tumorigenic cell line of BHP10-3 papillary thyroid cancer cells.
*Antitumor effect of CXCR4 antagonist AMD3100 on the tumorigenic cell line of BHP10-3 papillary thyroid cancer cells.* Head Neck. 2016 Apr 7; Authors: Jung YH, Lee DY, Cha W, Kim BH, Sung MW, Kim KH, Ahn SH Abstract BACKGROUND: A tumorigenic cell line (BHP10-3M) derived from nontumorigenic papillary thyroid carcinoma (PTC) cells (BHP10-3) having rearranged during transfection (RET)/PTC1 gene rearrangement might have a higher expression of CXCR4, either quantitatively or functionally. The authors also postulated that CXCR4-mediated invasion or tumorigenesis could be blocked by CXC... περισσότερα »
Expression of sodium iodide symporter in human breast tissues.
*Expression of sodium iodide symporter in human breast tissues.* J BUON. 2016 Jan-Mar;21(1):53-60 Authors: Angelousi A, Nonni A, Kassi E, Kontzoglou K Abstract PURPOSE: Sodium iodide symporter (NIS) expression in breast cancer (BC) tissues suggests the possibility of using radioiodine for diagnostic and therapeutic purposes. This study evaluated NIS protein expression in primary BC samples and its association with BC prognostic markers and thyroid functional parameters. METHODS: Fifty-six breast tissue samples from 52 operated women (41 BC, 11 benign breast diseases (BBD) and 4 pe... περισσότερα »
Cytotechnologist Performance for Screening Hürthle Cell Atypia in Indeterminate Thyroid Fine-Needle Aspirates.
Related Articles *Cytotechnologist Performance for Screening Hürthle Cell Atypia in Indeterminate Thyroid Fine-Needle Aspirates.* Acta Cytol. 2015;59(5):377-83 Authors: VandenBussche CJ, Adams C, Ali SZ, Olson MT Abstract OBJECTIVES: We have previously shown that specimens diagnosed as containing Hürthle cells have a 12% chance of being malignant if they are classified as atypia of undetermined significance (AUS-HC). The identification of Hürthle cells by cytotechnologists (CTs) during screening can improve cytopathologist efficiency and may prevent diagnostic errors due to the ... περισσότερα »
Cytologic Features and Immunocytochemical Profiles of Malignant Effusions with Metastatic Papillary Thyroid Carcinoma: A Case Series from a Single Institution.
Related Articles *Cytologic Features and Immunocytochemical Profiles of Malignant Effusions with Metastatic Papillary Thyroid Carcinoma: A Case Series from a Single Institution.* Acta Cytol. 2015;59(5):412-7 Authors: Lew M, Pang JC, Roh MH, Jing X Abstract OBJECTIVE: Malignant effusions due to papillary thyroid carcinoma (PTC) are rare, but portend a poor prognosis. PTC metastases, although rare, most frequently occur in the lungs and bone. Therefore, differentiating thyroid etiology of malignant effusions from other sites becomes clinically significant in patient management. Th... περισσότερα »
Significance of Subcategory Atypia of Undetermined Significance/Follicular Lesion of Undetermined Significance Showing Both Cytologic and Architectural Atypia in Thyroid Aspiration Cytology.
Related Articles *Significance of Subcategory Atypia of Undetermined Significance/Follicular Lesion of Undetermined Significance Showing Both Cytologic and Architectural Atypia in Thyroid Aspiration Cytology.* Acta Cytol. 2015;59(5):370-6 Authors: Jung YY, Jung S, Lee HW, Oh YL Abstract OBJECTIVE: The Bethesda System for Reporting Thyroid Cytopathology is now widely used as the standard reporting system for fine-needle aspiration cytology (FNAC). Recently, several studies have attempted to subcategorize the atypia of undetermined significance (AUS)/follicular lesion of undetermi... περισσότερα »
Identification of occult tumors by whole-specimen mapping in solitary papillary thyroid carcinoma.
Related Articles *Identification of occult tumors by whole-specimen mapping in solitary papillary thyroid carcinoma.* Endocr Relat Cancer. 2015 Aug;22(4):679-86 Authors: Park SY, Jung YS, Ryu CH, Lee CY, Lee YJ, Lee EK, Kim SK, Kim TS, Kim TH, Jang J, Park D, Dong SM, Kang JG, Lee JS, Ryu J Abstract We undertook this study to estimate an accurate incidence and spread patterns of occult papillary thyroid carcinoma (PTC) in patients with a preoperative diagnosis of solitary PTC by using whole-specimen mapping of all specimens after a total thyroidectomy. Enrolled prospectively in t... περισσότερα »
Primary acute stroke thrombectomy
within 3 h for large artery occlusion (PAST3-LAO): a pilot study: Background and purpose In recent trials, acute ischemic stroke (AIS) from large artery occlusion (LAO) was resistant to intravenous thrombolysis and adjunctive stent retriever thrombectomy (SRT) was associated with better perfusion and outcomes. Despite benefit, 39–68% of patients had poor outcomes. Thrombectomy in AIS with LAO within 3 h is performed secondary to intravenous thrombolysis, which may be associated with delay. The purpose of our study is to evaluate the safety, feasibility, recanalization rate, and ou...περισσότερα »
Microendoscopic Removal of Deep-Seated Brain Tumors Using Tubular Retraction System
Microendoscopic Removal of Deep-Seated Brain Tumors Using Tubular Retraction System: J Neurol Surg A Cent Eur Neurosurg DOI: 10.1055/s-0036-1580595 Background Retraction of the overlying brain can be difficult without causing significant trauma when using traditional brain retractors with blades. These retractors may produce focal pressure and may result in brain contusion or infarction. Tubular retractors offer the advantage of low retracting pressure that is less likely to be traumatic. Low retraction pressure in the tubular retractor is due to the distribution of retraction for... περισσότερα »
Atrial Fibrillation Attributed to Local Anesthesia With Epinephrine for Mohs Micrographic Surgery.
Atrial Fibrillation Attributed to Local Anesthesia With Epinephrine for Mohs Micrographic Surgery.: No abstract available
Rapid Lump Examination as a New Aid to Speedup Mohs Micrographic Surgery
A Pilot Study.: BACKGROUND: Although most cases of basal cell carcinoma (BCC) are curable, facial and recurrent BCCs require time consuming and labor-intensive Mohs micrographic surgery (MMS) to ensure complete removal with optimal cosmetic results. To handle the skin cancer epidemic, there is an urgent need to speedup MMS. Recently, rapid lump examination (RLE) has been shown to enable quick histologic examination, but its usefulness within MMS is unknown. OBJECTIVE: To evaluate the accuracy of RLE for the detection of residual BCC during MMS. MATERIALS AND METHODS: Twenty-two BCC... περισσότερα »
Percutaneous Treatments of Trigeminal Neuralgia
Comparing Percutaneous Treatments of Trigeminal Neuralgia: 19 Years of Experience in a Single Centre: *Background:* Glycerol rhizolysis, thermocoagulation, and balloon compression are well established in the treatment of trigeminal neuralgia. *Objective:* To compare the outcome profile of these 3 percutaneous procedures in a single centre over a long follow-up period. *Methods:* Over 19 years, 393 procedures were performed on 210 trigeminal neuralgia patients. Patient records and telephone follow-up were used to determine demographic and operative details and surgical outcomes. The ...περισσότερα »
Doxorubicin is a well-known cause of toxic erythema of chemotherapy
Flagellate Pattern of Toxic Erythema of Chemotherapy Due to Doxorubicin: A Case Report: Background: Doxorubicin is an antineoplastic agent frequently used in diverse cancer regimens. Cutaneous adverse effects have frequently been reported with its use. However, a flagellate-like dermatitis is not mentioned in the literature. Objective: The investigators report a case of toxic erythema of chemotherapy with a flagellate pattern induced by doxorubicin. Methods and Results: A 75-year-old woman with endometrial cancer received doxorubicin as part of her treatment. After her third cycl... περισσότερα »
The challenges of implementing electronic health records for anesthesia use outside the operating room.
The challenges of implementing electronic health records for anesthesia use outside the operating room.: Purpose of review: The nonoperating room environment presents a number of distinct challenges for anesthesiologists in the implementation of electronic health records (EHRs). These include documentation compliance, billing, and room design. Recent findings: EHRs offer multiple opportunities for improved continuity of care, expedited preoperative evaluation, and seamless transitions between anesthesia and nonanesthesia providers. Additionally, data gathered through adoption of EHR... περισσότερα »
Effect of baclofen on the acid pocket at the gastroesophageal junction.
[image: http:--media.wiley.com-assets-7315-19-Wi] Related Articles *Effect of baclofen on the acid pocket at the gastroesophageal junction.* Dis Esophagus. 2015 Jul;28(5):488-95 Authors: Scarpellini E, Boecxstaens V, Farré R, Bisschops R, Dewulf D, Gasbarrini A, Pauwels A, Blondeau K, Tack J Abstract Previous studies established that a pocket of highly acidic gastric juice is present postprandially at the gastroesophageal junction in man. The GABA-B agonist baclofen inhibits postprandial reflux events through its effects on the lower esophageal sphincter (LES). The aim of the curr... περισσότερα »
Topical mitomycin C can effectively alleviate dysphagia in children with long-segment caustic esophageal strictures.
[image: http:--media.wiley.com-assets-7315-19-Wi] Related Articles *Topical mitomycin C can effectively alleviate dysphagia in children with long-segment caustic esophageal strictures.* Dis Esophagus. 2015 Jul;28(5):422-7 Authors: El-Asmar KM, Hassan MA, Abdelkader HM, Hamza AF Abstract Caustic ingestion in children and the resulting long esophageal strictures are usually difficult to be managed, and eventually, esophageal replacement was required for cases refractory to frequent dilatation sessions. Topical mitomycin C (MMC) application has been used recently to improve the resul... περισσότερα »
Diabetes mellitus is an independent risk for gastroesophageal reflux disease among urban African Americans.
[image: http:--media.wiley.com-assets-7315-19-Wi] Related Articles *Diabetes mellitus is an independent risk for gastroesophageal reflux disease among urban African Americans.* Dis Esophagus. 2015 Jul;28(5):405-11 Authors: Natalini J, Palit A, Sankineni A, Friedenberg FK Abstract An association between gastroesophageal reflux disease (GERD) and diabetes mellitus (DM) has been reported. Studies have not been population-based and have failed to include a representative sample of African American subjects. The aim of the study was to determine if DM is independently associated with ... περισσότερα »
Phenotypic and molecular analyses of primary lateral sclerosis.
*Phenotypic and molecular analyses of primary lateral sclerosis.* Neurol Genet. 2015 Jun;1(1):e3 Authors: Mitsumoto H, Nagy PL, Gennings C, Murphy J, Andrews H, Goetz R, Floeter MK, Hupf J, Singleton J, Barohn RJ, Nations S, Shoesmith C, Kasarskis E, Factor-Litvak P Abstract OBJECTIVE: To understand phenotypic and molecular characteristics of patients with clinically "definite" primary lateral sclerosis (PLS) in a prospective study. METHODS: Six sites enrolled 41 patients who had pure upper motor neuron dysfunction, bulbar symptoms, a normal EMG done within 12 months of enrollmen...περισσότερα »
Esophageal Stricture Secondary to Candidiasis in a Child with Glycogen Storage Disease 1b.
*Esophageal Stricture Secondary to Candidiasis in a Child with Glycogen Storage Disease 1b.* Pediatr Gastroenterol Hepatol Nutr. 2016 Mar;19(1):71-75 Authors: Lee KJ, Choi SJ, Kim WS, Park SS, Moon JS, Ko JS Abstract Esophageal candidiasis is commonly seen in immunocompromised patients; however, candida esophagitis induced stricture is a very rare complication. We report the first case of esophageal stricture secondary to candidiasis in a glycogen storage disease (GSD) 1b child. The patient was diagnosed with GSD type 1b by liver biopsy. No mutation was found in the G6PC gene, bu... περισσότερα »
Foramen magnum meningioma: The midline suboccipital subtonsillar approach.
*Foramen magnum meningioma: The midline suboccipital subtonsillar approach.* Clin Neurol Neurosurg. 2016 Apr 2;145:28-34 Authors: Dobrowolski S, Ebner F, Lepski G, Tatagiba M Abstract OBJECTIVES: Foramen magnum meningiomas (FMMs) represent a technical challenge even for experienced neurosurgeons, because they grow in close contact with osteoarticular, nervous, and vascular structures that cannot be sacrificed or retracted during surgery. Our goal is to present our experience with 24 cases of surgically resected foramen magnum meningiomas used the midline suboccipital subtonsillar ... περισσότερα »
Why do clinicians choose the therapies and techniques they do? Exploring clinical decision-making via treatment selections in dysphagia practice.
*Why do clinicians choose the therapies and techniques they do? Exploring clinical decision-making via treatment selections in dysphagia practice.* Int J Speech Lang Pathol. 2016 Apr 7;:1-8 Authors: McCurtin A, Healy C Abstract PURPOSE: Speech-language pathologists (SLPs) are assumed to use evidence-based practice to inform treatment decisions. However, the reasoning underpinning treatment selections is not well known. Understanding why SLPs choose the treatments they do may be clarified by exploring the reasoning tied to specific treatments such as dysphagia interventions. METHO... περισσότερα »
Viscosity of thickened fluids that relate to the Australian National Standards.
*Viscosity of thickened fluids that relate to the Australian National Standards.* Int J Speech Lang Pathol. 2015 Oct 1;:1-9 Authors: Karsten Hadde E, Ann Yvette Cichero J, Michael Nicholson T Abstract PURPOSE: In 2007, Australia published standardized terminology and definitions for three levels of thickened fluids used in the management of dysphagia. This study examined the thickness of the current Australian National Fluid Standards rheologically (i.e. viscosity, yield stress) and correlated these results with the "fork test", as described in the national standards. METHOD: Cli... περισσότερα »
Exploring the effects of synchronous pharyngeal electrical stimulation with swallowing carbonated water on cortical excitability in the human pharyngeal motor system.
*Exploring the effects of synchronous pharyngeal electrical stimulation with swallowing carbonated water on cortical excitability in the human pharyngeal motor system.* Neurogastroenterol Motil. 2016 Apr 8; Authors: Magara J, Michou E, Raginis-Zborowska A, Inoue M, Hamdy S Abstract BACKGROUND: Previous reports have revealed that excitation of human pharyngeal motor cortex can be induced by pharyngeal electrical stimulation (PES) and swallowing carbonated water (CW). This study investigated whether combining PES with swallowing (of still water, SW or CW) can potentiate this excita...περισσότερα »
Update on Therapeutic Interventions for the Management of Achalasia.
*Update on Therapeutic Interventions for the Management of Achalasia.* J Gastroenterol Hepatol. 2016 Apr 6; Authors: Gunasingam N, Perczuk A, Talbot M, Kaffes A, Saxena P Abstract Achalasia is a primary oesophageal motility disorder. It is the absence of peristalsis in the oesophageal body and inability of the lower oesophageal sphincter to relax that characterises this rare condition. It's features typically include dysphagia, regurgitation, chest pain and weight loss. The ultimate goal in treating achalasia is to relieve the patient's symptoms, improve oesophageal emptying and p... περισσότερα »
A comparison of the endoscopic and laparoscopic view of the gastroesophageal junction in the use of transoral fundoplication.
[image: http:--linkinghub.elsevier.com-ihub-imag] Related Articles *A comparison of the endoscopic and laparoscopic view of the gastroesophageal junction in the use of transoral fundoplication.* Am J Surg. 2015 Dec;210(6):1018-22; discussion 1022-3 Authors: Ihde GM, Dill LA, Lister DG, Lucchese CF, Cottrell C, Krone PK, Stone RA Abstract BACKGROUND: Endoscopic fundoplication requires accurate evaluation of the gastroesophageal junction (GJ) to determine if hiatal hernia repair is necessary before fundoplication. We compared the endoscopic and laparoscopic evaluations of the GJ. M... περισσότερα »
Incidence of gastroesophageal reflux disease (GERD), active component, U.S. Armed Forces, 2005-2014.
Related Articles *Incidence of gastroesophageal reflux disease (GERD), active component, U.S. Armed Forces, 2005-2014.* MSMR. 2015 Jul;22(7):14-7 Authors: Daniele DO, Oh GT, O'Donnell FL, Clark LL Abstract Gastroesophageal reflux disease (GERD) is a common condition among adults that can cause symptoms such as frequent heartburn, substernal chest pain, and regurgitation of food. During 2005-2014, a total of 137,081 active component service members had an incident (first-ever) diagnosis of GERD (incidence rate: 101.3 per 10,000 person-years). Incidence rates were higher than thei... περισσότερα »
Neonatal acute lymphocytic leukaemia: an unusual presentation of a rare disease.
[image: http:--highwire.stanford.edu-icons-exter] Related Articles *Neonatal acute lymphocytic leukaemia: an unusual presentation of a rare disease.* BMJ Case Rep. 2015;2015 Authors: Palman J, Karam M, Chee Y, Kandala V Abstract Infantile acute lymphocytic leukaemia (ALL) seldom presents within the first month of life. Most are diagnosed before birth. Postnatal diagnoses are easily recognisable when characteristic features are present, namely hepatosplenomegaly, leukaemia cutis or infiltrative disease of the extramedullar and central nervous system. However, some children present...περισσότερα »
Effect of peroral esophageal myotomy for achalasia treatment: A Chinese study.
[image: http:--http://ift.tt/1YyhL4R] [image: http:--http://ift.tt/1Fkw4zC] Related Articles *Effect of peroral esophageal myotomy for achalasia treatment: A Chinese study.* World J Gastroenterol. 2015 May 14;21(18):5622-9 Authors: Lu B, Li M, Hu Y, Xu Y, Zhang S, Cai LJ Abstract AIM: To assess the safety and feasibility of peroral esophageal myotomy (POEM) in patients with achalasia. METHODS: From January 2012 to March 2014, 50 patients (28 men, 22 women; mean age: 42.8 years, range: 14-70 years) underwent POEM. Pre- and postoperative symptoms were quantified using the Eckardt s... περισσότερα »
Effect of baclofen on the acid pocket at the gastroesophageal junction.
[image: http:--media.wiley.com-assets-7315-19-Wi] Related Articles *Effect of baclofen on the acid pocket at the gastroesophageal junction.* Dis Esophagus. 2015 Jul;28(5):488-95 Authors: Scarpellini E, Boecxstaens V, Farré R, Bisschops R, Dewulf D, Gasbarrini A, Pauwels A, Blondeau K, Tack J Abstract Previous studies established that a pocket of highly acidic gastric juice is present postprandially at the gastroesophageal junction in man. The GABA-B agonist baclofen inhibits postprandial reflux events through its effects on the lower esophageal sphincter (LES). The aim of the curr... περισσότερα »
Diabetes mellitus is an independent risk for gastroesophageal reflux disease among urban African Americans.
[image: http:--media.wiley.com-assets-7315-19-Wi] Related Articles *Diabetes mellitus is an independent risk for gastroesophageal reflux disease among urban African Americans.* Dis Esophagus. 2015 Jul;28(5):405-11 Authors: Natalini J, Palit A, Sankineni A, Friedenberg FK Abstract An association between gastroesophageal reflux disease (GERD) and diabetes mellitus (DM) has been reported. Studies have not been population-based and have failed to include a representative sample of African American subjects. The aim of the study was to determine if DM is independently associated with ... περισσότερα »
A comparison of the endoscopic and laparoscopic view of the gastroesophageal junction in the use of transoral fundoplication.
[image: http:--linkinghub.elsevier.com-ihub-imag] Related Articles *A comparison of the endoscopic and laparoscopic view of the gastroesophageal junction in the use of transoral fundoplication.* Am J Surg. 2015 Dec;210(6):1018-22; discussion 1022-3 Authors: Ihde GM, Dill LA, Lister DG, Lucchese CF, Cottrell C, Krone PK, Stone RA Abstract BACKGROUND: Endoscopic fundoplication requires accurate evaluation of the gastroesophageal junction (GJ) to determine if hiatal hernia repair is necessary before fundoplication. We compared the endoscopic and laparoscopic evaluations of the GJ. M... περισσότερα »
Incidence of gastroesophageal reflux disease (GERD), active component, U.S. Armed Forces, 2005-2014.
Related Articles *Incidence of gastroesophageal reflux disease (GERD), active component, U.S. Armed Forces, 2005-2014.* MSMR. 2015 Jul;22(7):14-7 Authors: Daniele DO, Oh GT, O'Donnell FL, Clark LL Abstract Gastroesophageal reflux disease (GERD) is a common condition among adults that can cause symptoms such as frequent heartburn, substernal chest pain, and regurgitation of food. During 2005-2014, a total of 137,081 active component service members had an incident (first-ever) diagnosis of GERD (incidence rate: 101.3 per 10,000 person-years). Incidence rates were higher than thei... περισσότερα »
Neonatal acute lymphocytic leukaemia: an unusual presentation of a rare disease.
[image: http:--highwire.stanford.edu-icons-exter] Related Articles *Neonatal acute lymphocytic leukaemia: an unusual presentation of a rare disease.* BMJ Case Rep. 2015;2015 Authors: Palman J, Karam M, Chee Y, Kandala V Abstract Infantile acute lymphocytic leukaemia (ALL) seldom presents within the first month of life. Most are diagnosed before birth. Postnatal diagnoses are easily recognisable when characteristic features are present, namely hepatosplenomegaly, leukaemia cutis or infiltrative disease of the extramedullar and central nervous system. However, some children present...περισσότερα »
Esophageal subepithelial lesion diagnosed as malignant gastrointestinal neuroectodermal tumor.
[image: http:--http://ift.tt/1YyhL4R] [image: http:--http://ift.tt/1Fkw4zC] Related Articles *Esophageal subepithelial lesion diagnosed as malignant gastrointestinal neuroectodermal tumor.* World J Gastroenterol. 2015 May 14;21(18):5739-43 Authors: Kim SB, Lee SH, Gu MJ Abstract A 21-year-old male visited our hospital with a complaint of aggravating dysphagia and odynophagia for a few days. Esophagogastroduodenoscopy showed huge bulging mucosa with an intact surface causing luminal narrowing at 35 cm from the incisor teeth. Endoscopic ultrasonography showed an about 35 mm sized ... περισσότερα »
Effect of peroral esophageal myotomy for achalasia treatment: A Chinese study.
[image: http:--http://ift.tt/1YyhL4R] [image: http:--http://ift.tt/1Fkw4zC] Related Articles *Effect of peroral esophageal myotomy for achalasia treatment: A Chinese study.* World J Gastroenterol. 2015 May 14;21(18):5622-9 Authors: Lu B, Li M, Hu Y, Xu Y, Zhang S, Cai LJ Abstract AIM: To assess the safety and feasibility of peroral esophageal myotomy (POEM) in patients with achalasia. METHODS: From January 2012 to March 2014, 50 patients (28 men, 22 women; mean age: 42.8 years, range: 14-70 years) underwent POEM. Pre- and postoperative symptoms were quantified using the Eckardt s... περισσότερα »
Shorter myotomy on the gastric site (≤2.5 cm) provides adequate relief of dysphagia in achalasia patients.
[image: http:--media.wiley.com-assets-7315-19-Wi] Related Articles *Shorter myotomy on the gastric site (≤2.5 cm) provides adequate relief of dysphagia in achalasia patients.* Dis Esophagus. 2015 Jul;28(5):412-7 Authors: Salvador R, Caruso V, Costantini M, Parise P, Nicoletti L, Cavallin F, Zanatta L, Bardini R, Ancona E, Zaninotto G Abstract The right length of the myotomy on the gastric side for esophageal achalasia is still a debated issue. We aimed to investigate the final outcome after classic myotomy (CM) as compared with a longer myotomy on the gastric side (LM) in two coh... περισσότερα »
The Timing and Effort of Lexical Access in Natural and Degraded Speech.
*The Timing and Effort of Lexical Access in Natural and Degraded Speech.* Front Psychol. 2016;7:398 Authors: Wagner AE, Toffanin P, Başkent D Abstract Understanding speech is effortless in ideal situations, and although adverse conditions, such as caused by hearing impairment, often render it an effortful task, they do not necessarily suspend speech comprehension. A prime example of this is speech perception by cochlear implant users, whose hearing prostheses transmit speech as a significantly degraded signal. It is yet unknown how mechanisms of speech processing deal with such de... περισσότερα »
The Timing and Effort of Lexical Access in Natural and Degraded Speech.
*The Timing and Effort of Lexical Access in Natural and Degraded Speech.* Front Psychol. 2016;7:398 Authors: Wagner AE, Toffanin P, Başkent D Abstract Understanding speech is effortless in ideal situations, and although adverse conditions, such as caused by hearing impairment, often render it an effortful task, they do not necessarily suspend speech comprehension. A prime example of this is speech perception by cochlear implant users, whose hearing prostheses transmit speech as a significantly degraded signal. It is yet unknown how mechanisms of speech processing deal with such de... περισσότερα »
Identification of a novel homozygous mutation in MYO3A in a Chinese family with DFNB30 non-syndromic hearing impairment.
*Identification of a novel homozygous mutation in MYO3A in a Chinese family with DFNB30 non-syndromic hearing impairment.* Int J Pediatr Otorhinolaryngol. 2016 May;84:43-7 Authors: Qu R, Sang Q, Xu Y, Feng R, Jin L, He L, Wang L Abstract INTRODUCTION: Hearing loss is a common sensory impairment. Several genetic loci or genes responsible for non-syndrome hearing loss have been identified, including the well-known deafness genes GJB2, MT-RNR1 and SLC26A4. MYO3A belongs to the myosin superfamily. Previously only three mutations in this gene have been found in an Isreali family with D... περισσότερα »
Delayed diagnosis of childhood deafness: the value of false negatives in the Programme for Early Detection of Neonatal Hearing Loss.
*Delayed diagnosis of childhood deafness: the value of false negatives in the Programme for Early Detection of Neonatal Hearing Loss.* Acta Otorrinolaringol Esp. 2016 Apr 6; Authors: Martínez-Pacheco MC, Ferrán de la Cierva L, García-Purriños FJ Abstract INTRODUCTION: Despite its importance, the existence of false negatives (patients who are told they hear well, but they have some degree of hipacusia) is rarely evaluated in programs for early detection of hearing loss. The aim of this study is to determine the variables that can lead to a delayed diagnosis, especially the existenc... περισσότερα »
Two novel mutations in ILDR1 gene cause autosomal recessive nonsyndromic hearing loss in consanguineous Iranian families.
Related Articles *Two novel mutations in ILDR1 gene cause autosomal recessive nonsyndromic hearing loss in consanguineous Iranian families.* J Genet. 2015 Sep;94(3):483-7 Authors: Mehrjoo Z, Babanejad M, Kahrizi K, Najmabadi H PMID: 26440088 [PubMed - indexed for MEDLINE] from #Audiology via xlomafota13 on Inoreader http://ift.tt/1WpezLc via IFTTT
The Timing and Effort of Lexical Access in Natural and Degraded Speech.
*The Timing and Effort of Lexical Access in Natural and Degraded Speech.* Front Psychol. 2016;7:398 Authors: Wagner AE, Toffanin P, Başkent D Abstract Understanding speech is effortless in ideal situations, and although adverse conditions, such as caused by hearing impairment, often render it an effortful task, they do not necessarily suspend speech comprehension. A prime example of this is speech perception by cochlear implant users, whose hearing prostheses transmit speech as a significantly degraded signal. It is yet unknown how mechanisms of speech processing deal with such de... περισσότερα »
Patient-Controlled Analgesia Plus Background Opioid Infusion for Postoperative Pain in Children
A Systematic Review and Meta-Analysis of Randomized Trials.: BACKGROUND: Bolus administration of opioids via a patient-controlled analgesia (PCA) device is widely used in the postoperative pediatric population. PCA devices have been shown to provide superior analgesia and greater patient satisfaction compared with intermittent administration. Studies comparing the efficacy of PCA with and without a background infusion for postoperative analgesia in children vary considerably in terms of dosing and methodologic quality, making it difficult for practitioners to derive clinically usefu...περισσότερα »
A 12-week DBPC dose-finding study with sublingual monomeric allergoid tablets in house dust mite allergic patients
A 12-week DBPC dose-finding study with sublingual monomeric allergoid tablets in house dust mite allergic patients: [image: cover.gif?v=1&s=eca9898eab49b7d92da2055c] Abstract Background In sublingual immunotherapy optimal doses are a key factor for therapeutic outcomes. The aim of this study with tablets containing carbamylated monomeric house dust mite allergoids was to determine the most effective and safe dose. Methods In this double-blind, placebo-controlled dose-finding study, 131 patients with house dust mite-induced allergic rhinoconjunctivitis were randomized to 12-week ... περισσότερα »
Η τεγκαφούρη (tegafur) αποτελεί ουσιαστικά προφάρμακο της 5-φθοριοουρακίλης μιάς και μετά την από το στόμα ή την ενδοφλέβια χορήγησή της διασπάται από την φωσφορυλάση της πυριμιδινονουκλεοσίδης και απελευθερώνεται 5-φθοριοουρακίλη που αποτελεί τον δραστικό αντινεοπλασματικό παράγοντα. Η τοξικότητά της είναι σημαντικά μικρότερη της 5-φθοριοουρακίλης ενώ η αποτελεσματικότητά της στον καρκίνο του παχέος εντέρου και του μαστού θεωρείται ότι υπερέχει εκείνης της 5-φθοριοουρακίλης.
Δραστική ουσία1 Τεγκαφούρη 1548R74NSZ - TEGAFUR Η τεγκαφούρη (tegafur) αποτελεί ουσιαστικά προφάρμακο της 5-φθοριοουρακίλης μιάς και μετά την από το στόμα ή την ενδοφλέβια χορήγησή της διασπάται από την φωσφορυλάση της πυριμιδινονουκλεοσίδης και απελευθερώνεται 5-φθοριοουρακίλη που αποτελεί τον δραστικό αντινεοπλασματικό παράγοντα. Η τοξικότητά της είναι σημαντικά μικρότερη της 5-φθοριοουρακίλης ενώ η αποτελεσματικότητά της στον καρκίνο του παχέος εντέρου και του μαστού θεωρείται ότι υπερέχει εκείνης της 5-φθοριοουρακίλης. 2 Φθοριουρακίλη U3P01618RT - FLUOROURACIL Η φθοριοουρακίλη (fl... περισσότερα »
Skin Image Retrieval Using Gabor Wavelet Texture Feature
Skin Image Retrieval Using Gabor Wavelet Texture Feature: Abstract Objective Skin imaging plays a key role in many clinical studies. We have used many skin imaging techniques, including the recently developed capacitive contact skin imaging based on fingerprint sensors. The aim of this study is to develop an effective skin image retrieval technique using Gabor wavelet transform, which can be used on different types of skin images, but with a special focus on skin capacitive contact images. Methods Content-based image retrieval (CBIR) is a useful technology to retrieve stored images ...περισσότερα »
High dose rate brachytherapy in early stage squamous-cell carcinoma of the lip.
Alexandros G. SfakianakisστοHead,Neck,Brain,Cervical Spine and Esophageal Cancers by Alexandros G. SfakianakisΠριν από 28 δευτερόλεπτα
*High dose rate brachytherapy in early stage squamous-cell carcinoma of the lip.* Acta Otorrinolaringol Esp. 2016 Apr 7; Authors: Mut A, Guinot JL, Arribas L, Díez-Presa L, Tortajada MI, Santos MÁ, Samper J, Santamaría P, Vendrell JB Abstract INTRODUCTION AND GOALS: To analyze the results obtained after treatment of early stage (T1-T2) squamous cell carcinoma of the lip with high dose rate brachytherapy and evaluate the efficacy of this treatment in both local and regional control. MATERIALS AND METHODS: Retrospective analysis of the treatments performed at our department from Ma... περισσότερα »
Glomuvenous Malformation of the Thermoregulatory Apparatus
Glomuvenous Malformation: A Rare Periorbital Lesion of the Thermoregulatory Apparatus.: Glomuvenous malformations (GVMs), previously referred to as glomus tumors or glomangiomas, are benign, mesenchymal venous malformations arising from glomus bodies. Glomus bodies are modified smooth muscle neuromyoarterial structures involved in temperature regulation via blood shunting. These classically occur in the digits but can occur in other locations. The authors present a case of a periorbital GVM presented following blunt trauma to the area. (C) 2016 by The American Society of Ophthalmic ...περισσότερα »
Concurrent cetuximab and postoperative radiation in resected high-risk squamous cell carcinomas of the head and neck: A single-institution experience.
Alexandros G. SfakianakisστοHead,Neck,Brain,Cervical Spine and Esophageal Cancers by Alexandros G. SfakianakisΠριν από 28 δευτερόλεπτα
*Concurrent cetuximab and postoperative radiation in resected high-risk squamous cell carcinomas of the head and neck: A single-institution experience.* Head Neck. 2016 Apr 7; Authors: Araki D, Redman MW, Martins R, Eaton K, Baik C, Chow L, Goulart B, Lee S, Santana-Davila R, Liao J, Parvathaneni U, Laramore G, Futran N, Mendez E, Bhrany A, Rodriguez CP Abstract BACKGROUND: Postoperative cisplatin and radiation is the standard of care for high-risk squamous cell carcinoma of the head and neck (SCCHN). We have used cetuximab and radiation in the postoperative setting for patients ... περισσότερα »
Factors influencing the incidence and prognosis of second primary tumors in patients with oral squamous cell carcinoma.
Alexandros G. SfakianakisστοHead,Neck,Brain,Cervical Spine and Esophageal Cancers by Alexandros G. SfakianakisΠριν από 28 δευτερόλεπτα
*Factors influencing the incidence and prognosis of second primary tumors in patients with oral squamous cell carcinoma.* Head Neck. 2016 Apr 7; Authors: Ko HH, Cheng SL, Lee JJ, Chen HM, Wang CW, Cheng SJ, Kok SH Abstract BACKGROUND: Although second primary tumors are common in patients with oral squamous cell carcinoma (OSCC), their predisposing factors and treatment guideline remain uncertain. METHODS: Three hundred ninety-four patients with OSCC who received radical surgery from January 2002 to December 2009 were retrospectively reviewed. RESULTS: Forty-five patients developed ... περισσότερα »
Brachytherapy after salvage surgery in cases with large isolated cervical recurrence of squamous cell carcinoma in the previously irradiated neck.
Alexandros G. SfakianakisστοHead,Neck,Brain,Cervical Spine and Esophageal Cancers by Alexandros G. SfakianakisΠριν από 28 δευτερόλεπτα
*Brachytherapy after salvage surgery in cases with large isolated cervical recurrence of squamous cell carcinoma in the previously irradiated neck.* Head Neck. 2016 Apr 9; Authors: Miroir J, Biau J, Saroul N, Moreira JF, Russier M, Lapeyre M Abstract BACKGROUND: Perioperative brachytherapy after salvage surgery is a therapeutic option in patients with cervical relapse of a primary, controlled, previously irradiated head and neck squamous cell carcinoma. The purpose of this study was to analyze the outcome of this treatment. METHODS: Between 2008 and 2013, 8 patients underwent cervi...περισσότερα »
Historical compliance rates for providing postoperative radiotherapy in oral cavity squamous cell carcinoma.
Alexandros G. SfakianakisστοHead,Neck,Brain,Cervical Spine and Esophageal Cancers by Alexandros G. SfakianakisΠριν από 28 δευτερόλεπτα
*Historical compliance rates for providing postoperative radiotherapy in oral cavity squamous cell carcinoma.* Head Neck. 2016 Apr 9; Authors: Hinther A, Nakoneshny SC, Dort JC, Chandarana SP, Matthews TW Abstract BACKGROUND: In 2014, Alberta Health Services released guidelines for treating oral squamous cell carcinoma (OSCC). METHODS: A retrospective analysis was performed to assess the historical selection of patients with OSCC for postoperative radiotherapy (PORT) in a prospectively collected cohort of patients being treated with primary surgery. The primary outcome was complia... περισσότερα »
Prognostic value of FDG-PET volumetric parameters in patients with p16-positive oropharyngeal squamous cell carcinoma who received curative resection followed by postoperative radiotherapy or chemoradiotherapy.
Alexandros G. SfakianakisστοHead,Neck,Brain,Cervical Spine and Esophageal Cancers by Alexandros G. SfakianakisΠριν από 28 δευτερόλεπτα
*Prognostic value of FDG-PET volumetric parameters in patients with p16-positive oropharyngeal squamous cell carcinoma who received curative resection followed by postoperative radiotherapy or chemoradiotherapy.* Head Neck. 2016 Apr 9; Authors: Kim KH, Lee J, Chang JS, Lee CG, Yun M, Choi EC, Kim SH, Keum KC Abstract BACKGROUND: The purpose of this study was to determine whether pretreatment 18F-fluorodeoxyglucose-positron emission tomography (FDG-PET) volumetric parameters add more prognostic information to p16-positive oropharyngeal squamous cell carcinoma (SCC). METHODS: We ret... περισσότερα »
Phase II trial of neoadjuvant chemotherapy with docetaxel, nedaplatin, and S1 for advanced esophageal squamous cell carcinoma.
Alexandros G. SfakianakisστοHead,Neck,Brain,Cervical Spine and Esophageal Cancers by Alexandros G. SfakianakisΠριν από 28 δευτερόλεπτα
*Phase II trial of neoadjuvant chemotherapy with docetaxel, nedaplatin, and S1 for advanced esophageal squamous cell carcinoma.* Cancer Sci. 2016 Apr 7; Authors: Tanaka Y, Yoshida K, Tanahashi T, Okumura N, Matsuhashi N, Yamaguchi K Abstract Although standard chemotherapy for esophageal cancer patients is fluorouracil and cisplatin (FP), the prognosis is still unsatisfactory. A new therapeutic regimen combining docetaxel, cisplatin, and 5-Fu (DCF) was recently developed to improve both local and distant tumor control. We developed a new regimen of docetaxel, nedaplatin, and S1 (D...περισσότερα »
Outcomes of patients with loco-regionally recurrent or new primary squamous cell carcinomas of the head and neck treated with curative intent reirradiation at Mayo Clinic.
Alexandros G. SfakianakisστοHead,Neck,Brain,Cervical Spine and Esophageal Cancers by Alexandros G. SfakianakisΠριν από 28 δευτερόλεπτα
*Outcomes of patients with loco-regionally recurrent or new primary squamous cell carcinomas of the head and neck treated with curative intent reirradiation at Mayo Clinic.* Radiat Oncol. 2016;11(1):55 Authors: Curtis KK, Ross HJ, Garrett AL, Jizba TA, Patel AB, Patel SH, Wong WW, Halyard MY, Ko SJ, Kosiorek HE, Foote RL Abstract BACKGROUND: We reviewed outcomes of patients with loco-regionally recurrent (LRR) or new primary (NP) squamous cell carcinoma of the head and neck (SCCHN) treated at our institution with reirradiation (RRT). METHODS: Patients received definitive RRT (DRRT...περισσότερα »
Concurrent cetuximab and postoperative radiation in resected high-risk squamous cell carcinomas of the head and neck: A single-institution experience.
Alexandros G. SfakianakisστοHead,Neck,Brain,Cervical Spine and Esophageal Cancers by Alexandros G. SfakianakisΠριν από 28 δευτερόλεπτα
*Concurrent cetuximab and postoperative radiation in resected high-risk squamous cell carcinomas of the head and neck: A single-institution experience.* Head Neck. 2016 Apr 7; Authors: Araki D, Redman MW, Martins R, Eaton K, Baik C, Chow L, Goulart B, Lee S, Santana-Davila R, Liao J, Parvathaneni U, Laramore G, Futran N, Mendez E, Bhrany A, Rodriguez CP Abstract BACKGROUND: Postoperative cisplatin and radiation is the standard of care for high-risk squamous cell carcinoma of the head and neck (SCCHN). We have used cetuximab and radiation in the postoperative setting for patients ... περισσότερα »
Tumour thickness as a determinant of nodal metastasis in oral tongue carcinoma.
Alexandros G. SfakianakisστοHead,Neck,Brain,Cervical Spine and Esophageal Cancers by Alexandros G. SfakianakisΠριν από 28 δευτερόλεπτα
*Tumour thickness as a determinant of nodal metastasis in oral tongue carcinoma.* ANZ J Surg. 2016 Apr 8; Authors: Wang K, Veivers D Abstract BACKGROUND: Tumour thickness is a strong predictor for cervical node involvement in oral cavity squamous cell carcinomas (SCCs), with a recent meta-analysis concluding a 4-mm optimal prognostic cut-off point. No consensus has been reached for the tumour thickness cut-off for oral tongue SCCs. METHODS: A retrospective review of prospectively collected data from 112 patients by the Northern Sydney Cancer Centre (Australia) with primary oral ...περισσότερα »
Human papilloma virus status evaluation and survival description in selected oropharyngeal and laryngeal squamous cell carcinoma patients from Hungary.
Alexandros G. SfakianakisστοHead,Neck,Brain,Cervical Spine and Esophageal Cancers by Alexandros G. SfakianakisΠριν από 28 δευτερόλεπτα
*Human papilloma virus status evaluation and survival description in selected oropharyngeal and laryngeal squamous cell carcinoma patients from Hungary.* J BUON. 2016 Jan-Mar;21(1):168-74 Authors: Reka Fejer E, Abram Z, Zs Egyed J, Voidazan S, Toth E, Szentirmay Z, Kasler M Abstract PURPOSE: Many patients with oropharyngeal squamous cell carcinomas do not have any of the traditional risk factors associated with head and neck squamous cell cancers (HNSCC). Epidemiologic and molecular studies have identified human papillomavirus (HPV) as a causative agent, viral tumors presenting ... περισσότερα »
Volumetric regression ratio of the primary tumor and metastatic lymph nodes after induction chemotherapy predicts overall survival in head and neck squamous cell carcinoma: a retrospective analysis.
Alexandros G. SfakianakisστοHead,Neck,Brain,Cervical Spine and Esophageal Cancers by Alexandros G. SfakianakisΠριν από 28 δευτερόλεπτα
*Volumetric regression ratio of the primary tumor and metastatic lymph nodes after induction chemotherapy predicts overall survival in head and neck squamous cell carcinoma: a retrospective analysis.* J BUON. 2016 Jan-Mar;21(1):175-81 Authors: Elicin O, Schmucking M, Bromme J, Rauch D, Ambarcioglu P, Plasswilm L, Geretschlager A, Ghadjar P, Giger R, Aebersold DM Abstract PURPOSE: We looked for any predictive value of change in primary tumor and metastatic lymph node volumes after induction chemotherapy (IC) on oncologic outcome in head and neck squamous cell carcinoma (HNSCC). MET... περισσότερα »
Factors influencing the incidence and prognosis of second primary tumors in patients with oral squamous cell carcinoma.
Alexandros G. SfakianakisστοHead,Neck,Brain,Cervical Spine and Esophageal Cancers by Alexandros G. SfakianakisΠριν από 28 δευτερόλεπτα
*Factors influencing the incidence and prognosis of second primary tumors in patients with oral squamous cell carcinoma.* Head Neck. 2016 Apr 7; Authors: Ko HH, Cheng SL, Lee JJ, Chen HM, Wang CW, Cheng SJ, Kok SH Abstract BACKGROUND: Although second primary tumors are common in patients with oral squamous cell carcinoma (OSCC), their predisposing factors and treatment guideline remain uncertain. METHODS: Three hundred ninety-four patients with OSCC who received radical surgery from January 2002 to December 2009 were retrospectively reviewed. RESULTS: Forty-five patients developed ... περισσότερα »
Brachytherapy after salvage surgery in cases with large isolated cervical recurrence of squamous cell carcinoma in the previously irradiated neck.
Alexandros G. SfakianakisστοHead,Neck,Brain,Cervical Spine and Esophageal Cancers by Alexandros G. SfakianakisΠριν από 28 δευτερόλεπτα
*Brachytherapy after salvage surgery in cases with large isolated cervical recurrence of squamous cell carcinoma in the previously irradiated neck.* Head Neck. 2016 Apr 9; Authors: Miroir J, Biau J, Saroul N, Moreira JF, Russier M, Lapeyre M Abstract BACKGROUND: Perioperative brachytherapy after salvage surgery is a therapeutic option in patients with cervical relapse of a primary, controlled, previously irradiated head and neck squamous cell carcinoma. The purpose of this study was to analyze the outcome of this treatment. METHODS: Between 2008 and 2013, 8 patients underwent cervi...περισσότερα »
Hyaluronic Acid Gel Injection for Multiple Eyelid Folds
in Asian Eyelids: A Novel Approach.: Purpose: Upper eyelids of the Asian population have several unique anatomical characteristics that result in the characteristic absence of a native eyelid fold; however, 40% to 60% of the Asian population do exhibit a naturally occurring fold. Aging-associated soft tissue atrophy and loss of skin elasticity can lead to periorbital volume loss and subsequent development of multiple eyelid folds in patients previously with a native single-fold. The authors describe a nonsurgical technique for the management of multiple eyelid folds in Asian patien... περισσότερα »
Proptosis Reduction Using Sirolimus in a Child
a Child With an Orbital Vascular Malformation and Blue Rubber Bleb Nevus Syndrome.: A 15-month-old boy with left congenital proptosis presented to the emergency department with melena. Upper GI endoscopy and magnetic resonance angiography revealed vascular lesions, consistent with gastrointestinal tract manifestations of blue rubber bleb nevus syndrome. MRI revealed vascular malformations in both orbits, with mass effect on the left side. The patient was started on a trial of the antiangiogenic agent sirolimus (also known as rapamycin), and after 6 months of treatment showed clinic...περισσότερα »
Partially Cystic Frontal Nerve Schwannoma Masquerading as Abducens Nerve Paresis.
Partially Cystic Frontal Nerve Schwannoma Masquerading as Abducens Nerve Paresis.:
Clinical implications of the Extension of platysmal Fibers on the Middle and Lower Faces.
Clinical implications of the Extension of platysmal Fibers on the Middle and Lower Faces.: Background: Despite the area of insertion of the facial portion of platysma being broad and highly variable, the details of its pattern of extension and morphology are not well described in the medical literature. The aim of this study was to clarify the extension patterns of the platysma on the middle and lower face by topographic examination and detailed dissection. Methods: A detailed dissection was performed in the cheek region of 34 cadaveric specimens. The anatomic aspects of the extent ... περισσότερα »
The length of the axillary nerve (AN) that is able to be dissected through a standard anterior (deltopectoral) and posterior approach
ANATOMICAL STUDY OF THE AXILLARY NERVE: DESCRIPTION OF A SURGICAL BLIND ZONE.: Introduction: The aim of this study is to quantify the length of the axillary nerve (AN) that is able to be dissected through a standard anterior (deltopectoral) and posterior approach. We hypothesize that a segment of the AN cannot be reached using both approaches simultaneously. Material and Methods: ANs of 5 frozen cadavers were dissected using an anterior and posterior approach. A first surgical clip marked the most visible distal part of the nerve from the deltopectoral approach; a second surgical cl...περισσότερα »
speech and language; +36 new citations
36 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: *speech and language* These pubmed results were generated on 2016/04/12 PubMed comprises more than 24 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites. from Speech via xlomafota13 on Inoreader http://ift.tt/1RR2vR8 via IFTTT
speech and language; +36 new citations
36 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: *speech and language* These pubmed results were generated on 2016/04/12 PubMed comprises more than 24 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites. from Speech via xlomafota13 on Inoreader http://ift.tt/1RR2vR8
Relationships between vocal function measures derived from an acoustic microphone and a subglottal neck-surface accelerometer.
*Relationships between vocal function measures derived from an acoustic microphone and a subglottal neck-surface accelerometer.* IEEE/ACM Trans Audio Speech Lang Process. 2016 Apr;24(4):659-668 Authors: Mehta DD, Van Stan JH, Hillman RE Abstract Monitoring subglottal neck-surface acceleration has received renewed attention due to the ability of low-profile accelerometers to confidentially and noninvasively track properties related to normal and disordered voice characteristics and behavior. This study investigated the ability of subglottal neck-surface acceleration to yield vocal ...περισσότερα »
Juniors' voice: Opportunities for ERS 'junior members in 2016.
*Juniors' voice: Opportunities for ERS 'junior members in 2016.* Breathe (Sheff). 2016 Mar;12(1):69-71 Authors: Boots A, Flood E, Skoczynski S Abstract Opportunities for ERS junior members in 2016 http://ow.ly/YC7ME. PMID: 27066139 [PubMed - as supplied by publisher] from Speech via xlomafota13 on Inoreader http://ift.tt/1T148un
Juniors' voice at the ERS International Congress, Amsterdam 2015: Juniors' voice.
*Juniors' voice at the ERS International Congress, Amsterdam 2015: Juniors' voice.* Breathe (Sheff). 2015 Dec;11(4):303-305 Authors: Polverino F, Longhini F, Vanaudenaerde B, Bikov A, Aamli A, Singanayagam A, Kahn N, Boots A, Skoczynski S Abstract The Juniors' voice at the ERS International Congress http://ow.ly/ULcej. PMID: 27066124 [PubMed - as supplied by publisher] from Speech via xlomafota13 on Inoreader http://ift.tt/1S6ZVoT
Evaluation of Analytical Modeling Functions for the Phonation Onset Process.
*Evaluation of Analytical Modeling Functions for the Phonation Onset Process.* Comput Math Methods Med. 2016;2016:8469139 Authors: Petermann S, Kniesburges S, Ziethe A, Schützenberger A, Döllinger M Abstract The human voice originates from oscillations of the vocal folds in the larynx. The duration of the voice onset (VO), called the voice onset time (VOT), is currently under investigation as a clinical indicator for correct laryngeal functionality. Different analytical approaches for computing the VOT based on endoscopic imaging were compared to determine the most reliable metho...περισσότερα »
Establishing the "Fit" between the Patient and the Therapy: The Role of Patient Gender in Selecting Psychological Therapy for Distressing Voices.
*Establishing the "Fit" between the Patient and the Therapy: The Role of Patient Gender in Selecting Psychological Therapy for Distressing Voices.* Front Psychol. 2016;7:424 Authors: Hayward M, Slater L, Berry K, Perona-Garcelán S Abstract The experience of hearing distressing voices has recently attracted much attention in the literature on psychological therapies. A new "wave" of therapies is considering voice hearing experiences within a relational framework. However, such therapies may have limited impact if they do not precisely target key psychological variables within the v... περισσότερα »
Structural Classification of Wild Boar (Sus scrofa) Vocalizations.
*Structural Classification of Wild Boar (Sus scrofa) Vocalizations.* Ethology. 2016 Apr;122(4):329-342 Authors: Garcia M, Gingras B, Bowling DL, Herbst CT, Boeckle M, Locatelli Y, Fitch WT Abstract Determining whether a species' vocal communication system is graded or discrete requires definition of its vocal repertoire. In this context, research on domestic pig (Sus scrofa domesticus) vocalizations, for example, has led to significant advances in our understanding of communicative functions. Despite their close relation to domestic pigs, little is known about wild boar (Sus scro...περισσότερα »
Associations between self-perceived voice disorders in teachers, perceptual assessment by speech-language pathologists, and instrumental analysis.
*Associations between self-perceived voice disorders in teachers, perceptual assessment by speech-language pathologists, and instrumental analysis.* Int J Speech Lang Pathol. 2016 Mar 24;:1-10 Authors: Cantor Cutiva LC, Fajardo A, Burdorf A Abstract PURPOSE: The three aims of this study were to assess agreement between self-perceived voice disorders, perceptual and instrumental assessment; to determine factors associated with perceptual voice assessment; and to determine which associated factors would serve as an initial screening tool for ascertainment of the presence or absence...περισσότερα »
Student voice - A degree of quality.
*Student voice - A degree of quality.* Nurs Child Young People. 2016 Apr 11;28(3):14 Authors: Cowen E Abstract IN DECEMBER the government announced plans to develop a new healthcare role, the nursing associate. Consultation continues on what this role will entail, but the training route has been announced as an apprenticeship, and it has been described as a way to avoid the degree-only route to becoming a nurse. PMID: 27063048 [PubMed - in process] from Speech via xlomafota13 on Inoreader http://ift.tt/1TOvpmh
Age- and sex-related variations in vocal-tract morphology and voice acoustics during adolescence.
*Age- and sex-related variations in vocal-tract morphology and voice acoustics during adolescence.* Horm Behav. 2016 Apr 7; Authors: Markova D, Richer L, Pangelinan M, Schwartz DH, Leonard G, Perron M, Pike GB, Veillette S, Chakravarty MM, Pausova Z, Paus T Abstract Distinct differences in the human voice emerge during adolescence, with males producing deeper and more resonant voices than females by the end of sexual maturation. Using magnetic resonance images of heads and voice recordings obtained in 532 typically developing adolescents, we investigate what might be the drivers ...περισσότερα »
Tremor in dystonia.
*Tremor in dystonia.* Parkinsonism Relat Disord. 2016 Apr 1; Authors: Pandey S, Sarma N Abstract Tremor has been recognized as an important clinical feature in dystonia. Tremor in dystonia may occur in the body part affected by dystonia known as dystonic tremor or unaffected body regions known as tremor associated with dystonia. The most common type of tremor seen in dystonia patients is postural and kinetic which may be mistaken for familial essential tremor. Similarly familial essential tremor patients may have associated dystonia leading to diagnostic uncertainties. The pathog...περισσότερα »
'Global health' and 'global nursing': proposed definitions from The Global Advisory Panel on the Future of Nursing.
*'Global health' and 'global nursing': proposed definitions from The Global Advisory Panel on the Future of Nursing.* J Adv Nurs. 2016 Apr 8; Authors: Wilson L, Mendes IA, Klopper H, Catrambone C, Al-Maaitah R, Norton ME, Hill M Abstract AIMS: To propose definitions of global health and global nursing that reflect the new paradigm that integrates domestic and international health. BACKGROUND: Increased globalization has led to expanded awareness of the importance of global health and global nursing among students and faculty in the health professions and among policymakers and pra...περισσότερα »
The encoding of word forms into memory may be challenging for college students with developmental language impairment
10.3109/17549507.2016.1159337<br>Karla McGregor from Speech via xlomafota13 on Inoreader http://ift.tt/1RQUVWs
Relationships between vocal function measures derived from an acoustic microphone and a subglottal neck-surface accelerometer.
*Relationships between vocal function measures derived from an acoustic microphone and a subglottal neck-surface accelerometer.* IEEE/ACM Trans Audio Speech Lang Process. 2016 Apr;24(4):659-668 Authors: Mehta DD, Van Stan JH, Hillman RE Abstract Monitoring subglottal neck-surface acceleration has received renewed attention due to the ability of low-profile accelerometers to confidentially and noninvasively track properties related to normal and disordered voice characteristics and behavior. This study investigated the ability of subglottal neck-surface acceleration to yield vocal ...περισσότερα »
Juniors' voice: Opportunities for ERS 'junior members in 2016.
*Juniors' voice: Opportunities for ERS 'junior members in 2016.* Breathe (Sheff). 2016 Mar;12(1):69-71 Authors: Boots A, Flood E, Skoczynski S Abstract Opportunities for ERS junior members in 2016 http://ow.ly/YC7ME. PMID: 27066139 [PubMed - as supplied by publisher] from Speech via xlomafota13 on Inoreader http://ift.tt/1T148un via IFTTT
Juniors' voice at the ERS International Congress, Amsterdam 2015: Juniors' voice.
*Juniors' voice at the ERS International Congress, Amsterdam 2015: Juniors' voice.* Breathe (Sheff). 2015 Dec;11(4):303-305 Authors: Polverino F, Longhini F, Vanaudenaerde B, Bikov A, Aamli A, Singanayagam A, Kahn N, Boots A, Skoczynski S Abstract The Juniors' voice at the ERS International Congress http://ow.ly/ULcej. PMID: 27066124 [PubMed - as supplied by publisher] from Speech via xlomafota13 on Inoreader http://ift.tt/1S6ZVoT via IFTTT
Evaluation of Analytical Modeling Functions for the Phonation Onset Process.
*Evaluation of Analytical Modeling Functions for the Phonation Onset Process.* Comput Math Methods Med. 2016;2016:8469139 Authors: Petermann S, Kniesburges S, Ziethe A, Schützenberger A, Döllinger M Abstract The human voice originates from oscillations of the vocal folds in the larynx. The duration of the voice onset (VO), called the voice onset time (VOT), is currently under investigation as a clinical indicator for correct laryngeal functionality. Different analytical approaches for computing the VOT based on endoscopic imaging were compared to determine the most reliable metho...περισσότερα »
Establishing the "Fit" between the Patient and the Therapy: The Role of Patient Gender in Selecting Psychological Therapy for Distressing Voices.
*Establishing the "Fit" between the Patient and the Therapy: The Role of Patient Gender in Selecting Psychological Therapy for Distressing Voices.* Front Psychol. 2016;7:424 Authors: Hayward M, Slater L, Berry K, Perona-Garcelán S Abstract The experience of hearing distressing voices has recently attracted much attention in the literature on psychological therapies. A new "wave" of therapies is considering voice hearing experiences within a relational framework. However, such therapies may have limited impact if they do not precisely target key psychological variables within the v... περισσότερα »
Structural Classification of Wild Boar (Sus scrofa) Vocalizations.
*Structural Classification of Wild Boar (Sus scrofa) Vocalizations.* Ethology. 2016 Apr;122(4):329-342 Authors: Garcia M, Gingras B, Bowling DL, Herbst CT, Boeckle M, Locatelli Y, Fitch WT Abstract Determining whether a species' vocal communication system is graded or discrete requires definition of its vocal repertoire. In this context, research on domestic pig (Sus scrofa domesticus) vocalizations, for example, has led to significant advances in our understanding of communicative functions. Despite their close relation to domestic pigs, little is known about wild boar (Sus scro...περισσότερα »
Associations between self-perceived voice disorders in teachers, perceptual assessment by speech-language pathologists, and instrumental analysis.
*Associations between self-perceived voice disorders in teachers, perceptual assessment by speech-language pathologists, and instrumental analysis.* Int J Speech Lang Pathol. 2016 Mar 24;:1-10 Authors: Cantor Cutiva LC, Fajardo A, Burdorf A Abstract PURPOSE: The three aims of this study were to assess agreement between self-perceived voice disorders, perceptual and instrumental assessment; to determine factors associated with perceptual voice assessment; and to determine which associated factors would serve as an initial screening tool for ascertainment of the presence or absence...περισσότερα »
Student voice - A degree of quality.
*Student voice - A degree of quality.* Nurs Child Young People. 2016 Apr 11;28(3):14 Authors: Cowen E Abstract IN DECEMBER the government announced plans to develop a new healthcare role, the nursing associate. Consultation continues on what this role will entail, but the training route has been announced as an apprenticeship, and it has been described as a way to avoid the degree-only route to becoming a nurse. PMID: 27063048 [PubMed - in process] from Speech via xlomafota13 on Inoreader http://ift.tt/1TOvpmh via IFTTT
Extending the duration of chemoprophylaxis following free flap harvest from the lower extremity for deep venous thrombosis
Evidence for extending the duration of chemoprophylaxis following free flap harvest from the lower extremity: Prospective screening for deep venous thrombosis*+.: Background: The purpose of this study was to investigate the incidence of symptomatic and asymptomatic deep venous thrombosis (DVT) in patients undergoing harvest of a free flap from the lower extremity who were receiving standard chemoprophylaxis while hospitalized. Methods: A retrospective review of 65 consecutive patients undergoing surgery between 2011 and 2013 was performed to determine the incidence of symptomatic DV... περισσότερα »
Mandible Fracture Complications and Infection
The Influence of Demographics and Modifiable Factors.: Background: Previous studies assessing outcomes following orthognathic surgery primarily rely upon single-center/surgeon experience. In addition to issues of generalizability, these studies are limited in evaluating the effect of operative volume on patient outcomes. Methods: Orthognathic procedures were identified in the 1999-2011 HCUP Nationwide Inpatient Sample. Outcomes included occurrence of any in-hospital complication, extended length of stay (LOS) (>2 days), and increased costs (>$10,784). High-volume hospitals were def... περισσότερα »
Lymphovenous Anastomoses
Long-Tem Patency of Lymphovenous Anastomoses: A Systematic Review.: Background: With the advancements in technology and microsurgical techniques lymphovenous anastomosis (LVA) has become a popular reconstructive procedure in the treatment of chronic lymphedema. However the long-term patency of these anastomoses is not clear in the literature. Methods: A systemic review of the MEDLINE and EMBASE databases was done to assess the reported long-term patency of lymphovenous anastomoses. Results: A total of 8 studies satisfied the inclusion criteria. Pooled data from four similar experime... περισσότερα »
Perforator Mapping and Optimizing Design of the Lateral Arm Flap
: Anatomy Revisited and Clinical Experience.: Introduction: The lateral arm flap remains an underutilized flap especially as a free flap. Here, we describe the perforator anatomy to optimize flap design and harvest. Methods: Perforator locations were mapped in 12 cadavers (24 arms), including a retrospective review of 51 patients undergoing a lateral arm flap. Results: One to 3 reliable perforators supply the lateral arm flap. Based on cadaveric dissections, from the deltoid insertion, the A, B, and C perforators were located at 7.2+/-1.0cm, 9.9+/-1.2cm, and 11.8+/-0.8cm which was ... περισσότερα »
Biologists discover new strategy to treat central nervous system injury
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 33 δευτερόλεπτα
Neurobiologists at UC San Diego have discovered how signals that orchestrate the construction of the nervous system also influence recovery after traumatic injury. from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1Wpe4ky via IFTTT
Researchers identify tissue biomarker for dementia with lewy bodies and Parkinson’s disease
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 33 δευτερόλεπτα
Accurate diagnosis of Parkinson’s disease, and the related disease «dementia with Lewy bodies,» can be difficult in the early stages of both conditions. from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/22r3xVt via IFTTT
Pain Control in the Presence of Drug Addiction
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 33 δευτερόλεπτα
Abstract Drug addiction is present in a significant proportion of the population in the USA and worldwide. Drug addiction can occur with the abuse of many types of substances including cocaine, marijuana, stimulants, alcohol, opioids, and tranquilizers. There is a high likelihood that clinicians will encounter patients with substance abuse disorders on a regular basis […]
Viruses, Vol. 8, Pages 96: Current Approaches for Diagnosis of Influenza Virus Infections in Humans
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 33 δευτερόλεπτα
Despite significant advancement in vaccine and virus research, influenza continues to be a major public health concern. Each year in the United States of America, influenza viruses are responsible for seasonal epidemics resulting in over 200,000 hospitalizations and 30,000–50,000 deaths. Accurate and early diagnosis of influenza viral infections are critical for rapid initiation of antiviral […]
Detrimental health effects of benzene exposure in adults after a flaring disaster at the BP refinery plant in Texas City
Disaster Medicine and Public Health Preparedness from Emergency Medicine via xlomafota13 on Inoreader http://ift.tt/23r5C9K via IFTTT
A meta-analysis of percutenous compression plate versus intramedullary nail for treatment of intertrochanteric HIP fractures
International Journal of Surgery from Emergency Medicine via xlomafota13 on Inoreader http://ift.tt/1Nmguci via IFTTT
Characterizing Hospital Admissions to a Tertiary Care Hospital After Typhoon Haiyan
Disaster Medicine and Public Health Preparedness from Emergency Medicine via xlomafota13 on Inoreader http://ift.tt/23r5CXe via IFTTT
Discordance between Hemoconcentration and Clinical Assessment of Decongestion in Acute Heart Failure
Journal of Cardiac Failure from Emergency Medicine via xlomafota13 on Inoreader http://ift.tt/1Nmguc7 via IFTTT
Saving lives and protecting people from injuries and violence
Annals of Emergency Medicine from Emergency Medicine via xlomafota13 on Inoreader http://ift.tt/23r5A1C via IFTTT
Nonsteroidal anti-inflammatory drug toxicity in children: a clinical review
Pediatric Emergency Care from Emergency Medicine via xlomafota13 on Inoreader http://ift.tt/1NmgtVK via IFTTT
Abdominal compartment syndrome in trauma patients: New insights for predicting outcomes
Journal of Emergencies, Trauma and Shock from Emergency Medicine via xlomafota13 on Inoreader http://ift.tt/23r5BCJ via IFTTT
Management of maxillofacial trauma in emergency: An update of challenges and controversies
Journal of Emergencies, Trauma and Shock from Emergency Medicine via xlomafota13 on Inoreader http://ift.tt/1NmgtVA via IFTTT
Mechanical ventilation in critical care transport
Air Medical Journal from Emergency Medicine via xlomafota13 on Inoreader http://ift.tt/23r5BCz via IFTTT
Effort-reward imbalance and post-traumatic stress after a workplace terror attack
Disaster Medicine and Public Health Preparedness from Emergency Medicine via xlomafota13 on Inoreader http://ift.tt/1NmgtF8 via IFTTT
KDIGO-based acute kidney injury criteria operate differently in hospitals and the community - findings from a large population cohort
Nephrology Dialysis Transplantation from Emergency Medicine via xlomafota13 on Inoreader http://ift.tt/23r5zKX via IFTTT
Traumatic injuries in patients with diabetes mellitus
Journal of Emergencies, Trauma and Shock from Emergency Medicine via xlomafota13 on Inoreader http://ift.tt/1NmgtoN via IFTTT
Optimal dosing of IV ketamine for procedural sedation in children in the emergency department - a randomized controlled trial
The American Journal of Emergency Medicine from Emergency Medicine via xlomafota13 on Inoreader http://ift.tt/23r5B5D via IFTTT
When extracorporeal cardiopulmonary resuscitation fails – Fatal ionized hypocalcemia during cardiac arrest
The American Journal of Emergency Medicine from Emergency Medicine via xlomafota13 on Inoreader http://ift.tt/1NmgtoG via IFTTT
Diagnostic performance of initial serum lactate for predicting bacteremia in female patients with acute pyelonephritis
The American Journal of Emergency Medicine from Emergency Medicine via xlomafota13 on Inoreader http://ift.tt/23r5B5y via IFTTT
The association between limited english proficiency and unplanned emergency department revisit within 72 hours
Annals of Emergency Medicine from Emergency Medicine via xlomafota13 on Inoreader http://ift.tt/1Nmgrgy via IFTTT
A prediction model to identify patients without a concerning intra abdominal diagnosis
The American Journal of Emergency Medicine from Emergency Medicine via xlomafota13 on Inoreader http://ift.tt/23r5ze9 via IFTTT
Injury patterns and outcomes of ice-fishing in the United States
The American Journal of Emergency Medicine from Emergency Medicine via xlomafota13 on Inoreader http://ift.tt/1Nmgrgt via IFTTT
Emergency physicians seek their place in a pay-for-value world
Annals of Emergency Medicine from Emergency Medicine via xlomafota13 on Inoreader http://ift.tt/23r5AOZ via IFTTT
Phenotypic and molecular analyses of primary lateral sclerosis.
*Phenotypic and molecular analyses of primary lateral sclerosis.* Neurol Genet. 2015 Jun;1(1):e3 Authors: Mitsumoto H, Nagy PL, Gennings C, Murphy J, Andrews H, Goetz R, Floeter MK, Hupf J, Singleton J, Barohn RJ, Nations S, Shoesmith C, Kasarskis E, Factor-Litvak P Abstract OBJECTIVE: To understand phenotypic and molecular characteristics of patients with clinically "definite" primary lateral sclerosis (PLS) in a prospective study. METHODS: Six sites enrolled 41 patients who had pure upper motor neuron dysfunction, bulbar symptoms, a normal EMG done within 12 months of enrollmen...περισσότερα »
Esophageal Stricture Secondary to Candidiasis in a Child with Glycogen Storage Disease 1b.
*Esophageal Stricture Secondary to Candidiasis in a Child with Glycogen Storage Disease 1b.* Pediatr Gastroenterol Hepatol Nutr. 2016 Mar;19(1):71-75 Authors: Lee KJ, Choi SJ, Kim WS, Park SS, Moon JS, Ko JS Abstract Esophageal candidiasis is commonly seen in immunocompromised patients; however, candida esophagitis induced stricture is a very rare complication. We report the first case of esophageal stricture secondary to candidiasis in a glycogen storage disease (GSD) 1b child. The patient was diagnosed with GSD type 1b by liver biopsy. No mutation was found in the G6PC gene, bu... περισσότερα »
Foramen magnum meningioma: The midline suboccipital subtonsillar approach.
*Foramen magnum meningioma: The midline suboccipital subtonsillar approach.* Clin Neurol Neurosurg. 2016 Apr 2;145:28-34 Authors: Dobrowolski S, Ebner F, Lepski G, Tatagiba M Abstract OBJECTIVES: Foramen magnum meningiomas (FMMs) represent a technical challenge even for experienced neurosurgeons, because they grow in close contact with osteoarticular, nervous, and vascular structures that cannot be sacrificed or retracted during surgery. Our goal is to present our experience with 24 cases of surgically resected foramen magnum meningiomas used the midline suboccipital subtonsillar ... περισσότερα »
Why do clinicians choose the therapies and techniques they do? Exploring clinical decision-making via treatment selections in dysphagia practice.
*Why do clinicians choose the therapies and techniques they do? Exploring clinical decision-making via treatment selections in dysphagia practice.* Int J Speech Lang Pathol. 2016 Apr 7;:1-8 Authors: McCurtin A, Healy C Abstract PURPOSE: Speech-language pathologists (SLPs) are assumed to use evidence-based practice to inform treatment decisions. However, the reasoning underpinning treatment selections is not well known. Understanding why SLPs choose the treatments they do may be clarified by exploring the reasoning tied to specific treatments such as dysphagia interventions. METHO... περισσότερα »
Viscosity of thickened fluids that relate to the Australian National Standards.
*Viscosity of thickened fluids that relate to the Australian National Standards.* Int J Speech Lang Pathol. 2015 Oct 1;:1-9 Authors: Karsten Hadde E, Ann Yvette Cichero J, Michael Nicholson T Abstract PURPOSE: In 2007, Australia published standardized terminology and definitions for three levels of thickened fluids used in the management of dysphagia. This study examined the thickness of the current Australian National Fluid Standards rheologically (i.e. viscosity, yield stress) and correlated these results with the "fork test", as described in the national standards. METHOD: Cli... περισσότερα »
Exploring the effects of synchronous pharyngeal electrical stimulation with swallowing carbonated water on cortical excitability in the human pharyngeal motor system.
*Exploring the effects of synchronous pharyngeal electrical stimulation with swallowing carbonated water on cortical excitability in the human pharyngeal motor system.* Neurogastroenterol Motil. 2016 Apr 8; Authors: Magara J, Michou E, Raginis-Zborowska A, Inoue M, Hamdy S Abstract BACKGROUND: Previous reports have revealed that excitation of human pharyngeal motor cortex can be induced by pharyngeal electrical stimulation (PES) and swallowing carbonated water (CW). This study investigated whether combining PES with swallowing (of still water, SW or CW) can potentiate this excita...περισσότερα »
Update on Therapeutic Interventions for the Management of Achalasia.
*Update on Therapeutic Interventions for the Management of Achalasia.* J Gastroenterol Hepatol. 2016 Apr 6; Authors: Gunasingam N, Perczuk A, Talbot M, Kaffes A, Saxena P Abstract Achalasia is a primary oesophageal motility disorder. It is the absence of peristalsis in the oesophageal body and inability of the lower oesophageal sphincter to relax that characterises this rare condition. It's features typically include dysphagia, regurgitation, chest pain and weight loss. The ultimate goal in treating achalasia is to relieve the patient's symptoms, improve oesophageal emptying and p... περισσότερα »
A comparison of the endoscopic and laparoscopic view of the gastroesophageal junction in the use of transoral fundoplication.
[image: http:--linkinghub.elsevier.com-ihub-imag] Related Articles *A comparison of the endoscopic and laparoscopic view of the gastroesophageal junction in the use of transoral fundoplication.* Am J Surg. 2015 Dec;210(6):1018-22; discussion 1022-3 Authors: Ihde GM, Dill LA, Lister DG, Lucchese CF, Cottrell C, Krone PK, Stone RA Abstract BACKGROUND: Endoscopic fundoplication requires accurate evaluation of the gastroesophageal junction (GJ) to determine if hiatal hernia repair is necessary before fundoplication. We compared the endoscopic and laparoscopic evaluations of the GJ. M... περισσότερα »
Incidence of gastroesophageal reflux disease (GERD), active component, U.S. Armed Forces, 2005-2014.
Related Articles *Incidence of gastroesophageal reflux disease (GERD), active component, U.S. Armed Forces, 2005-2014.* MSMR. 2015 Jul;22(7):14-7 Authors: Daniele DO, Oh GT, O'Donnell FL, Clark LL Abstract Gastroesophageal reflux disease (GERD) is a common condition among adults that can cause symptoms such as frequent heartburn, substernal chest pain, and regurgitation of food. During 2005-2014, a total of 137,081 active component service members had an incident (first-ever) diagnosis of GERD (incidence rate: 101.3 per 10,000 person-years). Incidence rates were higher than thei... περισσότερα »
Neonatal acute lymphocytic leukaemia: an unusual presentation of a rare disease.
[image: http:--highwire.stanford.edu-icons-exter] Related Articles *Neonatal acute lymphocytic leukaemia: an unusual presentation of a rare disease.* BMJ Case Rep. 2015;2015 Authors: Palman J, Karam M, Chee Y, Kandala V Abstract Infantile acute lymphocytic leukaemia (ALL) seldom presents within the first month of life. Most are diagnosed before birth. Postnatal diagnoses are easily recognisable when characteristic features are present, namely hepatosplenomegaly, leukaemia cutis or infiltrative disease of the extramedullar and central nervous system. However, some children present...περισσότερα »
Effect of peroral esophageal myotomy for achalasia treatment: A Chinese study.
[image: http:--http://ift.tt/1YyhL4R] [image: http:--http://ift.tt/1Fkw4zC] Related Articles *Effect of peroral esophageal myotomy for achalasia treatment: A Chinese study.* World J Gastroenterol. 2015 May 14;21(18):5622-9 Authors: Lu B, Li M, Hu Y, Xu Y, Zhang S, Cai LJ Abstract AIM: To assess the safety and feasibility of peroral esophageal myotomy (POEM) in patients with achalasia. METHODS: From January 2012 to March 2014, 50 patients (28 men, 22 women; mean age: 42.8 years, range: 14-70 years) underwent POEM. Pre- and postoperative symptoms were quantified using the Eckardt s... περισσότερα »
Effect of baclofen on the acid pocket at the gastroesophageal junction.
[image: http:--media.wiley.com-assets-7315-19-Wi] Related Articles *Effect of baclofen on the acid pocket at the gastroesophageal junction.* Dis Esophagus. 2015 Jul;28(5):488-95 Authors: Scarpellini E, Boecxstaens V, Farré R, Bisschops R, Dewulf D, Gasbarrini A, Pauwels A, Blondeau K, Tack J Abstract Previous studies established that a pocket of highly acidic gastric juice is present postprandially at the gastroesophageal junction in man. The GABA-B agonist baclofen inhibits postprandial reflux events through its effects on the lower esophageal sphincter (LES). The aim of the curr... περισσότερα »
Diabetes mellitus is an independent risk for gastroesophageal reflux disease among urban African Americans.
[image: http:--media.wiley.com-assets-7315-19-Wi] Related Articles *Diabetes mellitus is an independent risk for gastroesophageal reflux disease among urban African Americans.* Dis Esophagus. 2015 Jul;28(5):405-11 Authors: Natalini J, Palit A, Sankineni A, Friedenberg FK Abstract An association between gastroesophageal reflux disease (GERD) and diabetes mellitus (DM) has been reported. Studies have not been population-based and have failed to include a representative sample of African American subjects. The aim of the study was to determine if DM is independently associated with ... περισσότερα »
A comparison of the endoscopic and laparoscopic view of the gastroesophageal junction in the use of transoral fundoplication.
[image: http:--linkinghub.elsevier.com-ihub-imag] Related Articles *A comparison of the endoscopic and laparoscopic view of the gastroesophageal junction in the use of transoral fundoplication.* Am J Surg. 2015 Dec;210(6):1018-22; discussion 1022-3 Authors: Ihde GM, Dill LA, Lister DG, Lucchese CF, Cottrell C, Krone PK, Stone RA Abstract BACKGROUND: Endoscopic fundoplication requires accurate evaluation of the gastroesophageal junction (GJ) to determine if hiatal hernia repair is necessary before fundoplication. We compared the endoscopic and laparoscopic evaluations of the GJ. M... περισσότερα »
Incidence of gastroesophageal reflux disease (GERD), active component, U.S. Armed Forces, 2005-2014.
Related Articles *Incidence of gastroesophageal reflux disease (GERD), active component, U.S. Armed Forces, 2005-2014.* MSMR. 2015 Jul;22(7):14-7 Authors: Daniele DO, Oh GT, O'Donnell FL, Clark LL Abstract Gastroesophageal reflux disease (GERD) is a common condition among adults that can cause symptoms such as frequent heartburn, substernal chest pain, and regurgitation of food. During 2005-2014, a total of 137,081 active component service members had an incident (first-ever) diagnosis of GERD (incidence rate: 101.3 per 10,000 person-years). Incidence rates were higher than thei... περισσότερα »
Neonatal acute lymphocytic leukaemia: an unusual presentation of a rare disease.
[image: http:--highwire.stanford.edu-icons-exter] Related Articles *Neonatal acute lymphocytic leukaemia: an unusual presentation of a rare disease.* BMJ Case Rep. 2015;2015 Authors: Palman J, Karam M, Chee Y, Kandala V Abstract Infantile acute lymphocytic leukaemia (ALL) seldom presents within the first month of life. Most are diagnosed before birth. Postnatal diagnoses are easily recognisable when characteristic features are present, namely hepatosplenomegaly, leukaemia cutis or infiltrative disease of the extramedullar and central nervous system. However, some children present...περισσότερα »
Esophageal subepithelial lesion diagnosed as malignant gastrointestinal neuroectodermal tumor.
[image: http:--http://ift.tt/1YyhL4R] [image: http:--http://ift.tt/1Fkw4zC] Related Articles *Esophageal subepithelial lesion diagnosed as malignant gastrointestinal neuroectodermal tumor.* World J Gastroenterol. 2015 May 14;21(18):5739-43 Authors: Kim SB, Lee SH, Gu MJ Abstract A 21-year-old male visited our hospital with a complaint of aggravating dysphagia and odynophagia for a few days. Esophagogastroduodenoscopy showed huge bulging mucosa with an intact surface causing luminal narrowing at 35 cm from the incisor teeth. Endoscopic ultrasonography showed an about 35 mm sized ... περισσότερα »
Effect of peroral esophageal myotomy for achalasia treatment: A Chinese study.
[image: http:--http://ift.tt/1YyhL4R] [image: http:--http://ift.tt/1Fkw4zC] Related Articles *Effect of peroral esophageal myotomy for achalasia treatment: A Chinese study.* World J Gastroenterol. 2015 May 14;21(18):5622-9 Authors: Lu B, Li M, Hu Y, Xu Y, Zhang S, Cai LJ Abstract AIM: To assess the safety and feasibility of peroral esophageal myotomy (POEM) in patients with achalasia. METHODS: From January 2012 to March 2014, 50 patients (28 men, 22 women; mean age: 42.8 years, range: 14-70 years) underwent POEM. Pre- and postoperative symptoms were quantified using the Eckardt s... περισσότερα »
Shorter myotomy on the gastric site (≤2.5 cm) provides adequate relief of dysphagia in achalasia patients.
[image: http:--media.wiley.com-assets-7315-19-Wi] Related Articles *Shorter myotomy on the gastric site (≤2.5 cm) provides adequate relief of dysphagia in achalasia patients.* Dis Esophagus. 2015 Jul;28(5):412-7 Authors: Salvador R, Caruso V, Costantini M, Parise P, Nicoletti L, Cavallin F, Zanatta L, Bardini R, Ancona E, Zaninotto G Abstract The right length of the myotomy on the gastric side for esophageal achalasia is still a debated issue. We aimed to investigate the final outcome after classic myotomy (CM) as compared with a longer myotomy on the gastric side (LM) in two coh... περισσότερα »
Effect of baclofen on the acid pocket at the gastroesophageal junction.
[image: http:--media.wiley.com-assets-7315-19-Wi] Related Articles *Effect of baclofen on the acid pocket at the gastroesophageal junction.* Dis Esophagus. 2015 Jul;28(5):488-95 Authors: Scarpellini E, Boecxstaens V, Farré R, Bisschops R, Dewulf D, Gasbarrini A, Pauwels A, Blondeau K, Tack J Abstract Previous studies established that a pocket of highly acidic gastric juice is present postprandially at the gastroesophageal junction in man. The GABA-B agonist baclofen inhibits postprandial reflux events through its effects on the lower esophageal sphincter (LES). The aim of the curr... περισσότερα »
The encoding of word forms into memory may be challenging for college students with developmental language impairment
10.3109/17549507.2016.1159337<br>Karla McGregor from #ENT via xlomafota13 on Inoreader http://ift.tt/1RQUVWs via IFTTT
Leukocyte-reduced platelet-rich plasma alters protein expression
of adipose-tissue derived mesenchymal stem cells.: Background: Application of platelet-rich plasma (PRP) and stem cells has become of importance in regenerative medicine. Recent literature supports the use of PRP as a cell culture media supplement to stimulate proliferation of adipose-tissue derived mesenchymal stem cells (ASCs). The underlying mechanism of proliferation stimulation by PRP has not been investigated so far. Methods: ASCs were cultured in [alpha]-MEM supplemented with PRP or fetal calf serum (FCS). Cell proliferation was assessed by means of cell cycle kinetics using...περισσότερα »
Delayed diagnosis of childhood deafness
the value of false negatives in the Programme for Early Detection of Neonatal Hearing Loss.: Acta Otorrinolaringol Esp. 2016 Apr 6; Authors: Martínez-Pacheco MC, Ferrán de la Cierva L, García-Purriños FJ Abstract INTRODUCTION: Despite its importance, the existence of false negatives (patients who are told they hear well, but they have some degree of hipacusia) is rarely evaluated in programs for early detection of hearing loss. The aim of this study is to determine the variables that can lead to a delayed diagnosis, especially the existence of false negatives and the lack of regi... περισσότερα »
Identification and Prevalence of Allergic, Nonallergic, and Local Allergic Rhinitis
Saudi Arabia: Objectives: To evaluate the diagnostic yield of skin prick test (SPT) and serum total immunoglobulin E (IgE) antibodies level in patients with allergic rhinitis (AR) and the role of nasal provocation test (NPT) for the determination of local allergic rhinitis (LAR) in patients with nonallergic rhinitis (NAR). Methodology: This multi-center study included 1230 patients with clinical manifestations for ≥2 years. Patients were classified according to the Allergic Rhinitis and Its Impact on Asthma (ARIA) and scored according to the quantitative Score for Allergic Rhinitis... περισσότερα »
Otopathologic Findings of Pena-Shokeir Syndrome Type I
Otopathologic Findings of Pena-Shokeir Syndrome Type I: Background: Pena-Shokeir syndrome type I is a rare genetic disorder that includes multiple congenital facial and joint anomalies as well as pulmonary hypoplasia. Affected infants are usually premature, and 30% of them are stillborn. So far, studies have reported low-set ears in such infants, with no middle or inner ear findings. Method: Histopathological study of human temporal bones with Pena-Shokeir syndrome type I. Results: Our case report describes an infant with severely decreased number of spiral ganglion cells and num...περισσότερα »
Idiopathic Subglottic Stenosis
A Comparison of Tracheal Size: Objective: To assess the size of the cervical and thoracic trachea among female patients with idiopathic subglottic stenosis (SGS). Methods: Computed tomography (CT) scans of neck/chest from female patients with idiopathic SGS (n = 7) and normal controls (n = 30) were analyzed. Only female patients were included. The diameter and cross-sectional area of the trachea were measured at the level of the subglottic larynx, mid-cervical trachea, and mid-thoracic trachea. Measurements of tracheal size were compared between groups. Results: Patients with idi... περισσότερα »
Detrimental health effects of benzene exposure in adults after a flaring disaster at the BP refinery plant in Texas City
Disaster Medicine and Public Health Preparedness from Emergency Medicine via xlomafota13 on Inoreader http://ift.tt/23r5C9K
A meta-analysis of percutenous compression plate versus intramedullary nail for treatment of intertrochanteric HIP fractures
International Journal of Surgery from Emergency Medicine via xlomafota13 on Inoreader http://ift.tt/1Nmguci
Characterizing Hospital Admissions to a Tertiary Care Hospital After Typhoon Haiyan
Disaster Medicine and Public Health Preparedness from Emergency Medicine via xlomafota13 on Inoreader http://ift.tt/23r5CXe
Discordance between Hemoconcentration and Clinical Assessment of Decongestion in Acute Heart Failure
Journal of Cardiac Failure from Emergency Medicine via xlomafota13 on Inoreader http://ift.tt/1Nmguc7
Saving lives and protecting people from injuries and violence
Annals of Emergency Medicine from Emergency Medicine via xlomafota13 on Inoreader http://ift.tt/23r5A1C
Nonsteroidal anti-inflammatory drug toxicity in children: a clinical review
Pediatric Emergency Care from Emergency Medicine via xlomafota13 on Inoreader http://ift.tt/1NmgtVK
Abdominal compartment syndrome in trauma patients: New insights for predicting outcomes
Journal of Emergencies, Trauma and Shock from Emergency Medicine via xlomafota13 on Inoreader http://ift.tt/23r5BCJ
Management of maxillofacial trauma in emergency: An update of challenges and controversies
Journal of Emergencies, Trauma and Shock from Emergency Medicine via xlomafota13 on Inoreader http://ift.tt/1NmgtVA
Mechanical ventilation in critical care transport
Air Medical Journal from Emergency Medicine via xlomafota13 on Inoreader http://ift.tt/23r5BCz
Effort-reward imbalance and post-traumatic stress after a workplace terror attack
Disaster Medicine and Public Health Preparedness from Emergency Medicine via xlomafota13 on Inoreader http://ift.tt/1NmgtF8
KDIGO-based acute kidney injury criteria operate differently in hospitals and the community - findings from a large population cohort
Nephrology Dialysis Transplantation from Emergency Medicine via xlomafota13 on Inoreader http://ift.tt/23r5zKX
Traumatic injuries in patients with diabetes mellitus
Journal of Emergencies, Trauma and Shock from Emergency Medicine via xlomafota13 on Inoreader http://ift.tt/1NmgtoN
Optimal dosing of IV ketamine for procedural sedation in children in the emergency department - a randomized controlled trial
The American Journal of Emergency Medicine from Emergency Medicine via xlomafota13 on Inoreader http://ift.tt/23r5B5D
When extracorporeal cardiopulmonary resuscitation fails – Fatal ionized hypocalcemia during cardiac arrest
The American Journal of Emergency Medicine from Emergency Medicine via xlomafota13 on Inoreader http://ift.tt/1NmgtoG
Diagnostic performance of initial serum lactate for predicting bacteremia in female patients with acute pyelonephritis
The American Journal of Emergency Medicine from Emergency Medicine via xlomafota13 on Inoreader http://ift.tt/23r5B5y
The association between limited english proficiency and unplanned emergency department revisit within 72 hours
Annals of Emergency Medicine from Emergency Medicine via xlomafota13 on Inoreader http://ift.tt/1Nmgrgy
A prediction model to identify patients without a concerning intra abdominal diagnosis
The American Journal of Emergency Medicine from Emergency Medicine via xlomafota13 on Inoreader http://ift.tt/23r5ze9
Injury patterns and outcomes of ice-fishing in the United States
The American Journal of Emergency Medicine from Emergency Medicine via xlomafota13 on Inoreader http://ift.tt/1Nmgrgt
Emergency physicians seek their place in a pay-for-value world
Annals of Emergency Medicine from Emergency Medicine via xlomafota13 on Inoreader http://ift.tt/23r5AOZ
A mathematical simulation of the tip-apex distance and the calcar-referenced tip-apex distance for intertrochanteric fractures reduced with lag screws
Injury from Emergency Medicine via xlomafota13 on Inoreader http://ift.tt/1NmgsRF
Trichloroacetic Acid Chemocauterization to Close Small Tracheocutaneous Fistula
Trichloroacetic Acid Chemocauterization: A Simple Method to Close Small Tracheocutaneous Fistula: Objectives: To evaluate the effectiveness of chemocauterization using trichloroacetic acid with or without suturing for the small tracheocutaneous fistula closure Methods: The Seoul National University Hospital database was analyzed retrospectively for 55 patients with a small tracheocutaneous fistula measuring less than 5 x 5 mm2. Of these, 39 patients were treated by chemocauterization only, and 16 patients were treated by chemocauterization with suturing. Demographic, perioperative ...περισσότερα »
Prognostic Value of the Pretreatment Neutrophil-to-Lymphocyte Ratio and Platelet-to-Lymphocyte Ratio for Patients with Neuroendocrine Tumors
An Izmir Oncology Group Study: *Background:* Several studies evaluating the prognostic factors of gastrointestinal and pancreatic neuroendocrine tumors (GEP-NETs) have been published. The neutrophil-lymphocyte ratio (NLR) and platelet-lymphocyte ratio (PLR) have been accepted as prognostic factors for cancer patients. *Materials and Methods:* This study included 132 patients diagnosed with GEP-NETs. Peripheral blood samples were collected before the pretreatment period. *Results:* NLR and PLR were increased as the grade increased in NETs. The embryonic origin analysis revealed high...περισσότερα »
SPAK and OSR1 play essential roles in potassium homeostasis through actions on the distal convoluted tubule
Abstract STE20 (Sterile 20)/SPS-1 related Proline/Alanine-rich Kinase (SPAK) and Oxidative Stress-Response kinase-1 (OSR1) activate the renal cation cotransporters Na+-K+-2Cl− cotransporter (NKCC2) and Na+-Cl− cotransporter (NCC) via phosphorylation. Knockout mouse models suggest that OSR1 mainly activates NKCC2, while SPAK mainly activates NCC, with possible cross-compensation. We tested the hypothesis that disrupting both kinases causes severe polyuria and salt-wasting by generating SPAK/OSR1 double knockout (DKO) mice. DKO mice displayed lower systolic blood pressure compared wi... περισσότερα »
Quantifying sympathetic neuro-haemodynamic transduction at rest in humans: Insights into sex, ageing and blood pressure control
Abstract Sex and age differences in the sympathetic control of resting blood pressure (BP) may be due to differences in the transduction of sympathetic nerve activity (SNA) into vascular tone. Current methods for dynamically quantifying transduction focus on the relationship between SNA and vasoconstriction during a pressor stimulus, which increases BP and may be contra-indicated in patients. We describe a simple analytical method for quantifying transduction under resting conditions. We performed linear regression analysis of binned muscle SNA burst areas against diastolic BP (DBP...περισσότερα »
Anaemia in patients with inflammatory bowel disease - a nationwide cross-sectional study
AlexAndros SfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026Πριν από 37 δευτερόλεπτα
Digestion from Gastroenterology via xlomafota13 on Inoreader http://ift.tt/1VjmM44 via IFTTT
Clostridium difficile infection: A model for disruption of the gut microbiota equilibrium
AlexAndros SfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026Πριν από 37 δευτερόλεπτα
Digestive Diseases from Gastroenterology via xlomafota13 on Inoreader http://ift.tt/20xASib via IFTTT
Racial and socioeconomic disparities in gastrostomy tube placement after intracerebral hemorrhage in the United States
AlexAndros SfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026Πριν από 37 δευτερόλεπτα
Stroke from Gastroenterology via xlomafota13 on Inoreader http://ift.tt/1VjmLx9 via IFTTT
Challenges and opportunities in the management of chronic hepatitis B infection
AlexAndros SfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026Πριν από 37 δευτερόλεπτα
International Journal of Infectious Diseases from Gastroenterology via xlomafota13 on Inoreader http://ift.tt/20xAQa0 via IFTTT
Association of maternal diabetes/glycosuria and pre-pregnancy body mass index with offspring indicators of non-alcoholic fatty liver disease
AlexAndros SfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026Πριν από 37 δευτερόλεπτα
BMC Pediatrics from Gastroenterology via xlomafota13 on Inoreader http://ift.tt/1VjmLx1 via IFTTT
TNF-alpha promotes lymphangiogenesis and lymphatic metastasis of gallbladder cancer through the ERK1/2/AP-1/VEGF-D pathway
AlexAndros SfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026Πριν από 37 δευτερόλεπτα
BMC Cancer from Gastroenterology via xlomafota13 on Inoreader http://ift.tt/20xAQ9O via IFTTT
Candidate HLA genes for prediction of co-trimoxazole-induced severe cutaneous reactions.
[image: http:--pt.wkhealth.com-pt-pt-core-templa] Authors: Kongpan T, Mahasirimongkol S, Konyoung P, Kanjanawart S, Chumworathayi P, Wichukchinda N, Kidkeukarun R, Preechakul S, Khunarkornsiri U, Bamrungram W, Supharatwattanakun B, Mootsikapun P, Kwangsukstid S, Denjanta S, Vannaprasaht S, Rungapiromnan W, Suwankesawong W, Tassaneeyakul W, Tassaneeyakul W Abstract BACKGROUND: Co-trimoxazole is a sulfonamide-containing antibiotic that is effective in the treatment of several infections and for prophylaxis of Pneumocystis jiroveci pneumonia. This drug has been reported as a common... περισσότερα »
Oral toxicity management in head and neck cancer patients treated with chemotherapy and radiation: Xerostomia and trismus (Part 2)
Literature review and consensus statement.: Crit Rev Oncol Hematol. 2016 ; Authors: Buglione M, Cavagnini R, Di Rosario F, Maddalo M, Vassalli L, Grisanti S, Salgarello S, Orlandi E, Bossi P, Majorana A, Gastaldi G, Berruti A, Trippa F, Nicolai P, Barasch A, Russi EG, Raber-Durlacher J, Murphy B, Magrini SM Abstract Radiotherapy alone or in combination with chemotherapy and/or surgery is a well-known radical treatment for head and neck cancer patients. Nevertheless acute side effects (such as moist desquamation, skin erythema, loss of taste, mucositis etc.) and in particular late... περισσότερα »
Vesicular Stomatitis Virus Lineages.Oscillatory dynamics and molecular evolution of interacting viruses were highly repeatable in VSV populations passaged under frequent co-infection
Repeatable Population Dynamics among Vesicular Stomatitis Virus Lineages Evolved under High Co-infection. Front Microbiol. 2016;7:370 Authors: Williams ES, Morales NM, Wasik BR, Brusic V, Whelan SP, Turner PE Abstract Parasites and hosts can experience oscillatory cycles, where the densities of these interacting species dynamically fluctuate through time. Viruses with different replication strategies can also interact to produce cyclical dynamics. Frequent cellular co-infection can select for defective-interfering particles (DIPs): "cheater" viruses with shortened genomes that interfe...περισσότερα »
Racial and socioeconomic disparities in gastrostomy tube placement after intracerebral hemorrhage in the United States
Alexandros G. SfakianakisστοNews in OtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 40 δευτερόλεπτα
Stroke from #Medicine via ola Kala on Inoreader http://ift.tt/1VjmLx9 via IFTTT
Six steps in quality intervention development (6SQuID)
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 49 δευτερόλεπτα
Improving the effectiveness of public health interventions relies as much on the attention paid to their design and feasibility as to their evaluation. Yet, compared to the vast literature on how to evaluate interventions, there is little to guide researchers or practitioners on how best to develop such interventions in practical, logical, evidence based ways […]
Severe stress following bereavement during pregnancy and risk of pregnancy loss: results from a population-based cohort study
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 49 δευτερόλεπτα
Background Previous findings on the association between stress during pregnancy and pregnancy loss are inconsistent. We aimed to estimate this association using a large prospective cohort. Methods This population-based study included all 1 303 660 clinically recognised pregnancies in Denmark between 1995 and 2008. We categorised women as exposed to severe stress if they lost […]
Development of a cross-cultural deprivation index in five European countries
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 49 δευτερόλεπτα
Background Despite a concerted policy effort in Europe, social inequalities in health are a persistent problem. Developing a standardised measure of socioeconomic level across Europe will improve the understanding of the underlying mechanisms and causes of inequalities. This will facilitate developing, implementing and assessing new and more effective policies, and will improve the comparability and […]
Hospitalisations at the end of life in four European countries: a population-based study via epidemiological surveillance networks
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 49 δευτερόλεπτα
Background There is a paucity of cross-national population-based research on hospitalisations of people at the end of life. We aimed to compare, in four European countries, the frequency, time, length of and factors associated with hospitalisations in the last 3 months of life. Methods Population-based mortality follow-back study via Sentinel Networks of general practitioners (GPs) […]
Work-family life courses and metabolic markers in mid-life: evidence from the British National Child Development Study
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 49 δευτερόλεπτα
Background Previous studies have found generally better health among those who combine employment and family responsibilities; however, most research excludes men, and relies on subjective measures of health and information on work and family activities from only 1 or 2 time points in the life course. This study investigated associations between work-family life course types […]
Nickel exposure and prevalent albuminuria and {beta}2-microglobulinuria: evidence from a population-based study
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 49 δευτερόλεπτα
Background High exposure to nickel could induce renal dysfunction in rodents and occupational workers. However, little is known about the effects of non-occupational exposure to nickel on renal health in the general population. We aimed to examine the associations of urinary nickel concentrations with albuminuria and β2-microglobulinuria in Chinese adults. Methods 2115 non-institutionalised Chinese men […]
Ethnic differences in cognitive development in the first 7 years: does maternal generational status matter?
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 49 δευτερόλεπτα
Background Differences in cognitive development have been observed across a variety of ethnic minority groups but relatively little is known about the persistence of these developmental inequalities over time or generations. Methods A repeat cross-sectional analysis assessed cognitive ability scores of children aged 3, 5 and 7 years from the longitudinal UK Millennium Cohort Study […]
Prevalence of hypertension subtypes in 2011 and the trends from 1991 to 2011 among Chinese adults
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 49 δευτερόλεπτα
Background This study aims to estimate the current prevalence and trends of hypertension subtypes among Chinese adults from 1991 to 2011. Methods We analysed the measurements of systolic and diastolic blood pressure among adults aged ≥18 years from the China Health and Nutrition Survey (CHNS) 1991–2011. The prevalence was age-adjusted to the 2010 census of […]
Accumulation of disadvantage over the life course and mortality
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 49 δευτερόλεπτα
Social inequalities in morbidity and mortality continue to be one of the highest public health concerns in times of increasing income inequalities in economically advanced countries. Compelling scientific evidence supports the notion that adverse socioeconomic circumstances determine poor health. To a large extent, respective epidemiological research is based on established indicators of people’s socioeconomic position, […]
Fit-for-work or fit-for-unemployment? Does the reassessment of disability benefit claimants using a tougher work capability assessment help people into work?
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 49 δευτερόλεπτα
Background Many governments have introduced tougher eligibility assessments for out-of-work disability benefits, to reduce rising benefit caseloads. The UK government initiated a programme in 2010 to reassess all existing disability benefit claimants using a new functional checklist. We investigated whether this policy led to more people out-of-work with long-standing health problems entering employment. Method We […]
Thyroid hormone activates Wnt/β-catenin signaling involved in adult epithelial development during intestinal remodeling in Xenopus laevis
Alexandros G. SfakianakisστοCell and Tissue Research by Alexandros G. SfakianakisΠριν από 49 δευτερόλεπτα
Abstract During amphibian intestinal remodeling, thyroid hormone (TH) induces some larval epithelial cells to dedifferentiate into adult stem cells, which newly generate the absorptive epithelium analogous to the mammalian epithelium. To clarify molecular mechanisms underlying adult epithelial development, we here focus on TH response genes that are associated with the canonical Wnt pathway. Our quantitative reverse transcription plus polymerase chain reaction and immunohistochemical analyses indicate that all of the genes examined, including β-catenin, c-Myc and secreted frizzle-...περισσότερα »
Potential of biofluid components to modify silver nanoparticle toxicity.
[image: http:--media.wiley.com-assets-7315-19-Wi] Related Articles *Potential of biofluid components to modify silver nanoparticle toxicity.* J Appl Toxicol. 2015 Jun;35(6):665-80 Authors: Murphy A, Sheehy K, Casey A, Chambers G Abstract Establishing realistic exposure scenarios is critical for cytotoxic investigation of silver nanoparticles (AgNP) in the gastrointestinal tract. This study investigated the potential interaction with and effect of biofluid components, namely cholic acid, deoxycholic acid and ursodeoxycholic acid, on AgNP toxicity. Two cell lines corresponding to o... περισσότερα »
Spontaneous CSF Rhinorrhea Our Experience.
*Spontaneous CSF Rhinorrhea Our Experience.* Indian J Otolaryngol Head Neck Surg. 2016 Mar;68(1):126-129 Authors: Sarkar A, Sharma N Abstract Cerebrospinal fluid (CSF) leak occurs due to an abnormal communication between the subarachnoid space and sinonasal tract. We reported a retrospective case series of five patients of spontaneous CSF rhinorrhea. These patients were undergone successful repair with a single transnasal endoscopic procedure. This is seen in anterior part of the cribriform plate of middle aged obese females. HRCT paranasal sinus (1 mm cuts) was an effective moda... περισσότερα »
Imaging of Cerebrospinal Fluid Leak.
*Imaging of Cerebrospinal Fluid Leak.* Semin Ultrasound CT MR. 2016 Apr;37(2):143-9 Authors: Bathla G, Moritani T Abstract A cerebrospinal fluid leak from the cranial cavity requires presence of a fistulous communication between the subarachnoid and extracranial space through the skull base. Imaging plays a crucial role in identifying and characterizing the skull base defect and evaluating coexisting pathologies that may alter surgical approach. The authors discuss the epidemiology, imaging, and management of cerebrospinal fluid leak, with particular reference to the imaging moda...περισσότερα »
Pure Endoscopic Endonasal Transsphenoidal Approach for Nonfunctioning Pituitary Adenomas in the Elderly: Surgical Outcomes and Complications in 158 Patients.
[image: http:--linkinghub.elsevier.com-ihub-imag] Related Articles *Pure Endoscopic Endonasal Transsphenoidal Approach for Nonfunctioning Pituitary Adenomas in the Elderly: Surgical Outcomes and Complications in 158 Patients.* World Neurosurg. 2015 Dec;84(6):1572-8 Authors: Zhan R, Ma Z, Wang D, Li X Abstract OBJECTIVE: To evaluate the safety and efficacy of the endoscopic endonasal transsphenoidal approach (EETA) for nonfunctioning pituitary adenoma (NFPA) in the elderly population. METHODS: We performed a retrospective review of operative cases over a 7-year period, in which 15... περισσότερα »
Foramen magnum meningioma: The midline suboccipital subtonsillar approach.
*Foramen magnum meningioma: The midline suboccipital subtonsillar approach.* Clin Neurol Neurosurg. 2016 Apr 2;145:28-34 Authors: Dobrowolski S, Ebner F, Lepski G, Tatagiba M Abstract OBJECTIVES: Foramen magnum meningiomas (FMMs) represent a technical challenge even for experienced neurosurgeons, because they grow in close contact with osteoarticular, nervous, and vascular structures that cannot be sacrificed or retracted during surgery. Our goal is to present our experience with 24 cases of surgically resected foramen magnum meningiomas used the midline suboccipital subtonsillar ... περισσότερα »
Imaging of Cerebrospinal Fluid Leak.
*Imaging of Cerebrospinal Fluid Leak.* Semin Ultrasound CT MR. 2016 Apr;37(2):143-9 Authors: Bathla G, Moritani T Abstract A cerebrospinal fluid leak from the cranial cavity requires presence of a fistulous communication between the subarachnoid and extracranial space through the skull base. Imaging plays a crucial role in identifying and characterizing the skull base defect and evaluating coexisting pathologies that may alter surgical approach. The authors discuss the epidemiology, imaging, and management of cerebrospinal fluid leak, with particular reference to the imaging moda...περισσότερα »
Relationship between the Temporal Changes in Positron-Emission-Tomography-Imaging-Based Textural Features and Pathologic Response and Survival in Esophageal Cancer Patients.
*Relationship between the Temporal Changes in Positron-Emission-Tomography-Imaging-Based Textural Features and Pathologic Response and Survival in Esophageal Cancer Patients.* Front Oncol. 2016;6:72 Authors: Yip SS, Coroller TP, Sanford NN, Mamon H, Aerts HJ, Berbeco RI Abstract PURPOSE: Although change in standardized uptake value (SUV) measures and PET-based textural features during treatment have shown promise in tumor response prediction, it is unclear which quantitative measure is the most predictive. We compared the relationship between PET-based features and pathologic res... περισσότερα »
Non-Surgical Management of Critically Compromised Airway Due to Dilatation of Interposed Colon.
*Non-Surgical Management of Critically Compromised Airway Due to Dilatation of Interposed Colon.* Tuberc Respir Dis (Seoul). 2016 Apr;79(2):98-100 Authors: Min J, Cho YJ Abstract We present a rare case of critically compromised airway secondary to a massively dilated sequestered colon conduit after several revision surgeries. A 71-year-old male patient had several operations after the diagnosis of gastric cancer. After initial treatment of pneumonia in the pulmonology department, he was transferred to the surgery department for feeding jejunostomy because of recurrent aspiration.... περισσότερα »
Variations in the Histopathologic Type of Esophageal Carcinoma Between the United States of America and India.
*Variations in the Histopathologic Type of Esophageal Carcinoma Between the United States of America and India.* Indian J Surg Oncol. 2016 Mar;7(1):52-55 Authors: Kolkman P, Stack A, McCarthy M, Kolkman M, Rao TS, Mukta S, Rajaram S, Thompson J, Are C Abstract The aim of this study was to compare the incidence of the different histopathologic types of esophageal carcinoma between the United States of American (US) and India. The Surveillance Epidemiology and End Result (SEER) database was analyzed to determine the incidence of different types of esophageal carcinoma in US. A retr... περισσότερα »
A truncated splice variant of human lysyl oxidase-like 2 promotes migration and invasion in esophageal squamous cell carcinoma.
*A truncated splice variant of human lysyl oxidase-like 2 promotes migration and invasion in esophageal squamous cell carcinoma.* Int J Biochem Cell Biol. 2016 Apr 7; Authors: Zou HY, Lv GQ, Dai LH, Zhan XH, Jiao JW, Liao LD, Zhou TM, Li CQ, Wu BL, Xu LY, Li EM Abstract Lysyl oxidase-like 2 (LOXL2) is a member of the lysyl oxidase family, which plays an important role in extracellular matrix protein biosynthesis and tumor progression. In the present study, we identified a novel splice variant, LOXL2Δ72, which encodes a peptide having the same N- and C-termini as wild-type LOXL2 (... περισσότερα »
Neuropilin-2 promotes tumorigenicity and metastasis in esophageal squamous cell carcinoma through ERK MAPK/ETV4/MMP/E-cadherin deregulation.
*Neuropilin-2 promotes tumorigenicity and metastasis in esophageal squamous cell carcinoma through ERK MAPK/ETV4/MMP/E-cadherin deregulation.* J Pathol. 2016 Apr 11; Authors: Fung TM, Ng KY, Tong M, Chen JN, Chai S, Chan KT, Law S, Lee NP, Choi MY, Li B, Cheung AL, Tsao SW, Qin YR, Guan XY, Chan KW, Ma S Abstract Esophageal squamous cell carcinoma (ESCC) is the most common histologic subtype of esophageal cancer. The disease is particularly prevalent in Southern China. The incidence of the disease is on the rise and its overall survival rate remains dismal. Identification and char... περισσότερα »
Is helical tomotherapy-based intensity-modulated radiotherapy feasible and effective in bilateral synchronous breast cancer? A two-center experience.
*Is helical tomotherapy-based intensity-modulated radiotherapy feasible and effective in bilateral synchronous breast cancer? A two-center experience.* J BUON. 2016 Jan-Mar;21(1):46-52 Authors: Ekici K, Gokce T, Karadogan I, Fatma Eraslan A, Akcay C, Temelli O, Kaya Pepele E, Durmus Manalp F, Keles C, Mayadagli A Abstract PURPOSE: This study describes the early clinical results and dosimetric parameters of intensity-modulated radiation therapy (IMRT) using a tomotherapy device in patients with primary bilateral synchronous breast cancer (PSBBC). METHODS: Fourteen patients with bil... περισσότερα »
Lipopolysaccharide-induced toll-like receptor 4 signaling in esophageal squamous cell carcinoma promotes tumor proliferation and regulates inflammatory cytokines expression.
*Lipopolysaccharide-induced toll-like receptor 4 signaling in esophageal squamous cell carcinoma promotes tumor proliferation and regulates inflammatory cytokines expression.* Dis Esophagus. 2016 Apr 7; Authors: Zu Y, Ping W, Deng T, Zhang N, Fu X, Sun W Abstract Emerging evidence suggests toll-like receptor 4 (TLR4) signaling contributes to cancer development and progression. However, the consequences of signaling via the TLR4 pathway in esophageal squamous cell carcinoma (ESCC) are still unclear. Here, we investigated the impact of Lipopolysaccharide (LPS)-induced TLR4 signalin...περισσότερα »
Two novel polymorphisms in PLCE1 are associated with the susceptibility to esophageal squamous cell carcinoma in Chinese population.
*Two novel polymorphisms in PLCE1 are associated with the susceptibility to esophageal squamous cell carcinoma in Chinese population.* Dis Esophagus. 2016 Apr 7; Authors: Qu Y, Zhang S, Cui L, Wang K, Song C, Wang P, Zhang J, Dai L Abstract Esophageal cancer is the sixth leading cause of cancer-associated death worldwide. Phospholipase C epsilon 1 (PLCE1) gene was found to be associated with the risk of esophageal squamous cell carcinoma (ESCC) by three large-scale genome-wide association studies (GWAS) in Chinese populations. To evaluate the association between the single nucleot... περισσότερα »
Phase II trial of neoadjuvant chemotherapy with docetaxel, nedaplatin, and S1 for advanced esophageal squamous cell carcinoma.
*Phase II trial of neoadjuvant chemotherapy with docetaxel, nedaplatin, and S1 for advanced esophageal squamous cell carcinoma.* Cancer Sci. 2016 Apr 7; Authors: Tanaka Y, Yoshida K, Tanahashi T, Okumura N, Matsuhashi N, Yamaguchi K Abstract Although standard chemotherapy for esophageal cancer patients is fluorouracil and cisplatin (FP), the prognosis is still unsatisfactory. A new therapeutic regimen combining docetaxel, cisplatin, and 5-Fu (DCF) was recently developed to improve both local and distant tumor control. We developed a new regimen of docetaxel, nedaplatin, and S1 (D...περισσότερα »
Potential risk factors and outcomes of fistulas between the upper intestinal tract and the airway following Ivor-Lewis esophagectomy.
*Potential risk factors and outcomes of fistulas between the upper intestinal tract and the airway following Ivor-Lewis esophagectomy.* Dis Esophagus. 2016 Apr 7; Authors: Lindner K, Lübbe L, Müller AK, Palmes D, Senninger N, Hummel R Abstract Fistulas between the upper intestinal tract and the airway following esophagectomy are a rare and severe complication with significant mortality. Treatment and therapy are difficult and require a multidisciplinary approach. The objective of this retrospective study was to identify risk factors for these fistulas following esophagetcomy, and ...περισσότερα »
Traditional serrated adenomas of the upper digestive tract.
Related Articles *Traditional serrated adenomas of the upper digestive tract.* J Clin Pathol. 2016 Jan;69(1):1-5 Authors: Rubio CA Abstract For many years, it was generally accepted that the vast majority of the colorectal carcinomas (CRCs) evolved from conventional adenomas, via the adenoma-carcinoma sequence. More recently, serrated colorectal polyps (hyperplastic polyps, sessile serrated polyps and traditional serrated adenomas (TSAs)) have emerged as an alternative pathway of colorectal carcinogenesis. It has been estimated that about 30% of the CRC progress via the serrated... περισσότερα »
Esophageal subepithelial lesion diagnosed as malignant gastrointestinal neuroectodermal tumor.
Related Articles *Esophageal subepithelial lesion diagnosed as malignant gastrointestinal neuroectodermal tumor.* World J Gastroenterol. 2015 May 14;21(18):5739-43 Authors: Kim SB, Lee SH, Gu MJ Abstract A 21-year-old male visited our hospital with a complaint of aggravating dysphagia and odynophagia for a few days. Esophagogastroduodenoscopy showed huge bulging mucosa with an intact surface causing luminal narrowing at 35 cm from the incisor teeth. Endoscopic ultrasonography showed an about 35 mm sized irregular margined in-homogenous hypoechoic lesion with an obscure layer of ... περισσότερα »
Diagnosis and surgical treatment of esophageal gastrointestinal stromal tumors.
Related Articles *Diagnosis and surgical treatment of esophageal gastrointestinal stromal tumors.* World J Gastroenterol. 2015 May 14;21(18):5630-4 Authors: Zhang FB, Shi HC, Shu YS, Shi WP, Lu SC, Zhang XY, Tu SS Abstract AIM: To retrospectively evaluate our experience with the diagnosis and surgical resection of esophageal gastrointestinal stromal tumors (GISTs). METHODS: Between January 2003 and August 2014, five esophageal GIST cases were admitted to our hospital. In this study, the hospital records, surgery outcomes, tumor recurrence and survival of these patients were retro... περισσότερα »
A phase ib study of safety and pharmacokinetics of ramucirumab in combination with paclitaxel in patients with advanced gastric adenocarcinomas.
Related Articles *A phase ib study of safety and pharmacokinetics of ramucirumab in combination with paclitaxel in patients with advanced gastric adenocarcinomas.* Oncologist. 2015 May;20(5):493-4 Authors: Ueda S, Satoh T, Gotoh M, Gao L, Doi T Abstract LESSONS LEARNED: The pharmacokinetic results of this phase Ib study of ramucirumab combined with paclitaxel as second-line therapy in Japanese patients with metastatic gastric or gastro-esophageal junction adenocarcinoma are in line with previous ramucirumab studies.This combination at the doses and schedule given did not result ... περισσότερα »
Angiogenic inhibitors in gastric cancers and gastroesophageal junction carcinomas: A critical insight.
Related Articles *Angiogenic inhibitors in gastric cancers and gastroesophageal junction carcinomas: A critical insight.* Crit Rev Oncol Hematol. 2015 Aug;95(2):165-78 Authors: Aprile G, Ongaro E, Del Re M, Lutrino SE, Bonotto M, Ferrari L, Rihawi K, Cardellino GG, Pella N, Danesi R, Fasola G Abstract Advanced gastric cancer ranks second as the global leading cause of cancer-related death and improvements in systemic chemotherapy have reached a plateau. Advanced molecular sequencing techniques help identifying patients more likely to respond to targeted agents; nevertheless we ar... περισσότερα »
Role of surgery in the management and prognosis of limited-stage small cell carcinoma of the esophagus.
Related Articles *Role of surgery in the management and prognosis of limited-stage small cell carcinoma of the esophagus.* Dis Esophagus. 2015 Jul;28(5):476-82 Authors: Xie MR, Xu SB, Sun XH, Ke L, Mei XY, Liu CQ, Ma DC Abstract Small cell carcinoma of the esophagus (SCCE) is a rare, highly aggressive tumor characterized by early dissemination and a poor prognosis. Surgery, chemotherapy, and radiotherapy have been used alone or in combination for the treatment of this rare disease. The aim of this retrospective study was to analyze the role of surgery in the management of limited... περισσότερα »
Prognostic significance of gamma-glutamyltransferase in patients with resectable esophageal squamous cell carcinoma.
Related Articles *Prognostic significance of gamma-glutamyltransferase in patients with resectable esophageal squamous cell carcinoma.* Dis Esophagus. 2015 Jul;28(5):496-504 Authors: Yang F, Zhang S, Yang H, Luo K, Wen J, Hu Y, Hu R, Huang Q, Chen J, Fu J Abstract Gamma-glutamyltransferase (GGT) is a membrane-bound enzyme involved in the glutathione metabolism. Studies suggested that GGT was a marker of apoptotic balance and modulated tumor progression, invasion and drug resistance. Recently, GGT was shown to be associated with the progression of high-grade esophageal epithelial... περισσότερα »
Shorter myotomy on the gastric site (≤2.5 cm) provides adequate relief of dysphagia in achalasia patients.
Related Articles *Shorter myotomy on the gastric site (≤2.5 cm) provides adequate relief of dysphagia in achalasia patients.* Dis Esophagus. 2015 Jul;28(5):412-7 Authors: Salvador R, Caruso V, Costantini M, Parise P, Nicoletti L, Cavallin F, Zanatta L, Bardini R, Ancona E, Zaninotto G Abstract The right length of the myotomy on the gastric side for esophageal achalasia is still a debated issue. We aimed to investigate the final outcome after classic myotomy (CM) as compared with a longer myotomy on the gastric side (LM) in two cohorts of achalasia patients. Forty-four achalasia ... περισσότερα »
Epstein-Barr Virus EBNA-2 Polymorphic Patterns in Nasopharyngeal Carcinoma in Southern China
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 56 δευτερόλεπτα
Objectives: The aim of this study was to characterize the specific Epstein-Barr virus (EBV) polymorphisms from nasopharyngeal carcinoma (NPC) patients and healthy donors in Southern China, and to explore the relationship between EBV genotypes and NPC. Methods: The EBNA-2 gene of 32 EBV-positive NPCs and 39 EBV-positive throat washing (TW) samples from healthy individuals from […]
Dysfunctional endosomes are early sign of neurodegeneration
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 56 δευτερόλεπτα
Enlarged cell structures precede hallmarks and symptoms of Alzheimer’s Disease and Down Syndrome. from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/22r3xVB via IFTTT
Same immune-system proteins may first giveth, then taketh away motor control
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 56 δευτερόλεπτα
Princeton University researchers have found that a family of proteins with important roles in the immune system may be responsible for fine-tuning a person’s motor control as they grow — and for… from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1Wpe2ci via IFTTT
Concussion can alter parent-child relationships
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 56 δευτερόλεπτα
Parents should watch for emotional and behavioural changes in their children. from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/22r3xVx via IFTTT
Biologists discover new strategy to treat central nervous system injury
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 56 δευτερόλεπτα
Neurobiologists at UC San Diego have discovered how signals that orchestrate the construction of the nervous system also influence recovery after traumatic injury. from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1Wpe4ky via IFTTT
Researchers identify tissue biomarker for dementia with lewy bodies and Parkinson’s disease
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 56 δευτερόλεπτα
Accurate diagnosis of Parkinson’s disease, and the related disease «dementia with Lewy bodies,» can be difficult in the early stages of both conditions. from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/22r3xVt via IFTTT
Pain Control in the Presence of Drug Addiction
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 56 δευτερόλεπτα
Abstract Drug addiction is present in a significant proportion of the population in the USA and worldwide. Drug addiction can occur with the abuse of many types of substances including cocaine, marijuana, stimulants, alcohol, opioids, and tranquilizers. There is a high likelihood that clinicians will encounter patients with substance abuse disorders on a regular basis […]
Viruses, Vol. 8, Pages 96: Current Approaches for Diagnosis of Influenza Virus Infections in Humans
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 56 δευτερόλεπτα
Despite significant advancement in vaccine and virus research, influenza continues to be a major public health concern. Each year in the United States of America, influenza viruses are responsible for seasonal epidemics resulting in over 200,000 hospitalizations and 30,000–50,000 deaths. Accurate and early diagnosis of influenza viral infections are critical for rapid initiation of antiviral […]
Viruses, Vol. 8, Pages 95: Viral Evasion of Natural Killer Cell Activation
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 56 δευτερόλεπτα
Natural killer (NK) cells play a key role in antiviral innate defenses because of their abilities to kill infected cells and secrete regulatory cytokines. Additionally, NK cells exhibit adaptive memory-like antigen-specific responses, which represent a novel antiviral NK cell defense mechanism. Viruses have evolved various strategies to evade the recognition and destruction by NK cells […]
Subscription Page
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 56 δευτερόλεπτα
from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1SKV3TO via IFTTT
Effectiveness of chemotherapy in advanced differentiated thyroid cancer: a systematic review.
*Effectiveness of chemotherapy in advanced differentiated thyroid cancer: a systematic review.* Endocr Relat Cancer. 2016 Feb;23(2):R71-84 Authors: Albero A, Lopéz JE, Torres A, de la Cruz L, Martín T Abstract In differentiated thyroid carcinoma refractory to radioactive iodine (CDT-RTI), chemotherapy has been considered for decades to be the only systemic therapy with palliative purpose. Phase II studies assessing the efficacy of different chemotherapy outlines have been published. Nevertheless, phase III studies in these tumours have not been performed. Our objective is to eval... περισσότερα »
Cervical Paraganglioma Mimicking Thyroid Nodule: A Rare Clinical Case.
*Cervical Paraganglioma Mimicking Thyroid Nodule: A Rare Clinical Case.* Case Rep Endocrinol. 2016;2016:8527279 Authors: Aydoğan Bİ, Dizbay Sak S, Güllü S Abstract Objective. Paraganglioma is a rare neuroendocrine tumor. When it is located in the neck, it is commonly misdiagnosed as other thyroid neoplasms. Case Report. We report a case of cervical paraganglioma in a 55-year-old female. Patient was admitted to our clinic with goiter and neck pain. Thyroid ultrasonography revealed a 20 mm solitary, heterogeneous nodule located in the upper pole of left thyroid lobe. Fine needle asp...περισσότερα »
Isolated Metastasis in Male Breast from Differentiated Thyroid Carcinoma - Oncological Curiosity. A Case Report and Review of Literature.
*Isolated Metastasis in Male Breast from Differentiated Thyroid Carcinoma - Oncological Curiosity. A Case Report and Review of Literature.* Indian J Surg Oncol. 2016 Mar;7(1):91-94 Authors: Parasuraman L, Kane SV, Pai PS, Shanghvi K Abstract Papillary carcinomas are the most common thyroid malignancy accounting for approximately 80 % of thyroid cancers (Rosenbaum and McHenry Expert Rev Anticancer Ther 9:317-329, 2009). They generally manifest as solitary nodules in the thyroid with or without cervical lymphadenopathy. Distant metastases though rare, are commonly seen in lungs and ... περισσότερα »
MicroRNA-1280 modulates cell growth and invasion of thyroid carcinoma through targeting estrogen receptor α.
*MicroRNA-1280 modulates cell growth and invasion of thyroid carcinoma through targeting estrogen receptor α.* Cell Mol Biol (Noisy-le-grand). 2016;62(3):1-6 Authors: Meng D, Li Z, Ma X, Fu L, Qin G Abstract Thyroid cancer (TC) is one of the most common endocrine malignancies, with a steadily increasing incidence and lethality over the last several decades. ERα is a nuclear hormone receptor that has a key role in different cellular process and participates in the development and progression of thyroid cancer. ERα is the predicted target gene of microRNA-1280 (miR-1280). The prese... περισσότερα »
Effectiveness of chemotherapy in advanced differentiated thyroid cancer: a systematic review.
*Effectiveness of chemotherapy in advanced differentiated thyroid cancer: a systematic review.* Endocr Relat Cancer. 2016 Feb;23(2):R71-84 Authors: Albero A, Lopéz JE, Torres A, de la Cruz L, Martín T Abstract In differentiated thyroid carcinoma refractory to radioactive iodine (CDT-RTI), chemotherapy has been considered for decades to be the only systemic therapy with palliative purpose. Phase II studies assessing the efficacy of different chemotherapy outlines have been published. Nevertheless, phase III studies in these tumours have not been performed. Our objective is to eval... περισσότερα »
Incidence of Permanent Hypocalcaemia after Total Thyroidectomy with or without Central Neck Dissection for Thyroid Carcinoma: A Nationwide Claim Study.
*Incidence of Permanent Hypocalcaemia after Total Thyroidectomy with or without Central Neck Dissection for Thyroid Carcinoma: A Nationwide Claim Study.* Clin Endocrinol (Oxf). 2016 Apr 11; Authors: Seo GH, Chai YJ, Choi HJ, Lee KE Abstract OBJECTIVE: Permanent hypocalcaemia is the most common and serious complication after total thyroidectomy (TT). This study examined the impact of central neck dissection (CND) and institutional volume on rates of permanent hypocalcaemia by analysing data held in the nationwide claim database of South Korea. DESIGN: Data from patients who underw... περισσότερα »
Extent of lymph node dissection in papillary thyroid cancer.
*Extent of lymph node dissection in papillary thyroid cancer.* Surgery. 2016 Apr 7; Authors: Sindoni A, Fama' F PMID: 27063342 [PubMed - as supplied by publisher] from pubmed: thyroid cancer http://ift.tt/1SKUsla via IFTTT
Post-adjuvant chemotherapy for triple-negative breast cancer.
*Post-adjuvant chemotherapy for triple-negative breast cancer.* Med Hypotheses. 2016 May;90:74-5 Authors: Sun S, Zhao Y, Xu K PMID: 27063090 [PubMed - in process] from pubmed: thyroid cancer http://ift.tt/1VlatoD via IFTTT
Microrna-199a-5p Functions as a Tumor Suppressor via Suppressing Connective Tissue Growth Factor (CTGF) in Follicular Thyroid Carcinoma.
*Microrna-199a-5p Functions as a Tumor Suppressor via Suppressing Connective Tissue Growth Factor (CTGF) in Follicular Thyroid Carcinoma.* Med Sci Monit. 2016;22:1210-2117 Authors: Sun D, Han S, Liu C, Zhou R, Sun W, Zhang Z, Qu J Abstract BACKGROUND The objective of this study was to explore the role of miR-199a-5p in the development of thyroid cancer, including its anti-proliferation effect and downstream signaling pathway. MATERIAL AND METHODS We conducted qRT-PCR analysis to detect the expressions of several microRNAs in 42 follicular thyroid carcinoma patients and 42 controls... περισσότερα »
Clinical outcomes of patients with hypercalcitoninemia after initial treatment for medullary thyroid cancer and postoperative serum calcitonin cutoffs for predicting structural recurrence.
*Clinical outcomes of patients with hypercalcitoninemia after initial treatment for medullary thyroid cancer and postoperative serum calcitonin cutoffs for predicting structural recurrence.* Head Neck. 2016 Apr 7; Authors: Cho YY, Jang HW, Jang JY, Kim TH, Choe JH, Kim JH, Kim JS, Kim SW, Chung JH Abstract BACKGROUND: Persistent hypercalcitoninemia is reported in 40% to 60% of patients with medullary thyroid cancer (MTC) after initial therapy, but their clinical outcomes have not been clearly studied. We evaluated the outcomes of MTC with hypercalcitoninemia and assessed the cuto...περισσότερα »
Polymorphisms within base and nucleotide excision repair pathways and risk of differentiated thyroid carcinoma.
*Polymorphisms within base and nucleotide excision repair pathways and risk of differentiated thyroid carcinoma.* DNA Repair (Amst). 2016 Mar 31;41:27-31 Authors: Cipollini M, Figlioli G, Maccari G, Garritano S, De Santi C, Melaiu O, Barone E, Bambi F, Ermini S, Pellegrini G, Cristaudo A, Foddis R, Bonotti A, Romei C, Vivaldi A, Agate L, Molinari E, Barale R, Forsti A, Hemminki K, Elisei R, Gemignani F, Landi S Abstract The thyrocytes are exposed to high levels of oxidative stress which could induce DNA damages. Base excision repair (BER) is one of the principal mechanisms of def...περισσότερα »
Antitumor effect of CXCR4 antagonist AMD3100 on the tumorigenic cell line of BHP10-3 papillary thyroid cancer cells.
*Antitumor effect of CXCR4 antagonist AMD3100 on the tumorigenic cell line of BHP10-3 papillary thyroid cancer cells.* Head Neck. 2016 Apr 7; Authors: Jung YH, Lee DY, Cha W, Kim BH, Sung MW, Kim KH, Ahn SH Abstract BACKGROUND: A tumorigenic cell line (BHP10-3M) derived from nontumorigenic papillary thyroid carcinoma (PTC) cells (BHP10-3) having rearranged during transfection (RET)/PTC1 gene rearrangement might have a higher expression of CXCR4, either quantitatively or functionally. The authors also postulated that CXCR4-mediated invasion or tumorigenesis could be blocked by CXC... περισσότερα »
Expression of sodium iodide symporter in human breast tissues.
*Expression of sodium iodide symporter in human breast tissues.* J BUON. 2016 Jan-Mar;21(1):53-60 Authors: Angelousi A, Nonni A, Kassi E, Kontzoglou K Abstract PURPOSE: Sodium iodide symporter (NIS) expression in breast cancer (BC) tissues suggests the possibility of using radioiodine for diagnostic and therapeutic purposes. This study evaluated NIS protein expression in primary BC samples and its association with BC prognostic markers and thyroid functional parameters. METHODS: Fifty-six breast tissue samples from 52 operated women (41 BC, 11 benign breast diseases (BBD) and 4 pe... περισσότερα »
Cytotechnologist Performance for Screening Hürthle Cell Atypia in Indeterminate Thyroid Fine-Needle Aspirates.
Related Articles *Cytotechnologist Performance for Screening Hürthle Cell Atypia in Indeterminate Thyroid Fine-Needle Aspirates.* Acta Cytol. 2015;59(5):377-83 Authors: VandenBussche CJ, Adams C, Ali SZ, Olson MT Abstract OBJECTIVES: We have previously shown that specimens diagnosed as containing Hürthle cells have a 12% chance of being malignant if they are classified as atypia of undetermined significance (AUS-HC). The identification of Hürthle cells by cytotechnologists (CTs) during screening can improve cytopathologist efficiency and may prevent diagnostic errors due to the ... περισσότερα »
Cytologic Features and Immunocytochemical Profiles of Malignant Effusions with Metastatic Papillary Thyroid Carcinoma: A Case Series from a Single Institution.
Related Articles *Cytologic Features and Immunocytochemical Profiles of Malignant Effusions with Metastatic Papillary Thyroid Carcinoma: A Case Series from a Single Institution.* Acta Cytol. 2015;59(5):412-7 Authors: Lew M, Pang JC, Roh MH, Jing X Abstract OBJECTIVE: Malignant effusions due to papillary thyroid carcinoma (PTC) are rare, but portend a poor prognosis. PTC metastases, although rare, most frequently occur in the lungs and bone. Therefore, differentiating thyroid etiology of malignant effusions from other sites becomes clinically significant in patient management. Th... περισσότερα »
IJMS, Vol. 17, Pages 469: Redox Proteomic Profiling of Specifically Carbonylated Proteins in the Serum of Triple Transg enic Alzheimer’s Disease Mice
Oxidative stress is a key event in the onset and progression of neurodegenerative diseases, including Alzheimer’s disease (AD). To investigate the role of oxidative stress in AD and to search for potential biomarkers in peripheral blood, serums were collected in this study from the 3-, 6-, and 12-month-old triple transgenic AD mice (3×Tg-AD mice) and… Continue reading IJMS, Vol. 17, Pages 469: Redox Proteomic Profiling of Specifically Carbonylated Proteins in the Serum of Triple Transg enic Alzheimer’s Disease Mice
IJMS, Vol. 17, Pages 547: SAAMBE: Webserver to Predict the Charge of Binding Free Energy Caused by Amino Acids Mutations
Predicting the effect of amino acid substitutions on protein–protein affinity (typically evaluated via the change of protein binding free energy) is important for both understanding the disease-causing mechanism of missense mutations and guiding protein engineering. In addition, researchers are also interested in understanding which energy components are mostly affected by the mutation and how the… Continue reading IJMS, Vol. 17, Pages 547: SAAMBE: Webserver to Predict the Charge of Binding Free Energy Caused by Amino Acids Mutations
Scientist discovers positive correlation between HPV Disease & Cancer – Miami Daily Science – Daily Star Gazette
Scientist discovers positive correlation between HPV Disease & Cancer – Miami Daily Science Daily Star Gazette A rising proportion of these cancers are oropharyngeal cancers (cancers of the middle part of the throat including the soft palate, the base of the tongue and the tonsils). This study is the first to demonstrate conclusively that HPV-16’s… Continue reading Scientist discovers positive correlation between HPV Disease & Cancer – Miami Daily Science – Daily Star Gazette
Viruses, Vol. 8, Pages 96: Current Approaches for Diagnosis of Influenza Virus Infections in Humans
Despite significant advancement in vaccine and virus research, influenza continues to be a major public health concern. Each year in the United States of America, influenza viruses are responsible for seasonal epidemics resulting in over 200,000 hospitalizations and 30,000–50,000 deaths. Accurate and early diagnosis of influenza viral infections are critical for rapid initiation of antiviral… Continue reading Viruses, Vol. 8, Pages 96: Current Approaches for Diagnosis of Influenza Virus Infections in Humans
Viruses, Vol. 8, Pages 95: Viral Evasion of Natural Killer Cell Activation
Natural killer (NK) cells play a key role in antiviral innate defenses because of their abilities to kill infected cells and secrete regulatory cytokines. Additionally, NK cells exhibit adaptive memory-like antigen-specific responses, which represent a novel antiviral NK cell defense mechanism. Viruses have evolved various strategies to evade the recognition and destruction by NK cells… Continue reading Viruses, Vol. 8, Pages 95: Viral Evasion of Natural Killer Cell Activation
Fehlerquellen für operationsbedingte Harnleiterverletzungen
Risikomanagement Harnleiter sind bei operativen Eingriffen im kleinen Becken besonders verletzungsgefährdet. Oft steht der Vorwurf eines Behandlungsfehlers im Raum. Die Betrachtung der Begutachtungsverfahren der letzten Jahre zeigt die häufigsten Fallstricke auf. from #Medicine-Sfakianakis via simeraentaxei on Inoreader http://ift.tt/23r2FGf via IFTTT
VegMed: «VegMed – Scientific Congress for Vegetarian Nutrition and Medicine», Berlin, 22.-24. April 2016: Abstracts
Forsch Komplementmed 2016;23(suppl 1):1-13 from #Medicine-Sfakianakis via simeraentaxei on Inoreader http://ift.tt/1S2NIzk via IFTTT
Posttransurethral Resection of Prostate Recurrent Life Threatening Hematuria: A Rare Cause
Herein, we present a case report of post-TURP (transurethral resection of prostate) recurrent severe hematuria due to right internal iliac artery pseudoaneurysm protruding into bladder lumen. A 60-year-old male presented with recurrent massive hematuria following TURP done elsewhere 15 days before. His hemoglobin was 4 gm/dL after 13 units of blood transfusion and repeated clot evacuations.… Continue reading Posttransurethral Resection of Prostate Recurrent Life Threatening Hematuria: A Rare Cause
Characterization of the Physiological Response following In Vivo Administration of Astragalus membranaceus
The botanical, Astragalus membranaceus, is a therapeutic in traditional Chinese medicine. Limited literature exists on the overall in vivo effects of A. membranaceus on the human body. This study evaluates the physiological responses to A. membranaceus by measuring leukocyte, platelet, and cytokine responses as well as body temperature and blood pressure in healthy individuals after… Continue reading Characterization of the Physiological Response following In Vivo Administration of Astragalus membranaceus
Exact Boundary Controllability for Free Traffic Flow with Lipschitz Continuous State
We consider traffic flow governed by the LWR model. We show that a Lipschitz continuous initial density with free-flow and sufficiently small Lipschitz constant can be controlled exactly to an arbitrary constant free-flow density in finite time by a piecewise linear boundary control function that controls the density at the inflow boundary if the outflow… Continue reading Exact Boundary Controllability for Free Traffic Flow with Lipschitz Continuous State
Dural Venous System in the Cavernous Sinus: A Literature Review and Embryological, Functional, and Endovascular Clinical Considerations.
*Dural Venous System in the Cavernous Sinus: A Literature Review and Embryological, Functional, and Endovascular Clinical Considerations.* Neurol Med Chir (Tokyo). 2016 Apr 11; Authors: Mitsuhashi Y, Hayasaki K, Kawakami T, Nagata T, Kaneshiro Y, Umaba R, Ohata K Abstract The cavernous sinus (CS) is one of the cranial dural venous sinuses. It differs from other dural sinuses due to its many afferent and efferent venous connections with adjacent structures. It is important to know well about its complex venous anatomy to conduct safe and effective endovascular interventions for th... περισσότερα »
Training for skull base surgery by using a colored temporal bone model created by three-dimensional printing technology.
*Training for skull base surgery by using a colored temporal bone model created by three-dimensional printing technology.* World Neurosurg. 2016 Apr 5; Authors: Wanibuchi M, Noshiro S, Sugino T, Akiyama Y, Mikami T, Iihoshi S, Miyata K, Komatsu K, Mikuni N PMID: 27062915 [PubMed - as supplied by publisher] from #ENT-PubMed via ola Kala on Inoreader http://ift.tt/1Vju7Re via IFTTT
Predictors of functional outcome following treatment of posterior fossa arteriovenous malformations.
[image: http:--linkinghub.elsevier.com-ihub-imag] Related Articles *Predictors of functional outcome following treatment of posterior fossa arteriovenous malformations.* J Clin Neurosci. 2015 Feb;22(2):357-62 Authors: Yang W, Wang JY, Caplan JM, Braileanu M, Shang H, Upadhyay U, Zenonos GA, Rigamonti D, Colby GP, Coon AL, Tamargo RJ, Huang J Abstract Posterior fossa arteriovenous malformations (AVM) present particular therapeutic challenges. Studies aimed at clarifying risk of hemorrhage focus on obliteration rates, but few have addressed functional outcomes in these patients. In... περισσότερα »
Tremor in dystonia.
*Tremor in dystonia.* Parkinsonism Relat Disord. 2016 Apr 1; Authors: Pandey S, Sarma N Abstract Tremor has been recognized as an important clinical feature in dystonia. Tremor in dystonia may occur in the body part affected by dystonia known as dystonic tremor or unaffected body regions known as tremor associated with dystonia. The most common type of tremor seen in dystonia patients is postural and kinetic which may be mistaken for familial essential tremor. Similarly familial essential tremor patients may have associated dystonia leading to diagnostic uncertainties. The pathog...περισσότερα »
Δεν υπάρχουν σχόλια:
Δημοσίευση σχολίου