Journal of Allergy and Clinical Immunology
Indoor microbial communities: Influence on asthma severity in atopic and nonatopic children Publication date: Available online 4 February 2016 *Source:*Journal of Allergy and Clinical Immunology Author(s): Karen C. Dannemiller, Janneane F. Gent, Brian P. Leaderer, Jordan Peccia Background Allergic and nonallergic asthma severity in children can be affected by microbial exposures. Objective We sought to examine associations between exposures to household microbes and childhood asthma severity stratified by atopic status. Methods Participants (n = 196) were selected from a cohort of ...περισσότερα »
Complications of bariatric surgery: presentation and emergency management
International Journal of Surgery from Emergency Medicine via ola Kala on Inoreader http://ift.tt/20qkNJz via IFTTT
Pre-packing of cost effective antibiotic cement beads for the treatment of traumatic osteomyelitis in the developing world–an in-vitro study based in Cambodia
Injury from Emergency Medicine via ola Kala on Inoreader http://ift.tt/1RsxqmN via IFTTT
Unintentional childhood injury: a controlled comparison of behavioral characteristics
BMC Pharmacology & Toxicology from Emergency Medicine via ola Kala on Inoreader http://ift.tt/20qkMFr via IFTTT
Topical application of epidermal growth factor with no scaffold material on the healing of human traumatic tympanic membrane perforations
Clinical Otolaryngology from Emergency Medicine via ola Kala on Inoreader http://ift.tt/20qkMFp via IFTTT
Development of a systematic protocol to identify victims of non-accidental trauma
Pediatric Surgery International from Emergency Medicine via ola Kala on Inoreader http://ift.tt/1Rsxq6e via IFTTT
Validation of Victoria Symptom Validity Test cutoff scores among mild traumatic brain injury litigants using a known-groups design
Archives of Clinical Neuropsychology from Emergency Medicine via ola Kala on Inoreader http://ift.tt/20qkNsZ via IFTTT
Injury to the conduction system: Management of life-threatening arrthythmias after penetrating cardiac trauma
The American Journal of Surgery from Emergency Medicine via ola Kala on Inoreader http://ift.tt/1RsxsLD via IFTTT
Ultrasound-guided “short” midline catheters for difficult venous access in the emergency department: a retrospective analysis
International Journal of Emergency Medicine from Emergency Medicine via ola Kala on Inoreader http://ift.tt/20qkM8o via IFTTT
Impacted sharp oesophageal foreign bodies — a novel technique of removal with the paediatric bronchoscope
Journal of Tropical Pediatrics from Emergency Medicine via ola Kala on Inoreader http://ift.tt/1RsxsLp via IFTTT
Higher insulin resistance level is associated with worse clinical response in acute ischemic stroke patients treated with intravenous thrombolysis
Translational Stroke Research from Emergency Medicine via ola Kala on Inoreader http://ift.tt/20qkLBm via IFTTT
Unifocal versus multifocal mandibular fractures and injury location
Emergency Radiology from Emergency Medicine via ola Kala on Inoreader http://ift.tt/1RsxsuQ via IFTTT
Derivation and validation of a quality indicator to benchmark in-hospital complications among injury admissions
JAMA Surgery from Emergency Medicine via ola Kala on Inoreader http://ift.tt/20qkLBc via IFTTT
A new formula for assessing skeletal age in growing infants and children by measuring carpals and epiphyses of radio and ulna
Journal of Forensic and Legal Medicine from Emergency Medicine via ola Kala on Inoreader http://ift.tt/1RsxmDB via IFTTT
A decade of burn unit experience with Stevens-Johnson Syndrome/Toxic Epidermal Necrolysis: Clinical pathological diagnosis and risk factor awareness
Burns from Emergency Medicine via ola Kala on Inoreader http://ift.tt/20qkK05 via IFTTT
Novel burn device for rapid, reproducible burn wound generation
Burns from Emergency Medicine via ola Kala on Inoreader http://ift.tt/1Rsxmna via IFTTT
Acute liver injury and acute liver failure from mushroom poisoning in North America
Liver International from Emergency Medicine via ola Kala on Inoreader http://ift.tt/20qkLkH via IFTTT
Cellular and molecular mechanisms of AKI
Journal of the American Society of Nephrology from Emergency Medicine via ola Kala on Inoreader http://ift.tt/1Rsxm6E via IFTTT
Indoor microbial communities: Influence on asthma severity in atopic and nonatopic children
Indoor microbial communities: Influence on asthma severity in atopic and nonatopic children Publication date: Available online February 2016 *Source:*Journal of Allergy and Clinical Immunology Author(s): Karen C. Dannemiller, Janneane F. Gent, Brian P. Leaderer, Jordan Peccia Background Allergic and nonallergic asthma severity in children can be affected by microbial exposures. Objective We sought to examine associations between exposures to household microbes and childhood asthma severity stratified by atopic status. Methods Participants (n = 196) were selected from a cohort of a...περισσότερα »
Montelukast-induced metamorphopsia in a pediatric patient
Montelukast-induced metamorphopsia in a pediatric patient: Metamorphopsia is a type of optical illusion in which the size, shape, or angulation of objects is perceived as altered. Individuals typically see lines as wavy instead of straight and flat surfaces as curved. It is a rare manifestation of a central nervous system insult, mainly to the visual or vestibular systems.1 It is a symptom caused by disorders of the retina or choroid and frequently observed in age-related macular degeneration.1
Polyomavirus-Associated Nephropathy.
Predominant Tubular Interleukin-18 Expression in Polyomavirus-Associated Nephropathy.: Polyomavirus-associated nephropathy (PVAN) occurs in a significant percentage of renal transplant recipients, with BK virus reactivation as the main causative agent. PVAN leads to tubular damage and may result in allograft loss. In this study, we analyzed the antiviral immune response in PVAN. Transcription of the proinflammatory cytokine interleukin-18 (IL-18) was significantly higher in PVAN biopsies compared with T cell-mediated rejection (TCMR) (1.42 +/- 0.20 and 0.69 +/- 0.10, respectively; *...περισσότερα »
Prophylactic vaccines are potent activators of monocyte-derived dendritic cells and drive effective anti-tumor responses in melanoma patients at the cost of toxicity
Prophylactic vaccines are potent activators of monocyte-derived dendritic cells and drive effective anti-tumor responses in melanoma patients at the cost of toxicity: AbstractDendritic cell (DC)-based immunotherapy is explored worldwide in cancer patients, predominantly with DC matured with pro-inflammatory cytokines and prostaglandin E2. We studied the safety and efficacy of vaccination with monocyte-derived DC matured with a cocktail of prophylactic vaccines that contain clinical-grade Toll-like receptor ligands (BCG, Typhim, Act-HIB) and prostaglandin E2 (VAC-DC). Stage III and ... περισσότερα »
Molecular Typing Characteristic and Drug Susceptibility Analysis of Mycobacterium tuberculosis Isolates from Zigong, China
China is one of the 22 countries with high TB burden worldwide, and Sichuan contained the second-largest number of TB cases among all of the Chinese provinces. But the characteristics of Mycobacterium tuberculosis circulated in Zigong, Sichuan, were still unknown. To investigate the character and drug resistance profile, 265 clinical isolates were cultured from tuberculosis patient's sputum samples in the year of 2010, of which the genetic profile was determined by using Spoligotyping and MIRU-VNTR typing methods, and the drug sensibility testing to the four first-line and four se...περισσότερα »
Epidemic Profile of Maternal Syphilis in China in 2013
Objective. The aim of this study was to investigate the epidemiological characteristics and adverse pregnancy outcomes of pregnant women with syphilis infection in China. Methods. Data were from China's Information System of Prevention of Mother-to-Child Transmission of Syphilis Management. Women who were registered in the system and delivered in 2013 were included in the analysis. Results. A total of 15884 pregnant women with syphilis infection delivered in China in 2013. 79.1% of infected women attended antenatal care at or before 37 gestational weeks; however, 55.4% received no...περισσότερα »
Substance P Receptor Signaling Mediates Doxorubicin-Induced Cardiomyocyte Apoptosis and Triple-Negative Breast Cancer Chemoresistance
Doxorubicin (DOX), an anthracycline, is broadly considered the most active single agent available for treating breast cancer but has been known to induce cardiotoxicity. Although DOX is highly effective in treating triple-negative breast cancer (TNBC), DOX can have poor outcomes owing to induction of chemoresistance. There is an urgent need to develop new therapies for TNBC aimed at improving DOX outcome and DOX-induced cardiotoxicity. Substance P (SP), a neuropeptide involved in pain transmission is known to stimulate production of reactive oxygen species (ROS). Elevated cardiac ...περισσότερα »
Preparation of Cytokine-activated NK Cells for Use in Adoptive Cell Therapy in Cancer Patients: Protocol Optimization and Therapeutic Potential
Alexandros G. SfakianakisστοHead,Neck,Brain,Cervical Spine and Esophageal Cancers by Alexandros G. SfakianakisΠριν από 8 δευτερόλεπτα
Preparation of Cytokine-activated NK Cells for Use in Adoptive Cell Therapy in Cancer Patients: Protocol Optimization and Therapeutic Potential: Cell-based immunotherapy using donor-derived natural killer (NK) cells after allogeneic hematopoietic stem cell transplantation may be an attractive treatment of residual leukemia. This study aimed to optimize clinical grade production of a cytokine-activated NK-cell product. NK cells were isolated either by double depletion (CD3−, CD19−) or by sequential depletion and enrichment (CD3−, CD56+) via CliniMACS from leukapheresis material and c... περισσότερα »
Confocal Micro-endoscopy in Head and Neck Cancer/Micro Endoscopie Confocale (MEC)Oto-Rhino-Laryngologie (ORL)
Alexandros G. SfakianakisστοHead,Neck,Brain,Cervical Spine and Esophageal Cancers by Alexandros G. SfakianakisΠριν από 8 δευτερόλεπτα
Confocal Micro-endoscopy in Head and Neck Cancer/Micro Endoscopie Confocale (MEC)Oto-Rhino-Laryngologie (ORL): *Conditions*: Malignant Pharyngo Laryngeal Tumors; Pre-malignant Pharyngo Laryngeal Tumors *Intervention*: Procedure: Confocal Micro Endoscopy *Sponsors*: Gustave Roussy, Cancer Campus, Grand Paris; Ministry of Health, France The primary objective is to validate the diagnostic correlation between the intraoperative microendoscopic images and the conventional histological analysis on biopsy and/or surgical specimens on patients with epidermoid carcinoma. Condi...περισσότερα »
Temsirolimus and Cetuximab in Patients With Advanced or Metastatic Solid Tumors
Alexandros G. SfakianakisστοHead,Neck,Brain,Cervical Spine and Esophageal Cancers by Alexandros G. SfakianakisΠριν από 8 δευτερόλεπτα
Temsirolimus and Cetuximab in Patients With Advanced or Metastatic Solid Tumors: *Condition*: Patients With Advanced or Metastatic Solid Tumors *Interventions*: Drug: Cetuximab; Drug: Temsirolimus *Sponsor*: Gustave Roussy, Cancer Campus, Grand Paris Cetuximab is an EGFR inhibitor that has shown efficacy alone or in combination in colorectal cancer or head and neck cancer in several phase II/III studies. Temsirolimus is a new mTOR inhibitor that has shown interesting results in several Phase I/II studies in advance kidney cancer of bad prognosis. Study hypothesis is that co... περισσότερα »
Defining the medial-lateral axis of an anatomical femur coordinate system using freehand 3D ultrasound imaging
Publication date: Available online 10 February 2016 *Source:*Gait & Posture Author(s): Elyse Passmore, Morgan Sangeux Hip rotation from gait analysis informs clinical decisions regarding correct of femoral torsional deformities. However, it is among the least repeatable due to discrepancies in determining the medial-lateral axis of the femur. Conventional or functional calibration methods may be used to define the axis but there is no benchmark to evaluate these methods. Freehand 3D ultrasound, the coupling of ultrasound with 3D motion capture, may provide such a benchmark.We measur... περισσότερα »
Age-independent and age-dependent sex differences in gait pattern determined by principal component analysis
Publication date: Available online 11 February 2016 *Source:*Gait & Posture Author(s): Yoshiyuki Kobayashi, Hiroaki Hobara, Thijs A. Heldoorn, Makiko Kouchi, Masaaki Mochimaru Although various studies have reported significant sex differences in pelvic and/or hip-joint motion during normal walking in healthy adults, it is still unclear whether such differences are among the most dominant age-independent sex differences. This study was conducted to analyze the whole waveform of lower-extremity joint kinematics obtained from 191 healthy adults using a 1212□principal component analysis...περισσότερα »
Whole-brain grey matter density predicts balance stability irrespective of age and protects older adults from falling
Publication date: March 2016 *Source:*Gait & Posture, Volume 45 Author(s): Matthieu P. Boisgontier, Boris Cheval, Peter van Ruitenbeek, Oron Levin, Olivier Renaud, Julien Chanal, Stephan P. Swinnen Functional and structural imaging studies have demonstrated the involvement of the brain in balance control. Nevertheless, how decisive grey matter density and white matter microstructural organisation are in predicting balance stability, and especially when linked to the effects of ageing, remains unclear. Standing balance was tested on a platform moving at different frequencies and ampl...περισσότερα »
Identification of trunk and pelvis movement compensations in patients with transtibial amputation using angular momentum separation
Publication date: March 2016 *Source:*Gait & Posture, Volume 45 Author(s): Brecca M. Gaffney, Amanda M. Murray, Cory L. Christiansen, Bradley S. Davidson Patients with unilateral dysvascular transtibial amputation (TTA) have a higher risk of developing low back pain than their healthy counterparts, which may be related to movement compensations used in the absence of ankle function. Assessing components of segmental angular momentum provides a unique framework to identify and interpret these movement compensations alongside traditional observational analyses. Angular momentum separa... περισσότερα »
Defining the medial-lateral axis of an anatomical femur coordinate system using freehand 3D ultrasound imaging
Publication date: Available online 10 February 2016 *Source:*Gait & Posture Author(s): Elyse Passmore, Morgan Sangeux Hip rotation from gait analysis informs clinical decisions regarding correct of femoral torsional deformities. However, it is among the least repeatable due to discrepancies in determining the medial-lateral axis of the femur. Conventional or functional calibration methods may be used to define the axis but there is no benchmark to evaluate these methods. Freehand 3D ultrasound, the coupling of ultrasound with 3D motion capture, may provide such a benchmark.We measur... περισσότερα »
Are flexible flat feet associated with proximal joint problems in children?
Publication date: Available online 11 February 2016 *Source:*Gait & Posture Author(s): A. Kothari, P.C. Dixon, J. Stebbins, A.B. Zavatsky, T. Theologis The role of flexible flat feet (FF) in the development of musculoskeletal symptoms at joints proximal to the ankle is unclear. We undertook an observational study to investigate the relationship between foot posture and the proximal joints in children. It was hypothesised that reduced arch height would be associated with proximal joint symptoms and altered gait kinematics and kinetics particularly in the transverse plane at the hip an... περισσότερα »
Age-independent and age-dependent sex differences in gait pattern determined by principal component analysis
Publication date: Available online 11 February 2016 *Source:*Gait & Posture Author(s): Yoshiyuki Kobayashi, Hiroaki Hobara, Thijs A. Heldoorn, Makiko Kouchi, Masaaki Mochimaru Although various studies have reported significant sex differences in pelvic and/or hip-joint motion during normal walking in healthy adults, it is still unclear whether such differences are among the most dominant age-independent sex differences. This study was conducted to analyze the whole waveform of lower-extremity joint kinematics obtained from 191 healthy adults using a 1212□principal component analysis...περισσότερα »
The controversial p.Met34Thr variant in GJB2 gene: Two siblings, one genotype, two phenotypes.
[image: http:--linkinghub.elsevier.com-ihub-imag] Related Articles *The controversial p.Met34Thr variant in GJB2 gene: Two siblings, one genotype, two phenotypes.* Int J Pediatr Otorhinolaryngol. 2015 Aug;79(8):1316-9 Authors: Lameiras AR, Gonçalves AC, Santos R, O'Neill A, Reis LR, Matos TD, Fialho G, Caria H, Escada P Abstract INTRODUCTION: Recent advances in molecular genetics have increased the identification of genes and mutations responsible for inherited forms of hearing loss (HL), enabling early detection of these cases. Approximately, 60% of early-onset HL cases are due ...περισσότερα »
Usual interstitial pneumonia in asbestos exposed cohorts – concurrent idiopathic pulmonary fibrosis or atypical asbestosis?
Abstract Aims To determine if usual interstitial pneumonia pattern fibrosis is seen in asbestosis Methods and Results The occurrence of usual interstitial pneumonia pattern fibrosis was studied in 4 asbestos cohorts systematically referred following post mortem to the U.K. Pneumoconiosis Unit, Cardiff. The combined exposed workforce was over 25,000 persons. Over the 17 year period 233 subjects were identified, 210 had degrees of interstitial fibrosis with a fibrotic non-specific interstitial pneumonia pattern and sub-pleural accentuation and 3 cases showed usual interstitial pne... περισσότερα »
Hearts Kept Ticking with Titanium
[image: istock_000059187932_medium2.jpg] Medical implant providers should conduct material verification of all metals You will see many heart-shaped items this Valentine's Day. Boxes of chocolates, greeting cards, and balloons are just a few of the many heart-related gifts that can be seen in almost every store window. A heart-related item you may not see while walking down the Read the rest of this article The post Hearts Kept Ticking with Titanium appeared first on Accelerating Science. from Biomedical Engineering via ola Kala on Inoreader http://ift.tt/1Kdu4mc via IFTTT
Diamond Roses Mined for Valentine’s Day
[image: istock_000000229395_medium6.jpg] Valentine Roses and Diamonds by the Numbers According to a survey by the National Retail Federation, 37.8 percent of Americans will buy flowers for Valentine's Day 2015, spending a total of $2.1 billion. About Flowers estimates that 250 million roses will be produced for Valentine's Day. That same NRF survey said that nineteen percent will Read the rest of this article The post Diamond Roses Mined for Valentine's Day appeared first on Accelerating Science. from Biomedical Engineering via ola Kala on Inoreader http://ift.tt/1Kdu45U via I... περισσότερα »
Hearts Kept Ticking with Polyurethane
[image: heartpacemaker.jpg] Medical implant providers should conduct material verification of all polymers and plastics in pacemakers. Lives could depend on it. You will see many heart-shaped items this Valentine's Day. Heart-shaped plastic beads, decorations, cake toppers, and candy bowls can be seen in almost every store window. A heart-related item you may not see while walking down Read the rest of this article The post Hearts Kept Ticking with Polyurethane appeared first on Accelerating Science. from Biomedical Engineering via ola Kala on Inoreader http://ift.tt/1Q9hReD ... περισσότερα »
Alzheimer’s and Parkinson’s Disease Biobank: Centralizing Biomarker Discovery
[image: shutterstock_2478726791.jpg] Early diagnosis of Alzheimer's disease (AD) and Parkinson's disease (PD) aids clinicians in predicting disease progression in their patients. Presently, clinicians use Aβ42, tau proteins and α-synuclein; however, there is high variability in biomarker concentration measurements caused by differences in pre-analytical and analytical protocols for sample collection, sample handling and local assay handling. Biomarkers for Alzheimer's and Parkinson's disease Read the rest of this article The post Alzheimer's and Parkinson's Disease Biobank: Centra...περισσότερα »
How breast cancer chemotherapy increases the risk of leukaemia: Thoughts about a case of diffuse large B-cell lymphoma and leukaemia after breast cancer chemotherapy.
*How breast cancer chemotherapy increases the risk of leukaemia: Thoughts about a case of diffuse large B-cell lymphoma and leukaemia after breast cancer chemotherapy.* Cancer Biol Ther. 2016 Feb 9;:0 Authors: Zhang B, Zhang X, Li M, Kong L, Deng X, Yu J Abstract The latest studies suggest that prophylactic chemotherapy or adjuvant chemotherapy for early stage breast cancer may increase the leukaemia risk in patients. For patients with a low risk for breast cancer recurrence, physicians who make the choice for adjuvant therapy should consider the risk of its long-term side effect... περισσότερα »
Molecular Typing Characteristic and Drug Susceptibility Analysis of Mycobacterium tuberculosis Isolates from Zigong, China
Alexandros G. SfakianakisστοNews in OtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 11 δευτερόλεπτα
China is one of the 22 countries with high TB burden worldwide, and Sichuan contained the second-largest number of TB cases among all of the Chinese provinces. But the characteristics of Mycobacterium tuberculosis circulated in Zigong, Sichuan, were still unknown. To investigate the character and drug resistance profile, 265 clinical isolates were cultured from tuberculosis patient's sputum samples in the year of 2010, of which the genetic profile was determined by using Spoligotyping and MIRU-VNTR typing methods, and the drug sensibility testing to the four first-line and four se...περισσότερα »
Epidemic Profile of Maternal Syphilis in China in 2013
Alexandros G. SfakianakisστοNews in OtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 11 δευτερόλεπτα
Objective. The aim of this study was to investigate the epidemiological characteristics and adverse pregnancy outcomes of pregnant women with syphilis infection in China. Methods. Data were from China's Information System of Prevention of Mother-to-Child Transmission of Syphilis Management. Women who were registered in the system and delivered in 2013 were included in the analysis. Results. A total of 15884 pregnant women with syphilis infection delivered in China in 2013. 79.1% of infected women attended antenatal care at or before 37 gestational weeks; however, 55.4% received no...περισσότερα »
Substance P Receptor Signaling Mediates Doxorubicin-Induced Cardiomyocyte Apoptosis and Triple-Negative Breast Cancer Chemoresistance
Alexandros G. SfakianakisστοNews in OtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 11 δευτερόλεπτα
Doxorubicin (DOX), an anthracycline, is broadly considered the most active single agent available for treating breast cancer but has been known to induce cardiotoxicity. Although DOX is highly effective in treating triple-negative breast cancer (TNBC), DOX can have poor outcomes owing to induction of chemoresistance. There is an urgent need to develop new therapies for TNBC aimed at improving DOX outcome and DOX-induced cardiotoxicity. Substance P (SP), a neuropeptide involved in pain transmission is known to stimulate production of reactive oxygen species (ROS). Elevated cardiac ...περισσότερα »
Mucoepidermoid Carcinoma at the Mandibular Edentulous Ridge Mucosa: An Infrequent Location.
*Mucoepidermoid Carcinoma at the Mandibular Edentulous Ridge Mucosa: An Infrequent Location.* Otolaryngol Head Neck Surg. 2016 Feb 9; Authors: Alberto PL PMID: 26861234 [PubMed - as supplied by publisher] from #ENT-PubMed via ola Kala on Inoreader http://ift.tt/20qsqPX via IFTTT
Repair of Posterior Glottic Stenosis with the Modified Endoscopic Postcricoid Advancement Flap.
*Repair of Posterior Glottic Stenosis with the Modified Endoscopic Postcricoid Advancement Flap.* Otolaryngol Head Neck Surg. 2016 Feb 9; Authors: Damrose EJ, Beswick DM Abstract Posterior glottic stenosis is a difficult clinical problem that frequently results in bilateral vocal fold immobility, dyspnea, and tracheostomy dependence. Charts were reviewed of all patients undergoing a modified endoscopic postcricoid advancement flap procedure for posterior glottic stenosis between October 1, 2003, and June 30, 2015. Age, sex, operative findings, complications, and outcomes were not... περισσότερα »
Application of Lean Sigma to the Audiology Clinic at a Large Academic Center.
*Application of Lean Sigma to the Audiology Clinic at a Large Academic Center.* Otolaryngol Head Neck Surg. 2016 Feb 9; Authors: Huddle MG, Tirabassi A, Turner L, Lee E, Ries K, Lin SY Abstract OBJECTIVE: To apply Lean Sigma-a quality improvement strategy to eliminate waste and reduce variation and defects-to improve audiology scheduling and utilization in a large tertiary care referral center. The project goals included an increase in utilization rates of audiology block time and a reduction in appointment lead time. STUDY DESIGN: Prospective quality improvement study. SETTING: A... περισσότερα »
Definitive Surgical Therapy after Open Neck Biopsy for HPV-Related Oropharyngeal Cancer.
*Definitive Surgical Therapy after Open Neck Biopsy for HPV-Related Oropharyngeal Cancer.* Otolaryngol Head Neck Surg. 2016 Feb 9; Authors: Zenga J, Graboyes EM, Haughey BH, Paniello RC, Mehrad M, Lewis JS, Thorstad WL, Nussenbaum B, Rich JT Abstract OBJECTIVE: To determine the impact of prior open neck biopsy on the prognosis of patients with human papillomavirus (HPV)-related oropharyngeal squamous cell carcinoma (OPSCC) who are subsequently treated with a definitive surgical paradigm, including adjuvant therapy when indicated. STUDY DESIGN: Retrospective cohort. SETTING: Tertia... περισσότερα »
Head and Neck Paragangliomas: An Update on Evaluation and Management.
*Head and Neck Paragangliomas: An Update on Evaluation and Management.* Otolaryngol Head Neck Surg. 2016 Feb 9; Authors: Moore MG, Netterville JL, Mendenhall WM, Isaacson B, Nussenbaum B Abstract OBJECTIVE: Head and neck paragangliomas are a group of slow-growing hypervascular tumors associated with the paraganglion system. The approach to evaluate and treat these lesions has evolved over the last 2 decades. While radical surgery had been the traditional approach, improvements in diagnostic imaging as well as radiation therapy techniques have led to an emphasis on observation and ... περισσότερα »
Organized Hematoma: An Analysis of 84 Cases with Emphasis on Difficult Prediction and Favorable Management.
*Organized Hematoma: An Analysis of 84 Cases with Emphasis on Difficult Prediction and Favorable Management.* Otolaryngol Head Neck Surg. 2016 Feb 9; Authors: Pang W, Hu L, Wang H, Sha Y, Ma N, Wang S, Liu Q, Sun X, Wang D Abstract OBJECTIVE: To characterize features of organized hematoma (OH) that may cause considerable diagnostic difficulties. STUDY DESIGN: Case series with chart review. SETTING: Tertiary medical center. SUBJECTS AND METHODS: Eighty-four patients with pathologically confirmed OH over a 10-year period were retrospectively reviewed for clinical features, imaging fi... περισσότερα »
Effect of Radiofrequency Thermal Ablation Treatment on Nasal Ciliary Motility: A Study with Phase-Contrast Microscopy.
*Effect of Radiofrequency Thermal Ablation Treatment on Nasal Ciliary Motility: A Study with Phase-Contrast Microscopy.* Otolaryngol Head Neck Surg. 2016 Feb 9; Authors: Rosato C, Pagliuca G, Martellucci S, de Vincentiis M, Greco A, Fusconi M, De Virgilio A, Gallipoli C, Simonelli M, Gallo A Abstract OBJECTIVE: To investigate the efficacy of nasal ciliary motility after radiofrequency ablation treatment in patients with isolated inferior turbinate hypertrophy and to clarify how long until normal ciliary function is restored. STUDY DESIGN: Prospective, single-group, pretest-posttes... περισσότερα »
Readability and Understandability of Online Vocal Cord Paralysis Materials.
*Readability and Understandability of Online Vocal Cord Paralysis Materials.* Otolaryngol Head Neck Surg. 2016 Feb 9; Authors: Balakrishnan V, Chandy Z, Hseih A, Bui TL, Verma SP Abstract OBJECTIVE: Patients use several online resources to learn about vocal cord paralysis (VCP). The objective of this study was to assess the readability and understandability of online VCP patient education materials (PEMs), with readability assessments and the Patient Education Materials Evaluation Tool (PEMAT), respectively. The relationship between readability and understandability was then anal... περισσότερα »
Neurosarcoidosis Presenting as Aseptic Meningitis
Neurosarcoidosis Presenting as Aseptic Meningitis in an Immunosuppressed Renal Transplant Recipient.: Background: Sarcoidosis is a presumptive autoimmune disorder characterized by the presence of noncaseating granulomas and is usually treated successfully with immunosuppression. Methods and Results: Here, we describe the case of a 63-year-old male renal transplant recipient with a remote history of pulmonary sarcoidosis on chronic immunosuppression who developed recurrent aseptic meningitis and underwent brain biopsy revealing a diagnosis of neurosarcoidosis. Conclusions: This case hi... περισσότερα »
Cutaneous polyarteritis nodosa (CPAN)
Epidemiological, clinical and laboratory profile of cutaneous polyarteritis nodosa patients: Report of 22 cases and literature review via Autoimmunity Reviews Publication date: Available online 11 February 2016 *Source:*Autoimmunity Reviews Author(s): Paulo Ricardo Criado, Gabriela Franco Marques, Thamara Cristiane Alves Batista Morita, Jozélio Freire de Carvalho Cutaneous polyarteritis nodosa (CPAN) is a rare disease that affects small and middle caliber vessels of the deep dermis and subcutaneous tissue and its etiopathology remains yet to be understood. Methods: Retrospective review...περισσότερα »
Spontaneous Intracranial Hypotension Treated with a Targeted CT-Guided Epidural Blood Patch
Spontaneous intracranial hypotension (SIH) is an important cause of new daily persistent headache. It is thought to be due to spontaneous spinal cerebrospinal fluid (CSF) leaks, which probably have a multifactorial etiology. The classic manifestation of SIH is an orthostatic headache, but other neurological symptoms may be present. An epidural blood patch is thought to be the most effective treatment, but a blind infusion may be ineffective. We describe the case of a young man who developed an acute severe headache, with pain worsening when assuming an upright posture and relief g...περισσότερα »
Increased level of tumor necrosis factor-alpha (TNF-α) on the skin of Japanese obese males: measured by quantitative skin blotting
Increased level of tumor necrosis factor-alpha (TNF-α) on the skin of Japanese obese males: measured by quantitative skin blotting: Abstract Objective A state of chronic inflammation, characterized by an increased level of tumor necrosis factor-alpha (TNF-*α*), is often found in the obese population. The negative effects of elevated TNF-*α* are not limited to systemic metabolism. It also reportedly affects skin integrity. Recently, the relationship between obesity and skin fragility was reported; however, there has been little insight into how the level of TNF-*α* in the skin *in s... περισσότερα »
Second to Fourth Digit Ratios in Plastic Surgery
Second to Fourth Digit Ratios in Plastic Surgery: Author Information From the *Department of Plastic, Reconstructive and Aesthetic Surgery, University Hospital Galway, Galway, Ireland; and †National University of Ireland, Gaillimh, Galway, Ireland. Received for publication August 19, 2015; accepted December 2, 2015. Presented at the Irish Association of Plastic Surgeons Meeting, May 14-15 2015, Galway, Ireland. *Disclosure:* The authors have no financial interest to declare in relation to the content of this article. The Article Processing Charge was paid for by the The Irish Asso... περισσότερα »
Der LSD-Score ist für Stomatherapeuten und Ärzte verständlich, nachvollziehbar, ganzheitlich und praktikabel. Er kann sowohl zur Begriffserläuterung als auch zur Therapiestratifizierung verwendet werden.
LSD-Score: Zusammenfassung HintergrundObwohl peristomale Hautläsionen die häufigsten Stoma-assoziierten Komplikationen darstellen, gibt es keine allgemein anerkannte Nomenklatur und Klassifikation. MethodenEine aus 10 Mitgliedern intersektoral besetzte Expertengruppe entwickelte einen ganzheitlichen Bewertungsscore der peristomalen Hautläsion zur semiquantitativen Klassifizierung und Therapiestratifizierung. Dieser Score basiert auf von Stomatherapeuten und behandelnden Ärzten beurteilbaren Kriterien. ErgebnisseDer Score benennt und bewertet 3 graduierbare Kategorien: L = ... περισσότερα »
The philosopher's stone
Fat grafting & the philosopher's stone: 2014 and 2015 saw a surge of review articles evaluating various fat processing techniques, all of which concluded that no specific technique significantly effects fat graft survival.1–7 Surgeons continue to look for the perfect recipe that would allow for 100% graft survival. This pursuit of the “philosopher's stone” of fat grafting dates back to a 2012 review article urging researchers to continue the magnum opus.8 Similar to the alchemists' search, this great work has no end in sight.
Intraoperative Instrument Fracture During Endoscopic Dacryocystorhinostomy.
Intraoperative Instrument Fracture During Endoscopic Dacryocystorhinostomy.:
Fungus Ball of the Maxillary Sinus Presenting with Epiphora.
Fungus Ball of the Maxillary Sinus Presenting with Epiphora.: The authors report a case of fungus ball of the maxillary sinus with bone erosion presenting with epiphora, which was diagnosed after treatment failure using silicone intubation for nasolacrimal duct obstruction. Symptoms of sinus fungus ball are similar to those of chronic bacterial rhinosinusitis, although occasionally asymptomatic. To our knowledge, epiphora has never been reported as a symptom of sinus fungus ball. The purpose of this report is to emphasize the importance of considering sinonasal causes when evaluatin...περισσότερα »
Subdermal Lipotransfer of Mature Adipocytes or Adipose-Derived Stem Cells Alone
Positive Effects of Subdermal Lipotransfer on Pig's Upper Eyelid Skin: Mature Adipocytes or Adipose-Derived Stem Cells Alone Contribute Little and Only Cotransplantation of Them Can Generate the benefits.: Background: Many studies have shown that autologous fat grafting and cell-assisted lipotransfer can improve skin quality, with both mature adipocytes (MAs) and adipose-derived stem cells (ADSCs) considered to play a role. However, it is unclear whether transplantation of ADSCs or MAs has the same impact on the overlying skin. Methods: Nine pigs were divided into 3 equal groups, wit... περισσότερα »
Subdermal Lipotransfer on Upper Eyelid Skin
Positive Effects of Subdermal Lipotransfer on Pig's Upper Eyelid Skin: Mature Adipocytes or Adipose-Derived Stem Cells Alone Contribute Little and Only Cotransplantation of Them Can Generate the benefits.: Background: Many studies have shown that autologous fat grafting and cell-assisted lipotransfer can improve skin quality, with both mature adipocytes (MAs) and adipose-derived stem cells (ADSCs) considered to play a role. However, it is unclear whether transplantation of ADSCs or MAs has the same impact on the overlying skin. Methods: Nine pigs were divided into 3 equal groups, wit... περισσότερα »
Subdermal Lipotransfer of Mature Adipocytes or Adipose-Derived Stem Cells Alone
Alexandros G. SfakianakisστοCell and Tissue Research by Alexandros G. SfakianakisΠριν από 19 δευτερόλεπτα
Positive Effects of Subdermal Lipotransfer on Pig's Upper Eyelid Skin: Mature Adipocytes or Adipose-Derived Stem Cells Alone Contribute Little and Only Cotransplantation of Them Can Generate the benefits.: Background: Many studies have shown that autologous fat grafting and cell-assisted lipotransfer can improve skin quality, with both mature adipocytes (MAs) and adipose-derived stem cells (ADSCs) considered to play a role. However, it is unclear whether transplantation of ADSCs or MAs has the same impact on the overlying skin. Methods: Nine pigs were divided into 3 equal groups, wit... περισσότερα »
Usual interstitial pneumonia in asbestos exposed cohorts – concurrent idiopathic pulmonary fibrosis or atypical asbestosis?
Alexandros G. SfakianakisστοCell and Tissue Research by Alexandros G. SfakianakisΠριν από 19 δευτερόλεπτα
Abstract Aims To determine if usual interstitial pneumonia pattern fibrosis is seen in asbestosis Methods and Results The occurrence of usual interstitial pneumonia pattern fibrosis was studied in 4 asbestos cohorts systematically referred following post mortem to the U.K. Pneumoconiosis Unit, Cardiff. The combined exposed workforce was over 25,000 persons. Over the 17 year period 233 subjects were identified, 210 had degrees of interstitial fibrosis with a fibrotic non-specific interstitial pneumonia pattern and sub-pleural accentuation and 3 cases showed usual interstitial pne... περισσότερα »
Diagnostic Approaches to Metastatic Hepatocellular Carcinoma of the Orbit.
Diagnostic Approaches to Metastatic Hepatocellular Carcinoma of the Orbit.: Orbital metastasis of hepatocellular carcinoma is exceedingly rare and caries a grave prognosis. Three cases of metastatic orbital hepatocellular carcinoma in which the primary tumor was initially unknown and the diagnostic challenges encountered are presented. With hepatocellular carcinoma, open biopsy and palliative tumor debulking has an increased bleeding risk due to the highly vascular nature of the tumor and coagulopathy associated with chronic liver disease. As an alternative, fine needle aspiration bi... περισσότερα »
Changes in Tear Film Characteristics in Patients with Idiopathic Dacryoadenitis.
Changes in Tear Film Characteristics in Patients with Idiopathic Dacryoadenitis.: Purpose: To evaluate the tear-film meniscus with optical coherence tomography (OCT) in patients with idiopathic dacryoadenitis and to determine its relationships with the clinical tests. Methods: Sixteen patients with unilateral idiopathic dacryoadenitis were included in the study. Patients with idiopathic dacryoadenitis with affected sites (group 1), with contralateral sites (group 2) and healthy participants (group 3) completed the ocular surface disease index before optical coherence tomography deter...περισσότερα »
Nontubulation Repair of Peripheral Nerve Gap Using Heparin/Alginate Gel Combined with b-FGF
Nontubulation Repair of Peripheral Nerve Gap Using Heparin/Alginate Gel Combined with b-FGF: [image: image]Summary: All artificial nerve grafts have a tubular structure, and they guide axonal regrowth through the tube from the proximal side toward the peripheral side. Based on the results of our experimental study using animals, we used alginate gel without a tubular structure as an artificial nerve graft for digital nerve repair and evaluated peripheral nerve regeneration. In 2 patients, a gap due to digital nerve injury was bridged with controlled-release heparin/alginate gel comb... περισσότερα »
Local heating of the wound with dressings soaked in saline at 42°C can reduce postoperative bleeding
: a single-blind, split-mouth, randomised controlled clinical trial via British Journal of Oral and Maxillofacial Surgery Publication date: Available online 10 February 2016 *Source:*British Journal of Oral and Maxillofacial Surgery Author(s): Afshin Haraji, Vahid Rakhshan, Vasim Hosseini Control of bleeding is essential during oral procedures. Although various chemical agents have been introduced and tested, hot water dressing has not to our knowledge been assessed before. Studies of operations for epistaxis or sinus conditions have suggested that irrigation with hot water can reduce b...περισσότερα »
Botulinum Toxin as a Therapeutic Agent to Prevent Relapse in Deep Bite Patients
Botulinum Toxin as a Therapeutic Agent to Prevent Relapse in Deep Bite Patients IntroductionThe aetiology of deep bite is multifactorial. One of the causes is increased muscular activity. This makes the treatment of deep bite malocclusions difficult and often results in relapse in many cases. In this work we compared patients with surgical orthognathic treatment only and surgical orthognathic treatment with additional injections of botulinum toxin after mandibular advancement for class II division 2 malocclusion.Material and MethodsThis is a prospective study. Adult patients were a... περισσότερα »
The adenomatoid odontogenic tumour
The adenomatoid odontogenic tumour: an update of selected issues: The aim of this update was to present the recent notable progress within remaining questions relating to the adenomatoid odontogenic tumour (AOT). Selected issues that were studied included the following: (i) AOT history and terminology, (ii) the so-called peripheral AOT, (iii) AOT and the gubernaculum dentis and (iv) the so-called adenomatoid odontogenic cyst (AOC). The earliest irrefutable European case of AOT was described in 1915 by Harbitz as ‘cystic adamantoma’. Recently, Ide et al. have traced two Japanese cas...περισσότερα »
Obstructive sleep apnea and cognition in parkinson's disease
Obstructive sleep apnea and cognition in parkinson's disease: • Patients with Parkinson's disease and obstructive sleep apnea score significantly lower than those with Parkinson's disease without obstructive sleep apnea on tests of cognitive function.• Obstructive sleep apnea is a significant predictor of poor cognition.• Treating obstructive sleep apnea in Parkinson's disease does not result in improvements in cognition. ObjectiveObstructive sleep apnea (OSA) is very common in Parkinson's disease (PD). OSA is known to impact patients' cognition. The present study assessed whethe...περισσότερα »
Dynamic Range Across Music Genres and the Perception of Dynamic Compression in Hearing-Impaired Listeners
Dynamic Range Across Music Genres and the Perception of Dynamic Compression in Hearing-Impaired Listeners: Dynamic range compression serves different purposes in the music and hearing-aid industries. In the music industry, it is used to make music louder and more attractive to normal-hearing listeners. In the hearing-aid industry, it is used to map the variable dynamic range of acoustic signals to the reduced dynamic range of hearing-impaired listeners. Hence, hearing-aided listeners will typically receive a dual dose of compression when listening to recorded music. The present stu... περισσότερα »
A Binaural Cochlear Implant Sound Coding Strategy Inspired by the Contralateral Medial Olivocochlear Reflex.
A Binaural Cochlear Implant Sound Coding Strategy Inspired by the Contralateral Medial Olivocochlear Reflex.: Objectives: In natural hearing, cochlear mechanical compression is dynamically adjusted via the efferent medial olivocochlear reflex (MOCR). These adjustments probably help understanding speech in noisy environments and are not available to the users of current cochlear implants (CIs). The aims of the present study are to: (1) present a binaural CI sound processing strategy inspired by the control of cochlear compression provided by the contralateral MOCR in natural hearing;... περισσότερα »
Testing Speech Recognition in Spanish-English Bilingual Children with the Computer-Assisted Speech Perception Assessment (CASPA): Initial Report.
Testing Speech Recognition in Spanish-English Bilingual Children with the Computer-Assisted Speech Perception Assessment (CASPA): Initial Report.: This study evaluated the English version of Computer-Assisted Speech Perception Assessment (E-CASPA) with Spanish-English bilingual children. E-CASPA has been evaluated with monolingual English speakers ages 5 years and older, but it is unknown whether a separate norm is necessary for bilingual children. Eleven Spanish-English bilingual and 12 English monolingual children (6 to 12 years old) with normal hearing participated. Responses wer... περισσότερα »
Angioleiomyoma of the External Auditory Canal
Angioleiomyoma of the External Auditory Canal: [image: image]
Long-term Stability of the Active Middle-ear Implant with Floating-mass Transducer Technology: A Single-center Study
Long-term Stability of the Active Middle-ear Implant with Floating-mass Transducer Technology: A Single-center Study: [image: image] Objective: To examine the long-term results of an active middle-ear implant (AMEI) with floating-mass transducer (FMT) technology. Study Design: Prospective cohort study of German-speaking patients implanted with an AMEI between 2006 and 2013. Setting: Single-center study. Patients: Eighty-three patients. Intervention: AMEI with FMT technology implantation. Main Outcome Measures: Long-term outcome (27 mo; range, 12–84 mo) for FMT position in correlation ... περισσότερα »
Minimal Growth of Intracochlear Schwannoma Over 7 Years
Minimal Growth of Intracochlear Schwannoma Over 7 Years: [image: image]
Temporoparietal Fascial Flap to Eliminate Wound Breakdown in Subtotal Petrosectomy for Chronic Discharging Ears
The Use of Temporoparietal Fascial Flap to Eliminate Wound Breakdown in Subtotal Petrosectomy for Chronic Discharging Ears: [image: image]Objective: To find out if the use of the vascularized temporo-parietal fascial flap (TPFF) reduces postoperative infection or wound breakdown in subtotal petrosectomy for chronic discharging ears. Patients: A retrospective review on 26 subtotal petrosectomies with blind pit closures on chronic discharging ears performed by a single surgeon between 2000 and 2015 was performed. All patients had a minimum follow-up period of 6 months. Intervention: El...περισσότερα »
Dickkopf-related Protein 3 as a Sensitive and Specific Marker for Cerebrospinal Fluid Leaks
Dickkopf-related Protein 3 as a Sensitive and Specific Marker for Cerebrospinal Fluid Leaks: [image: image] Hypothesis: Cerebrospinal fluid (CSF) can be identified by using an enzyme-linked immunosorbent assay (ELISA) for Dickkopf-related protein 3 (DKK3). Background: Cerebrospinal fluid leakage from the subarachnoid space is a potentially alarming condition that, left unrepaired, may result in increased risk of meningitis and encephalitis. Current biochemical methods of CSF leak detection involve using beta-2-transferrin-based or beta trace protein-based assays, both of which, at ... περισσότερα »
Prevalence of Pulsatile Tinnitus Among Patients With Migraine
Prevalence of Pulsatile Tinnitus Among Patients With Migraine: [image: image] Objective: To examine the prevalence of pulsatile tinnitus (PT) among patients with a diagnosis of migraine and to determine if treatment of migraine improves symptoms. Study Design: Single-institution retrospective patient review. Setting: Academic tertiary referral center. Patients: Billing data capturing ICD-9 codes 346.xx and 388.3x was used to identify patients with history of migraine and tinnitus. Patients were excluded if the symptom of PT could be attributed to an alternate diagnosis. Data were ext... περισσότερα »
Isolated Vestibular Suppression Impairment With Vestibular Migraine: A Phenotypic CANVAS Variant
Isolated Vestibular Suppression Impairment With Vestibular Migraine: A Phenotypic CANVAS Variant: [image: image] Hypothesis: Cerebellar Ataxia with Neuropathy and Vestibular Areflexia (CANVAS) is likely to have a genetic basis. We describe the unique eye movement features of a possible phenotypic CANVAS variant. Background: The patient comes from a large CANVAS kindred (four out of nine siblings) and has sensory neuropathy, cerebellar eye signs, and vestibular migraine (VM), but otherwise normal vestibular function. Methods: We recorded eye and head movements using the gold standard ... περισσότερα »
Cochlear Implantation in a Patient With Pfeiffer Syndrome and Temporal Bone Vascular Anomalies
Cochlear Implantation in a Patient With Pfeiffer Syndrome and Temporal Bone Vascular Anomalies: [image: image]Objective: Pfeiffer syndrome is a rare craniosynostotic disorder resulting in premature bony fusion of the skull, which can result in abnormal temporal bone and vascular anatomy and hearing loss. Cochlear implantation in these patients requires thoughtful surgical planning given the potential for limited access to the cochlea because of subcutaneous or intratemporal vasculature. Herein, we present a patient with Pfeiffer syndrome who underwent successful cochlear implantation... περισσότερα »
Osseointegration Failure Between Osseointegrated Bone Conduction Device Models in Pediatric Patients
A Comparative Review of Osseointegration Failure Between Osseointegrated Bone Conduction Device Models in Pediatric Patients: Objective: Compare rates of osseointegration failure (OIF) between system 2 (200 series) and system 3 (BI300) osseointegrated bone conduction device (OCBD) models. Study Design: Case series with chart review. Setting: Tertiary referral center. Patients: Pediatric patients who were implanted with either system 2 or system 3 OCBD between May 2009 and July 2014 at Arkansas Children's Hospital. Interventions: Implantation with either system 2 or system 3 OCBD usin...περισσότερα »
Hearing Preservation Outcomes With a Mid-Scala Electrode in Cochlear Implantation
Hearing Preservation Outcomes With a Mid-Scala Electrode in Cochlear Implantation: [image: image]Objective: To evaluate hearing preservation (HP) outcomes in adult cochlear implant recipients with a mid-scala electrode. Setting: Tertiary academic center. Patients: Adult patients implanted with a mid-scala electrode between May 2013 and July 2015. Interventions: Cochlear implantation. Main Outcome Measure(s): Age, sex, surgical approach, residual hearing changes post cochlear implantation, HP rates using different published classifications, and speech perception scores. Results: Fifty ... περισσότερα »
Impaired Perception of Sensory Consonance and Dissonance in Cochlear Implant Users
Impaired Perception of Sensory Consonance and Dissonance in Cochlear Implant Users: [image: image]Hypothesis: In light of previous research demonstrating poor pitch perception in cochlear implant (CI) users, we hypothesized that the presence of consonant versus dissonant chord accompaniment in real-world musical stimuli would not impact subjective assessment of degree of pleasantness in CI users. Background: Consonance/dissonance are perceptual features of harmony resulting from pitch relationships between simultaneously presented musical notes. Generally, consonant sounds are percei...περισσότερα »
Teratoma of the Middle Ear With Cholesteatoma
Teratoma of the Middle Ear With Cholesteatoma: [image: image]
Computed Tomography Estimation of Cochlear Duct Length Can Predict Full Insertion in Cochlear Implantation
Computed Tomography Estimation of Cochlear Duct Length Can Predict Full Insertion in Cochlear Implantation: [image: image] Objective: To compare the rates of full insertion of electrodes and hearing outcomes obtained with 28-mm and 31-mm cochlear implant electrode arrays. To assess whether cochlear duct length (CDL) estimated by preoperative computed tomography (CT) predicts whether an electrode is fully inserted. Study Design: A cohort study compared electrodes inserted and hearing outcomes after implantation with 28-mm or 31-mm arrays. CDL estimated from preoperative CT was compar...περισσότερα »
Vestibular Migraine: Vestibular Symptom May Identify Different Subgroups
Vestibular Migraine: Vestibular Symptom May Identify Different Subgroups: Abstract Objective: The objective of this study was to evaluate patients with vestibular migraine and analyze whether different vestibular symptoms were able to discriminate different subgroups. Patients: Eighty-three patients (73 women, mean age 42 yr) who fulfilled the criteria for vestibular migraine were selected. Intervention: Participants were divided into two groups according to their vestibular symptoms: spontaneous vertigo (SV) or triggered vertigo (TV). In each group, migraine subtype (migraine with a...περισσότερα »
Intracochlear Drug Delivery Through the Oval Window in Fresh Cadaveric Human Temporal Bones
Intracochlear Drug Delivery Through the Oval Window in Fresh Cadaveric Human Temporal Bones: [image: image]Hypothesis: Drug delivered to the oval window can diffuse to the apex of the human cochlea. Background: We have previously demonstrated that zoledronate, a nitrogen-containing bisphosphonate, can arrest the sensorineural hearing loss in cochlear otosclerosis. We have also shown that, in animals, delivery of bisphosphonate into the cochlea can dramatically increase delivery efficiency. Intracochlear drug delivery has the potential to increase local concentration of drug while dec...περισσότερα »
Cerebellopontine Angle Mixed Tumor in Type 2 Neurofibromatosis
Cerebellopontine Angle Mixed Tumor in Type 2 Neurofibromatosis: [image: image]
Book review.
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 32 δευτερόλεπτα
Book review. Int J Audiol. 2016 Mar;55(3):196 Authors: Gilbert J PMID: 26862923 [PubMed – as supplied by publisher] from #ORL-AlexandrosSfakianakis via ola Kala on Inoreader http://ift.tt/1QXI8Q6 via IFTTT
Book Review.
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 32 δευτερόλεπτα
Book Review. Int J Audiol. 2016 Mar;55(3):195 Authors: Marc B PMID: 26862922 [PubMed – as supplied by publisher] from #ORL-AlexandrosSfakianakis via ola Kala on Inoreader http://ift.tt/23YDFnq via IFTTT
How breast cancer chemotherapy increases the risk of leukaemia: Thoughts about a case of diffuse large B-cell lymphoma and leukaemia after breast cancer chemotherapy.
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 32 δευτερόλεπτα
How breast cancer chemotherapy increases the risk of leukaemia: Thoughts about a case of diffuse large B-cell lymphoma and leukaemia after breast cancer chemotherapy. Cancer Biol Ther. 2016 Feb 9;:0 Authors: Zhang B, Zhang X, Li M, Kong L, Deng X, Yu J Abstract The latest studies suggest that prophylactic chemotherapy or adjuvant chemotherapy for […]
Book review.
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 32 δευτερόλεπτα
Book review. Int J Audiol. 2016 Mar;55(3):196 Authors: Gilbert J PMID: 26862923 [PubMed – as supplied by publisher] from #ORL-AlexandrosSfakianakis via ola Kala on Inoreader http://ift.tt/1QXI8Q6 via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
Book Review.
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 32 δευτερόλεπτα
Book Review. Int J Audiol. 2016 Mar;55(3):195 Authors: Marc B PMID: 26862922 [PubMed – as supplied by publisher] from #ORL-AlexandrosSfakianakis via ola Kala on Inoreader http://ift.tt/23YDFnq via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
How breast cancer chemotherapy increases the risk of leukaemia: Thoughts about a case of diffuse large B-cell lymphoma and leukaemia after breast cancer chemotherapy.
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 32 δευτερόλεπτα
How breast cancer chemotherapy increases the risk of leukaemia: Thoughts about a case of diffuse large B-cell lymphoma and leukaemia after breast cancer chemotherapy. Cancer Biol Ther. 2016 Feb 9;:0 Authors: Zhang B, Zhang X, Li M, Kong L, Deng X, Yu J Abstract The latest studies suggest that prophylactic chemotherapy or adjuvant chemotherapy for […]
Differences in coda voicing trigger changes in gestural timing: A test case from the American English diphthong /aɪ/
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 32 δευτερόλεπτα
Publication date: May 2016 Source:Journal of Phonetics, Volume 56 Author(s): Anne Pycha, Delphine Dahan We investigate the hypothesis that duration and spectral differences in vowels before voiceless versus voiced codas originate from a single source, namely the reorganization of articulatory gestures relative to one another in time. As a test case, we examine the American […]
The acoustic correlates of lexical stress in Israeli Hebrew
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 32 δευτερόλεπτα
Publication date: May 2016 Source:Journal of Phonetics, Volume 56 Author(s): Vered Silber-Varod, Hagit Sagi, Noam Amir Lexical stress is an omnipresent phenomenon in spoken language, serving in many cases to disambiguate lexically identical words. Lexical stress in Spoken Israeli Hebrew is usually either penultimate or final, however its prosodic cues have not been measured systematically. […]
Nontubulation Repair of Peripheral Nerve Gap Using Heparin/Alginate Gel Combined with b-FGF
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 32 δευτερόλεπτα
Summary: All artificial nerve grafts have a tubular structure, and they guide axonal regrowth through the tube from the proximal side toward the peripheral side. Based on the results of our experimental study using animals, we used alginate gel without a tubular structure as an artificial nerve graft for digital nerve repair and evaluated peripheral […]
Interference of functional monomers with polymerization efficiency of adhesives
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 32 δευτερόλεπτα
The degree of conversion (DC) of camphorquinone/amine-based adhesives is affected by acidic functional monomers as a result of inactivation of the amine co-initiator through an acid–base reaction. During bonding, functional monomers of self-etch adhesives chemically interact with hydroxyapatite (HAp). Here, we tested in how far the latter interaction of functional monomers with HAp counteracts the […]
Sensorineural Hearing Loss in Cholesteatoma
Sensorineural Hearing Loss in Cholesteatoma: Objective: To determine whether middle ear cholesteatoma is associated with, sensorineural hearing loss, and whether patient age, cholesteatoma growth pattern, or, air bone gap size contribute to inner ear impairment. Study Design: Cross-sectional comparative. Setting: A tertiary hospital. Patients: The subjects were 115 patients with middle ear cholesteatoma in one ear, and normal video-otoscopy in the contralateral ear (CLE). Interventions: Otoendoscopy, pure-tone audiometry. Main Outcome Measures: Bone conduction (BC) threshold differences... περισσότερα »
A New Transcutaneous Bone Conduction Hearing Device
Objective and Subjective Outcome of a New Transcutaneous Bone Conduction Hearing Device: Half-year Follow-up of the First 12 Nordic Implantations: Objective: To examine the objective and subjective outcome of a new transcutaneous bone conduction hearing device. Study Design: Prospective, consecutive case series. Patients: Twelve patients were implanted. Eight patients had a conductive/mixed (con/mix) hearing loss. Four had single sided deafness. Main Outcome Measures: At half-year follow-up, aided and unaided sound field hearing was evaluated by 1) warble tone thresholds, 2) pure-tone ...περισσότερα »
Meniett Therapy for Ménière's Disease
Meniett Therapy for Ménière's Disease: An Updated Meta-analysis: [image: image] Objective: To re-evaluate the efficacy of Meniett therapy for the treatment of Ménière's disease (MD). Data Sources: PubMed, Embase, Cochrane Library, Clinicaltrials.gov, ChiCTR, and the CNKI database were searched for articles in English and Chinese published before August 31, 2015. Study Selection: Included in this meta-analysis were studies that dealt with outcomes of Meniett therapy for the treatment of MD, including randomized controlled clinical trials, case-control studies, and prospective or retr...περισσότερα »
Inherited forms of hearing loss (HL)
[image: http:--linkinghub.elsevier.com-ihub-imag] *The controversial p.Met34Thr variant in GJB2 gene: Two siblings, one genotype, two phenotypes.* Int J Pediatr Otorhinolaryngol. Authors: Lameiras AR, Gonçalves AC, Santos R, O'Neill A, Reis LR, Matos TD, Fialho G, Caria H, Escada P Abstract INTRODUCTION: Recent advances in molecular genetics have increased the identification of genes and mutations responsible for inherited forms of hearing loss (HL), enabling early detection of these cases. Approximately, 60% of early-onset HL cases are due to genetic causes, of which 70% are no... περισσότερα »
Whole-brain grey matter density predicts balance stability
Whole-brain grey matter density predicts balance stability irrespective of age and protects older adults from falling via Gait & Posture Publication date: March 2016 *Source:*Gait & Posture, Volume 45 Author(s): Matthieu P. Boisgontier, Boris Cheval, Peter van Ruitenbeek, Oron Levin, Olivier Renaud, Julien Chanal, Stephan P. Swinnen Functional and structural imaging studies have demonstrated the involvement of the brain in balance control. Nevertheless, how decisive grey matter density and white matter microstructural organisation are in predicting balance stability, and especially whe... περισσότερα »
Development of an analytical method to quantify PBDEs, OH-BDEs, HBCDs, 2,4,6-TBP, EH-TBB, and BEH-TEBP in human serum
Abstract Polybrominated diphenyl ethers (PBDEs) flame retardants (FRs) were phased-out in the mid-2000s (penta- and octaBDE) and 2013 (decaBDE); however, their hydroxylated metabolites (OH-BDEs) are still commonly detected in human serum. Today, novel FRs such as Firemaster® 550, a mixture that contains two brominated compounds, EH-TBB and BEH-TEBP are used as replacements for PBDEs in some applications, and there is a need to develop a comprehensive analytical method to assess exposure to both legacy PBDEs and novel FRs. This study developed a solid-phase extraction (SPE)-based m... περισσότερα »
Development of an analytical method to quantify PBDEs, OH-BDEs, HBCDs, 2,4,6-TBP, EH-TBB, and BEH-TEBP in human serum
Abstract Polybrominated diphenyl ethers (PBDEs) flame retardants (FRs) were phased-out in the mid-2000s (penta- and octaBDE) and 2013 (decaBDE); however, their hydroxylated metabolites (OH-BDEs) are still commonly detected in human serum. Today, novel FRs such as Firemaster® 550, a mixture that contains two brominated compounds, EH-TBB and BEH-TEBP are used as replacements for PBDEs in some applications, and there is a need to develop a comprehensive analytical method to assess exposure to both legacy PBDEs and novel FRs. This study developed a solid-phase extraction (SPE)-based m... περισσότερα »
The effect of fluctuating maskers on speech understanding of high-performing cochlear implant users
The effect of fluctuating maskers on speech understanding of high-performing cochlear implant users: 10.3109/14992027.2015.1128124<br>Stefan Zirn Abstract *Objective*: The present study evaluated whether the poorer baseline performance of cochlear implant (CI) users or the technical and/or physiological properties of CI stimulation are responsible for the absence of masking release. *Design*: This study measured speech reception thresholds (SRTs) in continuous and modulated noise as a function of signal to noise ratio (SNR). *Study sample*: A total of 24 subjects participated: ... περισσότερα »
Effect of continuous positive airway pressure on arterial stiffness in patients with obstructive sleep apnea and hypertension: a meta-analysis
Effect of continuous positive airway pressure on arterial stiffness in patients with obstructive sleep apnea and hypertension: a meta-analysis: AbstractArterial stiffness has been recognized as a predictor of cardiovascular and all-cause mortality in hypertensive patients. However, the impact of continuous positive airway pressure (CPAP) on arterial stiffness in patients with OSA and hypertension remains inconclusive. We performed a meta-analysis to determine whether effective CPAP therapy could decrease arterial stiffness. Two reviewers independently searched PubMed, Embase, Web o... περισσότερα »
The long-term fate of epistaxis patients with exposure to antithrombotic medication
The long-term fate of epistaxis patients with exposure to antithrombotic medication: AbstractThe goal of this study was to evaluate independent risk factors for long-term epistaxis recurrences and their severity. Individual retrospective cohort study-2b level of evidence. The medical information of 603 emergency epistaxis patients was acquired during a former study. This cohort has been contacted 6 years later by conventional mail and asked to answer a specific paper questionnaire. The following parameters were evaluated: recurrent epistaxis episodes, need for a surgical intervent... περισσότερα »
Classification of parotidectomies
Classification of parotidectomies: a proposal of the European Salivary Gland Society: AbstractThe objective of this study is to provide a comprehensive classification system for parotidectomy operations. Data sources include Medline publications, author’s experience, and consensus round table at the Third European Salivary Gland Society (ESGS) Meeting. The Medline database was searched with the term “parotidectomy” and “definition”. The various definitions of parotidectomy procedures and parotid gland subdivisions extracted. Previous classification systems re-examined and a new cl...περισσότερα »
Microscopic versus endoscopic transsphenoidal surgery for pituitary adenoma: analysis of surgical safety in 221 consecutive patients
Microscopic versus endoscopic transsphenoidal surgery for pituitary adenoma: analysis of surgical safety in 221 consecutive patients: Transsphenoidal route is now considered the gold standard for the removal of pituitary adenoma. Up to date, no clear superiority in terms of efficacy has been demonstrated between transsphenoidal microscopic and endoscopic approaches. Surgical safety may be a relevant argument in favor or against the choice of one of the two surgical approaches. In our experience, the microscope and the endoscope are both safe instruments for the resection of pituitary...περισσότερα »
How breast cancer chemotherapy increases the risk of leukaemia: Thoughts about a case of diffuse large B-cell lymphoma and leukaemia after breast cancer chemotherapy.
*How breast cancer chemotherapy increases the risk of leukaemia: Thoughts about a case of diffuse large B-cell lymphoma and leukaemia after breast cancer chemotherapy.* Cancer Biol Ther. 2016 Feb 9;:0 Authors: Zhang B, Zhang X, Li M, Kong L, Deng X, Yu J Abstract The latest studies suggest that prophylactic chemotherapy or adjuvant chemotherapy for early stage breast cancer may increase the leukaemia risk in patients. For patients with a low risk for breast cancer recurrence, physicians who make the choice for adjuvant therapy should consider the risk of its long-term side effect... περισσότερα »
Development of an analytical method to quantify PBDEs, OH-BDEs, HBCDs, 2,4,6-TBP, EH-TBB, and BEH-TEBP in human serum
Alexandros G. SfakianakisστοNews in OtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 39 δευτερόλεπτα
Abstract Polybrominated diphenyl ethers (PBDEs) flame retardants (FRs) were phased-out in the mid-2000s (penta- and octaBDE) and 2013 (decaBDE); however, their hydroxylated metabolites (OH-BDEs) are still commonly detected in human serum. Today, novel FRs such as Firemaster® 550, a mixture that contains two brominated compounds, EH-TBB and BEH-TEBP are used as replacements for PBDEs in some applications, and there is a need to develop a comprehensive analytical method to assess exposure to both legacy PBDEs and novel FRs. This study developed a solid-phase extraction (SPE)-based m... περισσότερα »
Can a Tubal Pregnancy Be Cured or Prevented?
Alexandros G. SfakianakisστοNews in OtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 39 δευτερόλεπτα
Are you a victim of Tubal Pregnancy? Do you have awareness about this type of pregnancy condition or have you undergone certain tests to confirm that you pregnancy is normal? The day you decide that you want to have child is one of the most important days of your married lives due to the fact that welcoming a baby into this world is not an easy task it requires you to undergo immense pain & stress especially if you are new to this condition. Initially you will worry as to whether you can conceive a baby or not, questions like you might be suffering from infertility problems or you ... περισσότερα »
Trial to Determine Optimal Phase II Dose of the Oral Dual CAIX Inhibitor/ Radiosensitizer
Alexandros G. SfakianakisστοHead,Neck,Brain,Cervical Spine and Esophageal Cancers by Alexandros G. SfakianakisΠριν από 39 δευτερόλεπτα
Trial to Determine Optimal Phase II Dose of the Oral Dual CAIX Inhibitor/ Radiosensitizer: *Conditions*: Solid Tumors; Head and Neck Neoplasms *Intervention*: Drug: 2-(2-methyl-5-nitro-1H-imidazol-1-yl)ethylsulfamide or DTP348 *Sponsor*: Maastricht Radiation Oncology This is a Phase I multicenter, open-label, dose-escalation study of DTP348. DTP 348 is an oral dual drug with two mechanisms of action: 1. carbonic anhydrase IX inhibitor which acidifies the intracellular pH through the sulfamide components 2. radio sensitizer of hypoxic cells through its 5-nitroimida... περισσότερα »
Head and Neck Squamous Cell Carcinoma (HNSCC)PET-CT Pilot Study
Alexandros G. SfakianakisστοHead,Neck,Brain,Cervical Spine and Esophageal Cancers by Alexandros G. SfakianakisΠριν από 39 δευτερόλεπτα
Head and Neck Squamous Cell Carcinoma (HNSCC)PET-CT Pilot Study: *Condition*: Head and Neck Squamous Cell Carcinoma *Intervention*: Drug: 18-F FDG *Sponsor*: University Health Network, Toronto The purpose of this study is to see how useful the information provided from Positron Emission Tomography (PET) scans can be in the actual planning and delivery of radiation treatment to patients who have head and neck cancers. Patients participating in this study, will have (in addition to their routine tests) a PET scan before and during their radiation treatment. Following the inte... περισσότερα »
Can a Tubal Pregnancy Be Cured or Prevented?
Are you a victim of Tubal Pregnancy? Do you have awareness about this type of pregnancy condition or have you undergone certain tests to confirm that you pregnancy is normal? The day you decide that you want to have child is one of the most important days of your married lives due to the fact that welcoming a baby into this world is not an easy task it requires you to undergo immense pain & stress especially if you are new to this condition. Initially you will worry as to whether you can conceive a baby or not, questions like you might be suffering from infertility problems or you ... περισσότερα »
Book review.
*Book review.* Int J Audiol. 2016 Mar;55(3):196 Authors: Gilbert J PMID: 26862923 [PubMed - as supplied by publisher] from #ENT-PubMed via ola Kala on Inoreader http://ift.tt/1QXI8Q6 via IFTTT
Book Review.
*Book Review.* Int J Audiol. 2016 Mar;55(3):195 Authors: Marc B PMID: 26862922 [PubMed - as supplied by publisher] from #ENT-PubMed via ola Kala on Inoreader http://ift.tt/23YDFnq via IFTTT
T cells targeting multiple tumour-associated antigens in lymphoma
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 49 δευτερόλεπτα
At the 58th American Society of Hematology (ASH) Annual Meeting & Exposition, Catherine Bollard, MBChB, MD, FRACP, FRCPA, from Children’s National Medical Center, Washington, DC, discusses the dev… Author: VJHemOnc Added: 02/10/2016 (Source: Oncology Tube) from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/20NN0zl via IFTTT
Phase 1 trial of CAR T-cell therapy for lymphoma
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 49 δευτερόλεπτα
At the 58th American Society of Hematology (ASH) Annual Meeting & Exposition, Catherine Bollard, MBChB, MD, FRACP, FRCPA, from Children’s National Medical Center, Washington, DC, discusses the ini… Author: VJHemOnc Added: 02/10/2016 (Source: Oncology Tube) from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1muu9X5 via IFTTT
ASH highlights in CLL and lymphoma by Dr Andrew Zelenetz
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 49 δευτερόλεπτα
Andrew Zelenetz, MD, PhD from the Memorial Sloan-Kettering Cancer Center, New York, NY provides an overview of a few new drugs presented at the American Society of Hematology (ASH) 2015 Annual Meeting… Author: VJHemOnc Added: 02/10/2016 (Source: Oncology Tube) from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/20NN0iI via IFTTT
Should Genetic Tests Be Repeated?
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 49 δευτερόλεπτα
Patient Power founder Andrew Schorr visits with Dr. Michael Keating of MD Anderson Cancer Center to ask audience questions about repeat genetic testing. Dr. Keating discusses which tests are essential… Author: P2Professional Added: 02/09/2016 (Source: Oncology Tube) from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1muu71s via IFTTT
Which New Treatments Are Available to Smoldering Myeloma Patients?
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 49 δευτερόλεπτα
Multiple myeloma expert Dr. Robert Orlowski responds to a question from a Patient Power community member related to access to newly approved treatments for smoldering myeloma patients. Listen as Dr. O… Author: P2Professional Added: 02/09/2016 (Source: Oncology Tube) from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/20NMYrl via IFTTT
Are There New MPN Therapies in Development to Decrease Fibrosis?
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 49 δευτερόλεπτα
“Can we interrupt the fibrotic process?” MPN expert Dr. Srdan Verstovsek of MD Anderson Cancer Center explains PRM-151, and how this anti-fibrotic therapy is being used to improve the quality of life … Author: P2Professional Added: 02/09/2016 (Source: Oncology Tube) from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1muu6KZ via IFTTT
Is There Still a Place for Chemo in CLL?
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 49 δευτερόλεπτα
Which CLL patients benefit most from chemotherapy? CLL expert Dr. Nicole Lamanna explains the various therapeutic agents currently in use, who they are for and why. Get email alerts | http://w… Author: P2Professional Added: 02/09/2016 (Source: Oncology Tube) from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1muu6KV via IFTTT
Changing trends in the incidence of juvenile nasopharyngeal angiofibroma: seven decades of experience at King George's Medical University, Lucknow, India
Main ArticleChanging trends in the incidence of juvenile nasopharyngeal angiofibroma: seven decades of experience at King George's Medical University, Lucknow, IndiaA Mishraa1 c1 and S C Mishraa1 a1 Department of Otolaryngology and Head and Neck Surgery, King George's Medical University, Lucknow, India Abstract Background: The occurrence of juvenile nasopharyngeal angiofibroma is reportedly higher in India than in some other parts of the world, and our centre has seen a four-fold increase in its occurrence across seven decades. Methods: This paper reports a retrospective archival analy...περισσότερα »
Assessment of the Clinical Utility of Cervical and Ocular Vestibular Evoked Myogenic Potential Testing in Elderly Patients.
[image: http:--pt.wkhealth.com-pt-pt-core-templa] Related Articles *Assessment of the Clinical Utility of Cervical and Ocular Vestibular Evoked Myogenic Potential Testing in Elderly Patients.* Otol Neurotol. 2015 Aug;36(7):1238-44 Authors: Piker EG, Baloh RW, Witsell DL, Garrison DB, Lee WT Abstract OBJECTIVES: To assess whether patient age or sex was predictive of a bilaterally absent cervical or ocular vestibular evoked myogenic potential (cVEMP or oVEMP). STUDY DESIGN: Retrospective case review. SETTING: Tertiary center. PATIENTS: Patients presenting with normal vestibular tests... περισσότερα »
Early stage squamous cell carcinoma of the lower lip: predictive factors for recurrence.
*Early stage squamous cell carcinoma of the lower lip: predictive factors for recurrence.* J Laryngol Otol. 2016 Feb 10;:1-4 Authors: Ozkul Y, Songu M, Imre A, Tunc E, Ozkul Z, Arslanoglu S, Pinar E, Onal K Abstract OBJECTIVE: This study aimed to evaluate the effect of tumour thickness on other clinicopathological parameters in early stage lower lip squamous cell carcinoma. METHODS: Forty-six consecutive patients with lower lip squamous cell carcinoma were included in the study. Demographic, clinical and pathological data were retrospectively collected. RESULTS: The mean follow-u...περισσότερα »
Sialendoscopy-assisted transfacial surgery for the removal of an iatrogenic foreign body in Stensen's duct: a stone and broken wire basket.
*Sialendoscopy-assisted transfacial surgery for the removal of an iatrogenic foreign body in Stensen's duct: a stone and broken wire basket.* J Laryngol Otol. 2016 Feb 10;:1-5 Authors: Capaccio P, Gaffuri M, Torretta S, Pignataro L Abstract BACKGROUND: A foreign body is a rare cause of parotid gland obstructive sialadenitis; intra-oral penetration via Stensen's duct is unusual. The relatively recent introduction of interventional sialendoscopy to treat obstructive sialadenitis has allowed surgeons to adopt a gland-sparing approach by means of miniaturised endoscopes and instrument... περισσότερα »
[Problems breathing through the nose and diplopic images].
*[Problems breathing through the nose and diplopic images].* HNO. 2016 Feb 9; Authors: Rödig H, Guntinas-Lichius O, Bitter T PMID: 26861634 [PubMed - as supplied by publisher] from #ENT-PubMed via ola Kala on Inoreader http://ift.tt/1O4y4jC via IFTTT
Carotid Artery Compression Caused by the Cochlea.
[image: http:--pt.wkhealth.com-pt-pt-core-templa] Related Articles *Carotid Artery Compression Caused by the Cochlea.* Otol Neurotol. 2015 Aug;36(7):1275-8 Authors: Giese D, Rask-Andersen H Abstract HYPOTHESIS: We investigated the possible interference between the human internal carotid artery and the cochlea. BACKGROUND: The cochlea and the internal carotid artery (ICA) are anatomically closely related in the human temporal bone. The intimacy may even result in functional interferences. METHODS: Here, we analyzed 324 human plastic inner ear corrosion casts including the ICA canal... περισσότερα »
Does Coupling and Positioning in Vibroplasty Matter? A Prospective Cohort Study.
[image: http:--pt.wkhealth.com-pt-pt-core-templa] Related Articles *Does Coupling and Positioning in Vibroplasty Matter? A Prospective Cohort Study.* Otol Neurotol. 2015 Aug;36(7):1223-30 Authors: Marino R, Lampacher P, Dittrich G, Tavora-Vieira D, Kuthubutheen J, Rajan GP Abstract OBJECTIVE: Vibroplasty has offered a new modality of hearing rehabilitation in patients with mixed, conductive, and sensorineural hearing loss who cannot wear hearing aids. Potentially, the positioning of the floating mass transducer (FMT) in vibroplasty surgery has a critical effect on hearing output... περισσότερα »
Acute vocal fold hemorrhage after phonosurgery.
Related Articles *Acute vocal fold hemorrhage after phonosurgery.* Ear Nose Throat J. 2014 Jul;93(7):E33 Authors: Portnoy JE, Capo C, Sataloff RT PMID: 25025420 [PubMed - indexed for MEDLINE] from #ENT-PubMed via ola Kala on Inoreader http://ift.tt/1KdjJ9Z via IFTTT
Multiple mandibular fractures. Treatment outlines.
*Multiple mandibular fractures. Treatment outlines.* Minerva Stomatol. 2016 Feb;65(1):54-63 Authors: Elia G, Franco E, Clauser LC Abstract Multiple mandibular comminuted fractures usually occur in high energy traumas. The authors describe the management and treatment of multiple mandibular fractures in a young patient after a suicide attempt. PMID: 26862697 [PubMed - as supplied by publisher] from #ENT-PubMed via ola Kala on Inoreader http://ift.tt/1PnBoKM via IFTTT
Reliability and efficacy of palifermin in prevention and management of oral mucositis in patients with acute lymphoblastic leukemia: a randomized, double-blind controlled clinical trial.
*Reliability and efficacy of palifermin in prevention and management of oral mucositis in patients with acute lymphoblastic leukemia: a randomized, double-blind controlled clinical trial.* Minerva Stomatol. 2016 Feb;65(1):43-53 Authors: Lucchese A, Matarese G, Manuelli M, Ciuffreda C, Bassani L, Isola G, Cordasco G, Gherlone E Abstract BACKGROUND: Myeloablative and hematopoietic stem cells transplantation therapy (HSCT) often acts as side-effect to oral mucositis (OM) with no effective treatment. This randomized-controlled trial analyzed the efficacy of palifermin, administered a...περισσότερα »
Prognostic value of lymph node ratio for locoregional failure in patients with advanced head and neck cancers.
*Prognostic value of lymph node ratio for locoregional failure in patients with advanced head and neck cancers.* Minerva Stomatol. 2016 Feb;65(1):39-42 Authors: Dequanter D, Zouaoui Boudjeltia K, Shahla M, Aubert C, Lothaire P Abstract BACKGROUND: In the current study, the utility of lymph node ratio (LNR) was evaluated as an alternative method for predicting locoregional failure in patients with advanced head and neck cancer. METHODS: Fifty-six patients with oral and (pharyngo)laryngeal squamous cell carcinoma were included. Among those, 48 were males and 8 females, with a mean a...περισσότερα »
Retrospective review of 78 rehabilitated head and neck postoncological patients: a new classification method.
*Retrospective review of 78 rehabilitated head and neck postoncological patients: a new classification method.* Minerva Stomatol. 2016 Feb;65(1):17-38 Authors: Brauner E, Valentini V, Jamshir S, Guarino G, Battisti A, Fadda MT, Pompa G Abstract BACKGROUND: Numerous studies have been published about the prosthetic rehabilitation of the postoncological maxillo-facial patient, but the guidelines that emerge lack a correlation between the anatomical classification of the treated site, which generally is preparatory upon surgery, and the type of prosthetic rehabilitation appropriate t... περισσότερα »
Comparative CBCT evaluation of the efficacy of Nd:YAG laser and K3 rotary system in non-surgical root canal retreatment.
*Comparative CBCT evaluation of the efficacy of Nd:YAG laser and K3 rotary system in non-surgical root canal retreatment.* Minerva Stomatol. 2016 Feb;65(1):11-16 Authors: Samiei M, Ghasemi N, Torab A, Rahimi S, Niknami M, Rikhtegaran S, Purnaghi Azar F, Mehdi Vahid Pakdel S Abstract BACKGROUND: The aim of the present study was to compare the efficacy of Nd:YAG laser and K3 rotary system in the non-surgical root canal retreatment. METHODS: Sixty-one rooted human teeth were divided into two groups of 30 after root canal therapy. In groups 1 and 2 root canal retreatments were carrie... περισσότερα »
Bone regeneration in rat femoral defects after osteotomy with surgical ultrasound.
*Bone regeneration in rat femoral defects after osteotomy with surgical ultrasound.* Minerva Stomatol. 2016 Feb;65(1):1-10 Authors: Bergonse Pereira Pedriali MB, Trevisan W, Goulart DE Andrade F, Menck Sangiorgio JP, Ricardo Pires W, DE Paula Ramos S Abstract To evaluate bone healing after osteotomy by surgical drill (D) and piezoelectric ultrasound (U), Wistar rats were submitted to femoral osteotomy and submitted to histological analysis. After 60 h, slight (83.3%) and moderate (3.4%) inflammatory areas were frequent in the U defects whereas D group presented moderate (33.3%) a...περισσότερα »
Book Review: Endonasal Endoscopic Surgery of Skull Base Tumors: An Interdisciplinary Approach.
*Book Review: Endonasal Endoscopic Surgery of Skull Base Tumors: An Interdisciplinary Approach.* Ann Otol Rhinol Laryngol. 2016 Feb 9; Authors: Abuzeid WM PMID: 26862058 [PubMed - as supplied by publisher] from #ENT-PubMed via ola Kala on Inoreader http://ift.tt/1KdjMm6 via IFTTT
Arachnoid cyst of the Fallopian canal and geniculate ganglion area: our experience of 9 cases.
*Arachnoid cyst of the Fallopian canal and geniculate ganglion area: our experience of 9 cases.* Clin Otolaryngol. 2016 Feb 10; Authors: Sagardoy T, De Mones E, Bonnard D, Darrouzet V, Franco-Vidal V Abstract Arachnoid cyst of the Fallopian canal should be suspected and sought in all cases of CSF leak or bacterial meningitis (especially Streptococcus pneumonia, Haemophilus influenzae) in overweight middle-aged women without any osteo-meningeal breach identified on the tegmen tympani. A combination of CT scan and MRI allows the diagnosis of arachnoid cyst of the Fallopian canal, c...περισσότερα »
Hyaluronic acid liposomal gel sustains delivery of a corticoid to the inner ear.
*Hyaluronic acid liposomal gel sustains delivery of a corticoid to the inner ear.* J Control Release. 2016 Feb 6; Authors: El Kechai N, Mamelle E, Nguyen Y, Huang N, Nicolas V, Chaminade P, Yen-Nicolaÿ S, Gueutin C, Granger B, Ferrary E, Agnely F, Bochot A Abstract The inner ear is one of the most challenging organs for drug delivery, mainly because of the blood-perilymph barrier. Therefore, local rather than systemic drug delivery methods are being developed for inner ear therapy. In this work, we have evaluated the benefit of a hyaluronic acid liposomal gel for sustained delive... περισσότερα »
Neuroendocrine carcinoma of the larynx with metastasis to the eyelid.
*Neuroendocrine carcinoma of the larynx with metastasis to the eyelid.* J Community Support Oncol. 2015 Oct;13(10):378-380 Authors: Assi HA, Patel R, Mehdi S Abstract Neuroendocrine tumors are a rare type of neoplasms that comprise only 0.5% of all malignancies.¹ They usually arise from the gastrointestinal tract and the lung.¹,² Neuroendocrine carcinoma of the head and neck is a relatively rare malignancy described in the literature. The larynx is the most commonly affected region of the head and neck.³,⁴ Nevertheless, small-cell carcinoma comprises only 0.5% of all laryngeal can... περισσότερα »
Antagonistic Effects of Insulin and TGF-β3 during Chondrogenic Differentiation of Human BMSCs under a Minimal Amount of Factors
Alexandros G. SfakianakisστοCell and Tissue Research by Alexandros G. SfakianakisΠριν από 52 δευτερόλεπτα
Growth factors are crucial regulators of cell differentiation towards tissue and organ development. Insulin and transforming growth factor-β (TGF-β) have been used as the major factors for chondrogenesis in vitro, by activating the AKT and Smad signaling pathways. Previous reports demonstrated that AKT and Smad3 have a direct interaction that results in the inhibition of TGF-β-mediated cellular responses. However, the result of this interaction between AKT and Smad3 during the chondrogenesis of human bone marrow-derived stem/progenitor cells (hBMSCs) is unknown. In this study, we ...περισσότερα »
Can a Tubal Pregnancy Be Cured or Prevented?
Are you a victim of Tubal Pregnancy? Do you have awareness about this type of pregnancy condition or have you undergone certain tests to confirm that you pregnancy is normal? The day you decide that you want to have child is one of the most important days of your married lives due to the fact that welcoming a baby into this world is not an easy task it requires you to undergo immense pain & stress especially if you are new to this condition. Initially you will worry as to whether you can conceive a baby or not, questions like you might be suffering from infertility problems or you ... περισσότερα »
Morphometric study of the two fused primary ossification centers of the clavicle in the human fetus.
*Morphometric study of the two fused primary ossification centers of the clavicle in the human fetus.* Surg Radiol Anat. 2016 Feb 9; Authors: Baumgart M, Wiśniewski M, Grzonkowska M, Badura M, Dombek M, Małkowski B, Szpinda M Abstract PURPOSES: A satisfactory understanding of the clavicle development may be contributing to both the diagnosis of its congenital defects and prevention of perinatal damage to the shoulder girdle. This study was carried out to examine the transverse and sagittal diameters, cross-sectional area and volume of the two fused primary ossification centers of...περισσότερα »
An undetected common renal arterial trunk: surgical consequences and morbidity analysis.
*An undetected common renal arterial trunk: surgical consequences and morbidity analysis.* Surg Radiol Anat. 2016 Feb 9; Authors: Buisman WJ, Ünlü Ç, de Boer SW, Bos WJ, Nieuwenhuijs JL, Wille J Abstract We present a patient with a recurrent precaval left renal artery, stemming from a right-sided common trunk renal artery. The patient was a 44-year male who presented with a post-traumatic grade IV renal injury. After 3 months without renal function improvement and repeated urinary tract infection, a laparoscopic nephrectomy of the affected right kidney was performed, without upfr... περισσότερα »
Cadaveric study of anterior and posterior elbow endoscopy portals for endoscopic distal biceps repair: comparative anatomy-at-risk.
*Cadaveric study of anterior and posterior elbow endoscopy portals for endoscopic distal biceps repair: comparative anatomy-at-risk.* Surg Radiol Anat. 2016 Feb 9; Authors: Bhatia DN, DasGupta B, Panjwani T Abstract PURPOSE: The purpose of this study was to describe neurovascular structures-at-risk during establishment of five portals for access to distal biceps tendon (DBT) in cubital fossa, and to establish relative safety of these portal sites for such access. We hypothesized that all five portals are safe for endoscopic DBT exploration. METHODS: Ten fresh frozen cadaveric elbo...περισσότερα »
Epidemiological, clinical and laboratory profile of cutaneous polyarteritis nodosa patients: Report of 22 cases and literature review
Publication date: Available online 11 February 2016 *Source:*Autoimmunity Reviews Author(s): Paulo Ricardo Criado, Gabriela Franco Marques, Thamara Cristiane Alves Batista Morita, Jozélio Freire de Carvalho Cutaneous polyarteritis nodosa (CPAN) is a rare disease that affects small and middle caliber vessels of the deep dermis and subcutaneous tissue and its etiopathology remains yet to be understood. Methods: Retrospective review of twenty two cases diagnosed as CPAN and confirmed by skin biopsy over the last 11years was evaluated in our department. Results: We found predominance in...περισσότερα »
The adenomatoid odontogenic tumour: an update of selected issues
The aim of this update was to present the recent notable progress within remaining questions relating to the adenomatoid odontogenic tumour (AOT). Selected issues that were studied included the following: (i) AOT history and terminology, (ii) the so-called peripheral AOT, (iii) AOT and the gubernaculum dentis and (iv) the so-called adenomatoid odontogenic cyst (AOC). The earliest irrefutable European case of AOT was described in 1915 by Harbitz as 'cystic adamantoma'. Recently, Ide et al. have traced two Japanese cases with irrefutable proof described by Nakayama in 1903. The so-... περισσότερα »
Defining the medial-lateral axis of an anatomical femur coordinate system using freehand 3D ultrasound imaging
Publication date: Available online 10 February 2016 Source:Gait & Posture Author(s): Elyse Passmore, Morgan Sangeux Hip rotation from gait analysis informs clinical decisions regarding correct of femoral torsional deformities. However, it is among the least repeatable due to discrepancies in determining the medial-lateral axis of the femur. Conventional or functional calibration methods may be used… Continue reading Defining the medial-lateral axis of an anatomical femur coordinate system using freehand 3D ultrasound imaging
Age-independent and age-dependent sex differences in gait pattern determined by principal component analysis
Publication date: Available online 11 February 2016 Source:Gait & Posture Author(s): Yoshiyuki Kobayashi, Hiroaki Hobara, Thijs A. Heldoorn, Makiko Kouchi, Masaaki Mochimaru Although various studies have reported significant sex differences in pelvic and/or hip-joint motion during normal walking in healthy adults, it is still unclear whether such differences are among the most dominant age-independent sex… Continue reading Age-independent and age-dependent sex differences in gait pattern determined by principal component analysis
Whole-brain grey matter density predicts balance stability irrespective of age and protects older adults from falling
Publication date: March 2016 Source:Gait & Posture, Volume 45 Author(s): Matthieu P. Boisgontier, Boris Cheval, Peter van Ruitenbeek, Oron Levin, Olivier Renaud, Julien Chanal, Stephan P. Swinnen Functional and structural imaging studies have demonstrated the involvement of the brain in balance control. Nevertheless, how decisive grey matter density and white matter microstructural organisation are in… Continue reading Whole-brain grey matter density predicts balance stability irrespective of age and protects older adults from falling
Identification of trunk and pelvis movement compensations in patients with transtibial amputation using angular momentum separation
Publication date: March 2016 Source:Gait & Posture, Volume 45 Author(s): Brecca M. Gaffney, Amanda M. Murray, Cory L. Christiansen, Bradley S. Davidson Patients with unilateral dysvascular transtibial amputation (TTA) have a higher risk of developing low back pain than their healthy counterparts, which may be related to movement compensations used in the absence of ankle… Continue reading Identification of trunk and pelvis movement compensations in patients with transtibial amputation using angular momentum separation
Defining the medial-lateral axis of an anatomical femur coordinate system using freehand 3D ultrasound imaging
Publication date: Available online 10 February 2016 Source:Gait & Posture Author(s): Elyse Passmore, Morgan Sangeux Hip rotation from gait analysis informs clinical decisions regarding correct of femoral torsional deformities. However, it is among the least repeatable due to discrepancies in determining the medial-lateral axis of the femur. Conventional or functional calibration methods may be used… Continue reading Defining the medial-lateral axis of an anatomical femur coordinate system using freehand 3D ultrasound imaging
Are flexible flat feet associated with proximal joint problems in children?
Publication date: Available online 11 February 2016 Source:Gait & Posture Author(s): A. Kothari, P.C. Dixon, J. Stebbins, A.B. Zavatsky, T. Theologis The role of flexible flat feet (FF) in the development of musculoskeletal symptoms at joints proximal to the ankle is unclear. We undertook an observational study to investigate the relationship between foot posture and… Continue reading Are flexible flat feet associated with proximal joint problems in children?
Age-independent and age-dependent sex differences in gait pattern determined by principal component analysis
Publication date: Available online 11 February 2016 Source:Gait & Posture Author(s): Yoshiyuki Kobayashi, Hiroaki Hobara, Thijs A. Heldoorn, Makiko Kouchi, Masaaki Mochimaru Although various studies have reported significant sex differences in pelvic and/or hip-joint motion during normal walking in healthy adults, it is still unclear whether such differences are among the most dominant age-independent sex… Continue reading Age-independent and age-dependent sex differences in gait pattern determined by principal component analysis
The controversial p.Met34Thr variant in GJB2 gene: Two siblings, one genotype, two phenotypes.
Related Articles The controversial p.Met34Thr variant in GJB2 gene: Two siblings, one genotype, two phenotypes. Int J Pediatr Otorhinolaryngol. 2015 Aug;79(8):1316-9 Authors: Lameiras AR, Gonçalves AC, Santos R, O’Neill A, Reis LR, Matos TD, Fialho G, Caria H, Escada P Abstract INTRODUCTION: Recent advances in molecular genetics have increased the identification of genes and mutations… Continue reading The controversial p.Met34Thr variant in GJB2 gene: Two siblings, one genotype, two phenotypes.
Whole-brain grey matter density predicts balance stability irrespective of age and protects older adults from falling
Publication date: March 2016 Source:Gait & Posture, Volume 45 Author(s): Matthieu P. Boisgontier, Boris Cheval, Peter van Ruitenbeek, Oron Levin, Olivier Renaud, Julien Chanal, Stephan P. Swinnen Functional and structural imaging studies have demonstrated the involvement of the brain in balance control. Nevertheless, how decisive grey matter density and white matter microstructural organisation are in… Continue reading Whole-brain grey matter density predicts balance stability irrespective of age and protects older adults from falling
Identification of trunk and pelvis movement compensations in patients with transtibial amputation using angular momentum separation
Publication date: March 2016 Source:Gait & Posture, Volume 45 Author(s): Brecca M. Gaffney, Amanda M. Murray, Cory L. Christiansen, Bradley S. Davidson Patients with unilateral dysvascular transtibial amputation (TTA) have a higher risk of developing low back pain than their healthy counterparts, which may be related to movement compensations used in the absence of ankle… Continue reading Identification of trunk and pelvis movement compensations in patients with transtibial amputation using angular momentum separation
Distinct lymphocyte antigens 6 (Ly6) family members Ly6D, Ly6E, Ly6K and Ly6H drive tumorigenesis and clinical outcome.
*Distinct lymphocyte antigens 6 (Ly6) family members Ly6D, Ly6E, Ly6K and Ly6H drive tumorigenesis and clinical outcome.* Oncotarget. 2016 Feb 3; Authors: Luo L, McGarvey P, Madhavan S, Kumar R, Gusev Y, Upadhyay G Abstract Stem cell antigen-1 (Sca-1) is used to isolate and characterize tumor initiating cell populations from tumors of various murine models [1]. Sca-1 induced disruption of TGF-β signaling is required in vivo tumorigenesis in breast cancer models [2, 3-5]. The role of human Ly6 gene family is only beginning to be appreciated in recent literature [6-9]. To study the ...περισσότερα »
Cutaneous Leishmaniasis: An Overlooked Etiology of Midfacial Destructive Lesions.
*Cutaneous Leishmaniasis: An Overlooked Etiology of Midfacial Destructive Lesions.* PLoS Negl Trop Dis. 2016 Feb;10(2):e0004426 Authors: Alam E, Abbas O, Moukarbel R, Khalifeh I Abstract BACKGROUND: Midline destructive lesions of the face (MDL) have a wide range of etiologies. Cutaneous Leishmaniasis (CL) is rarely reported as a possible cause. METHODS: Fifteen patients with solitary nasal lesions caused by CL were studied. The clinical data, biopsies/scrapings and PCR were collected/performed. Ridley's Pattern (RP) and Parasitic Index (PI) were documented. RESULTS: Patients' age... περισσότερα »
Prognostic value of lymph node ratio for locoregional failure in patients with advanced head and neck cancers.
*Prognostic value of lymph node ratio for locoregional failure in patients with advanced head and neck cancers.* Minerva Stomatol. 2016 Feb;65(1):39-42 Authors: Dequanter D, Zouaoui Boudjeltia K, Shahla M, Aubert C, Lothaire P Abstract BACKGROUND: In the current study, the utility of lymph node ratio (LNR) was evaluated as an alternative method for predicting locoregional failure in patients with advanced head and neck cancer. METHODS: Fifty-six patients with oral and (pharyngo)laryngeal squamous cell carcinoma were included. Among those, 48 were males and 8 females, with a mean a...περισσότερα »
Retrospective review of 78 rehabilitated head and neck postoncological patients: a new classification method.
*Retrospective review of 78 rehabilitated head and neck postoncological patients: a new classification method.* Minerva Stomatol. 2016 Feb;65(1):17-38 Authors: Brauner E, Valentini V, Jamshir S, Guarino G, Battisti A, Fadda MT, Pompa G Abstract BACKGROUND: Numerous studies have been published about the prosthetic rehabilitation of the postoncological maxillo-facial patient, but the guidelines that emerge lack a correlation between the anatomical classification of the treated site, which generally is preparatory upon surgery, and the type of prosthetic rehabilitation appropriate t... περισσότερα »
Precision diagnosis and antidiastole on supernumerary cusp of tooth by CBCT.
*Precision diagnosis and antidiastole on supernumerary cusp of tooth by CBCT.* Surg Radiol Anat. 2016 Feb 9; Authors: Jiang K, Che C, Ding Z, Zeng S, Wang W, He X Abstract PURPOSE: Based on a case of supernumerary cusp on the bucca of left maxillary second molar diagnosed by cone beam computed tomography (CBCT), its genesis, diagnosis and antidiastole are to be analysed. The clinic implication of CBCT is correspondingly discussed. METHODS: The supernumerary cusp was diagnosed by oral general examination, intra-oral radiograph and CBCT. The features of supernumerary cusp, fused to... περισσότερα »
Neuroendocrine carcinoma of the larynx with metastasis to the eyelid.
*Neuroendocrine carcinoma of the larynx with metastasis to the eyelid.* J Community Support Oncol. 2015 Oct;13(10):378-380 Authors: Assi HA, Patel R, Mehdi S Abstract Neuroendocrine tumors are a rare type of neoplasms that comprise only 0.5% of all malignancies.¹ They usually arise from the gastrointestinal tract and the lung.¹,² Neuroendocrine carcinoma of the head and neck is a relatively rare malignancy described in the literature. The larynx is the most commonly affected region of the head and neck.³,⁴ Nevertheless, small-cell carcinoma comprises only 0.5% of all laryngeal can... περισσότερα »
Margin to tumor thickness ratio - A predictor of local recurrence and survival in oral squamous cell carcinoma.
*Margin to tumor thickness ratio - A predictor of local recurrence and survival in oral squamous cell carcinoma.* Oral Oncol. 2016 Feb 6; Authors: Heiduschka G, Virk SA, Palme CE, Ch'ng S, Elliot M, Gupta R, Clark J Abstract OBJECTIVES: To assess whether small oral squamous cell carcinomas (OSCC) require the same margin clearance as large tumors. We evaluated the association between the ratio of the closest margin to tumor size (MSR) and tumor thickness (MTR) with local control and survival. METHODS AND METHODS: The clinicopathologic and follow up data were obtained for 501 OSCC ...περισσότερα »
Human Lung Fibroblasts Inhibit Non-Small Cell Lung Cancer Metastasis in Ex Vivo 4D Model.
[image: http:--linkinghub.elsevier.com-ihub-imag] Related Articles *Human Lung Fibroblasts Inhibit Non-Small Cell Lung Cancer Metastasis in Ex Vivo 4D Model.* Ann Thorac Surg. 2015 Oct;100(4):1167-74; discussion 1174 Authors: Mishra DK, Compean SD, Thrall MJ, Liu X, Massarelli E, Kurie JM, Kim MP Abstract BACKGROUND: We determined the effect of human lung fibroblasts (LFs) in metastatic lesion formation in a four-dimensional (4D) lung cancer model. METHODS: Human cancer-associated fibroblasts (CAFs) were isolated from the primary tumor, and normal LFs were isolated from adjacent l... περισσότερα »
upper respiratory tract infection; +38 new citations
38 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: *upper respiratory tract infection* These pubmed results were generated on 2016/02/11 PubMed comprises more than 24 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites. from #PubMed 2 via ola Kala on Inoreader http://ift.tt/1SK1uMk via IFTTT
Whole-brain grey matter density predicts balance stability irrespective of age and protects older adults from falling
Publication date: March 2016 *Source:*Gait & Posture, Volume 45 Author(s): Matthieu P. Boisgontier, Boris Cheval, Peter van Ruitenbeek, Oron Levin, Olivier Renaud, Julien Chanal, Stephan P. Swinnen Functional and structural imaging studies have demonstrated the involvement of the brain in balance control. Nevertheless, how decisive grey matter density and white matter microstructural organisation are in predicting balance stability, and especially when linked to the effects of ageing, remains unclear. Standing balance was tested on a platform moving at different frequencies and ampl...περισσότερα »
Identification of trunk and pelvis movement compensations in patients with transtibial amputation using angular momentum separation
Publication date: March 2016 *Source:*Gait & Posture, Volume 45 Author(s): Brecca M. Gaffney, Amanda M. Murray, Cory L. Christiansen, Bradley S. Davidson Patients with unilateral dysvascular transtibial amputation (TTA) have a higher risk of developing low back pain than their healthy counterparts, which may be related to movement compensations used in the absence of ankle function. Assessing components of segmental angular momentum provides a unique framework to identify and interpret these movement compensations alongside traditional observational analyses. Angular momentum separa... περισσότερα »
Are flexible flat feet associated with proximal joint problems in children?
Publication date: Available online 11 February 2016 *Source:*Gait & Posture Author(s): A. Kothari, P.C. Dixon, J. Stebbins, A.B. Zavatsky, T. Theologis The role of flexible flat feet (FF) in the development of musculoskeletal symptoms at joints proximal to the ankle is unclear. We undertook an observational study to investigate the relationship between foot posture and the proximal joints in children. It was hypothesised that reduced arch height would be associated with proximal joint symptoms and altered gait kinematics and kinetics particularly in the transverse plane at the hip an... περισσότερα »
The effect of fluctuating maskers on speech understanding of high-performing cochlear implant users
10.3109/14992027.2015.1128124<br>Stefan Zirn from #Audiology via ola Kala on Inoreader http://ift.tt/1KHng0h via IFTTT
Application of PEG-400 as a green biodegradable polymeric medium for the catalyst-free synthesis of spiro-dihydropyridines and their use as acetyl and butyrylcholinesterase inhibitors
Publication date: Available online 10 February 2016 *Source:*Bioorganic & Medicinal Chemistry Author(s): Ammar Maryamabadi, Alireza Hasaninejad, Najmeh Nowrouzi, Gholamhossein Mohebbi, Behvar Asghari A simple, efficient and green approach for the synthesis of spiro-dihydropyridines derivatives by one-pot multi-component reaction of isatin or acenaphthoquinone derivatives(1 eq) with malononitrile (1 eq) and N,N'-substituted-2-nitroethene-1,1-diamines(1 eq) in PEG-400 under catalyst-free conditions is described. This method provides several advantages such as environmental friendlines... περισσότερα »
Identification of Spirooxindole and Dibenzoxazepine Motifs as Potent Mineralocorticoid Receptor Antagonists
Publication date: Available online 9 February 2016 *Source:*Bioorganic & Medicinal Chemistry Author(s): Stephen D. Lotesta, Andrew P. Marcus, Yajun Zheng, Katerina Leftheris, Paul B. Noto, Shi Meng, Geeta Kandpal, Guozhou Chen, Jing Zhou, Brian McKeever, Yuri Bukhtiyarov, Yi Zhao, Deepak S. Lala, Suresh B. Singh, Gerard M. McGeehan Mineralocorticoid receptor (MR) antagonists continue to be a prevalent area of research in the pharmaceutical industry. Herein we report the discovery of various spirooxindole and dibenzoxazepine constructs as potent MR antagonists. SAR analysis of our sp...περισσότερα »
Synthesis and Biological Evaluation of New Fluorinated and Chlorinated Indenoisoquinoline Topoisomerase I Poisons
Publication date: Available online 9 February 2016 *Source:*Bioorganic & Medicinal Chemistry Author(s): Daniel E. Beck, Wei Lv, Monica Abdelmalak, Caroline B. Plescia, Keli Agama, Christophe Marchand, Yves Pommier, Mark Cushman Fluorine and chlorine are metabolically stable, but generally less active replacements for a nitro group at the 3-position of indenoisoquinoline topoisomerase IB (Top1) poisons. A number of strategies were employed in the present investigation to enhance the Top1 inhibitory potencies and cancer cell growth inhibitory activities of halogenated indenoisoquinoli...περισσότερα »
Cross-resistance to fluconazole induced by exposure to the agricultural azole tetraconazole: an environmental resistance school?
Summary This study aimed to investigate the influence of tetraconazole and malathion, both used in agricultural activities, on resistance to fluconazole, itraconazole and voriconazole in *Candida parapsilosis* ATCC 22019. The susceptibility to tetraconazole, malathion, fluconazole, itraconazole and voriconazole, through broth microdilution. Then, 12 independent replicates, were separated and exposed to four treatment groups, each one containing three replicates: G1: tetraconazole; G2: malathion; G3: fluconazole (positive control); G4: negative control. Replicates from G1, G2 and G... περισσότερα »
The influence of intensive care unit-acquired central line-associated bloodstream infection on in-hospital mortality: A single-center risk-adjusted analysis
Publication date: Available online 10 February 2016 *Source:*American Journal of Infection Control Author(s): S.W. Wong, D. Gantner, S. McGloughlin, T. Leong, L.J. Worth, G. Klintworth, C. Scheinkestel, D. Pilcher, A.C. Cheng, A.A. Udy ObjectiveTo explore the risk-adjusted association between intensive care unit (ICU)-acquired central line-associated bloodstream infection (CLABSI) and in-hospital mortality.DesignRetrospective observational study.SettingForty-five-bed adult ICU.PatientsAll non-extracorporeal membrane oxygenation ICU admissions between July 1, 2008, and April 30, 2014...περισσότερα »
Successful development of a direct observation program to measure health care worker hand hygiene using multiple trained volunteers
Publication date: Available online 10 February 2016 *Source:*American Journal of Infection Control Author(s): W. Matthew Linam, Michele D. Honeycutt, Craig H. Gilliam, Christy M. Wisdom, Shasha Bai, Jayant K. Deshpande BackgroundDirect observation of health care worker (HCW) hand hygiene (HH) remains the gold standard, but implementation is challenging. Our objective was to develop an accurate HH observation program using multiple HCW volunteers.MethodsHH compliance was defined as correct HH performed before and after contact with a patient or a patient's environment. HCW volunteers ...περισσότερα »
A systematic approach for developing a ventilator-associated pneumonia prevention bundle
Publication date: Available online 10 February 2016 *Source:*American Journal of Infection Control Author(s): Kathleen Speck, Nishi Rawat, Noah C. Weiner, Haddis G. Tujuba, Donna Farley, Sean Berenholtz BackgroundVentilator-associated pneumonia (VAP) is among the most common type of health care–associated infection in the intensive care unit and is associated with significant morbidity and mortality. Existing VAP prevention intervention bundles vary widely on the interventions included and in the approaches used to develop these bundles. The objective of this study was to develop a ...περισσότερα »
Occupational exposure to infection risk and use of personal protective equipment by emergency medical personnel in the Republic of Korea
Publication date: Available online 10 February 2016 *Source:*American Journal of Infection Control Author(s): Hyang Soon Oh, Dongchoon Uhm BackgroundFew studies of occupational exposure (OE) to infectious risk among emergency medical personnel (EMP) or their use of personal protective equipment (PPE) have been conducted in the Republic of Korea.ObjectiveTo determine the status of OE to infectious risks and use of PPE.MethodsA convenience sample of 907 questionnaires (response rate, 88.5%) was collected from September 1, 2014, to January 31, 2015, in 5 metropolitan Korean cities.Resu... περισσότερα »
Utility of a single nasal polymerase chain reaction assay in predicting absence of skin and environmental contamination in hospitalized patients with past methicillin-resistant Staphylococcus aureus
Publication date: Available online 10 February 2016 *Source:*American Journal of Infection Control Author(s): Dubert M. Guerrero, Matthew Wagner, Grace Carson, Christine Hanish, Jody Thompson, Megan Orr, Felix Roth, Paul J. Carson We evaluated hospitalized patients with a history of methicillin-resistant Staphylococcus aureus (MRSA) for persistent colonization and need for contact precautions. Up to 3 daily cultures of nares, skin, and any present wounds were compared with a single nasal polymerase chain reaction (PCR) assay. Most patients (76.2%) were no longer colonized with MRSA. ...περισσότερα »
Pre and post radiotherapy serum oxidant/antioxidant status in breast cancer patients: Impact of age, BMI and clinical stage of the disease
Publication date: May–June 2016 *Source:*Reports of Practical Oncology & Radiotherapy, Volume 21, Issue 3 Author(s): Maryam Khalil Arjmandi, Dariush Moslemi, Azadeh Sadati Zarrini, Maryam Ebrahimnezhad Gorji, Abbas Mosapour, Asefeh Haghhaghighi, Sohrab Halalkhor, Ali Bijani, Hadi Parsian AimIn this study the effects of radiation therapy (RT) on serum oxidant/antioxidant status in breast cancer patients and the impact of age, BMI and clinical stage of the disease on the aforementioned variables were investigated.BackgroundRT that is used for cancer treatment is dependent on the produ... περισσότερα »
Interference of functional monomers with polymerization efficiency of adhesives
The degree of conversion (DC) of camphorquinone/amine-based adhesives is affected by acidic functional monomers as a result of inactivation of the amine co-initiator through an acid–base reaction. During bonding, functional monomers of self-etch adhesives chemically interact with hydroxyapatite (HAp). Here, we tested in how far the latter interaction of functional monomers with HAp counteracts the expected reduction in DC of camphorquinone/amine-based adhesives. The DC of three experimental adhesive formulations, containing either of the two functional monomers [10-methacryloylox... περισσότερα »
Interference of functional monomers with polymerization efficiency of adhesives
The degree of conversion (DC) of camphorquinone/amine-based adhesives is affected by acidic functional monomers as a result of inactivation of the amine co-initiator through an acid–base reaction. During bonding, functional monomers of self-etch adhesives chemically interact with hydroxyapatite (HAp). Here, we tested in how far the latter interaction of functional monomers with HAp counteracts the expected reduction in DC of camphorquinone/amine-based adhesives. The DC of three experimental adhesive formulations, containing either of the two functional monomers [10-methacryloylox... περισσότερα »
Antagonistic Effects of Insulin and TGF-β3 during Chondrogenic Differentiation of Human BMSCs under a Minimal Amount of Factors
Growth factors are crucial regulators of cell differentiation towards tissue and organ development. Insulin and transforming growth factor-β (TGF-β) have been used as the major factors for chondrogenesis in vitro, by activating the AKT and Smad signaling pathways. Previous reports demonstrated that AKT and Smad3 have a direct interaction that results in the inhibition of TGF-β-mediated cellular responses. However, the result of this interaction between AKT and Smad3 during the chondrogenesis of human bone marrow-derived stem/progenitor cells (hBMSCs) is unknown. In this study, we ...περισσότερα »
Cranio-facial remodeling in domestic dogs is associated with changes in larynx position
Abstract The hyo-laryngeal complex is a multi-segmented structure integrating the oral and pharyngeal cavities and thus a variety of critical functions related to airway control, feeding, and vocal communication. Currently, we lack a complete understanding of how the hyoid complex, and the functions it mediates, can also be affected by changes in surrounding cranio-facial dimensions. Here, we explore these relationships in a breed of domestic dog, the Portuguese Water Dog, which is characterized by strong cranio-facial variation. We used radiographic images of the upper body and h...περισσότερα »
An update on sputum MicroRNAs in lung cancer diagnosis
Lung cancer is one of the leading cause of cancer mortality in the world. It is well known that genetic damages could result in lung tumor genesis. Despite years of research, the survival rate of the patients has not been markedly improved. According to lack of high sensitivity and specificity in diagnostic tests, just about 15–20% of lung cancer cases are discovered prior to progression of the disease. In last decade, sputum biomarkers have been developed for early detection/diagnosis of lung cancer. MicroRNAs are a class of small endogenous noncoding RNAs, which act as post-tra...περισσότερα »
Prognostic value of lymph node ratio for locoregional failure in patients with advanced head and neck cancers.
*Prognostic value of lymph node ratio for locoregional failure in patients with advanced head and neck cancers.* Minerva Stomatol. 2016 Feb;65(1):39-42 Authors: Dequanter D, Zouaoui Boudjeltia K, Shahla M, Aubert C, Lothaire P Abstract BACKGROUND: In the current study, the utility of lymph node ratio (LNR) was evaluated as an alternative method for predicting locoregional failure in patients with advanced head and neck cancer. METHODS: Fifty-six patients with oral and (pharyngo)laryngeal squamous cell carcinoma were included. Among those, 48 were males and 8 females, with a mean a...περισσότερα »
Factors predicting early diagnosis of pediatric laryngotracheobronchial foreign bodies.
*Factors predicting early diagnosis of pediatric laryngotracheobronchial foreign bodies.* Otolaryngol Pol. 2015 Dec 31;69(6):45-52 Authors: Nirmal NS, Parida P, Gopalakrishnan S, Saxena SK Abstract OBJECTIVE: To study the clinical and radiological findings to make early diagnosis of foreign body (FB) aspiration in children Methods: This prospective study was conducted on 45 children below 12 years of age with a clinical diagnosis of FB aspiration undergone rigid bronchoscopy from September 2008 to may 2010. RESULTS: Bronchoscopy was positive for FB in 37 children. The results of ...περισσότερα »
Intralesional cidofovir injection for recurrent respiratory papillomatosis in Japan.
*Intralesional cidofovir injection for recurrent respiratory papillomatosis in Japan.* Auris Nasus Larynx. 2016 Feb 6; Authors: Murono S, Nakanishi Y, Tsuji A, Endo K, Kondo S, Wakisaka N, Yoshizaki T Abstract OBJECTIVE: The treatment of recurrent respiratory papillomatosis (RRP) continues to be difficult. Adjuvant pharmacological treatment is increasingly being used, and intralesional cidofovir injection remains the leading option. Almost all papers regarding the treatment come from the United States and Europe. The present study demonstrated it for the first time from Asia. ME... περισσότερα »
Cavernous sinus thrombosis secondary to aspergillus granuloma: A case report and review of the literature.
*Cavernous sinus thrombosis secondary to aspergillus granuloma: A case report and review of the literature.* Auris Nasus Larynx. 2016 Feb 6; Authors: Brenet E, Boulagnon-Rombi C, N'guyen Y, Litré CF Abstract Cavernous sinus thrombosis is a rare but serious complication of sphenoid aspergillosis. The rarity of this pathology makes its diagnostic very difficult on a clinical, biological and radiological sense. The authors present a case of cavernous sinus thrombosis with ipsilateral internal carotid artery thrombosis secondary to a non-invasive sphenoid aspergillosis in an immunoco... περισσότερα »
Einsatzgebiete und Verfahren der Vaginal Rejuvenation
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Intimchirurgische Eingriffe Die ästhetische Intimchirurgie als bloße Lifestyle-Intervention zu sehen, greift zu kurz. Die chirurgische Tätigkeit in dieser Körperregion verlangt ein detailliertes Wissen um die Anatomie, eine gezielte Indikationsstellung und eine fundierte operative Erfahrung. from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1SiNqsG via IFTTT
Lesion length of optic neuritis impacts visual prognosis in neuromyelitis optica
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
The visual acuity prognoses of patients with neuromyelitis optica (NMO) are worse than those with optic neuritis (ON) caused by other diseases. Predicting the prognoses of ON at the time of onset is important for selecting treatments for NMO patients. (Source: Journal of Neuroimmunology) from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1SiNqca via IFTTT
PGE released by primary sensory neurons modulates Toll-like receptor 4 activities through an EP receptor-dependent process
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Exogenous prostaglandin E2 (PGE2) displays mixed regulatory properties with regard to inflammatory gene expression in dorsal root ganglion (DRG) cells. We show here that endogenously-produced nanomolar concentrations of PGE2, such as that generated in response to Toll-like receptor 4 (TLR4) stimulation, inhibits both cyclooxygenase-2 (COX-2) and tumour necrosis factor alpha (TNFα) mRNA expression in DRG […]
A retrospective analysis of possible triggers of Guillain–Barre syndrome
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
In conclusion, this study has shown that prior infection, surgery, trauma and ganglioside may be clinical contributors to the onset of GBS and raised the possibility that they may act synergistically as triggers for the development of GBS. (Source: Journal of Neuroimmunology) from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1SiNn05 via IFTTT
Association of ICAM-1 (K469E) and MCP-1 −2518 A>G gene polymorphism with brain abscess
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Brain abscess develops in response to a parenchymal infection. Intercellular adhesion molecule-1 (ICAM-1) and monocyte chemoattractant protein-1 (MCP-1) play vital role in central nervous system (CNS) diseases. We studied ICAM-1 (K469E) and MCP-1 (−2518 A>G) polymorphisms among brain abscess patients. The genotypic distributions of ICAM-1 (K469E) and MCP-1 (−2518 A>G) were significantly different between patients […]
Mom’s Exposure to Car Smog May Up Child’s Asthma Risk (CME/CE)
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
(MedPage Today) — More asthma seen in children whose mothers lived near highways (Source: MedPage Today Allergy) from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1SiNmcx via IFTTT
Adaptation of the inflammatory immune response across pregnancy and postpartum in Black and White women
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
(Source: Journal of Reproductive Immunology) from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1muoe4h via IFTTT
Acute vocal fold hemorrhage after phonosurgery.
Related Articles Acute vocal fold hemorrhage after phonosurgery. Ear Nose Throat J. 2014 Jul;93(7):E33 Authors: Portnoy JE, Capo C, Sataloff RT PMID: 25025420 [PubMed – indexed for MEDLINE] from Head and Neck on PubMed via xlomafota13 on Inoreader http://ift.tt/1KdjJ9Z via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1XkV7Ox via IFTTT
Cross-resistance to fluconazole induced by exposure to the agricultural azole tetraconazole: an environmental resistance school?
Summary This study aimed to investigate the influence of tetraconazole and malathion, both used in agricultural activities, on resistance to fluconazole, itraconazole and voriconazole in Candida parapsilosis ATCC 22019. The susceptibility to tetraconazole, malathion, fluconazole, itraconazole and voriconazole, through broth microdilution. Then, 12 independent replicates, were separated and exposed to four treatment groups, each one… Continue reading Cross-resistance to fluconazole induced by exposure to the agricultural azole tetraconazole: an environmental resistance school?
The influence of intensive care unit-acquired central line-associated bloodstream infection on in-hospital mortality: A single-center risk-adjusted analysis
Publication date: Available online 10 February 2016 Source:American Journal of Infection Control Author(s): S.W. Wong, D. Gantner, S. McGloughlin, T. Leong, L.J. Worth, G. Klintworth, C. Scheinkestel, D. Pilcher, A.C. Cheng, A.A. Udy ObjectiveTo explore the risk-adjusted association between intensive care unit (ICU)-acquired central line-associated bloodstream infection (CLABSI) and in-hospital mortality.DesignRetrospective observational study.SettingForty-five-bed adult ICU.PatientsAll… Continue reading The influence of intensive care unit-acquired central line-associated bloodstre... περισσότερα »
Successful development of a direct observation program to measure health care worker hand hygiene using multiple trained volunteers
Publication date: Available online 10 February 2016 Source:American Journal of Infection Control Author(s): W. Matthew Linam, Michele D. Honeycutt, Craig H. Gilliam, Christy M. Wisdom, Shasha Bai, Jayant K. Deshpande BackgroundDirect observation of health care worker (HCW) hand hygiene (HH) remains the gold standard, but implementation is challenging. Our objective was to develop an accurate… Continue reading Successful development of a direct observation program to measure health care worker hand hygiene using multiple trained volunteers
A systematic approach for developing a ventilator-associated pneumonia prevention bundle
Publication date: Available online 10 February 2016 Source:American Journal of Infection Control Author(s): Kathleen Speck, Nishi Rawat, Noah C. Weiner, Haddis G. Tujuba, Donna Farley, Sean Berenholtz BackgroundVentilator-associated pneumonia (VAP) is among the most common type of health care–associated infection in the intensive care unit and is associated with significant morbidity and mortality. Existing VAP… Continue reading A systematic approach for developing a ventilator-associated pneumonia prevention bundle
Mom’s Exposure to Car Smog May Up Child’s Asthma Risk (CME/CE)
(MedPage Today) — More asthma seen in children whose mothers lived near highways (Source: MedPage Today Allergy) from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://ift.tt/1SiNmcx via IFTTT
Safety and Immunogenicity of the Dengue Virus Vaccine TV005 (TetraVax-DV TV005) in Healthy Adults, Adolescents, and Children in Dhaka, Bangladesh
Condition: DengueInterventions: Biological: TV005 vaccine; Biological: PlaceboSponsors: National Institute of Allergy and Infectious Diseases (NIAID); University of Vermont College of Medicine (UVM), Burlington, VT; Johns Hopkins School of Public Health (JHSPH), Baltimore, MDNot yet recruiting – verified February 2016 (Source: ClinicalTrials.gov) MedWorm Sponsor Message: Directory of the best January Sales in the UK. Find the… Continue reading Safety and Immunogenicity of the Dengue Virus Vaccine TV005 (TetraVax-DV TV005) in Healthy Adults, Adolescents, and Children in Dhaka, Bangla... περισσότερα »
Mechanisms Underlying Peanut Allergic Reactions in TRACE Peanut Study Participants: Extension Study
Conditions: Food Hypersensitivity; Peanut HypersensitivityInterventions: Other: DBPCFC to peanut cookie; Other: Single-dose DBPCFCSponsors: Imperial College London; University of Manchester; Food Standards Agency, United Kingdom; Cambridge University Hospitals NHS Foundation TrustNot yet recruiting – verified January 2016 (Source: ClinicalTrials.gov) from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://ift.tt/1LiSPZ3 via IFTTT
Anisakis Blastocystis Cryptosporidium Fish Serology
Conditions: Allergy to Fish; Allergy; AnisakisInterventions: Other: Questionnaire; Biological: Detection of anti-Anisakis and anti-fish antibodiesSponsors: University Hospital, Lille; Institut Pasteur de Lille; ANSES, Boulogne-sur-Mer; Hôpital Cochin; Région Nord-Pas de Calais, FranceRecruiting – verified January 2016 (Source: ClinicalTrials.gov) MedWorm Sponsor Message: Directory of the best January Sales in the UK. Find the best Christmas presents too.… Continue reading Anisakis Blastocystis Cryptosporidium Fish Serology
Skin Tests in Cat Allergic Patients With Cat Dander Samples Obtained Before and After Vaccinating the Cat
Condition: HypersensitivityIntervention: Other: Diagnostic skin testingSponsor: University of ZurichNot yet recruiting – verified January 2016 (Source: ClinicalTrials.gov) MedWorm Sponsor Message: Directory of the best January Sales in the UK. Find the best Christmas presents too. from #Head and Neck by Sfakianakis via simeraentaxei on Inoreader http://ift.tt/1LiSNjX via IFTTT
Book review.
*Book review.* Int J Audiol. 2016 Mar;55(3):196 Authors: Gilbert J PMID: 26862923 [PubMed - as supplied by publisher] from #Audiology via ola Kala on Inoreader http://ift.tt/1QXI8Q6 via IFTTT
Book Review.
*Book Review.* Int J Audiol. 2016 Mar;55(3):195 Authors: Marc B PMID: 26862922 [PubMed - as supplied by publisher] from #Audiology via ola Kala on Inoreader http://ift.tt/23YDFnq via IFTTT
Effect of Radiofrequency Thermal Ablation Treatment on Nasal Ciliary Motility: A Study with Phase-Contrast Microscopy.
Alexandros G. SfakianakisστοRehabilitation,Sports and Exercise Medicine by Alexandros G. SfakianakisΠριν από 1 ώρα
*Effect of Radiofrequency Thermal Ablation Treatment on Nasal Ciliary Motility: A Study with Phase-Contrast Microscopy.* Otolaryngol Head Neck Surg. 2016 Feb 9; Authors: Rosato C, Pagliuca G, Martellucci S, de Vincentiis M, Greco A, Fusconi M, De Virgilio A, Gallipoli C, Simonelli M, Gallo A Abstract OBJECTIVE: To investigate the efficacy of nasal ciliary motility after radiofrequency ablation treatment in patients with isolated inferior turbinate hypertrophy and to clarify how long until normal ciliary function is restored. STUDY DESIGN: Prospective, single-group, pretest-posttes... περισσότερα »
New method of neck surface electromyography for the evaluation of tongue-lifting activity.
Alexandros G. SfakianakisστοRehabilitation,Sports and Exercise Medicine by Alexandros G. SfakianakisΠριν από 1 ώρα
*New method of neck surface electromyography for the evaluation of tongue-lifting activity.* J Oral Rehabil. 2016 Feb 10; Authors: Manda Y, Maeda N, Pan Q, Sugimoto K, Hashimoto Y, Tanaka Y, Kodama N, Minagi S Abstract Elevation of the posterior part of the tongue is important for normal deglutition and speech. The purpose of this study was to develop a new surface electromyography (EMG) method to non-invasively and objectively evaluate activity in the muscles that control lifting movement in the posterior tongue. Neck surface EMG (N-EMG) was recorded using differential surface ... περισσότερα »
True Vertigo Patients in Emergency Department; an Epidemiologic Study.
*True Vertigo Patients in Emergency Department; an Epidemiologic Study.* Emerg (Tehran). 2016;4(1):25-8 Authors: Shahrami A, Norouzi M, Kariman H, Hatamabadi HR, Arhami Dolatabadi A Abstract INTRODUCTION: Vertigo prevalence is estimated to be 1.8% among young adults and more than 30% in the elderly. 13-38% of the referrals of patients over 65 years old in America are due to vertigo. Vertigo does not increase the risk of mortality but it can affect the patient's quality of life. Therefore, this study was designed to evaluate the epidemiologic characteristics of vertigo patients re... περισσότερα »
Features of Residual Dizziness after Canalith Repositioning Procedures for Benign Paroxysmal Positional Vertigo.
*Features of Residual Dizziness after Canalith Repositioning Procedures for Benign Paroxysmal Positional Vertigo.* Otolaryngol Head Neck Surg. 2016 Feb 9; Authors: Martellucci S, Pagliuca G, de Vincentiis M, Greco A, De Virgilio A, Nobili Benedetti FM, Gallipoli C, Rosato C, Clemenzi V, Gallo A Abstract OBJECTIVES: To assess factors related to residual dizziness (RD) in patients who underwent successful canalith repositioning procedures (CRPs) for benign paroxysmal positional vertigo (BPPV). STUDY DESIGN: Prospective cohort study. SETTING: Academic center. SUBJECTS AND METHODS: Nin... περισσότερα »
Diagnostic Value of Clinical Cervical Spine Tests in Patients With Cervicogenic Somatic Tinnitus.
[image: http:--highwire.stanford.edu-icons-exter] Related Articles *Diagnostic Value of Clinical Cervical Spine Tests in Patients With Cervicogenic Somatic Tinnitus.* Phys Ther. 2015 Nov;95(11):1529-35 Authors: Michiels S, Van de Heyning P, Truijen S, De Hertogh W Abstract BACKGROUND: Tinnitus can be related to many different etiologies, such as hearing loss or a noise trauma, but it also can be related to the somatosensory system of the cervical spine. The diagnosis of cervicogenic somatic tinnitus (CST) is made when the predominant feature is the temporal coincidence of appearan...περισσότερα »
Are emergency physicians and paramedics providing canalith repositioning manoeuvre for benign paroxysmal positional vertigo?
[image: http:--media.wiley.com-assets-7315-19-Wi] Related Articles *Are emergency physicians and paramedics providing canalith repositioning manoeuvre for benign paroxysmal positional vertigo?* Emerg Med Australas. 2015 Apr;27(2):179-80 Authors: Bashir K, Qotb MA, Alkahky S, Fathi AM, Mohamed MA, Cameron PA PMID: 25651159 [PubMed - indexed for MEDLINE] from Hearing and Balance via ola Kala on Inoreader http://ift.tt/1o1DeYz via IFTTT
Susceptibility profile and epidemiological cut-off values of Cryptococcus neoformans species complex from Argentina
Summary Epidemiological cut-off values (ECVs) based on minimal inhibitory concentration (MIC) distribution have been recently proposed for some antifungal drug/*Cryptococcus neoformans* combinations. However, these ECVs vary according to the species studied, being serotypes and the geographical origin of strains, variables to be considered. The aims were to define the wild-type (WT) population of the *C. neoformans* species complex (*C. neoformans*) isolated from patients living in Argentina, and to propose ECVs for six antifungal drugs. A total of 707 unique *C. neoformans* isola... περισσότερα »
Pulmonary fungal infections in patients with acute myeloid leukaemia: is it the time to revise the radiological diagnostic criteria?
[image: cover.gif?v=1&s=09d3f8c75474f06ee5ac3319] Summary The definition of pulmonary fungal infections (PFI) according to the EORTC-MSG criteria may lack diagnostic sensitivity due to the possible presentation of PFI with different radiological pictures. We evaluated the hypothesis to apply less restrictive radiological criteria to define PFI in patients with acute myeloid leukaemia (AML) submitted to chemotherapy. Overall, 73 consecutive episodes of pulmonary infiltrates associated to positive serum galactomannan test or fungal isolation or galactomannan detection from respirat...περισσότερα »
Ethanol-metabolizing activities and isozyme protein contents of alcohol and aldehyde dehydrogenases in human liver: phenotypic traits of the ADH1B*2 and ALDH2*2 variant gene alleles.
Objective: Alcohol dehydrogenase (ADH) and aldehyde dehydrogenase (ALDH) are principal enzymes responsible for the metabolism of ethanol. East Asian populations are unique in that they carry both a prevalent ADH1B*2 and a dominant-negative ALDH2*2 allele. A systematic investigation of ethanol-metabolizing activities in normal livers correlated with the corresponding functional allelic variations and protein contents of the relevant isozymes in respective enzyme families has been lacking. Materials and methods: To obtain a reasonable sample size encompassing all possible genetic alle...περισσότερα »
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