Bioabsorbable steroid-eluting sinus implants for in-office treatment of recurrent sinonasal polyposis after sinus surgery: 6-month outcomes from a randomized, controlled, blinded study
RESOLVE: bioabsorbable steroid-eluting sinus implants for in-office treatment of recurrent sinonasal polyposis after sinus surgery: 6-month outcomes from a randomized, controlled, blinded study: Background Patients with recurrent sinonasal polyposis after endoscopic sinus surgery (ESS) have limited treatment options. Safety and efficacy were previously reported for a bioabsorbable sinus implant that elutes mometasone furoate for 3 months. Here we summarize longer-term outcomes. Methods A randomized, controlled, blinded study with 100 chronic rhinosinusitis with nasal polyps (CRSwNP)...περισσότερα »
The International Frontal Sinus Anatomy Classification (IFAC) and Classification of the Extent of Endoscopic Frontal Sinus Surgery (EFSS)
The International Frontal Sinus Anatomy Classification (IFAC) and Classification of the Extent of Endoscopic Frontal Sinus Surgery (EFSS): The frontal recess and frontal sinus anatomy can vary from simple to complex. The variations in the anatomy of the frontal recess and frontal sinus are considerable but almost all variations can be classified if the various cell patterns are analyzed. This consensus document was developed to improve the ability of the surgeon to understand these possible variations, plan the surgery, and communicate these complexities when teaching or reporting ... περισσότερα »
Treating post-burn depigmentation with tiny epidermal particles graft
The clinical experience for treating post-burn depigmentation with tiny epidermal particles graft: Abstract The critical problem of post-burn depigmentation is the lacking normal melanocytes. Auto-skin grafting and autologous non-cultured epidermal cell suspension have been used to improve the appearance. However, a large amount of skin graft is required of donor sites in the former method, while the latter method is thought to be complicated and costly. This study is designed to generalise the experience of tiny epidermal particles graft (TEPG) for treating post-burn depigmentatio... περισσότερα »
What should be the antibiotic prescription protocol for burn patients admitted in the department of burns, plastic and reconstructive surgery
What should be the antibiotic prescription protocol for burn patients admitted in the department of burns, plastic and reconstructive surgery: Abstract This is a prospective study with the aim to determine specific patterns of burn wound bacterial colonisation and antimicrobial resistance profiles. There is a high incidence of infections and septicaemia in post-burn patients, which, in turn, are associated with high morbidity and mortality, a fact that compelled us to undertake this study. The study was conducted over a period 11 months, from 1 August 2014 to 30 June 2015, in 50 bur... περισσότερα »
Povidone-iodine ointment demonstrates in vitro efficacy against biofilm formation
Povidone-iodine ointment demonstrates in vitro efficacy against biofilm formation: Abstract Anti-infectives used to treat chronic exuding wounds are diluted by wound exudates, absorbed into dressings, metabolised by proteases and destroyed by pH. In order to mimic such effects of exudates, the efficacy of six topical wound agents was assessed undiluted and at 10% concentrations, including povidone-iodine ointment and a silver-impregnated wound dressing, to remove biofilms of *Pseudomonas aeruginosa*, multi-species biofilms of *Candida albicans* and methicillin-resistant *Staphyloco...περισσότερα »
Brachial Artery Aneurysm in a 7-Month-Old Infant
Brachial Artery Aneurysm in a 7-Month-Old Infant: Case Report and Literature Review: [image: image] Summary: Congenital upper extremity aneurysms are very rare and can be challenging to diagnose and treat. Although they can present as an isolated finding, they are often associated with other systemic conditions. We present a rare case of brachial artery aneurysm in a 7-month-old boy. The patient was evaluated with ultrasound, magnetic resonance angiography, and vein mapping before surgical reconstruction. After excision of the aneurysm, the brachial artery was reconstructed with an...περισσότερα »
New Frontiers in Promoting TRAIL-Mediated Cell Death: Focus on Natural Sensitizers, miRNAs, and Nanotechnological Advancements.
*New Frontiers in Promoting TRAIL-Mediated Cell Death: Focus on Natural Sensitizers, miRNAs, and Nanotechnological Advancements.* Cell Biochem Biophys. 2016 Mar;74(1):3-10 Authors: Farooqi AA, Gadaleta CD, Ranieri G, Fayyaz S, Marech I Abstract Cancer is a multifaceted and genomically complex disease, and rapidly emerging scientific evidence is emphasizing on intra-tumor heterogeneity within subpopulations of tumor cells and rapidly developing resistance against different molecular therapeutics. There is an overwhelmingly increasing list of agents currently being tested for effica...περισσότερα »
The Preclinical and Clinical Effects of Vilazodone for the Treatment of Major Depressive Disorder.
*The Preclinical and Clinical Effects of Vilazodone for the Treatment of Major Depressive Disorder.* Expert Opin Drug Discov. 2016 Mar 14; Authors: Sahli ZT, Banerjee P, Tarazi FI Abstract INTRODUCTION: Major depressive disorder (MDD) is the leading cause of disability worldwide, and according to the STAR*D trial, only 33% of patients with MDD responded to initial drug therapy. Augmentation of the leading class of antidepressant treatment, selective serotonin reuptake inhibitors (SSRIs), with the 5-HT1A receptor agonist buspirone has been shown to be effective in treating patient... περισσότερα »
The development of high-content screening (HCS) technology and its importance to drug discovery.
*The development of high-content screening (HCS) technology and its importance to drug discovery.* Expert Opin Drug Discov. 2016 Mar 14; Authors: Fraietta I, Gasparri F Abstract INTRODUCTION: High-content screening (HCS) was introduced about twenty years ago as a promising analytical approach to facilitate some critical aspects of drug discovery. Its application has spread progressively within the pharmaceutical industry and academia to the point that it today represents a fundamental tool in supporting drug discovery and development. Areas covered: Here, the authors review some ... περισσότερα »
Prefrontal Ischemia in the Rat Leads to Secondary Damage and Inflammation in Remote Gray and White Matter Regions.
*Prefrontal Ischemia in the Rat Leads to Secondary Damage and Inflammation in Remote Gray and White Matter Regions.* Front Neurosci. 2016;10:81 Authors: Weishaupt N, Zhang A, Deziel RA, Tasker RA, Whitehead SN Abstract Secondary damage processes, such as inflammation and oxidative stress, can exacerbate an ischemic lesion and spread to adjacent brain regions. Yet, few studies investigate how regions remote from the infarct could also suffer from degeneration and inflammation in the aftermath of a stroke. To find out to what extent far-remote brain regions are affected after stroke...περισσότερα »
Inducing Chronic Excitotoxicity in the Mouse Spinal Cord to Investigate Lower Motor Neuron Degeneration.
*Inducing Chronic Excitotoxicity in the Mouse Spinal Cord to Investigate Lower Motor Neuron Degeneration.* Front Neurosci. 2016;10:76 Authors: Blizzard CA, Lee KM, Dickson TC Abstract We report the methodology for the chronic delivery of an excitotoxin to the mouse spinal cord via surgically implanted osmotic mini-pumps. Previous studies have investigated the effect of chronic application of excitotoxins in the rat, however there has been little translation of this model to the mouse. Using mice that express yellow fluorescent protein (YFP), motor neuron and neuromuscular junctio... περισσότερα »
Hypocellularity in the Murine Model for Down Syndrome Ts65Dn Is Not Affected by Adult Neurogenesis.
*Hypocellularity in the Murine Model for Down Syndrome Ts65Dn Is Not Affected by Adult Neurogenesis.* Front Neurosci. 2016;10:75 Authors: López-Hidalgo R, Ballestín R, Vega J, Blasco-Ibáñez JM, Crespo C, Gilabert-Juan J, Nácher J, Varea E Abstract Down syndrome (DS) is caused by the presence of an extra copy of the chromosome 21 and it is the most common aneuploidy producing intellectual disability. Neural mechanisms underlying this alteration may include defects in the formation of neuronal networks, information processing and brain plasticity. The murine model for DS, Ts65Dn, p...περισσότερα »
The Contradictory Effects of Neuronal Hyperexcitation on Adult Hippocampal Neurogenesis.
*The Contradictory Effects of Neuronal Hyperexcitation on Adult Hippocampal Neurogenesis.* Front Neurosci. 2016;10:74 Authors: Pineda JR, Encinas JM Abstract Adult hippocampal neurogenesis is a highly plastic process that responds swiftly to neuronal activity. Adult hippocampal neurogenesis can be regulated at the level of neural stem cell recruitment and activation, progenitor proliferation, as well as newborn cell survival and differentiation. An "excitation-neurogenesis" rule was proposed after the demonstration of the capability of cultured neural stem and progenitor cells t... περισσότερα »
Deficits in the Sensitivity to Pitch Sweeps by School-Aged Children Wearing Cochlear Implants.
*Deficits in the Sensitivity to Pitch Sweeps by School-Aged Children Wearing Cochlear Implants.* Front Neurosci. 2016;10:73 Authors: Deroche ML, Kulkarni AM, Christensen JA, Limb CJ, Chatterjee M Abstract Sensitivity to static changes in pitch has been shown to be poorer in school-aged children wearing cochlear implants (CIs) than children with normal hearing (NH), but it is unclear whether this is also the case for dynamic changes in pitch. Yet, dynamically changing pitch has considerable ecological relevance in terms of natural speech, particularly aspects such as intonation, e...περισσότερα »
Murine Depression Model and its Potential Applications for Discovering Foods and Farm Products with Antidepressant-Like Effects.
*Murine Depression Model and its Potential Applications for Discovering Foods and Farm Products with Antidepressant-Like Effects.* Front Neurosci. 2016;10:72 Authors: Goto T, Tomonaga S, Okayama T, Toyoda A Abstract Advanced societies face increased health problems related to various stresses. Chronic psychological stress is a major risk factor for psychiatric disorders such as depression. Although therapeutic agents reduce several symptoms of depression, most have side effects in a broad range of the population. Furthermore, some victims of depression do not show significant imp...περισσότερα »
BBBomics-Human Blood Brain Barrier Transcriptomics Hub.
*BBBomics-Human Blood Brain Barrier Transcriptomics Hub.* Front Neurosci. 2016;10:71 Authors: Kalari KR, Thompson KJ, Nair AA, Tang X, Bockol MA, Jhawar N, Swaminathan SK, Lowe VJ, Kandimalla KK PMID: 26973449 [PubMed] from #PubMed 3 via ola Kala on Inoreader http://ift.tt/1U3IIQG via IFTTT
Testosterone Administration Related Differences in Brain Activation during the Ultimatum Game.
*Testosterone Administration Related Differences in Brain Activation during the Ultimatum Game.* Front Neurosci. 2016;10:66 Authors: Kopsida E, Berrebi J, Petrovic P, Ingvar M Abstract A plethora of studies on the Ultimatum Game have shown that responders forfeit the rule of profit maximization and punish unfair proposers, by rejecting their offers. This behavior has been linked to increased amygdala, insula, and dorsolateral prefrontal cortex activation. Studies have suggested a potential role of testosterone in the Ultimatum Game albeit with inconsistent findings. In the presen...περισσότερα »
Sexual Stimulation Increases the Survival of New Cells in the Accessory Olfactory Bulb of the Male Rat.
*Sexual Stimulation Increases the Survival of New Cells in the Accessory Olfactory Bulb of the Male Rat.* Front Neurosci. 2016;10:65 Authors: Unda NM, Portillo W, Corona R, Paredes RG Abstract Sexual behavior in rodents is modulated by the olfactory system. The olfactory bulb (OB) is a structure that undergoes continues neurogenesis in adulthood. We have previously shown that 15 days after males rats pace the sexual interaction and ejaculate 1 or 3 times, there is an increase in the density of new cells that reach the accessory olfactory bulb (AOB). The aim of the present study w... περισσότερα »
Hybrid PET/MR Imaging and Brain Connectivity.
*Hybrid PET/MR Imaging and Brain Connectivity.* Front Neurosci. 2016;10:64 Authors: Aiello M, Cavaliere C, Salvatore M Abstract In recent years, brain connectivity is gaining ever-increasing interest from the interdisciplinary research community. The study of brain connectivity is characterized by a multifaceted approach providing both structural and functional evidence of the relationship between cerebral regions at different scales. Although magnetic resonance (MR) is the most established imaging modality for investigating connectivity in vivo, the recent advent of hybrid posit... περισσότερα »
Beta-Band Functional Connectivity is Reorganized in Mild Cognitive Impairment after Combined Computerized Physical and Cognitive Training.
*Beta-Band Functional Connectivity is Reorganized in Mild Cognitive Impairment after Combined Computerized Physical and Cognitive Training.* Front Neurosci. 2016;10:55 Authors: Klados MA, Styliadis C, Frantzidis CA, Paraskevopoulos E, Bamidis PD Abstract Physical and cognitive idleness constitute significant risk factors for the clinical manifestation of age-related neurodegenerative diseases. In contrast, a physically and cognitively active lifestyle may restructure age-declined neuronal networks enhancing neuroplasticity. The present study, investigated the changes of brain's f... περισσότερα »
Direct Imaging of Hippocampal Epileptiform Calcium Motifs Following Kainic Acid Administration in Freely Behaving Mice.
*Direct Imaging of Hippocampal Epileptiform Calcium Motifs Following Kainic Acid Administration in Freely Behaving Mice.* Front Neurosci. 2016;10:53 Authors: Berdyyeva TK, Frady EP, Nassi JJ, Aluisio L, Cherkas Y, Otte S, Wyatt RM, Dugovic C, Ghosh KK, Schnitzer MJ, Lovenberg T, Bonaventure P Abstract Prolonged exposure to abnormally high calcium concentrations is thought to be a core mechanism underlying hippocampal damage in epileptic patients; however, no prior study has characterized calcium activity during seizures in the live, intact hippocampus. We have directly investigate...περισσότερα »
Acquired cholesteatoma epithelial hyperproliferation: Roles of cell proliferation signal pathways
Acquired cholesteatoma epithelial hyperproliferation: Roles of cell proliferation signal pathways: [image: cover.gif?v=1&s=91b5c09aa476055defd12367] Objectives/Hypothesis To review the recent cell proliferation signal pathways in the etiopathogenesis of acquired middle ear cholesteatoma. Data Sources PubMed (to September 2015). Review Methods Articles about cell proliferation signal pathways in the etiopathogenesis of acquired cholesteatoma and treatment advances were searched in the PubMed database, from which 73 were included in this review. Results The exact underlying cellular... περισσότερα »
Performance Monitoring in Medication-Naïve Children with Tourette Syndrome.
*Performance Monitoring in Medication-Naïve Children with Tourette Syndrome.* Front Neurosci. 2016;10:50 Authors: Eichele H, Eichele T, Bjelland I, Høvik MF, Sørensen L, van Wageningen H, Worren MK, Hugdahl K, Plessen KJ Abstract BACKGROUND: Tourette syndrome (TS) is a childhood-onset neurodevelopmental disorder and its impact on cognitive development needs further study. Evidence from neuropsychological, neuroimaging and electrophysiological studies suggests that the decline in tic severity and the ability to suppress tics relate to the development of self-regulatory functions i... περισσότερα »
Automated Spatial Brain Normalization and Hindbrain White Matter Reference Tissue Give Improved [(18)F]-Florbetaben PET Quantitation in Alzheimer's Model Mice.
*Automated Spatial Brain Normalization and Hindbrain White Matter Reference Tissue Give Improved [(18)F]-Florbetaben PET Quantitation in Alzheimer's Model Mice.* Front Neurosci. 2016;10:45 Authors: Overhoff F, Brendel M, Jaworska A, Korzhova V, Delker A, Probst F, Focke C, Gildehaus FJ, Carlsen J, Baumann K, Haass C, Bartenstein P, Herms J, Rominger A Abstract Preclinical PET studies of β-amyloid (Aβ) accumulation are of growing importance, but comparisons between research sites require standardized and optimized methods for quantitation. Therefore, we aimed to evaluate systemat... περισσότερα »
Sociometric status and the attribution of intentions in a sample of adolescents with cerebral palsy.
*Sociometric status and the attribution of intentions in a sample of adolescents with cerebral palsy.* Disabil Rehabil. 2016 Mar 12;:1-6 Authors: Voyer AP, Tessier R, Nadeau L Abstract Purpose To examine how cerebral palsy (CP) and sociometric status at age 10 explain the development of a cognitive bias across two groups of adolescents aged 15. Method Children with CP (N = 60) and without CP (N = 57) are part of a follow-up study. Three categories of sociometric status (popular, average, rejected) were obtained by conducting a class-wide interview in the class of the target child...περισσότερα »
Family caregiving of individuals with traumatic brain injury in Botswana.
*Family caregiving of individuals with traumatic brain injury in Botswana.* Disabil Rehabil. 2016 Mar 13;:1-9 Authors: Mbakile-Mahlanza L, Manderson L, Downing M, Ponsford J Abstract Background The impairments that affect survivors of TBI impact the person's independence, and family members frequently have to take on a caregiver role. This study examined the experience of caregiving for individuals with TBI in Botswana and its impact on psychological distress in caregivers. Methods Using a mixed methods study design, qualitative data from semi-structured interviews were thematical...περισσότερα »
A multidisciplinary learning experience contributing to mental health rehabilitation.
*A multidisciplinary learning experience contributing to mental health rehabilitation.* Disabil Rehabil. 2016 Mar 12;:1-6 Authors: Moxham L, Patterson C, Taylor E, Perlman D, Sumskis S, Brighton R Abstract Purpose People who access health services often have a range of needs that require the involvement of members from a multidisciplinary team. Teaching future health professionals about the importance of a multidisciplinary approach can be challenging. The aim of this paper is to describe a project called Recovery Camp that enhanced multidisciplinary health education through expe... περισσότερα »
Mean platelet volume may not be increased in patients with idiopathic subjective tinnitus.
*Mean platelet volume may not be increased in patients with idiopathic subjective tinnitus.* Eur Arch Otorhinolaryngol. 2016 Mar 14; Authors: Beyan C, Beyan E PMID: 26972569 [PubMed - as supplied by publisher] from Head and Neck on PubMed via xlomafota13 on Inoreader http://ift.tt/1plaxq8 via IFTTT
Silicone Granuloma in the Buttocks Incidentally Detected by 18F-FDG PET/CT 30 Years After Free Liquid Silicone Injections.
*Silicone Granuloma in the Buttocks Incidentally Detected by 18F-FDG PET/CT 30 Years After Free Liquid Silicone Injections.* Clin Nucl Med. 2016 Mar 11; Authors: Ohnona J, Durand P, Amegnizin JL, Kerrou K Abstract A 59-year-old transexual (male to female) patient presented with a squamous cell carcinoma of the larynx. She underwent an F-FDG PET/CT for initial staging. The examination showed high F-FDG uptake of the primary lesion and a homolateral lymphadenopathy. Incidental heterogeneous uptake of round hyperdense lesions in the gluteal muscles and subcutaneous fat was visualize... περισσότερα »
Clinical characteristics of a Japanese family with hearing loss accompanied by compound heterozygous mutations in LOXHD1.
*Clinical characteristics of a Japanese family with hearing loss accompanied by compound heterozygous mutations in LOXHD1.* Auris Nasus Larynx. 2016 Mar 10; Authors: Minami SB, Mutai H, Namba K, Sakamoto H, Matsunaga T Abstract OBJECTIVE: To report two novel LOXHD1 mutations, including missense mutations and the clinical features of the patients. METHODS: We studied a three-generation Japanese family with hearing loss. Targeted next-generation sequencing was used for genetic analysis. Conditional orientation response audiometry and pure tone audiometry were used to assess hearing.... περισσότερα »
Motor function of the recurrent laryngeal nerve: Sometimes motor fibers are also located in the posterior branch.
*Motor function of the recurrent laryngeal nerve: Sometimes motor fibers are also located in the posterior branch.* Surgery. 2016 Mar 10; Authors: Uludag M, Aygun N, Isgor A Abstract BACKGROUND: The function of the extralaryngeal branches of the recurrent laryngeal nerve (RLN) has yet to be described precisely. The goal of this study was to evaluate the incidence and motor function of the extralaryngeal branches of the RLN. METHODS: Our study group consisted of 335 consecutive patients undergoing thyroid and parathyroid operations in whom the branches of the RLNs (n = 200) were e... περισσότερα »
Effect of saline inhalation on vocal fold epithelial morphology evaluated by optical coherence tomography.
*Effect of saline inhalation on vocal fold epithelial morphology evaluated by optical coherence tomography.* Laryngoscope. 2016 Mar 12; Authors: Jungheim M, Donner S, Bleeker S, Ripken T, Krueger A, Ptok M Abstract OBJECTIVES/HYPOTHESIS: Examination of tissue structures by optical coherence tomography (OCT) has been shown to be useful on mucous membranes of the vocal folds, but so far its application to the human larynx has been limited because it is technically cumbersome and usually needs to be performed with sedation. Here a newly developed, noninvasive combined laryngoscopy a... περισσότερα »
Patterns of Recurrence in Electively Irradiated Lymph Node Regions After Definitive Accelerated Intensity Modulated Radiation Therapy for Head and Neck Squamous Cell Carcinoma.
*Patterns of Recurrence in Electively Irradiated Lymph Node Regions After Definitive Accelerated Intensity Modulated Radiation Therapy for Head and Neck Squamous Cell Carcinoma.* Int J Radiat Oncol Biol Phys. 2016 Mar 15;94(4):766-74 Authors: van den Bosch S, Dijkema T, Verhoef LC, Zwijnenburg EM, Janssens GO, Kaanders JH Abstract PURPOSE: To provide a comprehensive risk assessment on the patterns of recurrence in electively irradiated lymph node regions after definitive radiation therapy for head and neck cancer. METHODS AND MATERIALS: Two hundred sixty-four patients with stage ... περισσότερα »
Interactions of subglottal pressure and neuromuscular activation on fundamental frequency and intensity.
*Interactions of subglottal pressure and neuromuscular activation on fundamental frequency and intensity.* Laryngoscope. 2016 Mar 12; Authors: Chhetri DK, Park SJ Abstract OBJECTIVES/HYPOTHESIS: Fundamental frequency (F0) and intensity sound pressure level (SPL) of voice are controlled by intrinsic laryngeal muscle (ILM) activation and subglottal pressure (Psub). Their interactions were investigated. METHODS: In an in vivo canine model, the thyroarytenoid (TA), lateral cricoarytenoid/interarytenoid (LCA/IA), and cricothyroid (CT) muscles were independently activated from threshol...περισσότερα »
Voice features of Parkinson's disease patients with subthalamic nucleus deep brain stimulation.
[image: http:--production.springer.de-OnlineReso] Related Articles *Voice features of Parkinson's disease patients with subthalamic nucleus deep brain stimulation.* J Neurol. 2015 May;262(5):1173-81 Authors: Tanaka Y, Tsuboi T, Watanabe H, Kajita Y, Fujimoto Y, Ohdake R, Yoneyama N, Masuda M, Hara K, Senda J, Ito M, Atsuta N, Horiguchi S, Yamamoto M, Wakabayashi T, Sobue G Abstract Voice and speech disorders are one of the most important issues after subthalamic nucleus deep brain stimulation (STN-DBS) in Parkinson's disease patients; however, their characteristics remain unclear... περισσότερα »
Novel reconstruction of the anterior craniocervical junction using an expandable cage with integrated fixation after total C2 spondylectomy for chordoma.
*Novel reconstruction of the anterior craniocervical junction using an expandable cage with integrated fixation after total C2 spondylectomy for chordoma.* J Clin Neurosci. 2016 Mar 10; Authors: Wewel JT, Nunna RS, Tan LA, Kasliwal MK, O'Toole JE Abstract Chordoma is a locally aggressive malignant tumor that generally occurs in the clivus, mobile spine and sacrum. While en bloc resection with wide margins has been advocated as the only cure for chordomas, tumor characteristics and violation of critical anatomical boundaries may preclude pursuing this treatment option in the cervi... περισσότερα »
Intracerebral hemorrhage with intraventricular extension and no hydrocephalus may not increase mortality or severe disability.
*Intracerebral hemorrhage with intraventricular extension and no hydrocephalus may not increase mortality or severe disability.* J Clin Neurosci. 2016 Mar 10; Authors: Mahta A, Katz PM, Kamel H, Azizi SA Abstract This paper aimed to test the hypothesis that intraventricular extension of spontaneous intracerebral hemorrhage (ICH) in the absence of hydrocephalus is not associated with increased mortality or severe disability. We performed a retrospective consecutive cohort study of patients with primary spontaneous ICH who were admitted to a single institution. Multivariate logisti...περισσότερα »
Leptomeningeal carcinomatosis as primary manifestation of pancreatic cancer.
*Leptomeningeal carcinomatosis as primary manifestation of pancreatic cancer.* J Clin Neurosci. 2016 Mar 10; Authors: Trinh VT, Medina-Flores R, Chohan MO Abstract Leptomeningeal carcinomatosis (LMC) is a rare complication of cancer that often presents at an advanced stage after obvious metastasis of a primary cancer or locally advanced disease. We present an uncommon case of LMC secondary to pancreatic carcinoma presenting with headache, unilateral VII nerve palsy, and lower extremity weakness. Initial cerebrospinal fluid (CSF) studies were concerning for chronic aseptic meningi...περισσότερα »
Midline interhemispheric lesion: answer.
*Midline interhemispheric lesion: answer.* J Clin Neurosci. 2016 Mar;25:170 Authors: O'Donnell K, Gaillard F PMID: 26972675 [PubMed - in process] from Head and Neck on PubMed via xlomafota13 on Inoreader http://ift.tt/1nKYEbV via IFTTT
Thoracic paraspinal lesion: answer.
*Thoracic paraspinal lesion: answer.* J Clin Neurosci. 2016 Mar;25:169 Authors: Kaszuba MC, Kasliwal MK, O'Toole JE PMID: 26972674 [PubMed - in process] from Head and Neck on PubMed via xlomafota13 on Inoreader http://ift.tt/1U3Qvy0 via IFTTT
Midline interhemispheric lesion: question.
*Midline interhemispheric lesion: question.* J Clin Neurosci. 2016 Mar;25:117 Authors: O'Donnell K, Gaillard F PMID: 26972673 [PubMed - in process] from Head and Neck on PubMed via xlomafota13 on Inoreader http://ift.tt/1nKYDVn via IFTTT
Thoracic paraspinal lesion: question.
*Thoracic paraspinal lesion: question.* J Clin Neurosci. 2016 Mar;25:116 Authors: Kaszuba MC, Kasliwal MK, O'Toole JE PMID: 26972672 [PubMed - in process] from Head and Neck on PubMed via xlomafota13 on Inoreader http://ift.tt/1U3QslE via IFTTT
Targeted screening for the detection of Pompe disease in patients with unclassified limb-girdle muscular dystrophy or asymptomatic hyperCKemia using dried blood: A Spanish cohort.
[image: http:--linkinghub.elsevier.com-ihub-imag] Related Articles *Targeted screening for the detection of Pompe disease in patients with unclassified limb-girdle muscular dystrophy or asymptomatic hyperCKemia using dried blood: A Spanish cohort.* Neuromuscul Disord. 2015 Jul;25(7):548-53 Authors: Gutiérrez-Rivas E, Bautista J, Vílchez JJ, Muelas N, Díaz-Manera J, Illa I, Martínez-Arroyo A, Olivé M, Sanz I, Arpa J, Fernández-Torrón R, López de Munáin A, Jiménez L, Solera J, Lukacs Z Abstract We aimed to screen for Pompe disease in patients with unclassified limb-girdle muscular ... περισσότερα »
SIL1-related Marinesco-Sjoegren syndrome (MSS) with associated motor neuronopathy and bradykinetic movement disorder.
[image: http:--linkinghub.elsevier.com-ihub-imag] Related Articles *SIL1-related Marinesco-Sjoegren syndrome (MSS) with associated motor neuronopathy and bradykinetic movement disorder.* Neuromuscul Disord. 2015 Jul;25(7):585-8 Authors: Byrne S, Dlamini N, Lumsden D, Pitt M, Zaharieva I, Muntoni F, King A, Robert L, Jungbluth H Abstract Marinesco-Sjoegren syndrome (MSS) is a recessively inherited multisystem disorder caused by mutations in SIL1 and characterized by cerebellar atrophy with ataxia, cataracts, a skeletal muscle myopathy, and variable degrees of developmental delay. ... περισσότερα »
Clinical characteristics of a Japanese family with hearing loss accompanied by compound heterozygous mutations in LOXHD1.
*Clinical characteristics of a Japanese family with hearing loss accompanied by compound heterozygous mutations in LOXHD1.* Auris Nasus Larynx. 2016 Mar 10; Authors: Minami SB, Mutai H, Namba K, Sakamoto H, Matsunaga T Abstract OBJECTIVE: To report two novel LOXHD1 mutations, including missense mutations and the clinical features of the patients. METHODS: We studied a three-generation Japanese family with hearing loss. Targeted next-generation sequencing was used for genetic analysis. Conditional orientation response audiometry and pure tone audiometry were used to assess hearing.... περισσότερα »
Clinical characteristics of a Japanese family with hearing loss accompanied by compound heterozygous mutations in LOXHD1.
*Clinical characteristics of a Japanese family with hearing loss accompanied by compound heterozygous mutations in LOXHD1.* Auris Nasus Larynx. 2016 Mar 10; Authors: Minami SB, Mutai H, Namba K, Sakamoto H, Matsunaga T Abstract OBJECTIVE: To report two novel LOXHD1 mutations, including missense mutations and the clinical features of the patients. METHODS: We studied a three-generation Japanese family with hearing loss. Targeted next-generation sequencing was used for genetic analysis. Conditional orientation response audiometry and pure tone audiometry were used to assess hearing.... περισσότερα »
Xeroderma Pigmentosum
Abstract Xeroderma pigmentosum (XP) is a rare disorder of defective UV-radiation induced damage repair that is characterized by photosensitivity with easy skin burning following minimal sun exposure, early freckling and development of lentiginous pigmentation along with other features of poikiloderma and a propensity for developing skin cancer at an early age. In this short review, the clinical, pathological, genetic and molecular aspects of XP are reviewed in the current literature. XP encompasses a spectrum of disease that overlaps with other diseases of DNA repair systems. In a... περισσότερα »
Genodermatosis Affecting the Skin and Mucosa of the Head and Neck: Clinicopathologic, Genetic, and Molecular Aspect—PTEN-Hamartoma Tumor Syndrome/Cowden Syndrome
Abstract PTEN hamartoma tumor syndrome refers to a spectrum of disorders caused by mutations in the phosphatase and tensin homolog (*PTEN*) gene. Cowden syndrome, the principal PTEN-related disorder is characterized by multiple neoplasms and hamartomas, mucosal papillomatosis, and skin lesions, trichilemmomas. Trichilemmomas and mucocutaneous papillomatous papules are one of the first signs of the disease. Early recognition of these skin lesions may help on diagnosing an underlying malignancy and early cancer screening. from #ENT via xlomafota13 on Inoreader http://ift.tt/250Fxwt... περισσότερα »
speech and language; +18 new citations
18 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: *speech and language* These pubmed results were generated on 2016/03/15 PubMed comprises more than 24 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites. from #ENT via xlomafota13 on Inoreader http://ift.tt/1QZSIV1 via IFTTT
Interpretation of an Extended Autoantibody Profile in a Well-Characterized Australian Systemic Sclerosis (Scleroderma) Cohort Using Principal Components Analysis.
[image: http:--media.wiley.com-assets-7315-19-Wi] Related Articles *Interpretation of an Extended Autoantibody Profile in a Well-Characterized Australian Systemic Sclerosis (Scleroderma) Cohort Using Principal Components Analysis.* Arthritis Rheumatol. 2015 Dec;67(12):3234-44 Authors: Patterson KA, Roberts-Thomson PJ, Lester S, Tan JA, Hakendorf P, Rischmueller M, Zochling J, Sahhar J, Nash P, Roddy J, Hill C, Nikpour M, Stevens W, Proudman SM, Walker JG Abstract OBJECTIVE: To determine the relationships between systemic sclerosis (SSc)-related autoantibodies, as well as their cl... περισσότερα »
Precision prevention of oesophageal adenocarcinoma.
[image: http:--http://ift.tt/1OOTDZp] [image: http:--http://ift.tt/1Fkw4zC] Related Articles *Precision prevention of oesophageal adenocarcinoma.* Nat Rev Gastroenterol Hepatol. 2015 Apr;12(4):243-8 Authors: Vaughan TL, Fitzgerald RC Abstract The incidence of oesophageal adenocarcinoma has risen rapidly over the past four decades. Unfortunately, treatments have not kept pace; unless their cancer is identified at a very early stage, most patients will not survive a year after diagnosis. The beginnings of this widespread problem were first recognized over 25 years ago, yet rates ha... περισσότερα »
Study design for the fostering eating after stroke with transcranial direct current stimulation trial: a randomized controlled intervention for improving Dysphagia after acute ischemic stroke.
[image: http:--linkinghub.elsevier.com-ihub-imag] [image: http:--http://ift.tt/1Fkw4zC] Related Articles *Study design for the fostering eating after stroke with transcranial direct current stimulation trial: a randomized controlled intervention for improving Dysphagia after acute ischemic stroke.* J Stroke Cerebrovasc Dis. 2015 Mar;24(3):511-20 Authors: Marchina S, Schlaug G, Kumar S Abstract GOAL: Dysphagia is a major stroke complication but lacks effective therapy that can promote recovery. Noninvasive brain stimulation with and without peripheral sensorimotor activities may b... περισσότερα »
Esophagitis due to dexketoprofen trometamol: a rare case report.
[image: http:--production.springer.de-OnlineReso] Related Articles *Esophagitis due to dexketoprofen trometamol: a rare case report.* Wien Klin Wochenschr. 2015 May;127(9-10):399-401 Authors: Olmez S, Donmez S, Aslan M, Karadas S, Yavuz A Abstract Various drugs are known to cause pill esophagitis. Antimicrobial drugs and nonsteroidal anti-inflammatory drugs are the most common causes of pill-induced esophagitis. Most patients suffer only self-limiting pain, but serious complications can occur. A 21-year-old man was admitted to our outpatient clinic with retrosternal chest pain, dy... περισσότερα »
Infected bronchogenic cyst causing dysphagia and retrosternal pain.
[image: http:--media.wiley.com-assets-7315-19-Wi] Related Articles *Infected bronchogenic cyst causing dysphagia and retrosternal pain.* Clin Respir J. 2013 Apr;7(2):e13-4 Authors: Søndergaard EB, Pedersen JH, Kleive D Abstract Bronchogenic cysts are congenital. They are typically discovered in infancy or early childhood. Secondary infection of the cyst is uncommon. We present the case of a 17-year-old female who presented to the emergency department with intermediate onset of upper abdominal, and retrosternal chest pain and fever. Subsequent X-ray and computerised tomography scan... περισσότερα »
Dysphagia and Dysphonia Assessment Tools After Anterior Cervical Spine Surgery.
*Dysphagia and Dysphonia Assessment Tools After Anterior Cervical Spine Surgery.* Clin Spine Surg. 2016 Mar 11; Authors: Rosenthal BD, Nair R, Hsu WK, Patel AA, Savage JW Abstract The Smith-Robinson approach to the anterior cervical spine is being increasingly used, but it is not without complication. Dysphagia and dysphonia are the most common complications of the procedure. Many classification systems have been developed to stage and grade postoperative dysphagia and dysphonia, but inconsistent usage and lack of consensus adoption has limited research progress. A discussion of ... περισσότερα »
The South African dysphagia screening tool (SADS): A screening tool for a developing context.
*The South African dysphagia screening tool (SADS): A screening tool for a developing context.* S Afr J Commun Disord. 2016;63(1):e1-e9 Authors: Ostrofsky C, Seedat J Abstract BACKGROUND: Notwithstanding its value, there are challenges and limitations to implementing a dysphagia screening tool from a developed contexts in a developing context. The need for a reliable and valid screening tool for dysphagia that considers context, systemic rules and resources was identified to prevent further medical compromise, optimise dysphagia prognosis and ultimately hasten patients' return to... περισσότερα »
Implementing oral care to reduce aspiration pneumonia amongst patients with dysphagia in a South African setting.
*Implementing oral care to reduce aspiration pneumonia amongst patients with dysphagia in a South African setting.* S Afr J Commun Disord. 2016;63(1):e1-e11 Authors: Seedat J, Penn C Abstract Oral care is a crucial routine for patients with dysphagia that, when completed routinely, can prevent the development of aspiration pneumonia. There is no standardised protocol for oral care within government hospitals in South Africa. This study aimed to investigate the outcome of an oral care protocol. Participants were patients with oropharyngeal dysphagia, with either stroke or traumati... περισσότερα »
Pulmonary rehabilitation and oral nutritional supplement enriched with beta-hydroxy-beta-methylbutyrate for bronchiectasis participants: A prospective, randomised study.
*Pulmonary rehabilitation and oral nutritional supplement enriched with beta-hydroxy-beta-methylbutyrate for bronchiectasis participants: A prospective, randomised study.* Clin Nutr. 2016 Feb 6; Authors: Kokura Y, Maeda K, Wakabayashi H PMID: 26972090 [PubMed - as supplied by publisher] from #ENT via xlomafota13 on Inoreader http://ift.tt/22i9TZ7 via IFTTT
A cohort study of the morbidity of combined anterior-posterior cervical spinal fusions: incidence and predictors of postoperative dysphagia.
*A cohort study of the morbidity of combined anterior-posterior cervical spinal fusions: incidence and predictors of postoperative dysphagia.* Eur Spine J. 2016 Mar 14; Authors: Reinard KA, Cook DM, Zakaria HM, Basheer AM, Chang VW, Abdulhak MM Abstract PURPOSE: To identify risk factors that may lead to the development of dysphagia after combined anterior and posterior (360°) cervical fusion surgery. METHODS: A single center, retrospective analysis of patients who had same-day, 360° fusion at Henry Ford Hospital between 2008 and 2012 was performed. Variables analyzed included demo... περισσότερα »
Interpretation of an Extended Autoantibody Profile in a Well-Characterized Australian Systemic Sclerosis (Scleroderma) Cohort Using Principal Components Analysis.
[image: http:--media.wiley.com-assets-7315-19-Wi] Related Articles *Interpretation of an Extended Autoantibody Profile in a Well-Characterized Australian Systemic Sclerosis (Scleroderma) Cohort Using Principal Components Analysis.* Arthritis Rheumatol. 2015 Dec;67(12):3234-44 Authors: Patterson KA, Roberts-Thomson PJ, Lester S, Tan JA, Hakendorf P, Rischmueller M, Zochling J, Sahhar J, Nash P, Roddy J, Hill C, Nikpour M, Stevens W, Proudman SM, Walker JG Abstract OBJECTIVE: To determine the relationships between systemic sclerosis (SSc)-related autoantibodies, as well as their cl... περισσότερα »
Tissue Expander Overfilling
Tissue Expander Overfilling: Achieving New Dimensions of Customization in Breast Reconstruction: Introduction: Overfill of tissue expanders is a commonly used modality to achieve customized dimensions in breast reconstruction. Little formal study of the dynamics of hyperexpansion of these devices has been performed to date, however. Methods: Overfill trials were performed using both Natrelle 133 MV and Mentor 8200 tissue expanders of indicated capacities ranging from 250 to 800 mL. Each expander was initially filled to its indicated capacity with normal water and then injected in re... περισσότερα »
Exploring the prevalence of skin tears and skin properties related to skin tears in elderly patients
Exploring the prevalence of skin tears and skin properties related to skin tears in elderly patients at a long-term medical facility in Japan: Abstract The identification of appropriate skin tear prevention guidelines for the elderly requires clinicians to focus on local risk factors such as structural alterations of the epidermis and dermis related to skin tears. The aim of this cross-sectional study is to explore the prevalence of skin tears and to explore skin properties related to skin tears in elderly Japanese patients at a long-term medical facility. After doing the prevalenc... περισσότερα »
Reconstruction after skin cancer excision through a dermal induction template: our experience
Reconstruction after skin cancer excision through a dermal induction template: our experience: Abstract Dermal substitutes offer alternative approaches for wounds of all thicknesses where sufficient donation sites are not available for self-grafts. Several dermal substitutes are described in literature. This study included 20 patients treated with a dermal induction template after the removal of malignant skin cancers situated in various parts of the body. The participants were especially aged patients with multiple skin cancers, and complex clinical conditions, often affected by p... περισσότερα »
Direct intrawound administration of dimethylsulphoxide relieves acute pain
Direct intrawound administration of dimethylsulphoxide relieves acute pain in rats: Abstract Wounds associated with injuries such as burns can produce moderate to severe pain. Besides causing distress to the patient, unrelieved pain could delay healing owing to stress-related problems. Thus, pain needs to be treated as early as possible after injury. It was hypothesised that local treatment of wounds with appropriate analgesic drugs could attenuate pain. HOE 140, a bradykinin receptor antagonist, reduced acute inflammatory pain in rats after intrawound administration. In this study... περισσότερα »
Expression of Epstein–Barr virus in children
Expression of Epstein–Barr virus in children with sacrococcygeal pilonidal sinus determined by immunohistochemical methods: Abstract In this study, we probed whether chronic infections of skin such as pilonidal sinus could be a potential site of Epstein–Barr virus (EBV) replication. Pilonidal sinus is associated with a high recurrence rate. Therefore, we decided to determine the role of EBV's presence to explain whether it is correlated with the recurrence of pilonidal sinuses. This study was conducted on 36 patient samples with sacrococcygeal pilonidal sinus. Samples were immunohi... περισσότερα »
Dynamic biological changes in fibroblasts during hypertrophic scar formation and regression
Dynamic biological changes in fibroblasts during hypertrophic scar formation and regression: Abstract The human hypertrophic scar undergoes hyperplasia and regression during progression. This study aimed to investigate whether fibroblasts in scar tissue undergo biological changes during the formation and regression of human hypertrophic scar. Using 32 scar samples, we measured collagen production by Masson's staining and the expression levels of transforming growth factor (TGF)-β1 and vascular endothelial growth factor (VEGF) by immunohistochemistry. In addition, fibroblasts from s...περισσότερα »
Hyaluronic acid dressing (Healoderm®) in the treatment of diabetic ulcer
Hyaluronic acid dressing (Healoderm®) in the treatment of diabetic foot ulcer: A prospective, randomized, placebo-controlled, single-center study: Abstract Fast and complete healing of a diabetic foot ulcer (DFU) is challenging due to the hostile wound healing environment of the diabetic patients. As a part of a multimodal treatment approach, advanced dressing material using hyaluronic acid (HA) has been found to be effective. However, previous studies have used HA with additional biologics, which interferes in determining the true clinical effect of HA in DFU. To examine the sole ... περισσότερα »
Titanized Polypropylene Mesh and an Anchor System for Correction of Lower Lid Retraction
Usefulness of Titanized Polypropylene Mesh and an Anchor System for Correction of Lower Lid Retraction: [image: image]Summary: Because of the lower eyelid’s free edge anatomy, it is difficult to preserve its contours after reconstruction. We recently attempted a new operative procedure to treat 2 cases of lower lid retraction by using a titanized polypropylene mesh and an anchor system. As the lower lid skin is elevated laterally in an oblique upward direction, the location of the mesh insertion is decided and the site is marked accordingly. The mesh to be inserted is approximately ... περισσότερα »
Congenital Palatal Fistula Associated with Submucous Cleft Palate
Congenital Palatal Fistula Associated with Submucous Cleft Palate: [image: image]Background: Although cleft lip and cleft palate are among the most common congenital malformations, the presence of an isolated congenital palatal fistula along with a submucous cleft is very rare. This appears as an oval-shaped, full-thickness fenestration in the palatal midline that does not fully extend anteriorly or posteriorly, accompanied by the findings of a submucous cleft. Because of the uncommon nature of this entity, there is controversy about its etiology, diagnosis, and management. Metho... περισσότερα »
Idiopathic Orbital Inflammation Associated with Relapsing Polychondritis.
Idiopathic Orbital Inflammation Associated with Relapsing Polychondritis.: The authors describe a patient with recurrent idiopathic orbital inflammatory disease as an unusual presentation of relapsing polychondritis. There are very few reported cases in the literature of relapsing polychondritis associated with idiopathic orbital inflammation. Clinicians should be aware of the orbital and ophthalmic presentations of relapsing polychondritis. (C) 2016 by The American Society of Ophthalmic Plastic and Reconstructive Surgery, Inc., All rights reserved.
Cellulitis OR Cancer
Metastatic Colon Cancer to the Sphenoid Wing and Ethmoid Sinus Mimicking Orbital Cellulitis: A Rare Presentation.: Metastatic lesions to the orbit are most commonly seen with breast, lung, and prostate cancer, but are less commonly seen with colon cancer. Furthermore, the presence of metastatic colon cancer involving the sphenoid wing has only been reported once previously. The authors present a case of a 68-year-old woman with right upper and lower eyelid edema and erythema along with decreased vision, relative afferent pupillary defect, limitation of extraocular movements, and che...περισσότερα »
Metastatic Colon Cancer to the Sphenoid Wing and Ethmoid Sinus Mimicking Orbital Cellulitis
Metastatic Colon Cancer to the Sphenoid Wing and Ethmoid Sinus Mimicking Orbital Cellulitis: A Rare Presentation.: Metastatic lesions to the orbit are most commonly seen with breast, lung, and prostate cancer, but are less commonly seen with colon cancer. Furthermore, the presence of metastatic colon cancer involving the sphenoid wing has only been reported once previously. The authors present a case of a 68-year-old woman with right upper and lower eyelid edema and erythema along with decreased vision, relative afferent pupillary defect, limitation of extraocular movements, and che...περισσότερα »
Primary Periocular Sweat Gland Carcinomas
Epidemiology and Prognosis of Primary Periocular Sweat Gland Carcinomas.: Purpose: To characterize the clinical presentation, management, and outcomes of patients with sweat gland carcinoma of the periocular region. To review the pathologic classification scheme, compare the clinical behavior between subtypes, and discuss treatment recommendations for periocular sweat gland carcinomas. Methods: Retrospective study from 2 tertiary centers, which are part of the American Society of Ophthalmic Plastic and Reconstructive Surgery Oncology Database. Results: Twenty-two patients, of whom ...περισσότερα »
Electrical Nerve Stimulation Enhances Perilesional Branching after Nerve Grafting but Fails to Increase Regeneration Speed
Electrical Nerve Stimulation Enhances Perilesional Branching after Nerve Grafting but Fails to Increase Regeneration Speed in a Murine Model: J reconstr Microsurg DOI: 10.1055/s-0036-1579540 Background Electrical stimulation immediately following nerve lesion helps regenerating axons cross the subsequently grafted nerve repair site. However, the results and the mechanisms remain open to debate. Some findings show that stimulation after crush injury increases axonal crossing of the repair site without affecting regeneration speed. Others show that stimulation after transection and f... περισσότερα »
Maxillofacial morphologies, bone properties, and bone metabolic markers in patients with jaw deformities
Relationships among via Oral and Maxillofacial Surgery Publication date: Available online 11 March 2016 *Source:*International Journal of Oral and Maxillofacial Surgery Author(s): D. Saito, T. Mikami, Y. Oda, D. Hasebe, H. Nishiyama, I. Saito, T. Kobayashi The aim of this study was to determine the relationships among bone properties, bone metabolic markers, and types of jaw deformity. The subjects were 55 female patients with jaw deformities. Skeletal morphology was examined using lateral cephalograms, and the patients were divided into three groups according to the type of anteropos... περισσότερα »
Asymptomatic retinal arteriole emboli and calcified carotid plaque
Meaningful correlation between asymptomatic retinal arteriole emboli and calcified carotid plaque found on panoramic dental imaging of males with diabetes via Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology Publication date: April 2016 *Source:*Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology, Volume 121, Issue 4 Author(s): Arthur H. Friedlander, JoAnn A. Giaconi, Irena Tsui, Nona Aghazadehsanai, Tina I. Chang, Neal R. Garrett ObjectiveThere is ongoing controversy with regard to the stability of calcified carotid artery plaques (CCAPs) seen in the bifurcati... περισσότερα »
Mandibular gingival ulcers : Posttransplant lymphoproliferative disorders (PTLDs)
Epstein-Barr virus (EBV)–associated posttransplant lymphoproliferative disorder appearing as mandibular gingival ulcers via Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology Publication date: April 2016 *Source:*Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology, Volume 121, Issue 4 Author(s): Ana Carolina Amorim Pellicioli, Aline Alves Luciano, Ana Lúcia Carrinho Ayroza Rangel, Greison Rabelo de Oliveira, Alan Roger Santos Silva, Oslei Paes de Almeida, Pablo Agustin Vargas Posttransplant lymphoproliferative disorders (PTLDs) comprise a spectrum of complicati...περισσότερα »
Le lymphome T/NK de type nasal
Lymphome T/NK de type nasal : une pathologie rare de mauvais pronostic via Revue de Stomatologie, de Chirurgie Maxillo-faciale et de Chirurgie Orale Publication date: Available online 10 March 2016 *Source:*Revue de Stomatologie, de Chirurgie Maxillo-faciale et de Chirurgie Orale Author(s): K. Doh, E. Tagba, I. Thiam, A. Sarr, G. Woto-Gaye IntroductionLe lymphome T/NK de type nasal a été décrit en 1933 comme un granulome malin médio-facial. Le diagnostic de cette affection rare est clinique et immunohistopathologique. Nous rapportons un cas de lymphome T/NK diagnostiqué à un stade tard...περισσότερα »
Dental extractions after radiotherapy for HNC : Prophylactic use of pentoxifylline and tocopherol
Prophylactic use of pentoxifylline and tocopherol in patients who require dental extractions after radiotherapy for cancer of the head and neck via British Journal of Oral and Maxillofacial Surgery Publication date: Available online 11 March 2016 *Source:*British Journal of Oral and Maxillofacial Surgery Author(s): Vinod Patel, Yusuf Gadiwalla, Isabel Sassoon, Chris Sproat, Jerry Kwok, Mark McGurk Osteoradionecrosis (ORN) is a complication seen intermittently in patients who have had radiotherapy to the head and neck, and results of treatment with pentoxifylline and tocopherol (PVe) hav... περισσότερα »
Telephone review after minor oral surgery
Telephone review after minor oral surgery via British Journal of Oral and Maxillofacial Surgery *Source:*British Journal of Oral and Maxillofacial Surgery Author(s): J.P. Wells, Z. Roked, S.C. Moore, V. Sivarajasingam An audit of outpatient clinic attendances at Cardiff Dental Hospital (between September 2009 and March 2010) showed that 30% of patients failed to attend review appointments after minor operations. To reduce rates of non-attendance we set up a system of telephone review in March 2010. Patients were given a telephone appointment two weeks after their minor operation (mainl...περισσότερα »
Bleeding after tooth extraction in patients taking aspirin (ASA) 80mg and clopidogrel (Plavix®) 75mg
compared with healthy controls via British Journal of Oral and Maxillofacial Surgery *Source:*British Journal of Oral and Maxillofacial Surgery Author(s): Mohsen Sadeghi-Ghahrody, Seyed Hamid Yousefi-Malekshah, Hamidreza Karimi-Sari, Hamid Yazdanpanah, Mohammad Saeid Rezaee-Zavareh, Mohammadhosein Yavarahmadi The risk of perioperative bleeding is high in patients who take aspirin and clopidogrel after a percutaneous coronary intervention, and whether to stop the drugs is a matter of concern for dentists. The aim of this study was to answer the specific question: should aspirin and cl...περισσότερα »
Staged extubation to manage the airway after operations on the head and neck
Staged extubation to manage the airway after operations on the head and neck via British Journal of Oral and Maxillofacial Surgery *Source:*British Journal of Oral and Maxillofacial Surgery Author(s): Eoin M. Twohig, Ross Leader, Richard J. Shaw, Peter Charters Management of the airway after operations on the head and neck is potentially problematic. We describe leaving a guidewire in the trachea after successful extubation in two patients, to make reintubation easier if the airway was later compromised.
Transoral removal of a distal salivary stone without sialodochoplasty
Anatomical study of the submandibular gland duct after removal of a distal stone without sialodochoplasty: a sialographic evaluation of a clinical phase II trial via British Journal of Oral and Maxillofacial Surgery *Source:*British Journal of Oral and Maxillofacial Surgery Author(s): Seung Hoon Woo, Min Su Kwon, Jung Je Park, Jin Pyeong Kim Transoral removal of a distal salivary stone is common. We have used postoperative sialography to evaluate the results and changes in the salivary ducts after removal of a salivary distal stone without sialodochoplasty. Of 20 patients who had had t... περισσότερα »
Alendronate-related osteonecrosis of the jaw
Epidemiological study of alendronate-related osteonecrosis of the jaw in the southeast of Scotland via British Journal of Oral and Maxillofacial Surgery *Source:*British Journal of Oral and Maxillofacial Surgery Author(s): Stephanie Sammut, Nick Malden, Victor Lopes, Stuart Ralston We aimed to establish the incidence of alendronate-related osteonecrosis of the jaw (ONJ) in the southeast of Scotland, and to assess the effect of corticosteroids on it. We studied a prospective case series of patients between June 2004 and March 2012 separated into steroid and non-steroid groups. There wer... περισσότερα »
Xeroderma Pigmentosum
Abstract Xeroderma pigmentosum (XP) is a rare disorder of defective UV-radiation induced damage repair that is characterized by photosensitivity with easy skin burning following minimal sun exposure, early freckling and development of lentiginous pigmentation along with other features of poikiloderma and a propensity for developing skin cancer at an early age. In this short review, the clinical, pathological, genetic and molecular aspects of XP are reviewed in the current literature. XP encompasses a spectrum of disease that overlaps with other diseases of DNA repair systems. In a... περισσότερα »
Genodermatosis Affecting the Skin and Mucosa of the Head and Neck: Clinicopathologic, Genetic, and Molecular Aspect—PTEN-Hamartoma Tumor Syndrome/Cowden Syndrome
Abstract PTEN hamartoma tumor syndrome refers to a spectrum of disorders caused by mutations in the phosphatase and tensin homolog (*PTEN*) gene. Cowden syndrome, the principal PTEN-related disorder is characterized by multiple neoplasms and hamartomas, mucosal papillomatosis, and skin lesions, trichilemmomas. Trichilemmomas and mucocutaneous papillomatous papules are one of the first signs of the disease. Early recognition of these skin lesions may help on diagnosing an underlying malignancy and early cancer screening. from #ENT via xlomafota13 on Inoreader http://ift.tt/250Fxwt... περισσότερα »
speech and language; +18 new citations
18 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: *speech and language* These pubmed results were generated on 2016/03/15 PubMed comprises more than 24 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites. from #ENT via xlomafota13 on Inoreader http://ift.tt/1QZSIV1 via IFTTT
Interpretation of an Extended Autoantibody Profile in a Well-Characterized Australian Systemic Sclerosis (Scleroderma) Cohort Using Principal Components Analysis.
[image: http:--media.wiley.com-assets-7315-19-Wi] Related Articles *Interpretation of an Extended Autoantibody Profile in a Well-Characterized Australian Systemic Sclerosis (Scleroderma) Cohort Using Principal Components Analysis.* Arthritis Rheumatol. 2015 Dec;67(12):3234-44 Authors: Patterson KA, Roberts-Thomson PJ, Lester S, Tan JA, Hakendorf P, Rischmueller M, Zochling J, Sahhar J, Nash P, Roddy J, Hill C, Nikpour M, Stevens W, Proudman SM, Walker JG Abstract OBJECTIVE: To determine the relationships between systemic sclerosis (SSc)-related autoantibodies, as well as their cl... περισσότερα »
Precision prevention of oesophageal adenocarcinoma.
[image: http:--http://ift.tt/1OOTDZp] [image: http:--http://ift.tt/1Fkw4zC] Related Articles *Precision prevention of oesophageal adenocarcinoma.* Nat Rev Gastroenterol Hepatol. 2015 Apr;12(4):243-8 Authors: Vaughan TL, Fitzgerald RC Abstract The incidence of oesophageal adenocarcinoma has risen rapidly over the past four decades. Unfortunately, treatments have not kept pace; unless their cancer is identified at a very early stage, most patients will not survive a year after diagnosis. The beginnings of this widespread problem were first recognized over 25 years ago, yet rates ha... περισσότερα »
Study design for the fostering eating after stroke with transcranial direct current stimulation trial: a randomized controlled intervention for improving Dysphagia after acute ischemic stroke.
[image: http:--linkinghub.elsevier.com-ihub-imag] [image: http:--http://ift.tt/1Fkw4zC] Related Articles *Study design for the fostering eating after stroke with transcranial direct current stimulation trial: a randomized controlled intervention for improving Dysphagia after acute ischemic stroke.* J Stroke Cerebrovasc Dis. 2015 Mar;24(3):511-20 Authors: Marchina S, Schlaug G, Kumar S Abstract GOAL: Dysphagia is a major stroke complication but lacks effective therapy that can promote recovery. Noninvasive brain stimulation with and without peripheral sensorimotor activities may b... περισσότερα »
Esophagitis due to dexketoprofen trometamol: a rare case report.
[image: http:--production.springer.de-OnlineReso] Related Articles *Esophagitis due to dexketoprofen trometamol: a rare case report.* Wien Klin Wochenschr. 2015 May;127(9-10):399-401 Authors: Olmez S, Donmez S, Aslan M, Karadas S, Yavuz A Abstract Various drugs are known to cause pill esophagitis. Antimicrobial drugs and nonsteroidal anti-inflammatory drugs are the most common causes of pill-induced esophagitis. Most patients suffer only self-limiting pain, but serious complications can occur. A 21-year-old man was admitted to our outpatient clinic with retrosternal chest pain, dy... περισσότερα »
Infected bronchogenic cyst causing dysphagia and retrosternal pain.
[image: http:--media.wiley.com-assets-7315-19-Wi] Related Articles *Infected bronchogenic cyst causing dysphagia and retrosternal pain.* Clin Respir J. 2013 Apr;7(2):e13-4 Authors: Søndergaard EB, Pedersen JH, Kleive D Abstract Bronchogenic cysts are congenital. They are typically discovered in infancy or early childhood. Secondary infection of the cyst is uncommon. We present the case of a 17-year-old female who presented to the emergency department with intermediate onset of upper abdominal, and retrosternal chest pain and fever. Subsequent X-ray and computerised tomography scan... περισσότερα »
Dysphagia and Dysphonia Assessment Tools After Anterior Cervical Spine Surgery.
*Dysphagia and Dysphonia Assessment Tools After Anterior Cervical Spine Surgery.* Clin Spine Surg. 2016 Mar 11; Authors: Rosenthal BD, Nair R, Hsu WK, Patel AA, Savage JW Abstract The Smith-Robinson approach to the anterior cervical spine is being increasingly used, but it is not without complication. Dysphagia and dysphonia are the most common complications of the procedure. Many classification systems have been developed to stage and grade postoperative dysphagia and dysphonia, but inconsistent usage and lack of consensus adoption has limited research progress. A discussion of ... περισσότερα »
The South African dysphagia screening tool (SADS): A screening tool for a developing context.
*The South African dysphagia screening tool (SADS): A screening tool for a developing context.* S Afr J Commun Disord. 2016;63(1):e1-e9 Authors: Ostrofsky C, Seedat J Abstract BACKGROUND: Notwithstanding its value, there are challenges and limitations to implementing a dysphagia screening tool from a developed contexts in a developing context. The need for a reliable and valid screening tool for dysphagia that considers context, systemic rules and resources was identified to prevent further medical compromise, optimise dysphagia prognosis and ultimately hasten patients' return to... περισσότερα »
Implementing oral care to reduce aspiration pneumonia amongst patients with dysphagia in a South African setting.
*Implementing oral care to reduce aspiration pneumonia amongst patients with dysphagia in a South African setting.* S Afr J Commun Disord. 2016;63(1):e1-e11 Authors: Seedat J, Penn C Abstract Oral care is a crucial routine for patients with dysphagia that, when completed routinely, can prevent the development of aspiration pneumonia. There is no standardised protocol for oral care within government hospitals in South Africa. This study aimed to investigate the outcome of an oral care protocol. Participants were patients with oropharyngeal dysphagia, with either stroke or traumati... περισσότερα »
Pulmonary rehabilitation and oral nutritional supplement enriched with beta-hydroxy-beta-methylbutyrate for bronchiectasis participants: A prospective, randomised study.
*Pulmonary rehabilitation and oral nutritional supplement enriched with beta-hydroxy-beta-methylbutyrate for bronchiectasis participants: A prospective, randomised study.* Clin Nutr. 2016 Feb 6; Authors: Kokura Y, Maeda K, Wakabayashi H PMID: 26972090 [PubMed - as supplied by publisher] from #ENT via xlomafota13 on Inoreader http://ift.tt/22i9TZ7 via IFTTT
A cohort study of the morbidity of combined anterior-posterior cervical spinal fusions: incidence and predictors of postoperative dysphagia.
*A cohort study of the morbidity of combined anterior-posterior cervical spinal fusions: incidence and predictors of postoperative dysphagia.* Eur Spine J. 2016 Mar 14; Authors: Reinard KA, Cook DM, Zakaria HM, Basheer AM, Chang VW, Abdulhak MM Abstract PURPOSE: To identify risk factors that may lead to the development of dysphagia after combined anterior and posterior (360°) cervical fusion surgery. METHODS: A single center, retrospective analysis of patients who had same-day, 360° fusion at Henry Ford Hospital between 2008 and 2012 was performed. Variables analyzed included demo... περισσότερα »
Evaluation of mandibular contour in patients with significant facial asymmetry
Evaluation of mandibular contour in patients with significant facial asymmetry via Oral and Maxillofacial Surgery *Source:*International Journal of Oral and Maxillofacial Surgery Author(s): J.-J. Fang, Y.-H. Tu, T.-Y. Wong, J.-K. Liu, Y.-X. Zhang, I.-F. Leong, K.-C. Chen Most previous studies on facial asymmetry have not specifically differentiated mandible deviation from structural asymmetry of the mandible. The purpose of this study was to assess the symmetry of the mandible by examining its contour in a cohort of patients with significant facial asymmetry. Eleven cases of facial as... περισσότερα »
Recurrent G12V pathogenic mutation in adenomatoid odontogenic tumours
Recurrent G12V pathogenic mutation in adenomatoid odontogenic tumours: The adenomatoid odontogenic tumour (AOT) is a non-aggressive encapsulated tumour, being usually diagnosed in association with an unerupted permanent maxillary canine [1,2]. There are scarce reports of multiple AOTs [3–5] and a patient with Schimmelpenning syndrome (SS) with AOT was reported [6]. SS is characterized by sebaceous nevi, associated with ipsilateral abnormalities of the central nervous system, resulting from postzygotic autosomal dominant HRAS or KRAS lethal mutations that survive by somatic mosaicism... περισσότερα »
Improvement of the lower facial contour using a three-dimensional, custom-made, positional stent
New technique to improve lower facial contour using a three-dimensional, custom-made, positional stent via British Journal of Oral and Maxillofacial Surgery Figures and tables 1. [image: Stereolithographic model showing the planned osteotomy cuts.] 2. [image: Silicone surgical template secured to the osseous mandible and chin complex with ...] 3. [image: Measured amount of bone removed after osteotomy.] *Source:*British Journal of Oral and Maxillofacial Surgery Author(s): Natasha Berridge, Manolis Heliotis
Level II neck dissection : Internal Jugular Vein Duplication: Anatomic Relationship With The Spinal Accessory Nerve
Internal Jugular Vein Duplication: Anatomic Relationship With The Spinal Accessory Nerve via Oral and Maxillofacial Surgery Publication date: Available online 12 March 2016 *Source:*Journal of Oral and Maxillofacial Surgery Author(s): Badr Ibrahim, Ilyes Berania, Sami P. Moubayed, Apostolos Christopoulos, Tareck Ayad Level II neck dissection is a commonly performed procedure in head and neck surgery. It carries the risk of injury to the spinal accessory nerve (SAN) and the internal jugular vein (IJV). Injury to any of these structures leads to increased intraoperative and post-operativ... περισσότερα »
Hepatic decompensation/serious adverse events in post-liver transplantation recipients on sofosbuvir for recurrent hepatitis C virus
AlexAndros SfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026Πριν από 20 δευτερόλεπτα
World Journal of Gastroenterology from Gastroenterology via xlomafota13 on Inoreader http://ift.tt/1WmR7fz via IFTTT
Colorectal cancer screening rates increased after exposure to the patient-centered medical home (pcmh)
AlexAndros SfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026Πριν από 20 δευτερόλεπτα
Journal of the American Board of Family Medicine from Gastroenterology via xlomafota13 on Inoreader http://ift.tt/1TKD7yp via IFTTT
Efficacy and safety study of cenicriviroc for the treatment of non-alcoholic steatohepatitis in adult subjects with liver fibrosis: CENTAUR phase 2b study design
AlexAndros SfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026Πριν από 20 δευτερόλεπτα
Contemporary Clinical Trials from Gastroenterology via xlomafota13 on Inoreader http://ift.tt/1WmR6Z8 via IFTTT
HCV false positive immunoassays in patients with LVAD: A potential trap
AlexAndros SfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026Πριν από 20 δευτερόλεπτα
Journal of Clinical Virology from Gastroenterology via xlomafota13 on Inoreader http://ift.tt/1TKD1Xz via IFTTT
Increased risk of colorectal neoplasia in patients with primary sclerosing cholangitis and inflammatory bowel disease: a meta-analysis of 16 observational studies
AlexAndros SfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026Πριν από 20 δευτερόλεπτα
European Journal of Gastroenterology & Hepatology from Gastroenterology via xlomafota13 on Inoreader http://ift.tt/1WmR5nV via IFTTT
Development of a simple, peripheral blood-based lateral-flow dipstick assay for accurate detection of patients with enteric fever
AlexAndros SfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026Πριν από 20 δευτερόλεπτα
Clinical and Vaccine Immunology from Gastroenterology via xlomafota13 on Inoreader http://ift.tt/1TKD4T1 via IFTTT
Effect of Helicobacter pylori infection and its eradication on the fate of gastric polyps
AlexAndros SfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026Πριν από 20 δευτερόλεπτα
European Journal of Gastroenterology & Hepatology from Gastroenterology via xlomafota13 on Inoreader http://ift.tt/1WmR57s via IFTTT
Comparative genomic analysis of toxin-negative strains of Clostridium difficile from humans and animals with symptoms of gastrointestinal disease
AlexAndros SfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026Πριν από 20 δευτερόλεπτα
BMC Microbiology from Gastroenterology via xlomafota13 on Inoreader http://ift.tt/1TKD4CB via IFTTT
HLA-A is a predictor of hepatitis B e antigen status in HIV-positive African adults
AlexAndros SfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026Πριν από 20 δευτερόλεπτα
The Journal of Infectious Diseases from Gastroenterology via xlomafota13 on Inoreader http://ift.tt/1WmR6Im via IFTTT
Association between psoriasis and inflammatory bowel disease - a Danish nationwide cohort study
AlexAndros SfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026Πριν από 20 δευτερόλεπτα
British Journal of Dermatology from Gastroenterology via xlomafota13 on Inoreader http://ift.tt/1TKD1qq via IFTTT
Association of work productivity with clinical and patient-reported factors in patients infected with hepatitis C virus
AlexAndros SfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026Πριν από 20 δευτερόλεπτα
Journal of Viral Hepatitis from Gastroenterology via xlomafota13 on Inoreader http://ift.tt/1WmR3wr via IFTTT
Surgical resection of hepatic metastases from gastric cancer: outcomes from national series in England
AlexAndros SfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026Πριν από 20 δευτερόλεπτα
Gastric Cancer from Gastroenterology via xlomafota13 on Inoreader http://ift.tt/1TKD1a0 via IFTTT
Influence of female sex on hepatitis C virus infection progression and treatment outcomes
AlexAndros SfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026Πριν από 20 δευτερόλεπτα
European Journal of Gastroenterology & Hepatology from Gastroenterology via xlomafota13 on Inoreader http://ift.tt/1WmR4QN via IFTTT
Nonalcoholic fatty liver is not associated with incident chronic kidney disease: a large histology-based comparison with healthy individuals
AlexAndros SfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026Πριν από 20 δευτερόλεπτα
European Journal of Gastroenterology & Hepatology from Gastroenterology via xlomafota13 on Inoreader http://ift.tt/1TKD19N via IFTTT
Efficacy and safety of sofosbuvir/ledipasvir for the treatment of patients with hepatitis C virus re-infection after liver transplantation
AlexAndros SfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026Πριν από 20 δευτερόλεπτα
Transplant Infectious Disease from Gastroenterology via xlomafota13 on Inoreader http://ift.tt/1WmR4Ai via IFTTT
Hypersplenism in liver disease and SLE revisited: current evidence supports an active rather than passive process
AlexAndros SfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026Πριν από 20 δευτερόλεπτα
BMC Hematology from Gastroenterology via xlomafota13 on Inoreader http://ift.tt/1TKD3yH via IFTTT
Genomic Selection in Multi-environment Crop Trials
AlexAndros SfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026Πριν από 20 δευτερόλεπτα
Genomic selection in crop breeding introduces modelling challenges not found in animal studies. These include the need to accommodate replicate plants for each line, consider spatial variation in field trials, address line by environment interactions, and capture non-additive effects. Here we propose a flexible single-stage genomic selection approach that resolves these issues. Our linear mixed model incorporates spatial variation through environment-specific terms and also randomisation-based design terms. It considers marker and marker by environment interactions using ridge reg... περισσότερα »
Lipopolysaccharide structure and biosynthesis in Helicobacter pylori
AlexAndros SfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026Πριν από 20 δευτερόλεπτα
Helicobacter from Gastroenterology via xlomafota13 on Inoreader http://ift.tt/1WmR4jJ via IFTTT
Multiple Targets on the Gln3 Transcription Activator Are Cumulatively Required for Control of Its Cytoplasmic Sequestration
AlexAndros SfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026Πριν από 20 δευτερόλεπτα
A remarkable characteristic of nutritional homeostatic mechanisms is the breadth of metabolite concentrations to which they respond and resolution of those responses; adequate but rarely excessive. Two general ways of achieving such exquisite control are known: stoichiometric mechanisms where increasing metabolite concen-trations elicit proportionally increasing responses, and the actions of multiple independent metabolic signals that cumulatively generate appropriately measured responses. Intracellular localization of the nitrogen-responsive transcription activator, Gln3 responds...περισσότερα »
The HIST1 Locus Escapes Reprogramming in Cloned Bovine Embryos
AlexAndros SfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026Πριν από 20 δευτερόλεπτα
Epigenetic reprogramming is necessary in somatic cell nuclear transfer (SCNT) embryos in order to erase the differentiation-associated epigenetic marks of donor cells. However, such epigenetic memories often persist throughout the course of clonal development, thus decreasing the cloning efficiency. Here, we explored reprogramming-refractory regions in bovine SCNT blastocyst transcriptomes. We observed that histone genes residing in the 1.5 Mb-spanning cow *HIST1* cluster were coordinately downregulated in SCNT blastocysts. In contrast, both the non-histone genes of this cluster, ...περισσότερα »
The peripheral–central chemoreflex interaction: where do we stand and what is the next step?
AlexAndros SfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026Πριν από 20 δευτερόλεπτα
from Physiology via xlomafota13 on Inoreader http://ift.tt/1WmCGbj via IFTTT
Preparing for Winter: the Transcriptomic Response Associated with Different Day Lengths in Drosophila montana
AlexAndros SfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026Πριν από 20 δευτερόλεπτα
At northern latitudes the most robust cue for assessing the onset of winter is the shortening of day lengths, and many species use day length as a cue to increase their cold tolerance and/or enter into diapause but little is known about changes in gene expression that occur under different day lengths. We investigate the gene expression changes associated with differences in light/dark cycles in *Drosophila montana*, a northerly distributed species with a strong adult photoperiodic reproductive diapause. To examine gene expression changes induced by light both prior to, and during...περισσότερα »
Channelling frozen cells to survival after thawing: opening the door to cryo-physiology
AlexAndros SfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026Πριν από 20 δευτερόλεπτα
from Physiology via xlomafota13 on Inoreader http://ift.tt/1U3cKnO via IFTTT
The Arabidopsis Auxin Receptor F-box proteins AFB4 and AFB5 are Required for Response to the Synthetic Auxin Picloram
AlexAndros SfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026Πριν από 20 δευτερόλεπτα
The plant hormone auxin is perceived by a family of F-box proteins called the TIR1/AFBs. Phylogenetic studies reveal that these proteins fall into four clades in flowering plants called TIR1, AFB2, AFB4, and AFB6 (Parry *et al.* 2009). Genetic studies indicate that members of the TIR1 and AFB2 groups act as positive regulators of auxin signaling by promoting the degradation of the Aux/IAA transcriptional repressors (Dharmasiri *et al.* 2005; Parry *et al.* 2009). In this report, we demonstrate that both AFB4 and AFB5 also function as auxin receptors based on *in vitro* assays. We ... περισσότερα »
CO2 – friend or foe?
AlexAndros SfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026Πριν από 20 δευτερόλεπτα
from Physiology via xlomafota13 on Inoreader http://ift.tt/1WmCF7i via IFTTT
The solution to frequent injections
Alexandros G. SfakianakisστοOnline Medical Journals by Alexandros G.SfakianakisΠριν από 22 δευτερόλεπτα
Interpretation of an Extended Autoantibody Profile in a Well-Characterized Australian Systemic Sclerosis (Scleroderma) Cohort Using Principal Components Analysis.
[image: http:--media.wiley.com-assets-7315-19-Wi] Related Articles *Interpretation of an Extended Autoantibody Profile in a Well-Characterized Australian Systemic Sclerosis (Scleroderma) Cohort Using Principal Components Analysis.* Arthritis Rheumatol. 2015 Dec;67(12):3234-44 Authors: Patterson KA, Roberts-Thomson PJ, Lester S, Tan JA, Hakendorf P, Rischmueller M, Zochling J, Sahhar J, Nash P, Roddy J, Hill C, Nikpour M, Stevens W, Proudman SM, Walker JG Abstract OBJECTIVE: To determine the relationships between systemic sclerosis (SSc)-related autoantibodies, as well as their cli... περισσότερα »
Precision prevention of oesophageal adenocarcinoma.
[image: http:--http://ift.tt/1OOTDZp] [image: http:--http://ift.tt/1Fkw4zC] Related Articles *Precision prevention of oesophageal adenocarcinoma.* Nat Rev Gastroenterol Hepatol. 2015 Apr;12(4):243-8 Authors: Vaughan TL, Fitzgerald RC Abstract The incidence of oesophageal adenocarcinoma has risen rapidly over the past four decades. Unfortunately, treatments have not kept pace; unless their cancer is identified at a very early stage, most patients will not survive a year after diagnosis. The beginnings of this widespread problem were first recognized over 25 years ago, yet rates hav... περισσότερα »
Study design for the fostering eating after stroke with transcranial direct current stimulation trial: a randomized controlled intervention for improving Dysphagia after acute ischemic stroke.
[image: http:--linkinghub.elsevier.com-ihub-imag] [image: http:--http://ift.tt/1Fkw4zC] Related Articles *Study design for the fostering eating after stroke with transcranial direct current stimulation trial: a randomized controlled intervention for improving Dysphagia after acute ischemic stroke.* J Stroke Cerebrovasc Dis. 2015 Mar;24(3):511-20 Authors: Marchina S, Schlaug G, Kumar S Abstract GOAL: Dysphagia is a major stroke complication but lacks effective therapy that can promote recovery. Noninvasive brain stimulation with and without peripheral sensorimotor activities may be... περισσότερα »
Esophagitis due to dexketoprofen trometamol: a rare case report.
[image: http:--production.springer.de-OnlineReso] Related Articles *Esophagitis due to dexketoprofen trometamol: a rare case report.* Wien Klin Wochenschr. 2015 May;127(9-10):399-401 Authors: Olmez S, Donmez S, Aslan M, Karadas S, Yavuz A Abstract Various drugs are known to cause pill esophagitis. Antimicrobial drugs and nonsteroidal anti-inflammatory drugs are the most common causes of pill-induced esophagitis. Most patients suffer only self-limiting pain, but serious complications can occur. A 21-year-old man was admitted to our outpatient clinic with retrosternal chest pain, dys... περισσότερα »
Infected bronchogenic cyst causing dysphagia and retrosternal pain.
[image: http:--media.wiley.com-assets-7315-19-Wi] Related Articles *Infected bronchogenic cyst causing dysphagia and retrosternal pain.* Clin Respir J. 2013 Apr;7(2):e13-4 Authors: Søndergaard EB, Pedersen JH, Kleive D Abstract Bronchogenic cysts are congenital. They are typically discovered in infancy or early childhood. Secondary infection of the cyst is uncommon. We present the case of a 17-year-old female who presented to the emergency department with intermediate onset of upper abdominal, and retrosternal chest pain and fever. Subsequent X-ray and computerised tomography scan ... περισσότερα »
Interpretation of an Extended Autoantibody Profile in a Well-Characterized Australian Systemic Sclerosis (Scleroderma) Cohort Using Principal Components Analysis.
[image: http:--media.wiley.com-assets-7315-19-Wi] Related Articles *Interpretation of an Extended Autoantibody Profile in a Well-Characterized Australian Systemic Sclerosis (Scleroderma) Cohort Using Principal Components Analysis.* Arthritis Rheumatol. 2015 Dec;67(12):3234-44 Authors: Patterson KA, Roberts-Thomson PJ, Lester S, Tan JA, Hakendorf P, Rischmueller M, Zochling J, Sahhar J, Nash P, Roddy J, Hill C, Nikpour M, Stevens W, Proudman SM, Walker JG Abstract OBJECTIVE: To determine the relationships between systemic sclerosis (SSc)-related autoantibodies, as well as their cli... περισσότερα »
Precision prevention of oesophageal adenocarcinoma.
[image: http:--http://ift.tt/1OOTDZp] [image: http:--http://ift.tt/1Fkw4zC] Related Articles *Precision prevention of oesophageal adenocarcinoma.* Nat Rev Gastroenterol Hepatol. 2015 Apr;12(4):243-8 Authors: Vaughan TL, Fitzgerald RC Abstract The incidence of oesophageal adenocarcinoma has risen rapidly over the past four decades. Unfortunately, treatments have not kept pace; unless their cancer is identified at a very early stage, most patients will not survive a year after diagnosis. The beginnings of this widespread problem were first recognized over 25 years ago, yet rates hav... περισσότερα »
Study design for the fostering eating after stroke with transcranial direct current stimulation trial: a randomized controlled intervention for improving Dysphagia after acute ischemic stroke.
[image: http:--linkinghub.elsevier.com-ihub-imag] [image: http:--http://ift.tt/1Fkw4zC] Related Articles *Study design for the fostering eating after stroke with transcranial direct current stimulation trial: a randomized controlled intervention for improving Dysphagia after acute ischemic stroke.* J Stroke Cerebrovasc Dis. 2015 Mar;24(3):511-20 Authors: Marchina S, Schlaug G, Kumar S Abstract GOAL: Dysphagia is a major stroke complication but lacks effective therapy that can promote recovery. Noninvasive brain stimulation with and without peripheral sensorimotor activities may be... περισσότερα »
Esophagitis due to dexketoprofen trometamol: a rare case report.
[image: http:--production.springer.de-OnlineReso] Related Articles *Esophagitis due to dexketoprofen trometamol: a rare case report.* Wien Klin Wochenschr. 2015 May;127(9-10):399-401 Authors: Olmez S, Donmez S, Aslan M, Karadas S, Yavuz A Abstract Various drugs are known to cause pill esophagitis. Antimicrobial drugs and nonsteroidal anti-inflammatory drugs are the most common causes of pill-induced esophagitis. Most patients suffer only self-limiting pain, but serious complications can occur. A 21-year-old man was admitted to our outpatient clinic with retrosternal chest pain, dys... περισσότερα »
Infected bronchogenic cyst causing dysphagia and retrosternal pain.
[image: http:--media.wiley.com-assets-7315-19-Wi] Related Articles *Infected bronchogenic cyst causing dysphagia and retrosternal pain.* Clin Respir J. 2013 Apr;7(2):e13-4 Authors: Søndergaard EB, Pedersen JH, Kleive D Abstract Bronchogenic cysts are congenital. They are typically discovered in infancy or early childhood. Secondary infection of the cyst is uncommon. We present the case of a 17-year-old female who presented to the emergency department with intermediate onset of upper abdominal, and retrosternal chest pain and fever. Subsequent X-ray and computerised tomography scan ... περισσότερα »
Dysphagia and Dysphonia Assessment Tools After Anterior Cervical Spine Surgery.
*Dysphagia and Dysphonia Assessment Tools After Anterior Cervical Spine Surgery.* Clin Spine Surg. 2016 Mar 11; Authors: Rosenthal BD, Nair R, Hsu WK, Patel AA, Savage JW Abstract The Smith-Robinson approach to the anterior cervical spine is being increasingly used, but it is not without complication. Dysphagia and dysphonia are the most common complications of the procedure. Many classification systems have been developed to stage and grade postoperative dysphagia and dysphonia, but inconsistent usage and lack of consensus adoption has limited research progress. A discussion of ... περισσότερα »
The South African dysphagia screening tool (SADS): A screening tool for a developing context.
*The South African dysphagia screening tool (SADS): A screening tool for a developing context.* S Afr J Commun Disord. 2016;63(1):e1-e9 Authors: Ostrofsky C, Seedat J Abstract BACKGROUND: Notwithstanding its value, there are challenges and limitations to implementing a dysphagia screening tool from a developed contexts in a developing context. The need for a reliable and valid screening tool for dysphagia that considers context, systemic rules and resources was identified to prevent further medical compromise, optimise dysphagia prognosis and ultimately hasten patients' return to... περισσότερα »
Implementing oral care to reduce aspiration pneumonia amongst patients with dysphagia in a South African setting.
*Implementing oral care to reduce aspiration pneumonia amongst patients with dysphagia in a South African setting.* S Afr J Commun Disord. 2016;63(1):e1-e11 Authors: Seedat J, Penn C Abstract Oral care is a crucial routine for patients with dysphagia that, when completed routinely, can prevent the development of aspiration pneumonia. There is no standardised protocol for oral care within government hospitals in South Africa. This study aimed to investigate the outcome of an oral care protocol. Participants were patients with oropharyngeal dysphagia, with either stroke or traumati... περισσότερα »
Pulmonary rehabilitation and oral nutritional supplement enriched with beta-hydroxy-beta-methylbutyrate for bronchiectasis participants: A prospective, randomised study.
*Pulmonary rehabilitation and oral nutritional supplement enriched with beta-hydroxy-beta-methylbutyrate for bronchiectasis participants: A prospective, randomised study.* Clin Nutr. 2016 Feb 6; Authors: Kokura Y, Maeda K, Wakabayashi H PMID: 26972090 [PubMed - as supplied by publisher] from Swallowing and Swallowing Disorders (Dysphagia) via xlomafota13 on Inoreader http://ift.tt/22i9TZ7
A cohort study of the morbidity of combined anterior-posterior cervical spinal fusions: incidence and predictors of postoperative dysphagia.
*A cohort study of the morbidity of combined anterior-posterior cervical spinal fusions: incidence and predictors of postoperative dysphagia.* Eur Spine J. 2016 Mar 14; Authors: Reinard KA, Cook DM, Zakaria HM, Basheer AM, Chang VW, Abdulhak MM Abstract PURPOSE: To identify risk factors that may lead to the development of dysphagia after combined anterior and posterior (360°) cervical fusion surgery. METHODS: A single center, retrospective analysis of patients who had same-day, 360° fusion at Henry Ford Hospital between 2008 and 2012 was performed. Variables analyzed included demo... περισσότερα »
Interpretation of an Extended Autoantibody Profile in a Well-Characterized Australian Systemic Sclerosis (Scleroderma) Cohort Using Principal Components Analysis.
[image: http:--media.wiley.com-assets-7315-19-Wi] Related Articles *Interpretation of an Extended Autoantibody Profile in a Well-Characterized Australian Systemic Sclerosis (Scleroderma) Cohort Using Principal Components Analysis.* Arthritis Rheumatol. 2015 Dec;67(12):3234-44 Authors: Patterson KA, Roberts-Thomson PJ, Lester S, Tan JA, Hakendorf P, Rischmueller M, Zochling J, Sahhar J, Nash P, Roddy J, Hill C, Nikpour M, Stevens W, Proudman SM, Walker JG Abstract OBJECTIVE: To determine the relationships between systemic sclerosis (SSc)-related autoantibodies, as well as their cli... περισσότερα »
Precision prevention of oesophageal adenocarcinoma.
[image: http:--http://ift.tt/1OOTDZp] [image: http:--http://ift.tt/1Fkw4zC] Related Articles *Precision prevention of oesophageal adenocarcinoma.* Nat Rev Gastroenterol Hepatol. 2015 Apr;12(4):243-8 Authors: Vaughan TL, Fitzgerald RC Abstract The incidence of oesophageal adenocarcinoma has risen rapidly over the past four decades. Unfortunately, treatments have not kept pace; unless their cancer is identified at a very early stage, most patients will not survive a year after diagnosis. The beginnings of this widespread problem were first recognized over 25 years ago, yet rates hav... περισσότερα »
Pediatric Maxillofacial Trauma
: a Review of 156 Patients via Oral and Maxillofacial Surgery Publication date: Available online 12 March 2016 *Source:*Journal of Oral and Maxillofacial Surgery Author(s): Al Haitham Al Shetawi, C. Anthoney Lim, Yash K. Singh, Jason E. Portnof, Stephen M. Blumberg PurposeTo review the epidemiology and management of facial fractures in a pediatric population.Materials and MethodsRetrospective review of patients under 18 years old presenting to a pediatric emergency department over a 5-year period in an urban, academic, Level-1 designated trauma center.Results156 patients were identifie... περισσότερα »
Low level laser therapy (LLLT) on reducing pain and swelling
Is low level laser therapy effective in management of pain and swelling after mandibular third molar surgery via Oral and Maxillofacial Surgery Publication date: Available online 12 March 2016 *Source:*Journal of Oral and Maxillofacial Surgery Author(s): Majid Eshghpour, Farzaneh Ahrari, Mohammad Takallu PurposeThis study was conducted to evaluate the effect of low level laser therapy (LLLT) on reducing pain and swelling following removal of impacted third molars.MethodsThis randomized, double blind, split-mouth designed study included patients presenting two symmetrically impacted mand...περισσότερα »
Statin intake is associated with reduced PPD in diabetic patients and MMP-1 level in GCF in either nondiabetic or diabetic patients.
Statin Intake Is Associated with MMP-1 Level in Gingival Crevicular Fluid of Patients with Periodontitis: [image: cover.gif?v=1&s=27703ad39525d3c4795e45b7] Abstract background This study was conducted to assess if statin intake is associated with clinical parameters of periodontitis and matrix metalloproteinase (MMP) levels in gingival crevicular fluid (GCF) of nondiabetic and diabetic patients. methods We first determined the effect of simvastatin on MMP expression in mononuclear cells. We then recruited 117 nondiabetic and diabetic patients, who all had periodontitis and took ... περισσότερα »
Characterizing patterns of endothelialization following coil embolization: a whole-mount, dual immunostaining approach
Background The extent, rate, and source of endothelialization following coil embolization of saccular aneurysms remains poorly understood. We performed a whole tissue mount, dual immunohistochemical analysis of experimental aneurysms to characterize the state of endothelialization over time after platinum coil embolization. Method and material Elastase-induced rabbit aneurysms were created and treated with bare platinum coils. Samples were harvested at 4 and 8 weeks (n=6 for each). En face whole tissue mount staining with antibodies to CD31 and α-smooth muscle actin was used to... περισσότερα »
Enrollment bias: frequency and impact on patient selection in endovascular stroke trials
Background Selection bias may have affected enrollment in first generation endovascular stroke trials. We investigate, evaluate, and quantify such bias for these trials at our institution. Methods Demographic, clinical, imaging, and angiographic data were prospectively collected on a consecutive cohort of patients with acute ischemic stroke who were enrolled in formal trials of endovascular stroke therapy (EST) or received EST in clinical practice outside of a randomized trial for acute cerebral ischemia at a single tertiary referral center from September 2004 to December 2012.... περισσότερα »
Stent retriever thrombectomy with the Cover accessory device versus proximal protection with a balloon guide catheter: in vitro stroke model comparison
Background Recently, an in vitro cerebrovascular occlusion model of the intracranial circulation was developed for testing thrombectomy devices. The Cover accessory (Lazarus Effect; Campbell, California, USA) is a novel nitinol braided mesh device that surrounds the stent retrieval device and thrombus during the retrieval process to help prevent clot fragmentation and embolization. Methods Using the in vitro model, after introducing fresh clot into the middle cerebral artery, we compared rates of target vessel recanalization and embolization in new territories (areas in which c... περισσότερα »
The Dotter method revisited: early experience with a novel method of rapid internal carotid artery revascularization in the setting of acute ischemic stroke
Background Tandem occlusive disease in the setting of acute ischemic stroke involving cervical and cerebral arteries has been associated with poor neurological outcome and poses significant challenges to neurointerventionists. Previously described endovascular methods typically involve carotid revascularization with stent placement prior to or following intracranial thrombectomy. Stent-based approaches, however, require the use of antiplatelet therapy which may increase the risk of hemorrhagic transformation. We describe a novel modified Dotter technique which may be used for ca... περισσότερα »
Intravenous thrombolysis of large vessel occlusions is associated with higher hospital costs than small vessel strokes: a rationale for developing stroke severity-based financial models
Background Owing to their severity, large vessel occlusion (LVO) strokes may be associated with higher costs that are not reflected in current coding systems. This study aimed to determine whether intravenous thrombolysis costs are related to the presence or absence of LVO. Methods Patients who had undergone intravenous thrombolysis over a 9-year period were divided into LVO and no LVO (nLVO) groups based on admission CT angiography. The primary outcome was hospital cost per admission. Secondary outcomes included admission duration, 90-day clinical outcome, and discharge destin...περισσότερα »
Xerostomia
: Current streams of investigation via Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology Publication date: Available online 14 March 2016 *Source:*Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology Author(s): Ryan L. Quock Xerostomia is the subjective patient feeling of dry mouth, and it is often related to salivary hypofunction. Aside from medication-related salivary hypofunction, Sjogren’s syndrome and head-and-neck radiation are two common etiologies that have garnered considerable attention. Approaches to treating and/or preventing salivary hypofunction in ... περισσότερα »
Les pathologies de la muqueuse buccale (PMB)
Étude épidémiologique des pathologies de la muqueuse buccale dans une consultation spécialisée de centre hospitalo-universitaire (CHU) via Revue de Stomatologie, de Chirurgie Maxillo-faciale et de Chirurgie Orale Publication date: Available online 14 March 2016 *Source:*Revue de Stomatologie, de Chirurgie Maxillo-faciale et de Chirurgie Orale Author(s): E. Massereau, R. Laurans, J.-M. Foletti, A. Gallucci, C. Chossegros IntroductionLes pathologies de la muqueuse buccale (PMB) sont fréquentes et concernent, selon les études, 2,5 à 61,6 % de la population générale. L’objectif principal ...περισσότερα »
Study design for the fostering eating after stroke with transcranial direct current stimulation trial: a randomized controlled intervention for improving Dysphagia after acute ischemic stroke.
[image: http:--linkinghub.elsevier.com-ihub-imag] [image: http:--http://ift.tt/1Fkw4zC] Related Articles *Study design for the fostering eating after stroke with transcranial direct current stimulation trial: a randomized controlled intervention for improving Dysphagia after acute ischemic stroke.* J Stroke Cerebrovasc Dis. 2015 Mar;24(3):511-20 Authors: Marchina S, Schlaug G, Kumar S Abstract GOAL: Dysphagia is a major stroke complication but lacks effective therapy that can promote recovery. Noninvasive brain stimulation with and without peripheral sensorimotor activities may b... περισσότερα »
Esophagitis due to dexketoprofen trometamol: a rare case report.
[image: http:--production.springer.de-OnlineReso] Related Articles *Esophagitis due to dexketoprofen trometamol: a rare case report.* Wien Klin Wochenschr. 2015 May;127(9-10):399-401 Authors: Olmez S, Donmez S, Aslan M, Karadas S, Yavuz A Abstract Various drugs are known to cause pill esophagitis. Antimicrobial drugs and nonsteroidal anti-inflammatory drugs are the most common causes of pill-induced esophagitis. Most patients suffer only self-limiting pain, but serious complications can occur. A 21-year-old man was admitted to our outpatient clinic with retrosternal chest pain, dy... περισσότερα »
Infected bronchogenic cyst causing dysphagia and retrosternal pain.
[image: http:--media.wiley.com-assets-7315-19-Wi] Related Articles *Infected bronchogenic cyst causing dysphagia and retrosternal pain.* Clin Respir J. 2013 Apr;7(2):e13-4 Authors: Søndergaard EB, Pedersen JH, Kleive D Abstract Bronchogenic cysts are congenital. They are typically discovered in infancy or early childhood. Secondary infection of the cyst is uncommon. We present the case of a 17-year-old female who presented to the emergency department with intermediate onset of upper abdominal, and retrosternal chest pain and fever. Subsequent X-ray and computerised tomography scan... περισσότερα »
Dysphagia and Dysphonia Assessment Tools After Anterior Cervical Spine Surgery.
*Dysphagia and Dysphonia Assessment Tools After Anterior Cervical Spine Surgery.* Clin Spine Surg. 2016 Mar 11; Authors: Rosenthal BD, Nair R, Hsu WK, Patel AA, Savage JW Abstract The Smith-Robinson approach to the anterior cervical spine is being increasingly used, but it is not without complication. Dysphagia and dysphonia are the most common complications of the procedure. Many classification systems have been developed to stage and grade postoperative dysphagia and dysphonia, but inconsistent usage and lack of consensus adoption has limited research progress. A discussion of ... περισσότερα »
The South African dysphagia screening tool (SADS): A screening tool for a developing context.
*The South African dysphagia screening tool (SADS): A screening tool for a developing context.* S Afr J Commun Disord. 2016;63(1):e1-e9 Authors: Ostrofsky C, Seedat J Abstract BACKGROUND: Notwithstanding its value, there are challenges and limitations to implementing a dysphagia screening tool from a developed contexts in a developing context. The need for a reliable and valid screening tool for dysphagia that considers context, systemic rules and resources was identified to prevent further medical compromise, optimise dysphagia prognosis and ultimately hasten patients' return to... περισσότερα »
Implementing oral care to reduce aspiration pneumonia amongst patients with dysphagia in a South African setting.
*Implementing oral care to reduce aspiration pneumonia amongst patients with dysphagia in a South African setting.* S Afr J Commun Disord. 2016;63(1):e1-e11 Authors: Seedat J, Penn C Abstract Oral care is a crucial routine for patients with dysphagia that, when completed routinely, can prevent the development of aspiration pneumonia. There is no standardised protocol for oral care within government hospitals in South Africa. This study aimed to investigate the outcome of an oral care protocol. Participants were patients with oropharyngeal dysphagia, with either stroke or traumati... περισσότερα »
Pulmonary rehabilitation and oral nutritional supplement enriched with beta-hydroxy-beta-methylbutyrate for bronchiectasis participants: A prospective, randomised study.
*Pulmonary rehabilitation and oral nutritional supplement enriched with beta-hydroxy-beta-methylbutyrate for bronchiectasis participants: A prospective, randomised study.* Clin Nutr. 2016 Feb 6; Authors: Kokura Y, Maeda K, Wakabayashi H PMID: 26972090 [PubMed - as supplied by publisher] from Swallowing and Swallowing Disorders (Dysphagia) via a.lsfakia on Inoreader http://ift.tt/22i9TZ7 via IFTTT
A cohort study of the morbidity of combined anterior-posterior cervical spinal fusions: incidence and predictors of postoperative dysphagia.
*A cohort study of the morbidity of combined anterior-posterior cervical spinal fusions: incidence and predictors of postoperative dysphagia.* Eur Spine J. 2016 Mar 14; Authors: Reinard KA, Cook DM, Zakaria HM, Basheer AM, Chang VW, Abdulhak MM Abstract PURPOSE: To identify risk factors that may lead to the development of dysphagia after combined anterior and posterior (360°) cervical fusion surgery. METHODS: A single center, retrospective analysis of patients who had same-day, 360° fusion at Henry Ford Hospital between 2008 and 2012 was performed. Variables analyzed included demo... περισσότερα »
Interpretation of an Extended Autoantibody Profile in a Well-Characterized Australian Systemic Sclerosis (Scleroderma) Cohort Using Principal Components Analysis.
[image: http:--media.wiley.com-assets-7315-19-Wi] Related Articles *Interpretation of an Extended Autoantibody Profile in a Well-Characterized Australian Systemic Sclerosis (Scleroderma) Cohort Using Principal Components Analysis.* Arthritis Rheumatol. 2015 Dec;67(12):3234-44 Authors: Patterson KA, Roberts-Thomson PJ, Lester S, Tan JA, Hakendorf P, Rischmueller M, Zochling J, Sahhar J, Nash P, Roddy J, Hill C, Nikpour M, Stevens W, Proudman SM, Walker JG Abstract OBJECTIVE: To determine the relationships between systemic sclerosis (SSc)-related autoantibodies, as well as their cl... περισσότερα »
Precision prevention of oesophageal adenocarcinoma.
[image: http:--http://ift.tt/1OOTDZp] [image: http:--http://ift.tt/1Fkw4zC] Related Articles *Precision prevention of oesophageal adenocarcinoma.* Nat Rev Gastroenterol Hepatol. 2015 Apr;12(4):243-8 Authors: Vaughan TL, Fitzgerald RC Abstract The incidence of oesophageal adenocarcinoma has risen rapidly over the past four decades. Unfortunately, treatments have not kept pace; unless their cancer is identified at a very early stage, most patients will not survive a year after diagnosis. The beginnings of this widespread problem were first recognized over 25 years ago, yet rates ha... περισσότερα »
speech and language; +18 new citations
18 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: *speech and language* These pubmed results were generated on 2016/03/15 PubMed comprises more than 24 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites. from Speech via a.lsfakia on Inoreader http://ift.tt/1QZSIV1 via IFTTT
Compound RYR1 heterozygosity resulting in a complex phenotype of malignant hyperthermia susceptibility and a core myopathy.
[image: http:--linkinghub.elsevier.com-ihub-imag] Related Articles *Compound RYR1 heterozygosity resulting in a complex phenotype of malignant hyperthermia susceptibility and a core myopathy.* Neuromuscul Disord. 2015 Jul;25(7):567-76 Authors: Kraeva N, Heytens L, Jungbluth H, Treves S, Voermans N, Kamsteeg E, Ceuterick-de Groote C, Baets J, Riazi S Abstract Malignant hyperthermia (MH) is a potentially fatal pharmacogenetic myopathy triggered by exposure to volatile anesthetics and/or depolarizing muscle relaxants. Susceptibility to MH is primarily associated with dominant mutati... περισσότερα »
Clinical, neuropathological and radiological evidence for a rare complication of rituximab therapy.
[image: http:--linkinghub.elsevier.com-ihub-imag] Related Articles *Clinical, neuropathological and radiological evidence for a rare complication of rituximab therapy.* Neuromuscul Disord. 2015 Jul;25(7):589-92 Authors: Healy EG, Phadke R, Kidd M, Reilly MM, Lunn MP Abstract We report a rare case of myofasciitis and meningitis with deafness caused by systemic enterovirus infection in the setting of hypogammaglobulinaemia induced by rituximab. Whilst effective and generally safe, anti- CD 20 antibody therapy is increasingly recognised to result in unusual infectious complications ... περισσότερα »
The Preclinical and Clinical Effects of Vilazodone for the Treatment of Major Depressive Disorder.
*The Preclinical and Clinical Effects of Vilazodone for the Treatment of Major Depressive Disorder.* Expert Opin Drug Discov. 2016 Mar 14; Authors: Sahli ZT, Banerjee P, Tarazi FI Abstract INTRODUCTION: Major depressive disorder (MDD) is the leading cause of disability worldwide, and according to the STAR*D trial, only 33% of patients with MDD responded to initial drug therapy. Augmentation of the leading class of antidepressant treatment, selective serotonin reuptake inhibitors (SSRIs), with the 5-HT1A receptor agonist buspirone has been shown to be effective in treating patient... περισσότερα »
The development of high-content screening (HCS) technology and its importance to drug discovery.
*The development of high-content screening (HCS) technology and its importance to drug discovery.* Expert Opin Drug Discov. 2016 Mar 14; Authors: Fraietta I, Gasparri F Abstract INTRODUCTION: High-content screening (HCS) was introduced about twenty years ago as a promising analytical approach to facilitate some critical aspects of drug discovery. Its application has spread progressively within the pharmaceutical industry and academia to the point that it today represents a fundamental tool in supporting drug discovery and development. Areas covered: Here, the authors review some ... περισσότερα »
Metabolic phenotype of bladder cancer.
*Metabolic phenotype of bladder cancer.* Cancer Treat Rev. 2016 Mar 8;45:46-57 Authors: Massari F, Ciccarese C, Santoni M, Iacovelli R, Mazzucchelli R, Piva F, Scarpelli M, Berardi R, Tortora G, Lopez-Beltran A, Cheng L, Montironi R Abstract Metabolism of bladder cancer represents a key issue for cancer research. Several metabolic altered pathways are involved in bladder tumorigenesis, representing therefore interesting targets for therapy. Tumor cells, including urothelial cancer cells, rely on a peculiar shift to aerobic glycolysis-dependent metabolism (the Warburg-effect) as t... περισσότερα »
Survival of patients with metastatic melanoma and brain metastases in the era of MAP-kinase inhibitors and immunologic checkpoint blockade antibodies: A systematic review.
*Survival of patients with metastatic melanoma and brain metastases in the era of MAP-kinase inhibitors and immunologic checkpoint blockade antibodies: A systematic review.* Cancer Treat Rev. 2016 Mar 8;45:38-45 Authors: Spagnolo F, Picasso V, Lambertini M, Ottaviano V, Dozin B, Queirolo P Abstract BACKGROUND: The incidence of brain metastases (BM) in melanoma patients is common and associated with poor prognosis. MAP-kinase inhibitors and immunologic checkpoint blockade antibodies led to improved survival of metastatic melanoma patients; however, patients with BM are under-repr... περισσότερα »
MYB-fusions and other potential actionable targets in adenoid cystic carcinoma.
*MYB-fusions and other potential actionable targets in adenoid cystic carcinoma.* Curr Opin Oncol. 2016 Mar 11; Authors: Ferrarotto R, Heymach JV, Glisson BS Abstract PURPOSE OF REVIEW: Adenoid cystic carcinoma (ACC) is a rare cancer of the secretory glands, typically originating in the salivary glands of the head and neck. The impact of chemotherapy on survival is unclear and there are no standard-of-care treatments for patients with recurrent or metastatic disease. This article reviews recently completed and ongoing clinical trials for patients with ACC and describes recently i... περισσότερα »
Management of advanced nodal disease in patients treated with primary chemoradiotherapy.
*Management of advanced nodal disease in patients treated with primary chemoradiotherapy.* Curr Opin Oncol. 2016 Mar 11; Authors: Mehanna H, Wong WL, Dunn J Abstract PURPOSE OF REVIEW: The management of advanced nodal disease in patients treated with chemoradiotherapy has been a controversial topic for many years. New data have recently been reported, including the results of a multicentre randomized trial making this review timely. RECENT FINDINGS: The PET NECK trial showed that PET-computer tomography (CT) surveillance is as effective as planned neck dissection in terms of over... περισσότερα »
Sodium Selenite Acts as an Otoprotectant against Neomycin-Induced Hair Cell Damage in a Zebrafish Model.
*Sodium Selenite Acts as an Otoprotectant against Neomycin-Induced Hair Cell Damage in a Zebrafish Model.* PLoS One. 2016;11(3):e0151557 Authors: Chang J, Choi J, Rah YC, Yoo MH, Oh KH, Im GJ, Lee SH, Kwon SY, Park HC, Chae SW, Jung HH Abstract Sodium selenite is a trace element essential for many physiological functions in the body. It is involved in various biological processes; it acts as a cofactor for antioxidant enzymes that protect against free radicals and is reported to limit metal-mediated oxidative DNA damage. In the present study, we investigated the effect of sodium ... περισσότερα »
Transcription Factors Expressed in Mouse Cochlear Inner and Outer Hair Cells.
*Transcription Factors Expressed in Mouse Cochlear Inner and Outer Hair Cells.* PLoS One. 2016;11(3):e0151291 Authors: Li Y, Liu H, Barta CL, Judge PD, Zhao L, Zhang WJ, Gong S, Beisel KW, He DZ Abstract Regulation of gene expression is essential to determining the functional complexity and morphological diversity seen among different cells. Transcriptional regulation is a crucial step in gene expression regulation because the genetic information is directly read from DNA by sequence-specific transcription factors (TFs). Although several mouse TF databases created from genome se...περισσότερα »
The Influence of Linguistic Proficiency on Masked Text Recognition Performance in Adults With and Without Congenital Hearing Impairment.
*The Influence of Linguistic Proficiency on Masked Text Recognition Performance in Adults With and Without Congenital Hearing Impairment.* Ear Hear. 2016 Mar 11; Authors: Huysmans E, Bolk E, Zekveld AA, Festen JM, de Groot AM, Goverts ST Abstract OBJECTIVE: The authors first examined the influence of moderate to severe congenital hearing impairment (CHI) on the correctness of samples of elicited spoken language. Then, the authors used this measure as an indicator of linguistic proficiency and examined its effect on performance in language reception, independent of bottom-up audito...περισσότερα »
Bilateral Vestibular Hypofunction: Insights in Etiologies, Clinical Subtypes, and Diagnostics.
*Bilateral Vestibular Hypofunction: Insights in Etiologies, Clinical Subtypes, and Diagnostics.* Front Neurol. 2016;7:26 Authors: Lucieer F, Vonk P, Guinand N, Stokroos R, Kingma H, van de Berg R Abstract OBJECTIVE: To evaluate the different etiologies and clinical subtypes of bilateral vestibular hypofunction (BVH) and the value of diagnostic tools in the diagnostic process of BVH. MATERIALS AND METHODS: A retrospective case review was performed on 154 patients diagnosed with BVH in a tertiary referral center, between 2013 and 2015. Inclusion criteria comprised (1) imbalance and/...περισσότερα »
Effects of Hearing Loss and Cognitive Load on Speech Recognition with Competing Talkers.
*Effects of Hearing Loss and Cognitive Load on Speech Recognition with Competing Talkers.* Front Psychol. 2016;7:301 Authors: Meister H, Schreitmüller S, Ortmann M, Rählmann S, Walger M Abstract Everyday communication frequently comprises situations with more than one talker speaking at a time. These situations are challenging since they pose high attentional and memory demands placing cognitive load on the listener. Hearing impairment additionally exacerbates communication problems under these circumstances. We examined the effects of hearing loss and attention tasks on speech r... περισσότερα »
Deficits in the Sensitivity to Pitch Sweeps by School-Aged Children Wearing Cochlear Implants.
*Deficits in the Sensitivity to Pitch Sweeps by School-Aged Children Wearing Cochlear Implants.* Front Neurosci. 2016;10:73 Authors: Deroche ML, Kulkarni AM, Christensen JA, Limb CJ, Chatterjee M Abstract Sensitivity to static changes in pitch has been shown to be poorer in school-aged children wearing cochlear implants (CIs) than children with normal hearing (NH), but it is unclear whether this is also the case for dynamic changes in pitch. Yet, dynamically changing pitch has considerable ecological relevance in terms of natural speech, particularly aspects such as intonation, e...περισσότερα »
Primary Oral Malignancy Imitating Peri-Implantitis.
*Primary Oral Malignancy Imitating Peri-Implantitis.* J Oral Maxillofac Surg. 2016 Feb 18; Authors: Raiser V, Abu-El Naaj I, Shlomi B, Fliss DM, Kaplan I Abstract PURPOSE: To describe new cases of primary malignancy arising around dental implants. MATERIALS AND METHODS: Three patients presented with asymptomatic lesions around longstanding dental implants that resembled peri-implantitis. One case was primary large B-cell lymphoma and the remaining cases were primary squamous cell carcinoma in patients with oral lichen planus. The literature was reviewed for cases mimicking peri-im... περισσότερα »
Counseling Is Effective for Smoking Cessation in Head and Neck Cancer Patients-A Systematic Review and Meta-Analysis.
*Counseling Is Effective for Smoking Cessation in Head and Neck Cancer Patients-A Systematic Review and Meta-Analysis.* J Oral Maxillofac Surg. 2016 Feb 18; Authors: Klemp I, Steffenssen M, Bakholdt V, Thygesen T, Sørensen JA Abstract PURPOSE: The purpose of this systematic review was to describe the efficacy of smoking cessation counseling and the resulting quit rate in patients with head and neck cancer. MATERIALS AND METHODS: A systematic literature search was conducted in the PubMed, Embase, and Cochrane databases. Predictor variables were smoking cessation counseling and smok... περισσότερα »
Treatment and survival of second primary early-stage lung cancer, following treatment of head and neck cancer in the Netherlands.
*Treatment and survival of second primary early-stage lung cancer, following treatment of head and neck cancer in the Netherlands.* Lung Cancer. 2016 Apr;94:54-60 Authors: Louie AV, Damhuis RA, Haasbeek CJ, Warner A, Rodin D, Slotman BJ, Leemans CR, Senan S Abstract OBJECTIVES: The goal of this study was to evaluate treatment patterns and outcomes in early stage (ES) second primary lung cancer (SPLC) after head and neck squamous cell cancer (HNSCC), in the Netherlands. METHODS AND MATERIALS: Details of patients diagnosed between 1997 and 2011 with either an ES primary, or a SPLC a... περισσότερα »
Neck stoma patients: is vital information displayed at the bedside?
*Neck stoma patients: is vital information displayed at the bedside?* Br J Nurs. 2016 Mar 10;25(5):242-7 Authors: Darr A, Siddiq S, Jolly K, Spinou C Abstract Tracheostomies are common procedures in head and neck and critical care practice, with 50% of airway-related deaths attributable to complications such as occlusion or displacement. The National Tracheostomy Safety Project (NTSP) published guidance regarding emergency management of neck stoma patients. A prospective multicentre regional audit of all neck stoma inpatients (ward and intensive care unit (ICU) settings) was condu...περισσότερα »
Effect of vocal fold asymmetries on glottal flow.
*Effect of vocal fold asymmetries on glottal flow.* Laryngoscope. 2016 Mar 12; Authors: Oren L, Khosla S, Gutmark E Abstract OBJECTIVES/HYPOTHESIS: Voice disorders, such as unilateral vocal fold paralysis or paresis, and vocal fold scarring feature structural asymmetries of the vocal folds. Studies on how structural asymmetries affect voice has mostly been limited to computational simulations and experiments on mechanical models. The purpose of the current study is to examine the effects of asymmetries in left-right position, height, and length of the vocal folds on the intraglot... περισσότερα »
Mycobacterium ulcerans disease in the middle belt of Ghana: An eight-year review from six endemic districts.
*Mycobacterium ulcerans disease in the middle belt of Ghana: An eight-year review from six endemic districts.* Int J Mycobacteriol. 2015 Jun;4(2):138-42 Authors: Adu EJ, Ampadu E Abstract BACKGROUND: Mycobacterium ulcerans (MU) produces mycolactone toxin when infected with a plasmid. Toxin is cytotoxic and immunosuppressive, causing extensive destruction of tissues, leading to large ulcers on exposed parts of the body. Spontaneous healing by secondary intention leads to contractures, subluxation of joints, disuse atrophy, distal lymphedema and other complications. The disease is ...περισσότερα »
First results of a novel adjustable-length ossicular reconstruction prosthesis in temporal bones.
*First results of a novel adjustable-length ossicular reconstruction prosthesis in temporal bones.* Laryngoscope. 2016 Mar 12; Authors: Gottlieb PK, Li X, Monfared A, Blevins N, Puria S Abstract OBJECTIVES/HYPOTHESIS: The performance of an ossicular replacement prosthesis (ORP) is influenced by its alignment and appropriate tension between the tympanic membrane and the stapes footplate. A novel ORP with a flexible element that potentially allows for length adjustment in situ is presented and tested for acoustic performance. STUDY DESIGN: Laser Doppler vibrometry in fresh human cad...περισσότερα »
Diverse clinical and laboratory manifestations of bilateral vestibulopathy.
*Diverse clinical and laboratory manifestations of bilateral vestibulopathy.* Laryngoscope. 2016 Mar 12; Authors: Moon M, Chang SO, Kim MB Abstract OBJECTIVES/HYPOTHESIS: To identify the clinical and laboratory characteristics of bilateral vestibulopathy (BVP) on the video head impulse test (vHIT). STUDY DESIGN: Retrospective chart analysis. METHODS: During 23 months, 1,789 patients with dizziness underwent vHIT in our tertiary referral hospital. Of these patients, 65 (3.6%) patients had bilaterally positive catch-up saccades. Based on the caloric test, 15 (group 1) had bilateral... περισσότερα »
Effectiveness of platelet-rich plasma as an adjunctive material to bone graft
Effectiveness of platelet-rich plasma as an adjunctive material to bone graft: a systematic review and meta-analysis of randomized controlled clinical trials: The use of platelet-rich plasma (PRP) has become a strategic therapy in tissue regeneration medicine. PRP represents a good source of growth factors. Due to this property, it has been considered a reliable adjunctive material in bone augmentation procedures, such as the sinus lift technique. The aim of this review was to assess the scientific evidence on the effectiveness of PRP as an adjunctive material in the sinus floor ele... περισσότερα »
Stimulation of the nitrate-nitrite-NO-metabolism by repeated lettuce juice consumption decreases gingival inflammation
Stimulation of the nitrate-nitrite-NO-metabolism by repeated lettuce juice consumption decreases gingival inflammation in periodontal recall patients: a randomized, double blinded, placebo controlled clinical trial: Abstract Aim This prospective, parallel group, two-armed, double-blind, placebo controlled randomized trial evaluated the impact of dietary nitrate consumption on gingival inflammation in periodontal recall patients. Materials and Methods 44 (23 test/ 21 placebo) periodontal recall patients with chronic gingivitis were enrolled. At baseline Gingival Index (GI), Plaque Con... περισσότερα »
Pretreatment oral hygiene habits and survival of head and neck squamous cell carcinoma (HNSCC) patients
Pretreatment oral hygiene habits and survival of head and neck squamous cell carcinoma (HNSCC) patients: Abstract BackgroundThe survival time of patients with head and neck squamous cell carcinoma (HNSCC) is related to health behavior, such as tobacco smoking and alcohol consumption. Poor oral health (OH), dental care (DC) and the frequent use of mouthwash have been shown to represent independent risk factors for head and neck cancerogenesis, but their impact on the survival of HNSCC patients has not been systematically investigated. MethodsTwo hundred seventy-six incident HNSC...περισσότερα »
Immunotherapy for Head and Neck Squamous Cell Carcinoma
Immunotherapy for Head and Neck Squamous Cell Carcinoma: AbstractHead and neck squamous cell carcinoma has been found to be an immunosuppressive malignancy, with many defects in the host immune system contributing to the progression of disease. A greater understanding of these defects has lead to the identification and investigation of new therapeutic strategies, targeting immune system dysfunction in an effort to improve the outcomes of this disease. This article provides a brief review of the knowledge regarding the immune defects present in head and neck cancer, as well as a rev... περισσότερα »
Osteogenic potential of rhBMP9 combined with a bovine-derived natural bone mineral scaffold compared to rhBMP2
Osteogenic potential of rhBMP9 combined with a bovine-derived natural bone mineral scaffold compared to rhBMP2: [image: cover.gif?v=1&s=87bf4a525ec3ddfbe594c784] Abstract Objectives Combination therapies of growth factors and scaffolds for bone tissue engineering are becoming routine for clinical use. BMP9 has previously been characterized as one of the most osteogenic inducers among the BMP superfamily; however, up until recently, BMP9 has only been available through adenovirus transfection experiments (gene therapy). While recombinant human (rh)BMP2 is regarded as the gold sta... περισσότερα »
Cell proliferation signal pathways: Acquired cholesteatoma epithelial hyperproliferation
Acquired cholesteatoma epithelial hyperproliferation: Roles of cell proliferation signal pathways: [image: cover.gif?v=1&s=91b5c09aa476055defd12367] Objectives/Hypothesis To review the recent cell proliferation signal pathways in the etiopathogenesis of acquired middle ear cholesteatoma. Data Sources PubMed (to September 2015). Review Methods Articles about cell proliferation signal pathways in the etiopathogenesis of acquired cholesteatoma and treatment advances were searched in the PubMed database, from which 73 were included in this review. Results The exact underlying cellular... περισσότερα »
Anteriorly Based Partial Thickness Sternocleidomastoid Muscle Flap Following Parotidectomy
Anteriorly Based Partial Thickness Sternocleidomastoid Muscle Flap Following Parotidectomy: AbstractThe anteriorly based partial thickness sternocleidomastoid (SCM) muscle flap is among the various methods described to correct parotidectomy defects, but its indications and limitations are not clearly demonstrated in several reports. This study was done to test the aesthetic outcome of this method, its indications and limitations. At Dr. Babasaheb Ambedkar Memorial hospital, Mumbai, 20 patients presenting with benign parotid tumors underwent parotidectomy. 16 underwent superficial p...περισσότερα »
Single-Stage Trans-mastoid Drainage of Otogenic Brain Abscess: A Single-Institution Experience
Single-Stage Trans-mastoid Drainage of Otogenic Brain Abscess: A Single-Institution Experience: AbstractBrain abscess is the ultimate otogenic complication, both in severity and difficulty of management. In developing countries with high incidence of cholesteatoma, brain abscess is not a rare complication. In India, brain abscesses constitute about 8 % of all intracranial lesions. The surgical treatment of brain abscess is very controversial. This prospective study was done in ENT department of a tertiary care hospital in Kolkata, during the period from May 2009 to April 2014. 22 s... περισσότερα »
Spontaneous reporting of Stevens-Johnson syndrome and toxic epidermal necrolysis associated with antiepileptic drugs.
[image: http:--www.europeanreview.org-free_full_] Authors: Ordoñez L, Salgueiro E, Jimeno FJ, Manso G Abstract OBJECTIVE: To assess the association between Stevens-Johnson syndrome (SJS)/ toxic epidermal necrolysis (TEN) and antiepileptics including the most recently authorized drugs. METHODS: In the Spanish Pharmacovigilance database, we searched for spontaneous reports of SJS or TEN associated with antiepileptic drugs and analysed: a) reporting odds ratio (ROR), b) age and gender of the patient, c) evolution, d) latency and recovery periods and e) presence or absence of other s... περισσότερα »
Candida strains isolated from patients with denture stomatitis
Production of virulence factors in Candida strains isolated from patients with denture stomatitis and control individuals.: Diagn Microbiol Infect Dis. 2016; Authors: Pereira CA, Domingues N, Araújo MI, Junqueira JC, Back-Brito GN, Jorge AO Abstract The aim of this study was to evaluate the production of virulence factors in Candida isolates from the oral cavities of 50 patients with different degrees of denture stomatitis (DS, type I, II and III) and 50 individuals without signs of DS. We evaluated the enzymatic and hemolytic activities, the biofilm formation, and the cell surfac... περισσότερα »
Early onset esophageal adenocarcinoma: a distinct molecular entity?
*Early onset esophageal adenocarcinoma: a distinct molecular entity?* Oncoscience. 2016;3(1):42-8 Authors: van Nistelrooij AM, van Marion R, PALGA-group, Biermann K, Spaander MC, van Lanschot JJ, Wijnhoven BP, Dinjens WN Abstract Esophageal adenocarcinoma (EAC) is typically diagnosed in elderly with a median age of 68 years. The incidence of EAC has been rising over the last decades, also among young adults. The aim of the study was to investigate whether early onset EAC is a distinct molecular entity. To identify early onset EACs, the nationwide network and registry of histo- and... περισσότερα »
Implantation of esophageal cancer onto post-dissection ulcer after gastric endoscopic submucosal dissection.
*Implantation of esophageal cancer onto post-dissection ulcer after gastric endoscopic submucosal dissection.* World J Gastroenterol. 2016 Mar 7;22(9):2855-60 Authors: Asai S, Takeshita K, Kano Y, Nakao E, Ichinona T, Fujimoto N, Akamine E, Mori T, Ogawa A Abstract A case in which implantation of esophageal squamous cell carcinoma onto a post-dissection gastric ulcer was strongly suspected is presented. A 72-year-old man with alcoholic liver cirrhosis underwent esophagogastroduodenoscopy (EGD). Esophageal cancer (EC) (Mt, 20 mm, 0-Is) and gastric cancer (GC) (antrum, 15 mm, 0-IIc... περισσότερα »
Esophageal squamous cell cancer in a highly endemic region.
*Esophageal squamous cell cancer in a highly endemic region.* World J Gastroenterol. 2016 Mar 7;22(9):2811-7 Authors: Asombang AW, Kayamba V, Lisulo MM, Trinkaus K, Mudenda V, Sinkala E, Mwanamakondo S, Banda T, Soko R, Kelly P Abstract AIM: To identify risk factors associated with esophageal cancer in Zambia and association between dietary intake and urinary 8-iso prostaglandin F2α (8-isoPGF2α). METHODS: We conducted a prospective, case control study at the University Teaching Hospital. Subjects included both individuals admitted to the hospital and those presenting for an outpat... περισσότερα »
Eastern Cooperative Oncology Group and American College of Radiology Imaging Network Randomized Phase 2 Trial of Neoadjuvant Preoperative Paclitaxel/Cisplatin/Radiation Therapy (RT) or Irinotecan/Cisplatin/RT in Esophageal Adenocarcinoma: Long-Term Outcome and Implications for Trial Design.
*Eastern Cooperative Oncology Group and American College of Radiology Imaging Network Randomized Phase 2 Trial of Neoadjuvant Preoperative Paclitaxel/Cisplatin/Radiation Therapy (RT) or Irinotecan/Cisplatin/RT in Esophageal Adenocarcinoma: Long-Term Outcome and Implications for Trial Design.* Int J Radiat Oncol Biol Phys. 2016 Mar 15;94(4):738-46 Authors: Kleinberg LR, Catalano PJ, Forastiere AA, Keller SM, Mitchel EP, Anne PR, Benson AB Abstract PURPOSE: Toxicity, pathologic complete response, and long-term outcomes are reported for the neoadjuvant therapies assessed in a random... περισσότερα »
Metabolic syndrome in relation to Barrett's esophagus and esophageal adenocarcinoma: Results from a large population-based case-control study in the Clinical Practice Research Datalink.
*Metabolic syndrome in relation to Barrett's esophagus and esophageal adenocarcinoma: Results from a large population-based case-control study in the Clinical Practice Research Datalink.* Cancer Epidemiol. 2016 Mar 9;42:9-14 Authors: Drahos J, Li L, Jick SS, Cook MB Abstract Gastroesophageal reflux disease (GERD) causes local chronic inflammation that increases risks of Barrett's esophagus (BE) and esophageal adenocarcinoma (EA), yet symptomatic GERD is absent in approximately half of all such patients. Obesity exacerbates GERD and is also a component of metabolic syndrome (MetS)... περισσότερα »
Clinical implications of endoscopic ultrasonography non-traversability in patients with locoregional esophageal cancer receiving multimodality therapy.
*Clinical implications of endoscopic ultrasonography non-traversability in patients with locoregional esophageal cancer receiving multimodality therapy.* Korean J Intern Med. 2016 Mar 14; Authors: Cho CJ, Song HJ, Lee GH, Choi KD, Kim YH, Ryu JS, Kim SB, Kim JH, Park SI, Jung HY Abstract Background/Aims: Approximately 30% of esophageal cancer (EC) patients cannot complete endoscopic ultrasonography (EUS) due to malignant stricture (EUS non-traversability). This study examines clinical implications of EUS non-traversability in patients with advanced locoregional squamous EC recei...περισσότερα »
Epigenetic field cancerization in gastrointestinal cancers.
*Epigenetic field cancerization in gastrointestinal cancers.* Cancer Lett. 2016 Mar 10; Authors: Baba Y, Ishimoto T, Kurashige J, Iwatsuki M, Sakamoto Y, Yoshida N, Watanabe M, Baba H Abstract Epigenetic alterations, including aberrant DNA methylation, play an important role in human cancer development. Importantly, epigenetic alterations are reversible and can be targets for therapy or chemoprevention for various types of human cancers. A field for cancerization, or a field defect, is formed by the accumulation of genetic and/or epigenetic alterations in normal-appearing tissues... περισσότερα »
Prognostic significance of FAM3C in esophageal squamous cell carcinoma.
Related Articles *Prognostic significance of FAM3C in esophageal squamous cell carcinoma.* Diagn Pathol. 2015;10:192 Authors: Zhu YH, Zhang B, Li M, Huang P, Sun J, Fu J, Guan XY Abstract BACKGROUND: Family with sequence similarity 3, member C (FAM3C) has been identified as a novel regulator in epithelial-mesenchymal transition (EMT) and metastatic progression. However, the role of FAM3C in esophageal squamous cell carcinoma (ESCC) remains unexplored. The purpose of present study is to illustrate the role of FAM3C in predicting outcomes of patients with ESCC. METHODS: FAM3C expre... περισσότερα »
Interpretation of an Extended Autoantibody Profile in a Well-Characterized Australian Systemic Sclerosis (Scleroderma) Cohort Using Principal Components Analysis.
Related Articles *Interpretation of an Extended Autoantibody Profile in a Well-Characterized Australian Systemic Sclerosis (Scleroderma) Cohort Using Principal Components Analysis.* Arthritis Rheumatol. 2015 Dec;67(12):3234-44 Authors: Patterson KA, Roberts-Thomson PJ, Lester S, Tan JA, Hakendorf P, Rischmueller M, Zochling J, Sahhar J, Nash P, Roddy J, Hill C, Nikpour M, Stevens W, Proudman SM, Walker JG Abstract OBJECTIVE: To determine the relationships between systemic sclerosis (SSc)-related autoantibodies, as well as their clinical associations, in a well-characterized Aust... περισσότερα »
[Endoscopic submucosal excavation (ESE) is a safe and useful technique for endoscopic removal of submucosal tumors of the stomach and the esophagus in selected cases].
Related Articles *[Endoscopic submucosal excavation (ESE) is a safe and useful technique for endoscopic removal of submucosal tumors of the stomach and the esophagus in selected cases].* Z Gastroenterol. 2015 Jun;53(6):573-8 Authors: Reinehr R Abstract Submucosal tumors of stomach and esophagus are often detected incidentally during endoscopy and further characterized by endoscopic ultrasonography. After risk estimation such submucosal tumors are either controlled by watchful waiting or surgically resected. Nevertheless, symptomatic submucosal tumors should be treated. Endoscopi... περισσότερα »
[Detection of early neoplasia in Barrett's oesophagus: focus attention on index endoscopy in short-segment-Barrett's oesophagus with random biopsies].
Related Articles *[Detection of early neoplasia in Barrett's oesophagus: focus attention on index endoscopy in short-segment-Barrett's oesophagus with random biopsies].* Z Gastroenterol. 2015 Jun;53(6):568-72 Authors: Behrens A, Pech O, Wuthnow E, Manner H, Pohl J, May A, Ell C Abstract BACKGROUND: Detecting early neoplasias in Barrett's oesophagus (BE) is challenging. Recent publications have been focusing on improving the detection of such lesions during Barrett's surveillance. However in a recently published Danish register study calculating the risk for cancer-development in... περισσότερα »
Interpretation of an Extended Autoantibody Profile in a Well-Characterized Australian Systemic Sclerosis (Scleroderma) Cohort Using Principal Components Analysis.
[image: http:--media.wiley.com-assets-7315-19-Wi] Related Articles *Interpretation of an Extended Autoantibody Profile in a Well-Characterized Australian Systemic Sclerosis (Scleroderma) Cohort Using Principal Components Analysis.* Arthritis Rheumatol. 2015 Dec;67(12):3234-44 Authors: Patterson KA, Roberts-Thomson PJ, Lester S, Tan JA, Hakendorf P, Rischmueller M, Zochling J, Sahhar J, Nash P, Roddy J, Hill C, Nikpour M, Stevens W, Proudman SM, Walker JG Abstract OBJECTIVE: To determine the relationships between systemic sclerosis (SSc)-related autoantibodies, as well as their cl... περισσότερα »
Precision prevention of oesophageal adenocarcinoma.
[image: http:--http://ift.tt/1OOTDZp] [image: http:--http://ift.tt/1Fkw4zC] Related Articles *Precision prevention of oesophageal adenocarcinoma.* Nat Rev Gastroenterol Hepatol. 2015 Apr;12(4):243-8 Authors: Vaughan TL, Fitzgerald RC Abstract The incidence of oesophageal adenocarcinoma has risen rapidly over the past four decades. Unfortunately, treatments have not kept pace; unless their cancer is identified at a very early stage, most patients will not survive a year after diagnosis. The beginnings of this widespread problem were first recognized over 25 years ago, yet rates ha... περισσότερα »
Herausforderungen im Gesundheitswesen relevant für die Komplementärmedizin
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 54 δευτερόλεπτα
Schweiz Z Ganzheitsmed from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1U3J1eg via IFTTT
Sociometric status and the attribution of intentions in a sample of adolescents with cerebral palsy.
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 54 δευτερόλεπτα
Sociometric status and the attribution of intentions in a sample of adolescents with cerebral palsy. Disabil Rehabil. 2016 Mar 12;:1-6 Authors: Voyer AP, Tessier R, Nadeau L Abstract Purpose To examine how cerebral palsy (CP) and sociometric status at age 10 explain the development of a cognitive bias across two groups of adolescents aged 15. […]
Investigating Preterm Care at the Facility Level: Stakeholder Qualitative Study in Central and Southern Malawi
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 54 δευτερόλεπτα
Abstract Objectives Malawi is estimated to have one of the highest preterm birth rates in the world. However, care of preterm infants at facility level in Malawi has not been explored. We aimed to explore the views of health stakeholders about the care of preterm infants in health facilities and the existence of any policy […]
Ascending vestibular drive is asymmetrically distributed to the inferior oblique motoneuron pools in a subset of hemispheric stroke survivors.
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 54 δευτερόλεπτα
Ascending vestibular drive is asymmetrically distributed to the inferior oblique motoneuron pools in a subset of hemispheric stroke survivors. Clin Neurophysiol. 2016 Apr;127(4):2022-30 Authors: Miller DM, Baker JF, Rymer WZ Abstract OBJECTIVE: Aberrant vestibular nuclear function is proposed to be a principle driver of limb muscle spasticity after stroke. Although spasticity does not manifest in […]
Contactable Non-responders Show Different Characteristics Compared to Lost to Follow-Up Participants: Insights from an Australian Longitudinal Birth Cohort Study
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 54 δευτερόλεπτα
Abstract Objective This research aims to identify predictors of attrition in a longitudinal birth cohort study in Australia and assess differences in baseline characteristics and responses in subsequent follow-up phases between contactable non-responders and uncontactable non-responders deemed “lost to follow-up (LTF)”. Methods 3368 women recruited from three public hospitals in Southeast Queensland and Northern New […]
Stirnhöhlen-Mediandrainage.
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 54 δευτερόλεπτα
Stirnhöhlen-Mediandrainage. Laryngorhinootologie. 2016 Mar;95(3):226-228 Authors: PMID: 26974203 [PubMed – as supplied by publisher] from #ENT-PubMed via ola Kala on Inoreader http://ift.tt/1M4nSO1 via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1Ud8Fg9 via IFTTT
Fast Food Intake in Relation to Employment Status, Stress, Depression, and Dietary Behaviors in Low-Income Overweight and Obese Pregnant Women
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 54 δευτερόλεπτα
Abstract Objective This study explored fast food intake as a potential mediator of the relationships among employment status; stress; depression; and fruit, vegetable, and fat intakes by race (African American vs. Non-Hispanic White) and body mass index (BMI category: overweight vs. obesity). Methods Low-income overweight and obese pregnant women (N = 332) were recruited from […]
Exazerbierte oropharyngeale Schmerzen mit rezidivierenden synkopalen Episoden.
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 54 δευτερόλεπτα
Exazerbierte oropharyngeale Schmerzen mit rezidivierenden synkopalen Episoden. Laryngorhinootologie. 2016 Mar;95(3):200-201 Authors: Kramer B, Schultz JD, Hülse R, Hörmann K, Cazan D PMID: 26974201 [PubMed – as supplied by publisher] from #ENT-PubMed via ola Kala on Inoreader http://ift.tt/1M4nQG0 via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1Wn2AeV via IFTTT
The Impact of WIC on Birth Outcomes: New Evidence from South Carolina
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 54 δευτερόλεπτα
Abstract Objectives To investigate the impact of the Special Supplemental Nutrition Program for Women, Infants and Children (WIC) on a variety of infant health outcomes using recent South Carolina Vital Statistics data (2004–2012). Methods To account for non-random WIC participation, the study relies on a maternal fixed effects estimation, due to the availability of unique […]
„Lustpille“ für Frauen mit marginaler Wirkung
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 54 δευτερόλεπτα
Vermindertes sexuelles Verlangen Eine umfassende Metaanalyse präsentiert eine mäßige Nutzen-Risiko-Bilanz für Flibanserin bei Frauen mit vermindertem sexuellem Verlangen: ein wenig mehr guter Sex gegen deutlich mehr Nebenwirkungen. from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1MjXevp via IFTTT
Clinical significance of plasmacytoid dendritic cells and myeloid-derived suppressor cells in melanoma.
[image: http:--http://ift.tt/1NMOrDk] [image: http:--http://ift.tt/1Fkw4zC] Related Articles *Clinical significance of plasmacytoid dendritic cells and myeloid-derived suppressor cells in melanoma.* J Transl Med. 2015;13:9 Authors: Chevolet I, Speeckaert R, Schreuer M, Neyns B, Krysko O, Bachert C, Van Gele M, van Geel N, Brochez L Abstract BACKGROUND: Immune markers in the peripheral blood of melanoma patients could provide prognostic information. However, there is currently no consensus on which circulating cell types have more clinical impact. We therefore evaluated myeloid-d... περισσότερα »
The mitogen-activated protein kinase pathway plays a critical role in regulating immunological properties of BRAF mutant cutaneous melanoma cells.
*The mitogen-activated protein kinase pathway plays a critical role in regulating immunological properties of BRAF mutant cutaneous melanoma cells.* Melanoma Res. 2016 Mar 11; Authors: Whipple CA, Boni A, Fisher JL, Hampton TH, Tsongalis GJ, Mellinger DL, Yan S, Tafe LJ, Brinckerhoff CE, Turk MJ, Mullins DW, Fadul CE, Ernstoff MS Abstract The advent of drugs targeting the mitogen-activated protein kinase (MAPK) pathway has markedly changed the treatment of advanced-stage melanoma harboring BRAF mutations. However, drug resistance, through mechanisms not well elucidated, often oc...περισσότερα »
Precision prevention of oesophageal adenocarcinoma.
[image: http:--http://ift.tt/1OOTDZp] [image: http:--http://ift.tt/1Fkw4zC] Related Articles *Precision prevention of oesophageal adenocarcinoma.* Nat Rev Gastroenterol Hepatol. 2015 Apr;12(4):243-8 Authors: Vaughan TL, Fitzgerald RC Abstract The incidence of oesophageal adenocarcinoma has risen rapidly over the past four decades. Unfortunately, treatments have not kept pace; unless their cancer is identified at a very early stage, most patients will not survive a year after diagnosis. The beginnings of this widespread problem were first recognized over 25 years ago, yet rates ha... περισσότερα »
speech and language; +18 new citations
18 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: *speech and language* These pubmed results were generated on 2016/03/15 PubMed comprises more than 24 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites. from #ENT via xlomafota13 on Inoreader http://ift.tt/1QZSIV1 via IFTTT
Interpretation of an Extended Autoantibody Profile in a Well-Characterized Australian Systemic Sclerosis (Scleroderma) Cohort Using Principal Components Analysis.
[image: http:--media.wiley.com-assets-7315-19-Wi] Related Articles *Interpretation of an Extended Autoantibody Profile in a Well-Characterized Australian Systemic Sclerosis (Scleroderma) Cohort Using Principal Components Analysis.* Arthritis Rheumatol. 2015 Dec;67(12):3234-44 Authors: Patterson KA, Roberts-Thomson PJ, Lester S, Tan JA, Hakendorf P, Rischmueller M, Zochling J, Sahhar J, Nash P, Roddy J, Hill C, Nikpour M, Stevens W, Proudman SM, Walker JG Abstract OBJECTIVE: To determine the relationships between systemic sclerosis (SSc)-related autoantibodies, as well as their cl... περισσότερα »
Precision prevention of oesophageal adenocarcinoma.
[image: http:--http://ift.tt/1OOTDZp] [image: http:--http://ift.tt/1Fkw4zC] Related Articles *Precision prevention of oesophageal adenocarcinoma.* Nat Rev Gastroenterol Hepatol. 2015 Apr;12(4):243-8 Authors: Vaughan TL, Fitzgerald RC Abstract The incidence of oesophageal adenocarcinoma has risen rapidly over the past four decades. Unfortunately, treatments have not kept pace; unless their cancer is identified at a very early stage, most patients will not survive a year after diagnosis. The beginnings of this widespread problem were first recognized over 25 years ago, yet rates ha... περισσότερα »
Study design for the fostering eating after stroke with transcranial direct current stimulation trial: a randomized controlled intervention for improving Dysphagia after acute ischemic stroke.
[image: http:--linkinghub.elsevier.com-ihub-imag] [image: http:--http://ift.tt/1Fkw4zC] Related Articles *Study design for the fostering eating after stroke with transcranial direct current stimulation trial: a randomized controlled intervention for improving Dysphagia after acute ischemic stroke.* J Stroke Cerebrovasc Dis. 2015 Mar;24(3):511-20 Authors: Marchina S, Schlaug G, Kumar S Abstract GOAL: Dysphagia is a major stroke complication but lacks effective therapy that can promote recovery. Noninvasive brain stimulation with and without peripheral sensorimotor activities may b... περισσότερα »
Esophagitis due to dexketoprofen trometamol: a rare case report.
[image: http:--production.springer.de-OnlineReso] Related Articles *Esophagitis due to dexketoprofen trometamol: a rare case report.* Wien Klin Wochenschr. 2015 May;127(9-10):399-401 Authors: Olmez S, Donmez S, Aslan M, Karadas S, Yavuz A Abstract Various drugs are known to cause pill esophagitis. Antimicrobial drugs and nonsteroidal anti-inflammatory drugs are the most common causes of pill-induced esophagitis. Most patients suffer only self-limiting pain, but serious complications can occur. A 21-year-old man was admitted to our outpatient clinic with retrosternal chest pain, dy... περισσότερα »
Infected bronchogenic cyst causing dysphagia and retrosternal pain.
[image: http:--media.wiley.com-assets-7315-19-Wi] Related Articles *Infected bronchogenic cyst causing dysphagia and retrosternal pain.* Clin Respir J. 2013 Apr;7(2):e13-4 Authors: Søndergaard EB, Pedersen JH, Kleive D Abstract Bronchogenic cysts are congenital. They are typically discovered in infancy or early childhood. Secondary infection of the cyst is uncommon. We present the case of a 17-year-old female who presented to the emergency department with intermediate onset of upper abdominal, and retrosternal chest pain and fever. Subsequent X-ray and computerised tomography scan... περισσότερα »
Dysphagia and Dysphonia Assessment Tools After Anterior Cervical Spine Surgery.
*Dysphagia and Dysphonia Assessment Tools After Anterior Cervical Spine Surgery.* Clin Spine Surg. 2016 Mar 11; Authors: Rosenthal BD, Nair R, Hsu WK, Patel AA, Savage JW Abstract The Smith-Robinson approach to the anterior cervical spine is being increasingly used, but it is not without complication. Dysphagia and dysphonia are the most common complications of the procedure. Many classification systems have been developed to stage and grade postoperative dysphagia and dysphonia, but inconsistent usage and lack of consensus adoption has limited research progress. A discussion of ... περισσότερα »
The South African dysphagia screening tool (SADS): A screening tool for a developing context.
*The South African dysphagia screening tool (SADS): A screening tool for a developing context.* S Afr J Commun Disord. 2016;63(1):e1-e9 Authors: Ostrofsky C, Seedat J Abstract BACKGROUND: Notwithstanding its value, there are challenges and limitations to implementing a dysphagia screening tool from a developed contexts in a developing context. The need for a reliable and valid screening tool for dysphagia that considers context, systemic rules and resources was identified to prevent further medical compromise, optimise dysphagia prognosis and ultimately hasten patients' return to... περισσότερα »
Implementing oral care to reduce aspiration pneumonia amongst patients with dysphagia in a South African setting.
*Implementing oral care to reduce aspiration pneumonia amongst patients with dysphagia in a South African setting.* S Afr J Commun Disord. 2016;63(1):e1-e11 Authors: Seedat J, Penn C Abstract Oral care is a crucial routine for patients with dysphagia that, when completed routinely, can prevent the development of aspiration pneumonia. There is no standardised protocol for oral care within government hospitals in South Africa. This study aimed to investigate the outcome of an oral care protocol. Participants were patients with oropharyngeal dysphagia, with either stroke or traumati... περισσότερα »
Pulmonary rehabilitation and oral nutritional supplement enriched with beta-hydroxy-beta-methylbutyrate for bronchiectasis participants: A prospective, randomised study.
*Pulmonary rehabilitation and oral nutritional supplement enriched with beta-hydroxy-beta-methylbutyrate for bronchiectasis participants: A prospective, randomised study.* Clin Nutr. 2016 Feb 6; Authors: Kokura Y, Maeda K, Wakabayashi H PMID: 26972090 [PubMed - as supplied by publisher] from #ENT via xlomafota13 on Inoreader http://ift.tt/22i9TZ7 via IFTTT
A cohort study of the morbidity of combined anterior-posterior cervical spinal fusions: incidence and predictors of postoperative dysphagia.
*A cohort study of the morbidity of combined anterior-posterior cervical spinal fusions: incidence and predictors of postoperative dysphagia.* Eur Spine J. 2016 Mar 14; Authors: Reinard KA, Cook DM, Zakaria HM, Basheer AM, Chang VW, Abdulhak MM Abstract PURPOSE: To identify risk factors that may lead to the development of dysphagia after combined anterior and posterior (360°) cervical fusion surgery. METHODS: A single center, retrospective analysis of patients who had same-day, 360° fusion at Henry Ford Hospital between 2008 and 2012 was performed. Variables analyzed included demo... περισσότερα »
Interpretation of an Extended Autoantibody Profile in a Well-Characterized Australian Systemic Sclerosis (Scleroderma) Cohort Using Principal Components Analysis.
[image: http:--media.wiley.com-assets-7315-19-Wi] Related Articles *Interpretation of an Extended Autoantibody Profile in a Well-Characterized Australian Systemic Sclerosis (Scleroderma) Cohort Using Principal Components Analysis.* Arthritis Rheumatol. 2015 Dec;67(12):3234-44 Authors: Patterson KA, Roberts-Thomson PJ, Lester S, Tan JA, Hakendorf P, Rischmueller M, Zochling J, Sahhar J, Nash P, Roddy J, Hill C, Nikpour M, Stevens W, Proudman SM, Walker JG Abstract OBJECTIVE: To determine the relationships between systemic sclerosis (SSc)-related autoantibodies, as well as their cl... περισσότερα »
Precision prevention of oesophageal adenocarcinoma.
[image: http:--http://ift.tt/1OOTDZp] [image: http:--http://ift.tt/1Fkw4zC] Related Articles *Precision prevention of oesophageal adenocarcinoma.* Nat Rev Gastroenterol Hepatol. 2015 Apr;12(4):243-8 Authors: Vaughan TL, Fitzgerald RC Abstract The incidence of oesophageal adenocarcinoma has risen rapidly over the past four decades. Unfortunately, treatments have not kept pace; unless their cancer is identified at a very early stage, most patients will not survive a year after diagnosis. The beginnings of this widespread problem were first recognized over 25 years ago, yet rates ha... περισσότερα »
Human papillomavirus in tonsillar squamous cell carcinomas from Guatemala and Brazil.
Alexandros G. SfakianakisστοHead,Neck,Brain,Cervical Spine and Esophageal Cancers by Alexandros G. SfakianakisΠριν από 58 δευτερόλεπτα
*Human papillomavirus in tonsillar squamous cell carcinomas from Guatemala and Brazil.* Oral Surg Oral Med Oral Pathol Oral Radiol. 2016 Apr;121(4):412-8 Authors: Piña AR, Jimenez LS, Mariano FV, de Andrade BA, Carlos R, Altemani A, de Almeida OP Abstract OBJECTIVES: A subgroup of tonsillar squamous cell carcinoma (SCC) is associated with human papillomavirus (HPV). Nevertheless, the prevalence of HPV seems to be variable in different regions and ethnic groups. There are no reports of HPV in tonsillar carcinomas in Guatemala, and data from Brazil are scarce. The aim of this study...περισσότερα »
Diagnostic Difficulties in Pathological Laboratories in Developing Countries: A Case Report of Differentiated Squamous Cell Carcinoma in a Young Togolese Woman
Alexandros G. SfakianakisστοHead,Neck,Brain,Cervical Spine and Esophageal Cancers by Alexandros G. SfakianakisΠριν από 58 δευτερόλεπτα
We report a case of poorly differentiated squamous cell carcinoma of the vulva induced by human papillomavirus in a 23-year-old woman, in whom we experienced diagnostic difficulties. from squamous cell carcinoma via ok on Inoreader http://ift.tt/1V8OPlJ via IFTTT
Development of a new in-situ analysis technique applying luminescence of local coordination sensors: principle and application for monitoring metal-ligand exchange processes
[image: CrossMark.jpg] *Analyst*, 2016, Accepted Manuscript *DOI*: 10.1039/C6AN00075D, Paper Huayna Terraschke, Laura Ruiz Arana, Patric Lindenberg, Wolfgang Bensch Here, we introduce the principle of the novel *in-situ* luminescence analysis of coordination sensors (ILACS) approach for monitoring the formation of solid materials, recording information from the formed solid compounds... The content of this RSS Feed (c) The Royal Society of Chemistry from BioChemistry via xlomafota13 on Inoreader http://ift.tt/1pIxwMm via IFTTT
Acute Toxicity Grade 3 and 4 After Irradiation in Children and Adolescents
Acute Toxicity Grade 3 and 4 After Irradiation in Children and Adolescents: Results From the IPPARCA Collaboration.: Int J Radiat Oncol Biol Phys. 2016 Mar 15;94(4):792-9 Authors: Pixberg C, Koch R, Eich HT, Martinsson U, Kristensen I, Matuschek C, Kortmann RD, Pohl F, Elsayad K, Christiansen H, Willich N, Lindh J, Steinmann D Abstract PURPOSE: In the context of oncologic therapy for children, radiation therapy is frequently indicated. This study identified the frequency of and reasons for the development of high-grade acute toxicity and possible sequelae. MATERIALS AND METHODS: ...περισσότερα »
Sialendoscopy-assisted surgery and the chronic obstructive sialadenitis symptoms questionnaire: A prospective study.
*Sialendoscopy-assisted surgery and the chronic obstructive sialadenitis symptoms questionnaire: A prospective study.* Laryngoscope. 2016 Mar 12; Authors: Aubin-Pouliot A, Delagnes EA, Chang JL, Ryan WR Abstract OBJECTIVES/HYPOTHESIS: To prospectively assess symptoms of obstructive sialadenitis before and after sialendoscopy-assisted salivary duct surgery (SASDS) using the chronic obstructive sialadenitis symptoms (COSS) questionnaire to determine and predict impact of interventions. STUDY DESIGN: Prospective cohort study. METHODS: Adult patients with chronic obstructive sialadenit... περισσότερα »
MYB-fusions and other potential actionable targets in adenoid cystic carcinoma.
*MYB-fusions and other potential actionable targets in adenoid cystic carcinoma.* Curr Opin Oncol. 2016 Mar 11; Authors: Ferrarotto R, Heymach JV, Glisson BS Abstract PURPOSE OF REVIEW: Adenoid cystic carcinoma (ACC) is a rare cancer of the secretory glands, typically originating in the salivary glands of the head and neck. The impact of chemotherapy on survival is unclear and there are no standard-of-care treatments for patients with recurrent or metastatic disease. This article reviews recently completed and ongoing clinical trials for patients with ACC and describes recently i... περισσότερα »
Management of advanced nodal disease in patients treated with primary chemoradiotherapy.
*Management of advanced nodal disease in patients treated with primary chemoradiotherapy.* Curr Opin Oncol. 2016 Mar 11; Authors: Mehanna H, Wong WL, Dunn J Abstract PURPOSE OF REVIEW: The management of advanced nodal disease in patients treated with chemoradiotherapy has been a controversial topic for many years. New data have recently been reported, including the results of a multicentre randomized trial making this review timely. RECENT FINDINGS: The PET NECK trial showed that PET-computer tomography (CT) surveillance is as effective as planned neck dissection in terms of over... περισσότερα »
Sodium Selenite Acts as an Otoprotectant against Neomycin-Induced Hair Cell Damage in a Zebrafish Model.
*Sodium Selenite Acts as an Otoprotectant against Neomycin-Induced Hair Cell Damage in a Zebrafish Model.* PLoS One. 2016;11(3):e0151557 Authors: Chang J, Choi J, Rah YC, Yoo MH, Oh KH, Im GJ, Lee SH, Kwon SY, Park HC, Chae SW, Jung HH Abstract Sodium selenite is a trace element essential for many physiological functions in the body. It is involved in various biological processes; it acts as a cofactor for antioxidant enzymes that protect against free radicals and is reported to limit metal-mediated oxidative DNA damage. In the present study, we investigated the effect of sodium ... περισσότερα »
Transcription Factors Expressed in Mouse Cochlear Inner and Outer Hair Cells.
*Transcription Factors Expressed in Mouse Cochlear Inner and Outer Hair Cells.* PLoS One. 2016;11(3):e0151291 Authors: Li Y, Liu H, Barta CL, Judge PD, Zhao L, Zhang WJ, Gong S, Beisel KW, He DZ Abstract Regulation of gene expression is essential to determining the functional complexity and morphological diversity seen among different cells. Transcriptional regulation is a crucial step in gene expression regulation because the genetic information is directly read from DNA by sequence-specific transcription factors (TFs). Although several mouse TF databases created from genome se...περισσότερα »
The Influence of Linguistic Proficiency on Masked Text Recognition Performance in Adults With and Without Congenital Hearing Impairment.
*The Influence of Linguistic Proficiency on Masked Text Recognition Performance in Adults With and Without Congenital Hearing Impairment.* Ear Hear. 2016 Mar 11; Authors: Huysmans E, Bolk E, Zekveld AA, Festen JM, de Groot AM, Goverts ST Abstract OBJECTIVE: The authors first examined the influence of moderate to severe congenital hearing impairment (CHI) on the correctness of samples of elicited spoken language. Then, the authors used this measure as an indicator of linguistic proficiency and examined its effect on performance in language reception, independent of bottom-up audito...περισσότερα »
Bilateral Vestibular Hypofunction: Insights in Etiologies, Clinical Subtypes, and Diagnostics.
*Bilateral Vestibular Hypofunction: Insights in Etiologies, Clinical Subtypes, and Diagnostics.* Front Neurol. 2016;7:26 Authors: Lucieer F, Vonk P, Guinand N, Stokroos R, Kingma H, van de Berg R Abstract OBJECTIVE: To evaluate the different etiologies and clinical subtypes of bilateral vestibular hypofunction (BVH) and the value of diagnostic tools in the diagnostic process of BVH. MATERIALS AND METHODS: A retrospective case review was performed on 154 patients diagnosed with BVH in a tertiary referral center, between 2013 and 2015. Inclusion criteria comprised (1) imbalance and/...περισσότερα »
Effects of Hearing Loss and Cognitive Load on Speech Recognition with Competing Talkers.
*Effects of Hearing Loss and Cognitive Load on Speech Recognition with Competing Talkers.* Front Psychol. 2016;7:301 Authors: Meister H, Schreitmüller S, Ortmann M, Rählmann S, Walger M Abstract Everyday communication frequently comprises situations with more than one talker speaking at a time. These situations are challenging since they pose high attentional and memory demands placing cognitive load on the listener. Hearing impairment additionally exacerbates communication problems under these circumstances. We examined the effects of hearing loss and attention tasks on speech r... περισσότερα »
Deficits in the Sensitivity to Pitch Sweeps by School-Aged Children Wearing Cochlear Implants.
*Deficits in the Sensitivity to Pitch Sweeps by School-Aged Children Wearing Cochlear Implants.* Front Neurosci. 2016;10:73 Authors: Deroche ML, Kulkarni AM, Christensen JA, Limb CJ, Chatterjee M Abstract Sensitivity to static changes in pitch has been shown to be poorer in school-aged children wearing cochlear implants (CIs) than children with normal hearing (NH), but it is unclear whether this is also the case for dynamic changes in pitch. Yet, dynamically changing pitch has considerable ecological relevance in terms of natural speech, particularly aspects such as intonation, e...περισσότερα »
Primary Oral Malignancy Imitating Peri-Implantitis.
*Primary Oral Malignancy Imitating Peri-Implantitis.* J Oral Maxillofac Surg. 2016 Feb 18; Authors: Raiser V, Abu-El Naaj I, Shlomi B, Fliss DM, Kaplan I Abstract PURPOSE: To describe new cases of primary malignancy arising around dental implants. MATERIALS AND METHODS: Three patients presented with asymptomatic lesions around longstanding dental implants that resembled peri-implantitis. One case was primary large B-cell lymphoma and the remaining cases were primary squamous cell carcinoma in patients with oral lichen planus. The literature was reviewed for cases mimicking peri-im... περισσότερα »
Counseling Is Effective for Smoking Cessation in Head and Neck Cancer Patients-A Systematic Review and Meta-Analysis.
*Counseling Is Effective for Smoking Cessation in Head and Neck Cancer Patients-A Systematic Review and Meta-Analysis.* J Oral Maxillofac Surg. 2016 Feb 18; Authors: Klemp I, Steffenssen M, Bakholdt V, Thygesen T, Sørensen JA Abstract PURPOSE: The purpose of this systematic review was to describe the efficacy of smoking cessation counseling and the resulting quit rate in patients with head and neck cancer. MATERIALS AND METHODS: A systematic literature search was conducted in the PubMed, Embase, and Cochrane databases. Predictor variables were smoking cessation counseling and smok... περισσότερα »
Treatment and survival of second primary early-stage lung cancer, following treatment of head and neck cancer in the Netherlands.
*Treatment and survival of second primary early-stage lung cancer, following treatment of head and neck cancer in the Netherlands.* Lung Cancer. 2016 Apr;94:54-60 Authors: Louie AV, Damhuis RA, Haasbeek CJ, Warner A, Rodin D, Slotman BJ, Leemans CR, Senan S Abstract OBJECTIVES: The goal of this study was to evaluate treatment patterns and outcomes in early stage (ES) second primary lung cancer (SPLC) after head and neck squamous cell cancer (HNSCC), in the Netherlands. METHODS AND MATERIALS: Details of patients diagnosed between 1997 and 2011 with either an ES primary, or a SPLC a... περισσότερα »
Neck stoma patients: is vital information displayed at the bedside?
*Neck stoma patients: is vital information displayed at the bedside?* Br J Nurs. 2016 Mar 10;25(5):242-7 Authors: Darr A, Siddiq S, Jolly K, Spinou C Abstract Tracheostomies are common procedures in head and neck and critical care practice, with 50% of airway-related deaths attributable to complications such as occlusion or displacement. The National Tracheostomy Safety Project (NTSP) published guidance regarding emergency management of neck stoma patients. A prospective multicentre regional audit of all neck stoma inpatients (ward and intensive care unit (ICU) settings) was condu...περισσότερα »
Effect of vocal fold asymmetries on glottal flow.
*Effect of vocal fold asymmetries on glottal flow.* Laryngoscope. 2016 Mar 12; Authors: Oren L, Khosla S, Gutmark E Abstract OBJECTIVES/HYPOTHESIS: Voice disorders, such as unilateral vocal fold paralysis or paresis, and vocal fold scarring feature structural asymmetries of the vocal folds. Studies on how structural asymmetries affect voice has mostly been limited to computational simulations and experiments on mechanical models. The purpose of the current study is to examine the effects of asymmetries in left-right position, height, and length of the vocal folds on the intraglot... περισσότερα »
Mycobacterium ulcerans disease in the middle belt of Ghana: An eight-year review from six endemic districts.
*Mycobacterium ulcerans disease in the middle belt of Ghana: An eight-year review from six endemic districts.* Int J Mycobacteriol. 2015 Jun;4(2):138-42 Authors: Adu EJ, Ampadu E Abstract BACKGROUND: Mycobacterium ulcerans (MU) produces mycolactone toxin when infected with a plasmid. Toxin is cytotoxic and immunosuppressive, causing extensive destruction of tissues, leading to large ulcers on exposed parts of the body. Spontaneous healing by secondary intention leads to contractures, subluxation of joints, disuse atrophy, distal lymphedema and other complications. The disease is ...περισσότερα »
First results of a novel adjustable-length ossicular reconstruction prosthesis in temporal bones.
*First results of a novel adjustable-length ossicular reconstruction prosthesis in temporal bones.* Laryngoscope. 2016 Mar 12; Authors: Gottlieb PK, Li X, Monfared A, Blevins N, Puria S Abstract OBJECTIVES/HYPOTHESIS: The performance of an ossicular replacement prosthesis (ORP) is influenced by its alignment and appropriate tension between the tympanic membrane and the stapes footplate. A novel ORP with a flexible element that potentially allows for length adjustment in situ is presented and tested for acoustic performance. STUDY DESIGN: Laser Doppler vibrometry in fresh human cad...περισσότερα »
Diverse clinical and laboratory manifestations of bilateral vestibulopathy.
*Diverse clinical and laboratory manifestations of bilateral vestibulopathy.* Laryngoscope. 2016 Mar 12; Authors: Moon M, Chang SO, Kim MB Abstract OBJECTIVES/HYPOTHESIS: To identify the clinical and laboratory characteristics of bilateral vestibulopathy (BVP) on the video head impulse test (vHIT). STUDY DESIGN: Retrospective chart analysis. METHODS: During 23 months, 1,789 patients with dizziness underwent vHIT in our tertiary referral hospital. Of these patients, 65 (3.6%) patients had bilaterally positive catch-up saccades. Based on the caloric test, 15 (group 1) had bilateral... περισσότερα »
Image Guided Radiation Therapy (IGRT) Practice Patterns and IGRT's Impact on Workflow and Treatment Planning: Results From a National Survey of American Society for Radiation Oncology Members.
*Image Guided Radiation Therapy (IGRT) Practice Patterns and IGRT's Impact on Workflow and Treatment Planning: Results From a National Survey of American Society for Radiation Oncology Members.* Int J Radiat Oncol Biol Phys. 2016 Mar 15;94(4):850-7 Authors: Nabavizadeh N, Elliott DA, Chen Y, Kusano AS, Mitin T, Thomas CR, Holland JM Abstract PURPOSE: To survey image guided radiation therapy (IGRT) practice patterns, as well as IGRT's impact on clinical workflow and planning treatment volumes (PTVs). METHODS AND MATERIALS: A sample of 5979 treatment site-specific surveys was e-mai... περισσότερα »
Long-term outcomes after adolescent in-patient treatment due to alcohol intoxication: A control group study
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Cardiopulmonary arrest is the most frequent cause of the unresponsive wakefulness syndrome: a prospective population-based cohort study in Austria
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