Topical brimonidine gel for extended-duration local anesthesia

Abstract

Clinicians have been increasingly using topical anesthetic agents to diminish the pain associated with dermatologic and cosmetic procedures. Among the developed topical anesthetics, lidocaine-based products are the most widely used due to their ample pain relief and minimal side effects.¹ Many local anesthetics and additional techniques have been developed, but the limited duration of local anesthesia is still challenging to the practitioners.

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