Cervical silicone lymphadenopathy
Cervical silicone lymphadenopathy: A patient presented to the department of oral and maxillofacial surgery with a rare case of cervical silicone lymphadenopathy. She had a painless ovoid mass in the left side of her neck and had had cosmetic breast augmentation 10 years before. Radiological imaging and core biopsy examination were consistent with silicone lymphadenopathy.… Continue reading Cervical silicone lymphadenopathy
Radioprotective effects of lycopene and curcumin during local irradiation of parotid glands in Sprague Dawley rats
Radioprotective effects of lycopene and curcumin during local irradiation of parotid glands in Sprague Dawley rats: Radiotherapy effectively treats cancers of the head and neck. We investigated the possible protective effects of lycopene and curcumin on the parotid glands of 40 female Sprague Dawley rats during irradiation. The study followed European Union regulations 86/609/EEC, 2010/63/EU… Continue reading Radioprotective effects of lycopene and curcumin during local irradiation of parotid glands in Sprague Dawley rats
Foregut duplication cyst of the floor of mouth in a neonate. Gastrointestinal cyst, Floor of mouth lesion, Enterocystoma, Enteric duplication cyst,Choristoma
Foregut duplication cyst of the floor of mouth in a neonate: case report: Congenital oral masses may interfere with vital functions such as respiration and deglutition in neonates. We report a congenital heterotopic oral gastrointestinal cyst that caused failure to thrive. A working knowledge of the differential diagnosis and pathophysiology of this can guide the… Continue reading Foregut duplication cyst of the floor of mouth in a neonate. Gastrointestinal cyst, Floor of mouth lesion, Enterocystoma, Enteric duplication cyst,Choristoma
Metabolic and Sensory Influences on Odor Sensitivity in Humans
Metabolic and Sensory Influences on Odor Sensitivity in Humans: Our olfactory sense plays an important role in eating behavior by modulating our food preferences and intake. However, hunger or satiety may also influence how we perceive odors. Albeit speculative, contradictory results found in the past may have resulted from confounding by type of meal that… Continue reading Metabolic and Sensory Influences on Odor Sensitivity in Humans
A Scent of Anxiety: Olfactory Context Conditioning and its Influence on Social Cues
A Scent of Anxiety: Olfactory Context Conditioning and its Influence on Social Cues: Perception and evaluation of objects are highly dependent on surrounding contexts. Threatening contexts enhance processing of faces. Because odors are assumed to deliver strong contextual information, the present study aimed at demonstrating 1) that odors can constitute threat and safety contexts, and… Continue reading A Scent of Anxiety: Olfactory Context Conditioning and its Influence on Social Cues
Changes in Olfactory Sensory Neuron Physiology and Olfactory Perceptual Learning After Odorant Exposure in Adult Mice
Changes in Olfactory Sensory Neuron Physiology and Olfactory Perceptual Learning After Odorant Exposure in Adult Mice: The adult olfactory system undergoes experience-dependent plasticity to adapt to the olfactory environment. This plasticity may be accompanied by perceptual changes, including improved olfactory discrimination. Here, we assessed experience-dependent changes in the perception of a homologous aldehyde pair by… Continue reading Changes in Olfactory Sensory Neuron Physiology and Olfactory Perceptual Learning After Odorant Exposure in Adult Mice
Determinants of Obesity in Adults: The Role of Taste Sensitivity, Food Liking, and Food Neophobia
Determinants of Obesity in Italian Adults: The Role of Taste Sensitivity, Food Liking, and Food Neophobia: Recent evidence has suggested that factors related to sensory perception may explain excess weight. The objective of this study was to consider multiple aspects while investigating the phenomenon of obesity. One goal was to compare taste acuity (taste threshold… Continue reading Determinants of Obesity in Adults: The Role of Taste Sensitivity, Food Liking, and Food Neophobia
Longitudinal Changes in Familiarity, Free and Cued Odor Identification, and Edibility Judgments for Odors in Aging Individuals
Longitudinal Changes in Familiarity, Free and Cued Odor Identification, and Edibility Judgments for Odors in Aging Individuals: This longitudinal study investigated changes in olfaction as assessed by a set of tasks requiring different aspects of semantic information in normal aging individuals. Using 16 odorous items from a standardized olfactory test, the Scandinavian Odor Identification Test,… Continue reading Longitudinal Changes in Familiarity, Free and Cued Odor Identification, and Edibility Judgments for Odors in Aging Individuals
Unravelling the Olfactory Sense: From the Gene to Odor Perception
Unravelling the Olfactory Sense: From the Gene to Odor Perception: Although neglected by science for a long time, the olfactory sense is now the focus of a panoply of studies that bring new insights and raises interesting questions regarding its functioning. The importance in the clarification of this process is of interest for science, but… Continue reading Unravelling the Olfactory Sense: From the Gene to Odor Perception
Collagen barrier membranes adsorb growth factors liberated from autogenous bone chips
Collagen barrier membranes adsorb growth factors liberated from autogenous bone chips: Abstract Objective Collagen membranes serve as barriers to separate bone grafts from soft tissues. Bone grafts harvested with a bone scraper release growth factors activating transforming growth factor-β (TGF-β) signaling in mesenchymal cells. The aim of the present pilot study was to determine whether… Continue reading Collagen barrier membranes adsorb growth factors liberated from autogenous bone chips
Submental Orotracheal Intubation
Submental Orotracheal Intubation: This Surgical Pearl presents a step-by-step description of submental orotracheal intubation to provide surgeons a clear and concise reference when managing the airway in patients with severe facial trauma. This Surgical Pearl presents a step-by-step description of submental orotracheal intubation to provide surgeons a clear and concise reference when managing the airway in patients with severe facial trauma. Severe facial and anterior skull base trauma present particular challenges to the surgeon and anesthesiologist. A variety of methods have b... περισσότερα »
Columellar Incision Scars in Open Rhinoplasty
Columellar Incision Scars in Open Rhinoplasty in Asian Patients: This case series evaluates the incidence and evolution of and risk factors for columellar incision scars in an Asian population undergoing open rhinoplasty. *Importance* An open approach has been adopted for rhinoplasty because of its wide and undistorted exposure. The formation of a columellar incision scar is the main drawback of this approach. *Objective* To evaluate the incidence and evolution of and risk factors for columellar incision scars in an Asian population. *Design, Setting, and Participants* A retros... περισσότερα »
Expression of cell adhesion molecule CD44 in mucoepidermoid carcinoma and its association with the tumor behavior
Expression of cell adhesion molecule CD44 in mucoepidermoid carcinoma and its association with the tumor behavior: Background: The most common malignant salivary gland tumors that affect both adult and children is mucoepidermoid carcinoma. It usually affects both minor and major salivary glands but parotid gland is considering the most common site in which this tumor arises. CD44, a trans-membrane glycoprotein, is an adhesion molecule of cell surface that play a role in the connections between cell-cell and cell-matrix. Many malignant tumors express high levels of CD44, thus, CD44 ma...περισσότερα »
Modification to facilitate the wearing of spectacles by patient after reconstruction with a paramedian forehead pedicled flap
Modification to facilitate the wearing of spectacles by patient after reconstruction with a paramedian forehead pedicled flap: Paramedian forehead pedicled flaps are used for the reconstruction of large nasal and paranasal defects. Traditionally, surgeons divide and inset the pedicle 4-6 weeks after the initial operation.1 For patients, this period can be particularly difficult.
Cervical silicone lymphadenopathy
Cervical silicone lymphadenopathy: A patient presented to the department of oral and maxillofacial surgery with a rare case of cervical silicone lymphadenopathy. She had a painless ovoid mass in the left side of her neck and had had cosmetic breast augmentation 10 years before. Radiological imaging and core biopsy examination were consistent with silicone lymphadenopathy.
Radioprotective effects of lycopene and curcumin during local irradiation of parotid glands in Sprague Dawley rats
Radioprotective effects of lycopene and curcumin during local irradiation of parotid glands in Sprague Dawley rats Radiotherapy effectively treats cancers of the head and neck. We investigated the possible protective effects of lycopene and curcumin on the parotid glands of 40 female Sprague Dawley rats during irradiation. The study followed European Union regulations 86/609/EEC, 2010/63/EU for animal experimentation. The animals were divided into 4 groups: those treated with curcumin and radiation, those treated with lycopene and radiation, those treated with dimethyl sulphoxide (D... περισσότερα »
Foregut duplication cyst of the floor of mouth in a neonate. Gastrointestinal cyst, Floor of mouth lesion, Enterocystoma, Enteric duplication cyst,Choristoma
Foregut duplication cyst of the floor of mouth in a neonate: case report: Congenital oral masses may interfere with vital functions such as respiration and deglutition in neonates. We report a congenital heterotopic oral gastrointestinal cyst that caused failure to thrive. A working knowledge of the differential diagnosis and pathophysiology of this can guide the clinician in its evaluation and management. Abstract Congenital oral masses may interfere with vital functions such as respiration and deglutition in neonates. We report a congenital heterotopic oral gastrointestinal cys... περισσότερα »
Metabolic and Sensory Influences on Odor Sensitivity in Humans
Metabolic and Sensory Influences on Odor Sensitivity in Humans: Our olfactory sense plays an important role in eating behavior by modulating our food preferences and intake. However, hunger or satiety may also influence how we perceive odors. Albeit speculative, contradictory results found in the past may have resulted from confounding by type of meal that participants ate to induce satiety. We aimed to investigate the influence of hunger state on olfactory sensitivity, comparing hunger to satiety using 2 different types of lunch to control for sensory-specific satiety. Odor detect... περισσότερα »
A Scent of Anxiety: Olfactory Context Conditioning and its Influence on Social Cues
A Scent of Anxiety: Olfactory Context Conditioning and its Influence on Social Cues: Perception and evaluation of objects are highly dependent on surrounding contexts. Threatening contexts enhance processing of faces. Because odors are assumed to deliver strong contextual information, the present study aimed at demonstrating 1) that odors can constitute threat and safety contexts, and 2) consequently modulate the processing of faces presented in these contexts. Therefore, previously neutral odors were used as contextual stimuli in a context conditioning paradigm, resulting in an ol...περισσότερα »
Changes in Olfactory Sensory Neuron Physiology and Olfactory Perceptual Learning After Odorant Exposure in Adult Mice
Changes in Olfactory Sensory Neuron Physiology and Olfactory Perceptual Learning After Odorant Exposure in Adult Mice: The adult olfactory system undergoes experience-dependent plasticity to adapt to the olfactory environment. This plasticity may be accompanied by perceptual changes, including improved olfactory discrimination. Here, we assessed experience-dependent changes in the perception of a homologous aldehyde pair by testing mice in a cross-habituation/dishabituation behavioral paradigm before and after a week-long ester-odorant exposure protocol. In a parallel experiment, w... περισσότερα »
Determinants of Obesity in Adults: The Role of Taste Sensitivity, Food Liking, and Food Neophobia
Determinants of Obesity in Italian Adults: The Role of Taste Sensitivity, Food Liking, and Food Neophobia: Recent evidence has suggested that factors related to sensory perception may explain excess weight. The objective of this study was to consider multiple aspects while investigating the phenomenon of obesity. One goal was to compare taste acuity (taste threshold and density of fungiform papillae) in both normal weight and obese subjects. Thresholds for 4 basic tastes and the fat stimulus were investigated. A second research goal was to study the relationship between food neopho... περισσότερα »
Longitudinal Changes in Familiarity, Free and Cued Odor Identification, and Edibility Judgments for Odors in Aging Individuals
Longitudinal Changes in Familiarity, Free and Cued Odor Identification, and Edibility Judgments for Odors in Aging Individuals: This longitudinal study investigated changes in olfaction as assessed by a set of tasks requiring different aspects of semantic information in normal aging individuals. Using 16 odorous items from a standardized olfactory test, the Scandinavian Odor Identification Test, 107 middle aged and older adults were assessed up to three times over a period of 6.5 years, requesting them to rate familiarity and edibility for each odorous item before identifying it wi... περισσότερα »
Unravelling the Olfactory Sense: From the Gene to Odor Perception
Unravelling the Olfactory Sense: From the Gene to Odor Perception: Although neglected by science for a long time, the olfactory sense is now the focus of a panoply of studies that bring new insights and raises interesting questions regarding its functioning. The importance in the clarification of this process is of interest for science, but also motivated by the food and perfume industries boosted by a consumer society with increasingly demands for higher quality standards. In this review, a general overview of the state of art of science regarding the olfactory sense is presented ... περισσότερα »
Collagen barrier membranes adsorb growth factors liberated from autogenous bone chips
Collagen barrier membranes adsorb growth factors liberated from autogenous bone chips: Abstract Objective Collagen membranes serve as barriers to separate bone grafts from soft tissues. Bone grafts harvested with a bone scraper release growth factors activating transforming growth factor-β (TGF-β) signaling in mesenchymal cells. The aim of the present pilot study was to determine whether collagen membranes adsorb molecules from bone-conditioned medium (BCM) with the capacity to provoke the expression of TGF-β target genes *in vitro*. Materials and Methods Collagen membranes were soa...περισσότερα »
Freeze-dried Collagen Scaffolds
Cell Structure, Stiffness and Permeability of Freeze-dried Collagen Scaffolds in Dry and Hydrated States via Acta Biomaterialia Publication date: Available online 28 January 2016 *Source:*Acta Biomaterialia Author(s): M.C. Varley, S. Neelakantan, T.W. Clyne, J. Dean, R.A. Brooks, A.E. Markaki Scaffolds for tissue engineering applications should be highly permeable to support mass transfer requirements while providing a 3-D template for the encapsulated biological cells. High porosity and cell interconnectivity result in highly compliant scaffolds. Overstraining occurs easily with such ... περισσότερα »
The porcine carotid artery
Microstructural quantification of collagen fiber orientations and its integration in constitutive modeling of the porcine carotid artery via Acta Biomaterialia Publication date: Available online 28 January 2016 *Source:*Acta Biomaterialia Author(s): P. Sáez, A. García, E. Peña, T.C. Gasser, M.A. Martínez BackgroundMechanical characteristics of vascular tissue may play a role in different arterial pathologies, which, amongst others, requires robust constitutive descriptions to capture the vessel wall’s anisotropic and non-linear properties. Specifically, the complex 3D network of collage... περισσότερα »
Local propagation speed constrained estimation of the slowness vector from non-planar array observations
Local propagation speed constrained estimation of the slowness vector from non-planar array observations: The estimation of the slowness vector of infrasoundwaves propagating across an array is a critical process leading to the determination of parameters of interest such as the direction of arrival. The sensors of an array are often considered to be located in a horizontal plane. However, due to topography, the altitudes of the sensors are not identical and introduce a bias on the estimate if neglected. However, the unbiased 3D estimation procedure, while suppressing the bias, lea... περισσότερα »
High and Low Dosages of a Component of Milieu Teaching Strategies for Two Preschool-Age Learners With Autism Spectrum Disorder
A Comparison of High and Low Dosages of a Component of Milieu Teaching Strategies for Two Preschool-Age Learners With Autism Spectrum Disorder: Purpose The intersection of treatment intensity and communication intervention is an emerging area of investigation. Milieu teaching (MT) approaches for teaching communication skills to children with autism spectrum disorder (ASD) have a substantial evidence base (see Goldstein, 2002). However, a relatively small percentage (37.8%) of MT studies have fully detailed the parameters that are required to determine treatment intensity (Parker-McG...περισσότερα »
Toddlers' Verb Lexicon Diversity and Grammatical Outcomes
Toddlers' Verb Lexicon Diversity and Grammatical Outcomes: Purpose The goals of this study were to quantify longitudinal expectations for verb lexicon growth and to determine whether verb lexicon measures were better predictors of later grammatical outcomes than noun lexicon measures. Method Longitudinal parent-report measures from the MacArthur-Bates Communicative Development Inventory (Fenson et al., 2007) from ages 21 to 30 months from an archival database were used to model growth in common noun and verb lexicon size for 45 typically developing toddlers. Communicative Developm... περισσότερα »
School-Based Speech-Language Pathologists' Knowledge and Perceptions of Autism Spectrum Disorder and Bullying
School-Based Speech-Language Pathologists' Knowledge and Perceptions of Autism Spectrum Disorder and Bullying: Purpose The purpose of the current investigation was to examine speech-language pathologists' (SLPs') knowledge and perceptions of bullying, with an emphasis on autism spectrum disorder (ASD). Method A 46-item, web-based survey was used to address the purposes of this investigation. Participants were recruited through e-mail and electronic mailing lists for American Speech-Language-Hearing Association (ASHA) special interest divisions 1 (Language, Learning, and Education)...περισσότερα »
Voice Disorder Management Competencies
Voice Disorder Management Competencies: A Survey of School-Based Speech-Language Pathologists in Nebraska: Purpose The purpose of this survey was to determine the self-perceived competence levels in voice disorders of practicing school-based speech-language pathologists (SLPs) and identify correlated variables. Method Participants were 153 master's level, school-based SLPs with a Nebraska teaching certificate and/or licensure who completed a survey, including demographic information and a 25-item voice disorders competency checklist. Results Findings indicated school-based SLPs d... περισσότερα »
Do Live Versus Audio-Recorded Narrative Stimuli Influence Young Children's Narrative Comprehension and Retell Quality?
Do Live Versus Audio-Recorded Narrative Stimuli Influence Young Children's Narrative Comprehension and Retell Quality?: Purpose The primary aim of the present study was to examine whether different ways of presenting narrative stimuli (i.e., live narrative stimuli versus audio-recorded narrative stimuli) influence children's performances on narrative comprehension and oral-retell quality. Method Children in kindergarten (n = 54), second grade (n = 74), and fourth grade ( n = 65) were matched on their performance on a standardized oral-language comprehension task and then were rando... περισσότερα »
Factors Affecting Early Services for Children Who Are Hard of Hearing
Factors Affecting Early Services for Children Who Are Hard of Hearing: Purpose To describe factors affecting early intervention (EI) for children who are hard of hearing, we analyzed (a) service setting(s) and the relationship of setting to families' frequency of participation, and (b) provider preparation, caseload composition, and experience in relation to comfort with skills that support spoken language for children who are deaf and hard of hearing (CDHH). Method Participants included 122 EI professionals who completed an online questionnaire annually and 131 parents who partic... περισσότερα »
Parent Reports of Young Children's Productive Vocabulary
Parent Reports of Young Spanish–English Bilingual Children's Productive Vocabulary: A Development and Validation Study: Purpose This 2-phase study aims to extend research on parent report measures of children's productive vocabulary by investigating the development (n = 38) of the Spanish Vocabulary Extension and validity (n = 194) of the 100-item Spanish and English MacArthur-Bates Communicative Development Inventories Toddler Short Forms and Upward Extension (Fenson et al., 2000, 2007; Jackson-Maldonado, Marchman, & Fernald, 2013) and the Spanish Vocabulary Extension for use with... περισσότερα »
Concurrent Chemoradiation With or Without DC-CIK Immunotherapy in Treating Locally Advanced Esophageal Cancer
Concurrent Chemoradiation With or Without DC-CIK Immunotherapy in Treating Locally Advanced Esophageal Cancer: *Condition*: Esophageal Carcinoma *Interventions*: Other: concurrent chemoradiotherapy plus DC-CIK immunotherapy; Other: Concurrent chemoradiation only *Sponsor*: Capital Medical University ArmsAssigned InterventionsExperimental: concurrent chemoradiotherapy plus DC-CIK immunotherapy patients will receive concurrent chemoradiotherapy plur DC-CIK immunotherapy Other: concurrent chemoradiotherapy plus DC-CIK immunotherapy Radiotherapy:Patients will be conducted CT sim... περισσότερα »
Adoptive Cellular Therapy and Radiation Therapy After Surgery in Treating Patients With Esophageal Cancer
Adoptive Cellular Therapy and Radiation Therapy After Surgery in Treating Patients With Esophageal Cancer: *Condition*: Esophageal Cancer *Interventions*: Radiation: Only radiation therapy; Other: Radiation therapy plus DC-CIK cellular therapy *Sponsor*: Capital Medical University ArmsAssigned InterventionsActive Comparator: Only radiation therapy Radiotherapy:Patients will be conducted CT simulation, and three-dimensional conformal radiation therapy (3DCRT) or Intensity-modulated radiation therapy(IMRT)was performed. 1.8-2.0 Gy/fraction, 5 fractions a week, with a total d...περισσότερα »
Effect of Dexmedetomidine After Thyroidectomy
Effect of Dexmedetomidine After Thyroidectomy The purpose of the present study was to compare the effect of dexmedetomidine which is administered during emergence in adult patients undergoing elective thyroidectomy on smooth emergence form general anesthesia (reducing agitation or coughing, signs of hypertension or tachycardia, or etc.) and postoperative outcome (postoperative bleeding and hospital staying). ConditionInterventionThyroid TumorDrug: Desflurane Drug: Remifentanil Procedure: Thyroidectomy Other: Vital signs Behavioral: Cough reflex Behavioral: Ramsay Sedation Scale O... περισσότερα »
Personalised Postoperative Radiochemotherapy in Patients With Head and Neck Cancer
Personalised Postoperative Radiochemotherapy in Patients With Head and Neck Cancer: *Condition*: Head and Neck Cancer *Intervention*: Radiation: Integration of PET/MRI in radiotherapy *Sponsor*: University Hospital Tuebingen The current trial is evaluating the integration of a pretherapeutical FDG-PET/MRI in the adjuvant radiochemotherapy in patients with head and neck cancer. As a secondary hypothesis the intention is to develop of a multi-parametric decision support system for personalised medicine by integrating functional imaging, γH2AX-analysis and genetic information. ...περισσότερα »
Postoperative Rostral Fluid Shift and Obstructive Sleep Apnea
Postoperative Rostral Fluid Shift and Obstructive Sleep Apnea: *Condition*: Obstructive Sleep Apnea *Intervention*: Other: ApneaLink Plus, BIA Device and a 3-D accelerometer device *Sponsors*: University Health Network, Toronto; Society of Anesthesia and Sleep Medicine Patients with obstructive sleep apnea (OSA) are more likely to experience postoperative complications and impact significantly on healthcare resources. In the surgical population, the type and volume of IV fluid administration may contribute to the worsening of postoperative sleep apnea but the pathophysio... περισσότερα »
Endostar Combined With NVB and DDP Second-line Treatment of Advanced Esophageal Squamous Cell Carcinomas
Endostar Combined With NVB and DDP Second-line Treatment of Advanced Esophageal Squamous Cell Carcinomas: *Condition*: Esophageal Squamous Cell Carcinoma *Interventions*: Drug: NVB; Drug: DDP; Drug: Endostar *Sponsor*: Fudan University ArmsAssigned InterventionsExperimental: Endostar Combined With NVB and DDP Endostar15mg/m2 NVB25 mg/m2 DDP75 mg/m2 Drug: NVB 25mg/m2 ，D1，8 Other Name: Vinorelbine Injection Drug: DDP 75mg/m2 ，D1 or 25mg/m2 D1-3 Other Name: Cisplatin Drug: Endostar 15mg/d，d1-d7 civ Other Name: endo Detailed Description:This study is to explore whether endosta... περισσότερα »
Ciclesonide vs Fluticasone Nasal Sprays in Nasal Poplyposis
Ciclesonide vs Fluticasone Nasal Sprays in Nasal Poplyposis: *Condition*: Chronic Rhinosinustis With Polyps *Interventions*: Drug: Ciclesonide; Drug: Fluticasone *Sponsor*: Tehran University of Medical Sciences ArmsAssigned InterventionsExperimental: CiclesonideDrug: Ciclesonide intranasal ciclesonide spray 200 µg once daily Active Comparator: FluticasoneDrug: Fluticasone fluticasone propionate aqueous nasal spray 200 µg twice a day Detailed Description: The study will be conducted in a tertiary ENT center in Tehran. Endoscopic severity grades for patients will be determined...περισσότερα »
Adenotonsillectomy vs. watchful waiting
Polysomnography results in pediatric patients with mild obstructive sleep apnea: Adenotonsillectomy vs. watchful waiting via International Journal of Pediatric Otorhinolaryngology Publication date: Available online 27 January 2016 *Source:*International Journal of Pediatric Otorhinolaryngology Author(s): Samuel J. Trosman, David J. Eleff, Jyoti Krishna, Samantha Anne ObjectiveThere is a lack of consensus and a paucity of data regarding how to best treat pediatric patients with mild obstructive sleep apnea. The objective of our study was to compare outcomes following adenotonsillectomy v...περισσότερα »
The Association of Congenital Tracheobronchial Stenosis and Cardiovascular Anomalies
The Association of Congenital Tracheobronchial Stenosis and Cardiovascular Anomalies via International Journal of Pediatric Otorhinolaryngology Publication date: Available online 27 January 2016 *Source:*International Journal of Pediatric Otorhinolaryngology Author(s): Yen-Chun Chao, Chun-Chin Peng, Kuo-Sheng Lee, Shan-Miao Lin, Ming-Ren Chen ObjectivesCongenital tracheobronchial stenosis (CTBS) is a rare disorder characterized by the presence of focal or diffuse complete tracheal or bronchial cartilage rings resulting in a fixed lumen narrowing. The aim of this study was to expose the... περισσότερα »
Treatment of Severe Tracheobronchomalacia
: Ten-year experience via International Journal of Pediatric Otorhinolaryngology Publication date: Available online 27 January 2016 *Source:*International Journal of Pediatric Otorhinolaryngology Author(s): Lorraine A. de Trey, Julia Dudley, Hasnaa Ismail-Koch, Andrew Durward, Hannah Bellsham-Revell, Sean Blaney, Ian Hore, Conal B. Austin, Gavin A. Morrison IntroductionPaediatric tracheobronchomalacia is a rare but potentially serious condition. Severe tracheobronchomalacia requires intervention or operation. This is an evaluation of a ten-year experience at an institution.MethodsIn th...περισσότερα »
Otolaryngologic Manifestations of Levamisole-Induced Vasculitis : Necrosis of the ears, malar eminence, and nose are among the most common findings of LIV
Otolaryngologic Manifestations of Levamisole-Induced Vasculitis This case report describes a rare instance of laryngeal involvement in levamisole-induced vasculitis. Levamisole is a synthetic imidazothizole derivative that was introduced in the 1970s for the treatment of rheumatalogic conditions and cancer owing to its immunomodulatory effects.1Although withdrawn from the market in 2000 because of severe adverse reactions,2 *levamisole is commonly found in cocaine. Adverse effects of levamisole include neutropenia, agranulocytosis, and vasculitis. Patients with levamisole-induced ... περισσότερα »
To standardize and improve safety and quality of care for patients undergoing tracheotomy
Improving Outcomes and Promoting Quality in Otolaryngology: Tracheotomy is commonly performed in the pediatric population, with an estimated 4800 tracheotomy procedures performed on patients under the age of 18 years annually in the United States. In particular, infant tracheotomy has previously been identified by Shah et al as one of the largest contributors to morbidity in pediatric otolaryngology. Efforts have begun in the otolaryngology community at local, national, and international levels to standardize and improve safety and quality of care for patients undergoing tracheotomy...περισσότερα »
Slow-Growing Right Mandibular Mass
Slow-Growing Right Mandibular Mass: A young woman had progressive swelling along her right posterior mandible and discomfort with mastication; CT revealed a soft-tissue mass extending into the right retromolar trigone with loss of the intervening fat and soft-tissue planes. What is your diagnosis? [image: First page PDF preview]
Three-Dimensional Pediatric Endoscopy
Three-Dimensional Pediatric Endoscopy: This case series describes the pilot use of 3-dimensional endoscopy to facilitate supraglottoplasty and to assess outcomes in children with laryngomalacia. *Importance* The use of 3-dimensional (3D) endoscopy has been described in the pediatric airway and has been shown to improve visualization of complex airway anatomy. Laryngomalacia is one of the most common airway disorders evaluated in pediatric otolaryngology offices. Whether 3D visualization is superior to standard endoscopy as a means for assessment and surgical management of comple... περισσότερα »
Hypogeusia in Healthy Children
Hypogeusia in Healthy Children: This study examines the incidence of hypogeusia in a group of healthy children as well as correlations with sociodemographic and olfactory findings. *Importance* There are currently no measures of isolated glossopharyngeal taste in healthy children, to our knowledge. *Objective* To define the taste characteristics of an otherwise healthy pediatric population that could serve as a control group for further investigations. *Design, Setting, and Participants* A prospective study of taste and smell was conducted from August 4 to 29, 2014, at a genera... περισσότερα »
Tracheostomy Placement in Children Younger Than 2 Years
Tracheostomy Placement in Children Younger Than 2 Years: This analysis of National Surgical Quality Improvement Program Pediatric data examines factors associated with complications following tracheostomy placement in patients younger than 2 years. *Importance* Analysis of the American College of Surgeons National Surgical Quality Improvement Program (NSQIP) Pediatric demonstrated that the highest contribution to composite morbidity in otolaryngology is seen in children younger than 2 years undergoing tracheostomy. *Objective* To determine predictive factors for complications fo...περισσότερα »
Knowledge and risk perception of oral cavity and oropharyngeal cancer
Knowledge and risk perception of oral cavity and oropharyngeal cancer among non-medical university students: To assess non-medical university students' knowledge and perceived risk of developing oral cavity and oropharyngeal cancer. Background To assess non-medical university students' knowledge and perceived risk of developing oral cavity and oropharyngeal cancer. Methods A cross-sectional survey was conducted among non-medical students of a private Midwestern university in the United States in May 2012. Questionnaire assessed demographic information and contained 21 previou... περισσότερα »
Recurrence of Juvenile Nasopharyngeal Angiofibroma
Time Trends in Recurrence of Juvenile Nasopharyngeal Angiofibroma: Experience of past 4 decades via American Journal of Otolaryngology Publication date: Available online 28 January 2016 *Source:*American Journal of Otolaryngology Author(s): Mishra Anupam, Mishra Subhash Chandra BackgroundAn analysis of time distribution of juvenile nasopharyngeal angiofibroma (JNA) from last 4 decades is presented.MethodsSixty recurrences were analysed as per actuarial survival. SPSS software was used to generate Kaplan Myer (KM) curves and time distributions were compared by Logrank, Breslow and Taron... περισσότερα »
Chronic sclerosing sialadenitis,Sclerosing Sialadenitis, Parotid gland, Küttner's tumor.
Uncommon situation and presentation of chronic sclerosing sialadenitis Abstract Chronic sclerosing sialadenitis of the parotid gland is a very uncommon chronic inflammatory salivary gland disease. Clinically, it presents as a slow-growing painful. Histologically, it showed a chronic inflammation and fibrosis. This case report highlights the clinical, radiological and histological aspects of this disease. We report unusual case of chronic sclerosing sialadenitis of the parotid in a 12-year-old man. CT detected a mass of tissue density in the right parotid. The evolution was marked ... περισσότερα »
Allergic Rhinitis : Evaluation the of Intranasal Infiltrated Botulinum Toxin-A
Evaluation the of Intranasal Infiltrated Botulinum Toxin-A on a Model of Allergic Rhinitis in Rabbits: An Experimental Study: Allergic Rhinitis (AR) effects 20-40% of the global population and its prevalance increases. Medical treatment and immunotherapy could be used in AR management. But they are not definitive solution. Medical treatment must be used a long time and has side effects. Immunotherapy can not be applied to every patient and it also takes a long time. The aim of this study is to evaluate symptomatic and histopathological effects of intranasal infiltrated Botulinum Tox... περισσότερα »
DEFB1 polymorphisms and susceptibility to recurrent tonsillitis
Article in Press *DEFB1* polymorphisms and susceptibility to recurrent tonsillitis in Italian children Luisa Zupin[image: correspondence][image: email] , Vania Polesello , Domenico Leonardo Grasso , Sergio Crovella , Ludovica Segat DOI: http://dx.doi.org/10.1016/j.ijporl.2016.01.025 - AbstractIntroduction the tonsils are secondary lymphoid organs fundamental for immune system response against pathogens within the oral cavity. Tonsillitis refers to inflammation of the pharyngeal tonsils that may include the adenoids and the lingual tonsils and that can be acute, recurrent, and... περισσότερα »
Comparison of clinical and radiographic status of platform-switched implants placed in patients with and without type 2 diabetes mellitus: a 24-month follow-up longitudinal study
Abstract Objective The purpose of the present 24-month follow-up longitudinal study was to compare the clinical and radiographic status of platform-switched implants placed in patients with and without type 2 diabetes mellitus (T2DM). Material and methods In total, 45 male non-smokers were included. In Group-1, there were 23 patients with T2DM, and patients in Group-2 comprised of 22 self-reported non-diabetic controls. Under local anesthesia, platform-switched implants were placed in the mandible. Peri-implant bleeding on probing (BOP), probing depth (PD), marginal bone loss (MB...περισσότερα »
Foregut duplication cyst of the floor of mouth in a neonate: case report
Congenital oral masses may interfere with vital functions such as respiration and deglutition in neonates. We report a congenital heterotopic oral gastrointestinal cyst that caused failure to thrive. A working knowledge of the differential diagnosis and pathophysiology of this can guide the clinician in its evaluation and management. from #ΓναθοΧειρουργική via xlomafota13 on Inoreader http://ift.tt/1OTz1zo via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
Radioprotective effects of lycopene and curcumin during local irradiation of parotid glands in Sprague Dawley rats
Radiotherapy effectively treats cancers of the head and neck. We investigated the possible protective effects of lycopene and curcumin on the parotid glands of 40 female Sprague Dawley rats during irradiation. The study followed European Union regulations 86/609/EEC, 2010/63/EU for animal experimentation. The animals were divided into 4 groups: those treated with curcumin and radiation, those treated with lycopene and radiation, those treated with dimethyl sulphoxide (DMSO) and radiation, and those treated with radiation alone. from #ΓναθοΧειρουργική via xlomafota13 on Inoreader h... περισσότερα »
Cervical silicone lymphadenopathy
A patient presented to the department of oral and maxillofacial surgery with a rare case of cervical silicone lymphadenopathy. She had a painless ovoid mass in the left side of her neck and had had cosmetic breast augmentation 10 years before. Radiological imaging and core biopsy examination were consistent with silicone lymphadenopathy. from #ΓναθοΧειρουργική via xlomafota13 on Inoreader http://ift.tt/1nC45uR via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
The Inflatable Thymus Herniation of the Normal Mediastinal Thymus
Article in Press : A Case Report and Review of the Literature Marijn Stuut1[image: correspondence][image: email] , Gusta van Zwieten1 , Jos M. Straetmans , Martin Lacko , Constance T.R.M. Stumpel 1^co-first authorship DOI: http://dx.doi.org/10.1016/j.ijporl.2016.01.019 - Abstract Anterior neck masses in young children can be a diagnostic challenge for otolaryngologists and radiologists. We present a rare case of herniation of normal mediastinal thymus in a four-year-old girl. Additional medical features as an inguinal hernia and trochlear nerve paresis raised the question whe...περισσότερα »
Nasal fluid secretory immunoglobulin A levels in children with allergic rhinitis
Nasal fluid secretory immunoglobulin A levels in children with allergic rhinitis: There is growing knowledge about the immunoregulatory and possibly preventative roles of immunoglobulin A (IgA) in allergic diseases. This study aimed to investigate secretory immunoglobulin A (SIgA) levels in the nasal fluid of children who were either being treated for their allergic rhinitis (AR) with intranasal mometasone furoate or were not receiving treatment. AbstractObjectives There is growing knowledge about the immunoregulatory and possibly preventative roles of immunoglobulin A (IgA) in a...περισσότερα »
Late infantile neuronal ceroid lipofuscinosis (CLN2 disease) is a uniformly fatal lysosomal storage disease resulting from mutations in the CLN2 gene
Brain Region-Specific Degeneration with Disease Progression in Late Infantile Neuronal Ceroid Lipofuscinosis (CLN2 Disease) [PEDIATRICS] by Dyke, J. P., Sondhi, D., Voss, H. U., Yohay, K., Hollmann, C., Mancenido, D., Kaminsky, S. M., Heier, L. A., Rudser, K. D., Kosofsky, B., Casey, B. J., Crystal, R. G., Ballon, D. via Neuroradiology BACKGROUND AND PURPOSE:Late infantile neuronal ceroid lipofuscinosis (CLN2 disease) is a uniformly fatal lysosomal storage disease resulting from mutations in the *CLN2* gene. Our hypothesis was that regional analysis of cortical brain degeneration may ... περισσότερα »
Short ventilation times are associated with a lower pneumonia rate and more favorable clinical outcome
Clinical Impact of Ventilation Duration in Patients with Stroke Undergoing Interventional Treatment under General Anesthesia: The Shorter the Better? [ADULT BRAIN]: BACKGROUND AND PURPOSE: Whether general anesthesia for neurothrombectomy in patients with ischemic stroke has a negative impact on clinical outcome is currently under discussion. We investigated the impact of early extubation and ventilation duration in a cohort that underwent thrombectomy under general anesthesia. MATERIALS AND METHODS: We analyzed 103 consecutive patients from a prospective stroke registry. They met t... περισσότερα »
Adjuvant immunotherapy may improve survival in patients with metastatic pediatric sarcoma.
ADJUVANT IMMUNOTHERAPY TO IMPROVE OUTCOME IN HIGH RISK PEDIATRIC SARCOMAS: PURPOSE: Patients with metastatic or relapsed pediatric sarcomas receive cytotoxic regimens that induce high remission rates associated with profound lymphocyte depletion, but ultimately few survive long-term. We administered adjuvant immunotherapy to patients with metastatic and recurrent pediatric sarcomas in an effort to improve outcomes. EXPERIMENTAL DESIGN: Mononuclear cells were collected via apheresis and tumor lysate was acquired via percutaneous biopsy at enrollment. Participants received standard a... περισσότερα »
Angiogenesis- or hypoxia-related proteins : Plasma Circulating Proteins and Bevacizumab
Plasma Circulating Proteins and Bevacizumab: *Purpose:* We examined whether pretreatment levels of angiogenesis- or hypoxia-related proteins and their changes after one cycle of first-line bevacizumab-based therapy were associated with response, PFS, or OS in patients with metastatic breast cancer. *Experimental Design:* We included 181 patients enrolled in the phase II ATX trial evaluating first-line paclitaxel and bevacizumab without or with capecitabine (NTR1348). Plasma samples were analyzed for VEGF-A, soluble VEGFR2 (sVEGFR2), angiopoietin 2 (ANG2), soluble TIE2 (sTIE2), IL6,...περισσότερα »
Infected concha bullosa mimicking a malignant lesion
on 18F-FDG PET/CT via Revista Española de Medicina Nuclear e Imagen Molecular Publication date: Available online 28 January 2016 [image: A 77-year-old man patient with a history of lower extremity soft tissue sarcoma ...] *Source:*Revista Española de Medicina Nuclear e Imagen Molecular Author(s): S. Gungor, S. Asa, A. Özgür, M. Aras, F. Dede
Novel Clinical Scale for Evaluating Pre-Operative Risk of Cerebral Herniation from Traumatic Epidural Hematoma
Journal of Neurotrauma , Vol. 0, No. 0. from Neurology via xlomafota13 on Inoreader http://ift.tt/1UuzJV7 via IFTTT
The Effect of Cranioplasty on Cerebral Hemodynamics as Measured by Perfusion Computed Tomography and Doppler Ultrasonography
Journal of Neurotrauma , Vol. 0, No. 0. from Neurology via xlomafota13 on Inoreader http://ift.tt/1PE9PKi via IFTTT
Core Outcomes and Common Data Elements in Chronic Subdural Hematoma: A Systematic Review of the Literature Focusing on Baseline and Peri-Operative Care Data Elements
Journal of Neurotrauma , Vol. 0, No. 0. from Neurology via xlomafota13 on Inoreader http://ift.tt/1SNj6WU via IFTTT
Leukemia Inhibitory Factor Haplodeficiency Desynchronizes Glial Reactivity and Exacerbates Damage and Functional Deficits after a Concussive Brain Injury
Journal of Neurotrauma , Vol. 0, No. 0. from Neurology via xlomafota13 on Inoreader http://ift.tt/1OTErdB via IFTTT
Autophagy Modulation by Lanthionine Ketimine Ethyl Ester Improves Long-Term Outcome after Central Fluid Percussion Injury in the Mouse
Journal of Neurotrauma , Vol. 0, No. 0. from Neurology via xlomafota13 on Inoreader http://ift.tt/1PmjpWl via IFTTT
Longitudinal Evaluation of Residual Cortical and Subcortical Motor Evoked Potentials in Spinal Cord Injured Rats
Journal of Neurotrauma , Vol. 0, No. 0. from Neurology via xlomafota13 on Inoreader http://ift.tt/1SNj4OT via IFTTT
A Multidimensional Rasch Analysis of the Functional Independence Measure based on the National Institute on Disability, Independent Living, and Rehabilitation Research Traumatic Brain Injury Model Systems National Database
Journal of Neurotrauma , Vol. 0, No. 0. from Neurology via xlomafota13 on Inoreader http://ift.tt/1PE9PtG via IFTTT
FDG-PET/CT of non-small cell lung carcinoma under neo-adjuvant chemotherapy: background based adaptive volume metrics outperform TLG and MTV in predicting histopathological response
Assessment of tumor response after chemotherapy using FDG PET metrics is gaining acceptance. Several studies have suggested that the parameters metabolically active tumor volume (MTV) or total lesion glycolysis (TLG) are superior for measuring the tumor burden compared to the maximum standardized uptake value (SUVmax). However, the measurement of MTV and TLG is still controversial;… Continue reading FDG-PET/CT of non-small cell lung carcinoma under neo-adjuvant chemotherapy: background based adaptive volume metrics outperform TLG and MTV in predicting histopathological response
Voriconazole-induced skeletal fluorosis in an allogenic hematopoietic stem cell transplant recipient
from #ORL-AlexandrosSfakianakis via simeraentaxei on Inoreader http://ift.tt/1nR6Jg6 via IFTTT
Synthesis of Cu 2 O nanowire mesocrystals using PTCDA as a modifier and their superior peroxidase-like activity
Abstract Cu2O nanowire mesocrystals (NWMCs), which possess well-defined octahedral morphology and high-porosity architecture with anisotropic interpenetrating nanowires, have attracted considerable attention owing to their superior physical and chemical properties. However, the current synthetic approach for Cu2O NWMCs using graphene oxide as modifier leads to uncontrollable products and low productivity (~30 %), which largely hinder their… Continue reading Synthesis of Cu 2 O nanowire mesocrystals using PTCDA as a modifier and their superior peroxidase-like activity
End-Stage Liver Disease Is a Strong Predictor of Early Mortality in Cryptococcosis
Background. Cryptococcosis in the setting of end-stage liver disease (ESLD) has been associated with high mortality. We sought to compare the outcome of cryptococcal disease in patients with ESLD to that of human immunodeficiency virus (HIV)-positive patients and to those patients without HIV or ESLD. Methods. We assembled a retrospective cohort of 232 consecutive cases… Continue reading End-Stage Liver Disease Is a Strong Predictor of Early Mortality in Cryptococcosis
Pharmacokinetic analysis of 11C-PBR28 in the rat model of herpes encephalitis (HSE): comparison with (R)-11C-PK11195
11C-PBR28 is a second generation TSPO tracer with supposedly superior characteristics than the most commonly used tracer for neuroinflammation, (R)-11C-PK11195. Despite its use in clinical research, no studies on the imaging properties and pharmacokinetic analysis of 11C-PBR28 in rodent models of neuroinflammation have been published yet. Therefore, this study aims to evaluate 11C-PBR28 as a… Continue reading Pharmacokinetic analysis of 11C-PBR28 in the rat model of herpes encephalitis (HSE): comparison with (R)-11C-PK11195
Enhanced hydrothermal stability of ZSM-5 formed from nanocrystalline seeds for naphtha catalytic cracking
Abstract We successfully synthesized hydrothermally stable ZSM-5 with crystalline nano seeds. We employed a template-free method using ZSM-5 crystalline nano seeds and sodium silicate as a silica source. The prepared ZSM-5 exhibited uniform crystal size and relative crystallinity greater than 100 %. The size of the crystalline nano seed in the scale of 100 nm… Continue reading Enhanced hydrothermal stability of ZSM-5 formed from nanocrystalline seeds for naphtha catalytic cracking
High diagnostic value of FDG-PET/CT in endometrial cancer: Systematic review and meta-analysis of the literature.
Aim: To evaluate the diagnostic performance of fluorodeoxyglucose positron emission tomography/computed tomography (FDG-PET/CT) for the preoperative assessment of lymph node metastases (LNM) in endometrial cancer patients and for the assessment of endometrial cancer recurrence (ECR) after primary surgical treatment. Methods: A comprehensive search was performed on Pubmed/MEDLINE databases for studies reporting the diagnostic performance of… Continue reading High diagnostic value of FDG-PET/CT in endometrial cancer: Systematic review and meta-analysis of the literature.
Surgical robots good for cancer operations, but drawbacks remain – Maryland Daily Record (subscription)
Maryland Daily Record (subscription) Surgical robots good for cancer operations, but drawbacks remain Maryland Daily Record (subscription) Treating tongue and tonsil cancer with surgery used to be so invasive, it was hardly ever done. The procedure often involved a large incision in the neck, a tracheotomy to enable breathing, and a long and difficult recovery… Continue reading Surgical robots good for cancer operations, but drawbacks remain – Maryland Daily Record (subscription)
Leitlinienkonforme psychiatrisch-psychotherapeutische Behandlung für Patienten mit Schizophrenie
Zusammenfassung Hintergrund Obwohl sowohl nationale und als auch internationale Leitlinien sowie der Gemeinsame Bundesausschuss die kognitive Verhaltenstherapie für Patienten mit Schizophrenie in allen Erkrankungsphasen empfehlen, ist diese Empfehlung stationär und ambulant bisher nur rudimentär umgesetzt. Ziel der Arbeit Das Ziel der vorliegenden Arbeit besteht darin, aus bestehenden Primärstudien und Metaanalysen den Personalbedarf einer leitliniengerechten, stationären… Continue reading Leitlinienkonforme psychiatrisch-psychotherapeutische Behandlung für Patienten mit Schizophrenie
Electrowetting on a multi-walled carbon nanotube membrane with different droplet sizes in an electric field
Abstract An electric field was applied across a deionized water droplet placed on a multi-walled carbon nanotube (MWCNT) membrane. Droplets of different size were tested by varying the voltage applied from 3 to 25 V during the electrowetting process. After electrowetting, it was observed that the topography of the membrane deformed from vertical alignment to… Continue reading Electrowetting on a multi-walled carbon nanotube membrane with different droplet sizes in an electric field
Regulation of prostate cancer progression by the tumor microenvironment
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 1 ώρα
• Both innate and adaptive immune cells contribute to prostate cancer progression• Non-immune and immune stroma regulate each other and their effect on tumor cells• Stromal cells exert their influence via direct cell-to-cell contact, soluble factors and extracellular vesicles from #ORL-AlexandrosSfakianakis via simeraentaxei on Inoreader http://ift.tt/1Ke7QQQ via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete […]
Ocular involvement in an HIV-infected patient: not always an infectious disease. An interesting case without apparent cause
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 1 ώρα
We describe the case of a young girl with HIV infection vertically transmitted who presented a long-lasting ocular involvement characterized by several relapses and remissions. Good viral and immunological status made infective or neoplastic facts unlike; diagnosis was really challenging and finally spontaneous remission was observed after several months. Clinical and histopathological findings made idiopathic […]
New study using cryo-electron microscopy shows how potential drugs could inhibit cancer
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 1 ώρα
from #ORL-AlexandrosSfakianakis via simeraentaxei on Inoreader http://ift.tt/1nrqcDA via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
Previously published midazolam–alfentanil response surface model cannot predict patient response well in gastro intestinal endoscopy sedation
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 1 ώρα
A response surface model is a mathematical model used to predict multiple-drug pharmacodynamic interactions. With the use of a previously published volunteer model, we tested the accuracy of the midazolam–alfentanil response surface model during gastrointestinal endoscopy. from #ORL-AlexandrosSfakianakis via simeraentaxei on Inoreader http://ift.tt/1SN98oE via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & […]
The reverse abdominal reduction and the “waistcoating” procedure for the correction of the fixated pfannenstiel incision
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 1 ώρα
The principles of a standard abdominal reduction are well understood and as a technique it has been used for many years. There are occasions, however, where, for example, an abdominal reduction has already been carried out but continued weight loss has led to skin redundancy on the upper abdomen or in cases where the upper […]
Fascicle length does increase in response to longitudinal resistance training and in a contraction-mode specific manner
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 1 ώρα
No description available from #ORL-AlexandrosSfakianakis via simeraentaxei on Inoreader http://ift.tt/1nrpyG1 via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
Food allergies can persist after myeloablative hematopoietic stem cell transplantation in dedicator of cytokinesis 8–deficient patients
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 1 ώρα
Dedicator of cytokinesis 8 (DOCK8) deficiency is a highly morbid combined immunodeficiency that features recurrent sinopulmonary infections, viral skin infections, and severe food allergies.1,2 Hematopoietic stem cell transplantation (HSCT) cures infection susceptibility in patients with DOCK8 deficiency.3-7 Whether HSCT also cures food allergy has not been systematically examined in human subjects.8 To gain insight into […]
Technical note: Developing the use of Structure-from-Motion in mass grave documentation
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 1 ώρα
The scientific excavation of mass-graves, which draws on techniques from both forensic anthropology and traditional field archaeology, has become an essential component of forensic work [1–3]. In the past twenty years, the number of mass-grave excavations has exceeded several dozen; this number is unlikely to decrease in the forthcoming years, as conflict and war have […]
Food allergies can persist after myeloablative hematopoietic stem cell transplantation in dedicator of cytokinesis 8–deficient patients
sfakianakismedicsστοORL ALLERGY AESTHETICS ANATOMY Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Dedicator of cytokinesis 8 (DOCK8) deficiency is a highly morbid combined immunodeficiency that features recurrent sinopulmonary infections, viral skin infections, and severe food allergies.1,2 Hematopoietic stem cell transplantation (HSCT) cures infection susceptibility in patients with DOCK8 deficiency.3-7 Whether HSCT also cures food allergy has not been systematically examined in human subjects.8 To gain insight into […]
Differential effects of suppressors on hazardous sound pressure levels generated by AR-15 rifles: Considerations for recreational shooters, law enforcement, and the military
10.3109/14992027.2015.1122241<br>Edward Lobarinas from #Audiology via ola Kala on Inoreader http://ift.tt/1nC2eGi via IFTTT
Effects of low speed wind on the recognition/identification and pass-through communication tasks of auditory situation awareness afforded by military hearing protection/enhancement devices and tactical communication and protective systems
10.3109/14992027.2015.1129073<br>Kichol Lee from #Audiology via ola Kala on Inoreader http://ift.tt/1nC2d55 via IFTTT
Differential effects of suppressors on hazardous sound pressure levels generated by AR-15 rifles: Considerations for recreational shooters, law enforcement, and the military
10.3109/14992027.2015.1122241<br>Edward Lobarinas from #Audiology via xlomafota13 on Inoreader http://ift.tt/1nC2eGi via IFTTT
Effects of low speed wind on the recognition/identification and pass-through communication tasks of auditory situation awareness afforded by military hearing protection/enhancement devices and tactical communication and protective systems
10.3109/14992027.2015.1129073<br>Kichol Lee from #Audiology via xlomafota13 on Inoreader http://ift.tt/1nC2d55 via IFTTT
Differential effects of suppressors on hazardous sound pressure levels generated by AR-15 rifles: Considerations for recreational shooters, law enforcement, and the military
10.3109/14992027.2015.1122241<br>Edward Lobarinas from #Audiology via ola Kala on Inoreader http://ift.tt/1nC2eGi via IFTTT
Effects of low speed wind on the recognition/identification and pass-through communication tasks of auditory situation awareness afforded by military hearing protection/enhancement devices and tactical communication and protective systems
10.3109/14992027.2015.1129073<br>Kichol Lee from #Audiology via ola Kala on Inoreader http://ift.tt/1nC2d55 via IFTTT
Differential effects of suppressors on hazardous sound pressure levels generated by AR-15 rifles: Considerations for recreational shooters, law enforcement, and the military
10.3109/14992027.2015.1122241<br>Edward Lobarinas from #Audiology via ola Kala on Inoreader http://ift.tt/1nBWkF9 via IFTTT
Effects of low speed wind on the recognition/identification and pass-through communication tasks of auditory situation awareness afforded by military hearing protection/enhancement devices and tactical communication and protective systems
10.3109/14992027.2015.1129073<br>Kichol Lee from #Audiology via ola Kala on Inoreader http://ift.tt/1WQHiqG via IFTTT
Differential effects of suppressors on hazardous sound pressure levels generated by AR-15 rifles: Considerations for recreational shooters, law enforcement, and the military
10.3109/14992027.2015.1122241<br>Edward Lobarinas from #Audiology via ola Kala on Inoreader http://ift.tt/1nBWkF9 via IFTTT
Effects of low speed wind on the recognition/identification and pass-through communication tasks of auditory situation awareness afforded by military hearing protection/enhancement devices and tactical communication and protective systems
10.3109/14992027.2015.1129073<br>Kichol Lee from #Audiology via ola Kala on Inoreader http://ift.tt/1WQHiqG via IFTTT
Does the Hippocampus Map Out the Future?
Publication date: Available online 28 January 2016 *Source:*Trends in Cognitive Sciences Author(s): Daniel Bendor, Hugo J. Spiers Decades of research have established two central roles of the hippocampus – memory consolidation and spatial navigation. Recently, a third function of the hippocampus has been proposed: simulating future events. However, claims that the neural patterns underlying simulation occur without prior experience have come under fire in light of newly published data. from Neurology via xlomafota13 on Inoreader http://ift.tt/1KejUkW via IFTTT
Teilleistungsstörungen/MCD und ADHS im Erwachsenenalter
Zusammenfassung Das Aufmerksamkeitsdefizit-Hyperaktivitäts-Syndrom (ADHS) ist nicht nur im Kindesalter, sondern auch im Erwachsenenalter ein häufiges Problem. Allerdings sind trotz umfangreicher Forschung grundlegende Fragen der diagnostischen Abgrenzung weiter ungeklärt. ADHS-Patienten leiden nicht nur unter Störungen der Aufmerksamkeit oder Hyperaktivität, die zudem nicht einmal obligat sind, sondern auch unter einem breiten Spektrum an weiteren Symptomen, wie Dyspraxien, Problemen mit der Reizdiskrimination, Dysgrammatismus, Legasthenie, motorischer Ungeschicklichkeit u. ä. Des ... περισσότερα »
Hirntod und Konsequenzen
from Neurology via xlomafota13 on Inoreader http://ift.tt/1Kej7AH via IFTTT
Bauliche Modernisierungen in psychiatrischen Kliniken beeinflussen Zwangsmaßnahmen
Zusammenfassung Hintergrund Zwangsmaßnahmen werden in psychiatrischen Kliniken häufig als letztes Mittel gegen eigen- bzw. fremdgefährdendes Verhalten eingesetzt, mit negativen psychischen und somatischen Folgen für die Betroffenen. Ziel In einer naturalistischen Beobachtungsstudie untersuchten wir, ob das strukturelle Milieu einer psychiatrischen Klinik, das durch den Umzug in einen architektonisch positiver gestalteten Neubau verbessert wurde, die Anwendung von Zwangsmaßnahmen beeinflusst. Material und Methoden Die Häufigkeit und Dauer von Zwangsmaßnahmen (Fixierungen, Zwangsm... περισσότερα »
Leitlinienkonforme psychiatrisch-psychotherapeutische Behandlung für Patienten mit Schizophrenie
Zusammenfassung Hintergrund Obwohl sowohl nationale und als auch internationale Leitlinien sowie der Gemeinsame Bundesausschuss die kognitive Verhaltenstherapie für Patienten mit Schizophrenie in allen Erkrankungsphasen empfehlen, ist diese Empfehlung stationär und ambulant bisher nur rudimentär umgesetzt. Ziel der Arbeit Das Ziel der vorliegenden Arbeit besteht darin, aus bestehenden Primärstudien und Metaanalysen den Personalbedarf einer leitliniengerechten, stationären psychiatrisch-psychotherapeutischen Schizophreniebehandlung zu berechnen und diesen mit den in der Psychiatri... περισσότερα »
Psychiatrie als praktische Wissenschaft
Zusammenfassung Vor dem Hintergrund historischer und aktueller Kritik am Fach Psychiatrie und Psychotherapie als medizinische Fachdisziplin erfolgt eine Auseinandersetzung mit den medizintheoretischen Überlegungen des Arztes und Philosophen Wolfgang Wieland. In dessen Beiträgen wird die Medizin als praktische Wissenschaft angesehen, deren Ziel die Begründung vernünftigen Handelns ist. Im Mittelpunkt dieses Modells steht die Diagnose, mit deren Hilfe der einzelne Fall unter allgemeine Gesetzmäßigkeiten subsumiert wird. Aus dieser Zuordnung lassen sich dann die wesentlichen Handlungs... περισσότερα »
Complete resection of contrast-enhancing tumor volume is associated with improved survival in recurrent glioblastoma--results from the DIRECTOR trial
Background The role of reoperation for recurrent glioblastoma (GBM) remains unclear. Prospective studies are lacking. Here, we studied the association of clinical outcome with extent of resection upon surgery for recurrent GBM in the patient cohort of DIRECTOR, a prospective randomized multicenter trial comparing 2 dose-intensified temozolomide regimens at recurrence of GBM. Methods We analyzed prospectively collected clinical and imaging data from the DIRECTOR cohort (*N* = 105). Volumetric analysis was performed on gadolinium contrast-enhanced MRI as well as fluid attenuated i...περισσότερα »
Foregut duplication cyst of the floor of mouth in a neonate: case report
Congenital oral masses may interfere with vital functions such as respiration and deglutition in neonates. We report a congenital heterotopic oral gastrointestinal cyst that caused failure to thrive. A working knowledge of the differential diagnosis and pathophysiology of this can guide the clinician in its evaluation and management. from OroFacial Medicine via ola Kala on Inoreader http://ift.tt/1OTz1zo via IFTTT
Radioprotective effects of lycopene and curcumin during local irradiation of parotid glands in Sprague Dawley rats
Radiotherapy effectively treats cancers of the head and neck. We investigated the possible protective effects of lycopene and curcumin on the parotid glands of 40 female Sprague Dawley rats during irradiation. The study followed European Union regulations 86/609/EEC, 2010/63/EU for animal experimentation. The animals were divided into 4 groups: those treated with curcumin and radiation, those treated with lycopene and radiation, those treated with dimethyl sulphoxide (DMSO) and radiation, and those treated with radiation alone. from OroFacial Medicine via ola Kala on Inoreader htt... περισσότερα »
Cervical silicone lymphadenopathy
A patient presented to the department of oral and maxillofacial surgery with a rare case of cervical silicone lymphadenopathy. She had a painless ovoid mass in the left side of her neck and had had cosmetic breast augmentation 10 years before. Radiological imaging and core biopsy examination were consistent with silicone lymphadenopathy. from OroFacial Medicine via ola Kala on Inoreader http://ift.tt/1nC45uR via IFTTT
Modification to facilitate the wearing of spectacles by patient after reconstruction with a paramedian forehead pedicled flap
Paramedian forehead pedicled flaps are used for the reconstruction of large nasal and paranasal defects. Traditionally, surgeons divide and inset the pedicle 4-6 weeks after the initial operation.1 For patients, this period can be particularly difficult. from OroFacial Medicine via ola Kala on Inoreader http://ift.tt/1OTz1z7 via IFTTT
A Comprehensive Multistate Model Analyzing Associations of Various Risk Factors With the Course of Breast Cancer in a Population-Based Cohort of Breast Cancer Cases
We employed a semi-Markov multistate model for the simultaneous analysis of various endpoints describing the course of breast cancer. Results were compared with those from standard analyses using a Cox proportional hazards model. We included 3,012 patients with invasive breast cancer newly diagnosed between 2001 and 2005 who were recruited in Germany for a population-based study, the Mamma Carcinoma Risk Factor Investigation (MARIE Study), and prospectively followed up until the end of 2009. Locoregional recurrence and distant metastasis were included as intermediate states, and d...περισσότερα »
Plasma Biomarkers of Inflammation, the Kynurenine Pathway, and Risks of All-Cause, Cancer, and Cardiovascular Disease Mortality: The Hordaland Health Study
We aimed to evaluate 10 biomarkers related to inflammation and the kynurenine pathway, including neopterin, kynurenine:tryptophan ratio, C-reactive protein, tryptophan, and 6 kynurenines, as potential predictors of all-cause and cause-specific mortality in a general population sample. The study cohort was participants involved in a community-based Norwegian study, the Hordaland Health Study (HUSK). We used Cox proportional hazards models to assess associations of the biomarkers with all-cause mortality and competing-risk models for cause-specific mortality. Of the 7,015 participan...περισσότερα »
The Johns Hopkins Bloomberg School of Public Health: A Brief History of a Century of Epidemiologic Discovery
During its first century, the Johns Hopkins University Bloomberg School of Public Health has been home to several faculty members who have played leading roles in defining and expanding the field and science of epidemiology. They have done so by training leaders in the field, creating new methods and applications, and making relevant discoveries in the worlds of infectious and chronic diseases. These methodologic innovations and discoveries underlie many of today's major health policies and practices. from #Oncology via alexandrossfakianakis on Inoreader http://ift.tt/1KJcKjD via ... περισσότερα »
[Surgical treatment of intracranial aneurysms via the pterional keyhole approach].
Related Articles *[Surgical treatment of intracranial aneurysms via the pterional keyhole approach].* Zhonghua Yi Xue Za Zhi. 2015 Oct;95(39):3209-12 Authors: Lan Q, Zhu Q, Chen A, Yu J, Liu S Abstract OBJECTIVE: Modify the pterional approach for intracranial aneurysms clipping with minimally invasive concept to reduce the risk of iatrogenic surgical trauma. METHODS: A 4.0 cm skin incision was made along the temporal hairline and centered on the pterion, temporal muscle was incised along the sylvian fissure.A bone flap with 2.0 to 2.5 cm in diameter was milled after a bone hole ... περισσότερα »
Herpes Zoster and Post-herpetic Neuralgia
Abstract Herpes zoster (HZ), which is commonly referred to as shingles, is a syndrome of pain and skin rash that is caused by reactivation of varicella zoster virus (VZV). After primary varicella infection (chicken pox), the virus goes into latency in the spinal cord ganglia. The virus is reactivated when immunity to VZV declines as… Continue reading Herpes Zoster and Post-herpetic Neuralgia
Ocular involvement in an HIV-infected patient: not always an infectious disease. An interesting case without apparent cause
We describe the case of a young girl with HIV infection vertically transmitted who presented a long-lasting ocular involvement characterized by several relapses and remissions. Good viral and immunological status made infective or neoplastic facts unlike; diagnosis was really challenging and finally spontaneous remission was observed after several months. Clinical and histopathological findings made idiopathic… Continue reading Ocular involvement in an HIV-infected patient: not always an infectious disease. An interesting case without apparent cause
Cancer Letters special issue hepatobiliary cancer featuring the guest editor
Dr. Hongyang Wang received resident physician training specializing in gastroenterology in Chang-zheng Hospital of Shanghai, China. Shesubsequently studied clinical chemistry and completed her doctor degree at Ulm University, Germany (1992). In 1995, she received a post-doc training in Molecular Biology at Max-Planck Institute of Biochemistry, Germany. In the following three years, as a principal investigator,… Continue reading Cancer Letters special issue hepatobiliary cancer featuring the guest editor
New study using cryo-electron microscopy shows how potential drugs could inhibit cancer
from #ORL-AlexandrosSfakianakis via simeraentaxei on Inoreader http://ift.tt/1nrqcDA via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174 from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1OTzKQV via IFTTT
miR-101-3p reverses gemcitabine resistance by inhibition of ribonucleotide reductase M1 in pancreatic cancer
Pancreatic ductal adenocarcinoma (PDA) is among the most lethal malignancies and the resistance to chemotherapy prevents the therapeutic outcome. MicroRNAs provide a novel therapeutic strategy. Here, the established and primary human PDA cell lines PANC-1, AsPC-1, MIA-PaCa2, AsanPaCa, BxPC-3 and three gemcitabine-resistant subclones were examined. A gene expression profiling revealed that the ribonucleotide reductase M1… Continue reading miR-101-3p reverses gemcitabine resistance by inhibition of ribonucleotide reductase M1 in pancreatic cancer
The reverse abdominal reduction and the “waistcoating” procedure for the correction of the fixated pfannenstiel incision
The principles of a standard abdominal reduction are well understood and as a technique it has been used for many years. There are occasions, however, where, for example, an abdominal reduction has already been carried out but continued weight loss has led to skin redundancy on the upper abdomen or in cases where the upper… Continue reading The reverse abdominal reduction and the “waistcoating” procedure for the correction of the fixated pfannenstiel incision
mRNA export protein THOC5 as a tool for identification of target genes for cancer therapy.
• Recent evidence indicates that mRNA export is selective, giving priority to a subset of mRNAs that control diverse biological processes including cell proliferation, differentiation, stress response, and cell survival as well as tumor development.• Recent exosome sequence data revealed that over 100 driver gene mutations with a number of signaling pathways are involved in… Continue reading mRNA export protein THOC5 as a tool for identification of target genes for cancer therapy.
Previously published midazolam–alfentanil response surface model cannot predict patient response well in gastro intestinal endoscopy sedation
A response surface model is a mathematical model used to predict multiple-drug pharmacodynamic interactions. With the use of a previously published volunteer model, we tested the accuracy of the midazolam–alfentanil response surface model during gastrointestinal endoscopy. from #ORL-AlexandrosSfakianakis via simeraentaxei on Inoreader http://ift.tt/1SN98oE via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 &… Continue reading Previously published midazolam–alfentanil response surface model cannot predict patient response...περισσότερα »
Radiogenomics – current status, challenges and future directions
• Radiogenomics is a scientific field related to radiobiology• It addresses associations between genetic variants and normal tissue radiosensitivity• More than 130 original papers have been published on this topic• Several compelling associations have been reported from #ORL-AlexandrosSfakianakis via simeraentaxei on Inoreader http://ift.tt/1Ke7R7a via IFTTT
Fascicle length does increase in response to longitudinal resistance training and in a contraction-mode specific manner
No description available from #ORL-AlexandrosSfakianakis via simeraentaxei on Inoreader http://ift.tt/1nrpyG1 via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174 from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1OTzJwq via IFTTT
Differential effects of suppressors on hazardous sound pressure levels generated by AR-15 rifles: Considerations for recreational shooters, law enforcement, and the military
10.3109/14992027.2015.1122241<br>Edward Lobarinas from #Audiology via xlomafota13 on Inoreader http://ift.tt/1nC2eGi via IFTTT
Effects of low speed wind on the recognition/identification and pass-through communication tasks of auditory situation awareness afforded by military hearing protection/enhancement devices and tactical communication and protective systems
10.3109/14992027.2015.1129073<br>Kichol Lee from #Audiology via xlomafota13 on Inoreader http://ift.tt/1nC2d55 via IFTTT
Non-invasive imaging of oxygen extraction fraction in adults with sickle cell anaemia
Sickle cell anaemia is a monogenetic disorder with a high incidence of stroke. While stroke screening procedures exist for children with sickle cell anaemia, no accepted screening procedures exist for assessing stroke risk in adults. The purpose of this study is to use novel magnetic resonance imaging methods to evaluate physiological relationships between oxygen extraction fraction, cerebral blood flow, and clinical markers of cerebrovascular impairment in adults with sickle cell anaemia. The specific goal is to determine to what extent elevated oxygen extraction fraction may be ... περισσότερα »
Deaf, blind or deaf-blind: Is touch enhanced?
Abstract When someone looses one type of sensory input, s/he may compensate by using the sensory information conveyed by other senses. To verify whether loosing a sense or two has consequences on a spared sensory modality, namely touch, and whether these consequences depend on the type of sensory loss, we investigated the effects of deafness and blindness on temporal and spatial tactile tasks in deaf, blind and deaf-blind people. Deaf and deaf-blind people performed the spatial tactile task better than the temporal one, while blind and controls showed the opposite pattern. Deaf and... περισσότερα »
Modification to facilitate the wearing of spectacles by patient after reconstruction with a paramedian forehead pedicled flap
Paramedian forehead pedicled flaps are used for the reconstruction of large nasal and paranasal defects. Traditionally, surgeons divide and inset the pedicle 4-6 weeks after the initial operation.1 For patients, this period can be particularly difficult. from #ΓναθοΧειρουργική via xlomafota13 on Inoreader http://ift.tt/1OTz1z7 via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
Expression of cell adhesion molecule CD44 in mucoepidermoid carcinoma and its association with the tumor behavior
Background: The most common malignant salivary gland tumors that affect both adult and children is mucoepidermoid carcinoma. It usually affects both minor and major salivary glands but parotid gland is considering the most common site in which this tumor arises. CD44, a trans-membrane glycoprotein, is an adhesion molecule of cell surface that play a role in the connections between cell-cell and cell-matrix. Many malignant tumors express high levels of CD44, thus, CD44 may be used as an indicator of aggressive behavior of some human malignancy. We evaluate CD44 expression in differ...περισσότερα »
Prospective assessment of CAD/CAM zirconia abutment and lithium disilicate crown restorations:
Publication date: Available online 28 January 2016 *Source:*The Journal of Prosthetic Dentistry Author(s): Lyndon F. Cooper, Clark Stanford, Jocelyne Feine, Michael McGuire Statement of problemSingle-tooth implant restorations are commonly used to replace anterior maxillary teeth. The esthetic, functional, and biologic outcomes are, in part, a function of the abutment and crown.PurposeThe purpose of this clinical study was to describe the implant, abutment, and crown survival and complication rates for CAD/CAM zirconia abutment and lithium disilicate crown restorations for single-too...περισσότερα »
Ocular involvement in an HIV-infected patient: not always an infectious disease. An interesting case without apparent cause
We describe the case of a young girl with HIV infection vertically transmitted who presented a long-lasting ocular involvement characterized by several relapses and remissions. Good viral and immunological status made infective or neoplastic facts unlike; diagnosis was really challenging and finally spontaneous remission was observed after several months. Clinical and histopathological findings made idiopathic… Continue reading Ocular involvement in an HIV-infected patient: not always an infectious disease. An interesting case without apparent cause
New study using cryo-electron microscopy shows how potential drugs could inhibit cancer
from #ORL-AlexandrosSfakianakis via simeraentaxei on Inoreader http://ift.tt/1nrqcDA via IFTTT
Previously published midazolam–alfentanil response surface model cannot predict patient response well in gastro intestinal endoscopy sedation
A response surface model is a mathematical model used to predict multiple-drug pharmacodynamic interactions. With the use of a previously published volunteer model, we tested the accuracy of the midazolam–alfentanil response surface model during gastrointestinal endoscopy. from #ORL-AlexandrosSfakianakis via simeraentaxei on Inoreader http://ift.tt/1SN98oE via IFTTT
The reverse abdominal reduction and the “waistcoating” procedure for the correction of the fixated pfannenstiel incision
The principles of a standard abdominal reduction are well understood and as a technique it has been used for many years. There are occasions, however, where, for example, an abdominal reduction has already been carried out but continued weight loss has led to skin redundancy on the upper abdomen or in cases where the upper… Continue reading The reverse abdominal reduction and the “waistcoating” procedure for the correction of the fixated pfannenstiel incision
Fascicle length does increase in response to longitudinal resistance training and in a contraction-mode specific manner
No description available from #ORL-AlexandrosSfakianakis via simeraentaxei on Inoreader http://ift.tt/1nrpyG1 via IFTTT
Food allergies can persist after myeloablative hematopoietic stem cell transplantation in dedicator of cytokinesis 8–deficient patients
Dedicator of cytokinesis 8 (DOCK8) deficiency is a highly morbid combined immunodeficiency that features recurrent sinopulmonary infections, viral skin infections, and severe food allergies.1,2 Hematopoietic stem cell transplantation (HSCT) cures infection susceptibility in patients with DOCK8 deficiency.3-7 Whether HSCT also cures food allergy has not been systematically examined in human subjects.8 To gain insight into… Continue reading Food allergies can persist after myeloablative hematopoietic stem cell transplantation in dedicator of cytokinesis 8–deficient patients
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