Aim: This study was designed to evaluate the role of single session autologous facial fat grafting in correcting facial asymmetries after mixing it with platelet-rich fibrin (PRF) and injecting them into rich vascular facial muscular plane. Materials and Methods: Fifteen patients (12 females and 3 males) with age ranging from 18 years to 40 years were included in this study and followed up during 6 months, all the patients were treated in the Al-Shaheed Ghazi Al-Hariri for specialized surgeries hospital (Medical City, Baghdad, Iraq). Autologous fat with PRF injected in facial muscular plane was the standardized method in the treatment of acquired and congenital facial defects. Results were evaluated by 2 plastic surgeons using visual analogue scale. Interexaminer and intraexaminer calibration of the visual analogue scale were carried out by using paired t test. Results: This prospective study showed that the majority of patients (73.3%) needed only a single session for creating a noticeable improvement in facial volumes and contours. Conclusions: Mixing fat with PRF and injecting them by using facial autologous muscular injection technique offers better graft survival by utilizing the growth factors and cytokines in PRF clot together with rich vascular plexus in the muscular layer consequently. Address correspondence and reprint requests to Ahmed Fadhil Al-Quisi, BDS, FIBMS, Lecturer in Oral and Maxilloficial Department, Collage of Dentisty, Baghdad University, Baghdad, Alshaab, 0964, Iraq; E-mail: ahmedquisi@gmail.com Received 27 November, 2016 Accepted 11 November, 2017 The authors report no conflicts of interest. © 2018 by Mutaz B. Habal, MD.
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