Fine-needle aspiration biopsy
Surgeon-performed ultrasound guided fine-needle aspirate biopsy with report of learning curve; a consecutive case-series study by Vinay Fernandes via Journal of Otolaryngology - Head & Neck Surgery Background: Fine-needle aspiration biopsy has become the standard of care for the evaluation of thyroid nodules. More recently, the use of ultrasound guided fine-needle aspiration biopsy (UG-FNAB) has improved adequacy of sampling. Now there has been improved access to UG-FNAB as ultrasound technology has become more accessible. Here we review the adequacy rate and learning curve of a singl... περισσότερα »
World Allergy Organization anaphylaxis guidelines
2015 update of the evidence base: by F. Simons via World Allergy Organization Journal - Latest Articles The World Allergy Organization (WAO) Guidelines for the assessment and management of anaphylaxis provide a unique global perspective on this increasingly common, potentially life-threatening disease. Recommendations made in the original WAO Anaphylaxis Guidelines remain clinically valid and relevant, and are a widely accessed and frequently cited resource. In this 2015 update of the evidence supporting recommendations in the Guidelines, new information based on anaphylaxis publicat...περισσότερα »
Expression of prostaglandin E2 and EP receptors in human papillary thyroid carcinoma
Expression of prostaglandin E2 and EP receptors in human papillary thyroid carcinoma via Tumor Biology AbstractThe objective of the present study is to determine the role of prostaglandin E2 (PGE2) and downstream EP receptors in the development of human papillary thyroid carcinoma (PTC). A total of 90 thyroid specimens excised from patients undergoing total or subtotal thyroidectomy in the Department of General Surgery, the Fifth Affiliated Hospital of Sun Yat-sen University, China, from August 2013 to September 2014, were analyzed. The quantitative reverse transcription–polymerase c...περισσότερα »
The upregulation of miRNA-146a inhibited biological behaviors of ESCC through inhibition of IRS2
The upregulation of miRNA-146a inhibited biological behaviors of ESCC through inhibition of IRS2 via Tumor Biology AbstractIn recent years, microRNAs, also called as miRNAs, play an important role in carcinogenesis, and the dysregulation of miRNAs is closely associated with cancer progression. Till now, little has been known about the role of miRNA-146a in the esophageal squamous cell carcinomas (ESCC). In the present study, we used in vitro assays to investigate the mechanisms of miRNA-146a in ESCC cell lines and 60 ESCC tissues. Here, we found that miRNA-146a expression is downregu... περισσότερα »
ESCC : Endostatin combined with radiotherapy suppresses vasculogenic mimicry formation through inhibition of epithelial–mesenchymal transition
in esophageal cancer via Tumor Biology AbstractThe growth of solid tumors requires angiogenesis to provide oxygen and nutrients and to support cell proliferation. The switch from an avascular to a vascular phenotype is typically related to acceleration of tumor growth. Anti-angiogenic therapy is becoming a very promising way for malignant tumors. Meanwhile, malignant tumor cells themselves were able to develop the formation of cell-lined vessels that contribute to tumor neovascularization and supply the nutrients and oxygen, which is called vasculogenic mimicry (VM). However, the mo...περισσότερα »
College Students With Autism Spectrum Disorder
Assessment Considerations for by Hewitt, Lynne E. via Topics in Language Disorders - Current Issue As more students identified with autism spectrum disorders (ASD) graduate high school and aspire to a college education, the need for intervention and support targeted to their needs has become apparent. Designing effective programs of support rests on comprehensive and appropriate assessment. This article provides a critical review of areas to consider in clinical assessment of language, communication, and related areas by the speech–language pathologist working with adolescents and yo... περισσότερα »
Students with Autism Spectrum Disorders in Postsecondary Education
Implementing a Communication Coaching Program for by Weiss, Amy L.; Rohland, Pamela via Topics in Language Disorders - Current Issue This article describes the operation of a Communication Coaching Program, which was designed to provide supports for students with autism spectrum disorders (ASDs) attending the University of Rhode Island. To succeed in college programs, many students with ASDs need access to specialized programming and personnel who are able to foster their success in both social and academic venues. The Communication Coaching Program has utilized the principles of in... περισσότερα »
Students With Language Impairments
Understanding the Context: Postsecondary Challenges for by Frink, Melissa Daniel; Whitmire, Kathleen A.; Bogdan, Georgiann via Topics in Language Disorders - Current Issue [image: image] A growing number of high school students with disabilities are planning to continue their education in postsecondary schools, including vocational and career schools, 2- and 4-year colleges, and universities (U.S. Department of Education, Office for Civil Rights, 2011). The transition from secondary settings to postsecondary settings presents unique challenges for students with language impairments a...περισσότερα »
Writing Difficulties in College Students With Language Disorders and/or Learning Disabilities
Characteristics, Assessment, and Treatment of by Richards, Stephanie A. via Topics in Language Disorders - Current Issue Many students currently are enrolled in colleges and universities across the country with language disorders and/or learning disabilities (LLD). The majority of these students struggle with writing, creating a need to identify and provide them with writing intervention services. Speech–language pathologists (SLPs) may provide this intervention; however, many report lacking the confidence, training, and experience to assess and treat writing difficulties in this or ... περισσότερα »
Antidepressants increase the risk of breast cancer or recurrence
Assessing the Risks Associated with Antidepressant Use in Plastic Surgery: A Systematic Review by Teo, Isabel; Song, Christopher Tam via Plastic and Reconstructive Surgery - Current Issue [image: image]Background: Antidepressant use has increased dramatically over the past decade. Although there is no question about the benefits of these medications, uncertainty exists with regard to the implications of antidepressant treatment surrounding plastic surgery. This systematic review collates all of the available literature that evaluates the risks of patient antidepressant treatment, in ... περισσότερα »
The Plastic and Reconstructive Surgery iPad Cosmetic Surgery App
Mastering Cosmetic Surgery: Reflections on [image: Collapse Box]Author Information Section of Plastic and Reconstructive Surgery, Yale University School of Medicine, New Haven, Conn. Correspondence to Dr. Patel, The Institute of Reconstructive Plastic Surgery, New York University Medical Center, New York, N.Y. 10016, anup.patel@nyumc.org If people knew how hard I had to work to gain my *mastery*, it would not seem so wonderful at all. —Michelangelo Sir: Aesthetic plastic surgery demands perfection.1 Every move must be precise, every cut must be accurate, and every suture placed must... περισσότερα »
Face Lift
Face Lift by Wan, Dinah; Small, Kevin H.; Barton, Fritz E. via Plastic and Reconstructive Surgery - Current Issue [image: image]Learning Objectives: After studying this article, the participant should be able to: 1. Identify the essential anatomy of the aging face and its relationship to face-lift surgery. 2. Understand the common operative approaches to the aging face and a historical perspective. 3. Understand and describe the common complications following face lifting and treatment options. Summary: Surgical rejuvenation of the aging face remains one of the most commonly performe... περισσότερα »
Quality Care in the Treatment of Skin Lesions
Plastic & Reconstructive Surgery: November 2015 - Volume 136 - Issue 5 - p 719e–720e doi: 10.1097/PRS.0000000000001667 Viewpoints Quality Care and the Plastic Surgeon’s Role in the Treatment of Skin Lesions Cabbabe, Edmond B. M.D. Free Access Article Outline [image: Collapse Box]Author Information Advanced Plastic Surgery, Inc., 10004 Kennerly Road, 365B, St. Louis, Mo. 63128,ebcsl@aol.com Sir: The Centers for Medicare & Medicaid Services states that the majority of skin cancers can be managed by simple excision or destruction techniques.1 Plastic surgeons have historically provided cos...περισσότερα »
Normal Saline and an Antiseptic Solution for Negative-Pressure Wound Therapy with Instillation
Comparison of Outcomes for by Kim, Paul J.; Attinger, Christopher E.; Oliver, Noah; Garwood, Caitlin; Evans, Karen K.; Steinberg, John S.; Lavery, Larry A. viaPlastic and Reconstructive Surgery - Current Issue [image: image]Background: Negative-pressure wound therapy with instillation is an adjunctive treatment that uses periodic instillation of a solution and negative pressure for a wide diversity of wounds. A variety of solutions have been reported, with topical antiseptics as the most frequently chosen option. The objective of this study was to compare the outcomes of normal sali... περισσότερα »
Is Inferior Turbinate Lateralization Effective?
Plastic & Reconstructive Surgery: November 2015 - Volume 136 - Issue 5 - p 710e–711e doi: 10.1097/PRS.0000000000001687 Viewpoints Moss, William J. M.D.; Lemieux, Aaron J. B.S.; Alexander, Thomas H. M.D. Free Access Article Outline [image: Collapse Box]Author Information Department of Surgery, Division of Otolaryngology–Head and Neck Surgery, University of California, San Diego, San Diego, Calif. Correspondence to Dr. Moss, Department of Otolaryngology–Head and Neck Surgery, University of California, San Diego, 200 West Arbor Drive, San Diego, Calif. 92103,billy.moss85@gmail.com Sir: Usu...περισσότερα »
Noninvasive Monitoring of Immune Rejection in Face Transplant Recipients
Noninvasive Monitoring of Immune Rejection in Face Transplant Recipients by Kueckelhaus, Maximilian; Imanzadeh, Amir; Fischer, Sebastian; Kumamaru, Kanako; Alhefzi, Muayyad; Bueno, Ericka; Wake, Nicole; Gerhard-Herman, Marie D.; Rybicki, Frank J.; Pomahac, Bohdan via Plastic and Reconstructive Surgery - Current Issue Background: Chronic rejection leading to allograft loss remains a significant concern after facial allotransplantation. Chronic rejection may occur without clinical signs or symptoms. The current means of monitoring is histologic analyses of allograft biopsy specimens, wh...περισσότερα »
Fat Grafting in Primary Cleft Lip Repair
Plastic & Reconstructive Surgery: November 2015 - Volume 136 - Issue 5 - p 708e doi: 10.1097/PRS.0000000000001665 Letters Idone, Francesco M.D.; Sisti, Andrea M.D.; Tassinari, Juri M.D.; Nisi, Giuseppe M.D. Free Access Article Outline [image: Collapse Box]Author Information Jalisco Plastic and Reconstructive Institute, University of Guadalajara, Guadalajara, Jalisco, Mexico General and Specialist Surgery Department, Plastic Surgery Division, University of Siena, Siena, Italy Correspondence to Dr. Idone, Jalisco Plastic and Reconstructive Institute, University of Guadalajara, Avenida Fed... περισσότερα »
Gustatory Sweating Syndrome : Intraparotid Location of the Great Auricular Nerve
Intraparotid Location of the Great Auricular Nerve: A New Anatomical Basis for Gustatory Sweating Syndrome by Toure, Gaoussou via Plastic and Reconstructive Surgery - Current Issue [image: image]Background: Gustatory sweating syndrome (also known as Frey syndrome or auriculotemporal nerve syndrome) is thought to result from a lesion of the auriculotemporal nerve. A lesion of this nerve can lead to aberrant regeneration of nerve fibers to the sweat glands and blood vessels. The occurrence of signs outside the region of the auriculotemporal nerve prompted the author to search for anothe...περισσότερα »
Malar Augmentation with Pedicled Buccal Fat Pad in Orthognathic Surgery
: Three-Dimensional Evaluation by Hernández-Alfaro, Federico; Valls-Ontañón, Adaia; Blasco-Palacio, Julia C.; Guijarro-Martínez, Raquel via Plastic and Reconstructive Surgery - Current Issue [image: image] Background: Contemporary orthognathic surgery contemplates three-dimensional facial soft-tissue harmonization as one of the basic pillars in treatment planning. In particular, prominent malar regions are regarded as a sign of beauty and youth by Western societies. The aim of this article was to perform a subjective and objective three-dimensional evaluation of the pedicled buccal f... περισσότερα »
Orbital Dysmorphology in Untreated Children with Crouzon and Apert Syndromes
Plastic & Reconstructive Surgery: November 2015 - Volume 136 - Issue 5 - p 1054–1062 doi: 10.1097/PRS.0000000000001693 Pediatric/Craniofacial: Original Articles Forte, Antonio Jorge M.D.; Steinbacher, Derek M. M.D., D.M.D.; Persing, John A. M.D.; Brooks, Eric D. B.S.; Andrew, Tom W. M.B.Ch.B.; Alonso, Nivaldo M.D., Ph.D. [image: Collapse Box]Abstract Background: Orbital dysmorphology and midface retrusion are the hallmarks of Crouzon and Apert syndromes. The precise nature of this deficiency is not known. Methods: Untreated Crouzon and Apert syndrome patients and age- and sex-matched c... περισσότερα »
Lip Height Symmetry
The Use of an Inferior Pennant Flap during Unilateral Cleft Lip Repair Improves Lip Height Symmetry by Russell, Aaron J.; Patel, Kamlesh B.; Skolnick, Gary B.; Woo, Albert S. via Plastic and Reconstructive Surgery - Current Issue [image: image] Background: To improve the rotation of Cupid’s bow and achieve sufficient vertical lip height, several variations of the Millard rotation-advancement have incorporated a small laterally based triangular flap above the cutaneous roll. This study uses three-dimensional photogrammetry to evaluate the outcomes of unilateral cleft lip repairs perfor... περισσότερα »
Columellar Strut Graft in Primary Open Approach Rhinoplasty
Revisiting the Role of [image: Collapse Box]Author Information Jalisco Plastic and Reconstructive Institute, University of Guadalajara, Guadalajara, Jalisco, Mexico Plastic Surgery Division, General and Specialist Surgery Department, University of Siena, Siena, Italy Correspondence to Dr. Idone, Jalisco Plastic and Reconstructive Institute, University of Guadalajara, Avenida Federalismo Norte 2022, Guadalajara, Jalisco, México,francescoidone81@hotmail.it Sir: We have read with great interest the article entitled “Revisiting the Role of Columellar Strut Graft in Primary Open Approach... περισσότερα »
Unilateral Cleft Lip and Palate : Permanent Tooth Agenesis and Maxillary Hypoplasia
Permanent Tooth Agenesis and Maxillary Hypoplasia in Patients with Unilateral Cleft Lip and Palate by Antonarakis, Gregory S.; Fisher, David M. via Plastic and Reconstructive Surgery - Current Issue [image: image] Abstract Background: Maxillary growth in patients with clefts is highly variable. The authors’ aim was to investigate whether severity of maxillary hypoplasia is associated with the presence of permanent tooth agenesis in children with complete unilateral cleft lip and palate. Methods: Fifty children with complete unilateral cleft lip and palate were divided into two groups ... περισσότερα »
Mandibular Distraction Osteogenesis in Low-Weight Neonates with Robin Sequence
: Is It Safe? by Tahiri, Youssef; Greathouse, S. Travis; Tholpady, Sunil S.; Havlik, Robert; Sood, Rajiv; Flores, Roberto L. via Plastic and Reconstructive Surgery - Current Issue Background: The aim of this study was to evaluate the efficacy, safety profile, and complications associated with mandibular distraction osteogenesis performed in infants weighing less than 4 kg with Robin sequence. Methods: An 11-year retrospective review of all infants (younger than 6 months) with mandibular distraction osteogenesis–treated Robin sequence was performed. Patients weighing less than 4 kg (e... περισσότερα »
Fame Fortune Family : Shaping a Career in Plastic Surgery
: Balancing the “Three Fs” by Hidalgo, David A. via Plastic and Reconstructive Surgery - Current Issue [image: image]
Financial Conflicts of Interest
: An Association between Funding and Findings in Plastic Surgery Abstract Background: Despite a growing interest in examining the effects of industry funding on research in plastic surgery, no study to date has comprehensively examined the effects of financial conflicts of interest on publication outcomes. The authors investigated the association between financial conflicts of interest and reported study findings in plastic surgery research. Methods: The authors reviewed all entries in *Plastic and Reconstructive Surgery*, *Annals of Plastic Surgery*, and *Journal of Plastic, Recons... περισσότερα »
The Profunda Artery Perforator Flap
: Investigating the Perforasome Using Three-Dimensional Computed Tomographic Angiography by Wong, Corrine; Nagarkar, Purushottam; Teotia, Sumeet; Haddock, Nicholas T. via Plastic and Reconstructive Surgery - Current Issue Background: The profunda artery perforator flap has been emerging as an alternative method of autologous breast reconstruction. This flap uses upper posterior thigh tissue. The profunda artery perforator perforasome is investigated using three-dimensional computed tomographic angiography. Methods: Ten cadaveric thighs were dissected centered over the profunda artery...περισσότερα »
Fibroblast-Specific Deletion of Hypoxia Inducible Factor-1 Critically Impairs Cutaneous Neovascularization and Wound Healing
Fibroblast-Specific Deletion of Hypoxia Inducible Factor-1 Critically Impairs Murine Cutaneous Neovascularization and Wound Healing by Duscher, Dominik; Maan, Zeshaan N.; Whittam, Alexander J.; Sorkin, Michael; Hu, Michael S.; Walmsley, Graham G.; Baker, Hutton; Fischer, Lauren H.; Januszyk, Michael; Wong, Victor W.; Gurtner, Geoffrey C. via Plastic and Reconstructive Surgery - Current Issue [image: image] B Abstract Background: Diabetes and aging are known risk factors for impaired neovascularization in response to ischemic insult, resulting in chronic wounds, and poor outcomes follo... περισσότερα »
Bone Marrow Stromal Cell Sheets in Maintaining Random-Pattern Skin Flaps
Effectiveness of Bone Marrow Stromal Cell Sheets in Maintaining Random-Pattern Skin Flaps in an Experimental Animal Model by Kira, Tsutomu; Omokawa, Shohei; Akahane, Manabu; Shimizu, Takamasa; Nakano, Kenichi; Nakanishi, Yasuaki; Onishi, Tadanobu; Kido, Akira; Inagaki, Yusuke; Tanaka, Yasuhito via Plastic and Reconstructive Surgery - Current Issue [image: image] Abstract Background: Bone marrow stromal cells can be applied therapeutically to enhance angiogenesis; however, the use of bone marrow stromal cell suspensions reduces efficiency because of low-level attachment. The authors h... περισσότερα »
Burn Injury and Trauma on Muscle and Bone Mass and Composition
The Systemic Effect of by Rinkinen, Jacob; Hwang, Charles D.; Agarwal, Shailesh; Oluwatobi, Eboda; Peterson, Jonathan; Loder, Shawn; Brownly, Robert C.; Cummings, Timothy; Cederna, Paul S.; Levi, Benjamin via Plastic and Reconstructive Surgery - Current Issue [image: image]Background: By understanding the global inflammatory effects on distant myopathies, surgeons can better guide the rehabilitative process for burn patients. The authors tested the systemic effect of burn injury on distant injured muscle and native bone using immunohistochemistry and validated a new morphometric ana...περισσότερα »
Fibroproliferative Scarring,Dermal Fibroblasts from the Red Duroc Pig
Dermal Fibroblasts from the Red Duroc Pig Have an Inherently Fibrogenic Phenotype: An In Vitro Model of Fibroproliferative Scarring by Sood, Ravi F.; Muffley, Lara A.; Seaton, Max E.; Ga, Maricar; Sirimahachaiyakul, Pornthep; Hocking, Anne M.; Gibran, Nicole S. viaPlastic and Reconstructive Surgery - Current Issue [image: image] Background: The pathophysiology of hypertrophic scarring is unknown in part because of the lack of a robust animal model. Although the red Duroc pig has emerged as a promising in vivo model, the cellular mechanisms underlying Duroc scarring are unknown, and th...περισσότερα »
The Collagenase of the Bacterium Clostridium histolyticum for the Treatment of Capsular Fibrosis
after Silicone Implants by Fischer, Sebastian; Hirsch, Tobias; Diehm, Yannick; Kiefer, Jurij; Bueno, Ericka M.; Kueckelhaus, Maximilian; Kremer, Thomas; Hirche, Christoph; Kneser, Ulrich; Pomahac, Bohdan via Plastic and Reconstructive Surgery - Current Issue Background: The main part of the fibrotic capsule in capsular contracture is collagen. The collagenase of the bacterium Clostridium histolyticum is U.S. Food and Drug Administration approved for the treatment of Dupuytren contracture and might be capable of dissolving the fibrotic capsule surrounding silicone implants. Methods: ...περισσότερα »
Eyelid Finger Manipulation in the Treatment of Overcorrected Blepharoptosis and Postblepharoplasty Ectropion-Retraction
Reply: Eyelid Finger Manipulation in the Treatment of Overcorrected Blepharoptosis and Postblepharoplasty Ectropion-Retraction by Putterman, Allen M. via Plastic and Reconstructive Surgery - Current Issue [image: image]
Closed Microfracture Technique for Surgical Correction of Inferior Turbinate Hypertrophy in Rhinoplasty
: Safety and Technical Considerations by Rohrich, Rod J.; McKee, Daniel; Malafa, Menyoli via Plastic and Reconstructive Surgery - Current Issue [image: image]Summary: An abundance of surgical procedures are in use for the management of inferior turbinate hypertrophy in rhinoplasty patients. An ideal treatment approach is elusive, given the variability of patient presentation regarding obstructive nasal airway, significant complications associated with techniques that cause mucosal trauma, and the high recurrence rates associated with more conservative techniques. In an effort to impr... περισσότερα »
Sharing and storing digital patient photographs occur daily in plastic surgery
Digital Photograph Security: What Plastic Surgeons Need to Know by Thomas, Virginia A.; Rugeley, Patricia B.; Lau, Frank H. via Plastic and Reconstructive Surgery - Current Issue Background: Sharing and storing digital patient photographs occur daily in plastic surgery. Two major risks associated with the practice, data theft and Health Insurance Portability and Accountability Act (HIPAA) violations, have been dramatically amplified by high-speed data connections and digital camera ubiquity. The authors review what plastic surgeons need to know to mitigate those risks and provide reco... περισσότερα »
Prevention of Capsular Contracture Using Leukotriene Antagonists
Prevention of Capsular Contracture Using Leukotriene Antagonists by Graf, Ruth; Ascenço, Adriana S. K.; Freitas, Renato da S.; Balbinot, Priscilla; Peressutti, Carolina; Costa, Diogo F. B.; dos Santos, Fábio de H. C. R.; Ratti, Marco A. S.; Kulchetscki, Rodrigo M. via Plastic and Reconstructive Surgery - Current Issue [image: image]Background: Capsular contracture is a common occurrence in plastic surgery, with a prevalence varying from 0.5 percent up to 30 percent. Although the standard treatment is capsulectomy, alternative treatments have been studied, such as the use of leukotrien...περισσότερα »
Optimal Augmentation of the Asian Face with Hyaluronic Acid and Calcium Hydroxylapatite Fillers
Consensus Recommendations for by Rho, Nark-Kyoung; Chang, Yao-Yuan; Chao, Yates Yen-Yu; Furuyama, Nobutaka; Huang, Peter Y. C.; Kerscher, Martina; Kim, Hee-Jin; Park, Je-Young; Peng, Hsien Li Peter; Rummaneethorn, Paisal; Rzany, Berthold; Sundaram, Hema; Wong, Chin Ho; Yang, Yuli; Prasetyo, Adri Dwi via Plastic and Reconstructive Surgery - Current Issue [image: image]Background: Although the use of filling agents for soft-tissue augmentation has increased worldwide, most consensus statements do not distinguish between ethnic populations. There are, however, significant differences b... περισσότερα »
Renal function evaluation in patients with thyroid dysfunction
The correct via Latest Results for Journal of Endocrinological Investigation AbstractThyroid dysfunction induces several renal derangements involving all nephron portions. Furthermore, dysthyroidism is a recognized risk factor associated with the development of chronic kidney disease. Current data, in fact, demonstrate that either subclinical or overt thyroid disease is associated with significant changes in creatinine, estimated glomerular filtration rate, measured glomerular filtration rate and Cystatin C. Herein, we systematically reviewed several relevant studies aiming at the i... περισσότερα »
Platelet-Rich Plasma with Basic Fibroblast Growth Factor for Treatment of Wrinkles and Depressed Areas
of the Skin by Kamakura, Tatsuro; Kataoka, Jiro; Maeda, Kazuhiko; Teramachi, Hideaki; Mihara, Hisayuki; Miyata, Kazuhiro; Ooi, Kouichi; Sasaki, Naomi; Kobayashi, Miyuki; Ito, Kouhei via Plastic and Reconstructive Surgery - Current Issue Background: There are several treatments for wrinkles and depressed areas of the face, hands, and body. Hyaluronic acid is effective, but only for 6 months to 1 year. Autologous fat grafting may cause damage during tissue harvest. Methods: In this study, patients were injected with platelet-rich plasma plus basic fibroblast growth factor (bFGF). Plate...περισσότερα »
Aspiration in individuals with amyotrophic lateral sclerosis
Discriminant ability of the Eating Assessment Tool-10 to detect by E. K. Plowman, L. C. Tabor, R. Robison, J. Gaziano, C. Dion, S. A. Watts, T. Vu, C. Gooch via The European Gastrointestinal Motility Society Abstract Background Oropharyngeal dysphagia is prevalent in individuals with amyotrophic lateral sclerosis (ALS) leading to malnutrition, aspiration pneumonia, and death. These factors necessitate early detection of at-risk patients to prolong maintenance of safe oral intake and pulmonary function. This study aimed to evaluate the discriminant ability of the Eating Assessment Tool... περισσότερα »
Effekt der mikrochirurgischen Entfernung von Vestibularisschwannomen auf das Schmeckvermögen
Effekt der mikrochirurgischen Entfernung von Vestibularisschwannomen auf das Schmeckvermögen by Boeßert, P. via Laryngo-Rhino-Otologie Laryngo-Rhino-Otol DOI: 10.1055/s-0035-1559679 Patienten mit Vestibularisschwannom berichten neben den bekannten Kardinalsymptomen auch über Schmeckstörungen. Wenig ist bisher zu diesem Symptom bei dieser Patientengruppe bekannt. Ziel dieser Untersuchung war es, den Einfluss der operativen Therapie auf das Schmeckvermögen mit Hilfe eines standardisierten Schmecktests prospektiv zu untersuchen. Dafür wurde das Schmeckvermögen mit den Schmeckstreifen vor... περισσότερα »
Postoperative Follow-up after Meningioma Resection
Factors Associated with Low Socioeconomic Status Predict Poor by Nayeri, Arash via Journal of Neurological Surgery Part B: Skull Base J Neurol Surg B DOI: 10.1055/s-0035-1566122 Objectives To quantify the rates of loss of follow-up after meningioma resection and to identify any key demographical associations. Design Retrospective cohort. Setting Vanderbilt University Medical Center, 2001–2013. Participants A total of 281 patients surgically treated for an intracranial meningioma at a single institution between 2001 and 2013. Main Outcome Measures Patient clinical follow-up within the ... περισσότερα »
Improved skin flap survival with the use of adipose-derived stem cells
Improved skin flap survival in venous ischemia-reperfusion injury with the use of adipose-derived stem cells by Hyun Ho Han, Young Min Lim, Sang Wook Park, Su Jin Lee, Jong Won Rhie, Jung Ho Lee via Microsurgery Introduction The purpose of this study was to investigate the efficacy of stem cell therapy as an adjuvant treatment for congested skin flap. Method Sprague-Dawley rats (*n* = 21) were randomized into three groups. In group I, the flap was sutured without venous ischemia. In group II, the vein was selectively clamped for 4 hours, and complete medium was administered upon clamp...περισσότερα »
Active thermoregulation on the microcirculation of free flaps
Impact of by Ulf Dornseifer, Andreas Max Fichter, Sarah Von Isenburg, Sofia Stergioula, Ina-Christine Rondak, Milomir Ninkovic viaMicrosurgery Background While it is a known fact that warming increases blood flow in healthy tissue, little is known about the impact of active thermoregulation on the altered microcirculation of free flaps. The objective of the study was to identify the impact of postoperative active thermoregulation on free flap microcirculation. Methods Tissue temperature was assessed in 25 free perforator flaps using an implanted probe. Active thermoregulation was ach... περισσότερα »
Adenoidal follicular T helper cells
provide stronger B-cell help than those from tonsils by Matthew C. Morris, Kevin Kozara, Frank Salamone, Margo Benoit, Michael E. Pichichero via The Laryngoscope Objectives/Hypothesis The tonsils and adenoids are secondary lymphoid organs, where antigen processing and immune cell development occur to control bacterial colonization and infection in the upper respiratory tract. Both organs are abundant in follicular T helper cells (TFH), a subset of T cells specialized for promoting B-cell development. There are no prior studies on differences between the immune cells of the tonsils an...περισσότερα »
Non-dystonic embouchure problems (NED) versus embouchure dystonia (ED)
Evaluation of embouchure dysfunction: Experience of 139 patients at a single center by Pichet Termsarasab, Steven J. Frucht via The Laryngoscope Objectives/Hypothesis Our aims are to 1) illustrate the complexity and phenomenological richness of the embouchure; 2) delineate the main clinical features of non-dystonic embouchure problems (NED) versus embouchure dystonia (ED); and 3) provide a practical framework for physicians who may encounter a patient with embouchure dysfunction. Study Design We performed retrospective chart and video review and report 139 instrumentalists with embouc... περισσότερα »
E-cadherin and β-catenin overexpression in laryngeal squamous cell carcinoma
The prognostic role of by Antonio Greco, Armando De Virgilio, Maria Ida Rizzo, Fabio Pandolfi, Davide Rosati, Marco de Vincentiis via The Laryngoscope Objectives/Hypothesis Epithelial-to-mesenchymal transition (EMT) consists of a rapid and reversible change in the cellular phenotype toward the mesenchymal cell phenotype that facilitates cell migration and invasion of the tumor into surrounding tissues followed by metastasis. In the present study, we sought to determine the clinical significance of E-cadherin, N-cadherin, β-catenin, α-catenin, γ-catenin, caveolin-1, and vimentin in a ... περισσότερα »
Adenoid cystic carcinoma,adenocarcinoma,acinic cell carcinoma,basal cell adenocarcinoma, carcinoma-ex-pleomorphic adenoma,mucoepidermoid carcinoma and salivary duct carcinoma
Outcome analysis of 215 patients with parotid gland tumors: a retrospective cohort analysis by Boban Erovic via Journal of Otolaryngology - Head & Neck Surgery Background: To identify prognostic factors in patients with parotid gland carcinomas who were treated at the Princess Margaret Hospital. Methods: Clinical outcome of two hundred fifteen patients with malignancies of the parotid gland was evaluated over a 16-year period. Results: Two-hundred-fifteen patients with adenoid cystic carcinoma (n = 20), adenocarcinoma (n = 19), acinic cell carcinoma (n = 62), basal cell adenocarcinom...περισσότερα »
Allergic Fungal Rhinosinusitis and the Unified Airway
: the Role of Antifungal Therapy in AFRS via Current Allergy and Asthma Reports AbstractAllergic fungal sinusitis (AFS) or rhinosinusitis (AFRS) is a form of polypoid chronic rhinosinusitis that is believed to be due to hypersensitivity to fungal antigens. The disease is characterized by type 1 hypersensitivity to fungal allergens, dramatically elevated total serum IgE, accumulation of thick eosinophil-laden mucin with non-invasive fungal hyphae within the paranasal sinuses, nasal polyposis, and sinus bony remodeling. Because of many clinicopathologic similarities to allergic broncho... περισσότερα »
Ablepharon-Macrostomia Syndrome with Amniotic Membrane Grafting
A Case Report of via COP : Last 10 articles We describe a rare case of an infant who was born with multiple congenital anomalies, including the absence of eyelids. This patient had many dysmorphic features consistent with a severe phenotype of ablepharon-macrostomia syndrome (AMS) including a fish-like appearance of the mouth, rudimentary ears, absence of body hair, thin skin, absent nipples, abdominal distension, and genital abnormalities. Upon presentation, there was severe exposure keratopathy causing large bilateral sterile ulcers culminating in corneal melting of both eyes. An ... περισσότερα »
