Emerging strategies for managing differentiated thyroid cancers refractory to radioiodine
Abstract Efficient treatment of radio refractory thyroid cancer is still a major challenge. The recent identification of genetic and epigenetic alterations present in almost all differentiated tumors has revealed novel molecular targets, which can hopefully be exploited to create new treatments for these tumors. This review looks briefly at some of the innovative strategies currently being investigated for the treatment the radioiodine-resistant thyroid cancers. from Endocrinology via ola Kala on Inoreader http://ift.tt/1OjBiXr via IFTTT
Docetaxel plus androgen deprivation withdrawal may restore sensitivity to luteinizing hormone-releasing hormone analog therapy in castration-resistant prostate cancer patients
from Endocrinology via ola Kala on Inoreader http://ift.tt/1UYw825 via IFTTT
Dehydration effects of a V2 antagonist on endolymphatic hydrops in guinea pigs
Publication date: Available online 21 December 2015 *Source:*Hearing Research Author(s): Naoya Egami, Akinobu Kakigi, Taizo Takeda, Tatsuya Yamasoba We investigated the influence of vasopressin type 2 receptor antagonist (OPC-41061; Tolvaptan) on experimentally induced endolymphatic hydrops (EH) in guinea pigs. In the first series, the endolymphatic sac (ES) of the left ear of all animals was electrocauterized. Four weeks after surgery, the animals were allocated to four groups: three systemic applications groups (saline, OPC 10 and 100 mg/kg) and a local round window (RW) OPC 1mg/body...περισσότερα »
Somatic memory and gain increase as preconditions for tinnitus: insights from congenital deafness
Publication date: Available online 21 December 2015 *Source:*Hearing Research Author(s): Jos J. Eggermont, Andrej Kral Tinnitus is the conscious perception of sound heard in the absence of physical sound sources internal or external to the body. The characterization of tinnitus by its spectrum reflects the missing frequencies originally represented in the hearing loss, i.e., partially or completely deafferented, region. The tinnitus percept, despite a total hearing loss, may thus be dependent on the persisting existence of a somatic memory for the “lost” frequencies. Somatic memory in... περισσότερα »
Dehydration effects of a V2 antagonist on endolymphatic hydrops in guinea pigs
Publication date: Available online 21 December 2015 *Source:*Hearing Research Author(s): Naoya Egami, Akinobu Kakigi, Taizo Takeda, Tatsuya Yamasoba We investigated the influence of vasopressin type 2 receptor antagonist (OPC-41061; Tolvaptan) on experimentally induced endolymphatic hydrops (EH) in guinea pigs. In the first series, the endolymphatic sac (ES) of the left ear of all animals was electrocauterized. Four weeks after surgery, the animals were allocated to four groups: three systemic applications groups (saline, OPC 10 and 100 mg/kg) and a local round window (RW) OPC 1mg/body...περισσότερα »
Somatic memory and gain increase as preconditions for tinnitus: insights from congenital deafness
Publication date: Available online 21 December 2015 *Source:*Hearing Research Author(s): Jos J. Eggermont, Andrej Kral Tinnitus is the conscious perception of sound heard in the absence of physical sound sources internal or external to the body. The characterization of tinnitus by its spectrum reflects the missing frequencies originally represented in the hearing loss, i.e., partially or completely deafferented, region. The tinnitus percept, despite a total hearing loss, may thus be dependent on the persisting existence of a somatic memory for the “lost” frequencies. Somatic memory in... περισσότερα »
Dehydration effects of a V2 antagonist on endolymphatic hydrops in guinea pigs
Publication date: Available online 21 December 2015 *Source:*Hearing Research Author(s): Naoya Egami, Akinobu Kakigi, Taizo Takeda, Tatsuya Yamasoba We investigated the influence of vasopressin type 2 receptor antagonist (OPC-41061; Tolvaptan) on experimentally induced endolymphatic hydrops (EH) in guinea pigs. In the first series, the endolymphatic sac (ES) of the left ear of all animals was electrocauterized. Four weeks after surgery, the animals were allocated to four groups: three systemic applications groups (saline, OPC 10 and 100 mg/kg) and a local round window (RW) OPC 1mg/body...περισσότερα »
Somatic memory and gain increase as preconditions for tinnitus: insights from congenital deafness
Publication date: Available online 21 December 2015 *Source:*Hearing Research Author(s): Jos J. Eggermont, Andrej Kral Tinnitus is the conscious perception of sound heard in the absence of physical sound sources internal or external to the body. The characterization of tinnitus by its spectrum reflects the missing frequencies originally represented in the hearing loss, i.e., partially or completely deafferented, region. The tinnitus percept, despite a total hearing loss, may thus be dependent on the persisting existence of a somatic memory for the “lost” frequencies. Somatic memory in... περισσότερα »
Dehydration effects of a V2 antagonist on endolymphatic hydrops in guinea pigs
Publication date: Available online 21 December 2015 *Source:*Hearing Research Author(s): Naoya Egami, Akinobu Kakigi, Taizo Takeda, Tatsuya Yamasoba We investigated the influence of vasopressin type 2 receptor antagonist (OPC-41061; Tolvaptan) on experimentally induced endolymphatic hydrops (EH) in guinea pigs. In the first series, the endolymphatic sac (ES) of the left ear of all animals was electrocauterized. Four weeks after surgery, the animals were allocated to four groups: three systemic applications groups (saline, OPC 10 and 100 mg/kg) and a local round window (RW) OPC 1mg/body...περισσότερα »
Somatic memory and gain increase as preconditions for tinnitus: insights from congenital deafness
Publication date: Available online 21 December 2015 *Source:*Hearing Research Author(s): Jos J. Eggermont, Andrej Kral Tinnitus is the conscious perception of sound heard in the absence of physical sound sources internal or external to the body. The characterization of tinnitus by its spectrum reflects the missing frequencies originally represented in the hearing loss, i.e., partially or completely deafferented, region. The tinnitus percept, despite a total hearing loss, may thus be dependent on the persisting existence of a somatic memory for the “lost” frequencies. Somatic memory in... περισσότερα »
Dehydration effects of a V2 antagonist on endolymphatic hydrops in guinea pigs
Publication date: Available online 21 December 2015 *Source:*Hearing Research Author(s): Naoya Egami, Akinobu Kakigi, Taizo Takeda, Tatsuya Yamasoba We investigated the influence of vasopressin type 2 receptor antagonist (OPC-41061; Tolvaptan) on experimentally induced endolymphatic hydrops (EH) in guinea pigs. In the first series, the endolymphatic sac (ES) of the left ear of all animals was electrocauterized. Four weeks after surgery, the animals were allocated to four groups: three systemic applications groups (saline, OPC 10 and 100 mg/kg) and a local round window (RW) OPC 1mg/body...περισσότερα »
Somatic memory and gain increase as preconditions for tinnitus: insights from congenital deafness
Publication date: Available online 21 December 2015 *Source:*Hearing Research Author(s): Jos J. Eggermont, Andrej Kral Tinnitus is the conscious perception of sound heard in the absence of physical sound sources internal or external to the body. The characterization of tinnitus by its spectrum reflects the missing frequencies originally represented in the hearing loss, i.e., partially or completely deafferented, region. The tinnitus percept, despite a total hearing loss, may thus be dependent on the persisting existence of a somatic memory for the “lost” frequencies. Somatic memory in... περισσότερα »
Comparative effectiveness of fungicidal vs. fungistatic therapies for the treatment of paediatric candidaemia
Summary Adult data suggest that echinocandins for treatment of candidaemia are associated with decreased mortality, attributed to their fungicidal activity. There are limited data comparing antifungals in children. We compared 30-day all-cause mortality among paediatric candidaemia patients treated with fungicidal vs. fungistatic agents. All inpatients (>6 months and <19 years of age) with candidaemia between 2000 and 2012 at The Children's Hospital of Philadelphia were retrospectively identified. Definitive therapy with fungicidal (amphotericin B and caspofungin) agents was compa...περισσότερα »
Fibula free flap for complex oromandibular reconstruction
There is no donor side specificity of fibula free flap for complex oromandibular reconstruction: *Prabha S Yadav, Quazi G Ahmad, Vinay Kant Shankhdhar, GI Nambi* Indian Journal of Plastic Surgery 2010 43(2):177-180 Background: The objective of this study was to prove that there is no significance to the donor side (right or left) of the free fibula osteocutaneous flap (FFOCF) in the reconstruction of complex oromandibular defects (COMD) and proper flap planning, designing and tailoring are important in reconstructing different types of COMD after tumour-ablative surgery. Materi... περισσότερα »
Benign symmetric lipomatosis of Launois–Bensaude, Madelung's disease, multiple symmetric lipomatosis and cephalothoracic lipodystrophy
Benign symmetric lipomatosis From Wikipedia, the free encyclopedia Benign symmetric lipomatosis[image: Benign symmetric lipomatosis.JPG] A young man with benign symmetric lipomatosis (Madelung's disease) of idiopathic etiology Classification and external resourcesSpecialtyendocrinologyICD-10E88.8 (ILDS E88.820)OMIM151800MeSHD008069 *Benign symmetric lipomatosis* (also known as *Benign symmetric lipomatosis of Launois–Bensaude*, *Madelung's disease*, *multiple symmetric lipomatosis* and *cephalothoracic lipodystrophy*) is a cutaneous condition characterized by extensive symmetric fat d...περισσότερα »
Septal rhinoscleroma
Septal rhinoscleroma: *Mohamed A Shoeib* Indian Journal of Plastic Surgery 2010 43(2):219-221 Rhinoscleroma is a chronic granulomatous condition of the nose and other structures of the upper respiratory tract. Infection by the bacterium Klebsiella rhinoscleromatis is said to be the cause. A female patient aged 45 years, presented with a past history of trauma to the nose and swelling on her nose since last 1 year. There was nasal asymmetry and internal nasal examination showed a septal swelling protruding to the right nasal cavity with hypertrophied nasal mucosa and inferior tur... περισσότερα »
Perforator plus flaps: The tenuous blood supply of traditional flaps for wound cover combined with collateral damage by sacrifice of functional muscle, truncal vessels, or nerves has been the bane of reconstructive procedures
Perforator plus flaps: Optimizing results while preserving function and esthesis: *Sandeep Mehrotra* Indian Journal of Plastic Surgery 2010 43(2):141-148 Background: The tenuous blood supply of traditional flaps for wound cover combined with collateral damage by sacrifice of functional muscle, truncal vessels, or nerves has been the bane of reconstructive procedures. The concept of perforator plus flaps employs dual vascular supply to flaps. By safeguarding perforators along with supply from its base, robust flaps can be raised in diverse situations. This is achieved while limit... περισσότερα »
Piercing ears
Sir, Ear piercing is done mostly for aesthetic reasons but in our country, it is practiced as a religious and cultural tradition too. The cosmetic shops and earring kiosks use hand-powered earring guns or needles to pierce ears. Plastic surgeons are many a times requested to pierce a virgin ear lobule, or they have to pierce it after repair of split ear or a post traumatic avulsed lobule. With increasing fashion of multiple earringscartilage piercing is also becoming popular. After piercing the lobule, some stent is required to place in the hole to maintain its patency for few weeks... περισσότερα »
Eyelid swelling : Schwannoma of upper eyelid
Schwannoma of upper eyelid: A rare differential diagnosis of eyelid swellings: *Surendra B Patil, Satish M Kale, Sumeet Jaiswal, Nishant Khare* Indian Journal of Plastic Surgery 2010 43(2):213-215 Schwannoma is a relatively rare benign tumour of peripheral nerve origin. The occurrence of Schwannoma in eyelid is extremely rare. As per our knowledge, only 11 such cases have been reported in the literature so far. We present a case of a 40-year-old man who presented to us with a 2-year history of slowly enlarging, painless mass in his left upper lid with resultant progressive ptosi... περισσότερα »
Lip sparing mandibulotomy
Lip sparing mandibulotomy: avoiding morbidity: Within head and neck cancer surgery, access to the oropharynx will sometimes necessitate a mandibulotomy with a lip split. Different lip incisions have been described over the years in an attempt to reduce the morbidity of lip scarring but patients are often still left with unsatisfying results which only serves as a reminder of their past illness. Furthermore, by avoiding a lip split the integrity of the orbicularis oris sphincter is preserved and therefore function not compromised.
3D computer planning and additive manufactured surgical guides for fibula free flaps
Experiences of setting up an ‘in house’ service to provide 3D computer planning and additive manufactured surgical guides for fibula free flaps: Introduction: The use of the fibula osseo-cutaneous free flap to reconstruct the maxilla and mandible is well recognised and reliable. Harvesting the bone does not present any significant challenges, however, exact contouring of the fibula bone to the resection defect can be time consuming and always possesses the small risk of devitalising the harvested bone. *Fibula free flap*: a new method of mandible reconstruction. DA Hidalgo - ... περισσότερα »
Photochemical internalisation of bleomycin with TPCS2a in patients with solid malignancies
Photochemical internalisation of bleomycin with TPCS2a in patients with solid malignancies: phase I results and de-escalation of dose extension: Introduction: Photochemical internalisation (PCI study) is a promising intervention in the management of complex cancers of the head and neck. The results of phase I and the extension of the study with de-escalation of dose are included. [PDF] από researchgate.net Disulfonated tetraphenyl chlorin (TPCS 2a), a novel photosensitizer developed for clinical utilization of *photochemical internalization* K Berg, S Nordstrand, PK Selbo, DTT T...περισσότερα »
Indian Journal of Plastic Surgery
Standardize sub-speciality training to survive as a super-speciality *Surajit Bhattacharya* Indian Journal of Plastic Surgery 2010 43(2):131-132 Cheyyur Ramaswamy Sundararajan *KS Shekar, BA Anantharam* Indian Journal of Plastic Surgery 2010 43(2):133-134 Detail microscopic analysis of deep fascia of lower limb and its surgical implication *Visweswar Bhattacharya, Partha Sarathi Barooah, Tapas Chandra Nag, Gaurab Ranjan Chaudhuri, Siddhartha Bhattacharya* Indian Journal of Plastic Surgery 2010 43(2):135-140 Background: The knowledge regarding the structural details of deep fascia r...περισσότερα »
Calf perforator flaps for oral cavity reconstruction
Calf perforator flaps: first choice for oral cavity reconstruction: Introduction: Calf perforator flaps are emerging as a popular choice in H&N reconstruction due to their favourable donor site morbidity. There are multiple source vessels in this region – the medial sural artery (MSAP) flap is the most commonly used. We document our clinical experience using calf perforator flaps in oral cavity reconstruction. In addition, we performed a cadaveric dissection study to determine predictability of perforator topography. Anatomic basis of the gastrocnemius *perforator*-based *f... περισσότερα »
Threatened carotid blowout syndrome
Threatened carotid blowout syndrome: are endovascular covered stents neurologically safe and do they prevent catastrophic haemorrhage?: Aims: Traditional management of carotid blowout syndrome (CBS) is associated with high incidence of recurrent bleeding and neurological morbidity. Endovascular stents have an established role in the management of acute CBS but their role in pre-emptive management of a threatened carotid axis is controversial. We aimed to assess the safety and efficacy of carotid stents in threatened CBS. [PDF] από journalagent.com [PDF] *Carotid blowout syndrom...περισσότερα »
3D CT reconstruction in aiding the surgical management of Eagle's syndrome
The use of 3D CT reconstruction in aiding the surgical management of Eagle's syndrome: Introduction: Eagle's (or stylohyoid) syndrome describes a series of symptoms resulting from the elongation of the styloid process. For surgical management, a styloidectomy can be performed using either the intraoral transpharyngeal) or extraoral approach. Eagle introduced the intraoral transpharyngeal approach which has the advantage of avoiding an external scar and damage to the facial nerve. However, this method was discouraged due to poor visualisation and the risk of injury to major vessels.
Live electronic database for non melanoma skin cancer
How we do it: the introduction of a live electronic database for non melanoma skin cancer in a Maxillofacial Unit: Aims: Minimum Dataset collection in all aspects of surgery is challenging for both surgeons and clinicians alike. Although increasing in pace, the conversion from paper data collection (PDC) to Electronic Data Capture (EDC) within surgical practice has generally been a slow progression. We review the implementation of live EDC for non-melanoma skin cancer (NMSC) data collection in our practice. [HTML] από jamanetwork.com [HTML] Basal cell *skin carcinoma *and other...περισσότερα »
Minimizing revision rates with the “Π” technique for bilateral vocal fold immobility: A new technique combining carbon dioxide and diode laser
Abstract Background For more than 25 years, posterior laser transverse cordotomy has been generally considered the ideal endoscopic minimally invasive procedure of choice for bilateral vocal fold immobility. The main drawback of this procedure, when compared to more aggressive “glottic aperture improvement” operations, is the high revision rates, caused by granulations, adhesion, and scar, for …
Improving patient outcomes through multidisciplinary treatment planning conference
ABSTRACT Background The purpose of this study was for us to determine National Comprehensive Cancer Network (NCCN) guideline-compliance of multidisciplinary conference (MDC) recommendations and actual treatment received, and to determine this impact on patient outcomes. Methods We conducted a retrospective review of patients presented at MDC between January 1, 2006, and December 31, 2006, with …
ABCLOVE: Voice therapy outcomes for patients with head and neck cancer
Abstract Background Dysphonia related to head and neck cancer is unique, and demands treatment tailored to its unique pathology. Activate exercises, breathing, counseling, laryngeal manipulation, oral resonance, vocal exercises, and elimination of habits (ABCLOVE) is an 8-week multimodality voice therapy program addressing vocal rehabilitation specifically for patients with head and neck cancer. Methods Twenty-nine patients …
Emerging strategies for managing differentiated thyroid cancers refractory to radioiodine
Abstract Efficient treatment of radio refractory thyroid cancer is still a major challenge. The recent identification of genetic and epigenetic alterations present in almost all differentiated tumors has revealed novel molecular targets, which can hopefully be exploited to create new treatments for these tumors. This review looks briefly at some of the innovative strategies currently …
Docetaxel plus androgen deprivation withdrawal may restore sensitivity to luteinizing hormone-releasing hormone analog therapy in castration-resistant prostate cancer patients
from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1UYw825 via IFTTT
Unter Assistenzärzten grassiert die Depression
Bis zu 40 % Betroffene Ein erheblicher Anteil von Ärzten in der Weiterbildung plagt sich mit Depressionen herum. In den vergangenen Jahren ist die Lage nicht besser geworden, im Gegenteil – der Anteil Betroffener steigt. from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1QVCVsZ via IFTTT
Long-term outcomes of tyrosine kinase inhibitor discontinuation in patients with metastatic renal cell carcinoma
Abstract Purpose The purpose of the current study was to evaluate the clinical outcomes of patients with metastatic renal cell carcinoma (mRCC) who interrupted vascular endothelial growth factor receptor tyrosine kinase inhibitor (VEGFR–TKI) therapy. Methods A retrospective analysis of medical records was performed on all patients with mRCC treated with VEGFR–TKIs between January 2008 and …
A pharmacokinetic analysis of cisplatin and 5-fluorouracil in a patient with esophageal cancer on peritoneal dialysis
Abstract Background Very little is known about the pharmacokinetics of chemotherapeutic agents in patients also being treated with continuous ambulatory peritoneal dialysis. We sought to evaluate the pharmacokinetics of cisplatin and 5-fluorouracil in plasma and peritoneal dialysate in a patient being treated for esophageal adenocarcinoma. Methods A single patient with esophageal adenocarcinoma and on peritoneal …
Probing the characteristics of potential energy surfaces
The potential energy surface of multi-atomic systems encodes important aspects such as thermodynamic and dynamic properties or the equilibrium geometries. Collections of low-energy minima and the reaction pathways that connect the minima with each other can be key elements in the study of potential energy surfaces and their properties. The extension of the minima hopping …
Comparative effectiveness of fungicidal vs. fungistatic therapies for the treatment of paediatric candidaemia
Summary Adult data suggest that echinocandins for treatment of candidaemia are associated with decreased mortality, attributed to their fungicidal activity. There are limited data comparing antifungals in children. We compared 30-day all-cause mortality among paediatric candidaemia patients treated with fungicidal vs. fungistatic agents. All inpatients (>6 months and <19 years of age) with candidaemia between …
Unusual complications following thyroidectomy and parathyroidectomy
Unusual complications following thyroidectomy and parathyroidectomy: Introduction: Well known postoperative complications after thyroidectomy are haemorrhage, recurrent laryngeal nerve palsy and hypoparathyroidism when total thyroidectomy is the preferred treatment for thyroid cancer, multinodular goitre and Graves disease. Hence surgeons choose to perform hemithyroidectomy for benign thyroid disease to reduce the incidence of these complications. [HTML] από jamanetwork.com [HTML] Assessment *of *the morbidity and *complications of *total *thyroidectomy* N Bhattacharyya, MP Fri... περισσότερα »
CT imaging of the facial skeleton in trauma
Is CT imaging of the facial skeleton in trauma inadequate? How can inadequacies be overcome?: Introduction: There are 180,000 serious facial injuries annually, many of which form part of polytrauma. Computed tomography (CT) plays an important role in the initial imaging of these patients due to potential C-spine and head injuries. Scanning protocols do not demonstrate the entire facial skeleton in all cases. Further imaging is necessary if injuries cannot be excluded clinically. Structural pillars of the *facial skeleton*: an approach to the management of Le Fort fractures PN M... περισσότερα »
Periorbital necrotising fasciitis
Management, reconstruction and rehabilitation of a periorbital necrotising fasciitis: Necrotising fasciitis (NF) is a relatively uncommon but serious condition with a real risk of death. It is characterised by a rapidly progressing necrotising infection of fascial layers. It is commonly associated with a Group A streptococcal infection. Cases affecting the face are less common due to its superior blood supply. Periorbital NF can result in blindness and morbidity associated with facial cosmetic defects. However, if cases are managed early enough with adequate, urgent surgical debride... περισσότερα »
Oral Ulceration with Bone Sequestration
Systematic Review of via ScienceDirect Publication: Journal of Cranio-Maxillofacial Surgery Publication date: Available online 22 December 2015 *Source:*Journal of Cranio-Maxillofacial Surgery Author(s): Benjamin Palla, Egon Burian, John Richard Klecker, Riham Fliefel, Sven Otto BackgroundThis article represents the first systematic review entirely dedicated toward a disease called oral ulceration with bone sequestration (OUBS). We performed this review in order to further define and outline this disease. A secondary interest was to recognize the prevalence and importance of OUBS in r... περισσότερα »
Assisted mandibular or maxillary reconstruction with free flaps containing the lateral scapular border
Iterations of computer- and template assisted mandibular or maxillary reconstruction with free flaps containing the lateral scapular border – evolution of a biplanar plug-on cutting guide via ScienceDirect Publication: Journal of Cranio-Maxillofacial Surgery Publication date: Available online 21 December 2015 *Source:*Journal of Cranio-Maxillofacial Surgery Author(s): Carl-Peter Cornelius, Goetz Andreas Giessler, Frank Wilde, Marc Christian Metzger, Gerson Mast, Florian Andreas Probst BackgroundComputer-assisted planning and intraoperative implementation using templates have become appr...περισσότερα »
Injured condylar cartilage leads to traumatic temporomandibular joint ankylosis
Injured condylar cartilage leads to traumatic temporomandibular joint ankylosis via ScienceDirect Publication: Journal of Cranio-Maxillofacial Surgery Publication date: Available online 21 December 2015 *Source:*Journal of Cranio-Maxillofacial Surgery Author(s): Jiewen Dai, Ningjuan Ouyang, Xiaofang Zhu, Li Huang, Guofang Shen PurposeThe exact mechanisms of traumatic temporomandibular joint ankylosis (TTMJA) are largely unknown. In this study, we explore the role of injured condylar cartilage in the development of TTMJA.Material and MethodsOne-month-old male mice were divided into two g...περισσότερα »
Free flaps in the elderly
Free flaps in the elderly: does age make a difference to outcome?: Introduction/aims: Vascularised free flaps are now the mainstay solution for reconstructing oropharyngeal defects following oncologic resections. Concerns such as donor site morbidity, flap failure and systemic complications may be more pronounced in elderly patients with limited physiologic reserve and more co-morbidities, but it is unclear to what extent these concerns are justified. *Free flaps *in the *elderly*. LR Chick, RL Walton, W Reus, L Colen… - Plastic and …, 1992 - journals.lww.com TABLE I Preoperati... περισσότερα »
A robust genomic signature to predict recurrence in oral squamous cell carcinoma (OSCC)
Integration of multiple microarray datasets to generate a robust genomic signature to predict recurrence in oral squamous cell carcinoma (OSCC): Introduction: Accurate early prediction of recurrence in OSCC could be a powerful aid in focussing surveillance on appropriate patient groups and might also indicate the need for adjuvant therapy. The aim of this study was to determine a gene signature small enough to have clinical utility and that could reliably predict metastasis in OSCC. Correlation of gene methylation in surgical margin imprints with locoregional *recurrence *in he... περισσότερα »
Rapid prototype assisted orbital reconstruction
Rapid prototype assisted orbital reconstruction: a prospective trial: Introduction: Orbital fractures represent a significant percentage of midface trauma presentations. The aim of surgical management is to reconstruct the orbit as close to pre-morbid contour and volume in order to achieve optimum function and cosmesis. This is often challenging as visualization of the bony defect is difficult due to limited surgical access. Rapid prototyping uses a 3D printer to construct a model from CT imaging within a very short period of time. This paper seeks to evaluate the rapid prototyping ... περισσότερα »
Subjective facial disfigurement following maxillofacial injury
The psychological impact of subjective facial disfigurement following maxillofacial injury: Introduction: This qualitative research investigated male maxillofacial injury patients who sustained a subjective facial disfigurement following assault. The study offers an original contribution to the psychological literature surrounding assault and facial injury, and identifies areas for psychological support to be introduced to maxillofacial care pathways. [PDF] από nepjol.info Assessing psychological consequences *following maxillofacial trauma *using DASS scale–our experience PK P... περισσότερα »
Non-melanomatous facial skin cancers
Audit of all surgically treated non-melanomatous facial skin cancers in a single Maxillofacial Unit, 2006 to 2014: Introduction: We describe a prospective audit of all non-melanomatous, cutaneous lesions of the face neck and scalp in patients treated in Ninewells Hospital Maxillofacial Unit from August 2006 to December 2014. Clearance rates were compared to national guidelines. Data on tumour subtypes and size were analysed individually. Further information on aesthetic outcomes and incidence of new lesions at follow up was also obtained. Treatment of *Non*-*Melanomatous Skin C... περισσότερα »
The evolution of customised titanium reconstruction of post-traumatic orbital wall defects
The evolution of customised titanium reconstruction of post-traumatic orbital wall defects: an 11 year experience: Introduction: There is little doubt that the management of orbital wall fractures has created much debate over the years. The decision to treat surgically or not, the choice of surgical approach and material of choice have all been fiercely debated. The use of high-resolution computer tomography (CT) and the ability to view scans in three-dimensions has revolutionised how we manage post-traumatic orbital defects. In combination with rapid prototype models from CT data m... περισσότερα »
Multiple non-contiguous defects in an isolated orbital floor fracture
Multiple non-contiguous defects in an isolated orbital floor fracture: a case report: Introduction: Current classifications of orbital floor fractures group cases according to the size of defect, number of walls involved and the presence/absence of soft tissue herniation. This case represents a deviation from the usual classification of isolated orbital floor fractures. A review of the literature using MEDLINE failed to identify any previous reports of non-contiguous multiple defects within a single orbital floor.
Palate re-repair for Velopharyngeal Dysfunction in the cleft palate patient
Outcome of palate re-repair for Velopharyngeal Dysfunction in the cleft palate patient: Introduction: Palate re-repair is an accepted treatment for Velopharyngeal Dysfunction (VPD). Previously published literature suggests that despite being technically demanding, palate re-repair is an effective and physiologically superior procedure to pharyngoplasty alone and can achieve greater than 82% improvements in speech outcomes in the cleft palate patient with VPD. This aim of this study was to review the results of the first 53 consecutive cases of palate re-repair by a single cleft surg... περισσότερα »
Cholesterol granuloma of a Haller cell associated with unilateral exophthalmos and diplopia
Cholesterol granuloma of a Haller cell associated with unilateral exophthalmos and diplopia: Cholesterol granuloma is rare in the paranasal sinuses. We present what is to our knowledge the first case of cholesterol granuloma of a Haller cell associated with unilateral exophthalmos and diplopia in a 55-year-old man.
The standard and alternative periodic leg movement during sleep indices for restless legs syndrome
Diagnostic accuracy of via Sleep Medicine [image: S13899457.gif] Publication date: Available online 18 December 2015 *Source:*Sleep Medicine Author(s): Raffaele Ferri, Francesco Rundo, Marco Zucconi, Mauro Manconi, Debora Aricò, Oliviero Bruni, Luigi Ferini-Strambi, Stephany Fulda ObjectiveTo evaluate the diagnostic accuracy of the standard periodic leg movement during sleep (PLMS) index, a recently introduced alternative one, and the periodicity index (PI) for restless legs syndrome (RLS).Subjects and methodsA total of 107 patients with RLS were retrospectively identified and inclu... περισσότερα »
Nasal Expiratory Positive Airway Pressure Devices (Provent) for OSA
Nasal Expiratory Positive Airway Pressure Devices (Provent) for OSA: A Systematic Review and Meta-Analysis: Objective. To quantify the effectiveness of nasal expiratory positive airway pressure (nasal EPAP) devices or Provent as treatment for obstructive sleep apnea (OSA). Methods. PubMed and six other databases were searched through November 15, 2015, without language limitations. Results. Eighteen studies (920 patients) were included. Pre- and post-nasal EPAP means ± standard deviations (M ± SD) for apnea-hypopnea index (AHI) in 345 patients decreased from to events/hr (relative r...περισσότερα »
Multiscale entropic assessment of autonomic dysfunction in patients with obstructive sleep apnea and therapeutic impact of continuous positive airway pressure treatment
Multiscale entropic assessment of autonomic dysfunction in patients with obstructive sleep apnea and therapeutic impact of continuous positive airway pressure treatment: • Differences in heart rate variability between early and late phases of sleep reflect nocturnal changes in autonomic function.• Multiscale entropy identifies changes in heart rate variability that are severity dependent.• Parasympathetic tone remarkably decreases in severe obstructive sleep apnea (OSA) patients as they shift from early to late phases of sleep.• Autonomic function in OSA patients with continuous pos... περισσότερα »
ABCLOVE: Voice therapy outcomes for patients with head and neck cancer
ABCLOVE: Voice therapy outcomes for patients with head and neck cancer: Abstract Background Dysphonia related to head and neck cancer is unique, and demands treatment tailored to its unique pathology. Activate exercises, breathing, counseling, laryngeal manipulation, oral resonance, vocal exercises, and elimination of habits (ABCLOVE) is an 8-week multimodality voice therapy program addressing vocal rehabilitation specifically for patients with head and neck cancer. Methods Twenty-nine patients with a history of head and neck cancer were enrolled in the ABCLOVE program and outcomes ... περισσότερα »
Improving patient outcomes through multidisciplinary treatment planning conference
Improving patient outcomes through multidisciplinary treatment planning conference: ABSTRACT Background The purpose of this study was for us to determine National Comprehensive Cancer Network (NCCN) guideline-compliance of multidisciplinary conference (MDC) recommendations and actual treatment received, and to determine this impact on patient outcomes. Methods We conducted a retrospective review of patients presented at MDC between January 1, 2006, and December 31, 2006, with previously untreated incident cancers. Results We identified 232 patients, for whom MDC recommendations were... περισσότερα »
Minimizing revision rates with the “Π” technique for bilateral vocal fold immobility: A new technique combining carbon dioxide and diode laser
Minimizing revision rates with the “Π” technique for bilateral vocal fold immobility: A new technique combining carbon dioxide and diode laser: Abstract Background For more than 25 years, posterior laser transverse cordotomy has been generally considered the ideal endoscopic minimally invasive procedure of choice for bilateral vocal fold immobility. The main drawback of this procedure, when compared to more aggressive “glottic aperture improvement” operations, is the high revision rates, caused by granulations, adhesion, and scar, for example. Methods We describe a technique using a...περισσότερα »
Vocalic correlates of pitch in whispered versus normal speech
Vocalic correlates of pitch in whispered versus normal speech: In whispered speech, the fundamental frequency is absent as a main cue to pitch. This study investigated how different pitch targets can acoustically be coded in whispered relative to normal speech. Secondary acoustic correlates that are found in normal speech may be preserved in whisper. Alternatively, whispering speakers may provide compensatory information. Compared to earlier studies, a more comprehensive set of acoustic correlates (duration, intensity, formants, center-of-gravity, spectral balance) and a larger set... περισσότερα »
Context effects on second-language learning of tonal contrasts
Context effects on second-language learning of tonal contrasts: Studies of lexical tonelearning generally focus on monosyllabic contexts, while reports of phonetic learning benefits associated with input variability are based largely on experienced learners. This study trained inexperienced learners on Mandarin tonal contrasts to test two hypotheses regarding the influence of context and variability on tonelearning. The first hypothesis was that increased phonetic variability of tones in disyllabic contexts makes initial tonelearning more challenging in disyllabic than monosyllabic... περισσότερα »
fMRI as a Preimplant Objective Tool to Predict Postimplant Oral Language Outcomes in Children with Cochlear Implants.
fMRI as a Preimplant Objective Tool to Predict Postimplant Oral Language Outcomes in Children with Cochlear Implants.: Objectives: Despite the positive effects of cochlear implantation, postimplant variability in speech perception and oral language outcomes is still difficult to predict. The aim of this study was to identify neuroimaging biomarkers of postimplant speech perception and oral language performance in children with hearing loss who receive a cochlear implant. The authors hypothesized positive correlations between blood oxygen level-dependent functional magnetic resonance... περισσότερα »
Can Tinnitus Go Away
Can Tinnitus Go Away: If you have tinnitus, you may want nothing more than for your hearing condition to go away. Tinnitus is sometimes confused with hearing loss, but it is not related to loss of hearing. Instead, it is most aptly described as a ringing sound in the ears. People who have tinnitus may describe the sound in different ways, and it may not always be heard as a ring. For example, it may sound like a hiss, a chirp, a buzz, a whistle or other types of sounds. These sounds may be continuous or intermittent, and they may seem to be very loud or soft. If you have this condi... περισσότερα »
Somatic memory and gain increase as preconditions for tinnitus
: insights from congenital deafness via Hearing Research Publication date: Available online 21 December 2015 *Source:*Hearing Research Author(s): Jos J. Eggermont, Andrej Kral Tinnitus is the conscious perception of sound heard in the absence of physical sound sources internal or external to the body. The characterization of tinnitus by its spectrum reflects the missing frequencies originally represented in the hearing loss, i.e., partially or completely deafferented, region. The tinnitus percept, despite a total hearing loss, may thus be dependent on the persisting existence of a som...περισσότερα »
Dehydration effects of a V2 antagonist on endolymphatic hydrops
in guinea pigs via Hearing Research Publication date: Available online 21 December 2015 *Source:*Hearing Research Author(s): Naoya Egami, Akinobu Kakigi, Taizo Takeda, Tatsuya Yamasoba We investigated the influence of vasopressin type 2 receptor antagonist (OPC-41061; Tolvaptan) on experimentally induced endolymphatic hydrops (EH) in guinea pigs. In the first series, the endolymphatic sac (ES) of the left ear of all animals was electrocauterized. Four weeks after surgery, the animals were allocated to four groups: three systemic applications groups (saline, OPC 10 and 100 mg/kg) and a...περισσότερα »
Elicitation of the Acoustic Change Complex to Long-Duration Speech Stimuli in Four-Month-Old Infants
Elicitation of the Acoustic Change Complex to Long-Duration Speech Stimuli in Four-Month-Old Infants: The acoustic change complex (ACC) is an auditory-evoked potential elicited to changes within an ongoing stimulus that indicates discrimination at the level of the auditory cortex. Only a few studies to date have attempted to record ACCs in young infants. The purpose of the present study was to investigate the elicitation of ACCs to long-duration speech stimuli in English-learning 4-month-old infants. ACCs were elicited to consonant contrasts made up of two concatenated speech tokens...περισσότερα »
Supraglottoplasty for laryngomalacia with obstructive sleep apnea
Supraglottoplasty for laryngomalacia with obstructive sleep apnea: A systematic review and meta-analysis: Objectives/Hypothesis To determine if apnea-hypopnea index (AHI) and lowest oxygen saturation (LSAT) improve following isolated supraglottoplasty for laryngomalacia with obstructive sleep apnea (OSA) in children. Study Design Systematic review and meta-analysis. Methods Nine databases, including PubMed/MEDLINE, were searched through September 30, 2015. Results A total of 517 studies were screened; 57 were reviewed; and 13 met criteria. One hundred thirty-eight patients were inclu... περισσότερα »
Orbit fractures: Identifying patient factors indicating high risk for ocular and periocular injury
Orbit fractures: Identifying patient factors indicating high risk for ocular and periocular injury: Objectives/Hypothesis Maxillofacial trauma frequently involves the bony orbit that surrounds the ocular globe. Concomitant globe injury is a concern whenever orbit trauma occurs and in severe cases can occasionally result in vision loss. The mechanism of injury, physical exam findings, and radiographic imaging can provide useful information concerning the severity of the injury and concerns for vision loss. Using these three tools, it is hypothesized that the patient's history, physi... περισσότερα »
Segmental tracheal reconstruction by 3D-printed scaffold
Segmental tracheal reconstruction by 3D-printed scaffold: Pivotal role of asymmetrically porous membrane: Objectives/Hypothesis Three-dimensional (3D) printed scaffold for tracheal reconstruction can substitute the conventional treatment of tracheal stenosis. This study investigated the survival outcomes of segmental tracheal reconstruction using 3D printed polycaprolactone (PCL) scaffold with or without asymmetrically porous membrane in rabbit animal model. Study Design Animal study. Methods Six mature New Zealand white rabbits were categorized into two groups (three animals for ea... περισσότερα »
Lemierre syndrome is a complication of oropharyngeal infection and consists of a combination of internal jugular vein septic thrombophlebitis with septicaemia and distant septic emboli (mainly in the lungs)
Atypical Lemierre syndrome via European Annals of Otorhinolaryngology, Head and Neck Diseases Publication date: Available online 21 December 2015 *Source:*European Annals of Otorhinolaryngology, Head and Neck Diseases Author(s): M. Risoud, G. Mortuaire, D. Chevalier, B. Rysman IntroductionLemierre syndrome is a complication of oropharyngeal infection and consists of a combination of internal jugular vein septic thrombophlebitis with septicaemia and distant septic emboli (mainly in the lungs). We describe an atypical case with facial vein and anterior jugular vein thrombophlebitis.Case s... περισσότερα »
Excitation Patterns of Standard and Steered Partial Tripolar Stimuli in Cochlear Implants
Excitation Patterns of Standard and Steered Partial Tripolar Stimuli in Cochlear Implants: AbstractCurrent steering in partial tripolar (pTP) mode has been shown to improve pitch perception and spectral resolution with cochlear implants (CIs). In this mode, a fraction (*σ*) of the main electrode current is returned within the cochlea and steered between the basal and apical flanking electrodes (with a proportion of *α* and 1 − *α*, respectively). Pitch generally decreases when *α* increases from 0 to 1, although the salience of pitch change varies across CI users. This study aimed ... περισσότερα »
Selective Inner Hair Cell Dysfunction in Chinchillas Impairs Hearing-in-Noise in the Absence of Outer Hair Cell Loss
Selective Inner Hair Cell Dysfunction in Chinchillas Impairs Hearing-in-Noise in the Absence of Outer Hair Cell Loss: AbstractPoorer hearing in the presence of background noise is a significant problem for the hearing impaired. Ototoxic drugs, ageing, and noise exposure can damage the sensory hair cells of the inner ear that are essential for normal hearing sensitivity. The relationship between outer hair cell (OHC) loss and progressively poorer hearing sensitivity in quiet or in competing background noise is supported by a number of human and animal studies. In contrast, the effec... περισσότερα »
Increased Spontaneous Otoacoustic Emissions with a Detached Tectorial Membrane
Increased Spontaneous Otoacoustic Emissions in Mice with a Detached Tectorial Membrane: AbstractMutations in genes encoding tectorial membrane (TM) proteins are a significant cause of human hereditary hearing loss (Hildebrand et al. 2011), and several mouse models have been developed to study the functional significance of this accessory structure in the mammalian cochlea. In this study, we use otoacoustic emissions (OAE), signals obtained from the ear canal that provide a measure of cochlear function, to characterize a mouse in which the TM is detached from the spiral limbus due t...περισσότερα »
Fluid loading in - saline versus hydroxyethyl starch (FLASH Trial)
Fluid loading in abdominal surgery - saline versus hydroxyethyl starch (FLASH Trial): study protocol for a randomized controlled trial: Background: Inappropriate fluid therapy during surgery is associated with significant morbidity and mortality. Few studies have examined the effects of particular types of fluids (crystalloid or colloid solutions) in surgical patients, especially with the goal of hemodynamic optimization. Isotonic saline is the most commonly used fluid worldwide but may be associated with potential nephrotoxicity. Hydroxyethyl starch (HES) solutions are widely used i... περισσότερα »
Oral versus intravenous antibiotic treatment for bone and joint infections
Oral versus intravenous antibiotic treatment for bone and joint infections (OVIVA): study protocol for a randomised controlled trial: Background: Bone and joint infection in adults arises most commonly as a complication of joint replacement surgery, fracture fixation and diabetic foot infection. The associated morbidity can be devastating to patients and costs the National Health Service an estimated £20,000 to £40,000 per patient.Current standard of care in most UK centres includes a prolonged course (4–6 weeks) of intravenous antibiotics supported, if available, by an outpatient pa... περισσότερα »
Editorial Board
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GvHD prophylaxis in non-haploidentical allogeneic peripheral blood stem cell transplantation: beyond the standard to prevent relapse in patients with high-risk chronic lymphoproliferative diseases?
from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1OkLxKR via IFTTT
Table of Contents
from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1NJ2sBs via IFTTT
A Randomized Controlled Trial of the Effectiveness of Traditional and Mobile Public Health Communications With Health Care Providers
Research Articles Janet Baseman, Debra Revere, Ian Painter, Mark Oberle, Jeffrey Duchin, Hanne Thiede, Randall Nett, Dorothy MacEachern, Andy Stergachis Disaster Medicine and Public Health Preparedness, FirstView Article(s), 10 pages Abstract from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1OIclzb via IFTTT
Somatic memory and gain increase as preconditions for tinnitus: insights from congenital deafness
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 55 δευτερόλεπτα
Publication date: Available online 21 December 2015 Source:Hearing Research Author(s): Jos J. Eggermont, Andrej Kral Tinnitus is the conscious perception of sound heard in the absence of physical sound sources internal or external to the body. The characterization of tinnitus by its spectrum reflects the missing frequencies originally represented in the hearing loss, i.e., partially […]
Biosynthesis of glycosaminoglycans: associated disorders and biochemical tests
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 55 δευτερόλεπτα
Abstract Glycosaminoglycans (GAG) are long, unbranched heteropolymers with repeating disaccharide units that make up the carbohydrate moiety of proteoglycans. Six distinct classes of GAGs are recognized. Their synthesis follows one of three biosynthetic pathways, depending on the type of oligosaccharide linker they contain. Chondroitin sulfate, dermatan sulfate, heparan sulfate, and heparin sulfate contain a common […]
Impact of age at onset and newborn screening on outcome in organic acidurias
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 55 δευτερόλεπτα
Abstract Background and aim To describe current diagnostic and therapeutic strategies in organic acidurias (OADs) and to evaluate their impact on the disease course allowing harmonisation. Methods Datasets of 567 OAD patients from the E-IMD registry were analysed. The sample includes patients with methylmalonic (MMA, n = 164), propionic (PA, n = 144) and isovaleric aciduria (IVA, n = 83), and […]
New circadian rhythms found in older people
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 55 δευτερόλεπτα
A study of thousands of genes in 146 human brains shows that older people lose some circadian rhythms but develop some new ones, providing insights that could help treat dementia. from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1QHSaaB via IFTTT
Prediction of long-term major events soon after a first ST-segment elevation myocardial infarction by cardiovascular magnetic resonance
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 55 δευτερόλεπτα
Publication date: Available online 21 December 2015 Source:European Journal of Radiology Author(s): Clara Bonanad, Jose V. Monmeneu, Maria P. Lopez-Lereu, Arantxa Hervas, Elena de Dios, Jose Gavara, Julio Nunez, Gema Minana, Oliver Husser, Ana Paya, Paolo Racugno, Sergio García-Blas, Francisco J. Chorro, Vicente Bodi BackgroundCardiovascular magnetic resonance (CMR) predicts combined clinical events in post-ST-segment elevation […]
Detection and size measurements of pulmonary nodules in ultra-low-dose CT with iterative reconstruction compared to low dose CT
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 55 δευτερόλεπτα
Publication date: Available online 21 December 2015 Source:European Journal of Radiology Author(s): Xin Sui, Felix G. Meinel, Wei Song, Xiaoli Xu, Wang Zixing, Wang Yuyan, Zhengyu Jin, Jiuhong Chen, Rozemarijn Vliegenthart, U. Joseph Schoepf BackgroundIn this study, the accuracy of ultra-low-dose computed tomography (CT) with iterative reconstruction (IR) for detection and measurement of pulmonary nodules […]
Editorial Board
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 55 δευτερόλεπτα
from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1NJ2vgz via IFTTT
GvHD prophylaxis in non-haploidentical allogeneic peripheral blood stem cell transplantation: beyond the standard to prevent relapse in patients with high-risk chronic lymphoproliferative diseases?
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 55 δευτερόλεπτα
from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1OkLxKR via IFTTT
Table of Contents
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 55 δευτερόλεπτα
from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1NJ2sBs via IFTTT
A Randomized Controlled Trial of the Effectiveness of Traditional and Mobile Public Health Communications With Health Care Providers
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 55 δευτερόλεπτα
Research Articles Janet Baseman, Debra Revere, Ian Painter, Mark Oberle, Jeffrey Duchin, Hanne Thiede, Randall Nett, Dorothy MacEachern, Andy Stergachis Disaster Medicine and Public Health Preparedness, FirstView Article(s), 10 pages Abstract from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1OIclzb via IFTTT
Table of Contents
from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1NJ2sBs via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1NJ2OI8 via IFTTT
A Randomized Controlled Trial of the Effectiveness of Traditional and Mobile Public Health Communications With Health Care Providers
Research Articles Janet Baseman, Debra Revere, Ian Painter, Mark Oberle, Jeffrey Duchin, Hanne Thiede, Randall Nett, Dorothy MacEachern, Andy Stergachis Disaster Medicine and Public Health Preparedness, FirstView Article(s), 10 pages Abstract [image: Facebook][image: Twitter][image: Mendeley][image: Email][image: More...] from #ORL-AlexandrosSfakianakis via simeraentaxei on Inoreader http://ift.tt/1OIclzb via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1NzYKMD via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via ... περισσότερα »
A Randomized Controlled Trial of the Effectiveness of Traditional and Mobile Public Health Communications With Health Care Providers
Research Articles Janet Baseman, Debra Revere, Ian Painter, Mark Oberle, Jeffrey Duchin, Hanne Thiede, Randall Nett, Dorothy MacEachern, Andy Stergachis Disaster Medicine and Public Health Preparedness, FirstView Article(s), 10 pages Abstract [image: Facebook][image: Twitter][image: Mendeley][image: Email][image: More...] from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1OIclzb via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1RCTk7p via IFTTT from #Med Blogs by Alexandros G.Sfakianakis vi... περισσότερα »
Injured condylar cartilage leads to traumatic temporomandibular joint ankylosis
Publication date: Available online 21 December 2015 *Source:*Journal of Cranio-Maxillofacial Surgery Author(s): Jiewen Dai, Ningjuan Ouyang, Xiaofang Zhu, Li Huang, Guofang Shen PurposeThe exact mechanisms of traumatic temporomandibular joint ankylosis (TTMJA) are largely unknown. In this study, we explore the role of injured condylar cartilage in the development of TTMJA.Material and MethodsOne-month-old male mice were divided into two groups. In group 1, condylar cartilage was partially removed in the right joint using a small scissors to induce ankylosis. In group 2, condylar cart...περισσότερα »
Systematic Review of Oral Ulceration with Bone Sequestration
Publication date: Available online 22 December 2015 *Source:*Journal of Cranio-Maxillofacial Surgery Author(s): Benjamin Palla, Egon Burian, John Richard Klecker, Riham Fliefel, Sven Otto BackgroundThis article represents the first systematic review entirely dedicated toward a disease called oral ulceration with bone sequestration (OUBS). We performed this review in order to further define and outline this disease. A secondary interest was to recognize the prevalence and importance of OUBS in relation to other oral disorders accompanied by ulceration and bone exposure.Material and m... περισσότερα »
Iterations of computer- and template assisted mandibular or maxillary reconstruction with free flaps containing the lateral scapular border – evolution of a biplanar plug-on cutting guide
Publication date: Available online 21 December 2015 *Source:*Journal of Cranio-Maxillofacial Surgery Author(s): Carl-Peter Cornelius, Goetz Andreas Giessler, Frank Wilde, Marc Christian Metzger, Gerson Mast, Florian Andreas Probst BackgroundComputer-assisted planning and intraoperative implementation using templates have become appreciated modalities in craniofacial reconstruction with fibula and DCIA flaps due to saving in operation time, improved accuracy of osteotomies and easy insetting. Up to now, a similar development for flaps from the subscapular vascular system, namely the ... περισσότερα »
Increased Spontaneous Otoacoustic Emissions in Mice with a Detached Tectorial Membrane
Abstract Mutations in genes encoding tectorial membrane (TM) proteins are a significant cause of human hereditary hearing loss (Hildebrand et al. 2011), and several mouse models have been developed to study the functional significance of this accessory structure in the mammalian cochlea. In this study, we use otoacoustic emissions (OAE), signals obtained from the ear canal that provide a measure of cochlear function, to characterize a mouse in which the TM is detached from the spiral limbus due to an absence of otoancorin (Otoa, Lukashkin et al. 2012). Our results demonstrate that ... περισσότερα »
Ungeschützter Geschlechtsverkehr bringt E. coli daher
Ursachenforschung Nach ungeschütztem Vaginalverkehr kann es zu einer Kolonisation der Vagina mit E. coli kommen. Dafür fanden sich Ursachen unterschiedlicher Art. from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1S7wGmX via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1RCSGqu via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1O5WL40 via IFTTT
Selective Inner Hair Cell Dysfunction in Chinchillas Impairs Hearing-in-Noise in the Absence of Outer Hair Cell Loss
Abstract Poorer hearing in the presence of background noise is a significant problem for the hearing impaired. Ototoxic drugs, ageing, and noise exposure can damage the sensory hair cells of the inner ear that are essential for normal hearing sensitivity. The relationship between outer hair cell (OHC) loss and progressively poorer hearing sensitivity in quiet or in competing background noise is supported by a number of human and animal studies. In contrast, the effect of moderate inner hair cell (IHC) loss or dysfunction shows almost no impact on behavioral measures of hearing sens... περισσότερα »
Excitation Patterns of Standard and Steered Partial Tripolar Stimuli in Cochlear Implants
Abstract Current steering in partial tripolar (pTP) mode has been shown to improve pitch perception and spectral resolution with cochlear implants (CIs). In this mode, a fraction (*σ*) of the main electrode current is returned within the cochlea and steered between the basal and apical flanking electrodes (with a proportion of *α* and 1 − *α*, respectively). Pitch generally decreases when *α* increases from 0 to 1, although the salience of pitch change varies across CI users. This study aimed to identify the mechanism of pitch changes with pTP-mode current steering and the factors ... περισσότερα »
Letter on the article “Head and neck sarcoma: Analysis of 29 cases”
Publication date: Available online 21 December 2015 *Source:*European Annals of Otorhinolaryngology, Head and Neck Diseases Author(s): M. Carifi, D. Dall'Olio from #ORL-AlexandrosSfakianakis via ola Kala on Inoreader http://ift.tt/1Jr1aJi via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1NzXXel via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1NJ2OrL via IFTTT
Injured condylar cartilage leads to traumatic temporomandibular joint ankylosis
Publication date: Available online 21 December 2015 *Source:*Journal of Cranio-Maxillofacial Surgery Author(s): Jiewen Dai, Ningjuan Ouyang, Xiaofang Zhu, Li Huang, Guofang Shen PurposeThe exact mechanisms of traumatic temporomandibular joint ankylosis (TTMJA) are largely unknown. In this study, we explore the role of injured condylar cartilage in the development of TTMJA.Material and MethodsOne-month-old male mice were divided into two groups. In group 1, condylar cartilage was partially removed in the right joint using a small scissors to induce ankylosis. In group 2, condylar cart...περισσότερα »
Atypical Lemierre syndrome
Publication date: Available online 21 December 2015 *Source:*European Annals of Otorhinolaryngology, Head and Neck Diseases Author(s): M. Risoud, G. Mortuaire, D. Chevalier, B. Rysman IntroductionLemierre syndrome is a complication of oropharyngeal infection and consists of a combination of internal jugular vein septic thrombophlebitis with septicaemia and distant septic emboli (mainly in the lungs). We describe an atypical case with facial vein and anterior jugular vein thrombophlebitis.Case summaryA 34-year-old woman attended the emergency room with tonsillitis, left head and neck ...περισσότερα »
Iterations of computer- and template assisted mandibular or maxillary reconstruction with free flaps containing the lateral scapular border – evolution of a biplanar plug-on cutting guide
Publication date: Available online 21 December 2015 *Source:*Journal of Cranio-Maxillofacial Surgery Author(s): Carl-Peter Cornelius, Goetz Andreas Giessler, Frank Wilde, Marc Christian Metzger, Gerson Mast, Florian Andreas Probst BackgroundComputer-assisted planning and intraoperative implementation using templates have become appreciated modalities in craniofacial reconstruction with fibula and DCIA flaps due to saving in operation time, improved accuracy of osteotomies and easy insetting. Up to now, a similar development for flaps from the subscapular vascular system, namely the ... περισσότερα »
A Randomized Controlled Trial of the Effectiveness of Traditional and Mobile Public Health Communications With Health Care Providers
Research Articles Janet Baseman, Debra Revere, Ian Painter, Mark Oberle, Jeffrey Duchin, Hanne Thiede, Randall Nett, Dorothy MacEachern, Andy Stergachis Disaster Medicine and Public Health Preparedness, FirstView Article(s), 10 pages Abstract [image: Facebook][image: Twitter][image: Mendeley][image: Email][image: More...] from #ORL-AlexandrosSfakianakis via simeraentaxei on Inoreader http://ift.tt/1OIclzb via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1NzYKMD via IFTTT
A Randomized Controlled Trial of the Effectiveness of Traditional and Mobile Public Health Communications With Health Care Providers
Research Articles Janet Baseman, Debra Revere, Ian Painter, Mark Oberle, Jeffrey Duchin, Hanne Thiede, Randall Nett, Dorothy MacEachern, Andy Stergachis Disaster Medicine and Public Health Preparedness, FirstView Article(s), 10 pages Abstract [image: Facebook][image: Twitter][image: Mendeley][image: Email][image: More...] from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1OIclzb via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1RCTk7p via IFTTT
Injured condylar cartilage leads to traumatic temporomandibular joint ankylosis
Publication date: Available online 21 December 2015 *Source:*Journal of Cranio-Maxillofacial Surgery Author(s): Jiewen Dai, Ningjuan Ouyang, Xiaofang Zhu, Li Huang, Guofang Shen PurposeThe exact mechanisms of traumatic temporomandibular joint ankylosis (TTMJA) are largely unknown. In this study, we explore the role of injured condylar cartilage in the development of TTMJA.Material and MethodsOne-month-old male mice were divided into two groups. In group 1, condylar cartilage was partially removed in the right joint using a small scissors to induce ankylosis. In group 2, condylar cart...περισσότερα »
Systematic Review of Oral Ulceration with Bone Sequestration
Publication date: Available online 22 December 2015 *Source:*Journal of Cranio-Maxillofacial Surgery Author(s): Benjamin Palla, Egon Burian, John Richard Klecker, Riham Fliefel, Sven Otto BackgroundThis article represents the first systematic review entirely dedicated toward a disease called oral ulceration with bone sequestration (OUBS). We performed this review in order to further define and outline this disease. A secondary interest was to recognize the prevalence and importance of OUBS in relation to other oral disorders accompanied by ulceration and bone exposure.Material and m... περισσότερα »
Iterations of computer- and template assisted mandibular or maxillary reconstruction with free flaps containing the lateral scapular border – evolution of a biplanar plug-on cutting guide
Publication date: Available online 21 December 2015 *Source:*Journal of Cranio-Maxillofacial Surgery Author(s): Carl-Peter Cornelius, Goetz Andreas Giessler, Frank Wilde, Marc Christian Metzger, Gerson Mast, Florian Andreas Probst BackgroundComputer-assisted planning and intraoperative implementation using templates have become appreciated modalities in craniofacial reconstruction with fibula and DCIA flaps due to saving in operation time, improved accuracy of osteotomies and easy insetting. Up to now, a similar development for flaps from the subscapular vascular system, namely the ... περισσότερα »
Increased Spontaneous Otoacoustic Emissions in Mice with a Detached Tectorial Membrane
Abstract Mutations in genes encoding tectorial membrane (TM) proteins are a significant cause of human hereditary hearing loss (Hildebrand et al. 2011), and several mouse models have been developed to study the functional significance of this accessory structure in the mammalian cochlea. In this study, we use otoacoustic emissions (OAE), signals obtained from the ear canal that provide a measure of cochlear function, to characterize a mouse in which the TM is detached from the spiral limbus due to an absence of otoancorin (Otoa, Lukashkin et al. 2012). Our results demonstrate that ... περισσότερα »
Ungeschützter Geschlechtsverkehr bringt E. coli daher
Ursachenforschung Nach ungeschütztem Vaginalverkehr kann es zu einer Kolonisation der Vagina mit E. coli kommen. Dafür fanden sich Ursachen unterschiedlicher Art. from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1S7wGmX via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1RCSGqu via IFTTT
Selective Inner Hair Cell Dysfunction in Chinchillas Impairs Hearing-in-Noise in the Absence of Outer Hair Cell Loss
Abstract Poorer hearing in the presence of background noise is a significant problem for the hearing impaired. Ototoxic drugs, ageing, and noise exposure can damage the sensory hair cells of the inner ear that are essential for normal hearing sensitivity. The relationship between outer hair cell (OHC) loss and progressively poorer hearing sensitivity in quiet or in competing background noise is supported by a number of human and animal studies. In contrast, the effect of moderate inner hair cell (IHC) loss or dysfunction shows almost no impact on behavioral measures of hearing sens... περισσότερα »
Excitation Patterns of Standard and Steered Partial Tripolar Stimuli in Cochlear Implants
Abstract Current steering in partial tripolar (pTP) mode has been shown to improve pitch perception and spectral resolution with cochlear implants (CIs). In this mode, a fraction (*σ*) of the main electrode current is returned within the cochlea and steered between the basal and apical flanking electrodes (with a proportion of *α* and 1 − *α*, respectively). Pitch generally decreases when *α* increases from 0 to 1, although the salience of pitch change varies across CI users. This study aimed to identify the mechanism of pitch changes with pTP-mode current steering and the factors ... περισσότερα »
Letter on the article “Head and neck sarcoma: Analysis of 29 cases”
Publication date: Available online 21 December 2015 *Source:*European Annals of Otorhinolaryngology, Head and Neck Diseases Author(s): M. Carifi, D. Dall'Olio from #ORL-AlexandrosSfakianakis via ola Kala on Inoreader http://ift.tt/1Jr1aJi via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1NzXXel via IFTTT
Injured condylar cartilage leads to traumatic temporomandibular joint ankylosis
Publication date: Available online 21 December 2015 *Source:*Journal of Cranio-Maxillofacial Surgery Author(s): Jiewen Dai, Ningjuan Ouyang, Xiaofang Zhu, Li Huang, Guofang Shen PurposeThe exact mechanisms of traumatic temporomandibular joint ankylosis (TTMJA) are largely unknown. In this study, we explore the role of injured condylar cartilage in the development of TTMJA.Material and MethodsOne-month-old male mice were divided into two groups. In group 1, condylar cartilage was partially removed in the right joint using a small scissors to induce ankylosis. In group 2, condylar cart...περισσότερα »
Is there such a thing as a mechanical fall?
The American Journal of Emergency Medicine from Emergency Medicine via ola Kala on Inoreader http://ift.tt/1QI0WFu via IFTTT
Trends and outcomes of postpartum haemorrhage, 2003-2011
BMC Pregnancy and Childbirth from Emergency Medicine via ola Kala on Inoreader http://ift.tt/1U1UgzM via IFTTT
Pathophysiological effects of Cerastes cerastes and Vipera lebetina venoms: Immunoneutralization using anti-native and anti-60Co irradiated venoms
Biologicals from Emergency Medicine via ola Kala on Inoreader http://ift.tt/1QI0Tth via IFTTT
Differences by gender in completed suicides in a Mexican population: A psychological autopsy study
Journal of Forensic and Legal Medicine from Emergency Medicine via ola Kala on Inoreader http://ift.tt/1U1UdEe via IFTTT
Paracetamol as a toxic substance for children: aspects of legislation in selected countries
Journal of Occupational Medicine and Toxicology from Emergency Medicine via ola Kala on Inoreader http://ift.tt/1QI0W8x via IFTTT
Do spinal cord-injured individuals with stronger sense of coherence use different psychological defense styles?
Spinal Cord from Emergency Medicine via ola Kala on Inoreader http://ift.tt/1QI0TcL via IFTTT
Comparison of the fluid resuscitation rate with and without external pressure using two intraosseous infusion systems for adult emergencies, the citrin (comparison of intraosseous infusion systems in emergency medicine)-study
PLOS ONE from Emergency Medicine via ola Kala on Inoreader http://ift.tt/1QI0TcH via IFTTT
Predicting factors and risk stratification for return visits to the emergency department within 72 hours in pediatric patients
Pediatric Emergency Care from Emergency Medicine via ola Kala on Inoreader http://ift.tt/1QI0TcF via IFTTT
Emergency hysterectomy for uncontrolled postpartum hemorrhage may be averted through uterine balloon tamponade in Kenya and Senegal
International Journal of Gynecology & Obstetrics from Emergency Medicine via ola Kala on Inoreader http://ift.tt/1QI0SWl via IFTTT
What do EMS personnel think about domestic violence? An exploration of attitudes and experiences after participation in training
Journal of Forensic and Legal Medicine from Emergency Medicine via ola Kala on Inoreader http://ift.tt/1U1Ud73 via IFTTT
Predictors of acute renal failure during extracorporeal membrane oxygenation in pediatric patients after cardiac surgery
Artificial Organs from Emergency Medicine via ola Kala on Inoreader http://ift.tt/1U1UcQP via IFTTT
Evaluation of the GenoType® MTBDRsl assay in Korean patients with MDR or XDR tuberculosis
10.3109/23744235.2015.1125999<br>Hyun Yong Jeong from Infection via ola Kala on Inoreader http://ift.tt/1ImiYdI via IFTTT
Dermatophytosis in northern Africa
Summary Infections caused by dermatophytes are a global problem and a major public health burden in the world today. In Africa, especially in the northern geographical zone, dermatophytic infections are being reported at an alarming rate. This is mostly because of some local but unique cultural practices, socioeconomic and environmental conditions, lack of reliable diagnostic personnel and facilities and ineffective treatment. Interestingly, the pathogen spectrum and the clinical manifestation are most times different from what is seen in other continents. Several epidemiological ... περισσότερα »
Invasive pulmonary mycosis due to Chaetomium globosum with false-positive galactomannan test: a case report and literature review
[image: cover.gif?v=1&s=1293bca8a559e0d3aa21dc00] Summary In this case, the authors report *Chaetomium globosum* as a cause of invasive pulmonary infection in a patient with Wegener's granulomatosis. Fungal hyphae (KOH and Calcofluor) were seen on direct microscopy of lung biopsy sample and bronchoalveolar lavage (BAL) sample. *C. globosum* isolated on culture clinched the diagnosis of invasive pulmonary infection by *Chaetomium* spp. A positive galactomannan of serum and BAL was repeatedly seen and was utilised for follow-up and as prognostic marker in patient management. The pa... περισσότερα »
Thiamine antivitamins – an opportunity of therapy of fungal infections caused by Malassezia pachydermatis and Candida albicans
Summary Severe skin diseases and systemic fungaemia are caused by *Malassezia pachydermatis* and *Candida albicans* respectively. Antifungal therapies are less effective because of chronic character of infections and high percentage of relapses. Therefore, there is a great need to develop new strategies of antifungal therapies. We previously found that oxythiamine decreases proliferation of yeast (*Saccharomyces cerevisiae*), therefore we suggest that thiamine antivitamins can be considered as antifungal agents. The aim of this study was the comparison of thiamine antivitamins (ox...περισσότερα »
Fluorescent Pseudomonads in the Phyllosphere of Wheat: Potential Antagonists Against Fungal Phytopathogens
Abstract Fluorescent pseudomonads isolated from wheat leaves were characterized regarding their antagonistic potential and taxonomy in relation to protect crop plants from infestation by *Fusarium* and *Alternaria* fungi causing diseases in wheat. Using a dual culture assay, inhibition of fungal growth was found for 40 isolates of 175 fluorescent pseudomonads. Twenty-two of the antagonists were able to suppress strains of *Fusarium* as well as *Alternaria*. By means of real-time qPCR, the *phlD* gene encoding the antibiotic 2,4-diacetylphloroglucinol was detected in 20 isolates. On... περισσότερα »
Lytic Action of the Truncated yncE Gene in Escherichia coli
Abstract We recently found lytic action of the truncated *yncE* gene. When the truncated *yncE* gene of *Salmonella enterica* serovar Paratyphi A was expressed in *Escherichia coli* DH5α under the control of the Ara promoter, bacterial growth was markedly inhibited. In the present study, we characterized this lytic action. The N-terminal 103 aa of YncE, containing a signal peptide, was demonstrated to be essential for inhibition. Microscopic observation showed that the bacterial envelope of *E*. *coli* was damaged by the expression of truncated *yncE*, resulting in the release of ...περισσότερα »
Wenyingzhuangia aestuarii sp. nov., A Marine Bacterium of the Family Flavobacteriaceae Isolated from an Estuary
Abstract A Gram-negative, strictly aerobic, chemoheterotrophic, pale-yellow pigmented, non-motile, rod-shaped bacterial strain, designated MN1-138T, was isolated from water in the tidal zone at the estuary of Heita river, Iwate, Japan, using an in situ cultivation technique. Preliminary analysis based on the 16S rRNA gene sequence revealed that the novel isolate is affiliated with the family *Flavobacteriaceae* of the phylum *Bacteroidetes*, and the highest sequence similarities were found with the species *Wenyingzhuangia heitensis* H-MN17T (97.3 %). The DNA–DNA relatedness betwee... περισσότερα »
SDS-PAGE and Gel IEF: Tool for Differentiation of Methicillin-Resistant and Methicillin-Sensitive Strains of Staphylococcus aureus
Abstract The methicillin-resistant *Staphylococcus aureus* causes difficult-to-treat healthcare-associated infections in humans. For fast and effective selection of an appropriate antibiotic therapy, it is essential to have rapid and reliable methods for differentiation of methicillin-resistant *S. aureus* from less dangerous methicillin-sensitive *S. aureus.* There have been many methods for the identification of methicillin-resistant *S. aureus* described but none has been accepted as an international standard. The most commonly used techniques such as phenotyping and genotyping ... περισσότερα »
The burden of serious human fungal infections in Brazil
[image: cover.gif?v=1&s=1293bca8a559e0d3aa21dc00] Summary In Brazil, human fungal infections are prevalent, however, these conditions are not officially reportable diseases. To estimate the burden of serious fungal diseases in 1 year in Brazil, based on available data and published literature. Historical official data from fungal diseases were collected from Brazilian Unified Health System Informatics Department (DATASUS). For fungal diseases for which no official data were available, assumptions of frequencies were made by estimating based on published literature. The incidence ... περισσότερα »
Safety and efficacy of phage therapy via the intravenous route
Increasing development of antimicrobial resistance is driving a resurgence in interest in phage therapy: the use of bacteriophages to treat bacterial infections. As the lytic action of bacteriophages is unaffected by the antibiotic resistance status of their bacterial target it is thought that phage therapy may have considerable potential in the treatment of a wide range of topical and localized infections. As yet this interest has not extended to intravenous (IV) use, which is surprising given that the historical record shows that phages are likely to be safe and effective when d... περισσότερα »
Operational implementation and lessons learned from Haiti's first helicopter air ambulance
Injury from Emergency Medicine via ola Kala on Inoreader http://ift.tt/1U1UaIr via IFTTT
TRUST-tPA trial: Telemedicine for remote collaboration with urgentists for stroke-tPA treatment
Journal of Telemedicine and Telecare from Emergency Medicine via ola Kala on Inoreader http://ift.tt/1QI0VkK via IFTTT
Ethical and regulatory challenges in advancing prehospital research: focus on sepsis
The American Journal of Emergency Medicine from Emergency Medicine via ola Kala on Inoreader http://ift.tt/1U1UcA3 via IFTTT
Injured condylar cartilage leads to traumatic temporomandibular joint ankylosis
Publication date: Available online 21 December 2015 Source:Journal of Cranio-Maxillofacial Surgery Author(s): Jiewen Dai, Ningjuan Ouyang, Xiaofang Zhu, Li Huang, Guofang Shen PurposeThe exact mechanisms of traumatic temporomandibular joint ankylosis (TTMJA) are largely unknown. In this study, we explore the role of injured condylar cartilage in the development of TTMJA.Material and MethodsOne-month-old male mice were …
Systematic Review of Oral Ulceration with Bone Sequestration
Publication date: Available online 22 December 2015 Source:Journal of Cranio-Maxillofacial Surgery Author(s): Benjamin Palla, Egon Burian, John Richard Klecker, Riham Fliefel, Sven Otto BackgroundThis article represents the first systematic review entirely dedicated toward a disease called oral ulceration with bone sequestration (OUBS). We performed this review in order to further define and outline this disease. …
Iterations of computer- and template assisted mandibular or maxillary reconstruction with free flaps containing the lateral scapular border – evolution of a biplanar plug-on cutting guide
Publication date: Available online 21 December 2015 Source:Journal of Cranio-Maxillofacial Surgery Author(s): Carl-Peter Cornelius, Goetz Andreas Giessler, Frank Wilde, Marc Christian Metzger, Gerson Mast, Florian Andreas Probst BackgroundComputer-assisted planning and intraoperative implementation using templates have become appreciated modalities in craniofacial reconstruction with fibula and DCIA flaps due to saving in operation time, improved accuracy of …
Increased Spontaneous Otoacoustic Emissions in Mice with a Detached Tectorial Membrane
Abstract Mutations in genes encoding tectorial membrane (TM) proteins are a significant cause of human hereditary hearing loss (Hildebrand et al. 2011), and several mouse models have been developed to study the functional significance of this accessory structure in the mammalian cochlea. In this study, we use otoacoustic emissions (OAE), signals obtained from the ear …
Ungeschützter Geschlechtsverkehr bringt E. coli daher
Ursachenforschung Nach ungeschütztem Vaginalverkehr kann es zu einer Kolonisation der Vagina mit E. coli kommen. Dafür fanden sich Ursachen unterschiedlicher Art. from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1S7wGmX via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1RCSGqu via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader …
Selective Inner Hair Cell Dysfunction in Chinchillas Impairs Hearing-in-Noise in the Absence of Outer Hair Cell Loss
Abstract Poorer hearing in the presence of background noise is a significant problem for the hearing impaired. Ototoxic drugs, ageing, and noise exposure can damage the sensory hair cells of the inner ear that are essential for normal hearing sensitivity. The relationship between outer hair cell (OHC) loss and progressively poorer hearing sensitivity in quiet …
Excitation Patterns of Standard and Steered Partial Tripolar Stimuli in Cochlear Implants
Abstract Current steering in partial tripolar (pTP) mode has been shown to improve pitch perception and spectral resolution with cochlear implants (CIs). In this mode, a fraction (σ) of the main electrode current is returned within the cochlea and steered between the basal and apical flanking electrodes (with a proportion of α and 1 − α, respectively). …
Letter on the article “Head and neck sarcoma: Analysis of 29 cases”
Publication date: Available online 21 December 2015 Source:European Annals of Otorhinolaryngology, Head and Neck Diseases Author(s): M. Carifi, D. Dall’Olio from #ORL-AlexandrosSfakianakis via ola Kala on Inoreader http://ift.tt/1Jr1aJi via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1NzXXel via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader …
Injured condylar cartilage leads to traumatic temporomandibular joint ankylosis
Publication date: Available online 21 December 2015 Source:Journal of Cranio-Maxillofacial Surgery Author(s): Jiewen Dai, Ningjuan Ouyang, Xiaofang Zhu, Li Huang, Guofang Shen PurposeThe exact mechanisms of traumatic temporomandibular joint ankylosis (TTMJA) are largely unknown. In this study, we explore the role of injured condylar cartilage in the development of TTMJA.Material and MethodsOne-month-old male mice were …
Atypical Lemierre syndrome
Publication date: Available online 21 December 2015 Source:European Annals of Otorhinolaryngology, Head and Neck Diseases Author(s): M. Risoud, G. Mortuaire, D. Chevalier, B. Rysman IntroductionLemierre syndrome is a complication of oropharyngeal infection and consists of a combination of internal jugular vein septic thrombophlebitis with septicaemia and distant septic emboli (mainly in the lungs). We describe …
The Eosinophil in Infection
sfakianakismedicsστοORL ALLERGY AESTHETICS ANATOMY Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Abstract First described by Paul Ehrlich in 1879, who noted its characteristic staining by acidophilic dyes, for many years, the eosinophil was considered to be an end-effector cell associated with helminth infections and a cause of tissue damage. Over the past 30 years, research has helped to elucidate the complexity of the eosinophil’s function and […]
Inter-comparison of dynamic models for radionuclide transfer to marine biota in a Fukushima accident scenario
Publication date: March 2016 *Source:*Journal of Environmental Radioactivity, Volume 153 Author(s): J. Vives i Batlle, N.A. Beresford, K. Beaugelin-Seiller, R. Bezhenar, J. Brown, J.-J. Cheng, M. Ćujić, S. Dragović, C. Duffa, B. Fiévet, A. Hosseini, K.T. Jung, S. Kamboj, D.-K. Keum, A. Kryshev, D. LePoire, V. Maderich, B.-I. Min, R. Periáñez, T. Sazykina, K.-S. Suh, C. Yu, C. Wang, R. Heling We report an inter-comparison of eight models designed to predict the radiological exposure of radionuclides in marine biota. The models were required to simulate dynamically the uptake and turn... περισσότερα »
Letter on the article “Head and neck sarcoma: Analysis of 29 cases”
Publication date: Available online 21 December 2015 *Source:*European Annals of Otorhinolaryngology, Head and Neck Diseases Author(s): M. Carifi, D. Dall'Olio from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1Jr1aJi via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1NzXUiL via IFTTT
Atypical Lemierre syndrome
Publication date: Available online 21 December 2015 *Source:*European Annals of Otorhinolaryngology, Head and Neck Diseases Author(s): M. Risoud, G. Mortuaire, D. Chevalier, B. Rysman IntroductionLemierre syndrome is a complication of oropharyngeal infection and consists of a combination of internal jugular vein septic thrombophlebitis with septicaemia and distant septic emboli (mainly in the lungs). We describe an atypical case with facial vein and anterior jugular vein thrombophlebitis.Case summaryA 34-year-old woman attended the emergency room with tonsillitis, left head and neck ...περισσότερα »
Artist afflicted with MS races against death to spread her light – Norwalk Reflector
*Artist afflicted with MS races against death to spread her light* *Norwalk Reflector* Then, one day, half of her *tongue* went numb. Hours of hospital tests revealed she had MS. "That was the first time my kids heard the word 'incurable,'" Emily says. "I'd had *cancer* and I'd gotten fixed; but when I had to explain what progressive MS was *…* from #ORL-AlexandrosSfakianakis via simeraentaxei on Inoreader http://ift.tt/1YtyfRg via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1NzXWXY via IFTTT
Evaluation of the GenoType® MTBDRsl assay in Korean patients with MDR or XDR tuberculosis
10.3109/23744235.2015.1125999<br>Hyun Yong Jeong from Infection via ola Kala on Inoreader http://ift.tt/1ImiYdI via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1ZmP2lM via IFTTT
Dermatophytosis in northern Africa
Summary Infections caused by dermatophytes are a global problem and a major public health burden in the world today. In Africa, especially in the northern geographical zone, dermatophytic infections are being reported at an alarming rate. This is mostly because of some local but unique cultural practices, socioeconomic and environmental conditions, lack of reliable diagnostic personnel and facilities and ineffective treatment. Interestingly, the pathogen spectrum and the clinical manifestation are most times different from what is seen in other continents. Several epidemiological ... περισσότερα »
Invasive pulmonary mycosis due to Chaetomium globosum with false-positive galactomannan test: a case report and literature review
[image: cover.gif?v=1&s=1293bca8a559e0d3aa21dc00] Summary In this case, the authors report *Chaetomium globosum* as a cause of invasive pulmonary infection in a patient with Wegener's granulomatosis. Fungal hyphae (KOH and Calcofluor) were seen on direct microscopy of lung biopsy sample and bronchoalveolar lavage (BAL) sample. *C. globosum* isolated on culture clinched the diagnosis of invasive pulmonary infection by *Chaetomium* spp. A positive galactomannan of serum and BAL was repeatedly seen and was utilised for follow-up and as prognostic marker in patient management. The pa... περισσότερα »
Thiamine antivitamins – an opportunity of therapy of fungal infections caused by Malassezia pachydermatis and Candida albicans
Summary Severe skin diseases and systemic fungaemia are caused by *Malassezia pachydermatis* and *Candida albicans* respectively. Antifungal therapies are less effective because of chronic character of infections and high percentage of relapses. Therefore, there is a great need to develop new strategies of antifungal therapies. We previously found that oxythiamine decreases proliferation of yeast (*Saccharomyces cerevisiae*), therefore we suggest that thiamine antivitamins can be considered as antifungal agents. The aim of this study was the comparison of thiamine antivitamins (ox...περισσότερα »
Fluorescent Pseudomonads in the Phyllosphere of Wheat: Potential Antagonists Against Fungal Phytopathogens
Abstract Fluorescent pseudomonads isolated from wheat leaves were characterized regarding their antagonistic potential and taxonomy in relation to protect crop plants from infestation by *Fusarium* and *Alternaria* fungi causing diseases in wheat. Using a dual culture assay, inhibition of fungal growth was found for 40 isolates of 175 fluorescent pseudomonads. Twenty-two of the antagonists were able to suppress strains of *Fusarium* as well as *Alternaria*. By means of real-time qPCR, the *phlD* gene encoding the antibiotic 2,4-diacetylphloroglucinol was detected in 20 isolates. On... περισσότερα »
Lytic Action of the Truncated yncE Gene in Escherichia coli
Abstract We recently found lytic action of the truncated *yncE* gene. When the truncated *yncE* gene of *Salmonella enterica* serovar Paratyphi A was expressed in *Escherichia coli* DH5α under the control of the Ara promoter, bacterial growth was markedly inhibited. In the present study, we characterized this lytic action. The N-terminal 103 aa of YncE, containing a signal peptide, was demonstrated to be essential for inhibition. Microscopic observation showed that the bacterial envelope of *E*. *coli* was damaged by the expression of truncated *yncE*, resulting in the release of ...περισσότερα »
Wenyingzhuangia aestuarii sp. nov., A Marine Bacterium of the Family Flavobacteriaceae Isolated from an Estuary
Abstract A Gram-negative, strictly aerobic, chemoheterotrophic, pale-yellow pigmented, non-motile, rod-shaped bacterial strain, designated MN1-138T, was isolated from water in the tidal zone at the estuary of Heita river, Iwate, Japan, using an in situ cultivation technique. Preliminary analysis based on the 16S rRNA gene sequence revealed that the novel isolate is affiliated with the family *Flavobacteriaceae* of the phylum *Bacteroidetes*, and the highest sequence similarities were found with the species *Wenyingzhuangia heitensis* H-MN17T (97.3 %). The DNA–DNA relatedness betwee... περισσότερα »
SDS-PAGE and Gel IEF: Tool for Differentiation of Methicillin-Resistant and Methicillin-Sensitive Strains of Staphylococcus aureus
Abstract The methicillin-resistant *Staphylococcus aureus* causes difficult-to-treat healthcare-associated infections in humans. For fast and effective selection of an appropriate antibiotic therapy, it is essential to have rapid and reliable methods for differentiation of methicillin-resistant *S. aureus* from less dangerous methicillin-sensitive *S. aureus.* There have been many methods for the identification of methicillin-resistant *S. aureus* described but none has been accepted as an international standard. The most commonly used techniques such as phenotyping and genotyping ... περισσότερα »
The burden of serious human fungal infections in Brazil
[image: cover.gif?v=1&s=1293bca8a559e0d3aa21dc00] Summary In Brazil, human fungal infections are prevalent, however, these conditions are not officially reportable diseases. To estimate the burden of serious fungal diseases in 1 year in Brazil, based on available data and published literature. Historical official data from fungal diseases were collected from Brazilian Unified Health System Informatics Department (DATASUS). For fungal diseases for which no official data were available, assumptions of frequencies were made by estimating based on published literature. The incidence ... περισσότερα »
Safety and efficacy of phage therapy via the intravenous route
Increasing development of antimicrobial resistance is driving a resurgence in interest in phage therapy: the use of bacteriophages to treat bacterial infections. As the lytic action of bacteriophages is unaffected by the antibiotic resistance status of their bacterial target it is thought that phage therapy may have considerable potential in the treatment of a wide range of topical and localized infections. As yet this interest has not extended to intravenous (IV) use, which is surprising given that the historical record shows that phages are likely to be safe and effective when d... περισσότερα »
Monitoring Lysobacter capsici AZ78 using strain specific qPCR reveals the importance of the formulation for its survival in vineyards
Survival in the phyllosphere is a critical feature for biofungicides based on non-spore forming bacteria. Moreover, knowledge of their persistence on plants is important to design effective formulations and application techniques. With this scope, the aim of this work was to develop a specific method to monitor the fate in the environment of *Lysobacter capsici* AZ78, a biocontrol agent of *Plasmopara viticola*, and to evaluate the contribution of formulation in its persistence on grapevine leaves. A strain-specific primer pair derived from REP-PCR fingerprinting was used in quant... περισσότερα »
Adding mucins to an in vitro batch fermentation model of the large intestine induces changes in microbial population isolated from porcine feces depending on the substrate
Adding mucus to *in vitro* fermentation models of the large intestine showed that some genera, namely lactobacilli, are dependent on host-microbiota interactions and that they rely on mucosa layers to increase their activity. This study investigates whether this dependence on mucus is substrate-dependent and to which extend other genera are impacted by the presence of mucus. Inulin and cellulose were fermented *in vitro* by a fecal inoculum from pig in the presence or not of mucin-beads in order to compare fermentation patterns and bacterial communities. Mucins increased final gas...περισσότερα »
Supraglacial bacterial community structures vary across the Greenland ice sheet
The composition and spatial variability of microbial communities that reside within the extensive (>200 000 km2) biologically active area encompassing the Greenland ice sheet (GrIS) is hypothesised to be variable. We examined bacterial communities from cryoconite debris and surface ice across the GrIS, using sequence analysis and quantitative PCR of 16S rRNA genes from co-extracted DNA and RNA. Communities were found to differ across the ice sheet, with 82.8% of the total calculated variation attributed to spatial distribution on a scale of tens of kilometres separation. Amplicons...περισσότερα »
Ungeschützter Geschlechtsverkehr bringt E. coli daher
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Ursachenforschung Nach ungeschütztem Vaginalverkehr kann es zu einer Kolonisation der Vagina mit E. coli kommen. Dafür fanden sich Ursachen unterschiedlicher Art. from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1S7wGmX via IFTTT
Injured condylar cartilage leads to traumatic temporomandibular joint ankylosis
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Publication date: Available online 21 December 2015 Source:Journal of Cranio-Maxillofacial Surgery Author(s): Jiewen Dai, Ningjuan Ouyang, Xiaofang Zhu, Li Huang, Guofang Shen PurposeThe exact mechanisms of traumatic temporomandibular joint ankylosis (TTMJA) are largely unknown. In this study, we explore the role of injured condylar cartilage in the development of TTMJA.Material and MethodsOne-month-old male mice were […]
Iterations of computer- and template assisted mandibular or maxillary reconstruction with free flaps containing the lateral scapular border – evolution of a biplanar plug-on cutting guide
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Publication date: Available online 21 December 2015 Source:Journal of Cranio-Maxillofacial Surgery Author(s): Carl-Peter Cornelius, Goetz Andreas Giessler, Frank Wilde, Marc Christian Metzger, Gerson Mast, Florian Andreas Probst BackgroundComputer-assisted planning and intraoperative implementation using templates have become appreciated modalities in craniofacial reconstruction with fibula and DCIA flaps due to saving in operation time, improved accuracy of […]
Systematic Review of Oral Ulceration with Bone Sequestration
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Publication date: Available online 22 December 2015 Source:Journal of Cranio-Maxillofacial Surgery Author(s): Benjamin Palla, Egon Burian, John Richard Klecker, Riham Fliefel, Sven Otto BackgroundThis article represents the first systematic review entirely dedicated toward a disease called oral ulceration with bone sequestration (OUBS). We performed this review in order to further define and outline this disease. […]
Inter-comparison of dynamic models for radionuclide transfer to marine biota in a Fukushima accident scenario
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Publication date: March 2016 Source:Journal of Environmental Radioactivity, Volume 153 Author(s): J. Vives i Batlle, N.A. Beresford, K. Beaugelin-Seiller, R. Bezhenar, J. Brown, J.-J. Cheng, M. Ćujić, S. Dragović, C. Duffa, B. Fiévet, A. Hosseini, K.T. Jung, S. Kamboj, D.-K. Keum, A. Kryshev, D. LePoire, V. Maderich, B.-I. Min, R. Periáñez, T. Sazykina, K.-S. Suh, […]
Letter on the article “Head and neck sarcoma: Analysis of 29 cases”
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Publication date: Available online 21 December 2015 Source:European Annals of Otorhinolaryngology, Head and Neck Diseases Author(s): M. Carifi, D. Dall’Olio from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1Jr1aJi via IFTTT
Atypical Lemierre syndrome
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Publication date: Available online 21 December 2015 Source:European Annals of Otorhinolaryngology, Head and Neck Diseases Author(s): M. Risoud, G. Mortuaire, D. Chevalier, B. Rysman IntroductionLemierre syndrome is a complication of oropharyngeal infection and consists of a combination of internal jugular vein septic thrombophlebitis with septicaemia and distant septic emboli (mainly in the lungs). We describe […]
Touch-screen devices might help measure child development
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
A new report into toddlers and their usage of touch-screen devices asks whether the technology might be useful to help assess child development. from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1OkC4Dr via IFTTT
Number and distribution of nutrient foramina within the femoral neck and their relationship to the retinacula of Weitbrecht: an anatomical study
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Abstract Precise knowledge of the vascular supply of the femoral head is critical when contemplating surgery around the femoral head and neck junction. To determine the blood supply to the femoral neck, 2417 nutrient foramina from 76 cadaveric specimens were analyzed based on size, number, and distribution. Within the subcapital, transcervical, and basicervical regions of […]
Meetings and Conferences
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Viszeralmedizin 2015;31:458-460 from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1QE5gpF via IFTTT
Injured condylar cartilage leads to traumatic temporomandibular joint ankylosis
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 1 ώρα
Publication date: Available online 21 December 2015 Source:Journal of Cranio-Maxillofacial Surgery Author(s): Jiewen Dai, Ningjuan Ouyang, Xiaofang Zhu, Li Huang, Guofang Shen PurposeThe exact mechanisms of traumatic temporomandibular joint ankylosis (TTMJA) are largely unknown. In this study, we explore the role of injured condylar cartilage in the development of TTMJA.Material and MethodsOne-month-old male mice were […]
Iterations of computer- and template assisted mandibular or maxillary reconstruction with free flaps containing the lateral scapular border – evolution of a biplanar plug-on cutting guide
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 1 ώρα
Publication date: Available online 21 December 2015 Source:Journal of Cranio-Maxillofacial Surgery Author(s): Carl-Peter Cornelius, Goetz Andreas Giessler, Frank Wilde, Marc Christian Metzger, Gerson Mast, Florian Andreas Probst BackgroundComputer-assisted planning and intraoperative implementation using templates have become appreciated modalities in craniofacial reconstruction with fibula and DCIA flaps due to saving in operation time, improved accuracy of […]
Systematic Review of Oral Ulceration with Bone Sequestration
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 1 ώρα
Publication date: Available online 22 December 2015 Source:Journal of Cranio-Maxillofacial Surgery Author(s): Benjamin Palla, Egon Burian, John Richard Klecker, Riham Fliefel, Sven Otto BackgroundThis article represents the first systematic review entirely dedicated toward a disease called oral ulceration with bone sequestration (OUBS). We performed this review in order to further define and outline this disease. […]
Increased Spontaneous Otoacoustic Emissions in Mice with a Detached Tectorial Membrane
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 1 ώρα
Abstract Mutations in genes encoding tectorial membrane (TM) proteins are a significant cause of human hereditary hearing loss (Hildebrand et al. 2011), and several mouse models have been developed to study the functional significance of this accessory structure in the mammalian cochlea. In this study, we use otoacoustic emissions (OAE), signals obtained from the ear […]
Selective Inner Hair Cell Dysfunction in Chinchillas Impairs Hearing-in-Noise in the Absence of Outer Hair Cell Loss
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 1 ώρα
Abstract Poorer hearing in the presence of background noise is a significant problem for the hearing impaired. Ototoxic drugs, ageing, and noise exposure can damage the sensory hair cells of the inner ear that are essential for normal hearing sensitivity. The relationship between outer hair cell (OHC) loss and progressively poorer hearing sensitivity in quiet […]
Excitation Patterns of Standard and Steered Partial Tripolar Stimuli in Cochlear Implants
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 1 ώρα
Abstract Current steering in partial tripolar (pTP) mode has been shown to improve pitch perception and spectral resolution with cochlear implants (CIs). In this mode, a fraction (σ) of the main electrode current is returned within the cochlea and steered between the basal and apical flanking electrodes (with a proportion of α and 1 − α, respectively). […]
Letter on the article “Head and neck sarcoma: Analysis of 29 cases”
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 1 ώρα
Publication date: Available online 21 December 2015 Source:European Annals of Otorhinolaryngology, Head and Neck Diseases Author(s): M. Carifi, D. Dall’Olio from #ORL-AlexandrosSfakianakis via ola Kala on Inoreader http://ift.tt/1Jr1aJi via IFTTT
Atypical Lemierre syndrome
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 1 ώρα
Publication date: Available online 21 December 2015 Source:European Annals of Otorhinolaryngology, Head and Neck Diseases Author(s): M. Risoud, G. Mortuaire, D. Chevalier, B. Rysman IntroductionLemierre syndrome is a complication of oropharyngeal infection and consists of a combination of internal jugular vein septic thrombophlebitis with septicaemia and distant septic emboli (mainly in the lungs). We describe […]
Tuberculose mammaire : à propos de quatre cas à l’hôpital d’instruction des armées Omar Bongo Ondimba (HIAOBO) de Libreville (Gabon)
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 1 ώρα
Résumé La tuberculose mammaire est une localisation rare de la tuberculose extrapulmonaire. Sa fréquence augmente de manière proportionnelle à la pandémie VIH. Nous rapportons quatre cas de tuberculose mammaire diagnostiquée dans le service de médecine polyvalente de l’HIAOBO, dont deux ayant une sérologie VIH positive. Il est nécessaire de connaître cette forme extrapulmonaire car le […]
Milk consumption in relation to incidence of nasopharyngeal carcinoma in 48 countries/regions
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 1 ώρα
Abstract Background Decreasing trends of nasopharyngeal carcinoma (NPC) incidence have been consistently reported in endemic populations but the etiology of NPC remains unclear. The objective of our study was to assess the international and local (Hong Kong) correlations of milk and dairy products per capita consumption with NPC incidence. Methods We conducted an ecological study […]
PharmaForum
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Viszeralmedizin 2015;31:448-449 from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1kek8wf via IFTTT
PharmaNews
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Viszeralmedizin 2015;31:450-456 from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1QE5i0J via IFTTT
Contents Vol. 31, 2015
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Vizeralmedizin 2015;31:461-463 from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1J2QaHj via IFTTT
A novel BAP1 mutation is associated with melanocytic neoplasms and thyroid cancer
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Publication date: Available online 22 December 2015 Source:Cancer Genetics Author(s): Kevin McDonnell, Gregory T. Gallanis, Kathleen A. Heller, Eleni-Marina Melas, Gregory Idos, Julie O. Culver, Sue-Ellen Martin, David H. Peng, Stephen B. Gruber Germline mutations in the tumor suppressor gene, BRCA-1 associated protein (BAP1), underlie a tumor predisposition syndrome characterized by increased risk for numerous […]
Segmental tracheal reconstruction by 3D-printed scaffold: Pivotal role of asymmetrically porous membrane
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Objectives/Hypothesis Three-dimensional (3D) printed scaffold for tracheal reconstruction can substitute the conventional treatment of tracheal stenosis. This study investigated the survival outcomes of segmental tracheal reconstruction using 3D printed polycaprolactone (PCL) scaffold with or without asymmetrically porous membrane in rabbit animal model. Study Design Animal study. Methods Six mature New Zealand white rabbits were categorized […]
Up-regulation of Orai1 expression and store operated Ca 2+ entry following activation of membrane androgen receptors in MCF-7 breast tumor cells
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Abstract Background Membrane androgen receptors (mAR) are functionally expressed in a variety of tumor-cells including the breast tumor-cell line MCF-7. They are specifically activated by testosterone albumin conjugates (TAC). The mAR sensitive signaling includes activation of Ras-related C3 botulinum toxin substrate 1 (Rac1) and reorganization of the actin filament network. Signaling of tumor-cells may further […]
Dermatophytosis in northern Africa
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Summary Infections caused by dermatophytes are a global problem and a major public health burden in the world today. In Africa, especially in the northern geographical zone, dermatophytic infections are being reported at an alarming rate. This is mostly because of some local but unique cultural practices, socioeconomic and environmental conditions, lack of reliable diagnostic […]
Invasive pulmonary mycosis due to Chaetomium globosum with false-positive galactomannan test: a case report and literature review
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Summary In this case, the authors report Chaetomium globosum as a cause of invasive pulmonary infection in a patient with Wegener’s granulomatosis. Fungal hyphae (KOH and Calcofluor) were seen on direct microscopy of lung biopsy sample and bronchoalveolar lavage (BAL) sample. C. globosum isolated on culture clinched the diagnosis of invasive pulmonary infection by Chaetomium […]
Thiamine antivitamins – an opportunity of therapy of fungal infections caused by Malassezia pachydermatis and Candida albicans
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Summary Severe skin diseases and systemic fungaemia are caused by Malassezia pachydermatis and Candida albicans respectively. Antifungal therapies are less effective because of chronic character of infections and high percentage of relapses. Therefore, there is a great need to develop new strategies of antifungal therapies. We previously found that oxythiamine decreases proliferation of yeast (Saccharomyces […]
A Multicomponent Intervention to Optimize Psychotropic Drug Prescription in Elderly Nursing Home Residents: An Italian Multicenter, Prospective, Pilot Study
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Abstract Background Older nursing home residents often have a large number of diseases and frequently require multiple medications; the high consumption of psychotropic drugs is of particular concern. The majority of residents in nursing homes suffer from dementia, and the use of psychotropic drugs in these patients is very high. Prescription for short periods of […]
Resilience of SAR11 bacteria to rapid acidification in the high latitude open ocean
Ubiquitous SAR11 *Alphaproteobacteria* numerically dominate marine planktonic communities. Because they are excruciatingly difficult to cultivate, there is comparatively little known about their physiology and metabolic responses to long- and short- term environmental changes. As surface oceans take up anthropogenic, atmospheric CO2, the consequential process of ocean acidification could affect the global biogeochemical significance of SAR11. Shipping accidents or inadvertent release of chemicals from industrial plants can have strong short-term local effects on oceanic SAR11. Thi... περισσότερα »
Cowden Syndrome and Concomitant Pulmonary Neuroendocrine Tumor: A Presentation of Two Cases
Cowden Syndrome is a rare autosomal dominantly inherited disorder. Patients with Cowden Syndrome are at increased risk of various benign and malignant neoplasms in breast, endometrium, thyroid, gastrointestinal tract, and genitourinary system. Neuroendocrine tumors are ubiquitous neoplasms that may occur anywhere in the human body. Bronchopulmonary neuroendocrine tumors include four different histological subtypes, among these, typical and atypical pulmonary carcinoids. No association between Cowden Syndrome and neuroendocrine tumors has previously been described. We present two c...περισσότερα »
A Comparison of Methods for Capturing Patient Preferences for Delivery of Mental Health Services to Low-Income Hispanics Engaged in Primary Care
Abstract Background Consideration of patient preferences regarding delivery of mental health services within primary care may greatly improve access and quality of care for the many who could benefit from those services. Objectives This project evaluated the feasibility and usefulness of adding a consumer-products design method to qualitative methods implemented within a community-based participatory research (CBPR) framework. Research Design Discrete-choice conjoint experiment (DCE) added to systematic focus group data collection and analysis. Subjects Focus group data were co... περισσότερα »
Kinesio Taping Improves Pain, Range of Motion, and Proprioception in Older Patients With Knee Osteoarthritis
Alexandros G. SfakianakisστοRehabilitation,Sports and Exercise Medicine by Alexandros G. SfakianakisΠριν από 2 ώρες
No abstract available from #Rehabilitation via ola Kala on Inoreader http://ift.tt/1kdF7iE via IFTTT
Importance of Image Guidance in Glenohumeral Joint Injections: Comparing Rates of Needle Accuracy Based on Approach and Physician Level of Training
Alexandros G. SfakianakisστοRehabilitation,Sports and Exercise Medicine by Alexandros G. SfakianakisΠριν από 2 ώρες
[image: image]Objective: This study compared the accuracy of blind glenohumeral joint (GHJ) injections between physical medicine and rehabilitation interventional fellows (inexperienced provider) and a sports medicine board–certified physical medicine and rehabilitation attending physician (experienced provider) using either an anterior or posterior approach. Methods: A retrospective analysis of 162 consecutive patients comprising 165 GHJ injections was performed. All GHJ injections were initially placed via anatomic landmark guidance by either an experienced or an inexperienced pro...περισσότερα »
