The contributions of allergic sensitization and respiratory pathogens to asthma inception
Publication date: March 2016 *Source:*Journal of Allergy and Clinical Immunology, Volume 137, Issue 3 from #ENT via xlomafota13 on Inoreader http://ift.tt/1LYd3rx via IFTTT
Leveraging gene-environment interactions and endotypes for asthma gene discovery
Publication date: March 2016 *Source:*Journal of Allergy and Clinical Immunology, Volume 137, Issue 3 Author(s): Klaus Bønnelykke, Carole Ober Asthma is a heterogeneous clinical syndrome that includes subtypes of disease with different underlying causes and disease mechanisms. Asthma is caused by a complex interaction between genes and environmental exposures; early-life exposures in particular play an important role. Asthma is also heritable, and a number of susceptibility variants have been discovered in genome-wide association studies, although the known risk alleles explain only...περισσότερα »
Microbes and asthma: Opportunities for intervention
Publication date: March 2016 *Source:*Journal of Allergy and Clinical Immunology, Volume 137, Issue 3 Author(s): Hermelijn H. Smits, Pieter S. Hiemstra, Clarissa Prazeres da Costa, Markus Ege, Michael Edwards, Holger Garn, Peter H. Howarth, Tuomas Jartti, Esther C. de Jong, Rick M. Maizels, Ben J. Marsland, Henry J. McSorley, Anne Müller, Petra I. Pfefferle, Huub Savelkoul, Jürgen Schwarze, Wendy W.J. Unger, Erika von Mutius, Maria Yazdanbakhsh, Christian Taube The worldwide incidence and prevalence of asthma continues to increase. Asthma is now understood as an umbrella term for dif... περισσότερα »
The Editors' Choice
Publication date: March 2016 *Source:*Journal of Allergy and Clinical Immunology, Volume 137, Issue 3 Author(s): Cezmi A. Akdis, Zuhair K. Ballas from #ENT via xlomafota13 on Inoreader http://ift.tt/1QXrCTA via IFTTT
Functional neuroimaging studies in functional dyspepsia patients: a systematic review
Abstract Background There is increasing evidence in support of the presence of abnormal central changes (compared to healthy controls) in functional dyspepsia (FD) in addition to the peripheral changes in gastrointestinal tract. Purpose This systematic review aims to provide an integrative understanding of the abnormal functional brain activity, visceral sensation, dyspeptic symptoms, and psychological changes of FD. Electronic and hand searches were conducted to identify functional neuroimaging studies involving FD patients. Sixteen studies were selected and divided into three c... περισσότερα »
A new alternative to cosmetics preservation and the effect of the particle size of the emulsion droplets on preservation efficacy
Abstract Objective This study describes a new alternative combination preservative containing caprylyl glycol, phenethyl alcohol, and glyceryl caprylate and investigates the effects of the particle size of the emulsion droplet on the antimicrobial activity of the said blend in the formulation. Methods The antimicrobial activity of the ingredients and the blend were determined via MIC, MBC, MFC, and fractional inhibitory concentration (FIC) determination using the broth microdilution method. The blend inhibited the microorganism contamination of the oil-in-water emulsion, and its ... περισσότερα »
Hymenoptera venom allergy in children
Natural history of Hymenoptera venom allergy in children not treated with immunotherapy via ScienceDirect Publication: Annals of Allergy, Asthma & Immunology Publication date: March 2016 *Source:*Annals of Allergy, Asthma & Immunology, Volume 116, Issue 3 Author(s): Joanna Lange, Ewa Cichocka-Jarosz, Honorata Marczak, Agnieszka Krauze, Izabela Tarczoń, Ewa Świebocka, Grzegorz Lis, Piotr Brzyski, Anna Nowak-Węgrzyn BackgroundDifferences in treatment approach still exist for children after systemic sting reactions. In addition, there are still some doubts about when systemic reactors sho... περισσότερα »
Allergic sensitization patterns
identified through latent class analysis among children with and without asthma via ScienceDirect Publication: Annals of Allergy, Asthma & Immunology Publication date: March 2016 *Source:*Annals of Allergy, Asthma & Immunology, Volume 116, Issue 3 Author(s): Qixuan Chen, Xiaobo Zhong, Luis Acosta, Adnan Divjan, Andrew Rundle, Inge F. Goldstein, Rachel L. Miller, Matthew S. Perzanowski BackgroundSpecific patterns of allergic sensitization to common allergens may provide relevant clinical insight into asthma risk.ObjectiveTo identify patterns of allergic sensitization based on multiple i...περισσότερα »
Biomarkers of the involvement of mast cells, basophils and eosinophils in asthma and allergic diseases
Biomarkers of the involvement of mast cells, basophils and eosinophils in asthma and allergic diseases: Dean D. MetcalfeEmail author, Ruby Pawankar, Steven J. Ackerman, Cem Akin, Frederic Clayton, Franco H. Falcone, Gerald J. Gleich, Anne-Marie Irani, Mats W. Johansson, Amy D. Klion, Kristin M. Leiferman, Francesca Levi-Schaffer, Gunnar Nilsson, Yoshimichi Okayama, Calman Prussin, John T. Schroeder, Lawrence B. Schwartz, Hans-Uwe Simon, Andrew F. Walls and Massimo Triggiani World Allergy Organization Journal20169:7 DOI: 10.1186/s40413-016-0094-3© Metcalfe et al. 2016 Receiv... περισσότερα »
IJERPH, Vol. 13, Pages 284: Spatial Patterns of Heat-Related Cardiovascular Mortality in the Czech Republic
Alexandros G. SfakianakisστοNews in OtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 4 δευτερόλεπτα
The study examines spatial patterns of effects of high temperature extremes on cardiovascular mortality in the Czech Republic at a district level during 1994–2009. Daily baseline mortality for each district was determined using a single location-stratified generalized additive model. Mean relative deviations of mortality from the baseline were calculated on days exceeding the 90th percentile of mean daily temperature in summer, and they were correlated with selected demographic, socioeconomic, and physical-environmental variables for the districts. Groups of districts with similar... περισσότερα »
Nutrients, Vol. 8, Pages 142: Vitamin D and Sunlight Exposure in Newly-Diagnosed Parkinson’s Disease
Alexandros G. SfakianakisστοNews in OtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 4 δευτερόλεπτα
Circulating vitamin D has previously been found to be lower in patients with Parkinson's disease (PD), while the effects of sunlight exposure have not yet been fully investigated. Therefore, we evaluated the associations between serum vitamin D, vitamin D intake, sunlight exposure, and newly-diagnosed PD patients in a Chinese population. This case-control study measured serum 25-hydroxyvitamin D (25(OH)D) levels and sunlight exposure in 201 patients with newly-diagnosed PD and 199 controls without neurodegenerative diseases. Data on vitamin D intake and sunlight exposure were obta... περισσότερα »
MCA, Vol. 21, Pages 2: Numerical Simulation Study on the Flow Field Out of a Submerged Abrasive Water Jet Nozzle
Alexandros G. SfakianakisστοNews in OtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 4 δευτερόλεπτα
In order to optimize the parameters of pre-mixed abrasive water jet cutting technology, make it more efficient in the coal mine gas environment and solve the problem of hard coal and the difficulty of rock drilling, FLUENT software was used to get the isothermal, incompressible, steady flow field out of a submerged abrasive water jet nozzle through numerical simulation, with different particle sizes and different confining pressures under submerged conditions. The results show that, under submerged conditions, the maximum velocity of the abrasive particle outside the pre-mixed abr... περισσότερα »
Chemotherapy with or without autologous cytokine-induced killer cell transfusion as the first-line treatment for stage IV gastrointestinal cancer: a phase II clinical trial
Abstract Objective To investigate the efficacy of autologous cytokine-induced killer (CIK) cell therapy combined with chemotherapy versus chemotherapy alone for the treatment of stage IV gastrointestinal (GI) cancer in the first-line setting. Methods Thirty-three patients diagnosed with stage IV GI cancer were divided into chemotherapy plus CIK group (chemo–CIK, *n* = 16) and chemotherapy-alone group (chemo-alone, *n* = 17). Autologous peripheral blood mononuclear cells were separated by flow cytometry, cultured in vitro to induce CIK cells, and transfused into patients on days 1... περισσότερα »
Enhancement of antitumor activity of the oxazaphosphorine cytostatic SUM-IAP by N -methylformamide
Abstract Purpose SUM-IAP has been developed with the aim to optimize therapeutic response and minimize toxic reactions of oxazaphosphorine cytostatics. In therapy tests in mice, the primary tumor was successfully eradicated, but animals died due to formation of lethal metastases. We supposed that high activities of SUM-IAP detoxifying enzymes caused metastasis formation in the liver. Therefore, therapy tests with SUM-IAP in combination with cisplatin and *N*-methylformamide (NMF), which were not detoxified in the liver, were carried out. Method Antitumor activity was assayed in f... περισσότερα »
Comparison of hypoxia-activated prodrug evofosfamide (TH-302) and ifosfamide in preclinical non-small cell lung cancer models
10.1080/15384047.2016.1139268<br>Jessica D. Sun from Cancer via ola Kala on Inoreader http://ift.tt/1oUsvzv via IFTTT
World Allergy Organization-McMaster University Guidelines for Allergic Disease Prevention (GLAD-P): Prebiotics
World Allergy Organization-McMaster University Guidelines for Allergic Disease Prevention (GLAD-P): Prebiotics: The prevalence of allergic diseases in infants, whose parents and siblings do not have allergy, is approximately 10 % and reaches 20–30 % in those with an allergic first-degree relative. Carlos A. Cuello-GarciaView ORCID ID profile, Alessandro Fiocchi†, Ruby Pawankar†, Juan José Yepes-Nuñez, Gian Paolo Morgano, Yuan Zhang, Kangmo Ahn, Suleiman Al-Hammadi, Arnav Agarwal, Shreyas Gandhi, Kirsten Beyer, Wesley Burks, Giorgio W. Canonica, Motohiro Ebisawa, Rose Kamenwa, Be... περισσότερα »
Gut Microbiota-Induced Immunoglobulin G Controls Systemic Infection
by Symbiotic Bacteria and Pathogens via ScienceDirect Publication: Immunity Publication date: Available online 2 March 2016 *Source:*Immunity Author(s): Melody Y. Zeng, Daniel Cisalpino, Saranyaraajan Varadarajan, Judith Hellman, H. Shaw Warren, Marilia Cascalho, Naohiro Inohara, Gabriel Núñez The gut microbiota is compartmentalized in the intestinal lumen and induces local immune responses, but it remains unknown whether the gut microbiota can induce systemic response and contribute to systemic immunity. We report that selective gut symbiotic gram-negative bacteria were able to diss...περισσότερα »
Association of food allergy and atopic dermatitis exacerbations
Association of food allergy and atopic dermatitis exacerbations: Atopic dermatitis (AD) and food allergy frequently coexist in children. AbstractBackground Atopic dermatitis (AD) and food allergy frequently coexist in children. Objective To examine the association between food allergy and AD. Methods Between 2001 and 2011, children referred to our tertiary care center underwent double-blind, placebo-controlled food challenges (DBPCFCs) for one or more suspected food allergies as part of regular care. Immediate reactions were observed and recorded by allergy nursing staff, whereas la... περισσότερα »
Risk factors for fatal and nonfatal reactions to subcutaneous immunotherapy
Risk factors for fatal and nonfatal reactions to subcutaneous immunotherapy: In 2008, an annual surveillance study of systemic reactions (SRs) from subcutaneous immunotherapy (SCIT) injections was initiated in North America. AbstractBackground In 2008, an annual surveillance study of systemic reactions (SRs) from subcutaneous immunotherapy (SCIT) injections was initiated in North America. Objective To define the incidence of SRs to SCIT. Methods From 2008 to 2013, 27% to 51% of American Academy of Allergy, Asthma, and Immunology and American College of Asthma, Allergy, and Immunolog... περισσότερα »
Type 1 hereditary angioedema
in a 72-year-old woman by Jesús Miguel García-Menaya, Concepción Cordobés-Durán, María Angeles Zambonino, Alba Catherine Mahecha, Pedro Bobadilla-González via Annals of Allergy, Asthma & Immunology Hereditary angioedema (HAE) is an autosomal dominant disease caused by a deficiency in functional C1 esterase inhibitor (C1INH). It is characterized by recurrent episodes of nonpruritic, nonpitting, subcutaneous, or submucosal edema that involves the arms, legs, hands, feet, bowels, genitalia, trunk, face, tongue, or larynx. Symptoms typically begin in childhood, worsen around puberty, an... περισσότερα »
Comments on the Italian Society of Endocrinology recommendations on post-surgical thyroid ablation in differentiated thyroid cancer
from thyroid via a.lsfakia on Inoreader http://ift.tt/1VV3uiG via IFTTT
Factors associated with removal of a radial head prosthesis placed for acute trauma
Injury from Emergency Medicine via ola Kala on Inoreader http://ift.tt/1TdJb1V via IFTTT
Comparison of intravenous morphine vs paracetamol in sciatica: a randomized placebo controlled trial
Academic Emergency Medicine from Emergency Medicine via ola Kala on Inoreader http://ift.tt/21biavm via IFTTT
Effect of serum growth differentiation factor-15 and the syntax score on 2-year outcomes in patients with acute coronary syndrome
The American Journal of Cardiology from Emergency Medicine via ola Kala on Inoreader http://ift.tt/21bi86S via IFTTT
Is there a difference in efficacy, safety and cost-effectiveness between three factor and four factor prothrombin complex concentrates among trauma patients on oral anticoagulants?
Journal of Critical Care from Emergency Medicine via ola Kala on Inoreader http://ift.tt/1TdJbPr via IFTTT
The relationship between fibrinogen to albumin ratio and severity of coronary artery disease in patients with STEMI
The American Journal of Emergency Medicine from Emergency Medicine via ola Kala on Inoreader http://ift.tt/21bi72E via IFTTT
UF Health Shands Hospital officials note late increase in flu cases
UF Health from Emergency Medicine via ola Kala on Inoreader http://ift.tt/1TdJ9Hz via IFTTT
What do we know about the association between firearm legislation and firearm-related injuries?
Epidemiologic Reviews from Emergency Medicine via ola Kala on Inoreader http://ift.tt/21bi86J via IFTTT
Effects of Virtual Reality Training (Exergaming) Compared to Alternative Exercise Training and Passive Control on Standing Balance and Functional Mobility in Healthy Community-Dwelling Seniors: A Meta-Analytical Review
Sports Medicine from Emergency Medicine via ola Kala on Inoreader http://ift.tt/1TdJbz5 via IFTTT
Should predictive scores based on vital signs be used in the same way as those based on laboratory data? A hypothesis generating retrospective evaluation of in-hospital mortality by four different scoring systems
Resuscitation from Emergency Medicine via ola Kala on Inoreader http://ift.tt/21bi86F via IFTTT
Airborne pollen concentrations and emergency room visits for myocardial infarction: a multicity case-crossover study in Ontario, Canada
American Journal of Epidemiology from Emergency Medicine via ola Kala on Inoreader http://ift.tt/1TdJbz1 via IFTTT
Missed ischemic stroke diagnosis in the emergency department by emergency medicine and neurology services
Stroke from Emergency Medicine via ola Kala on Inoreader http://ift.tt/21bi7Qj via IFTTT
Cost effectiveness of field trauma triage among injured adults served by emergency medical services
Journal of the American College of Surgeons from Emergency Medicine via ola Kala on Inoreader http://ift.tt/1TdJbiF via IFTTT
High-Impact Hepatitis C Virus Testing for Injection Drug Users (HIT IDU) in an Urban Emergency Department
The American Journal of Emergency Medicine from Emergency Medicine via ola Kala on Inoreader http://ift.tt/21bi7Qf via IFTTT
Does perceived injustice correlate with pain intensity and disability in orthopedic trauma patients?
Injury from Emergency Medicine via ola Kala on Inoreader http://ift.tt/1TdJ9r2 via IFTTT
Emergency calls and need for emergency care in patients looked after by a palliative care team: Retrospective interview study with bereaved relatives
BMC Palliative Care from Emergency Medicine via ola Kala on Inoreader http://ift.tt/21bi6Md via IFTTT
Microbes and asthma
: Opportunities for intervention via Allergy and Clinical Immunology Publication date: March 2016 *Source:*Journal of Allergy and Clinical Immunology, Volume 137, Issue 3 Author(s): Hermelijn H. Smits, Pieter S. Hiemstra, Clarissa Prazeres da Costa, Markus Ege, Michael Edwards, Holger Garn, Peter H. Howarth, Tuomas Jartti, Esther C. de Jong, Rick M. Maizels, Ben J. Marsland, Henry J. McSorley, Anne Müller, Petra I. Pfefferle, Huub Savelkoul, Jürgen Schwarze, Wendy W.J. Unger, Erika von Mutius, Maria Yazdanbakhsh, Christian Taube The worldwide incidence and prevalence of asthma continues... περισσότερα »
MHC class I chain-related molecule A and B expression is upregulated by cisplatin and associated with good prognosis in patients with non-small cell lung cancer
Abstract MHC class I chain-related molecule A and B (MICA/B) are NK group 2 member D (NKG2D) ligands, which are broadly expressed in transformed cells. Both DNA damage-induced ataxia-telangiectasia-mutated (ATM)- and ATM and Rad3-related protein kinases (ATM–ATR) signaling and oncogene-induced PI3K–AKT signaling regulate the expression of NKG2D ligands, which promote NK cell-mediated cytotoxicity via NKG2D–NKG2D ligand interactions. NKG2D ligand overexpression was recently reported to be correlated with good prognosis in several types of cancer. However, the prognostic significance... περισσότερα »
The role of allergen components for the diagnosis of latex-induced occupational asthma
The role of allergen components for the diagnosis of latex-induced occupational asthma: [image: cover.gif?v=1&s=ff195289b99d5ad4af62a487] Abstract Background Recombinant Hevea brasiliensis (rHev b) natural rubber latex (NRL) allergen components have been developed to assess the patients’ allergen sensitization profile and to improve the diagnosis of NRL allergy. Objective To examine whether the determination of specific IgE (sIgE) reactivity to a panel of recombinant allergen components would be helpful for diagnosing NRL-induced occupational asthma (OA) in predicting the outcome... περισσότερα »
The contributions of allergic sensitization and respiratory pathogens to asthma inception
The contributions of allergic sensitization and respiratory pathogens to asthma inception via Allergy and Clinical Immunology Publication date: March 2016 *Source:*Journal of Allergy and Clinical Immunology, Volume 137, Issue 3 Author(s): Daniel J. Jackson, James E. Gern, Robert F. Lemanske Of the chronic diseases affecting grade-school children, asthma is the most common and accounts for the greatest number of school days missed. Moreover, it can influence family dynamics and function in other ways, and unfortunately, it can also be associated with mortality, particularly in the inner... περισσότερα »
Inflammatory endotypes of chronic rhinosinusitis
based on cluster analysis of biomarkers via Allergy and Clinical Immunology Publication date: Available online 4 March 2016 *Source:*Journal of Allergy and Clinical Immunology Author(s): Peter Tomassen, Griet Vandeplas, Thibaut Van Zele, Lars-Olaf Cardell, Julia Arebro, Heidi Olze, Ulrike Förster-Ruhrmann, Marek L. Kowalski, Agnieszka Olszewska-Ziąber, Gabriele Holtappels, Natalie De Ruyck, Xiangdong Wang, Cornelis Van Drunen, Joaquim Mullol, Peter Hellings, Valerie Hox, Elina Toskala, Glenis Scadding, Valerie Lund, Luo Zhang, Wytske Fokkens, Claus Bachert BackgroundCurrent phenotypin...περισσότερα »
MHC class I chain-related molecule A and B expression is upregulated by cisplatin and associated with good prognosis in patients with non-small cell lung cancer
Abstract MHC class I chain-related molecule A and B (MICA/B) are NK group 2 member D (NKG2D) ligands, which are broadly expressed in transformed cells. Both DNA damage-induced ataxia-telangiectasia-mutated (ATM)- and ATM and Rad3-related protein kinases (ATM–ATR) signaling and oncogene-induced PI3K–AKT signaling regulate the expression of NKG2D ligands, which promote NK cell-mediated cytotoxicity via NKG2D–NKG2D ligand interactions. NKG2D ligand overexpression was recently reported to be correlated with good prognosis in several types of cancer. However, the prognostic significance... περισσότερα »
Staphylococcus aureus–derived lipoteichoic acid induces temporary T-cell paralysis independent of Toll-like receptor 2
Staphylococcus aureus–derived lipoteichoic acid induces temporary T-cell paralysis independent of Toll-like receptor 2 via Allergy and Clinical Immunology Publication date: Available online 3 March 2016 *Source:*Journal of Allergy and Clinical Immunology Author(s): Susanne Kaesler, Yuliya Skabytska, Ko-Ming Chen, Wolfgang E. Kempf, Thomas Volz, Martin Köberle, Florian Wölbing, Ulrike Hein, Thomas Hartung, Carsten Kirschning, Martin Röcken, Tilo Biedermann BackgroundThe interplay between microbes and surface organs, such as the skin, shapes a complex immune system with several checks and... περισσότερα »
Use of a purified collagen membrane to aid closure of palatal fistulae
Use of a purified collagen membrane to aid closure of palatal fistulae via British Association of Plastic Surgeons Publication date: Available online 2 March 2016 *Source:*Journal of Plastic, Reconstructive & Aesthetic Surgery Author(s): Duncan D. Atherton, John G. Boorman IntroductionFistula formation remains a difficult clinical problem following closure of palatal clefts. There is also a significant recurrence rate after attempted closure. We present our results of fistula closure augmented with Bio-Gide®; a purified porcine collagen membrane designed to promote guided tissue regener...περισσότερα »
Oral Anticoagulants in Plastic Surgery
Novel via British Association of Plastic Surgeons Publication date: Available online 2 March 2016 *Source:*Journal of Plastic, Reconstructive & Aesthetic Surgery Author(s): C.F. Munson, A.J. Reid Novel oral anticoagulants (NOACs) have emerged as a good alternative to warfarin in the prevention of stroke for patients with atrial fibrillation. NOAC use is increasing rapidly therefore greater understanding of their use in the perioperative period is important for optimal care.Studies and reviews that reported on the use of NOACs were identified, with particular focus on the perioperative... περισσότερα »
Raman scattering enhanced within the plasmonic gap between an isolated Ag triangular nanoplate and Ag film
Enhanced electromagnetic field in the tiny gaps between metallic nanostructures holds great promise in optical applications. Herein, we report novel out-of-plane nanogaps composed of micrometer-sized Ag triangular nanoplates (AgTN) on Ag films. Notably, the new coupled plasmonic structure can dramatically enhance the surface-enhanced Raman scattering (SERS) by visible laser excitation, although the micrometer-sized AgTN has localized plasmon resonance at infrared wavelength. This enhancement is derived from the gap plasmon polariton between the AgTN and Ag film, which is excited v... περισσότερα »
Relationship between phosphorylation of sperm-specific antigen and prognosis of lung adenocarcinoma
Publication date: Available online 3 March 2016 *Source:*Journal of Proteomics Author(s): Akiko Okayama, Yayoi Kimura, Yohei Miyagi, Takashi Oshima, Fumihiro Oshita, Hiroyuki Ito, Haruhiko Nakayama, Takuya Nagashima, Yasushi Rino, Munetaka Masuda, Akihide Ryo, Hisashi Hirano Lung cancer is generally considered as a highly malignant cancer. A major challenge for the management of lung adenocarcinoma patients is to predict the clinical course of the disease after resection. We analyzed the different levels of phosphorylation of proteins in lung adenocarcinoma tissues between a poor pr... περισσότερα »
Brownian-motion based simulation of stochastic reaction–diffusion systems for affinity based sensors
[image: nanoaa1856f1_lr.jpg] In this work, we develop a 2D algorithm for stochastic reaction–diffusion systems describing the binding and unbinding of target molecules at the surfaces of affinity-based sensors. In particular, we simulate the detection of DNA oligomers using silicon-nanowire field-effect biosensors. Since these devices are uniform along the nanowire, two dimensions are sufficient to capture the kinetic effects features. The model combines a stochastic ordinary differential equation for the binding and unbinding of target molecules as well as a diffusion equation for... περισσότερα »
PlantPReS: A database for plant proteome response to stress
Publication date: Available online 3 March 2016 *Source:*Journal of Proteomics Author(s): Seyed Ahmad Mousavi, Farhad Movahedi Pouya, Mohammad Reza Ghaffari, Mehdi Mirzaei, Akram Ghaffari, Mehdi Alikhani, Mohammad Ghareyazie, Setsuko Komatsu, Paul A. Haynes, Ghasem Hosseini Salekdeh About 75% of plant yield potential has been estimated to be lost to environmental stresses, even in developed agricultures. To facilitate the biotechnological improvement of crop productivity, genes and proteins that control crop adaptation to a wide range of environments will need to be identified. Due ... περισσότερα »
Cold-bonding in sub-10 nm indium tin oxide nanorods
Cold-bonding in a typical metal oxide material nanostructure, indium tin oxide nanorods (ITONs), was observed and studied by combining precise in situ nano-manipulation, transmission electron microscopy (TEM) observation and on-line electrical properties measurements. Our studies revealed an oriented attachment process caused by enhanced atom mobility or diffusion and rearrangement at the contact, which worked efficiently in reconnecting the ITONs. Electrical measurements exhibited low contact resistance between the re-connectable ITON segments. Our observations indicate that smal...περισσότερα »
Multifunctional reduction-responsive SPIO&DOX-loaded PEGylated polymeric lipid vesicles for magnetic resonance imaging-guided drug delivery
Multifunctional superparamagnetic iron-oxide (SPIO)-based nanoparticles have been emerging as candidate nanosystems for cancer diagnosis and therapy. Here, we report the use of reduction- responsive SPIO/doxorubicin (DOX)-loaded poly(ethylene glycol) monomethyl ether (PEG)ylated polymeric lipid vesicles (SPIO&DOX-PPLVs) as a novel theranostic system for tumor magnetic resonance imaging (MRI) diagnosis and controlled drug delivery. These SPIO&DOX-PPLVs are composed of SPIOs that function as MR contrast agents for tumor enhancement and PPLVs as polymer matrices for encapsulating SPI... περισσότερα »
The microcirculation after soft tissue reconstruction of the burned outer ear
Analysis of the microcirculation after soft tissue reconstruction of the burned outer ear in patients with severe burn injuries via British Association of Plastic Surgeons Publication date: Available online 2 March 2016 *Source:*Journal of Plastic, Reconstructive & Aesthetic Surgery Author(s): Fabian Medved, Raluca Medesan, Jens Martin Rothenberger, Hans-Eberhard Schaller, Thomas Schoeller, Theodora Manoli, Lennart Weitgasser, Aline Naumann, Laurenz Weitgasser Reconstruction of soft tissue defects of the burned ear remains one of the most difficult tasks for the reconstructive surgeon. ... περισσότερα »
Planning digital artery perforators using color Doppler ultrasonography
Planning digital artery perforators using color Doppler ultrasonography: A preliminary report: Digital artery perforator (DAP) flaps have been applied for the coverage of finger soft tissue defects. Although an advantage of this method is that there is no scarification of the digital arteries, it is difficult to identify the location of the perforators during intraoperative elevation of the DAP flap. In this study, anatomically reliable locations of DAPs were confirmed using color Doppler ultrasonography (US) in healthy volunteers. A successful case using an adiposal-only DAP flap f... περισσότερα »
Congenital malformation of the nose, affecting the nasal dorsum and the supra-tip
Une malformation nasale congénitale non retrouvée dans la littérature : à propos de 5 cas via Plastique Esthétique Publication date: Available online 2 March 2016 *Source:*Annales de Chirurgie Plastique Esthétique Author(s): T.R. Colson, B. Bertrand, N. Degardin, J. Bardot, D. Casanova But de l’étudeCinq cas d’une même malformation congénitale du nez sont présentés, dont il ne semble pas exister d’équivalent dans la littérature. Cette malformation touche l’arête nasale et le supra-tip. Nous souhaitions présenter cette pathologie.Patients et méthodesCinq patients présentant une malform...περισσότερα »
Carcinoma Ex Pleomorphic Adenoma of the Lacrimal Gland with Epithelial-Myoepithelial Carcinoma Histologic Type.
Carcinoma Ex Pleomorphic Adenoma of the Lacrimal Gland with Epithelial-Myoepithelial Carcinoma Histologic Type.: A 53-year-old woman presented with a 1-month history of decreased vision and progressive left periorbital fullness. Exam and radiography confirmed a left lacrimal gland mass causing mass effect on the globe and a compressive optic neuropathy. Orbitotomy with excisional biopsy confirmed carcinoma ex pleomorphic adenoma with epithelial and myoepithelial differentiation. Following a negative systemic workup, the patient underwent radiation therapy and remains free of clinica...περισσότερα »
Lacrimal Sac Wall Granuloma Simulating a Neoplasm.
Lacrimal Sac Wall Granuloma Simulating a Neoplasm.:
Increasing the survival of transverse rectus abdominis musculocutaneous flaps with a Botulinum Toxin-A Injection
: A comparison of surgical and chemical flap delay methods via British Association of Plastic Surgeons Publication date: Available online 3 March 2016 *Source:*Journal of Plastic, Reconstructive & Aesthetic Surgery Author(s): Gökhan Temiz, Nebil Yeşiloğlu, Hakan Şirinoğlu, Ali Cem Akpınar, Murat Sarıcı, Deniz Filinte, Gaye Taylan Filinte, Mehmet Bozkurt BackgroundBotulinum Toxin type-A (Btx-A) is a commonly used drug for both cosmetic and therapeutic purposes. The effects of Btx-A on skin and muscle flaps and the related mechanisms have been described previously. In this study, we used ... περισσότερα »
The Effect of Mental Rehearsal and Cognitive Visualization on Microsurgery Skills
A Randomized Control Trial Exploring the Effect of Mental Rehearsal and Cognitive Visualization on Microsurgery Skills: J reconstr Microsurg DOI: 10.1055/s-0036-1577566 Background Many factors are known to influence the performance of surgeons within the operating theater, including tiredness, previous experience, and stress levels. The effects of mental rehearsal and cognitive visualization on microsurgical skills have not been assessed. Methods Thirty-six subjects recruited from the Northwick Park Microsurgery Skills Course were randomized into three groups; (1) a control group (... περισσότερα »
Vascular Anatomy and Clinical Application of the Free Proximal Ulnar Artery Perforator Flaps
Vascular Anatomy and Clinical Application of the Free Proximal Ulnar Artery Perforator Flaps: [image: image] Background: There is a dearth of detailed published work on the anatomy of ulnar artery perforators. The objective of this study was to fully document the vascular basis of the free proximal ulnar artery perforator flap and report its use in reconstruction of the hand. Methods: (1) The ulnar artery perforators were studied in 25 fresh cadavers and 10 cast preparations. Cadavers were injected with lead oxide for 3-dimensional reconstruction. The origin, course, and distributi... περισσότερα »
Skin grafting for the treatment of chronic ulcers
Skin grafting for the treatment of chronic leg ulcers – a systematic review in evidence-based medicine: Abstract Skin grafting is one of the most common surgical procedures in the area of non-healing wounds by which skin or a skin substitute is placed over a wound to replace and regenerate the damaged skin. Chronic leg ulcers are an important problem and a major source of expense for Western countries and for which many different forms of treatment have been used. Skin grafting is a method of treatment that decreases the area of chronic leg ulcers or heals them completely, thus imp... περισσότερα »
The application of acellular dermis in reconstructing full-thickness skin defects
Retrospective study of the application of acellular dermis in reconstructing full-thickness skin defects: Abstract The purpose of the article is to evaluate the acellular dermis' utility in reconstructing full-thickness defects after scar contracture releasing and giant nevus resection. From the year 2012 to 2014, 18 consecutive patients underwent composite graft (thin autograft and alloderma) transplantation. Among these patients, 16 patients suffered from burned scar contracture in the upper extremities, and two young cases were met with giant nevus on the upper extremity. Ten of... περισσότερα »
Antimicrobial activities of ZnO, citric acid, and a mixture of both against Propionibacterium acnes
Evaluation of antimicrobial activities of ZnO, citric acid, and a mixture of both against Propionibacterium acnes: Abstract Objective In this study, antimicrobial activities of ZnO of three different particle sizes, of citric acid (CA), and of mixtures of ZnO and CA were confirmed against *Propionibacterium acnes*. Methods ZnO with the smallest particle size showed relatively high antimicrobial activity by disc diffusion assay and broth macrodilution assay. The mixtures of ZnO and CA also showed relatively high antimicrobial activity when the particle size of ZnO was the smallest. F... περισσότερα »
A new alternative combination preservative containing caprylyl glycol, phenethyl alcohol, and glyceryl caprylate and investigates the effects of the particle size of the emulsion droplet on the antimicrobial activity of the said blend in the formulation
A new alternative to cosmetics preservation and the effect of the particle size of the emulsion droplets on preservation efficacy: Abstract Objective This study describes a new alternative combination preservative containing caprylyl glycol, phenethyl alcohol, and glyceryl caprylate and investigates the effects of the particle size of the emulsion droplet on the antimicrobial activity of the said blend in the formulation. Methods The antimicrobial activity of the ingredients and the blend were determined via MIC, MBC, MFC, and fractional inhibitory concentration (FIC) determination ... περισσότερα »
Synthesis of "amphiphilic" carbon dots and their application for the analysis of iodine species (I2, I- and IO3-) in high saline water
[image: CrossMark.jpg] *Analyst*, 2016, Accepted Manuscript *DOI*: 10.1039/C5AN02643A, Paper Meina Wang, baozhan zheng, Feng Yang, Juan Du, Yong Guo, Jianyuan Dai, Lei Yan, Dan Xiao ABSTRACT: "Amphiphilic" carbon dots (A-CDs) with strong green fluorescent emission were synthesized with a simple and green method at room temperature. The characterizations demonstrated the synthesized A-CDs have both of... The content of this RSS Feed (c) The Royal Society of Chemistry from BioChemistry via xlomafota13 on Inoreader http://ift.tt/1QpACNS via IFTTT
A proton pump inhibitor, elimination diet and/or budesonide for eosinophilic oesophagitis
A prospective open clinical trial of a proton pump inhibitor, elimination diet and/or budesonide for eosinophilic oesophagitis: Summary Background Elimination diets and high-dose proton pump inhibitors (PPI) are advocated as first-line treatments in patients with eosinophilic oesophagitis (EoE). Aim To record the treatment outcome for patients with EoE prospectively managed according to a clinical algorithm. Methods Patients with oesophageal eosinophilia commenced esomeprazole 40 mg twice daily for 8 weeks. Those in histological remission were re-classified as PPI-responsive oesophag... περισσότερα »
Complete-mouth rehabilitation using a 3D printing technique and the CAD/CAM double scanning method
: A clinical report via The Journal of Prosthetic Dentistry Publication date: Available online 2 March 2016 *Source:*The Journal of Prosthetic Dentistry Author(s): Han-Sung Joo, Sang-Won Park, Kwi-Dug Yun, Hyun-Pil Lim According to evolving computer-aided design/computer-aided manufacturing (CAD/CAM) technology, ceramic materials such as zirconia can be used to create fixed dental prostheses for partial removable dental prostheses. Since 3D printing technology was introduced a few years ago, dental applications of this technique have gradually increased. This clinical report presents a...περισσότερα »
Compensation of skeletal Class III malocclusion by isolated extraction of mandibular teeth
Compensation of skeletal Class III malocclusion by isolated extraction of mandibular teeth: Abstract ObjectivesTo retrospectively compare two compensatory approaches taken in skeletal Class III patients during the main treatment stage, including a study group of multiband treatment plus isolated extraction of mandibular teeth and a control group of multiband treatment without extraction of teeth. Patients and methodsThe extraction group included 22 (12 female, 10 male) patients receiving compensatory multiband treatment for a mean of 3.47 ± 1.14 years and 16.22 ± 1.92 years ol... περισσότερα »
Occlusal stability after Herbst treatment of patients with retrognathic and prognathic facial types
Occlusal stability after Herbst treatment of patients with retrognathic and prognathic facial types: Abstract ObjectivesThe purpose of this study was to assess and compare occlusal changes induced by Herbst treatment and the stability of these changes in patients with retrognathic and prognathic facial types. Patients and methodsThe sample comprised 11 retrognathic (SNA ≤76°, SNB ≤72°, ML/NSL ≥36°) and 10 prognathic (SNA ≥83°, SNB ≥80°, ML/NSL ≤32°) patients with Class II molar relationships of ≥0.5 cusp widths bilaterally or ≥1.0 cusp width unilaterally. Both groups involved s...περισσότερα »
Oral Health-related Beliefs, Behaviors, and Outcomes through the Life Course
Oral Health-related Beliefs, Behaviors, and Outcomes through the Life Course: Complex associations exist among socioeconomic status (SES) in early life, beliefs about oral health care (held by individuals and their parents), and oral health–related behaviors. The pathways to poor adult oral health are difficult to model and describe, especially due to a lack of longitudinal data. The study aim was to explore possible pathways of oral health from birth to adulthood (age 38 y). We hypothesized that higher socioeconomic position in childhood would predict favorable oral health beliefs... περισσότερα »
Levels of Candidate Periodontal Pathogens in Subgingival Biofilm
Levels of Candidate Periodontal Pathogens in Subgingival Biofilm: In recent years, several new periodontal taxa have been associated with the etiology of periodontitis. A recent systematic review provides further support for the pathogenic role of 17 species/phylotypes. Thus, the aim of this study was to assess the prevalence and levels of these species in subjects with generalized chronic periodontitis (GChP; *n* = 30), generalized aggressive periodontitis (GAgP; *n* = 30), and periodontal health (PH; *n* = 30). All subjects underwent clinical and microbiological assessment. Nine ... περισσότερα »
Identification of Stem Cells in the Secretory Complex of Salivary Glands
Identification of Stem Cells in the Secretory Complex of Salivary Glands: Salivary glands have an essential secretory function for maintaining oral and overall health. The epithelial compartment of the gland is composed of several highly specialized cell types that cooperate to secrete and deliver saliva to the oral cavity. The mouse submandibular gland has been used as a model for major salivary glands in human. The secretory complex in this model is composed of 2 secretory compartments, including acini and granular ducts connected by intercalated ducts. Contractile myoepithelial c...περισσότερα »
Evaluation of antimicrobial activities of ZnO, citric acid, and a mixture of both against Propionibacterium acnes
Abstract Objective In this study, antimicrobial activities of ZnO of three different particle sizes, of citric acid (CA), and of mixtures of ZnO and CA were confirmed against *Propionibacterium acnes*. Methods ZnO with the smallest particle size showed relatively high antimicrobial activity by disc diffusion assay and broth macrodilution assay. The mixtures of ZnO and CA also showed relatively high antimicrobial activity when the particle size of ZnO was the smallest. Furthermore, antimicrobial activities of ZnO, CA, and the mixtures of ZnO and CA were compared through the check... περισσότερα »
The influence of bone mineral density and bisphosphonate therapy on the determinants of oral health and changes on dental panoramic radiographs in postmenopausal women
Abstract Objectives The aim of this study was to assess the determinants of oral health including the number of decayed, missing, and filled teeth (DMFT) and periodontal indices in postmenopausal women with osteoporosis, osteoporosis treated with bisphosphonate therapy, and control group and to examine the correlation between dental panoramic indices (Mental Index—MI, Mandibular Cortical Index—MCI) and bone mineral density in these three groups of patients. Materials and methods The presented non-interventional study involved 120 postmenopausal women: women with osteoporosis (O) ...περισσότερα »
Expression of inducible nitric oxide synthase in mast cells contributes to the regulation of inflammatory cytokines in irritable bowel syndrome with diarrhea
Abstract Background Nitric oxide (NO) and mast cells (MCs) are possibly involved in the development of irritable bowel syndrome (IBS), but details on their role and interactions still remain undetermined. We aimed to investigate the expression of inducible NO synthase (iNOS) in MCs of the colon of IBS with diarrhea (IBS-D), and elucidated a potential role of NO in the differential regulation of cytokines in MCs. Methods Colonic mucosal biopsies of 19 IBS-D patients and 16 healthy controls were collected. The expression of tryptase and iNOS was investigated by immunohistochemistr... περισσότερα »
Depleted interstitial cells of Cajal and fibrosis in the pylorus: Novel features of gastroparesis
Abstract Background Depletion and ultrastructural changes of interstitial cells of Cajal (ICC) in the gastric body and antrum have been observed in gastroparesis. This research was performed to investigate the ICC population in the muscularis propria and fibrosis of the muscular layer of the pylorus in gastroparesis. Methods Full thickness pyloric and antral biopsies were obtained from 17 gastroparetic and 6 non-gastroparetic controls. Biopsies were stained with C-Kit for ICC and Trichrome for collagen fibrosis. Interstitial cells of Cajal depletion in the antrum was defined as m... περισσότερα »
Functional neuroimaging studies in functional dyspepsia patients: a systematic review
Abstract Background There is increasing evidence in support of the presence of abnormal central changes (compared to healthy controls) in functional dyspepsia (FD) in addition to the peripheral changes in gastrointestinal tract. Purpose This systematic review aims to provide an integrative understanding of the abnormal functional brain activity, visceral sensation, dyspeptic symptoms, and psychological changes of FD. Electronic and hand searches were conducted to identify functional neuroimaging studies involving FD patients. Sixteen studies were selected and divided into three c... περισσότερα »
A new alternative to cosmetics preservation and the effect of the particle size of the emulsion droplets on preservation efficacy
Abstract Objective This study describes a new alternative combination preservative containing caprylyl glycol, phenethyl alcohol, and glyceryl caprylate and investigates the effects of the particle size of the emulsion droplet on the antimicrobial activity of the said blend in the formulation. Methods The antimicrobial activity of the ingredients and the blend were determined via MIC, MBC, MFC, and fractional inhibitory concentration (FIC) determination using the broth microdilution method. The blend inhibited the microorganism contamination of the oil-in-water emulsion, and its ... περισσότερα »
Evaluation of antimicrobial activities of ZnO, citric acid, and a mixture of both against Propionibacterium acnes
Abstract Objective In this study, antimicrobial activities of ZnO of three different particle sizes, of citric acid (CA), and of mixtures of ZnO and CA were confirmed against *Propionibacterium acnes*. Methods ZnO with the smallest particle size showed relatively high antimicrobial activity by disc diffusion assay and broth macrodilution assay. The mixtures of ZnO and CA also showed relatively high antimicrobial activity when the particle size of ZnO was the smallest. Furthermore, antimicrobial activities of ZnO, CA, and the mixtures of ZnO and CA were compared through the check... περισσότερα »
Relation between sensory analysis and rheology of body lotions
Abstract Objective Evaluation of sensory attributes of cosmetic products is traditionally based on sensory panels. However, in some cases a suitable candidate method which can reduce time and costs is the use of instrumental analysis that can detect relatively very small changes of entry ingredients. Such approach has been already applied for emollients, salt content, stabilizers, etc. The aim of this contribution is to apply the relations between sensory analysis and rheology to a series of body lotions differing in the contents of emulsifiers and viscosity regulators. Methods ... περισσότερα »
Humoral deficiency in three paediatric patients with genetic diseases
Publication date: Available online 2 March 2016 *Source:*Allergologia et Immunopathologia Author(s): K. Calvo Campoverde, E. Gean, M. Piquer Gibert, L. Martinez Valdez, A. Deyà-Martínez, M. Rojas Volquez, A. Esteve-Sole, M. Juan, A.M. Plaza, L. Alsina BackgroundPrimary immunodeficiencies (PID) represent a heterogeneous group of genetic disorders characterised by poor or absent function in one or more components of the immune system. Humoral or antibody immunodeficiencies are the most common form of PID, of which common variable immunodeficiency (CVID) is the most frequent symptomati...περισσότερα »
Aeroallergen sensitivities and development of chronic rhinosinusitis in thirteen adults who initially had allergic rhinitis
Abstract Based on common comorbidity, immunologic mediators and symptomatology, there exist reported epidemiologic and pathophysiologic links between allergic rhinitis (AR) and chronic rhinosinusitis (CRS).1-3 In addition, AR has previously been associated with individuals who develop CRS.4 While it has previously been reported that obstructive sinonasal variants may be associated with the development of CRS in adults with AR5,6, the relationship between the degree of atopy and development of CRS in adults remains uncharacterized. This article is protected by copyright. All rights... περισσότερα »
Conventional and computer-aided design/computer-aided manufacturing wax patterns
Marginal and internal fit of pressed ceramic crowns made from conventional and computer-aided design/computer-aided manufacturing wax patterns: An in vitro comparison via The Journal of Prosthetic Dentistry Publication date: Available online 3 March 2016 *Source:*The Journal of Prosthetic Dentistry Author(s): Loubna Shamseddine, Rola Mortada, Khaldoun Rifai, Jose Johann Chidiac Statement of problemTo our knowledge, no studies have evaluated the influence of the wax fabrication technique on the internal adaptation and marginal accuracy of pressed ceramic single crowns.PurposeThe purpose...περισσότερα »
Scaffold-free parathyroid tissue engineering using tonsil-derived mesenchymal stem cells
Scaffold-free parathyroid tissue engineering using tonsil-derived mesenchymal stem cells via Acta Biomaterialia Publication date: Available online 2 March 2016 *Source:*Acta Biomaterialia Author(s): Yoon Shin Park, Ji-Young Hwang, Yesl Jun, Yoon Mi Jin, Gyungah Kim, Ha Yeong Kim, Han Su Kim, Sang-Hoon Lee, Inho Jo To restore damaged parathyroid function, parathyroid tissue engineering is the best option. Previously, we reported that differentiated tonsil-derived mesenchymal stem cells (dTMSC) restore in vivo parathyroid function, but only if they were embedded in a scaffold. Because of... περισσότερα »
Small molecule antiviral-loaded nanolipogels for HIV-1 chemoprophylaxis and topical mucosal application
Biophysical characterization of via Acta Biomaterialia Publication date: Available online 3 March 2016 *Source:*Acta Biomaterialia Author(s): R. Ramanathan, Y. Jiang, B. Read, S. Golan-Paz, K.A. Woodrow Nanocarriers are versatile vehicles for drug delivery, and emerging as platforms to formulate and deliver multiple classes of antiretroviral (ARV) drugs in a single system. Here we describe the fabrication of hydrogel-core and lipid-shell nanoparticles (nanolipogels) for the controlled loading and topical, vaginal delivery of maraviroc (MVC) and tenofovir disoproxil fumarate (TDF), two... περισσότερα »
Aeroallergen sensitivities and development of chronic rhinosinusitis in thirteen adults who initially had allergic rhinitis
Abstract Based on common comorbidity, immunologic mediators and symptomatology, there exist reported epidemiologic and pathophysiologic links between allergic rhinitis (AR) and chronic rhinosinusitis (CRS).1-3 In addition, AR has previously been associated with individuals who develop CRS.4 While it has previously been reported that obstructive sinonasal variants may be associated with the development of CRS in adults with AR5,6, the relationship between the degree of atopy and development of CRS in adults remains uncharacterized. This article is protected by copyright. All rights ... περισσότερα »
Post-thyroidectomy haemorrhage in a tertiary centre. Analysis of 1,280 operations and comparison to the BAETS audit 2012
Abstract Haemorrhage following thyroid surgery is an uncommon but potentially lethal complication, occurring in approximately 1% of all procedures, according to data submitted to the most recent audit, performed in 2012, by the British Association of Endocrine and Thyroid Surgeons (BAETS). This article is protected by copyright. All rights reserved. from #ORL-Sfakianakis via xlomafota13 on Inoreader http://ift.tt/1TdvrV7 via IFTTT
Retrospective study of the application of acellular dermis in reconstructing full-thickness skin defects
Abstract The purpose of the article is to evaluate the acellular dermis' utility in reconstructing full-thickness defects after scar contracture releasing and giant nevus resection. From the year 2012 to 2014, 18 consecutive patients underwent composite graft (thin autograft and alloderma) transplantation. Among these patients, 16 patients suffered from burned scar contracture in the upper extremities, and two young cases were met with giant nevus on the upper extremity. Ten of 13 adult cases with upper extremity scar affection were chosen for a comparative study. Twenty hands were ... περισσότερα »
Skin grafting for the treatment of chronic leg ulcers – a systematic review in evidence-based medicine
Abstract Skin grafting is one of the most common surgical procedures in the area of non-healing wounds by which skin or a skin substitute is placed over a wound to replace and regenerate the damaged skin. Chronic leg ulcers are an important problem and a major source of expense for Western countries and for which many different forms of treatment have been used. Skin grafting is a method of treatment that decreases the area of chronic leg ulcers or heals them completely, thus improving a patient's quality of life. Skin grafting is an old technique, rediscovered during the first and ... περισσότερα »
Interleukin-31 Receptor and Pruritus Associated with Primary Localized Cutaneous Amyloidosis
The study by Tey et al.1 examined the pathogenesis of itch in primary localized cutaneous amyloidosis (PLCA) and hypothesized that interleukin (IL)-31 is involved in itch transduction. Through immunohistochemical analysis of IL-31 and IL-31 receptor levels in patients versus controls, the authors concluded that antagonizing the IL-31 receptor could be therapeutic for treating itch in patients with PLCA. This article is protected by copyright. All rights reserved. from #ORL-Sfakianakis via xlomafota13 on Inoreader http://ift.tt/1TXxKKI via IFTTT
Vascular Anatomy and Clinical Application of the Free Proximal Ulnar Artery Perforator Flaps
[image: image]Background: There is a dearth of detailed published work on the anatomy of ulnar artery perforators. The objective of this study was to fully document the vascular basis of the free proximal ulnar artery perforator flap and report its use in reconstruction of the hand. Methods: (1) The ulnar artery perforators were studied in 25 fresh cadavers and 10 cast preparations. Cadavers were injected with lead oxide for 3-dimensional reconstruction. The origin, course, and distribution of the ulnar artery perforators were comprehensively documented. (2) Between August 2011 and ... περισσότερα »
Stable engineered vascular networks from human induced pluripotent stem cell-derived endothelial cells
cultured in synthetic hydrogels via Acta Biomaterialia Publication date: Available online 2 March 2016 *Source:*Acta Biomaterialia Author(s): Matthew R. Zanotelli, Hamisha Ardalani, Jue Zhang, Zhonggang Hou, Eric H. Nguyen, Scott Swanson, Bao Kim Nguyen, Jennifer Bolin, Angela Elwell, Lauren L. Bischel, Angela W. Xie, Ron Stewart, David J. Beebe, James A. Thomson, Michael P. Schwartz, William L. Murphy Here, we describe an in vitro strategy to model vascular morphogenesis where human induced pluripotent stem cell-derived endothelial cells (iPSC-ECs) are encapsulated in peptide-functio... περισσότερα »
Multilayered Polycaprolactone/Gelatin Fiber-Hydrogel Composite
for Tendon Tissue Engineering via Acta Biomaterialia Publication date: Available online 2 March 2016 *Source:*Acta Biomaterialia Author(s): Guang Yang, Hang Lin, Benjamin B. Rothrauff, Shuting Yu, Rocky S. Tuan Regeneration of injured tendon and ligament (T&L) remains a clinical challenge due to their poor intrinsic healing capacity. Tissue engineering provides a promising alternative treatment approach to facilitate T&L healing and regeneration. Successful tendon tissue engineering requires the use of three-dimensional (3D) biomimetic scaffolds that possess the physical and biochemi... περισσότερα »
Perinatal Thiamine Deficiency Causes Cochlear Innervation Abnormalities
in Mice via Hearing Research Publication date: Available online 2 March 2016 *Source:*Hearing Research Author(s): Stéphane F. Maison, Yanbo Yin, Leslie D. Liberman, M.Charles Liberman Neonatal thiamine deficiency can cause auditory neuropathy in humans. To probe the underlying cochlear pathology, mice were maintained on a thiamine-free or low-thiamine diet during fetal development or early postnatal life. At postnatal ages from 18 days to 22 wks, cochlear function was tested and cochlear histopathology analyzed by plastic sections and cochlear epithelial whole-mounts immunostained f...περισσότερα »
Effects of a consistent target or masker voice on target speech intelligibility in two- and three-talker mixtures
Effects of a consistent target or masker voice on target speech intelligibility in two- and three-talker mixtures: When the spatial location or identity of a sound is held constant, it is not masked as effectively by competing sounds. This suggests that experience with a particular voice over time might facilitate perceptual organization in multitalker environments. The current study examines whether listeners benefit from experience with a voice only when it is the target, or also when it is a masker, using diotic presentation and a closed-set task (coordinate response measure). A... περισσότερα »
Musician advantage for speech-on-speech perception
Musician advantage for speech-on-speech perception: Evidence for transfer of musical training to better perception of speech in noise has been mixed. Unlike speech-in-noise, speech-on-speech perception utilizes many of the skills that musical training improves, such as better pitch perception and stream segregation, as well as use of higher-level auditory cognitive functions, such as attention. Indeed, despite the few non-musicians who performed as well as musicians, on a group level, there was a strong musician benefit for speech perception in a speech masker. This benefit does no... περισσότερα »
Efficient Targeted Next Generation Sequencing-Based Workflow for Differential Diagnosis of Alport-Related Disorders
Efficient Targeted Next Generation Sequencing-Based Workflow for Differential Diagnosis of Alport-Related Disorders: by Gábor Kovács, Tibor Kalmár, Emőke Endreffy, Zoltán Ondrik, Béla Iványi, Csaba Rikker, Ibolya Haszon, Sándor Túri, Mária Sinkó, Csaba Bereczki, Zoltán Maróti Alport syndrome (AS) is an inherited type IV collagen nephropathies characterized by microscopic hematuria during early childhood, the development of proteinuria and progression to end-stage renal disease. Since choosing the right therapy, even before the onset of proteinuria, can delay the onset of end-stage... περισσότερα »
Congestion of mastoid mucosa and influence on middle ear pressure – effect of retroauricular injection of adrenaline
Congestion of mastoid mucosa and influence on middle ear pressure – effect of retroauricular injection of adrenaline via Hearing Research [image: S03785955.gif] Publication date: Available online 3 March 2016 *Source:*Hearing Research Author(s): Pernille Vita Fooken Jensen, Michael Gaihede Micro-CT scanning of temporal bones has revealed numerous retroauricular microchannels, which connect the outer bone surface directly to the underlying mastoid air cells. Their structure and dimensions have suggested a separate vascular supply to the mastoid mucosa, which may play a role in middle ... περισσότερα »
Noise Damage Without Hearing Loss
Noise Damage Without Hearing Loss: If you have occasional, regular or constant ringing in your ears, you are not alone. Up to 15 percent of American adults have this condition, and it has serious impacts on about 1 percent of the population. Tinnitus can make it hard to carry on a conversation, listen to a professor, watch television or conduct a meeting with your boss or colleagues. In most cases, tinnitus is related to damaged hearing without hearing loss. Audiograms and the Detection of Hearing Loss When a person has tinnitus, the first stop is often an audiologist’s office. An... περισσότερα »
The effects of frequency lowering on speech perception in noise with adult hearing-aid users
The effects of frequency lowering on speech perception in noise with adult hearing-aid users: 10.3109/14992027.2015.1137364<br>Christi W. Miller Abstract *Objective*: Frequency lowering (FL) strategies move high frequency sound into a lower frequency range. This study determined if speech perception differences are observed between some of the different frequency lowering strategies that are available. *Design*: A cross-sectional, repeated-measures design was used to compare three hearing aids that used wide-dynamic range compression (WDRC) and either non-linear frequency compress... περισσότερα »
A comparison between the Dutch and American-English digits-in-noise (DIN) tests in normal-hearing listeners
A comparison between the Dutch and American-English digits-in-noise (DIN) tests in normal-hearing listeners: 10.3109/14992027.2015.1137362<br>Cas Smits Abstract *Objective*: The Dutch digits-in-noise test (NL DIN) and the American-English version (US DIN) are speech-in-noise tests for diagnostic and clinical usage. The present study investigated differences between NL DIN and US DIN speech reception thresholds (SRTs) for a group of native Dutch-speaking listeners. *Design*: In experiment 1, a repeated-measures design was used to compare SRTs for the NL DIN and US DIN in steady-sta... περισσότερα »
Cochlear linear reconstruction with multidetector computed tomography
Cochlear linear reconstruction with multidetector computed tomography:
Post-thyroidectomy haemorrhage in a tertiary centre. Analysis of 1,280 operations and comparison to the BAETS audit 2012
Post-thyroidectomy haemorrhage in a tertiary centre. Analysis of 1,280 operations and comparison to the BAETS audit 2012: Abstract Haemorrhage following thyroid surgery is an uncommon but potentially lethal complication, occurring in approximately 1% of all procedures, according to data submitted to the most recent audit, performed in 2012, by the British Association of Endocrine and Thyroid Surgeons (BAETS). This article is protected by copyright. All rights reserved.
Aeroallergen sensitivities and development of chronic rhinosinusitis in thirteen adults who initially had allergic rhinitis
Aeroallergen sensitivities and development of chronic rhinosinusitis in thirteen adults who initially had allergic rhinitis: Abstract Based on common comorbidity, immunologic mediators and symptomatology, there exist reported epidemiologic and pathophysiologic links between allergic rhinitis (AR) and chronic rhinosinusitis (CRS).1-3 In addition, AR has previously been associated with individuals who develop CRS.4 While it has previously been reported that obstructive sinonasal variants may be associated with the development of CRS in adults with AR5,6, the relationship between the ... περισσότερα »
Engraftment and regenerative effects of bone marrow stromal cell transplantation on damaged rat olfactory mucosa
Engraftment and regenerative effects of bone marrow stromal cell transplantation on damaged rat olfactory mucosa: AbstractTo develop a new therapeutic method to treat olfactory deficits, we investigated the engraftment and regenerative effects of transplanted bone marrow stromal cells (BMSCs) on damaged rat olfactory mucosa. To induce olfactory nerve degeneration, one side of the olfactory mucosa of Sprague–Dawley rats was damaged via Triton X-100 irrigation. Phosphate-buffered saline containing syngeneic BMSCs was injected into the olfactory mucosa for transplantation. PKH fluores...περισσότερα »
Techniques of Human Embryonic Stem Cell and Induced Pluripotent Stem Cell Derivation
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 44 δευτερόλεπτα
Abstract Developing procedures for the derivation of human pluripotent stem cells (PSCs) gave rise to novel pathways into regenerative medicine research. For many years, stem cells have attracted attention as a potentially unlimited cell source for cellular therapy in neurodegenerative disorders, cardiovascular diseases, and spinal cord injuries, for example. In these studies, adult stem cells […]
Consumption of medicinal plants by patients with heart diseases at a pharmacist-managed anticoagulation clinic in Brazil
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 44 δευτερόλεπτα
Abstract Background Medicinal plants (MP) have been used for many years with the purpose of feeding and curing. Several MP may interfere in drug response and are not always considered as potential drug-interactors in clinical practice. Objective To investigate the consumption of MP by outpatients during a one-year follow-up. Method Patients with cardiopathy diagnosis and […]
Prix, contrats et bourses de recherche décernés par la Société française de médecine d’urgence en 2015
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 44 δευτερόλεπτα
from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1VV5sj1 via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
Atoms, Vol. 4, Pages 10: Relativistic Ionization of Hydrogen Atoms by Positron Impact
Relativistic triple differential cross-sections (TDCS) for ionization of hydrogen atoms by positron impact have been calculated in the symmetric coplanar geometry. We have used Dirac wave functions to describe free electron's and positron's sates. The relativistic formalism is examined by taking the non relativistic limit. Present results are compared with those for the corresponding electron-impact case. In the first Born approximation, we found that the TDCS for positron impact ionization exceeds that for electron impact for all energies in accordance with the result obtained by... περισσότερα »
Sports, Vol. 4, Pages 17: The Age in Swimming of Champions in World Championships (1994–2013) and Olympic Games (1992–2012): A Cross-Sectional Data Analysis
(1) Background: We investigated the age of swimming champions in all strokes and race distances in World Championships (1994–2013) and Olympic Games (1992–2012); (2) Methods: Changes in age and swimming performance across calendar years for 412 Olympic and world champions were analysed using linear, non-linear, multi-level regression analyses and MultiLayer Perceptron (MLP); (3) Results: The age of peak swimming performance remained stable in most of all race distances for world champions and in all race distances for Olympic champions. Longer (i.e., 200 m and more) race distances... περισσότερα »
Geosciences, Vol. 6, Pages 15: Stratigraphic Changes in the Pliocene Carnivoran Assemblage from Hagerman Fossil Beds National Monument, Idaho
At least 17 carnivoran taxa occur in the Pliocene Glenns Ferry Formation at Hagerman Fossil Beds National Monument (HAFO), Idaho. This assemblage was examined for stratigraphic changes in species distribution, specimen abundance, and species diversity. Three relatively common mustelids, Trigonictis cookii, Trigonictis macrodon, and Mustela rexroadensis, occur at most stratigraphic levels, but are absent during an interval coinciding with the coolest time segment at HAFO. It is within this gap that two less-common mustelids, Ferinestrix vorax and Buisnictis breviramus, first appear... περισσότερα »
Polymers, Vol. 8, Pages 74: Fabrication of Alkoxyamine-Functionalized Magnetic Core-Shell Microspheres via Reflux Precipitation Polymerization for Glycopeptide Enrichment
As a facile method to prepare hydrophilic polymeric microspheres, reflux precipitation polymerization has been widely used for preparation of polymer nanogels. In this article, we synthesized a phthalamide-protected N-aminooxy methyl acrylamide (NAMAm-p) for preparation of alkoxyamine-functionalized polymer composite microspheres via reflux precipitation polymerization. The particle size and functional group density of the composite microspheres could be adjusted by copolymerization with the second monomers, N-isopropyl acrylamide, acrylic acid or 2-hydroxyethyl methacrylate. The ...περισσότερα »
Materials, Vol. 9, Pages 169: Control of Magnetic Properties of NiMn2O4 by a Microwave Magnetic Field under Air
NiMn2O4 prepared by conventional heating was irradiated with a microwave H-field using a single-mode cavity under air and magnetic properties of the microwave-irradiated material were investigated. X-ray diffraction and transmission electron microscopy demonstrated that the phase and microstructure are not affected by H-field irradiation. Measurements of the magnetization as a function of temperature revealed that the antiferromagnetic sublattice disappeared and electron spin resonance showed the existence of Mn2+, suggesting that Mn3+ is partially reduced. Moreover, the magnetiza...περισσότερα »
Materials, Vol. 9, Pages 160: Preparation of a Microspherical Silver-Reduced Graphene Oxide-Bismuth Vanadate Composite and Evaluation of Its Photocatalytic Activity
A novel Ag-reduced graphene oxide (rGO)-bismuth vanadate (BiVO4) (AgGB) ternary composite was successfully synthesized via a one-step method. The prepared composite was characterized by X-ray diffraction (XRD), X-ray photoelectron spectroscopy (XPS), scanning electron microscopy (SEM), energy dispersive X-ray (EDX), Brunauer-Emmett-Teller (BET) surface area measurement, Raman scattering spectroscopy, and ultraviolet-visible diffuse-reflection spectroscopy (UV-vis DRS). The results showed that bulk monoclinic needle-like BiVO4 and Ag nanoparticles with a diameter of approximately 4... περισσότερα »
Label-free fluorescence detection of microRNA based on target induced adenosine2-coralyne-adenosine2 formation
[image: CrossMark.jpg] *Analyst*, 2016, Accepted Manuscript *DOI*: 10.1039/C6AN00001K, Communication Jun-Jie Li, Qiang Xi, Wen-Fang Du, Ruqin Yu, Jian-Hui Jiang This study develops a simple and label-free biosensor for sensitive and selective detection of microRNA (miRNA) based on the formation of adenosine2-coralyne-adenosine2 complex mediated by miRNA-specific polyadenosine extension. The content of this RSS Feed (c) The Royal Society of Chemistry from #Medicine via ola Kala on Inoreader http://ift.tt/21JdqTs via IFTTT
Recent advancements in ion concentration polarization
[image: CrossMark.jpg] *Analyst*, 2016, Accepted Manuscript *DOI*: 10.1039/C6AN00194G, Minireview Min Li, Robbyn Kimberly Anand In this mini review, we will discuss advancements in ion concentration polarization (ICP)-based preconcentration, separation, desalination, and dielectrophoresis that have been made over the past three years. ICP as a... The content of this RSS Feed (c) The Royal Society of Chemistry from #Medicine via ola Kala on Inoreader http://ift.tt/21JdoLj via IFTTT
Education Sciences, Vol. 6, Pages 8: “Way-Centered” versus “Truth-Centered” Epistemologies
In recent years, a criticism of "indigenous knowledge" has been that this idea makes sense only in terms of acquaintance (or familiarity) type and practical (or skills-type) knowledge (knowledge-how). Understood in terms of theoretical knowledge (or knowledge-that), however, it faces the arguably insurmountable problems of relativism and superstition. The educational implications of this would be that mere beliefs or opinions unanchored by reason(s), such as bald assertions, superstitions, prejudice and bias, should not be included in the curriculum, at least not under the guise o... περισσότερα »
Insects, Vol. 7, Pages 9: Pepper Weevil (Coleoptera: Curculionidae) Preferences for Specific Pepper Cultivars, Plant Parts, Fruit Colors, Fruit Sizes, and Timing
Peppers (Capsicum spp.) are an important crop in the USA, with about 32,000 ha cultivated in 2007, which resulted in $588 million in farm revenue. The pepper weevil, Anthonomus eugenii Cano (Coleoptera: Curculionidae), is the most troublesome insect pest of peppers in the southern United States. It is therefore urgent to find different vulnerabilities of pepper cultivars, fruit and plants parts, fruit colors and sizes, and timing to infestation by A. eugenii. Also relevant is testing whether fruit length and infestation state affect fruit numbers, weights, and proportions of fruit ... περισσότερα »
Polymers, Vol. 8, Pages 75: Polylactide/Montmorillonite Hybrid Latex as a Barrier Coating for Paper Applications
We developed a paper coating for the potential application in food packaging based on polylactide and montmorillonite. It is applied to the paper in the form of a stable, water-based latex with a solid content of 25–28 wt %. The latex is prepared from a commercially available polylactide, surfactants, montmorillonite, a plasticizer, chloroform (to be removed later) and water by an emulsion/solvent evaporation procedure. This coating formulation is applied to the paper substrate by bar-coating, followed by hot-pressing at 150 °C. The coated papers achieved up to an 85% improvement ... περισσότερα »
Polymers, Vol. 8, Pages 73: Polyelectrolyte Threading through a Nanopore
Threading charged polymers through a nanopore, driven by electric fields E, is investigated by means of Langevin dynamics simulations. The mean translocation time 〈 τ 〉 is shown to follow a scaling law Nα, and the exponent α increases monotonically from 1.16 (4) to 1.40 (3) with E. The result is double-checked by the calculation of mean square displacement of translocation coordinate, which asserts a scaling behavior tβ (for t near τ) with β complying with the relation αβ = 2. At a fixed chain length N, 〈τ〉 displayed a reciprocal scaling behavior E−1 in the weak and also in the st... περισσότερα »
Coordination of cell decisions and promotion of phenotypic diversity in B. subtilis via pulsed behavior of the phosphorelay
The phosphorelay of *Bacillus subtilis*, a kinase cascade that activates master regulator Spo0A ∼ P in response to starvation signals, is the core of a large network controlling the cell's decision to differentiate into sporulation and other phenotypes. This article reviews recent advances in understanding the origins and purposes of the complex dynamical behavior of the phosphorelay, which pulses with peaks of activity coordinated with the cell cycle. The transient imbalance in the expression of two critical genes caused by their strategic placement at opposing ends of the chromo... περισσότερα »
Comments on the Italian Society of Endocrinology recommendations on post-surgical thyroid ablation in differentiated thyroid cancer
from Endocrinology via ola Kala on Inoreader http://ift.tt/1VV3uiG via IFTTT
The analysis of blood pressure profiles and their severity in relation to diabetic cardiovascular autonomic neuropathy in the Chinese population: preliminary analysis
Abstract Background The study sought to investigate the associations of blood pressure profiles and its severity with diabetic cardiovascular autonomic neuropathy (DCAN) in a Chinese population. Methods We conducted a community-based, cross-sectional study for risk factor analysis of DCAN in 455 individuals recruited from a Chinese population. Blood pressure profile risk score (BPRS) was calculated for associations between severity of blood pressure profile and DCAN. Multivariable logistic regression (MLR) was carried out to analyze the associations of blood pressure profiles and...περισσότερα »
Reply to the Letter to the Editor by Sollini M et al.
from Endocrinology via ola Kala on Inoreader http://ift.tt/1VV3teE via IFTTT
Post-thyroidectomy haemorrhage in a tertiary centre. Analysis of 1,280 operations and comparison to the BAETS audit 2012
Abstract Haemorrhage following thyroid surgery is an uncommon but potentially lethal complication, occurring in approximately 1% of all procedures, according to data submitted to the most recent audit, performed in 2012, by the British Association of Endocrine and Thyroid Surgeons (BAETS). This article is protected by copyright. All rights reserved. from #ENT via xlomafota13 on Inoreader http://ift.tt/1TdvrV7 via IFTTT
Retrospective study of the application of acellular dermis in reconstructing full-thickness skin defects
Abstract The purpose of the article is to evaluate the acellular dermis' utility in reconstructing full-thickness defects after scar contracture releasing and giant nevus resection. From the year 2012 to 2014, 18 consecutive patients underwent composite graft (thin autograft and alloderma) transplantation. Among these patients, 16 patients suffered from burned scar contracture in the upper extremities, and two young cases were met with giant nevus on the upper extremity. Ten of 13 adult cases with upper extremity scar affection were chosen for a comparative study. Twenty hands were... περισσότερα »
Skin grafting for the treatment of chronic leg ulcers – a systematic review in evidence-based medicine
Abstract Skin grafting is one of the most common surgical procedures in the area of non-healing wounds by which skin or a skin substitute is placed over a wound to replace and regenerate the damaged skin. Chronic leg ulcers are an important problem and a major source of expense for Western countries and for which many different forms of treatment have been used. Skin grafting is a method of treatment that decreases the area of chronic leg ulcers or heals them completely, thus improving a patient's quality of life. Skin grafting is an old technique, rediscovered during the first and... περισσότερα »
Vascular Anatomy and Clinical Application of the Free Proximal Ulnar Artery Perforator Flaps
[image: image]Background: There is a dearth of detailed published work on the anatomy of ulnar artery perforators. The objective of this study was to fully document the vascular basis of the free proximal ulnar artery perforator flap and report its use in reconstruction of the hand. Methods: (1) The ulnar artery perforators were studied in 25 fresh cadavers and 10 cast preparations. Cadavers were injected with lead oxide for 3-dimensional reconstruction. The origin, course, and distribution of the ulnar artery perforators were comprehensively documented. (2) Between August 2011 and ... περισσότερα »
Relation between sensory analysis and rheology of body lotions
Abstract Objective Evaluation of sensory attributes of cosmetic products is traditionally based on sensory panels. However, in some cases a suitable candidate method which can reduce time and costs is the use of instrumental analysis that can detect relatively very small changes of entry ingredients. Such approach has been already applied for emollients, salt content, stabilizers, etc. The aim of this contribution is to apply the relations between sensory analysis and rheology to a series of body lotions differing in the contents of emulsifiers and viscosity regulators. Methods ... περισσότερα »
Humoral deficiency in three paediatric patients with genetic diseases
Publication date: Available online 2 March 2016 *Source:*Allergologia et Immunopathologia Author(s): K. Calvo Campoverde, E. Gean, M. Piquer Gibert, L. Martinez Valdez, A. Deyà-Martínez, M. Rojas Volquez, A. Esteve-Sole, M. Juan, A.M. Plaza, L. Alsina BackgroundPrimary immunodeficiencies (PID) represent a heterogeneous group of genetic disorders characterised by poor or absent function in one or more components of the immune system. Humoral or antibody immunodeficiencies are the most common form of PID, of which common variable immunodeficiency (CVID) is the most frequent symptomati...περισσότερα »
Aeroallergen sensitivities and development of chronic rhinosinusitis in thirteen adults who initially had allergic rhinitis
Abstract Based on common comorbidity, immunologic mediators and symptomatology, there exist reported epidemiologic and pathophysiologic links between allergic rhinitis (AR) and chronic rhinosinusitis (CRS).1-3 In addition, AR has previously been associated with individuals who develop CRS.4 While it has previously been reported that obstructive sinonasal variants may be associated with the development of CRS in adults with AR5,6, the relationship between the degree of atopy and development of CRS in adults remains uncharacterized. This article is protected by copyright. All rights... περισσότερα »
Post-thyroidectomy haemorrhage in a tertiary centre. Analysis of 1,280 operations and comparison to the BAETS audit 2012
Abstract Haemorrhage following thyroid surgery is an uncommon but potentially lethal complication, occurring in approximately 1% of all procedures, according to data submitted to the most recent audit, performed in 2012, by the British Association of Endocrine and Thyroid Surgeons (BAETS). This article is protected by copyright. All rights reserved. from #ENT via xlomafota13 on Inoreader http://ift.tt/1TdvrV7 via IFTTT
Retrospective study of the application of acellular dermis in reconstructing full-thickness skin defects
Abstract The purpose of the article is to evaluate the acellular dermis' utility in reconstructing full-thickness defects after scar contracture releasing and giant nevus resection. From the year 2012 to 2014, 18 consecutive patients underwent composite graft (thin autograft and alloderma) transplantation. Among these patients, 16 patients suffered from burned scar contracture in the upper extremities, and two young cases were met with giant nevus on the upper extremity. Ten of 13 adult cases with upper extremity scar affection were chosen for a comparative study. Twenty hands were... περισσότερα »
Depleted interstitial cells of Cajal and fibrosis in the pylorus: Novel features of gastroparesis
Abstract Background Depletion and ultrastructural changes of interstitial cells of Cajal (ICC) in the gastric body and antrum have been observed in gastroparesis. This research was performed to investigate the ICC population in the muscularis propria and fibrosis of the muscular layer of the pylorus in gastroparesis. Methods Full thickness pyloric and antral biopsies were obtained from 17 gastroparetic and 6 non-gastroparetic controls. Biopsies were stained with C-Kit for ICC and Trichrome for collagen fibrosis. Interstitial cells of Cajal depletion in the antrum was defined as m... περισσότερα »
Functional neuroimaging studies in functional dyspepsia patients: a systematic review
Abstract Background There is increasing evidence in support of the presence of abnormal central changes (compared to healthy controls) in functional dyspepsia (FD) in addition to the peripheral changes in gastrointestinal tract. Purpose This systematic review aims to provide an integrative understanding of the abnormal functional brain activity, visceral sensation, dyspeptic symptoms, and psychological changes of FD. Electronic and hand searches were conducted to identify functional neuroimaging studies involving FD patients. Sixteen studies were selected and divided into three c... περισσότερα »
Expression of inducible nitric oxide synthase in mast cells contributes to the regulation of inflammatory cytokines in irritable bowel syndrome with diarrhea
Abstract Background Nitric oxide (NO) and mast cells (MCs) are possibly involved in the development of irritable bowel syndrome (IBS), but details on their role and interactions still remain undetermined. We aimed to investigate the expression of inducible NO synthase (iNOS) in MCs of the colon of IBS with diarrhea (IBS-D), and elucidated a potential role of NO in the differential regulation of cytokines in MCs. Methods Colonic mucosal biopsies of 19 IBS-D patients and 16 healthy controls were collected. The expression of tryptase and iNOS was investigated by immunohistochemistry, ... περισσότερα »
Depleted interstitial cells of Cajal and fibrosis in the pylorus: Novel features of gastroparesis
Abstract Background Depletion and ultrastructural changes of interstitial cells of Cajal (ICC) in the gastric body and antrum have been observed in gastroparesis. This research was performed to investigate the ICC population in the muscularis propria and fibrosis of the muscular layer of the pylorus in gastroparesis. Methods Full thickness pyloric and antral biopsies were obtained from 17 gastroparetic and 6 non-gastroparetic controls. Biopsies were stained with C-Kit for ICC and Trichrome for collagen fibrosis. Interstitial cells of Cajal depletion in the antrum was defined as mean... περισσότερα »
Functional neuroimaging studies in functional dyspepsia patients: a systematic review
Abstract Background There is increasing evidence in support of the presence of abnormal central changes (compared to healthy controls) in functional dyspepsia (FD) in addition to the peripheral changes in gastrointestinal tract. Purpose This systematic review aims to provide an integrative understanding of the abnormal functional brain activity, visceral sensation, dyspeptic symptoms, and psychological changes of FD. Electronic and hand searches were conducted to identify functional neuroimaging studies involving FD patients. Sixteen studies were selected and divided into three cate... περισσότερα »
A comparison between the Dutch and American-English digits-in-noise (DIN) tests in normal-hearing listeners
10.3109/14992027.2015.1137362<br>Cas Smits from #Audiology via xlomafota13 on Inoreader http://ift.tt/1p44gjg via IFTTT
The effects of frequency lowering on speech perception in noise with adult hearing-aid users
10.3109/14992027.2015.1137364<br>Christi W. Miller from #Audiology via xlomafota13 on Inoreader http://ift.tt/1VV5Xti via IFTTT
A comparison between the Dutch and American-English digits-in-noise (DIN) tests in normal-hearing listeners
10.3109/14992027.2015.1137362<br>Cas Smits from #Audiology via ola Kala on Inoreader http://ift.tt/1p44gjg via IFTTT
The effects of frequency lowering on speech perception in noise with adult hearing-aid users
10.3109/14992027.2015.1137364<br>Christi W. Miller from #Audiology via ola Kala on Inoreader http://ift.tt/1VV5Xti via IFTTT
A comparison between the Dutch and American-English digits-in-noise (DIN) tests in normal-hearing listeners
10.3109/14992027.2015.1137362<br>Cas Smits from #Audiology via ola Kala on Inoreader http://ift.tt/1p44gjg via IFTTT
The effects of frequency lowering on speech perception in noise with adult hearing-aid users
10.3109/14992027.2015.1137364<br>Christi W. Miller from #Audiology via ola Kala on Inoreader http://ift.tt/1VV5Xti via IFTTT
A miniaturized fiber-optic colorimetric sensor for nitrite determination by coupling with a microfluidic capillary waveguide
Abstract A microfluidic-capillary-waveguide-coupled fiber-optic sensor was developed for colorimetric determination of hazardous nitrite based on the Griess–Ilosvay reaction. The sensor was modularly designed by use of a light-emitting diode as the light source, silica fiber as the light transmission element, and a capillary waveguide tube as the light reaction flow cell. With the light interacting with the azo dye generated by the Griess–Ilosvay reaction between nitrite and Griess reagents, nitrite could be determined by a colorimetric method according to Beer's law. By use of th... περισσότερα »
A GOP-level fuzzy rate control algorithm for high-delay applications of HEVC
Abstract The high -efficiency video coding (HEVC) standard was introduced for high-resolution video contents suitable for many high-delay applications. The bit rate of compressed video is controlled in almost all digital video applications according to the practical constraints such as available channel bandwidth and allowed delay or buffering constraint. In high-delay video applications such as video broadcasting and video streaming applications, variable-bit-rate videos can provide a higher visual quality than constant-bit-rate videos. In this paper, a rate control algorithm (RC... περισσότερα »
Simple and sensitive electrogenerated chemiluminescence peptide-based biosensor for detection of matrix metalloproteinase 2 released from living cells
Abstract A simple and sensitive electrogenerated chemiluminescence biosensor was developed to monitor matrix metalloproteinase 2 (MMP-2) by employing a specific peptide (CGPLGVRGK) as a molecular recognition substrate. Bis(2,2′-bipyridine)-4′-methyl-4-carboxybipyridine-ruthenium *N*-succinimidyl ester-bis(hexafluorophosphate) (Ru(bpy)2(mcbpy-O-Su-ester)(PF6)2 (Ru1) was used as ECL-emitting species and covalently labeled onto the peptide through NH2-containing lysine on the peptide via acylation reaction to form Ru1-peptide as an ECL probe. An ECL peptide-based biosensor was fabrica... περισσότερα »
High veno-arterial carbon dioxide gradient is not predictive of worst outcome after an elective cardiac surgery: a retrospective cohort study
Abstract Alteration of tissue perfusion is a main contributor of organ dysfunction. In cardiac surgery, the importance of organ dysfunction is associated with worse outcome. Central venous-arterial difference in CO2 tension (ΔCO2) has been proposed as a global marker of the adequacy of tissue perfusion in shock states. We hypothesized that ΔCO2 could be increased in case of postoperative organ failure or worse outcome. In this monocentric retrospective cohort study, we retrieved, from our database, 220 consecutive patients admitted in intensive care after an elective cardiac surge... περισσότερα »
Cell-Demanded VEGF Release via Nanocapsules Elicits Different Receptor Activation Dynamics and Enhanced Angiogenesis
Abstract Although the delivery of vascular endothelial growth factor (VEGF) with extended release profiles has consistently shown beneficial therapeutic effects compared with bolus delivery, [Martino, M. M., F. Tortelli, M. Mochizuki, S. Traub, D. Ben-David, G. A. Kuhn, R. Muller, E. Livne, S. A. Eming, and J. A. Hubbell. *Sci. Transl. Med.* 3(100):100ra189, 2011; Martino, M. M., P. S. Briquez, A. Ranga, M. P. Lutolf, and J. A. Hubbell. *Proc. Natl. Acad. Sci. USA*. 110(12):4563–4568, 2013; Amiram, M., K. M. Luginbuhl, X. Li, M. N. Feinglos, and A. Chilkoti. *Proc. Natl. Acad. Sci.... περισσότερα »
Jill Swing: Time For South Carolina To Legalize Medical Cannabis – FITSNews
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Jill Swing: Time For South Carolina To Legalize Medical Cannabis FITSNews While the Senate is discussing potholes and new road projects, somewhere in our state someone’s child is having a life-threatening seizure, someone’s sister is losing her battle with cancer and another veteran with PTSD will put a gun to his head and … from […]
Brain structure in autism: a voxel-based morphometry analysis of the Autism Brain Imaging Database Exchange (ABIDE)
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Abstract Increased brain volume is a consistent finding in young children with autism spectrum disorders (ASD); however, the regional specificity and developmental course of abnormal brain structure are less clear. Small sample sizes, particularly among voxel-based morphometry (VBM) investigations, likely contribute to this difficulty. Recently established large-scale neuroimaging data repositories have helped clarify the neuroanatomy […]
Assessment of cryopreserved donor skin viability: the experience of the regional tissue bank of Siena
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Abstract Skin allografts from cadaver donors are an important resource for treating extensive burns, slow-healing wounds and chronic ulcers. A high level of cell viability of cryopreserved allografts is often required, especially in burn surgery, in Italy. Thus, we aimed to determine which conditions enable procurement of highly viable skin in our Regional Skin Bank […]
Societal Preferences for Interventions with the Same Efficiency: Assessment and Application to Decision Making
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Abstract Background and Objectives Although quality-adjusted life-years (QALYs) may not completely reflect the value of a healthcare technology, it remains unclear how to adjust the cost per QALY threshold. First, the present study compares two survey methods of measuring people’s preferences for a specific healthcare technology when each choice has the same efficiency. The second […]
Use of fluorescent proteins and color-coded imaging to visualize cancer cells with different genetic properties
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Abstract Fluorescent proteins are very bright and available in spectrally-distinct colors, enable the imaging of color-coded cancer cells growing in vivo and therefore the distinction of cancer cells with different genetic properties. Non-invasive and intravital imaging of cancer cells with fluorescent proteins allows the visualization of distinct genetic variants of cancer cells down to the […]
Does telomere length predict decline in physical functioning in older twin sisters during an 11-year follow-up?
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Abstract Leukocyte telomere length (LTL) is known to be associated with mortality, but its association with age-related decline in physical functioning and the development of disability is less clear. This study examined the associations between LTL and physical functioning, and investigated whether LTL predicts level of physical functioning over an 11-year follow-up. Older mono- (MZ) […]
Chordoma: The Quest for Better Treatment Options
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Abstract Chordoma is an extremely rare cancer, with an incidence of about one case per million persons per year in the USA and Europe (about 300 and 450 cases per year, respectively). The estimated median overall survival of patients with chordoma is approximately 6–7 years, yielding a rough estimate of chordoma prevalence at about 2000 […]
Adhesive Properties and Acid-Forming Activity of Lactobacilli and Streptococci Under Inhibitory Substances, Such as Nitrates
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Abstract One of the main requirements for probiotics is their ability to survive during passage through gastrointestinal tract and to maintain their activity at different adverse conditions. The aim of the study was to look for the strains of lactobacilli and streptococci with high adhesive properties even affected by inhibitory substances, such as nitrates (NO3−). […]
Survey of Ebola Preparedness in Washington State Emergency Departments
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Research Articles C. Hayes Wong, Susan Stern, Steven H. Mitchell Disaster Medicine and Public Health Preparedness,FirstView Article(s), 7 pages Abstract from #AlexandrosSfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1TXIKHO via IFTTT
Disaster Radio for Communication of Vital Messages and Health-Related Information: Experiences From the Haiyan Typhoon, the Philippines
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Research Articles Karin Hugelius, Mervyn Gifford, Per Örtenwall, Annsofie Adolfsson Disaster Medicine and Public Health Preparedness,FirstView Article(s), 7 pages Abstract from #AlexandrosSfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1TXIJDY via IFTTT
Oscillations, Timing, Plasticity, and Learning in the Cerebellum
Abstract The highly stereotyped, crystal-like architecture of the cerebellum has long served as a basis for hypotheses with regard to the function(s) that it subserves. Historically, most clinical observations and experimental work have focused on the involvement of the cerebellum in motor control, with particular emphasis on coordination and learning. Two main models have been… Continue reading Oscillations, Timing, Plasticity, and Learning in the Cerebellum
IJERPH, Vol. 13, Pages 288: E-Cigarettes for Immediate Smoking Substitution in Women Diagnosed with Cervical Dysplasia and Associated Disorders
The aim of this study was to determine if 31 women with cervical dysplasia and associated conditions exacerbated by smoking would be successful substituting cigarettes with their choice of either nicotine replacement therapy (NRT) or electronic cigarettes (EC). Women received motivational interviewing and tried both NRT and ECs, choosing one method to use during a… Continue reading IJERPH, Vol. 13, Pages 288: E-Cigarettes for Immediate Smoking Substitution in Women Diagnosed with Cervical Dysplasia and Associated Disorders
Consumption of medicinal plants by patients with heart diseases at a pharmacist-managed anticoagulation clinic in Brazil
Abstract Background Medicinal plants (MP) have been used for many years with the purpose of feeding and curing. Several MP may interfere in drug response and are not always considered as potential drug-interactors in clinical practice. Objective To investigate the consumption of MP by outpatients during a one-year follow-up. Method Patients with cardiopathy diagnosis and… Continue reading Consumption of medicinal plants by patients with heart diseases at a pharmacist-managed anticoagulation clinic in Brazil
Prix, contrats et bourses de recherche décernés par la Société française de médecine d’urgence en 2015
from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1VV5sj1 via IFTTT
Cerebellar Synaptic Plasticity and the Credit Assignment Problem
Abstract The mechanism by which a learnt synaptic weight change can contribute to learning or adaptation of brain function is a type of credit assignment problem, which is a key issue for many parts of the brain. In the cerebellum, detailed knowledge not only of the local circuitry connectivity but also of the topography of… Continue reading Cerebellar Synaptic Plasticity and the Credit Assignment Problem
Read our latest clinical study on #dabrafenib in metastatic melanoma: a monocentric ‘real life’ experi ence https://t.co/aSkBWZM5Rc
Read our latest clinical study on #dabrafenib in metastatic melanoma: a monocentric ‘real life’ experience https://t.co/aSkBWZM5Rc from #ORL-AlexandrosSfakianakis via simeraentaxei on Inoreader http://twitter.com/ecancer/status/705685484056539137 via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174 from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1UEekv5 via IFTTT
Ponction et infiltration articulaire du genou
Résumé La ponction articulaire du genou est un geste technique simple, rapide et peu invasif de pratique courante aux urgences. Ses indications sont nombreuses, et elle est réalisée aussi bien à visée diagnostique (aspect visuel et analyse biologique du liquide articulaire) que thérapeutique (évacuation d’un épanchement septique ou sous tension et parfois infiltration médicamenteuse). Il… Continue reading Ponction et infiltration articulaire du genou
Manifestations cardiovasculaires de l’intoxication cyanhydrique aiguë
Résumé Longtemps méconnue, l’intoxication cyanhydrique survient le plus souvent lors d’inhalation accidentelle de fumées d’incendie. Au niveau cellulaire, le cyanure se fixe en inhibant le cytochrome oxydase mitochondrial, ce qui entraîne un arrêt de la consommation d’oxygène avec déviation du métabolisme vers un mode anaérobie. À côté des signes cliniques respiratoires et neurologiques classiques, l’épidémiologie… Continue reading Manifestations cardiovasculaires de l’intoxication cyanhydrique aiguë
Chronic liquid nutrition intake induces obesity and considerable but reversible metabolic alterations in Wistar rats
Abstract We have previously described the development of substantial, but reversible obesity in Wistar rats fed with palatable liquid nutrition (Fresubin). In this study, we investigated changes in serum hormone levels, glycemia, fat mass, adipocyte size, and gene expression of adipokines and inflammatory markers in adipose tissue of Wistar rats fed by Fresubin (i) for… Continue reading Chronic liquid nutrition intake induces obesity and considerable but reversible metabolic alterations in Wistar rats
Toxins, Vol. 8, Pages 65: Conversion Ratio between Botox®, Dysport®, and Xeomin® in Clinical Practi ce
Botulinum neurotoxin has revolutionized the treatment of spasticity and is now administered worldwide. There are currently three leading botulinum neurotoxin type A products available in the Western Hemisphere: onabotulinum toxin-A (ONA) Botox®, abobotulinum toxin-A (ABO), Dysport®, and incobotulinum toxin A (INCO, Xeomin®). Although the efficacies are similar, there is an intense debate regarding the comparability… Continue reading Toxins, Vol. 8, Pages 65: Conversion Ratio between Botox®, Dysport®, and Xeomin® in Clinical Practi ce
Adhesive Properties and Acid-Forming Activity of Lactobacilli and Streptococci Under Inhibitory Substances, Such as Nitrates
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 1 ώρα
Abstract One of the main requirements for probiotics is their ability to survive during passage through gastrointestinal tract and to maintain their activity at different adverse conditions. The aim of the study was to look for the strains of lactobacilli and streptococci with high adhesive properties even affected by inhibitory substances, such as nitrates (NO3−). […]
Survey of Ebola Preparedness in Washington State Emergency Departments
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 1 ώρα
Research Articles C. Hayes Wong, Susan Stern, Steven H. Mitchell Disaster Medicine and Public Health Preparedness,FirstView Article(s), 7 pages Abstract from #ORL-AlexandrosSfakianakis via simeraentaxei on Inoreader http://ift.tt/1TXIKHO via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
Disaster Radio for Communication of Vital Messages and Health-Related Information: Experiences From the Haiyan Typhoon, the Philippines
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 1 ώρα
Research Articles Karin Hugelius, Mervyn Gifford, Per Örtenwall, Annsofie Adolfsson Disaster Medicine and Public Health Preparedness,FirstView Article(s), 7 pages Abstract from #ORL-AlexandrosSfakianakis via simeraentaxei on Inoreader http://ift.tt/1TXIJDY via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
Consensus Paper: Neuroimmune Mechanisms of Cerebellar Ataxias
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 1 ώρα
Abstract In the last few years, a lot of publications suggested that disabling cerebellar ataxias may develop through immune-mediated mechanisms. In this consensus paper, we discuss the clinical features of the main described immune-mediated cerebellar ataxias and address their presumed pathogenesis. Immune-mediated cerebellar ataxias include cerebellar ataxia associated with anti-GAD antibodies, the cerebellar type of […]
Heterozygous Deletion of KLHL1/ATX8OS at the SCA8 Locus Is Unlikely Associated With Cerebellar Impairment in Humans
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 1 ώρα
from #ORL-AlexandrosSfakianakis via simeraentaxei on Inoreader http://ift.tt/1UEe66Y via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
Asymmetries in Cerebellar Plasticity and Motor Learning
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 1 ώρα
Abstract Synaptic plasticity at the parallel fiber to Purkinje cell synapse has long been considered a cellular correlate for cerebellar motor learning. Functionally, long-term depression and long-term potentiation at these synapses seem to be the reverse of each other, with both pre- and post-synaptic expression occurring in both. However, different cerebellar motor learning paradigms have […]
Synaptic Multivesicular Release in the Cerebellar Cortex: Its Mechanism and Role in Neural Encoding and Processing
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 1 ώρα
Abstract The number of synaptic vesicles released during fast release plays a major role in determining the strength of postsynaptic response. However, it remains unresolved how the number of vesicles released in response to action potentials is controlled at a single synapse. Recent findings suggest that the Cav2.1 subtype (P/Q-type) of voltage-gated calcium channels is […]
Oscillations, Timing, Plasticity, and Learning in the Cerebellum
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 1 ώρα
Abstract The highly stereotyped, crystal-like architecture of the cerebellum has long served as a basis for hypotheses with regard to the function(s) that it subserves. Historically, most clinical observations and experimental work have focused on the involvement of the cerebellum in motor control, with particular emphasis on coordination and learning. Two main models have been […]
Cerebellar Synaptic Plasticity and the Credit Assignment Problem
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 1 ώρα
Abstract The mechanism by which a learnt synaptic weight change can contribute to learning or adaptation of brain function is a type of credit assignment problem, which is a key issue for many parts of the brain. In the cerebellum, detailed knowledge not only of the local circuitry connectivity but also of the topography of […]
Read our latest clinical study on #dabrafenib in metastatic melanoma: a monocentric ‘real life’ experi ence https://t.co/aSkBWZM5Rc
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 1 ώρα
Read our latest clinical study on #dabrafenib in metastatic melanoma: a monocentric ‘real life’ experience https://t.co/aSkBWZM5Rc from #ORL-AlexandrosSfakianakis via simeraentaxei on Inoreader http://twitter.com/ecancer/status/705685484056539137 via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
Transfusion of 35-Day Stored RBCs in the Presence of Endotoxemia Does Not Result in Lung Injury in Humans.
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Objective: Transfusion-related acute lung injury is the leading cause of transfusion-related mortality. Preclinical studies have shown that aged RBCs can induce transfusion-related acute lung injury in the presence of a «first hit» (e.g., sepsis). Clinical studies, however, show conflicting results on this matter. We tested whether maximally stored RBCs are able to induce lung injury […]
Beneficial Effects of Early Enteral Nutrition After Major Rectal Surgery: A Possible Role for Conditionally Essential Amino Acids? Results of a Randomized Clinical Trial.
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Objectives: To investigate direct postoperative outcome and plasma amino acid concentrations in a study comparing early enteral nutrition versus early parenteral nutrition after major rectal surgery. Previously, it was shown that a low plasma glutamine concentration represents poor prognosis in ICU patients. Design: A preplanned substudy of a previous prospective, randomized, open-label, single-centre study, comparing […]
Diagnostics, Vol. 6, Pages 13: Auto Diagnostics of Lung Nodules Using Minimal Characteristics Extraction Technique
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Computer-aided detection (CAD) systems provide useful tools and an advantageous process to physicians aiming to detect lung nodules. This paper develops a method composed of four processes for lung nodule detection. The first step employs image acquisition and pre-processing techniques to isolate the lungs from the rest of the body. The second stage involves the […]
Schönheitsspritze kann unschöne Folgen haben
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Unerwünschte Fillerreaktionen Der Effekt von Fillerinjektionen fällt manchmal anders aus als beabsichtigt: Statt Falten zu korrigieren werden Sorgenfalten noch vermehrt. Die Lebensqualität kann darunter erheblich leiden. from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1LXWxYF via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
Variations in Case-Mix-Adjusted Duration of Mechanical Ventilation Among ICUs.
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Objectives: To develop a model that predicts the duration of mechanical ventilation and then to use this model to compare observed versus expected duration of mechanical ventilation across ICUs. Design: Retrospective cohort analysis. Setting: Eighty-six eligible ICUs at 48 U.S. hospitals. Patients: ICU patients receiving mechanical ventilation on day 1 (n = 56,336) admitted from […]
Impact of Proactive Nurse Participation in ICU Family Conferences: A Mixed-Method Study.
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Objectives: To investigate family perceptions of having a nurse participating in family conferences and to assess the psychologic well being of the same families after ICU discharge. Design: Mixed-method design with a qualitative study embedded in a single-center randomized study. Setting: Twelve-bed medical-surgical ICU in a 460-bed tertiary hospital. Subjects: One family member for each […]
Growing Up After Critical Illness: Verbal, Visual-Spatial, and Working Memory Problems in Neonatal Extracorporeal Membrane Oxygenation Survivors.
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Objectives: To assess neuropsychologic outcome in 17- and 18-year-old neonatal extracorporeal membrane oxygenation survivors. Design: A prospective longitudinal follow-up study. Setting: Follow-up program at the Erasmus MC-Sophia Children’s Hospital in Rotterdam, The Netherlands. Patients: Thirty adolescents 17 or 18 years old, treated between 1991 and 1997, underwent neuropsychologic assessment. Interventions: None. Measurements and Main Results: […]
Evaluation of Noninvasive Hemoglobin Monitoring in Surgical Critical Care Patients.
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Objective: To assess the clinical utility of noninvasive hemoglobin monitoring based on pulse cooximetry in the ICU setting. Design and Setting: A total of 358 surgical patients from a large urban, academic hospital had the noninvasive hemoglobin monitoring pulse cooximeter placed at admission to the ICU. Core and stat laboratory hemoglobin measurements were taken at […]
Transfusion of 35-Day Stored RBCs in the Presence of Endotoxemia Does Not Result in Lung Injury in Humans.
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Objective: Transfusion-related acute lung injury is the leading cause of transfusion-related mortality. Preclinical studies have shown that aged RBCs can induce transfusion-related acute lung injury in the presence of a «first hit» (e.g., sepsis). Clinical studies, however, show conflicting results on this matter. We tested whether maximally stored RBCs are able to induce lung injury […]
Beneficial Effects of Early Enteral Nutrition After Major Rectal Surgery: A Possible Role for Conditionally Essential Amino Acids? Results of a Randomized Clinical Trial.
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Objectives: To investigate direct postoperative outcome and plasma amino acid concentrations in a study comparing early enteral nutrition versus early parenteral nutrition after major rectal surgery. Previously, it was shown that a low plasma glutamine concentration represents poor prognosis in ICU patients. Design: A preplanned substudy of a previous prospective, randomized, open-label, single-centre study, comparing […]
Skin grafting for the treatment of chronic leg ulcers – a systematic review in evidence-based medicine
Abstract Skin grafting is one of the most common surgical procedures in the area of non-healing wounds by which skin or a skin substitute is placed over a wound to replace and regenerate the damaged skin. Chronic leg ulcers are an important problem and a major source of expense for Western countries and for which many different forms of treatment have been used. Skin grafting is a method of treatment that decreases the area of chronic leg ulcers or heals them completely, thus improving a patient's quality of life. Skin grafting is an old technique, rediscovered during the first and... περισσότερα »
Vascular Anatomy and Clinical Application of the Free Proximal Ulnar Artery Perforator Flaps
[image: image]Background: There is a dearth of detailed published work on the anatomy of ulnar artery perforators. The objective of this study was to fully document the vascular basis of the free proximal ulnar artery perforator flap and report its use in reconstruction of the hand. Methods: (1) The ulnar artery perforators were studied in 25 fresh cadavers and 10 cast preparations. Cadavers were injected with lead oxide for 3-dimensional reconstruction. The origin, course, and distribution of the ulnar artery perforators were comprehensively documented. (2) Between August 2011 and ... περισσότερα »
The Impact of Sleep Timing, Sleep Duration, and Sleep Quality on Depressive Symptoms and Suicidal Ideation amongst Japanese Freshmen: The EQUSITE Study
Aim. The aim of this study was to identify the impact of bedtime, wake time, sleep duration, sleep-onset latency, and sleep quality on depressive symptoms and suicidal ideation amongst Japanese freshmen. Methods. This cross-sectional data was derived from the baseline survey of the Enhancement of Q-University Students Intelligence (EQUSITE) study conducted from May to June, 2010. A total of 2,631 participants were recruited and completed the following self-reported questionnaires: the Pittsburgh Sleep Quality Index (PSQI), the Center for Epidemiologic Studies Depression Scale (CES... περισσότερα »
Expression of inducible nitric oxide synthase in mast cells contributes to the regulation of inflammatory cytokines in irritable bowel syndrome with diarrhea
Abstract Background Nitric oxide (NO) and mast cells (MCs) are possibly involved in the development of irritable bowel syndrome (IBS), but details on their role and interactions still remain undetermined. We aimed to investigate the expression of inducible NO synthase (iNOS) in MCs of the colon of IBS with diarrhea (IBS-D), and elucidated a potential role of NO in the differential regulation of cytokines in MCs. Methods Colonic mucosal biopsies of 19 IBS-D patients and 16 healthy controls were collected. The expression of tryptase and iNOS was investigated by immunohistochemistr... περισσότερα »
Depleted interstitial cells of Cajal and fibrosis in the pylorus: Novel features of gastroparesis
Abstract Background Depletion and ultrastructural changes of interstitial cells of Cajal (ICC) in the gastric body and antrum have been observed in gastroparesis. This research was performed to investigate the ICC population in the muscularis propria and fibrosis of the muscular layer of the pylorus in gastroparesis. Methods Full thickness pyloric and antral biopsies were obtained from 17 gastroparetic and 6 non-gastroparetic controls. Biopsies were stained with C-Kit for ICC and Trichrome for collagen fibrosis. Interstitial cells of Cajal depletion in the antrum was defined as m... περισσότερα »
Functional neuroimaging studies in functional dyspepsia patients: a systematic review
Abstract Background There is increasing evidence in support of the presence of abnormal central changes (compared to healthy controls) in functional dyspepsia (FD) in addition to the peripheral changes in gastrointestinal tract. Purpose This systematic review aims to provide an integrative understanding of the abnormal functional brain activity, visceral sensation, dyspeptic symptoms, and psychological changes of FD. Electronic and hand searches were conducted to identify functional neuroimaging studies involving FD patients. Sixteen studies were selected and divided into three c... περισσότερα »
A new alternative to cosmetics preservation and the effect of the particle size of the emulsion droplets on preservation efficacy
Abstract Objective This study describes a new alternative combination preservative containing caprylyl glycol, phenethyl alcohol, and glyceryl caprylate and investigates the effects of the particle size of the emulsion droplet on the antimicrobial activity of the said blend in the formulation. Methods The antimicrobial activity of the ingredients and the blend were determined via MIC, MBC, MFC, and fractional inhibitory concentration (FIC) determination using the broth microdilution method. The blend inhibited the microorganism contamination of the oil-in-water emulsion, and its ... περισσότερα »
Evaluation of antimicrobial activities of ZnO, citric acid, and a mixture of both against Propionibacterium acnes
Abstract Objective In this study, antimicrobial activities of ZnO of three different particle sizes, of citric acid (CA), and of mixtures of ZnO and CA were confirmed against *Propionibacterium acnes*. Methods ZnO with the smallest particle size showed relatively high antimicrobial activity by disc diffusion assay and broth macrodilution assay. The mixtures of ZnO and CA also showed relatively high antimicrobial activity when the particle size of ZnO was the smallest. Furthermore, antimicrobial activities of ZnO, CA, and the mixtures of ZnO and CA were compared through the check... περισσότερα »
Relation between sensory analysis and rheology of body lotions
Abstract Objective Evaluation of sensory attributes of cosmetic products is traditionally based on sensory panels. However, in some cases a suitable candidate method which can reduce time and costs is the use of instrumental analysis that can detect relatively very small changes of entry ingredients. Such approach has been already applied for emollients, salt content, stabilizers, etc. The aim of this contribution is to apply the relations between sensory analysis and rheology to a series of body lotions differing in the contents of emulsifiers and viscosity regulators. Methods ... περισσότερα »
Humoral deficiency in three paediatric patients with genetic diseases
Publication date: Available online 2 March 2016 *Source:*Allergologia et Immunopathologia Author(s): K. Calvo Campoverde, E. Gean, M. Piquer Gibert, L. Martinez Valdez, A. Deyà-Martínez, M. Rojas Volquez, A. Esteve-Sole, M. Juan, A.M. Plaza, L. Alsina BackgroundPrimary immunodeficiencies (PID) represent a heterogeneous group of genetic disorders characterised by poor or absent function in one or more components of the immune system. Humoral or antibody immunodeficiencies are the most common form of PID, of which common variable immunodeficiency (CVID) is the most frequent symptomati...περισσότερα »
Aeroallergen sensitivities and development of chronic rhinosinusitis in thirteen adults who initially had allergic rhinitis
Abstract Based on common comorbidity, immunologic mediators and symptomatology, there exist reported epidemiologic and pathophysiologic links between allergic rhinitis (AR) and chronic rhinosinusitis (CRS).1-3 In addition, AR has previously been associated with individuals who develop CRS.4 While it has previously been reported that obstructive sinonasal variants may be associated with the development of CRS in adults with AR5,6, the relationship between the degree of atopy and development of CRS in adults remains uncharacterized. This article is protected by copyright. All rights... περισσότερα »
Post-thyroidectomy haemorrhage in a tertiary centre. Analysis of 1,280 operations and comparison to the BAETS audit 2012
Abstract Haemorrhage following thyroid surgery is an uncommon but potentially lethal complication, occurring in approximately 1% of all procedures, according to data submitted to the most recent audit, performed in 2012, by the British Association of Endocrine and Thyroid Surgeons (BAETS). This article is protected by copyright. All rights reserved. from #ENT via xlomafota13 on Inoreader http://ift.tt/1TdvrV7 via IFTTT
Retrospective study of the application of acellular dermis in reconstructing full-thickness skin defects
Abstract The purpose of the article is to evaluate the acellular dermis' utility in reconstructing full-thickness defects after scar contracture releasing and giant nevus resection. From the year 2012 to 2014, 18 consecutive patients underwent composite graft (thin autograft and alloderma) transplantation. Among these patients, 16 patients suffered from burned scar contracture in the upper extremities, and two young cases were met with giant nevus on the upper extremity. Ten of 13 adult cases with upper extremity scar affection were chosen for a comparative study. Twenty hands were... περισσότερα »
Skin grafting for the treatment of chronic leg ulcers – a systematic review in evidence-based medicine
Abstract Skin grafting is one of the most common surgical procedures in the area of non-healing wounds by which skin or a skin substitute is placed over a wound to replace and regenerate the damaged skin. Chronic leg ulcers are an important problem and a major source of expense for Western countries and for which many different forms of treatment have been used. Skin grafting is a method of treatment that decreases the area of chronic leg ulcers or heals them completely, thus improving a patient's quality of life. Skin grafting is an old technique, rediscovered during the first and... περισσότερα »
Working to combat Zika
Alexandros G. SfakianakisστοOnline Journals of Otolaryngology Head and Neck Surgery by Alexandros G.SfakianakisΠριν από 1 ώρα
Advertisment [image: BioMed Central – The Open Access Publisher] BMC Update BioMed Central Update Featured news and updates Working to combat Zika Zika virus has been declared a global health emergency following an outbreak detected in Brazil last year. All BioMed Central articles (for example this one, published in *BMC Infectious Diseases*) are free to read and can be easily accessed by policymakers, clinicians, those working in developing countries and the general public. In addition to this, our parent company, Springer Nature has joined a global pledge by top rese... περισσότερα »
Expression of inducible nitric oxide synthase in mast cells contributes to the regulation of inflammatory cytokines in irritable bowel syndrome with diarrhea
Abstract Background Nitric oxide (NO) and mast cells (MCs) are possibly involved in the development of irritable bowel syndrome (IBS), but details on their role and interactions still remain undetermined. We aimed to investigate the expression of inducible NO synthase (iNOS) in MCs of the colon of IBS with diarrhea (IBS-D), and elucidated a potential role of NO in the differential regulation of cytokines in MCs. Methods Colonic mucosal biopsies of 19 IBS-D patients and 16 healthy controls were collected. The expression of tryptase and iNOS was investigated by immunohistochemistr... περισσότερα »
Diagnostics, Vol. 6, Pages 13: Auto Diagnostics of Lung Nodules Using Minimal Characteristics Extraction Technique
Computer-aided detection (CAD) systems provide useful tools and an advantageous process to physicians aiming to detect lung nodules. This paper develops a method composed of four processes for lung nodule detection. The first step employs image acquisition and pre-processing techniques to isolate the lungs from the rest of the body. The second stage involves the… Continue reading Diagnostics, Vol. 6, Pages 13: Auto Diagnostics of Lung Nodules Using Minimal Characteristics Extraction Technique
Schönheitsspritze kann unschöne Folgen haben
Unerwünschte Fillerreaktionen Der Effekt von Fillerinjektionen fällt manchmal anders aus als beabsichtigt: Statt Falten zu korrigieren werden Sorgenfalten noch vermehrt. Die Lebensqualität kann darunter erheblich leiden. from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1LXWxYF via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174 from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis… Continue reading Schönheitsspritze kann unschöne Folgen haben
Wird das Lungenkarzinom zur «chronischen Erkrankung»?
Präzisionsmedizin Diagnose. Behandlung. Resistenztestung. Therapiewechsel. Was aus der HIV-Therapie gut bekannt ist, wird auch für die Onkologie zum Paradigma. Am Lungenkrebs lässt sich das gut illustrieren, aber: Der Weg zum „chronischen Bronchialkarzinom“ ist noch weit. from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1nkPdjg via IFTTT
Variations in Case-Mix-Adjusted Duration of Mechanical Ventilation Among ICUs.
Objectives: To develop a model that predicts the duration of mechanical ventilation and then to use this model to compare observed versus expected duration of mechanical ventilation across ICUs. Design: Retrospective cohort analysis. Setting: Eighty-six eligible ICUs at 48 U.S. hospitals. Patients: ICU patients receiving mechanical ventilation on day 1 (n = 56,336) admitted from… Continue reading Variations in Case-Mix-Adjusted Duration of Mechanical Ventilation Among ICUs.
Impact of Proactive Nurse Participation in ICU Family Conferences: A Mixed-Method Study.
Objectives: To investigate family perceptions of having a nurse participating in family conferences and to assess the psychologic well being of the same families after ICU discharge. Design: Mixed-method design with a qualitative study embedded in a single-center randomized study. Setting: Twelve-bed medical-surgical ICU in a 460-bed tertiary hospital. Subjects: One family member for each… Continue reading Impact of Proactive Nurse Participation in ICU Family Conferences: A Mixed-Method Study.
Glucocorticoid Programming in Very Preterm Birth
Very preterm (i.e., Horm Res Paediatr from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/24Fo2ld via IFTTT
Growing Up After Critical Illness: Verbal, Visual-Spatial, and Working Memory Problems in Neonatal Extracorporeal Membrane Oxygenation Survivors.
Objectives: To assess neuropsychologic outcome in 17- and 18-year-old neonatal extracorporeal membrane oxygenation survivors. Design: A prospective longitudinal follow-up study. Setting: Follow-up program at the Erasmus MC-Sophia Children’s Hospital in Rotterdam, The Netherlands. Patients: Thirty adolescents 17 or 18 years old, treated between 1991 and 1997, underwent neuropsychologic assessment. Interventions: None. Measurements and Main Results:… Continue reading Growing Up After Critical Illness: Verbal, Visual-Spatial, and Working Memory Problems in Neonatal Extracorporeal Membr...περισσότερα »
Evaluation of Noninvasive Hemoglobin Monitoring in Surgical Critical Care Patients.
Objective: To assess the clinical utility of noninvasive hemoglobin monitoring based on pulse cooximetry in the ICU setting. Design and Setting: A total of 358 surgical patients from a large urban, academic hospital had the noninvasive hemoglobin monitoring pulse cooximeter placed at admission to the ICU. Core and stat laboratory hemoglobin measurements were taken at… Continue reading Evaluation of Noninvasive Hemoglobin Monitoring in Surgical Critical Care Patients.
Fibroblast Growth Factor 23 Concentrations Reflect Sex Differences in Mineral Metabolism and Growth in Early Infancy
Background: The role of fibroblast growth factor 23 (FGF23) in the regulation of mineral homeostasis in early life is inadequately understood. We aimed to explore the effects of vitamin D supplementation on serum FGF23 and to elucidate longitudinal changes in FGF23, in addition to studying its association with mineral metabolism in early infancy. Methods: Altogether… Continue reading Fibroblast Growth Factor 23 Concentrations Reflect Sex Differences in Mineral Metabolism and Growth in Early Infancy
Transfusion of 35-Day Stored RBCs in the Presence of Endotoxemia Does Not Result in Lung Injury in Humans.
Objective: Transfusion-related acute lung injury is the leading cause of transfusion-related mortality. Preclinical studies have shown that aged RBCs can induce transfusion-related acute lung injury in the presence of a «first hit» (e.g., sepsis). Clinical studies, however, show conflicting results on this matter. We tested whether maximally stored RBCs are able to induce lung injury… Continue reading Transfusion of 35-Day Stored RBCs in the Presence of Endotoxemia Does Not Result in Lung Injury in Humans.
The influence of bone mineral density and bisphosphonate therapy on the determinants of oral health and changes on dental panoramic radiographs in postmenopausal women
Abstract Objectives The aim of this study was to assess the determinants of oral health including the number of decayed, missing, and filled teeth (DMFT) and periodontal indices in postmenopausal women with osteoporosis, osteoporosis treated with bisphosphonate therapy, and control group and to examine the correlation between dental panoramic indices (Mental Index—MI, Mandibular Cortical Index—MCI) and bone mineral density in these three groups of patients. Materials and methods The presented non-interventional study involved 120 postmenopausal women: women with osteoporosis (O) ...περισσότερα »
Vascular Anatomy and Clinical Application of the Free Proximal Ulnar Artery Perforator Flaps
[image: image]Background: There is a dearth of detailed published work on the anatomy of ulnar artery perforators. The objective of this study was to fully document the vascular basis of the free proximal ulnar artery perforator flap and report its use in reconstruction of the hand. Methods: (1) The ulnar artery perforators were studied in 25 fresh cadavers and 10 cast preparations. Cadavers were injected with lead oxide for 3-dimensional reconstruction. The origin, course, and distribution of the ulnar artery perforators were comprehensively documented. (2) Between August 2011 and ... περισσότερα »
The Impact of Sleep Timing, Sleep Duration, and Sleep Quality on Depressive Symptoms and Suicidal Ideation amongst Japanese Freshmen: The EQUSITE Study
Aim. The aim of this study was to identify the impact of bedtime, wake time, sleep duration, sleep-onset latency, and sleep quality on depressive symptoms and suicidal ideation amongst Japanese freshmen. Methods. This cross-sectional data was derived from the baseline survey of the Enhancement of Q-University Students Intelligence (EQUSITE) study conducted from May to June, 2010. A total of 2,631 participants were recruited and completed the following self-reported questionnaires: the Pittsburgh Sleep Quality Index (PSQI), the Center for Epidemiologic Studies Depression Scale (CES... περισσότερα »
Label-free fluorescence detection of microRNA based on target induced adenosine2-coralyne-adenosine2 formation
[image: CrossMark.jpg] *Analyst*, 2016, Accepted Manuscript *DOI*: 10.1039/C6AN00001K, Communication Jun-Jie Li, Qiang Xi, Wen-Fang Du, Ruqin Yu, Jian-Hui Jiang This study develops a simple and label-free biosensor for sensitive and selective detection of microRNA (miRNA) based on the formation of adenosine2-coralyne-adenosine2 complex mediated by miRNA-specific polyadenosine extension. The content of this RSS Feed (c) The Royal Society of Chemistry from BioChemistry via xlomafota13 on Inoreader http://ift.tt/21JdqTs via IFTTT
Depleted interstitial cells of Cajal and fibrosis in the pylorus: Novel features of gastroparesis
Abstract Background Depletion and ultrastructural changes of interstitial cells of Cajal (ICC) in the gastric body and antrum have been observed in gastroparesis. This research was performed to investigate the ICC population in the muscularis propria and fibrosis of the muscular layer of the pylorus in gastroparesis. Methods Full thickness pyloric and antral biopsies were obtained from 17 gastroparetic and 6 non-gastroparetic controls. Biopsies were stained with C-Kit for ICC and Trichrome for collagen fibrosis. Interstitial cells of Cajal depletion in the antrum was defined as m... περισσότερα »
