Publication date: Available online 18 October 2017
Source:European Annals of Otorhinolaryngology, Head and Neck Diseases
Author(s): J. Lahmar, C. Célérier, E.N. Garabédian, V. Couloigner, N. Leboulanger, F. Denoyelle
ObjectivesTo study recent cases of esophageal injury due to button-battery ingestion in children presenting in pediatric ENT emergency departments of the Paris area of France (Île-de-France region), in order to propose appropriate preventive measures.Material and methodA retrospective descriptive single-center study included all children under 15 years of age, presenting in pediatric ENT emergency departments between January 2008 and April 2014 for button-battery ingestion with esophageal impaction requiring emergency removal.ResultsTwenty-two boys and 4 girls, with a median age of 25 months, were included. Twenty-five of the 26 batteries had diameters of 20mm or more. Median esophageal impaction time was 7 hours 30 minutes (range, 2 to 72 hours). The complications rate was 23%. Mean hospital stay cost was €38,751 (range, €5130–119,737). The origin of the battery was known in 23 of the 26 cases: remote control without screw-secured compartment (42.3%), open battery pack (15.4%), children's toy (15.3%), camera (7.7%), watch (1 case) and hearing aid without screw-secured compartment (1 case).ConclusionEsophageal lesions due to ingestion of button-batteries in children are almost always due to batteries larger than 20mm in diameter, mostly from devices with a poorly protected compartment, or batteries that are not individually packaged. These lesions cause serious complications in a quarter of cases and their management entails high health costs. Legislation requiring screw-secured compartments and individual blisters for batteries could have prevented 69.2% of the ingestions.
http://ift.tt/2yyDZks
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- Esophageal lesions following button-battery ingest...
- Gastric cancer: immunohistochemical classification...
- Macroglossia During Awake Craniotomy: A Near Miss.
- Correlation between computed tomography imaging an...
- Baseline asthma burden, comorbidities, and biomark...
- Evaluation of facial blood flow using three-dimens...
- Bleomycin electrosclerotherapy: new treatment to m...
- Prescription of antibiotics: does it alter the out...
- Surgical and social implications of extraction of ...
- Behavioral Animal Model of the Emotional Response ...
- Behavioral Animal Model of the Emotional Response ...
- Development and evaluation of novel biodegradable ...
- Development and evaluation of novel biodegradable ...
- Clinical implications of pathologic factors after ...
- Verathon launches portable handheld video laryngos...
- Treatment of keloid scars using light-, laser- and...
- Successful treatment of a recurrent granulation po...
- Priming Immunotherapy in Advanced Disease With Rad...
- Neoadjuvant Treatment Associated With Maintenance ...
- Recovery from Cogwheel Rigidity and Akinesia and I...
- Overt Lower Gastrointestinal Bleeding and Pseudotu...
- Book Review—Practical Hepatic Pathology: A Diagnos...
- Atypical Presentation of Sjögren-Larsson Syndrome
- In vitro bond strength of an epoxy resin-based roo...
- Fundamental Epidemiology Terminology and Measures:...
- Intraoperative Esmolol as an Adjunct for Periopera...
- Standardized Care Versus Precision Medicine: Do We...
- In Response: Subcellular Energetics and Metabolism...
- In Response: Standardized Care Versus Precision Me...
- Subcellular Energetics and Metabolism: A Cross-Spe...
- Patient Harm in Cataract Surgery: A Series of Adve...
- Patient Blood Management in Pediatric Cardiac Surg...
- Photoplethysmography and Heart Rate Variability fo...
- An Intraplantar Hypertonic Saline Assay in Mice fo...
- The Influence of Age on Sensitivity to Dexmedetomi...
- Pearls of Wisdom for High-Risk Laser Lead Extracti...
- A Survey Evaluating Burnout, Health Status, Depres...
- Preventing Adverse Events in Cataract Surgery: Rec...
- Incidence and Operative Factors Associated With Di...
- Thermal A-δ Nociceptors, Identified by Transcripto...
- Truncated μ-Opioid Receptors With 6 Transmembrane ...
- Higher Operating Table for Optimal Needle-Entry An...
- “Difficult Airway” Bibliometrics: Importance of Ca...
- Comparative Effectiveness Research in Health Services
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Τετάρτη 18 Οκτωβρίου 2017
Esophageal lesions following button-battery ingestion in children: Analysis of causes and proposals for preventive measures
Gastric cancer: immunohistochemical classification of molecular subtypes and their association with clinicopathological characteristics
Abstract
Gastric cancer is traditionally divided into intestinal and diffuse histological subtypes, but recent molecular analyses have led to novel classification proposals based on genomic alterations. While the intestinal- and diffuse-type tumours are distinguishable from each other at the molecular level, intestinal-type tumours have more diverse molecular profile. The technology required for comprehensive molecular analysis is expensive and not applicable for routine clinical diagnostics. In this study, we have used immunohistochemistry and in situ hybridisation in molecular classification of gastric adenocarcinomas with an emphasis on the intestinal subtype. A tissue microarray consisting of 244 gastric adenocarcinomas was constructed, and the tumours were divided into four subgroups based on the presence of Epstein-Barr virus, TP53 aberrations and microsatellite instability. The intestinal- and diffuse-type tumours were separately examined. The distribution of EGFR and HER2 gene amplifications was studied in the intestinal-type tumours. Epstein-Barr virus positive intestinal-type tumours were more common in male patients (p = 0.035) and most often found in the gastric corpus (p = 0.011). The majority of the intestinal-type tumours with TP53 aberrations were proximally located (p = 0.010). All tumours with microsatellite instability showed intestinal-type histology (p = 0.017) and were associated with increased overall survival both in the univariate (p = 0.040) and multivariate analysis (p = 0.015). In conclusion, this study shows that gastric adenocarcinomas can be classified into biologically and clinically different subgroups by using a simple method also applicable for clinical diagnostics.
http://ift.tt/2zjIRYe
Correlation between computed tomography imaging and histopathology in pleomorphic adenoma of parotid gland
The purpose of this study was to correlate the CT imaging features and histopathological findings of pleomorphic adenomas (PA), and also try to identify its clinical significance.
http://ift.tt/2ywEhGF
Baseline asthma burden, comorbidities, and biomarkers in omalizumab-treated patients in PROSPERO
Patients included in clinical trials do not necessarily reflect the real-world population.
http://ift.tt/2xPcMq5
Evaluation of facial blood flow using three-dimensional scanning
The Vectra X3 3-dimensional face scanner allows us to visualise the erythema of superficial layers of skin in addition to its regular scanning functions. The aim of our study was to find out whether changes we provoked in the circulation of the skin would be registered and displayed by the face scanner. We measured the circulation in the skin of the cheeks of 20 volunteers with a face scanner, a laser Doppler device, and a skin pigmentation analyser before and after the application of a nitric oxide cream.
http://ift.tt/2ywyDVd
Bleomycin electrosclerotherapy: new treatment to manage vascular malformations
Venous malformations are congenital anomalies of the vascular system. The injection of bleomycin (a cytotoxic, antitumour drug) into the lesion is a safe and effective treatment for low-flow (venous and lymphatic) malformations, but its use systemically has been associated with pulmonary fibrosis. Intralesional injection of bleomycin is considered to have a lower risk, but caution should be used when planning treatment, with particular regard to respiratory function. Electroporation is the temporary application of an electrical field across a tissue to increase (briefly) the permeability of the cell membrane in that tissue.
http://ift.tt/2x7bGGy
Prescription of antibiotics: does it alter the outcome for patients who have fractures of the angle of the mandible?
We retrospectively studied 708 consecutive patients at the Queen Elizabeth Hospital, Birmingham, to find out whether one of the four antibiotic protocols in use conferred any advantage (or disadvantage) on a patient who had a fractured angle of the mandible, and there was none. However, the time from initial injury until the time of the first dose of antibiotic was important. Clinically, if patients waited more than 72hours after the injury before the first dose of antibiotic was given, they had a three times higher rate of postoperative infection than patients who were given their first dose between 24 and 72hours after the injury.
http://ift.tt/2ywn5kH
Surgical and social implications of extraction of mandibular third molars as a separate procedure before bilateral sagittal split osteotomy
In some units, lower wisdom teeth are extracted in a separate procedure before bilateral sagittal split osteotomy (BSSO), whereas in others they are removed at the time of the osteotomy. We identified 57 patients who had BSSO at Salisbury Hospital between October 2013 and September 2015, 40 of whom had their wisdom teeth extracted at the same time. The remaining 17 did not have wisdom teeth. Patients who have these teeth extracted as a separate procedure require at least one day off work, which can result in a loss of earnings.
http://ift.tt/2x6giwz
Behavioral Animal Model of the Emotional Response to Tinnitus and Hearing Loss
Abstract
Increased prevalence of emotional distress is associated with tinnitus and hearing loss. The underlying mechanisms of the negative emotional response to tinnitus and hearing loss remain poorly understood, and it is challenging to disentangle the emotional consequences of hearing loss from those specific to tinnitus in listeners experiencing both. We addressed these questions in laboratory rats using three common rodent anxiety screening assays: elevated plus maze, open field test, and social interaction test. Open arm activity in the elevated plus maze decreased substantially after one trial in controls, indicating its limited utility for comparing pre- and post-treatment behavior. Open field exploration and social interaction behavior were consistent across multiple sessions in control animals. Individual sound-exposed and salicylate-treated rats showed a range of phenotypes in the open field, including reduced entries into the center in some subjects and reduced locomotion overall. In rats screened for tinnitus, less locomotion was associated with higher tinnitus scores. In salicylate-treated animals, locomotion was correlated with age. Sound-exposed and salicylate-treated rats also showed reduced social interaction. These results suggest that open field exploratory activity is a selective measure for identifying tinnitus distress in individual animals, whereas social interaction reflects the general effects of hearing loss. This animal model will facilitate future studies of the structural and functional changes in the brain pathways underlying emotional distress associated with hearing dysfunction, as well as development of novel interventions to ameliorate or prevent negative emotional responses.
http://ift.tt/2gtMqYd
Behavioral Animal Model of the Emotional Response to Tinnitus and Hearing Loss
Abstract
Increased prevalence of emotional distress is associated with tinnitus and hearing loss. The underlying mechanisms of the negative emotional response to tinnitus and hearing loss remain poorly understood, and it is challenging to disentangle the emotional consequences of hearing loss from those specific to tinnitus in listeners experiencing both. We addressed these questions in laboratory rats using three common rodent anxiety screening assays: elevated plus maze, open field test, and social interaction test. Open arm activity in the elevated plus maze decreased substantially after one trial in controls, indicating its limited utility for comparing pre- and post-treatment behavior. Open field exploration and social interaction behavior were consistent across multiple sessions in control animals. Individual sound-exposed and salicylate-treated rats showed a range of phenotypes in the open field, including reduced entries into the center in some subjects and reduced locomotion overall. In rats screened for tinnitus, less locomotion was associated with higher tinnitus scores. In salicylate-treated animals, locomotion was correlated with age. Sound-exposed and salicylate-treated rats also showed reduced social interaction. These results suggest that open field exploratory activity is a selective measure for identifying tinnitus distress in individual animals, whereas social interaction reflects the general effects of hearing loss. This animal model will facilitate future studies of the structural and functional changes in the brain pathways underlying emotional distress associated with hearing dysfunction, as well as development of novel interventions to ameliorate or prevent negative emotional responses.
http://ift.tt/2gtMqYd
Development and evaluation of novel biodegradable chitosan based metformin intrapocket dental film for the management of periodontitis and alveolar bone loss in a rat model
Publication date: January 2018
Source:Archives of Oral Biology, Volume 85
Author(s): Deepak Kumar Khajuria, Omprakash Nandikamba Patil, David Karasik, Rema Razdan
ObjectiveThe aim of this study was to develop a chitosan-metformin based intrapocket dental film (CMIDF) for applications in the treatment of periodontitis and alveolar bone loss in an rat model of periodontitis.DesignCMIDF inserts were fabricated by the solvent casting technique. The fabricated inserts were evaluated for physical characteristics such as folding endurance, surface pH, mucoadhesive strength, metformin content uniformity, and release. X-ray diffraction analysis indicates no crystallinity of metformin in presence of chitosan which confirmed successful entrapment of metformin into the CMIDF. Fourier-transform infrared spectroscopy revealed stability of CMIDF and compatibility between metformin and chitosan. Periodontitis was induced by a combination of Porphyromonas gingivalis- lipopolysaccharide injections in combinations with ligatures around the mandibular first molar. We divided rats into 5 groups (8 rats/group): healthy, untreated periodontitis; periodontitis plus CMIDF-A (1.99±0.09mg metformin; total mass-4.01±0.05mg), periodontitis plus CMIDF-B (2.07±0.06mg metformin; total mass-7.56±0.09mg), and periodontitis plus chitosan film (7.61±0.08mg). After four weeks, mandibles were extracted to evaluate alveolar bone loss by micro-computerized tomography and histological techniques.ResultsAlveolar bone was intact in the healthy group. Local administration of CMIDF resulted in significant improvements in the alveolar bone properties when compared to the untreated periodontitis group. The study reported here demonstrates that novel CMIDF showed good antibacterial activity and effectively reduced alveolar bone destruction in a rat model of experimental periodontitis.ConclusionsNovel CMIDF showed good antibacterial activity and improved alveolar bone properties in a rat model.
Graphical abstract
http://ift.tt/2ySmxJb
Development and evaluation of novel biodegradable chitosan based metformin intrapocket dental film for the management of periodontitis and alveolar bone loss in a rat model
Publication date: January 2018
Source:Archives of Oral Biology, Volume 85
Author(s): Deepak Kumar Khajuria, Omprakash Nandikamba Patil, David Karasik, Rema Razdan
ObjectiveThe aim of this study was to develop a chitosan-metformin based intrapocket dental film (CMIDF) for applications in the treatment of periodontitis and alveolar bone loss in an rat model of periodontitis.DesignCMIDF inserts were fabricated by the solvent casting technique. The fabricated inserts were evaluated for physical characteristics such as folding endurance, surface pH, mucoadhesive strength, metformin content uniformity, and release. X-ray diffraction analysis indicates no crystallinity of metformin in presence of chitosan which confirmed successful entrapment of metformin into the CMIDF. Fourier-transform infrared spectroscopy revealed stability of CMIDF and compatibility between metformin and chitosan. Periodontitis was induced by a combination of Porphyromonas gingivalis- lipopolysaccharide injections in combinations with ligatures around the mandibular first molar. We divided rats into 5 groups (8 rats/group): healthy, untreated periodontitis; periodontitis plus CMIDF-A (1.99±0.09mg metformin; total mass-4.01±0.05mg), periodontitis plus CMIDF-B (2.07±0.06mg metformin; total mass-7.56±0.09mg), and periodontitis plus chitosan film (7.61±0.08mg). After four weeks, mandibles were extracted to evaluate alveolar bone loss by micro-computerized tomography and histological techniques.ResultsAlveolar bone was intact in the healthy group. Local administration of CMIDF resulted in significant improvements in the alveolar bone properties when compared to the untreated periodontitis group. The study reported here demonstrates that novel CMIDF showed good antibacterial activity and effectively reduced alveolar bone destruction in a rat model of experimental periodontitis.ConclusionsNovel CMIDF showed good antibacterial activity and improved alveolar bone properties in a rat model.
Graphical abstract
http://ift.tt/2ySmxJb
Clinical implications of pathologic factors after thyroid lobectomy in patients with papillary thyroid carcinoma
Publication date: December 2017
Source:Oral Oncology, Volume 75
Author(s): Young Min Park, Doh Young Lee, Kyung Ho Oh, Jae-Gu Cho, Seung-Kuk Baek, Soon-Young Kwon, Kwang-Yoon Jung, Jeong-Soo Woo
ObjectiveWe evaluated the clinical and prognostic significance of pathologic factors by analyzing the treatment results of patients who underwent thyroid lobectomy.Materials and methodsWe retrospectively analyzed data from 734 patients diagnosed with papillary thyroid cancer who underwent thyroid lobectomy at Korea University Hospital from January 2004 to December 2016.ResultsA total of 734 patients were included in the study and their mean age was 44.5 years (range, 15–83). On univariate analysis, tumor size and recurrence-free survival were significantly related. The 10-year recurrence-free survival was 98.3% for tumors ≤1cm, 77.8% for >1cm and ≤2cm, and 66.7% for >2cm (p = 0.014). Recurrence-free survival was significantly different between patients with and without microscopic extrathyroidal extension (p=0.002). The 10-year recurrence-free survival rate was 99.2% for patients without extrathyroidal extension and 92.2% for patients with microscopic extrathyroidal extension. Multivariate analysis showed only microscopic extrathyroidal extension was significantly correlated with recurrence-free survival (p=0.029).ConclusionIn patients undergoing thyroid lobectomy for low-risk papillary thyroid cancer, microscopic extrathyroidal extension was an important prognostic factor associated with recurrence-free survival. However, in cases with microscopic extrathyroidal extension findings on postoperative pathologic examination, appropriate ultrasonographic follow-up of the contralateral thyroid lobe and cervical lymph node to facilitate early detection and prompt treatment of recurrence can control the disease without a deterioration of survival rate.
http://ift.tt/2grR0WL
Verathon launches portable handheld video laryngoscope system
By EMS1 Staff Verathon Inc. announced the launch of its GlideScope Go video laryngoscope system at EMS World Expo 2017. GlideScope Go features a scratch-resistant 3.5-inch color display with anti-glare coating and a wide field of view. It is compatible with GlideScope Spectrum single-use blades, for patients ranging from neonate to large adults. It is designed to provide clear airway views in a wide ...
http://ift.tt/2zxBnBD
Treatment of keloid scars using light-, laser- and energy-based devices: a contemporary review of the literature
Abstract
Keloid scars are common and have a predilection for young, ethnic skin often with a family history. Keloids can be painful and pruritic and cause significant emotional distress when particularly visible or prominent. In this article, we review the evidence underlying the use of laser- and energy-based devices for treatment of keloid scars, either as monotherapy or in conjunction with other therapies such as corticosteroids, surgery and silicone gel in the treatment of keloid scars.
http://ift.tt/2giXsLU
Successful treatment of a recurrent granulation polyp in the airways with high-dose-rate brachytherapy: a case report
Benign central airway tumors are very rare diseases. Their unspecific symptoms are responsible for late diagnosis. Endoscopic interventions with different techniques and tools are widely used for their treatme...
http://ift.tt/2xNZXw9
Priming Immunotherapy in Advanced Disease With Radiation
Interventions: Drug: Immune checkpoint inhibitor; Radiation: Radiation Therapy
Sponsor: John L. Villano, MD, PhD
Not yet recruiting
http://ift.tt/2gsbYos
Neoadjuvant Treatment Associated With Maintenance Therapy by Anti-PD1 Immunotherapy in Patients With Resectable Head and Neck Mucosal Melanoma
Interventions: Drug: Pembrolizumab; Procedure: Surgery; Radiation: IMRT
Sponsor: Gustave Roussy, Cancer Campus, Grand Paris
Not yet recruiting
http://ift.tt/2yyRNvt
Recovery from Cogwheel Rigidity and Akinesia and Improvement in Vibration Sense and Olfactory Perception following Removal of an Epoxy-Oleic Acid DNA Adduct
The epoxy fatty acid cis-12,13-epoxy-oleic acid, which acts as a DNA adduct, may be generated during long-term storage of many seed oils, including those used in cooking, with frying oils and fried foods being a major source in the modern human diet. Removal of this epoxy fatty acid from the locus of the N-formyl peptide receptors was associated with recovery from cogwheel rigidity and akinesia as well as with improvement in vibration sense and olfactory perception.
http://ift.tt/2ySBR8D
Overt Lower Gastrointestinal Bleeding and Pseudotumor: A Rare Presentation of Cytomegalovirus Infection
Cytomegalovirus (CMV) is a ubiquitous organism which can infect multiple organs of the body. In an immunocompromised patient, it can have a myriad of gastrointestinal manifestations. We report a case of recurrent hematochezia and concomitant pseudotumor in an AIDS (acquired immunodeficiency syndrome) patient attributable to CMV infection. A 62-year-old man with a history of AIDS, noncompliant with highly active antiretroviral therapy (HAART), presented with bright red blood per rectum. Index colonoscopy showed presence of multiple ulcers, colonic stenosis, and mass-like appearing lesion. Biopsy confirmed CMV infection and ruled out malignancy. Cessation of dual antiplatelet therapy and compliance with HAART lead to clinical cessation of bleeding and endoscopic healing of ulcers with complete resolution of colon mass on follow-up colonoscopy.
http://ift.tt/2hNcn1q
Atypical Presentation of Sjögren-Larsson Syndrome
Sjögren-Larsson syndrome is a rare neurocutaneous disorder characterized by ichthyosis, spastic diplegia or tetraplegia, and intellectual disability. Herein, we describe a case of a Greek patient with ichthyosis and spasticity of the legs but with normal intelligence (IQ 95). This syndrome should be suspected when a child presents with ichthyosis and spastic diplegia or tetraplegia, even if intelligence is normal.
http://ift.tt/2zhTtqy
In vitro bond strength of an epoxy resin-based root canal sealer to root dentin irradiated with high-power lasers and adhesive interface analyses
Abstract
The aim of this study was to evaluate in vitro the influence of high-power lasers (Nd:YAG and diode 980 nm) associated with mineral coal as fotopotencializer on bond strength of an epoxy resin-based root canal sealer to root dentin, using the pushout test, and on the dentin/filling material interface, using confocal laser microscopy. For this purposes, 50 canines were instrumented with Mtwo rotary system up to #50.04 instrument and randomly assigned to five groups (n = 10): group I—control EDTAC; group II—EDTAC and Nd:YAG laser; group III—EDTAC and diode laser 980 nm; group IV—EDTAC, Nd:YAG laser and mineral coal 5 g/100 mL; and group V—EDTAC, diode laser 980 nm and mineral coal 5 g/100 mL. All data were analyzed by ANOVA (at 5% significance level) following the Kruskal-Wallis, Dunn and Tukey tests. The group I increased more bond strength of the sealer to root dentin that treated with only EDTAC 17% (17.21 ± 21.75 MPa), similar to the group II (12.21 ± 18.20 MPa) and group IV (14.92 ± 28.06 MPa), both treated with Nd:YAG laser, with the exception of group IV, which was added to mineral coal. The group V (8.75 ± 13.42 MPa) had similar results to the groups II and IV, but the same similarity were found when compared with group III (7.11 + 11.28 MPa), with lower results. Regarding the root thirds, the apical third (23.27 ± 29.21 MPa) presented a statistically higher value on bond strength than the cervical third (5.92 ± 5.33 MPa) and middle third (6.93 ± 7, 11 MPa) (p > 0.05). Group II (86.27 μm) showed the highest tags penetration values, with a statistically difference to the group III (51.57 μm), IV (36.77 μm) and V (32.37 μm) (p < 0.05). Group I (71.63 μm) was statistically similar to groups II and III (p > 0.05). Group IV had the lowest values and was statistically similarity to groups III and V (p > 0.05). It was concluded that the treatment with Nd:YAG laser provides better results than the diode 980 nm laser, except when was added mineral coal. The control and diode 980 nm laser groups presented less adhesive failures and more mists failures than the other groups. Both lasers did not interfere negatively compared to the control group.
http://ift.tt/2kXwBKJ
Fundamental Epidemiology Terminology and Measures: It Really Is All in the Name
http://ift.tt/2yr7JAk
Intraoperative Esmolol as an Adjunct for Perioperative Opioid and Postoperative Pain Reduction: A Systematic Review, Meta-analysis, and Meta-regression
http://ift.tt/2giyBYM
Patient Harm in Cataract Surgery: A Series of Adverse Events in Massachusetts
http://ift.tt/2yqKPJG
Patient Blood Management in Pediatric Cardiac Surgery: A Review
http://ift.tt/2giypsw
Photoplethysmography and Heart Rate Variability for the Diagnosis of Preeclampsia
http://ift.tt/2yrYfEW
An Intraplantar Hypertonic Saline Assay in Mice for Rapid Screening of Analgesics
http://ift.tt/2gis9Ru
The Influence of Age on Sensitivity to Dexmedetomidine Sedation During Spinal Anesthesia in Lower Limb Orthopedic Surgery
http://ift.tt/2ypsE77
Pearls of Wisdom for High-Risk Laser Lead Extractions: A Focused Review
http://ift.tt/2gjqECI
A Survey Evaluating Burnout, Health Status, Depression, Reported Alcohol and Substance Use, and Social Support of Anesthesiologists
http://ift.tt/2yqKO8A
Preventing Adverse Events in Cataract Surgery: Recommendations From a Massachusetts Expert Panel
http://ift.tt/2giMfex
Incidence and Operative Factors Associated With Discretional Postoperative Mechanical Ventilation After General Surgery
http://ift.tt/2yqv6tS
Thermal A-δ Nociceptors, Identified by Transcriptomics, Express Higher Levels of Anesthesia-Sensitive Receptors Than Thermal C-Fibers and Are More Suppressible by Low-Dose Isoflurane
http://ift.tt/2ghGfT5
Truncated μ-Opioid Receptors With 6 Transmembrane Domains Are Essential for Opioid Analgesia
http://ift.tt/2ypKcQh
Higher Operating Table for Optimal Needle-Entry Angle and Less Discomfort During Spinal Anesthesia
http://ift.tt/2gi969N