Αρχειοθήκη ιστολογίου

Αλέξανδρος Γ. Σφακιανάκης
ΩτοΡινοΛαρυγγολόγος
Αναπαύσεως 5
Άγιος Νικόλαος Κρήτη 72100
2841026182
6032607174

Τετάρτη 25 Μαΐου 2016

OtoRhinoLaryngology & Medicine,New Articles,May 25th,2016


[Stretch sphincter of the esophagus : Paradoxical sphincter with angiomyoelastic architecture].

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 1 λεπτό
[image: http:--production.springer.de-OnlineReso] Related Articles *[Stretch sphincter of the esophagus : Paradoxical sphincter with angiomyoelastic architecture].* Chirurg. 2015 Aug;86(8):752-60 Authors: Stelzner F Abstract The investigations described in this article clearly show that the lower esophageal sphincter (LES) represents a variation of circular muscular occlusive mechanisms found elsewhere in the gastrointestinal tract. The LES is a double layer stretch sphincter that operates in an apparently paradoxical manner: it closes when under stretch but opens when the muscle... περισσότερα »

Randomized study comparing inflammatory response after tonsillectomy versus tonsillotomy.

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 1 λεπτό
*Randomized study comparing inflammatory response after tonsillectomy versus tonsillotomy.* Eur Arch Otorhinolaryngol. 2016 May 23; Authors: Kordeluk S, Goldbart A, Novack L, Kaplan DM, El-Saied S, Alwalidi M, Shapira-Parra A, Segal N, Slovik Y, Max P, Joshua BZ Abstract To determine if there was a difference in the inflammatory reaction after tonsil surgery with "traditional" techniques (tonsillectomy and adenoidectomy or TA) compared to partial intracapsular tonsillectomy and adenoidectomy (PITA). DESIGN: Randomized, double-blind study. SETTING: tertiary care academic hospital. ...περισσότερα »

Impact of invasive ventilation on survival when non-invasive ventilation is ineffective in patients with Duchenne muscular dystrophy: A prospective cohort.

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 1 λεπτό
*Impact of invasive ventilation on survival when non-invasive ventilation is ineffective in patients with Duchenne muscular dystrophy: A prospective cohort.* Respir Med. 2016 Jun;115:26-32 Authors: Boussaïd G, Lofaso F, Santos DB, Vaugier I, Pottier S, Prigent H, Bahrami S, Orlikowski D Abstract BACKGROUND: Many patients with DMD undergo tracheostomy. Tracheostomy is associated with certain complications, however its effect on prognosis is not known. METHODS: The relationship between type of mechanical ventilation and survival at 12 years was evaluated in a prospective cohort of ...περισσότερα »

CLINICAL PROBLEM-SOLVING. Eye of the Beholder.

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 1 λεπτό
Related Articles *CLINICAL PROBLEM-SOLVING. Eye of the Beholder.* N Engl J Med. 2016 May 5;374(18):1774-9 Authors: MacFarlane L, Osman N, Ritter S, Miller AL, Loscalzo J PMID: 27144853 [PubMed - indexed for MEDLINE] from Swallowing and Swallowing Disorders (Dysphagia) via a.lsfakia on Inoreader http://ift.tt/247fYGQ via IFTTT

[Paradoxical sphincters in the abdomen].

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 1 λεπτό
[image: http:--production.springer.de-OnlineReso] Related Articles *[Paradoxical sphincters in the abdomen].* Chirurg. 2015 Aug;86(8):761-70 Authors: Stelzner F Abstract Nitric oxide molecules serve as neurotransmitters to relax smooth muscle tension in many parts of the body. In humans and other mammals they play an important role for correct smooth muscle function in unusual locations. We previously described this mechanism (Stelzner, Chirurg. doi:10.1007/s00104-014-2777-z, 2014) using the occlusive mechanism of the upper and lower esophageal sphincters as an example. Cells pro... περισσότερα »

Echo time-dependent quantitative susceptibility mapping contains information on tissue properties

Purpose Magnetic susceptibility is a physical property of matter that varies depending on chemical composition and abundance of different molecular species. Interest is growing in mapping of magnetic susceptibility in the human brain using magnetic resonance imaging techniques, but the influences affecting the mapped values are not fully understood. Methods We performed quantitative susceptibility mapping […]

The imidazoline compound RX871024 promotes insulinoma cell death independent of AMP-activated protein kinase inhibition

Summary We have previously shown that the insulinotropic imidazoline compound RX871024 induces death of insulinoma MIN6 cells, an effect involving stimulation of c-Jun N-terminal kinase (JNK) and caspase 3. It has also been reported that AMP-activated protein kinase (AMPK) activates JNK and induces β-cell death. Here we show that RX871024, but not another insulinotropic imidazoline […]

Pharmacokinetics and excretion of 14 C-omacetaxine in patients with advanced solid tumors

Summary Background Omacetaxine mepesuccinate is indicated in adults with chronic myeloid leukemia resistant and/or intolerant to ≥ 2 tyrosine kinase inhibitor treatments. This phase I study assessed the disposition, elimination, and safety of 14C-omacetaxine in patients with solid tumors. Methods The study comprised a 7-days pharmacokinetic assessment followed by a treatment period of ≤ six 28-days cycles. A single […]

The Effect of Menstrual Cycle on Singing Voice: A Systematic Review

Research has reported the difference in a woman’s voice across the different stages of the menstrual cycle. A review of the studies in singers on the influence of menstruation on the singing voice will enable a better understanding of these changes. (Source: Journal of Voice) from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1TE1NGp via IFTTT Medicine […]

A RCT to Compare the Pneupac VR1 Portable Ventilator and Manual Ventilation Via a Mapleson C- Circuit During the Intra-hospital Transfers of Intubated Patients

Condition: Cancer Intervention: Device: Pneupac VR1 Sponsors: Brighton and Sussex University Hospitals NHS Trust; St Thomas’ Hospital, London Not yet recruiting – verified May 2016 from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1YZ3QGo via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174

Hyperfractionated Intensity-modulated Radiotherapy (IMRT) Versus Conventional Fraction IMRT for Patients With Loco-regionally Recurrent Nasopharyngeal Carcinoma.

Conditions: Nasopharyngeal Neoplasms; Mortality; Quality of Life; Complications Interventions: Radiation: Hyperfractionated IMRT; Radiation: Conventional Fraction IMRT Sponsor: Sun Yat-sen University Recruiting – verified May 2016 from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1WOktqm via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174

Eine inakzeptable Studie

from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1s9CEdG via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174

AD-Risikodiagnostik baut Ängste vor Alzheimer ab

from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1ON0wsh via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174

Les particularités du lipofilling chez l’enfant

Publication date: Available online 24 May 2016 Source:Annales de Chirurgie Plastique Esthétique Author(s): C. Baptista, B. Bertrand, C. Philandrianos, N. Degardin, D. Casanova Le lipofilling ou transfert de tissu graisseux est défini comme une technique de comblement des tissus mous par injection de graisse autologue. Le principe de base du lipofilling repose sur un prélèvement […]

[Stretch sphincter of the esophagus : Paradoxical sphincter with angiomyoelastic architecture].

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngolgy NewsΠριν από 14 δευτερόλεπτα
[image: http:--production.springer.de-OnlineReso] Related Articles *[Stretch sphincter of the esophagus : Paradoxical sphincter with angiomyoelastic architecture].* Chirurg. 2015 Aug;86(8):752-60 Authors: Stelzner F Abstract The investigations described in this article clearly show that the lower esophageal sphincter (LES) represents a variation of circular muscular occlusive mechanisms found elsewhere in the gastrointestinal tract. The LES is a double layer stretch sphincter that operates in an apparently paradoxical manner: it closes when under stretch but opens when the muscle... περισσότερα »

Persistence of respiratory and inflammatory responses after dermal sensitization to persulfate salts in a mouse model of non-atopic asthma

Exposure to ammonium persulfate (AP) has been reported to be the main cause of occupational asthma in hairdressers. The aim of this study is to assess how long the asthmatic response to AP can be induced after… from Allergy via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1Tygu0Y via IFTTT

Primary immunodeficiencies associated with eosinophilia

Eosinophilia is not an uncommon clinical finding. However, diagnosis of its cause can be a dilemma once common culprits, namely infection, allergy and reactive causes are excluded. Primary immunodeficiency dis… from Allergy via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1TygeyR via IFTTT

Orbitofacial Metastatic Basal Cell Carcinoma

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 26 δευτερόλεπτα
Report of 10 Cases.: Purpose: To explore the clinical features, management, and prognosis of metastatic basal cell carcinoma originating in the orbitofacial region. Methods: Ten cases of orbitofacial metastatic basal cell carcinoma were identified by searching databases at 2 institutions from 1995 to 2015. A retrospective chart review was performed. Main outcome measures included patient demographics, lesion size, location of metastases, histologic subtype, recurrence rate, time between primary tumor diagnosis and metastasis, perineural invasion, treatment modalities, and survival ...περισσότερα »

The oral microbiome

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 26 δευτερόλεπτα
A practical guide to the oral microbiome and its relation to health and disease by K Krishnan, T Chen, BJ Paster via Oral Diseases Abstract The oral microbiome is incredibly complex with the average adult harboring about 50 to 100 billion bacteria in the oral cavity, which represent about 200 predominant bacterial species. Collectively, there are approximately 700 predominant taxa of which less than 1/3 still have not yet been grown *in vitro*. Compared to other body sites, the oral microbiome is unique and readily accessible. There is extensive literature available describing the or... περισσότερα »

Disordered Arrangements of Basal Cells as a Prognostic Factor for Oral Epithelial Dysplasia

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 26 δευτερόλεπτα
: A Morphometrical Study of 96 Cases via Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology *Source:*Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology Author(s): Takeshi Okamura, Toshiyuki Izumo, Hisao Yagishita, Taisuke Mori, Kei Sakamoto, Kiyoshi Harada ObjectiveThe aim of this study was to objectively assess the predictive value of the atypical appearance of the basal layer of oral epithelial dysplasia (OED) for development into invasive carcinoma.Study DesignNinety-six OED cases were examined. These cases were divided into two groups: 38 cases that develope... περισσότερα »

Follow-up of oral cancer patients; three uneventful years

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 26 δευτερόλεπτα
may be enough via Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology *Source:*Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology Author(s): Sharon.J. Taslim, C.René Leemans, Isaäc van der Waal, K.H. Karagozoglu ObjectivesTo explore the possibility of shortening the length of follow-up from five to three years in patients who have undergone curative treatment of an oral squamous cell carcinoma.MethodsThe medical records of 225 patients who had undergone initial curative treatment at the VU University Medical Center in Amsterdam, the Netherlands, between 2004 and... περισσότερα »

Continuous Neuropathic Pain Secondary to Endoscopic Procedures

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 26 δευτερόλεπτα
: Report of Two Cases and Review of the Literature via Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology *Source:*Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology Author(s): Mythili Kalladka, Cibele Nasri Heir, Eli Eliav, Sowmya Ananthan, Archana Viswanath, Gary Heir Neuropathic pain encompasses a spectrum of conditions that can arise from a lesion or dysfunction of the central or the peripheral nervous system, and it may develop at variable intervals after nerve injury or inflammation. Nerve injuries arising from surgical procedures commonly occurs secondary ...περισσότερα »

CASP8, MLH1, and RARB tumor suppressor genes were altered by copy number losses during the PA tumorigenesis into CXPA. Lastly, RASSF1 inactivation by methylation was also detected in both tumors.

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 26 δευτερόλεπτα
Evaluation of a Subset of Tumor Suppressor Gene for copy number and Epigenitic Changes in Pleomorphic Adenoma and Carcinoma ex-Pleomorphic Adenoma Carcinogenesis via Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology *Source:*Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology Author(s): Fernanda Viviane Mariano, Erika Said Egal, Dimitrius Pramio, Felipe Fidalgo, Érica Sara, Ana Flávia Costa, Rogério de Oliveira Gondak, Ricardo Della Coletta, Oslei Paes de Almeida, Luiz Paulo Kowalski, Ana Cristina Victorino Krepischi, Albina Altemani IntroductionThe progression... περισσότερα »

Pediatric Unilateral Facial Swelling

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 26 δευτερόλεπτα
ClinicoPathologic Conference: via Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology [image: a: Significant left facial swelling extending from the infraorbital region to ...] [image: Transverse axial cone beam of the left maxillary mass illustrating obliteration ...] [image: A biopsy showing diffuse atypical lymphoid proliferation consisting of ...] [image: Complete resolution of the facial swelling and intra-oral mass post- ...] *Source:*Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology Author(s): Awatef Draz, Wael Elias, Azza El-Sissi, Min-Ling Liu

Flurbiprofen, Diclofenac Sodium and Tenoxicam On Postoperative Pain, Swelling and Trismus

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 26 δευτερόλεπτα
: A Randomized Double-Blind Study via Oral and Maxillofacial Surgery *Source:*Journal of Oral and Maxillofacial Surgery Author(s): Volkan Kaplan, Cennet Neslihan Eroğlu PurposeThe aim of this study is to compare the effects of daily single dose use of flurbiprofen, diclofenac sodium and tenoxicam on pain, swelling and trismus that occur following surgical extraction of impacted wisdom teeth under local anesthesia.MethodsThe study included three groups with 30 individuals in each group. Individuals volunteering to participate in this double-blind randomized study (n=90) were selected fr...περισσότερα »

Dentigerous cyst : Cardiac tamponade due to Actinomyces odontolyticus

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 26 δευτερόλεπτα
Cardiac tamponade due to Actinomyces odontolyticus originating from a dentigerous cyst via Oral and Maxillofacial Surgery *Source:*Journal of Oral and Maxillofacial Surgery Author(s): E. Broly, J. Risse, F. Maschino, D. Wahl We report a rare case of pericardial effusion due to Actinomyces odontolyticus in a 52 year-old female patient, originating from a dentigerous cyst, which developed on the distal aspect of a lower left third molar. The cyst had remained asymptomatic for a long period of time, with no specific functional complications.This is the first case report on a patient suff... περισσότερα »

Ossifying fibroma (OF)

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 26 δευτερόλεπτα
analysis of treatment methods and recurrence patterns via Oral and Maxillofacial Surgery *Source:*Journal of Oral and Maxillofacial Surgery Author(s): Fadi Titinchi, Jean Morkel PurposeOssifying fibroma (OF) is one of the most frequent of the three fibro-osseous lesions of the jaws and has inconstant recurrence rate while a definitive surgical protocol is lacking in the literature. The aim of this study was to determine the clinical and radiological features of OF at a tertiary hospital in South Africa as well as to assess its management and recurrence patterns and develop a surgical ... περισσότερα »

Maxillary sinus floor elevation

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 26 δευτερόλεπτα
A comprehensive clinical review of maxillary sinus floor elevation: anatomy, techniques, biomaterials and complications: Several systematic reviews have shown that maxillary sinus augmentation is a predictable and effective procedure for augmentation of an atrophic posterior maxilla. However, we know of no reviews that have covered all the clinical aspects. We searched the PubMed, EMBASE, Cinhal, and Cochrane databases up to January 2015 to select relevant studies that cover the different objectives of this review, including the anatomy of the maxillary sinus, surgical techniques, b... περισσότερα »

Carotid-Cavernous Fistula as a Complication of Panfacial Fracture

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 26 δευτερόλεπτα
Case Report 11 Years after the Surgery: Cranial Maxillofac Trauma Reconstruction DOI: 10.1055/s-0036-1582458 The carotid-cavernous fistula (CCF) is a rare complication in patients victimized by craniofacial trauma. It involves multidisciplinary medical action. Owing to its potential complications, it is essential that maxillofacial surgery and neurosurgery specialists diagnose this condition so that appropriate treatment can be performed. The authors present a report of a case 11 years after the surgery.

OSCC : The tropism of lymphatic dissemination

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 26 δευτερόλεπτα
Exosomes from oral squamous carcinoma cell lines, SQUU-A and SQUU-B, define the tropism of lymphatic dissemination via ScienceDirect Publication: Journal of Oral Biosciences *Source:*Journal of Oral Biosciences Author(s): Masahiko Morioka, Tomoyo Kawakubo-Yasukochi, Yoshikazu Hayashi, Mai Hazekawa, Takuya Nishinakagawa, Kazuhiko Ono, Shintaro Kawano, Seiji Nakamura, Manabu Nakashima Oral squamous cell carcinoma (OSCC) is often associated with lymphatic rather than hematogenous metastasis; however, a determinant factor for this process has not been elucidated. This study examined the ef... περισσότερα »

Cranial and facial symmetry in hemicoronal single suture synostosis

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 26 δευτερόλεπτα
Photometric evaluation of cranial and facial symmetry in hemicoronal single suture synostosis treated with surgical fronto-orbital remodeling via ScienceDirect Publication: Journal of Cranio-Maxillofacial Surgery *Source:*Journal of Cranio-Maxillofacial Surgery Author(s): Fabio Mazzoleni, Maria Costanza Meazzini, Giorgio Novelli, Valentina Basile, Carlo Giussani, Alberto Bozzetti ObjectiveEvaluation of frontal vault symmetry and progressive facial symmetrization in a cohort of patients with hemicoronal single suture synostosis treated with a standardized cranioplasty and rigid fixation... περισσότερα »

Hydraulic Schneiderian membrane elevation and simultaneously bone graft augmentation

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 26 δευτερόλεπτα
A novel implant system dedicate to hydraulic Schneiderian membrane elevation and simultaneously bone graft augmentation: an up-to 4-year retrospective clinical study via ScienceDirect Publication: Journal of Cranio-Maxillofacial Surgery *Source:*Journal of Cranio-Maxillofacial Surgery Author(s): Marco Tallarico, Haddar Better, Giacomo De Riu, Silvio Mario Meloni Purposeto evaluate clinical and radiographic performance of a novel implant system that allows for hydraulic Schneiderian membrane elevation and simultaneously bone graft augmentation.Materials and MethodsSixty-two consecutive... περισσότερα »

Lengthening temporalis myoplasty versus free muscle transfer with the gracilis flap for long-standing facial paralysis

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 26 δευτερόλεπτα
: A systematic review of outcomes via ScienceDirect Publication: Journal of Cranio-Maxillofacial Surgery Publication date: Available online 25 May 2016 *Source:*Journal of Cranio-Maxillofacial Surgery Author(s): Rafael Bos, Srivinas Gosla Reddy, Maurice Y. Mommaerts

The American Sleep and Breathing Academy (ASBA)

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 26 δευτερόλεπτα
Future Reimbursement In Dental Sleep Medicine To Be Based On Diplomacy And Patient Outcomes: The American Sleep and Breathing Academy (ASBA) is an organization dedicated to enriching our members’ knowledge and skill in the treatment of sleep disordered breathing. Our goal is to provide current evidence based information to our members and enable them to provide optimal treatment for their patients. The ASBA offers Certification to its members as a confirmation of their knowledge, skill and experience. While there are multiple levels of Certification within our organization, the pr...περισσότερα »

Suction Cup Induced Palatal Fistula: Surgical Closure by Palatal Rotational Flap.

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 26 δευτερόλεπτα
Suction Cup Induced Palatal Fistula: Surgical Closure by Palatal Rotational Flap Ann Med Health Sci Res. 2016;6(2):129-32 Authors: Vaaka P, Donga SK, Ganapathi AK, Devi PB, Kaluvakolanu S, Mohammad Z Abstract Construction of complete denture with adequate retention is a complex procedure. Use of suction cup in a maxillary denture is one of the techniques to improve retention. Palatal Suction cup, which provides high retention by inducing negative pressure on the mucosal surface, is not being recommended because of its pathological effect on the palatal tissues leading to palatal ...περισσότερα »

Proteeae isolates displaying multidrug-resistance (MDR) are the second most common causes of hospital-associated infections

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 26 δευτερόλεπτα
Characterization of Integrons and qnr Genes in Proteeae from a Teaching Hospital in China: *Background:* Proteeae isolates displaying multidrug-resistance (MDR) are the second most common causes of hospital-associated infections. The aim of this study was to screen class 1-3 integrons and plasmid-mediated quinolone resistance (PMQR) genes in Proteeae isolates from the First Affiliated Hospital of the Wenzhou Medical University. *Materials and Methods:* 176 Proteeae isolates were collected from clinical specimens of inpatients between January 2011 and December 2013. Susceptibility te...περισσότερα »

Intravenous vitamin C on post-operative pain in uvulopalatopharyngoplasty with tonsillectomy

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 26 δευτερόλεπτα
Effect of Abstract Background Postoperative pain is a common problem in hospitals. Adults undergoing uvulopalatopharyngoplasty (UPPP) with tonsillectomy experience an unacceptable level of intense postoperative pain, especially during the first 24 hours after surgery. The present study investigated the analgesic effects of vitamin C in patients undergoing UPPP and tonsillectomy. Method This study was done on forty patients that were evaluated in a randomized double blinded clinical trial. Patients included in the study were within the age range of 25-50 years with BMI<35, physical st... περισσότερα »

Oligometastases in AJCC stage IVc nasopharyngeal carcinoma

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 26 δευτερόλεπτα
A subset with better overall survival: Abstract Background The purpose of this study was to analyze the patterns of metastasis and therapeutic approaches in American Joint Committee on Cancer (AJCC) stage IVc nasopharyngeal carcinoma (NPC). Methods A retrospective analysis of 263 patients with stage IVc NPC revealed the incidence of bone, liver, and lung metastases was 67.7%, 32.3%, and 16.0%, respectively. All patients received chemotherapy; 160 patients received radiotherapy (RT) to the primary tumor. Results The factors associated with poor overall survival (OS) were Karnofsk... περισσότερα »

Metastases to nasal cavity and paranasal sinuses

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 26 δευτερόλεπτα
Metastases to nasal cavity and paranasal sinuses: Abstract The sinonasal cavities are rare locations for metastases. Metastases to these locations are usually solitary and produce similar symptoms to those of a primary sinonasal tumor. Nasal obstruction and epistaxis are the most frequent symptoms. The maxillary sinus is most frequently involved. The most common primary tumor sites to spread to this region originate in the kidney, breast, thyroid, and prostate, although any malignancy could potentially lead to a metastasis to the paranasal sinuses. The patient's prognosis is us... περισσότερα »

Tumoren der ableitenden Tränenwege

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 26 δευτερόλεπτα
Tumoren der ableitenden Tränenwege: Zusammenfassung HintergrundAufgrund der geringen Prävalenz von Tumoren des Tränenwegssystems besteht die Gefahr, diese im klinischen Alltag erst spät zu diagnostizieren und zu behandeln. Eine Neoplasie in diesem Bereich kann jedoch für den Patienten u. U. lebensbedrohlich sein. FragestellungDieser Artikel gibt einen Überblick über Symptome, Inzidenz sowie den Umgang mit Tumoren verschiedener Entitäten im Bereich des ableitenden Tränenwegssystems und deren Prognose. MethodenDer Beitrag bietet eine Literaturübersicht aus Pubmed und eigene k... περισσότερα »

The sphenoid sinus, foramen rotundum and vidian canal

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 26 δευτερόλεπτα
: a radiological study of anatomical relationships via ScienceDirect Publication: Brazilian Journal of Otorhinolaryngology Publication date: Available online 24 May 2016 *Source:*Brazilian Journal of Otorhinolaryngology Author(s): Alireza Mohebbi, Shahin Rajaeih, Mahdi Safdarian, Parisa Omidian IntroductionThe sphenoid sinus is an important structure in ventral skull base surgeries that is surrounded by several vital anatomical structures including the internal carotid arteries, optic nerve and cranial nerves inside the cavernous sinus. In addition, the foramen rotundum is a small canal... περισσότερα »

Personal music systems and hearing

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 26 δευτερόλεπτα
Main ArticlePersonal music systems and hearingU A Kumara1 c1 and S R Deepashreea1 a1 Department of Audiology, All India Institute of Speech and Hearing, Manasagangothri, Mysore, India Abstract Objectives: To measure the output sound pressure levels of personal music systems and evaluate their effect on hearing. Methods: Output sound pressure levels at preferred volume settings and listening environment were measured using a manikin. Effects of personal music system use on hearing were evaluated using pure tone audiometry (in conventional and extended high frequency ranges), transient ...περισσότερα »

Chicago Fire Department ready for Ebola patient transport

Αλέξανδρος ΣφακιανάκηςστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 30 δευτερόλεπτα
A newly equipped ambulance uses a battery-powered pressurized plastic tent and air filtration system from EMS via xlomafota13 on Inoreader http://ift.tt/1WSXyuS

Grade school student made an honorary paramedic

Αλέξανδρος ΣφακιανάκηςστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 30 δευτερόλεπτα
MIDHURST, Ontario — An elementary school student spent a day away from school as an honorary paramedic to learn about emergency services. Olivia Gater, a fifth grade student, submitted the winning essay for a National Paramedic Services Week contest to the County of Simcoe Paramedic Services. She received a certificate, first aid bag, and stethoscope before spending the day with a paramedic crew learning about the job. Gater read her winning essay to the Simcoe County councilors at the start of National Paramedic Services Week, reported Barrie Today. "Paramedics are essential to t... περισσότερα »

Quickstats: Age-adjusted suicide rates for females and males, by method - National Vital Statistics System, United States, 2000 and 2014

Αλέξανδρος ΣφακιανάκηςστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 30 δευτερόλεπτα
Morbidity and Mortality Weekly Report from Emergency Medicine via xlomafota13 on Inoreader http://ift.tt/22oQ5mB

Acute heart failure with and without acute coronary syndrome: Clinical correlates and prognostic impact (From the HEARTS registry)

Αλέξανδρος ΣφακιανάκηςστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 30 δευτερόλεπτα
BMC Cardiovascular Disorders from Emergency Medicine via xlomafota13 on Inoreader http://ift.tt/1TxVp6Q

Learning curves for ultrasound assessment of lumbar puncture insertion sites: When is competency established?

Αλέξανδρος ΣφακιανάκηςστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 30 δευτερόλεπτα
The Journal of Emergency Medicine from Emergency Medicine via xlomafota13 on Inoreader http://ift.tt/22oPRfl

Development of a new Emergency Medicine Spinal Immobilization Protocol for trauma patients and a test of applicability by German emergency care providers

Αλέξανδρος ΣφακιανάκηςστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 30 δευτερόλεπτα
Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine from Emergency Medicine via xlomafota13 on Inoreader http://ift.tt/1TxVoji

Remote preconditioning protects early renal functions in low risk cardiac surgery patients

Αλέξανδρος ΣφακιανάκηςστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 30 δευτερόλεπτα
Journal of Cardiothoracic and Vascular Anesthesia from Emergency Medicine via xlomafota13 on Inoreader http://ift.tt/22oPHEB

Ilizarov arthrodesis as a salvage procedure in infected posttraumatic arthritic ankle: experience in 11 patients

Αλέξανδρος ΣφακιανάκηςστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 30 δευτερόλεπτα
Current Orthopaedic Practice from Emergency Medicine via xlomafota13 on Inoreader http://ift.tt/1TxVB65

Rapid Response Team activation in New Zealand hospitals: A multicentre prospective observational study

Αλέξανδρος ΣφακιανάκηςστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 30 δευτερόλεπτα
Anesthesia and Intensive Care from Emergency Medicine via xlomafota13 on Inoreader http://ift.tt/22oQ3Lo

Non-invasive mechanical ventilation in elderly patients: A narrative review

Αλέξανδρος ΣφακιανάκηςστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 30 δευτερόλεπτα
Geriatrics and Gerontology International from Emergency Medicine via xlomafota13 on Inoreader http://ift.tt/1TxVMhu

Statin-induced liver Injury in an area endemic for hepatitis B virus infection: Risk factors and outcome analysis

Αλέξανδρος ΣφακιανάκηςστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 30 δευτερόλεπτα
British Journal of Clinical Pharmacology from Emergency Medicine via xlomafota13 on Inoreader http://ift.tt/22oPZv4

Influence of volume administration on Doppler-based renal resistive index, renal hemodynamics and renal function in medical intensive care unit patients with septic-induced acute kidney injury: A pilot study

Αλέξανδρος ΣφακιανάκηςστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 30 δευτερόλεπτα
International Urology and Nephrology from Emergency Medicine via xlomafota13 on Inoreader http://ift.tt/1TxVesa

Evaluating posterior cruciate ligament injury by using two-dimensional ultrasonography and sonoelastography

Αλέξανδρος ΣφακιανάκηςστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 30 δευτερόλεπτα
Knee Surgery, Sports Traumatology, Arthroscopy from Emergency Medicine via xlomafota13 on Inoreader http://ift.tt/22oQ16p

Moderate traumatic brain injury, acute phase course and deviations in physiological variables: An observational study

Αλέξανδρος ΣφακιανάκηςστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 30 δευτερόλεπτα
Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine from Emergency Medicine via xlomafota13 on Inoreader http://ift.tt/1TxVCHd

Sustaining critical care: Using evidence-based simulation to evaluate ICU management policies

Αλέξανδρος ΣφακιανάκηςστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 30 δευτερόλεπτα
Health Care Management Science from Emergency Medicine via xlomafota13 on Inoreader http://ift.tt/22oQ4Pz

Reliability of a decision-tree model in predicting occupational lead poisoning in a group of highly exposed workers

Αλέξανδρος ΣφακιανάκηςστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 30 δευτερόλεπτα
American Journal of Industrial Medicine from Emergency Medicine via xlomafota13 on Inoreader http://ift.tt/1WSID3H

Rupture of internal pudendal artery aneurysm following spontaneous vaginal delivery: An uncommon cause of post-partum bleeding

Αλέξανδρος ΣφακιανάκηςστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 30 δευτερόλεπτα
Obstetric Medicine from Emergency Medicine via xlomafota13 on Inoreader http://ift.tt/1OMQmIj

Automatic radiation dose monitoring for CT of trauma patients with different protocols: Feasibility and accuracy

Αλέξανδρος ΣφακιανάκηςστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 30 δευτερόλεπτα
Clinical Radiology from Emergency Medicine via xlomafota13 on Inoreader http://ift.tt/1WSIyx6

Paper disc can quickly detect Zika virus in the field

Αλέξανδρος ΣφακιανάκηςστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 30 δευτερόλεπτα
Harvard Gazette - Health News from Emergency Medicine via xlomafota13 on Inoreader http://ift.tt/1OMQveA

Persistence of respiratory and inflammatory responses after dermal sensitization to persulfate salts in a mouse model of non-atopic asthma

Alexandros G. SfakianakisστοAllergy Rhinology Immunology AsthmaΠριν από 41 δευτερόλεπτα
Exposure to ammonium persulfate (AP) has been reported to be the main cause of occupational asthma in hairdressers. The aim of this study is to assess how long the asthmatic response to AP can be induced after... from Allergy and Immunology via xlomafota13 on Inoreader http://ift.tt/1Tygu0Y

Erratum to: Safety and feasibility of oral immunotherapy to multiple allergens for food allergy

Alexandros G. SfakianakisστοAllergy Rhinology Immunology AsthmaΠριν από 41 δευτερόλεπτα
from Allergy and Immunology via xlomafota13 on Inoreader http://ift.tt/1Udel7D

Primary immunodeficiencies associated with eosinophilia

Alexandros G. SfakianakisστοAllergy Rhinology Immunology AsthmaΠριν από 41 δευτερόλεπτα
Eosinophilia is not an uncommon clinical finding. However, diagnosis of its cause can be a dilemma once common culprits, namely infection, allergy and reactive causes are excluded. Primary immunodeficiency dis... from Allergy and Immunology via xlomafota13 on Inoreader http://ift.tt/1TygeyR

Grade school student made an honorary paramedic

Alexandros G. SfakianakisστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 42 δευτερόλεπτα
MIDHURST, Ontario — An elementary school student spent a day away from school as an honorary paramedic to learn about emergency services. Olivia Gater, a fifth grade student, submitted the winning essay for a National Paramedic Services Week contest to the County of Simcoe Paramedic Services. She received a certificate, first aid bag, and stethoscope before spending the day with a paramedic crew learning about the job. Gater read her winning essay to the Simcoe County councilors at the start of National Paramedic Services Week, reported Barrie Today. "Paramedics are essential to t... περισσότερα »

Quickstats: Age-adjusted suicide rates for females and males, by method - National Vital Statistics System, United States, 2000 and 2014

Alexandros G. SfakianakisστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 42 δευτερόλεπτα
Morbidity and Mortality Weekly Report from Emergency Medicine via xlomafota13 on Inoreader http://ift.tt/22oQ5mB via IFTTT

Acute heart failure with and without acute coronary syndrome: Clinical correlates and prognostic impact (From the HEARTS registry)

Alexandros G. SfakianakisστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 42 δευτερόλεπτα
BMC Cardiovascular Disorders from Emergency Medicine via xlomafota13 on Inoreader http://ift.tt/1TxVp6Q via IFTTT

Learning curves for ultrasound assessment of lumbar puncture insertion sites: When is competency established?

Alexandros G. SfakianakisστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 42 δευτερόλεπτα
The Journal of Emergency Medicine from Emergency Medicine via xlomafota13 on Inoreader http://ift.tt/22oPRfl via IFTTT

Development of a new Emergency Medicine Spinal Immobilization Protocol for trauma patients and a test of applicability by German emergency care providers

Alexandros G. SfakianakisστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 42 δευτερόλεπτα
Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine from Emergency Medicine via xlomafota13 on Inoreader http://ift.tt/1TxVoji via IFTTT

Remote preconditioning protects early renal functions in low risk cardiac surgery patients

Alexandros G. SfakianakisστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 42 δευτερόλεπτα
Journal of Cardiothoracic and Vascular Anesthesia from Emergency Medicine via xlomafota13 on Inoreader http://ift.tt/22oPHEB via IFTTT

Ilizarov arthrodesis as a salvage procedure in infected posttraumatic arthritic ankle: experience in 11 patients

Alexandros G. SfakianakisστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 42 δευτερόλεπτα
Current Orthopaedic Practice from Emergency Medicine via xlomafota13 on Inoreader http://ift.tt/1TxVB65 via IFTTT

Rapid Response Team activation in New Zealand hospitals: A multicentre prospective observational study

Alexandros G. SfakianakisστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 42 δευτερόλεπτα
Anesthesia and Intensive Care from Emergency Medicine via xlomafota13 on Inoreader http://ift.tt/22oQ3Lo via IFTTT

Non-invasive mechanical ventilation in elderly patients: A narrative review

Alexandros G. SfakianakisστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 42 δευτερόλεπτα
Geriatrics and Gerontology International from Emergency Medicine via xlomafota13 on Inoreader http://ift.tt/1TxVMhu via IFTTT

Statin-induced liver Injury in an area endemic for hepatitis B virus infection: Risk factors and outcome analysis

Alexandros G. SfakianakisστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 42 δευτερόλεπτα
British Journal of Clinical Pharmacology from Emergency Medicine via xlomafota13 on Inoreader http://ift.tt/22oPZv4 via IFTTT

Influence of volume administration on Doppler-based renal resistive index, renal hemodynamics and renal function in medical intensive care unit patients with septic-induced acute kidney injury: A pilot study

Alexandros G. SfakianakisστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 42 δευτερόλεπτα
International Urology and Nephrology from Emergency Medicine via xlomafota13 on Inoreader http://ift.tt/1TxVesa via IFTTT

Evaluating posterior cruciate ligament injury by using two-dimensional ultrasonography and sonoelastography

Alexandros G. SfakianakisστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 42 δευτερόλεπτα
Knee Surgery, Sports Traumatology, Arthroscopy from Emergency Medicine via xlomafota13 on Inoreader http://ift.tt/22oQ16p via IFTTT

Moderate traumatic brain injury, acute phase course and deviations in physiological variables: An observational study

Alexandros G. SfakianakisστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 42 δευτερόλεπτα
Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine from Emergency Medicine via xlomafota13 on Inoreader http://ift.tt/1TxVCHd via IFTTT

Sustaining critical care: Using evidence-based simulation to evaluate ICU management policies

Alexandros G. SfakianakisστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 42 δευτερόλεπτα
Health Care Management Science from Emergency Medicine via xlomafota13 on Inoreader http://ift.tt/22oQ4Pz via IFTTT

Reliability of a decision-tree model in predicting occupational lead poisoning in a group of highly exposed workers

Alexandros G. SfakianakisστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 42 δευτερόλεπτα
American Journal of Industrial Medicine from Emergency Medicine via xlomafota13 on Inoreader http://ift.tt/1WSID3H via IFTTT

Rupture of internal pudendal artery aneurysm following spontaneous vaginal delivery: An uncommon cause of post-partum bleeding

Alexandros G. SfakianakisστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 42 δευτερόλεπτα
Obstetric Medicine from Emergency Medicine via xlomafota13 on Inoreader http://ift.tt/1OMQmIj via IFTTT

Automatic radiation dose monitoring for CT of trauma patients with different protocols: Feasibility and accuracy

Alexandros G. SfakianakisστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 42 δευτερόλεπτα
Clinical Radiology from Emergency Medicine via xlomafota13 on Inoreader http://ift.tt/1WSIyx6 via IFTTT

Paper disc can quickly detect Zika virus in the field

Alexandros G. SfakianakisστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 42 δευτερόλεπτα
Harvard Gazette - Health News from Emergency Medicine via xlomafota13 on Inoreader http://ift.tt/1OMQveA via IFTTT

Identification report coins Harelbeke

from #MedicinebyAlexandrosSfakianakis via xlomafota13 on Inoreader http://ift.tt/1TWeKsG via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1TDUb6S via IFTTT

Brain trauma elicits non-canonical macrophage activation states

Macrophage polarization programs, commonly referred to as “classical” and “alternative” activation, are widely considered as distinct states that are exclusive of one another and are associated with different … from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1qJ7fgL via IFTTT

Inflammatory profile in LRRK2-associated prodromal and clinical PD

There is evidence for a relevant role of inflammation in the pathogenesis of Parkinson’s disease (PD). Mutations in the LRRK2 gene represent the most frequent genetic cause for autosomal dominant PD. LRRK2 is hig… from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1WijL4R via IFTTT

Gastric lap-band infection due to Mycobacterium abscessus presenting as new-onset ascites in a cirrhotic patient

10.3109/23744235.2016.1143116<br>Allon Kahn from #MedicinebyAlexandrosSfakianakis via xlomafota13 on Inoreader http://ift.tt/1Ty3jgs via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1TDUi2f via IFTTT

Remodeling of lipid bodies by docosahexaenoic acid in activated microglial cells

Organelle remodeling processes are evolutionarily conserved and involved in cell functions during development, aging, and cell death. Some endogenous and exogenous molecules can modulate these processes. Docos… from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1qJ7itd via IFTTT

Parvovirus B19 congenital infection

10.3109/23744235.2016.1163731<br>Raúl Gilarranz from #MedicinebyAlexandrosSfakianakis via xlomafota13 on Inoreader http://ift.tt/1Ud89fS via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1WSSsi0 via IFTTT

Effect of feeding mixed microbial culture fortified with trace minerals on ruminal fermentation, nutrient digestibility, nitrogen and trace mineral balance in Sheep

Background: The aim of the present study was to determine the effects of feeding trace mineralsfortified mixed microbial culture (TMC) on ruminal fermentation, nutrient digestibility, blood electrolyte status, nitrogen balance, and trace mineral balance in sheep. Methods: Mixed microbes [0.6 % (v/w) of Enterobacter sp., Bacillus sp., Lactobacillus sp., and Saccharomyces sp.] were cultured with 99 […]

Actualisation des recommandations pour la prise en charge et le suivi des patients asthmatiques : la Société de pneumologie de langue française garde le contrôle

Publication date: April 2016 Source:Revue des Maladies Respiratoires, Volume 33, Issue 4 Author(s): A. Didier, F. Chabot from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1Udc906 via IFTTT

The imidazoline compound RX871024 promotes insulinoma cell death independent of AMP-activated protein kinase inhibition

Alexandros G. SfakianakisστοΘεραπείαΠριν από 1 ώρα
Summary We have previously shown that the insulinotropic imidazoline compound RX871024 induces death of insulinoma MIN6 cells, an effect involving stimulation of c-Jun N-terminal kinase (JNK) and caspase 3. It has also been reported that AMP-activated protein kinase (AMPK) activates JNK and induces β-cell death. Here we show that RX871024, but not another insulinotropic imidazoline compound (BL11282), suppressed AMPK activity in MIN6 cells. The inhibitory effect of RX871024 on AMPK was supported by the observation that the imidazoline induced lipid droplet formation in the cytopla...περισσότερα »

Pharmacokinetics and excretion of 14 C-omacetaxine in patients with advanced solid tumors

Summary Background Omacetaxine mepesuccinate is indicated in adults with chronic myeloid leukemia resistant and/or intolerant to ≥ 2 tyrosine kinase inhibitor treatments. This phase I study assessed the disposition, elimination, and safety of 14C-omacetaxine in patients with solid tumors. Methods The study comprised a 7-days pharmacokinetic assessment followed by a treatment period of ≤ six 28-days cycles. A single […]

T-bet promotes the accumulation of encephalitogenic Th17 cells in the CNS

In this study we show that T-bet confers a competitive advantage for the accumulation of IL-23 conditioned Th17 effector cells in the central nervous system (CNS). Impaired migration of T-bet deficient Th17 cells to the CNS is associated with altered expression of adhesion molecules and chemokine receptors on their cell surface. Our data suggest that […]

Perception of hearing impairment and the willingness to use hearing aids in an elderly population in southern Taiwan: A community-based study.

Perception of hearing impairment and the willingness to use hearing aids in an elderly population in southern Taiwan: A community-based study. Int J Audiol. 2016 May 24;:1-8 Authors: Chang NC, Dai CY, Lin WY, Chien CY, Hsieh MH, Ho KY Abstract OBJECTIVES: To estimate the prevalence and severity of hearing impairment (HI), the self-perception of […]

Influence of contralateral acoustic hearing on adult bimodal outcomes after cochlear implantation.

Influence of contralateral acoustic hearing on adult bimodal outcomes after cochlear implantation. Int J Audiol. 2016 May 23;:1-11 Authors: Plant K, van Hoesel R, McDermott H, Dawson P, Cowan R Abstract OBJECTIVE: To examine post-implantation benefit and time taken to acclimate to the cochlear implant for adult candidates with more hearing in the contralateral non-implanted […]

Infektionskrankheiten bei Migranten erkennen & behandeln

Update Diagnostik und Therapie von Infektionen bei Migranten oder neu ankommenden Geflüchteten erfordern mitunter spezielle Kenntnisse, gegebenenfalls auch spezifische Schutzmaßnahmen. Wir bringen Sie auf den neuesten Stand. from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/25gBwDl via IFTTT

Influence of contralateral acoustic hearing on adult bimodal outcomes after cochlear implantation.

Influence of contralateral acoustic hearing on adult bimodal outcomes after cochlear implantation. Int J Audiol. 2016 May 23;:1-11 Authors: Plant K, van Hoesel R, McDermott H, Dawson P, Cowan R Abstract OBJECTIVE: To examine post-implantation benefit and time taken to acclimate to the cochlear implant for adult candidates with more hearing in the contralateral non-implanted […]

Noninvasive detection of enzyme activity in tumor models of human ovarian cancer using catalyCEST MRI

Purpose We proposed to detect the in vivo enzyme activity of γ-glutamyl transferase (GGT) within mouse models of human ovarian cancers using catalyCEST MRI with a diamagnetic CEST agent. Methods A CEST-FISP MRI protocol and a diamagnetic CEST agent were developed to detect GGT enzyme activity in biochemical solution. A quantitative Michaelis-Menten enzyme kinetics study […]

Influence of contralateral acoustic hearing on adult bimodal outcomes after cochlear implantation.

Influence of contralateral acoustic hearing on adult bimodal outcomes after cochlear implantation. Int J Audiol. 2016 May 23;:1-11 Authors: Plant K, van Hoesel R, McDermott H, Dawson P, Cowan R Abstract OBJECTIVE: To examine post-implantation benefit and time taken to acclimate to the cochlear implant for adult candidates with more hearing in the contralateral non-implanted […]

Highly efficient nonrigid motion-corrected 3D whole-heart coronary vessel wall imaging

Purpose To develop a respiratory motion correction framework to accelerate free-breathing three-dimensional (3D) whole-heart coronary lumen and coronary vessel wall MRI. Methods We developed a 3D flow-independent approach for vessel wall imaging based on the subtraction of data with and without T2-preparation prepulses acquired interleaved with image navigators. The proposed method corrects both datasets to […]

Perception of hearing impairment and the willingness to use hearing aids in an elderly population in southern Taiwan: A community-based study.

Perception of hearing impairment and the willingness to use hearing aids in an elderly population in southern Taiwan: A community-based study. Int J Audiol. 2016 May 24;:1-8 Authors: Chang NC, Dai CY, Lin WY, Chien CY, Hsieh MH, Ho KY Abstract OBJECTIVES: To estimate the prevalence and severity of hearing impairment (HI), the self-perception of […]

État des lieux de la prévention du risque cytotoxique au centre hospitalier de Niort : étude préliminaire dans le service de pneumologie

Publication date: Available online 24 May 2016 Source:Archives des Maladies Professionnelles et de l’Environnement Author(s): S. Nolin, J.-P. Decourt, I. Bourlaud, J. Druet ObjectifLe service de santé au travail du centre hospitalier de Niort a décidé de faire un état des lieux de la prévention du risque cytotoxique dans les services de soins.MéthodesL’infirmière de santé […]

Integrity or impact? Confessions of an early career researcher

A guest post from Dr Alecia Carter, Junior Research Fellow, Churchill College, University of Cambridge.

Focal Dystonia in Hemiplegic Upper Limb: Favorable Effect of Cervical Microsurgical DREZotomy Involving the Ventral Horn – A Report of 3 Patients

Background: Focal dystonia in hemiplegic upper limbs is poorly responsive to medications or classical neurosurgical treatments. Only repeated botulinum toxin injections show efficacy, but in most severe cases effects are transient. Objectives: Cervical DREZ lesioning, which has proven efficacious in hyperspasticity when done deeply (3-5 mm) in the dorsal horn, may have favorable effects on […]

Validity of self‐reported family history of cancer: A systematic literature review on selected cancers

In conclusion, for some cancers (e.g. pancreatic cancer, lung cancer, leukemia, lymphoma) self‐reported FHC can be considered sufficiently valid to be useful e.g. in preventive counseling. For several cancers, it is not sufficiently studied or the pattern is inconsistent. This needs to be taken into account when using self‐reported information about FHC in clinical practice […]

Peripubertal ovariectomy influences thymic adrenergic network plasticity in adult rats

The study investigated the influence of peripubertal ovariectomy on the thymic noradrenaline (NA) concentration, and the thymocyte NA content and β2- and α1-adrenoceptor (AR) expression in adult 2- and 11-month-old rats. In control rats, the thymic NA concentration increased with age. This increase reflected rise in the density of catecholamine (CA)-containing fluorescent nerve fibers and […]

Differential effects on glial activation by a direct versus an indirect thrombin inhibitor

Thrombin is a potent regulator of brain function in health and disease, modulating glial activation and brain inflammation. Thrombin inhibitors, several of which are in clinical use as anti-coagulants, can reduce thrombin-dependent neuroinflammation in pathological conditions. However, their effects in a healthy CNS are largely unknown. In adult healthy mice, we compared the effects of […]

Factors affecting return to oral intake in inpatient rehabilitation after acquired brain injury.

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 1 ώρα
[image: http:--http://ift.tt/1XLQsFQ] Related Articles *Factors affecting return to oral intake in inpatient rehabilitation after acquired brain injury.* Brain Inj. 2015;29(9):1094-104 Authors: Kjaersgaard A, Nielsen LH, Sjölund BH Abstract PRIMARY OBJECTIVE: To extend previous observations by investigating if differences exist in time to initiation or to recovery of total oral intake in patients with acquired brain injury assessed by either Facial-Oral Tract Therapy (F.O.T.T.) or Fibreoptic Endoscopic Evaluation of Swallowing (FEES) and to investigate whether other factors influ... περισσότερα »

20 years later: laparoscopic fundoplication durability.

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 1 ώρα
[image: http:--production.springer.de-OnlineReso] Related Articles *20 years later: laparoscopic fundoplication durability.* Surg Endosc. 2015 Sep;29(9):2520-4 Authors: Robinson B, Dunst CM, Cassera MA, Reavis KM, Sharata A, Swanstrom LL Abstract BACKGROUND: Laparoscopic surgery for gastrointestinal reflux disease was introduced in 1991. Early safety, efficacy, and 5-10-year durability have been amply documented, but long-term patient outcomes have been criticized. This study presents 20-year outcomes after laparoscopic fundoplication (LF) in a consecutive patient cohort. METHODS... περισσότερα »

[Stretch sphincter of the esophagus : Paradoxical sphincter with angiomyoelastic architecture].

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 1 ώρα
[image: http:--production.springer.de-OnlineReso] Related Articles *[Stretch sphincter of the esophagus : Paradoxical sphincter with angiomyoelastic architecture].* Chirurg. 2015 Aug;86(8):752-60 Authors: Stelzner F Abstract The investigations described in this article clearly show that the lower esophageal sphincter (LES) represents a variation of circular muscular occlusive mechanisms found elsewhere in the gastrointestinal tract. The LES is a double layer stretch sphincter that operates in an apparently paradoxical manner: it closes when under stretch but opens when the muscle... περισσότερα »

Speech-language Pathology in Acute Pediatric Chemical or Button Battery Ingestion Injury.

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 1 ώρα
*Speech-language Pathology in Acute Pediatric Chemical or Button Battery Ingestion Injury.* J Pediatr Gastroenterol Nutr. 2016 May 21; Authors: Follent AM, Rumbach AF, Ward EC, Dodrill P, Lewindon P Abstract OBJECTIVES: Dysphagia is a common consequence of pediatric ingestion injury, yet there is a lack of data relating to recommencement of oral (per os; PO) intake or use of feeding therapy. We describe patterns of early PO intake, and referral to speech-language pathology (SLP) for feeding therapy, during the acute admission of a pediatric cohort post-chemical or button battery ... περισσότερα »

Endoscopic treatment of Zenker's diverticulum with the stag beetle knife (sb knife) - feasibility and follow-up.

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 1 ώρα
*Endoscopic treatment of Zenker's diverticulum with the stag beetle knife (sb knife) - feasibility and follow-up.* Scand J Gastroenterol. 2016 May 24;:1-4 Authors: Goelder SK, Brueckner J, Messmann H Abstract BACKGROUND AND AIMS: Flexible endoscopic treatment of symptomatic Zenker's diverticulum (ZD) is an established treatment option. This study reports the first large cohort of ZD patients treated with the stag beetle knife (sb knife, a new scissor-like device) regarding feasibility, safety, and sustainability of mucomyotomy using this technique. METHODS: From August 2013 to Jan...περισσότερα »

Pharyngocutaneous Fistula Incidence After PMMC Patch Pharnygoplasty for Post Laryngectomy Defect Reconstruction - Predictive Factors, Our Experience at KMIO.

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 1 ώρα
*Pharyngocutaneous Fistula Incidence After PMMC Patch Pharnygoplasty for Post Laryngectomy Defect Reconstruction - Predictive Factors, Our Experience at KMIO.* Indian J Surg Oncol. 2015 Sep;6(3):223-6 Authors: Lakhera KK, Shenoy AM, Chavan P, Siddappa K Abstract To analyse pharyngocutaneous fistula, post Pectoralis major myocutaneous patch pharnygoplasty, and its association with various tumor, patient and treatment related factors. It is a retrospective study that included 48 patients who underwent laryngectomy and PMMC patch pharyngeal reconstruction from year 2009 to 2013. We ... περισσότερα »

Early diagnosis of oesophageal cancer improves outcomes.

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 1 ώρα
*Early diagnosis of oesophageal cancer improves outcomes.* Practitioner. 2016 Mar;260(1791):23-8, 3 Authors: Hopper AD, Campbell JA Abstract There are two main types of oesophageal cancer, oesophageal squamous cell carcinoma (OSCC) and oesophageal adenocarcinoma (OAC). They present in the same manner and both carry a five-year survival of only 16%. In the UK there is a 2:1 male to female ratio for oesophageal cancer. Peak incidence at presentation is in the 65-75 age group, with 95% of cases presenting in those over 50. Smoking is a major risk factor for both types and is linked ...περισσότερα »

CLINICAL PROBLEM-SOLVING. Eye of the Beholder.

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 1 ώρα
Related Articles *CLINICAL PROBLEM-SOLVING. Eye of the Beholder.* N Engl J Med. 2016 May 5;374(18):1774-9 Authors: MacFarlane L, Osman N, Ritter S, Miller AL, Loscalzo J PMID: 27144853 [PubMed - indexed for MEDLINE] from Swallowing and Swallowing Disorders (Dysphagia) via a.lsfakia on Inoreader http://ift.tt/247fYGQ via IFTTT

Reciprocal white matter alterations due to 16p11.2 chromosomal deletions versus duplications.

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 1 ώρα
*Reciprocal white matter alterations due to 16p11.2 chromosomal deletions versus duplications.* Hum Brain Mapp. 2016 May 24; Authors: Chang YS, Owen JP, Pojman NJ, Thieu T, Bukshpun P, Wakahiro ML, Marco EJ, Berman JI, Spiro JE, Chung WK, Buckner RL, Roberts TP, Nagarajan SS, Sherr EH, Mukherjee P Abstract Copy number variants at the 16p11.2 chromosomal locus are associated with several neuropsychiatric disorders, including autism, schizophrenia, bipolar disorder, attention-deficit hyperactivity disorder, and speech and language disorders. A gene dosage dependence has been sugges... περισσότερα »

[Paradoxical sphincters in the abdomen].

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 1 ώρα
[image: http:--production.springer.de-OnlineReso] Related Articles *[Paradoxical sphincters in the abdomen].* Chirurg. 2015 Aug;86(8):761-70 Authors: Stelzner F Abstract Nitric oxide molecules serve as neurotransmitters to relax smooth muscle tension in many parts of the body. In humans and other mammals they play an important role for correct smooth muscle function in unusual locations. We previously described this mechanism (Stelzner, Chirurg. doi:10.1007/s00104-014-2777-z, 2014) using the occlusive mechanism of the upper and lower esophageal sphincters as an example. Cells pro... περισσότερα »

Speech-language Pathology in Acute Pediatric Chemical or Button Battery Ingestion Injury.

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 1 ώρα
*Speech-language Pathology in Acute Pediatric Chemical or Button Battery Ingestion Injury.* J Pediatr Gastroenterol Nutr. 2016 May 21; Authors: Follent AM, Rumbach AF, Ward EC, Dodrill P, Lewindon P Abstract OBJECTIVES: Dysphagia is a common consequence of pediatric ingestion injury, yet there is a lack of data relating to recommencement of oral (per os; PO) intake or use of feeding therapy. We describe patterns of early PO intake, and referral to speech-language pathology (SLP) for feeding therapy, during the acute admission of a pediatric cohort post-chemical or button battery ... περισσότερα »

Development and application of cognitive-pragmatic language ability assessment protocol for traumatic brain injury.

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 1 ώρα
*Development and application of cognitive-pragmatic language ability assessment protocol for traumatic brain injury.* Appl Neuropsychol Adult. 2016 May 24;:1-13 Authors: Lee MS, Kim H Abstract The study aim was to introduce a newly-developed multifaceted cognitive-pragmatic language assessment protocol. This study was also designed to assess the reliability and validity of the assessment protocol in the discrimination between mild traumatic brain injury (mTBI) and normal control. Individuals in this study were 25 to 64 years old. Ten mTBIs and twenty-two control group were recrui...περισσότερα »

Structural language, pragmatic communication, behavior, and social competence in children adopted internationally: A pilot study.

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 1 ώρα
*Structural language, pragmatic communication, behavior, and social competence in children adopted internationally: A pilot study.* Appl Neuropsychol Child. 2016 May 23;:1-12 Authors: Petranovich CL, Walz NC, Staat MA, Chiu CP, Wade SL Abstract The objectives of this study were to examine the association of structural language and pragmatic communication with behavior problems and social competence in girls adopted internationally. Participants included girls between 6-12 years of age who were internationally adopted from China (n = 32) and Eastern-Europe (n = 25) and a control gr...περισσότερα »

How Does Word Length Evolve in Written Chinese?

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 1 ώρα
[image: http:--http://ift.tt/1II1iHB] [image: http:--http://ift.tt/1Fkw4zC] Related Articles *How Does Word Length Evolve in Written Chinese?* PLoS One. 2015;10(9):e0138567 Authors: Chen H, Liang J, Liu H Abstract We demonstrate a substantial evidence that the word length can be an essential lexical structural feature for word evolution in written Chinese. The data used in this study are diachronic Chinese short narrative texts with a time span of over 2000-years. We show that the increase of word length is an essential regularity in word evolution. On the one hand, word frequen... περισσότερα »

The attentional blink is related to phonemic decoding, but not sight-word recognition, in typically reading adults.

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 1 ώρα
[image: http:--linkinghub.elsevier.com-ihub-imag] Related Articles *The attentional blink is related to phonemic decoding, but not sight-word recognition, in typically reading adults.* Vision Res. 2015 Oct;115(Pt A):8-16 Authors: Tyson-Parry MM, Sailah J, Boyes ME, Badcock NA Abstract This research investigated the relationship between the attentional blink (AB) and reading in typical adults. The AB is a deficit in the processing of the second of two rapidly presented targets when it occurs in close temporal proximity to the first target. Specifically, this experiment examined wh... περισσότερα »

A preliminary psychometric evaluation of the interpersonal communication competence scale for aquired brain injury.

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 1 ώρα
[image: http:--http://ift.tt/1XLQsFQ] Related Articles *A preliminary psychometric evaluation of the interpersonal communication competence scale for aquired brain injury.* Brain Inj. 2015;29(9):1105-12 Authors: Hald SV, Baker FA, Ridder HM Abstract PRIMARY OBJECTIVE: To evaluate the psychometric properties of two adapted versions of the interpersonal communication competence scale (ICCS) that were applied to people with acquired brain injury (ABI). Construct validity was tested for both new scales and a factor extraction was performed on the proxy-rating version aiming to establ... περισσότερα »

Laparoscopic repeat hepatectomy after right hepatopancreaticoduodenectomy

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 1 ώρα
Abstract Although laparoscopic hepatectomy is widely accepted for primary hepatectomy, the clinical value of laparoscopic hepatectomy for repeat hepatectomy is still challenging. We herein describe our experience with laparoscopic repeat hepatectomy after right hepatopancreaticoduodenectomy. A 72-year-old woman who had undergone right hepatopancreaticoduodenectomy for perihilar cholangiocarcinoma 31 months prior was diagnosed with liver metastasis in segment 3. We performed laparoscopic repeat hepatectomy. Because mild adhesions in the left side of the abdominal cavity were detect... περισσότερα »

Expression of cysteinyl leukotriene receptor 1 and 2 (CysLTR1 and CysLTR2) in the lymphocytes of hyperplastic tonsils: comparison between allergic and nonallergic snoring children

Alexandros G. SfakianakisστοAllergy Rhinology Immunology AsthmaΠριν από 1 ώρα
Background Cysteinyl leukotriene receptor 1 and 2 (CysLTR1 and CysLTR2) are involved in allergic processes and play a role in adenotonsillar hyperplasia (AH). Clinically, only CysLTR1 may be blocked by montelukast. Our objective was to compare the expression of CysLTR1 and CysLTR2 in the B and T cells of hyperplasic tonsils of sensitized (SE) and control (NS) snoring children. Methods Sixty children, 5 to 10 years of age, referred for adenotonsillectomy, were divided into SE and NS groups, according to their responses to the skin-prick test. Cells from the removed tissues were st... περισσότερα »

Obstructive sleep apnea presenting as pseudopheochromocytoma.

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngolgy NewsΠριν από 1 ώρα
Related Articles *Obstructive sleep apnea presenting as pseudopheochromocytoma.* Pan Afr Med J. 2016;23:75 Authors: Marmouch H, Arfa S, Graja S, Slim T, Khochtali I Abstract A 52-year-old female with a history of poorly controlled resistant hypertension was admitted to our hospital with severe hypertension. She had a history of fatigue and intermittent episodes of palpitations. Laboratory evaluation was significant for elevated 24-h urinary catecholamine levels (3,5 times the upper normal levels). This case was presenting with a clinical and biochemical picture indistinguishable ... περισσότερα »

A Rare Case of Spontaneous Pneumocephalus Associated with Nontraumatic Cerebrospinal Fluid Leak.

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngolgy NewsΠριν από 1 ώρα
*A Rare Case of Spontaneous Pneumocephalus Associated with Nontraumatic Cerebrospinal Fluid Leak.* Case Rep Neurol Med. 2016;2016:1828461 Authors: Baba M, Tarar O, Syed A Abstract Introduction. Spontaneous nontraumatic pneumocephalus (PNC) and cerebrospinal fluid (CSF) leaks are both very uncommon conditions. We report a rare case of spontaneous pneumocephalus associated with CSF leak secondary to right sphenoid sinus bony defect without history of trauma. Case Description. 51-year-old Hispanic female with past medical history of hypertension and idiopathic intracranial hypertens... περισσότερα »

The nasofrontal beak: A consistent landmark for superior septectomy during Draf III drill out.

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngolgy NewsΠριν από 1 ώρα
*The nasofrontal beak: A consistent landmark for superior septectomy during Draf III drill out.* Am J Rhinol Allergy. 2016 May;30(3):230-4 Authors: Craig JR, Petrov D, Khalili S, Brooks SG, Lee JY, Adappa ND, Palmer JN Abstract INTRODUCTION: Cerebrospinal fluid (CSF) leak occurs in 1-11% of endoscopic Draf III, or endoscopic modified Lothrop, procedures. CSF leak can occur during surgery during a superior nasal septectomy. This study investigated whether the posterior edge of the nasofrontal beak (NFB) at the level of the internal frontal ostium is a safe landmark to use to avoid...περισσότερα »

Noninvasive Follicular Variant of Papillary Thyroid Carcinoma and the Afirma Gene-Expression Classifier.

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngolgy NewsΠριν από 1 ώρα
*Noninvasive Follicular Variant of Papillary Thyroid Carcinoma and the Afirma Gene-Expression Classifier.* Thyroid. 2016 May 24; Authors: Wong KS, Angell TE, Strickland KC, Alexander EK, Cibas E, Krane JF, Barletta J Abstract BACKGROUND: It is now recognized that noninvasive follicular variant of papillary thyroid carcinoma (NFVPTC) is a distinct subset of FVPTC with an exceedingly indolent clinical course. The Afirma gene-expression classifier (GEC) helps guide clinicians in the management of thyroid nodules with indeterminate fine needle aspiration (FNA) results. Thyroid surger...περισσότερα »

Stenting of the Lateral Sinus in Idiopathic Intracranial Hypertension According to the Type of Stenosis.

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngolgy NewsΠριν από 1 ώρα
*Stenting of the Lateral Sinus in Idiopathic Intracranial Hypertension According to the Type of Stenosis.* Neurosurgery. 2016 May 23; Authors: Lenck S, Vallée F, Labeyrie MA, Touitou V, Saint-Maurice JP, Guillonnet A, Tantot A, Crassard I, Bernat AL, Houdart E Abstract BACKGROUND: Over the past decade, stenting of lateral sinus stenosis has been used to treat idiopathic intracranial hypertension. Two types of stenoses have been identified: extrinsic and intrinsic. OBJECTIVE: The aim of this study was to report the results of our use of this procedure to treat patients with extrins... περισσότερα »

Neural Decoding of Discriminative Auditory Object Features Depends on Their Socio-Affective Valence.

Alexandros G. SfakianakisστοΦωνή κ' ΛόγοςΠριν από 1 ώρα
*Neural Decoding of Discriminative Auditory Object Features Depends on Their Socio-Affective Valence.* Soc Cogn Affect Neurosci. 2016 May 14; Authors: Frühholz S, van der Zwaag W, Saenz M, Belin P, Schobert AK, Vuilleumier P, Grandjean D Abstract Human voices consist of specific patterns of acoustic features that are considerably enhanced during affective vocalizations. These acoustic features are presumably used by listeners to accurately discriminate between acoustically or emotionally similar vocalizations. Here we used high-field 7T functional magnetic resonance imaging in hu... περισσότερα »

This is Not a History Lesson; This is Agitation: A Call for a Methodology of Diffraction in US-Based Community Psychology.

Alexandros G. SfakianakisστοΦωνή κ' ΛόγοςΠριν από 1 ώρα
*This is Not a History Lesson; This is Agitation: A Call for a Methodology of Diffraction in US-Based Community Psychology.* Am J Community Psychol. 2016 May 5; Authors: Langhout RD Abstract Agitation, as deployed by the Industrial Areas Foundation (IAF), occurs when imaginations and curiosities are piqued, and self-interest is made visible. In this framework, agitation is a step in creating change. In this paper, I outline two agitations within US-based community psychology. I then describe a third agitation that is underway; I add my voice and call for a methodology of diffract...περισσότερα »

Universal mechanisms of sound production and control in birds and mammals.

Alexandros G. SfakianakisστοΦωνή κ' ΛόγοςΠριν από 1 ώρα
[image: http:--http://ift.tt/1feGv2I] [image: http:--http://ift.tt/1Fkw4zC] Related Articles *Universal mechanisms of sound production and control in birds and mammals.* Nat Commun. 2015;6:8978 Authors: Elemans CP, Rasmussen JH, Herbst CT, Düring DN, Zollinger SA, Brumm H, Srivastava K, Svane N, Ding M, Larsen ON, Sober SJ, Švec JG Abstract As animals vocalize, their vocal organ transforms motor commands into vocalizations for social communication. In birds, the physical mechanisms by which vocalizations are produced and controlled remain unresolved because of the extreme difficul...περισσότερα »

Tinnitus.

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngolgy NewsΠριν από 2 ώρες
*Tinnitus.* JAMA. 2016 May 24;315(20):2221-2222 Authors: Walker DD, Cifu AS, Gluth MB PMID: 27218631 [PubMed - as supplied by publisher] from #ENT-PubMed via ola Kala on Inoreader http://ift.tt/1szGg8Q via IFTTT

Pharmacokinetics and excretion of 14 C-omacetaxine in patients with advanced solid tumors

Alexandros G. SfakianakisστοΘεραπείαΠριν από 2 ώρες
Summary *Background* Omacetaxine mepesuccinate is indicated in adults with chronic myeloid leukemia resistant and/or intolerant to ≥ 2 tyrosine kinase inhibitor treatments. This phase I study assessed the disposition, elimination, and safety of 14C-omacetaxine in patients with solid tumors. *Methods* The study comprised a 7-days pharmacokinetic assessment followed by a treatment period of ≤ six 28-days cycles. A single subcutaneous dose of 1.25 mg/m214C-omacetaxine was administered to six patients. Blood, urine, and feces were collected through 168 h or until radioactivity excrete...περισσότερα »

Next generation of carbon-monitoring satellites faces daunting hurdles

Space agencies envisage system of probes to track whether countries are achieving emissions goals. Nature 533 446 doi: 10.1038/533446a from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1NMg6tm via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 &amp; 00306932607174

Has a Hungarian physics lab found a fifth force of nature?

Radioactive decay anomaly could imply a new fundamental force, theorists say. Nature News doi: 10.1038/nature.2016.19957 from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1NMfB2p via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 &amp; 00306932607174

Reducing Perinatal Mortality in Nepal Using Helping Babies Breathe

BACKGROUND AND OBJECTIVE: Newborns are at the highest risk of dying around the time of birth, due to intrapartum-related complications. Our study’s objective was to improve adherence to the Helping Babies Breathe (HBB) neonatal resuscitation protocol and reduce perinatal mortality by using a quality improvement cycle (QIC) in a tertiary hospital in Nepal. METHODS: The […]

Prenatal Fish Oil Supplementation and Allergy: 6-Year Follow-up of a Randomized Controlled Trial

BACKGROUND AND OBJECTIVE: Evidence from randomized controlled trials in early infancy suggest that prenatal supplementation with -3 (n-3) long-chain polyunsaturated fatty acids (LCPUFA) reduces the incidence of allergic disease characterized by an immunoglobulin E (IgE) response. We aimed to determine whether protective effects were evident in the 6-year-old offspring of women supplemented with n-3 rich […]

Is adherence to diet, physical activity, and body weight cancer prevention recommendations associated with colorectal cancer incidence in African American women?

Conclusions Adherence to cancer prevention recommendations was low and not associated with colorectal cancer risk among women in the BWHS. Research in diverse populations is essential to evaluate the validity of existing recommendations, and assess whether there are alternative recommendations that are more beneficial for cancer prevention in specific populations. (Source: Cancer Causes and Control) […]

Can the response to a platinum-based therapy be predicted by the DNA repair status in non-small cell lung cancer?

Next generation sequencing techniques have accelerated disease gene identification and improved clinical diagnostics and targeted treatments options. With the advent of polygenic disease mechanisms involving cancer risk [1], comprehensive markers of pathogenic changes have become of paramount importance. DNA damage is the fundamental pathogenic event that triggers carcinogenesis. Different types of DNA lesions are known: […]

Omission of axillary dissection after a positive sentinel lymph-node: implications in the multidisciplinary treatment of operable breast cancer

Breast cancer mortality is continuously decreasing,[1] likely because of earlier diagnosis of resectable disease and improvements in management, in particular post-surgical treatments. The choice of these treatments, usually defined as “adjuvant”, relies upon an estimate of the individual risk of locoregional and distant relapse, events that these therapies aim to prevent.[2] Historically, axillary lymph-node dissection […]

Fluorescent probes for nanoscopy: four categories and multiple possibilities

Nanoscopy enables breaking down the light diffraction limit and reveals the nanostructures of objects being studied using light. In 2014, three scientists pioneered the development of nanoscopy and won the Nobel Prize in Chemistry. This recognized the achievement of the past twenty years in the field of nanoscopy. However, fluorescent probes used in the field […]

Which factors are associated with extremely short‐term survival after surgery in patients with esophageal squamous cell carcinoma?

ConclusionThe independent positive predictors for extremely short‐term survival are male gender, incomplete tumor resection and postoperative pulmonary infection besides higher pathological T stage and higher pathological N stage. (Source: Asia-Pacific Journal of Clinical Oncology) from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1OMNOd0 via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 &amp; 00306932607174

Re‐irradiation using proton beam therapy combined with weekly intra‐arterial chemotherapy for recurrent oral cancer

ConclusionRe‐irradiation using proton beam therapy combined with weekly intra‐arterial chemotherapy improved OS and local control rates compared with other treatment modalities and could become a new treatment modality for patients with recurrent oral cancer. (Source: Asia-Pacific Journal of Clinical Oncology) from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1WSEddi via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios […]

Perception of hearing impairment and the willingness to use hearing aids in an elderly population in southern Taiwan: A community-based study.

Αλέξανδρος ΣφακιανάκηςστοAudiology by Alexandros G. SfakianakisΠριν από 2 ώρες
*Perception of hearing impairment and the willingness to use hearing aids in an elderly population in southern Taiwan: A community-based study.* Int J Audiol. 2016 May 24;:1-8 Authors: Chang NC, Dai CY, Lin WY, Chien CY, Hsieh MH, Ho KY Abstract OBJECTIVES: To estimate the prevalence and severity of hearing impairment (HI), the self-perception of HI, and the willingness to use a hearing aid (HA) in the elderly population in southern Taiwan. DESIGN: This community-based study was performed in a metropolitan hospital. A questionnaire about the perception of HI and the willingness to ... περισσότερα »

Influence of contralateral acoustic hearing on adult bimodal outcomes after cochlear implantation.

Αλέξανδρος ΣφακιανάκηςστοAudiology by Alexandros G. SfakianakisΠριν από 2 ώρες
*Influence of contralateral acoustic hearing on adult bimodal outcomes after cochlear implantation.* Int J Audiol. 2016 May 23;:1-11 Authors: Plant K, van Hoesel R, McDermott H, Dawson P, Cowan R Abstract OBJECTIVE: To examine post-implantation benefit and time taken to acclimate to the cochlear implant for adult candidates with more hearing in the contralateral non-implanted ear than has been previously considered within local candidacy guidelines. DESIGN: Prospective, within-subject experimental design. STUDY SAMPLE: Forty postlingual hearing-impaired adult subjects with a contr... περισσότερα »

RFX transcription factors are essential for hearing in mice.

Αλέξανδρος ΣφακιανάκηςστοAudiology by Alexandros G. SfakianakisΠριν από 2 ώρες
[image: http:--http://ift.tt/1feGv2I] [image: http:--http://ift.tt/1Fkw4zC] Related Articles *RFX transcription factors are essential for hearing in mice.* Nat Commun. 2015;6:8549 Authors: Elkon R, Milon B, Morrison L, Shah M, Vijayakumar S, Racherla M, Leitch CC, Silipino L, Hadi S, Weiss-Gayet M, Barras E, Schmid CD, Ait-Lounis A, Barnes A, Song Y, Eisenman DJ, Eliyahu E, Frolenkov GI, Strome SE, Durand B, Zaghloul NA, Jones SM, Reith W, Hertzano R Abstract Sensorineural hearing loss is a common and currently irreversible disorder, because mammalian hair cells (HCs) do not regen... περισσότερα »

Challenges and solutions for gene identification in the presence of familial locus heterogeneity.

Αλέξανδρος ΣφακιανάκηςστοAudiology by Alexandros G. SfakianakisΠριν από 2 ώρες
[image: http:--http://ift.tt/1feGv2I] [image: http:--http://ift.tt/1Fkw4zC] Related Articles *Challenges and solutions for gene identification in the presence of familial locus heterogeneity.* Eur J Hum Genet. 2015 Sep;23(9):1207-15 Authors: Rehman AU, Santos-Cortez RL, Drummond MC, Shahzad M, Lee K, Morell RJ, Ansar M, Jan A, Wang X, Aziz A, Riazuddin S, Smith JD, Wang GT, Ahmed ZM, Gul K, Shearer AE, Smith RJ, Shendure J, Bamshad MJ, Nickerson DA, University of Washington Center for Mendelian Genomics, Hinnant J, Khan SN, Fisher RA, Ahmad W, Friderici KH, Riazuddin S, Friedman T...περισσότερα »

Speech-language Pathology in Acute Pediatric Chemical or Button Battery Ingestion Injury.

Alexandros G. SfakianakisστοSwallowing and Swallowing Disorders (Dysphagia)Πριν από 2 ώρες
*Speech-language Pathology in Acute Pediatric Chemical or Button Battery Ingestion Injury.* J Pediatr Gastroenterol Nutr. 2016 May 21; Authors: Follent AM, Rumbach AF, Ward EC, Dodrill P, Lewindon P Abstract OBJECTIVES: Dysphagia is a common consequence of pediatric ingestion injury, yet there is a lack of data relating to recommencement of oral (per os; PO) intake or use of feeding therapy. We describe patterns of early PO intake, and referral to speech-language pathology (SLP) for feeding therapy, during the acute admission of a pediatric cohort post-chemical or button battery ... περισσότερα »