Αρχειοθήκη ιστολογίου

Αλέξανδρος Γ. Σφακιανάκης
ΩτοΡινοΛαρυγγολόγος
Αναπαύσεως 5
Άγιος Νικόλαος Κρήτη 72100
2841026182
6032607174

Τετάρτη 23 Δεκεμβρίου 2015

OtoRhinoLaryngology & Medicine,New Articles,December 23rd,2015,a


Single-Stage Technique for Antihelix and Scapha Reconstruction

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 7 δευτερόλεπτα
The Postauricular Helix-based Adipodermal-pedicle Turnover (PHAT) Flap: An Original Single-Stage Technique for Antihelix and Scapha Reconstruction: [image: image]Background: In reconstructing anterior defects of the ear, postauricular flaps represent a popular option. The pedicle of such transauricular flaps can be superior, inferior, medial, or lateral. The postauricular helix-based adipodermal-pedicle turnover (PHAT) flap is an original single-stage transauricular technique for defects of the antihelix and scapha. Its skin paddle is on the posterior aspect of the ear. Its lateral ... περισσότερα »

The Postauricular Helix-based Adipodermal-pedicle Turnover (PHAT) Flap

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 7 δευτερόλεπτα
The Postauricular Helix-based Adipodermal-pedicle Turnover (PHAT) Flap: An Original Single-Stage Technique for Antihelix and Scapha Reconstruction: [image: image]Background: In reconstructing anterior defects of the ear, postauricular flaps represent a popular option. The pedicle of such transauricular flaps can be superior, inferior, medial, or lateral. The postauricular helix-based adipodermal-pedicle turnover (PHAT) flap is an original single-stage transauricular technique for defects of the antihelix and scapha. Its skin paddle is on the posterior aspect of the ear. Its lateral ... περισσότερα »

Hilar Vessels of the Submandibular and Upper Jugular Neck Lymph Nodes

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 8 δευτερόλεπτα
Hilar Vessels of the Submandibular and Upper Jugular Neck Lymph Nodes: Anatomical Study for Vascularized Lymph Node Transfer to Extremity Lymphedema: [image: image]Objectives: Vascularized lymph node transfer for lymphedema is an emerging method of treatment. Vascularized lymph nodes have been harvested from a number of donor sites, that is, groin, axilla, and neck. There is a concern that harvesting nodes from the groin and axilla may lead to donor site lymphedema. This risk is greatly reduced in harvesting from the neck due to the abundant supply of lymph nodes here. In this cadav...περισσότερα »

Three-Dimensional Approach to Zygoma Reduction

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 8 δευτερόλεπτα
Three-Dimensional Approach to Zygoma Reduction: Review of 221 Patients Over 7 Years: [image: image]Background: Zygoma reduction is commonly performed in Asian patients because a broad face is considered stubborn in appearance and unattractive. Consequently, a number of different techniques have been developed for zygoma reduction, the majority of which involve simple manipulations. However, no consensus has been reached on the optimal method. In the present report, we introduce a new method involving ostectomy and fixation that uses a 3-dimensional approach to zygoma reduction. Meth... περισσότερα »

Correction of Medial Blowout Fractures According to the Fracture Types

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 8 δευτερόλεπτα
Correction of Medial Blowout Fractures According to the Fracture Types: [image: image]Background: Regarding the issue of blowout fracture, a variety of approaches and surgical techniques have been reported to improve postoperative results. However, there are no extant guidelines for the selection of these various methods. The current authors classified the medial blowout fracture into 3 different types and adapted to suitable surgical techniques. Methods: Between October 2010 and March 2013, 89 patients who had medial blowout fracture were included in this study. We classified the st... περισσότερα »

Do Wound Cultures Give Information About the Microbiology of Blood Cultures in Severe Burn Patients?

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 8 δευτερόλεπτα
Do Wound Cultures Give Information About the Microbiology of Blood Cultures in Severe Burn Patients?: [image: image]Background: Blood stream infection (BSI) and the subsequent development of sepsis are among the most common infection complications occurring in severe burn patients. This study was designed to evaluate the relationship between the burn wound flora and BSI pathogens. Methods: Documentation of all bacterial and fungal wound and blood isolates from severe burn patients hospitalized in the burn unit and intensive care unit was obtained from medical records retrieved retrosp... περισσότερα »

Deep Inferior Epigastric Artery Perforator and Thoracoacromial Venous Supercharged Deep Inferior Epigastric Artery Perforator Flaps

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 9 δευτερόλεπτα
A Comparative Study Between Deep Inferior Epigastric Artery Perforator and Thoracoacromial Venous Supercharged Deep Inferior Epigastric Artery Perforator Flaps: [image: image] Background: Nowadays, microvascular breast reconstruction with abdominal perforator flap is a popular and widespread technique. However, venous congestion is a recurrent problem in deep inferior epigastric artery perforator (DIEP) flap survival. We present a venous supercharging technique using the thoracoacromial vein in DIEP free flap for breast reconstruction. Methods: A prospective randomized study was co...περισσότερα »

Postauricular Approach for Mandibular Angle Ostectomy

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 9 δευτερόλεπτα
Postauricular Approach for Mandibular Angle Ostectomy: An Alternative for Shortening the Recovery Time: [image: image]Abstract: Many surgical procedures to improve mandibular contour have been introduced in East Asia. Despite consensus regarding mandible contouring surgery, surgery which includes angle ostectomy and lateral cortex excision, some patients require only mandibular angle ostectomy. The intraoral approach is a widely used method, but has disadvantages with regard to the need for endotracheal intubation and patients are limited in their food intake for a considerable leng... περισσότερα »

A Standardized Method of Isolating Adipose-Derived Stem Cells for Clinical Applications

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 9 δευτερόλεπτα
A Standardized Method of Isolating Adipose-Derived Stem Cells for Clinical Applications: [image: image]Abstract: White adipose tissue is the most abundant and accessible source of stem cells in the adult human body. In this paper, we present a standardised and safe method of isolating and maximizing the number of adipose-derived stem cells (ASCs) from conventional liposuction for clinical applications, which was carried out through both mechanical (centrifuge) and enzymatic (collagenase) means. Isolated cells were characterized through flow cytometry assay. Gathered data showed a gr...περισσότερα »

Extracorporeal Septoplasty Combined With Valve Surgery in Rhinoplasty Patients

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 9 δευτερόλεπτα
Extracorporeal Septoplasty Combined With Valve Surgery in Rhinoplasty Patients: [image: image]Abstract: External nasal deviation is caused primarily by severely a deformed septum. The nose functions as a whole composed of the septum, valve systems, and mucosal structures. Patients with severely deviated septums also have deformed nasal valve systems. Extracorporeal septoplasty is advocated for an extremely deviated nasal septum. Nasal valve dysfunctions can be resolved successfully with spreader grafts. Application of extracorporeal septoplasty in combination with spreader grafts in...περισσότερα »

Reverse Superior Labial Artery Flap in Reconstruction of Nose and Medial Cheek Large Defects

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 9 δευτερόλεπτα
Reverse Superior Labial Artery Flap in Reconstruction of Nose and Medial Cheek Large Defects

The Dilator Naris Muscle as a Reporter of Facial Nerve Regeneration

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 9 δευτερόλεπτα
The Dilator Naris Muscle as a Reporter of Facial Nerve Regeneration in a Rat Model: [image: image] Objective: Many investigators study facial nerve regeneration using the rat whisker pad model, although widely standardized outcomes measures of facial nerve regeneration in the rodent have not yet been developed. The intrinsic whisker pad “sling” muscles producing whisker protraction, situated at the base of each individual whisker, are extremely small and difficult to study en bloc. Here, we compare the functional innervation of 2 potential reporter muscles for whisker pad innervati... περισσότερα »

Detailed Anatomy of the Nasolabial Muscle in Human Fetuses as Determined by Micro-CT Combined With Iodine Staining

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 11 δευτερόλεπτα
Detailed Anatomy of the Nasolabial Muscle in Human Fetuses as Determined by Micro-CT Combined With Iodine Staining: [image: image]Purpose: This study aims to investigate the 3-dimensional (3D) anatomical structure of the orbicularis oris and nasalis, which are closely associated with the appearance of the upper lip and lower part of the nose. The relationship of the complicated 3D anatomical structure with the outline shape was also determined. Methods: Microcomputed tomography combined with iodine staining was used to scan the nasolabial tissues of 3 aborted fetuses. The strictly al... περισσότερα »

American Board of Dermatology Examination Dates

Alexandros G. SfakianakisστοCell and Tissue Research by Alexandros G. SfakianakisΠριν από 12 δευτερόλεπτα
from Anatomy Pathology via xlomafota13 on Inoreader http://ift.tt/1kgT932 via IFTTT

Multiple cutaneous collagenomas in the setting of multiple endocrine neoplasia type 1

Alexandros G. SfakianakisστοCell and Tissue Research by Alexandros G. SfakianakisΠριν από 12 δευτερόλεπτα
from Anatomy Pathology via xlomafota13 on Inoreader http://ift.tt/1Iq6r97 via IFTTT

The development and testing of a skin tear risk assessment tool

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 12 δευτερόλεπτα
The development and testing of a skin tear risk assessment tool: Abstract The aim of the present study is to develop a reliable and valid skin tear risk assessment tool. The six characteristics identified in a previous case control study as constituting the best risk model for skin tear development were used to construct a risk assessment tool. The ability of the tool to predict skin tear development was then tested in a prospective study. Between August 2012 and September 2013, 1466 tertiary hospital patients were assessed at admission and followed up for 10 days to see if they de... περισσότερα »

Interesting facts regarding the marginal mandibular branch of the facial nerve

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 12 δευτερόλεπτα
Interesting facts regarding the marginal mandibular branch of the facial nerve: *Farida Hussan, Srijit Das* Indian Journal of Plastic Surgery 2010 43(2):231-231 Sir, We read with much interest the article titled 'Marginal branch of the facial nerve: An anatomical study' by Batra et al. [1] The cadaveric study describes the topographical anatomy of the marginal mandibular branch (MMB) of the facial nerve. We too would like to share some important facts related to the nerve branch. According to standard textbook of anatomy, the MMB bears an important relationship with the lo... περισσότερα »

Port retrieval for salvage of tissue expansion in case of lost or malfunctioning port

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 12 δευτερόλεπτα
Port retrieval for salvage of tissue expansion in case of lost or malfunctioning port: *Lalit K Makhija, Manoj K Jha, Sameek Bhattacharya, Ashish Rai, Sharad Mishra, Anjubala Dey* Indian Journal of Plastic Surgery 2010 43(2):181-183 Tissue expansion though a promising modality of reconstructive surgery is fraught with many complications. In addition to expander-related complications, subcutaneous port-related mishaps during tissue expansion, though infrequent, can result in procedure failures. We are reporting two patients with port-related complications. In one patient, there w... περισσότερα »

Behavioral Sciences, Vol. 6, Pages 1: Adolescent Pornography Use and Dating Violence among a Sample of Primarily Black and Hispanic, Urban-Residing, Underage Youth

Αλέξανδρος ΣφακιανάκηςστοMedicine by Alexandros G.SfakianakisΠριν από 14 δευτερόλεπτα
This cross-sectional study was designed to characterize the pornography viewing preferences of a sample of U.S.-based, urban-residing, economically disadvantaged, primarily Black and Hispanic youth (n = 72), and to assess whether pornography use was associated with experiences of adolescent dating abuse (ADA) victimization. The sample was recruited from a large, urban, safety net hospital, and participants were 53% female, 59% Black, 19% Hispanic, 14% Other race, 6% White, and 1% Native American. All were 16–17 years old. More than half (51%) had been asked to watch pornography to... περισσότερα »

Minerals, Vol. 6, Pages 1: New Insights in the Ontogeny and Taphonomy of the Devonian Acanthodian Triazeugacanthus affinis From the Miguasha Fossil-Lagerstätte, Eastern Canada

Αλέξανδρος ΣφακιανάκηςστοMedicine by Alexandros G.SfakianakisΠριν από 14 δευτερόλεπτα
Progressive biomineralization of a skeleton occurs during ontogeny in most animals. In fishes, larvae are poorly mineralized, whereas juveniles and adults display a progressively more biomineralized skeleton. Fossil remains primarily consist of adult specimens because the fossilization of poorly-mineralized larvae and juveniles necessitates exceptional conditions. The Miguasha Fossil-Lagerstätte is renowned for its Late Devonian vertebrate fauna, revealing the exceptional preservation of fossilized ontogenies for 14 of the 20 fish species from this locality. The mineralization of ... περισσότερα »

Algorithms, Vol. 9, Pages 2: Offset-Assisted Factored Solution of Nonlinear Systems

Αλέξανδρος ΣφακιανάκηςστοMedicine by Alexandros G.SfakianakisΠριν από 14 δευτερόλεπτα
This paper presents an improvement to the recently-introduced factored method for the solution of nonlinear equations. The basic idea consists of transforming the original system by adding an offset to all unknowns. When searching for real solutions, a real offset prevents the intermediate values of unknowns from becoming complex. Reciprocally, when searching for complex solutions, a complex offset is advisable to allow the iterative process to quickly abandon the real domain. Several examples are used to illustrate the performance of the proposed algorithm, when compared to Newto... περισσότερα »

High inspired oxygen versus low inspired oxygen for reducing surgical site infection

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 14 δευτερόλεπτα
High inspired oxygen versus low inspired oxygen for reducing surgical site infection: a meta-analysis: Abstract To perform a meta-analysis of published literature to assess the role of high-concentration inspired oxygen in reducing the incidence of surgical site infections (SSIs) following all types of surgery, a comprehensive search for published randomized controlled trials (RCTs) comparing high- with low-concentration inspired oxygen for SSIs was performed. The related data were extracted by two independent authors. The fixed and random effects methods were used to combine data.... περισσότερα »

Effectively Axonal-supercharged Interpositional Jump-Graft with an Artificial Nerve Conduit for Rat Facial Nerve Paralysis

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 14 δευτερόλεπτα
Effectively Axonal-supercharged Interpositional Jump-Graft with an Artificial Nerve Conduit for Rat Facial Nerve Paralysis: [image: image] Background: Interpositional jump graft (IPJG) is a nerve graft axonally supercharged from the hypoglossal nerve. However, for using the technique, an autologous nerve, which should contain the great auricular and sural nerves, must be obtained. Depending on the donor site, unavoidable issues such as nerve disorders and postoperative scarring may appear. To reduce the issues, in this study, the authors developed an end-to-side neurorrhaphy techni... περισσότερα »

Current Oncology Reports, Vol. 17, Issue 12 - New Issue Alert

Alexandros G. SfakianakisστοOnline Medical Journals by Alexandros G.SfakianakisΠριν από 19 δευτερόλεπτα
If this email is not displayed correctly, please click here to read this table of contents online. New Issue Alert 12/23/2015 Dear Alexandros Sfakianakis, We are pleased to deliver your requested table of contents alert for *Current Oncology Reports*. Volume 17 Number 12 is now available online. Important news Papers, the reference manager, for iPhone and iPad now totally free Full functionality, no in-app purchases or small print. Find, organize, read and share the research materials you care about, anytime, anywhere. Download today: http://papersapp.com/ios. » Learn more In... περισσότερα »

Effect of Two Isolated Vocal-facilitating Techniques Chant Talk and Pitch Inflections on the Phonation of Female Speech-language Pathology Students: A Pilot Study

Publication date: Available online 22 December 2015 Source:Journal of Voice Author(s): Iris Meerschman, Kim Bettens, Stefanie Dejagere, Lieselot Tetaert, Evelien D’haeseleer, Sofie Claeys, Kristiane Van Lierde ObjectiveThe purpose of this study was to determine the effect of the isolated vocal-facilitating techniques Chant Talk and Pitch Inflections on the phonation of healthy female speech-language pathology (SLP) […]

Prevalence and Influencing Risk Factors of Voice Problems in Priests in Kerala

Publication date: Available online 22 December 2015 Source:Journal of Voice Author(s): Usha Devadas, Navya Jose, Dhanshree Gunjawate ObjectiveVoice problems are commonly reported by professionals in occupations involving a large amount of voice loading. The aim of the present study was to investigate the prevalence of voice problems in Mar Thoma priests and identify possible risk […]

Effect of Two Isolated Vocal-facilitating Techniques Chant Talk and Pitch Inflections on the Phonation of Female Speech-language Pathology Students: A Pilot Study

Publication date: Available online 22 December 2015 Source:Journal of Voice Author(s): Iris Meerschman, Kim Bettens, Stefanie Dejagere, Lieselot Tetaert, Evelien D’haeseleer, Sofie Claeys, Kristiane Van Lierde ObjectiveThe purpose of this study was to determine the effect of the isolated vocal-facilitating techniques Chant Talk and Pitch Inflections on the phonation of healthy female speech-language pathology (SLP) […]

Comparison of Supraglottic Activity and Spectral Slope Between Theater Actors and Vocally Untrained Subjects

Publication date: Available online 22 December 2015 Source:Journal of Voice Author(s): Marco Guzman, Andres Ortega, Christian Olavarria, Daniel Muñoz, Pedro Cortés, Maria Josefina Azocar, David Cayuleo, Felipe Quintana, Catalina Silva PurposeThe present study aimed to assess supraglottic activity in theater actors and to observe whether they present differences compared with subjects with no voice training. […]

Prevalence and Influencing Risk Factors of Voice Problems in Priests in Kerala

Publication date: Available online 22 December 2015 Source:Journal of Voice Author(s): Usha Devadas, Navya Jose, Dhanshree Gunjawate ObjectiveVoice problems are commonly reported by professionals in occupations involving a large amount of voice loading. The aim of the present study was to investigate the prevalence of voice problems in Mar Thoma priests and identify possible risk […]

Comparison of Supraglottic Activity and Spectral Slope Between Theater Actors and Vocally Untrained Subjects

Publication date: Available online 22 December 2015 Source:Journal of Voice Author(s): Marco Guzman, Andres Ortega, Christian Olavarria, Daniel Muñoz, Pedro Cortés, Maria Josefina Azocar, David Cayuleo, Felipe Quintana, Catalina Silva PurposeThe present study aimed to assess supraglottic activity in theater actors and to observe whether they present differences compared with subjects with no voice training. […]

Obesity over the life course and risk of acute myeloid leukemia and myelodysplastic syndromes

Publication date: February 2016 Source:Cancer Epidemiology, Volume 40 Author(s): Jenny N. Poynter, Michaela Richardson, Cindy K. Blair, Michelle A. Roesler, Betsy A. Hirsch, Phuong Nguyen, Adina Cioc, Erica Warlick, James R. Cerhan, Julie A. Ross BackgroundOverweight and obesity are known risk factors for a number of cancers, with recent evidence suggesting that risk of hematologic […]

Patients’ strategies for eating after gastric bypass surgery: a qualitative study

Patients’ strategies for eating after gastric bypass surgery: a qualitative study European Journal of Clinical Nutrition advance online publication, December 23 2015. doi:10.1038/ejcn.2015.212 Authors: L Hillersdal, B J Christensen & L Holm from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1kgMsOA via IFTTT

Impact of weekly iron folic acid supplementation with and without vitamin B12 on anaemic adolescent girls: a randomised clinical trial

Impact of weekly iron folic acid supplementation with and without vitamin B12 on anaemic adolescent girls: a randomised clinical trial European Journal of Clinical Nutrition advance online publication, December 23 2015. doi:10.1038/ejcn.2015.215 Authors: P G Bansal, G S Toteja, N Bhatia, N K Vikram & A Siddhu from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1Sba0lC via […]

Cardiac arrest

New references from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1mA1Rez via IFTTT

Immunosuppressive therapy : Practical considerations for the use of mTOR inhibitors

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 22 δευτερόλεπτα
Practical considerations for the use of mTOR inhibitors: AbstractImmunosuppressive therapy after kidney transplantation is based on calcineurin inhibitors (CNI). In most cases CNI therapy is combined with mycophenolate and steroids. In spite of good short-term results this therapy is associated with long-term toxicities, graft loss and patient death. Therefore, alternative immunosuppressive strategies are needed that combine excellent efficacy with low incidences of long-term adverse outcomes. This review focuses on the strategies based on mTOR- inhibitors in combination with mini...περισσότερα »

Effect of Two Isolated Vocal-facilitating Techniques Chant Talk and Pitch Inflections on the Phonation of Female Speech-language Pathology Students: A Pilot Study

Publication date: Available online 22 December 2015 Source:Journal of Voice Author(s): Iris Meerschman, Kim Bettens, Stefanie Dejagere, Lieselot Tetaert, Evelien D’haeseleer, Sofie Claeys, Kristiane Van Lierde ObjectiveThe purpose of this study was to determine the effect of the isolated vocal-facilitating techniques Chant Talk and Pitch Inflections on the phonation of healthy female speech-language pathology (SLP) […]

Prevalence and Influencing Risk Factors of Voice Problems in Priests in Kerala

Publication date: Available online 22 December 2015 Source:Journal of Voice Author(s): Usha Devadas, Navya Jose, Dhanshree Gunjawate ObjectiveVoice problems are commonly reported by professionals in occupations involving a large amount of voice loading. The aim of the present study was to investigate the prevalence of voice problems in Mar Thoma priests and identify possible risk […]

Comparison of Supraglottic Activity and Spectral Slope Between Theater Actors and Vocally Untrained Subjects

Publication date: Available online 22 December 2015 Source:Journal of Voice Author(s): Marco Guzman, Andres Ortega, Christian Olavarria, Daniel Muñoz, Pedro Cortés, Maria Josefina Azocar, David Cayuleo, Felipe Quintana, Catalina Silva PurposeThe present study aimed to assess supraglottic activity in theater actors and to observe whether they present differences compared with subjects with no voice training. […]

Relationship Between Voice and Motor Disabilities of Parkinson’s Disease

Publication date: Available online 22 December 2015 Source:Journal of Voice Author(s): Fatemeh Majdinasab, Siamak Karkheiran, Majid Soltani, Negin Moradi, Gholamali Shahidi To evaluate voice of Iranian patients with Parkinson’s disease (PD) and find any relationship between motor disabilities and acoustic voice parameters as speech motor components. We evaluated 27 Farsi-speaking PD patients and 21 age- […]

Acoustic Analysis of Persian Vowels in Cochlear Implant Users: A Comparison With Hearing-impaired Children Using Hearing Aid and Normal-hearing Children

Publication date: Available online 22 December 2015 Source:Journal of Voice Author(s): Narges Jafari, Fariba Yadegari, Shohreh Jalaie ObjectiveVowel production in essence is auditorily controlled; hence, the role of the auditory feedback in vowel production is very important. The purpose of this study was to compare formant frequencies and vowel space in Persian-speaking deaf children with […]

Exploring Attitudes of Indian Classical Singers Toward Seeking Vocal Health Care

Publication date: Available online 23 December 2015 Source:Journal of Voice Author(s): Dhanshree R. Gunjawate, Venkataraja U. Aithal, Vasudeva Guddattu, Amrutha Kishore, Rajashekhar Bellur ObjectiveThe attitude of Indian classical singers toward seeking vocal health care is a dimension yet to be explored. The current study was aimed to determine the attitudes of these singers toward seeking […]

Physiology and Acoustics of Inspiratory Phonation

Publication date: Available online 22 December 2015 Source:Journal of Voice Author(s): Françoise Vanhecke, Jean Lebacq, Mieke Moerman, Claudia Manfredi, Godfried-Willem Raes, Philippe H. DeJonckere IntroductionInspiratory phonation (IP) means phonating with inspiratory airflow. Some vocalists remarkably master this technique, to such an extent that it offers new dramatic, aesthetic, and functional possibilities in singing specific contemporary […]

Coping strategies and cancer incidence and mortality: The Japan Public Health Center-based prospective study

Publication date: February 2016 Source:Cancer Epidemiology, Volume 40 Author(s): Thomas Svensson, Manami Inoue, Norie Sawada, Hadrien Charvat, Motoki Iwasaki, Shizuka Sasazuki, Taichi Shimazu, Taiki Yamaji, Noriyuki Kawamura, Kenji Shibuya, Masaru Mimura, Shoichiro Tsugane BackgroundPsychological stress is a modifiable risk factor for health outcomes and can be managed through coping mechanisms. Biological and behavioral hypotheses have […]

Coping strategies and cancer incidence and mortality: The Japan Public Health Center-based prospective study

Publication date: February 2016 Source:Cancer Epidemiology, Volume 40 Author(s): Thomas Svensson, Manami Inoue, Norie Sawada, Hadrien Charvat, Motoki Iwasaki, Shizuka Sasazuki, Taichi Shimazu, Taiki Yamaji, Noriyuki Kawamura, Kenji Shibuya, Masaru Mimura, Shoichiro Tsugane BackgroundPsychological stress is a modifiable risk factor for health outcomes and can be managed through coping mechanisms. Biological and behavioral hypotheses have […]

Obesity over the life course and risk of acute myeloid leukemia and myelodysplastic syndromes

Publication date: February 2016 Source:Cancer Epidemiology, Volume 40 Author(s): Jenny N. Poynter, Michaela Richardson, Cindy K. Blair, Michelle A. Roesler, Betsy A. Hirsch, Phuong Nguyen, Adina Cioc, Erica Warlick, James R. Cerhan, Julie A. Ross BackgroundOverweight and obesity are known risk factors for a number of cancers, with recent evidence suggesting that risk of hematologic […]

Airborne organophosphate pesticides drift in Mediterranean climate

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 24 δευτερόλεπτα
: The importance of secondary drift via ScienceDirect Publication: Atmospheric Environment [image: S13522310.gif] Publication date: February 2016 *Source:*Atmospheric Environment, Volume 127 Author(s): Ohad Zivan, Michal Segal-Rosenheimer, Yael Dubowski Pesticide application is a short-term air-pollution episode with near and far field effects due to atmospheric drift. In order to better evaluate resulting air concentrations in nearby communities following pesticide application, measurements of airborne pesticides were conducted at ∼70 m from field edge. This was done following three ... περισσότερα »

Carotid intima-media thickness and carotid arterial stiffness in children with adenotonsillar hypertrophy

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 27 δευτερόλεπτα
Evaluation of carotid intima-media thickness and carotid arterial stiffness in children with adenotonsillar hypertrophy: Abstract BackgroundAdenotonsillar hypertrophy can produce cardiopulmonary disease in children. However, it is unclear whether adenotonsillar hypertrophy causes atherosclerosis. This study evaluated carotid intimamedia thickness and carotid arterial stiffness in children with adenotonsillar hypertrophy. MethodsThe study included 40 children with adenotonsillar hypertrophy (age: 5-10 years) and 36 healthy children with similar age and body mass index. Systolic ... περισσότερα »

Detection of respiratory viruses and bacteria in children

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 27 δευτερόλεπτα
Detection of respiratory viruses and bacteria in children using a twenty-two target reverse-transcription real-time PCR (RT-qPCR) panel: Abstract BackgroundRapid detection of the wide range of viruses and bacteria that cause respiratory infection in children is important for patient care and antibiotic stewardship. We therefore designed and evaluated a readyto- use 22 target respiratory infection reverse-transcription real-time polymerase chain reaction (RT-qPCR) panel to determine if this would improve detection of these agents at our pediatric hospital. MethodsRT-qPCR assays ... περισσότερα »

Effect of zinc supplementation on infants with severe pneumonia

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 27 δευτερόλεπτα
Effect of zinc supplementation on infants with severe pneumonia: Abstract BackgroundPneumonia is a common respiratory infectious disease in infancy. Previous work shows controversial results on the benefit of zinc supplementation in patients with pneumonia. We conducted this study to investigate serum zinc status amongst infants with severe pneumonia and the clinical impact that zinc supplementation has on those patients with low serum zinc levels. MethodsThis study design was a non-blinded prospective randomized controlled trial. The study is approved by the Ethics Committees ... περισσότερα »

Nottingham Eczema Severity Score (NESS) : Predicting eczema severity beyond childhood

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 27 δευτερόλεπτα
Predicting eczema severity beyond childhood: Abstract BackgroundWe evaluated factors associated with eczema severity in adolescence. MethodsNottingham Eczema Severity Score (NESS), family and personal history of atopy, skin prick test for common food and aeroallergens, highest serum IgE level and eosinophil count were evaluated. Patients with paired NESSs (childhood-NESS is NESS performed at <10 years of age; adolescence-NESS is NESS performed at age >10 years) were further analyzed. ResultsAdolescence-NESS (*n*=383 patients) was associated with eczema onset in infancy, dus... περισσότερα »

Thyroid dysfunction and developmental anomalies in first degree relatives of children with thyroid dysgenesis

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 27 δευτερόλεπτα
Thyroid dysfunction and developmental anomalies in first degree relatives of children with thyroid dysgenesis: Abstract BackgroundFamilial clustering in patients with permanent congenital hypothyroidism (CH) caused by thyroid dysgenesis (TD) has been reported in developed countries. There is no information on familial TD from developing countries. MethodsA total of 312 first degree relatives belonging to 80 families of children with TD (group 1) and 40 families of age-matched normal children (group 2) were screened by thyroid ultrasonography, serum total thyroxine (T4) and thy... περισσότερα »

Medication errors

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 27 δευτερόλεπτα
New technologies as a strategy to decrease medication errors: how do they affect adults and children differently?: Abstract BackgroundMedication error can occur throughout the drug treatment process, with special relevance in children given the risk of adverse effects resulting from a medication error is more prevalent than in adults. The significance of medication error in children is also greater because small error that would be tolerated in adults can cause significant damage in children. Moreover, the likelihood of injury is higher than in adults. MethodsBased on the data ... περισσότερα »

Focal seizure associated with human parvovirus B19 infection in a non-encephalopathic child

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 27 δευτερόλεπτα
Focal seizure associated with human parvovirus B19 infection in a non-encephalopathic child: Abstract BackgroundThe incidence of acute symptomatic (at the time of documented brain insult) seizures and single unprovoked seizures are 29-39 and 23-61 per 100 000 per year, respectively. After stabilization of the patient, finding the etiology of the seizure is of paramount importance. A careful history and physical examination may allow a diagnosis without need for further evaluation. MethodsIn the literature, severe central nervous system involvement has been reported from human ... περισσότερα »

Respiratory Health Effects of Ultrafine Particles in Children

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 27 δευτερόλεπτα
Respiratory Health Effects of Ultrafine Particles in Children: a Literature Review: AbstractBy convention, airborne particles ≤0.1 μm (100 nm) are defined as ultrafine particles (UFPs). UFPs can comprise a large number of particles in particulate matter with aerodynamic diameters ≤2.5 μm (PM2.5). Despite the documented respiratory health effects of PM2.5 and concerns that UFPs might be more toxic than larger particular matter, the effects of UFPs on the respiratory system are not well-described. Even less is known about the respiratory health effects of UFPs among particularly vuln... περισσότερα »

Neuroprotection and Neurogenesis in the Neonatal Rat Brain After Stroke: Acute Blockage of Notch Signaling by DAPT

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 27 δευτερόλεπτα
Acute Blockage of Notch Signaling by DAPT Induces Neuroprotection and Neurogenesis in the Neonatal Rat Brain After Stroke: AbstractNotch signaling is critically involved in various biological events. Notch undergoes cleavage by the γ-secretase enzyme to release Notch intracellular domain that will translocate into nucleus to result in expression of target gene. γ-Secretase inhibitors have been developed as potential treatments for neurological degenerative diseases, but its effects against ischemic injury remain relatively uncertain. In the present study, we demonstrated that *N*-[... περισσότερα »

Acute Blockage of Notch Signaling by DAPT Induces Neuroprotection and Neurogenesis in the Neonatal Rat Brain After Stroke

Alexandros G. SfakianakisστοΝευρολογία κ' ΝευροχειρουργικήΠριν από 27 δευτερόλεπτα
Abstract Notch signaling is critically involved in various biological events. Notch undergoes cleavage by the γ-secretase enzyme to release Notch intracellular domain that will translocate into nucleus to result in expression of target gene. γ-Secretase inhibitors have been developed as potential treatments for neurological degenerative diseases, but its effects against ischemic injury remain relatively uncertain. In the present study, we demonstrated that *N*-[*N*-(3, 5-difluorophenacetyl)-l-alanyl]-*S*-phenylglycine *t*-butyl ester (DAPT), a γ-secretase inhibitor not only rescued...περισσότερα »

Pediatric gastrostomy tube placement techniques

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 30 δευτερόλεπτα
A comparison of pediatric gastrostomy tube placement techniques: Abstract PurposeThis study aimed to compare different techniques for placement of gastrostomy tubes in a pediatric population. Study designA retrospective review was performed for patients less than 18 years of age who underwent gastrostomy tube placement at a single academic children’s hospital between 2010 and 2012. Techniques for gastrostomy placement included Open Stamm, percutaneous endoscopic gastrostomy (PEG), fluoroscopy guided, laparoscopic, and laparoscopic assisted PEG. Pre-operative characteristics of ...περισσότερα »

Compliance with recommendations on surgery for primary hyperparathyroidism

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 30 δευτερόλεπτα
Compliance with recommendations on surgery for primary hyperparathyroidism—from guidelines to real practice: results from an Iberian survey: Abstract PurposeKnowledge about compliance with recommendations derived from the positional statement of the European Society of Endocrine Surgeons on modern techniques in primary hyperparathyroidism surgery and the Third International Workshop on management of asymptomatic primary hyperparathyroidism is scarce. Our purpose was to check it on a bi-national basis and determine whether management differences may have impact on surgical outcome... περισσότερα »

Conservative management of severe caustic injuries

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 30 δευτερόλεπτα
Conservative management of severe caustic injuries during acute phase leads to superior long-term nutritional and quality of life (QoL) outcome: Abstract PurposeBest clinical management of severe caustic injury is still a subject of debate. Most surgical teams consider severe caustic injury as an indication for emergency surgery. But, under certain circumstances, conservative management is feasible, avoids the need for gastrectomy, and has a low mortality rate. Postponed reconstructive surgery is usually performed several months after caustic ingestion to restore intestinal contin... περισσότερα »

Endoscopic Management of Superficial Esophageal Adenocarcinoma

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 34 δευτερόλεπτα
Emerging Concepts for the Endoscopic Management of Superficial Esophageal Adenocarcinoma: Abstract IntroductionEndoscopic therapy has revolutionized the treatment of Barrett’s esophagus with high-grade dysplasia (HGD) or intramucosal adenocarcinoma by allowing preservation of the esophagus in many patients who would previously have had an esophagectomy. This paradigm shift initially occurred at high-volume centers in North America and Europe but now is becoming mainstream therapy. There is a lack of uniform guidelines and algorithms for the management of these patients. Our aim wa... περισσότερα »

A novel BAP1 mutation is associated with melanocytic neoplasms and thyroid cancer

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 34 δευτερόλεπτα
A novel BAP1 mutation is associated with melanocytic neoplasms and thyroid cancer via http://rss.sciencedirect.com/publication/science/22107762 Publication date: Available online 22 December 2015 *Source:*Cancer Genetics Author(s): Kevin McDonnell, Gregory T. Gallanis, Kathleen A. Heller, Eleni-Marina Melas, Gregory Idos, Julie O. Culver, Sue-Ellen Martin, David H. Peng, Stephen B. Gruber Germline mutations in the tumor suppressor gene, BRCA-1 associated protein (BAP1), underlie a tumor predisposition syndrome characterized by increased risk for numerous cancers including uveal melanom... περισσότερα »

Use of dermis-fat grafts in the prevention of Frey’s syndrome after parotidectomy

Alexandros G. SfakianakisστοOroFacial Medicine by Alexandros G.SfakianakisΠριν από 34 δευτερόλεπτα
Publication date: Available online 23 December 2015 *Source:*Journal of Cranio-Maxillofacial Surgery Author(s): Sven Holger Baum, Roman Pförtner, Friederike Ladwein, Claus Schmeling, Gunnar Rieger, Christopher Mohr ObjectiveTo examine the role of dermis-fat grafts in preventing gustatory sweating and in the reconstruction of facial contour defects after parotidectomy.PatientsTwenty-three patients with tumours of the parotid gland were enrolled in this prospective clinical study from January 2006 to February 2014. All of them were evaluated for wound complications, Frey's syndrome, s...περισσότερα »

[A case of the successful function-preserving treatment of hyoid bone chondrosarcoma].

Alexandros SfakianakisστοHead and Neck Diseases by Alexandros G.SfakianakisΠριν από 34 δευτερόλεπτα
Related Articles *[A case of the successful function-preserving treatment of hyoid bone chondrosarcoma].* Vestn Otorinolaringol. 2015;80(5):91-2 Authors: Klochikhin AL, Klochikhin MA, Kuleshov BY Abstract The authors report a case of the successful function-preserving treatment of a rare neck tumour, chondrosarcoma originating from the hyoid bone. The proposed combined treatment allowed to preserve the respiratory, voice-generating and protective functions of the larynx. The dynamic follow up failed to reveal the development of relapse or metastases during 1 year after surgery. ... περισσότερα »

Thyroid cancer in a long-term nonprogressor HIV-1 infection.

Alexandros SfakianakisστοHead and Neck Diseases by Alexandros G.SfakianakisΠριν από 34 δευτερόλεπτα
*Thyroid cancer in a long-term nonprogressor HIV-1 infection.* Indian J Sex Transm Dis. 2015 Jul-Dec;36(2):195-7 Authors: Phatak UA, Chitale PV, Jagdale RV Abstract Long-term non-progressor HIV infection (LTNP-HIV) is seen in <1 percent of HIV-afflicted population. There are definite criteria for the diagnosis of LTNP-HIV. Malignancies either solid tumors or haematological cancers have not been reported in such population. We report here a rare case of follicular thyroid carcinoma in LTNP-HIV infection. She never had any opportunistic infections. She did not receive anti-retrovir... περισσότερα »

Patterns and functional implications of rare germline variants across 12 cancer types.

Alexandros SfakianakisστοHead and Neck Diseases by Alexandros G.SfakianakisΠριν από 34 δευτερόλεπτα
*Patterns and functional implications of rare germline variants across 12 cancer types.* Nat Commun. 2015;6:10086 Authors: Lu C, Xie M, Wendl MC, Wang J, McLellan MD, Leiserson MD, Huang KL, Wyczalkowski MA, Jayasinghe R, Banerjee T, Ning J, Tripathi P, Zhang Q, Niu B, Ye K, Schmidt HK, Fulton RS, McMichael JF, Batra P, Kandoth C, Bharadwaj M, Koboldt DC, Miller CA, Kanchi KL, Eldred JM, Larson DE, Welch JS, You M, Ozenberger BA, Govindan R, Walter MJ, Ellis MJ, Mardis ER, Graubert TA, Dipersio JF, Ley TJ, Wilson RK, Goodfellow PJ, Raphael BJ, Chen F, Johnson KJ, Parvin JD, Ding... περισσότερα »

Insulinoma in a patient with type 2 diabetes mellitus.

Alexandros SfakianakisστοHead and Neck Diseases by Alexandros G.SfakianakisΠριν από 34 δευτερόλεπτα
Related Articles *Insulinoma in a patient with type 2 diabetes mellitus.* Acta Med Iran. 2015;53(5):317-9 Authors: Ghafoori S, Lankarani M Abstract Insulinoma in a patient with pre-existing diabetes is extremely rare. Only a small number of cases have been reported all over the world. We report a case of insulinoma in a patient with type 2 diabetes. A 63-year-old female was diagnosed to have diabetes mellitus six years ago, she was given metformin and sulphonylurea to control her glycemia, she had adequate glycemic control for many years, but thereafter, the patient has experien... περισσότερα »

[Multiple endocrine neoplasia type 2B].

Alexandros SfakianakisστοHead and Neck Diseases by Alexandros G.SfakianakisΠριν από 34 δευτερόλεπτα
[image: http:--http://ift.tt/1PjZjdS] Related Articles *[Multiple endocrine neoplasia type 2B].* Ned Tijdschr Geneeskd. 2015;159:A7719 Authors: Pijnenburg-Kleizen KJ, van Santen HM, Koolen DA, Claahsen-van der Grinten HL Abstract BACKGROUND: Multiple endocrine neoplasia type 2b (MEN2B) is a rare syndrome characterised by the occurrence of medullary thyroid carcinoma at a young age in all patients, and phaeochromocytoma at a later age in half of the patients. Once a medullary thyroid carcinoma causes symptoms, it has usually already metastasised to the lymph nodes and curative tre... περισσότερα »

Laparoscopic Treatment of Sclerosing Stromal Tumor of the Ovary in a Woman With Gorlin-Goltz Syndrome: A Case Report and Review of the Literature.

Alexandros SfakianakisστοHead and Neck Diseases by Alexandros G.SfakianakisΠριν από 34 δευτερόλεπτα
[image: http:--linkinghub.elsevier.com-ihub-imag] Related Articles *Laparoscopic Treatment of Sclerosing Stromal Tumor of the Ovary in a Woman With Gorlin-Goltz Syndrome: A Case Report and Review of the Literature.* J Minim Invasive Gynecol. 2015 Jul-Aug;22(5):892-5 Authors: Grechi G, Clemente N, Tozzi A, Ciavattini A Abstract Gorlin-Goltz syndrome is a rare hereditary multisystemic disease. Multiple basal cell carcinomas, odontogenic keratocysts, and skeletal abnormalities are the main clinical manifestations of the syndrome, but several organs can be involved. Moreover, this con... περισσότερα »

Invasive, atypical and aggressive pituitary adenomas and carcinomas.

Alexandros SfakianakisστοHead and Neck Diseases by Alexandros G.SfakianakisΠριν από 34 δευτερόλεπτα
[image: http:--linkinghub.elsevier.com-ihub-imag] Related Articles *Invasive, atypical and aggressive pituitary adenomas and carcinomas.* Endocrinol Metab Clin North Am. 2015 Mar;44(1):99-104 Authors: Sav A, Rotondo F, Syro LV, Di Ieva A, Cusimano MD, Kovacs K Abstract Aggressive pituitary adenomas have a high risk of recurrence, a lack of therapeutic response, and resistance to conventional treatment. So far, no satisfactory biomarkers are available for predicting their behavior. Some specific pituitary adenoma histotypes are more prone to follow an aggressive behavior. Pituitary...περισσότερα »

Mixed ovarian germ cell tumor composed of immature teratoma, yolk sac tumor and embryonal carcinoma.

Alexandros SfakianakisστοHead and Neck Diseases by Alexandros G.SfakianakisΠριν από 34 δευτερόλεπτα
Related Articles *Mixed ovarian germ cell tumor composed of immature teratoma, yolk sac tumor and embryonal carcinoma.* J Coll Physicians Surg Pak. 2014 Nov;24 Suppl 3:S198-200 Authors: Wang Y, Zhou F, Qian Z, Qing J, Zhao M, Huang L Abstract We report the case of a 19-year-old woman experiencing lower abdominal distension and pain. Laboratory tests indicated elevated serum levels of Alpha-Fetoprotein (AFP) and human Chorionic Gonadotropin (hCG). A large mass was detected in the abdomen by physical examination and by transvaginal ultrasonography. Exploratory laparotomy was perfor... περισσότερα »

Comparison of the KIR3DS1/Bw4 distribution in Chinese healthy and acute myeloid leukemia individuals.

Alexandros SfakianakisστοHead and Neck Diseases by Alexandros G.SfakianakisΠριν από 34 δευτερόλεπτα
[image: http:--linkinghub.elsevier.com-ihub-imag] Related Articles *Comparison of the KIR3DS1/Bw4 distribution in Chinese healthy and acute myeloid leukemia individuals.* Hum Immunol. 2015 Mar;76(2-3):79-82 Authors: Tao S, He Y, Zhang W, Wang W, He J, Han Z, Chen N, Dong L, He J, Zhu F, Lv H Abstract Killer cell immunoglobulin like receptor (KIR) 3DS1 is one of the most important activating receptors and some studies revealed that KIR3DS1 combined with HLA ligand was not related to acute myeloid leukemia (AML), but rare data was reported in Chinese population. In this study, KIR3...περισσότερα »

Epithelioid trophoblastic tumor: an unusual malignancy of ovary.

Alexandros SfakianakisστοHead and Neck Diseases by Alexandros G.SfakianakisΠριν από 34 δευτερόλεπτα
Related Articles *Epithelioid trophoblastic tumor: an unusual malignancy of ovary.* J Coll Physicians Surg Pak. 2014 Nov;24 Suppl 3:S201-3 Authors: Mahmood H, Faheem M, Tahir M, Arif S, Mahmood S, Irfan J Abstract Epithelioid Trophoblastic Tumor (ETT) is a distinct but rare variety of gestational trophoblastic tumors. Misdiagnosis delays effective treatment and affects the survival. The case being reported here involved a 43 years old lady presented with 4 months history of intermenstrual per vaginal bleeding and 6 weeks amenorrhea. Workup has revealed pelvic mass. The patient un...περισσότερα »

Isolated rupture of teres major in a goalkeeper

Alexandros G. SfakianakisστοΟγκολογίαΠριν από 34 δευτερόλεπτα
A complete rupture of the teres major is an extremely rare injury and rarely described in the literature. We report the first case of an isolated rupture of the teres major in a professional football goalkeeper. The diagnosis requires a high degree of suspicion and complementation by image examinations. Conservative treatment has a high success rate with early return to sport. from Cases via ola Kala on Inoreader http://ift.tt/1Yx1nHd via IFTTT

Nager acrofacial dysostosis: a rare genetic disorder causing bilateral temperomandibular joint ankylosis in a 10-year-old girl

Alexandros G. SfakianakisστοΟγκολογίαΠριν από 34 δευτερόλεπτα
Description A 10-year-old girl presented to the oral medicine department, with restricted mouth opening since childhood. Her family history revealed that she was the third child born of a consanguineous marriage. She was born after an unremarkable pregnancy, with a birth weight of 2.3 kg. Physical examination revealed downslanting palpebral fissures, microretrognathia, malar hypoplasia, a sloping forehead, high nasal bridge with an upturned nasal tip and short philtrum (figure 1). She was also noted to have short forearms, proximal radioulnar synostosis (figure 2), hypoplastic th... περισσότερα »

Non-syndromic primary maxillary peg central incisors with multiple wormian bones in a 6-year-old boy: an unusual presentation

Alexandros G. SfakianakisστοΟγκολογίαΠριν από 34 δευτερόλεπτα
Description The peg-shaped conical tooth is the supernumerary tooth most commonly found in the permanent dentition. It develops with root formation ahead of or at an equivalent stage to that of the permanent incisors and usually presents as a mesiodens.1 Tooth malformations such as conical incisors and conical canines are commonly seen in hypohidrotic ectodermal dysplasia males and may also occur in heterozygous females to a less severe degree.2 Wormian bones are small bones that are often found within the sutures and fontanelles of the skull. They are often considered to be a s...περισσότερα »

Very Early Carotid Endarterectomy After Intravenous Thrombolysis

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 38 δευτερόλεπτα
Very Early Carotid Endarterectomy After Intravenous Thrombolysis via ScienceDirect Publication: European Journal of Vascular and Endovascular Surgery Publication date: Available online 19 December 2015 *Source:*European Journal of Vascular and Endovascular Surgery Author(s): C. Azzini, M. Gentile, A. De Vito, L. Traina, E. Sette, E. Fainardi, F. Mascoli, I. Casetta Objective/BackgroundThe timing of carotid endarterectomy (CEA) after thrombolysis is still a matter of debate. The aim of this study was to analyse a cohort of patients undergoing urgent endarterectomy after intravenous thro...περισσότερα »

Antiplatelet Therapy in Carotid Artery Stenting and Carotid Endarterectomy

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 38 δευτερόλεπτα
in the Asymptomatic Carotid Surgery Trial-2 via ScienceDirect Publication: European Journal of Vascular and Endovascular Surgery Publication date: Available online 21 December 2015 *Source:*European Journal of Vascular and Endovascular Surgery Author(s): A. Huibers, A. Halliday, R. Bulbulia, G. Coppi, G.J. de Borst ObjectiveStrokes are infrequent but potentially serious complications following carotid intervention, but antiplatelet therapy can reduce these risks. There are currently no specific guidelines on dose or duration of peri-procedural antiplatelet treatment for patients underg...περισσότερα »

Plaque Echolucency and the Risk of Ischaemic Stroke in Patients with Asymptomatic Carotid Stenosis

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 38 δευτερόλεπτα
Within the First Asymptomatic Carotid Surgery Trial (ACST-1) via ScienceDirect Publication: European Journal of Vascular and Endovascular Surgery Publication date: Available online 22 December 2015 *Source:*European Journal of Vascular and Endovascular Surgery Author(s): A. Huibers, G.J. de Borst, R. Bulbulia, H. Pan, A. Halliday Objective/BackgroundOn ultrasound, potentially “high risk” carotid plaques may appear echolucent. In this study, whether a confident classification of echolucent plaque was a predictor of future ipsilateral ischaemic stroke in asymptomatic patients randomized ...περισσότερα »

Insecticide on the peripheral olfactory response and sexual behavior in a pest insect

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 38 δευτερόλεπτα
Unexpected effects of sublethal doses of insecticide on the peripheral olfactory response and sexual behavior in a pest insect: AbstractPesticides have long been used as the main solution to limit agricultural pests, but their widespread use resulted in chronic or diffuse environmental pollutions, development of insect resistances, and biodiversity reduction. The effects of low residual doses of these chemical products on organisms that affect both targeted species (crop pests) but also beneficial insects became a major concern, particularly because low doses of pesticides can indu... περισσότερα »

Delayed diagnosis of anaphylaxis secondary to ondansetron: A case report

Alexandros G. SfakianakisστοAnaesthesiologyΠριν από 42 δευτερόλεπτα
No abstract available from Anaesthesia via ola Kala on Inoreader http://ift.tt/1QWTPHO via IFTTT

The transparent clinical trial: Why we need complete and informative prospective trial registration

Alexandros G. SfakianakisστοAnaesthesiologyΠριν από 42 δευτερόλεπτα
No abstract available from Anaesthesia via ola Kala on Inoreader http://ift.tt/1QWTQvd via IFTTT

Zero-heat flux thermometry

Alexandros G. SfakianakisστοAnaesthesiologyΠριν από 42 δευτερόλεπτα
No abstract available from Anaesthesia via ola Kala on Inoreader http://ift.tt/1ZoUg0k via IFTTT

Dexmedetomidine added to an opioid-based analgesic regimen for the prevention of postoperative nausea and vomiting in highly susceptible patients: A randomised controlled trial

Alexandros G. SfakianakisστοAnaesthesiologyΠριν από 42 δευτερόλεπτα
[image: image]BACKGROUND: Dexmedetomidine, an α2 adrenergic receptor agonist, has analgesic, sedative and sympatholytic properties, with a lack of respiratory depression. It is licensed only for intensive care sedation. OBJECTIVE: The objective of this study is to investigate whether intravenous (i.v.) patient-controlled analgesia (PCA) with dexmedetomidine added to a fentanyl-based drug mixture could reduce postoperative nausea and vomiting (PONV) in highly susceptible patients undergoing lumbar spinal surgery. DESIGN: A randomised, double-blinded study. SETTING: At a tertiary univ... περισσότερα »

Measuring regional cerebral oxygen saturation during surgery in the prone position

Alexandros G. SfakianakisστοAnaesthesiologyΠριν από 42 δευτερόλεπτα
[image: image]No abstract available from Anaesthesia via ola Kala on Inoreader http://ift.tt/1ZoUhBH via IFTTT

Postoperative nausea and vomiting: The role of the dopamine D2 receptor TaqIA polymorphism

Alexandros G. SfakianakisστοAnaesthesiologyΠριν από 42 δευτερόλεπτα
[image: image]BACKGROUND: The risk of developing postoperative nausea and vomiting (PONV), apart from conventional risk factors, probably includes a genetic background. OBJECTIVES: We examined the association of the DRD2 TaqIA polymorphism with PONV in a high-risk cohort of patients. DESIGN: A prospective, double-blind observational trial. SETTING: Single-centre primary care in Western Germany. PATIENTS: A total of 306 patients undergoing elective strabismus surgery under anaesthesia with etomidate/alfentanil/mivacurium (induction) and sevoflurane in air (maintenance). MAIN OUTCOME ... περισσότερα »

Preoxygenation by spontaneous breathing or noninvasive positive pressure ventilation with and without positive end-expiratory pressure

Alexandros G. SfakianakisστοAnaesthesiologyΠριν από 42 δευτερόλεπτα
No abstract available from Anaesthesia via ola Kala on Inoreader http://ift.tt/1QWTPHS via IFTTT

Aprepitant for antiemesis after laparoscopic gynaecological surgery: A randomised controlled trial

Alexandros G. SfakianakisστοAnaesthesiologyΠριν από 42 δευτερόλεπτα
[image: image]BACKGROUND: Ondansetron, a 5-HT3 receptor antagonist, and aprepitant, a neurokinin-1 receptor antagonist, block the emetic effect of serotonin and neurokinin, respectively. Aprepitant combined with ondansetron can be more effective for preventing emesis in patients at high risk of postoperative nausea and vomiting (PONV). OBJECTIVE: To investigate the prophylactic effect of combining aprepitant with ondansetron compared with ondansetron alone on PONV in patients with fentanyl-based patient-controlled analgesia (PCA) after laparoscopic gynaecological surgery. DESIGN: Si...περισσότερα »

Falsely reduced bispectral index during light anaesthesia in the elderly

Alexandros G. SfakianakisστοAnaesthesiologyΠριν από 42 δευτερόλεπτα
[image: image]No abstract available from Anaesthesia via ola Kala on Inoreader http://ift.tt/1QWTPHE via IFTTT

Alizapride and ondansetron for the prevention of postoperative nausea and vomiting in patients undergoing laparoscopic gynaecological surgery: A double-blind, randomised, placebo-controlled noninferiority study

Alexandros G. SfakianakisστοAnaesthesiologyΠριν από 42 δευτερόλεπτα
[image: image]BACKGROUND: Postoperative nausea and vomiting (PONV) can be prevented. Alizapride is an established antiemetic that may be effective in this role. OBJECTIVE: Our primary objective was to test the hypothesis that alizapride is noninferior to ondansetron for the prophylaxis of PONV. DESIGN: A randomised, placebo-controlled, double-blinded noninferiority study. SETTING: University hospitals of Leuven, Belgium, from November 2008 to July 2011. PATIENTS: A total of 523 patients undergoing laparoscopic gynaecological surgery were included in the study. Reasons for exclusion ...περισσότερα »

New anticoagulants in ambulatory anaesthesia

Alexandros G. SfakianakisστοAnaesthesiologyΠριν από 42 δευτερόλεπτα
No abstract available from Anaesthesia via ola Kala on Inoreader http://ift.tt/1ZoUjt4 via IFTTT

Evaluation of weight-adjusted doses of palonosetron for prevention of postoperative nausea and vomiting in day care laparoscopic gynaecological surgery: A dose ranging, randomised controlled trial

Alexandros G. SfakianakisστοAnaesthesiologyΠριν από 42 δευτερόλεπτα
[image: image]BACKGROUND: Palonosetron 75 mcg is being used for the prevention of postoperative nausea and vomiting. However, weight-adjusted doses in laparoscopic surgery are unevaluated. AIM: To determine the response to three doses of palonosetron (0.5, 1.0, or 1.5 mcg kg−1) over 72 h in the postoperative period in women undergoing laparoscopic gynaecological procedures. DESIGN: A randomised dose–response study. SETTING: A tertiary care hospital and research institute in north India from July to December 2014. PATIENTS: American society of Anesthesiologists physical status I and ... περισσότερα »

Mercury, lead, and cadmium in tissues

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 42 δευτερόλεπτα
Mercury, lead, and cadmium in tissues of the Caspian Pond Turtle ( Mauremys caspica ) from the southern basin of Caspian Sea: AbstractConcentrations of cadmium, lead, and mercury were measured in different tissues (liver, muscle, and shell) of 60 Caspian Pond Turtles collected from Tajan and Shiroud Rivers, southern basin of the Caspian Sea. Based on the results, different tissues showed different capacities for accumulating trace elements. The general trend of metals accumulation was: liver > shell > muscle. Results also showed that accumulation of these elements was not significa... περισσότερα »

An actuated imaging probe for generation of additional visual cues in a robotic surgery

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 42 δευτερόλεπτα
Preliminary design of an actuated imaging probe for generation of additional visual cues in a robotic surgery: Abstract BackgroundThe aim of this study was to enhance the visual feedback of surgeons, during robotic surgeries, by designing and developing an actuated 2D imaging probe, which is used in conjunction with the traditional stereoscopic camera of the da Vinci surgical system. The probe provides the surgeon with additional visual cues, overcoming visualization constraints encountered during certain scenarios of robot-assisted minimally invasive surgery. MethodsThe actuat... περισσότερα »

Monitoring bone and soft-tissue tumors after carbon-ion radiotherapy

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 42 δευτερόλεπτα
Monitoring bone and soft-tissue tumors after carbon-ion radiotherapy using 18F-FDG positron emission tomography: a retrospective cohort study: The results of treatment for malignant bone and soft-tissue tumors arising from the deep trunk and pelvis are still not acceptable due to the relatively high recurrence and low overall survival rates. Recently... Abstract Background The results of treatment for malignant bone and soft-tissue tumors arising from the deep trunk and pelvis are still not acceptable due to the relatively high recurrence and low overall survival rates. Recent... περισσότερα »

PRX1 knockdown potentiates vitamin K3 toxicity in cancer cells

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 42 δευτερόλεπτα
PRX1 knockdown potentiates vitamin K3 toxicity in cancer cells: a potential new therapeutic perspective for an old drug: Abstract BackgroundMany promising anticancer molecules are abandoned during the course from bench to bedside due to lack of clear-cut efficiency and/or severe side effects. Vitamin K3 (vitK3) is a synthetic naphthoquinone exhibiting significant in vitro and in vivo anticancer activity against multiple human cancers, and has therapeutic potential when combined with other anticancer molecules. The major mechanism for the anticancer activity of vitK3 is the generat... περισσότερα »

Milk consumption in relation to incidence of nasopharyngeal carcinoma in 48 countries/regions

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 42 δευτερόλεπτα
Milk consumption in relation to incidence of nasopharyngeal carcinoma in 48 countries/regions: Abstract BackgroundDecreasing trends of nasopharyngeal carcinoma (NPC) incidence have been consistently reported in endemic populations but the etiology of NPC remains unclear. The objective of our study was to assess the international and local (Hong Kong) correlations of milk and dairy products per capita consumption with NPC incidence. MethodsWe conducted an ecological study in 48 countries/regions. Age standardized incidence rates of NPC were obtained from the Cancer Incidence in... περισσότερα »

Cisplatin and 5-fluorouracil in a patient with esophageal cancer on peritoneal dialysis

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 42 δευτερόλεπτα
A pharmacokinetic analysis of cisplatin and 5-fluorouracil in a patient with esophageal cancer on peritoneal dialysis: Abstract BackgroundVery little is known about the pharmacokinetics of chemotherapeutic agents in patients also being treated with continuous ambulatory peritoneal dialysis. We sought to evaluate the pharmacokinetics of cisplatin and 5-fluorouracil in plasma and peritoneal dialysate in a patient being treated for esophageal adenocarcinoma. MethodsA single patient with esophageal adenocarcinoma and on peritoneal dialysis for end-stage renal disease was treated w...περισσότερα »

Expression and function of histamine and its receptors in atopic dermatitis

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 42 δευτερόλεπτα
Expression and function of histamine and its receptors in atopic dermatitis: Abstract BackgroundAtopic dermatitis constitutes a most burdensome chronic inflammatory skin disease. Standard treatment is cumbersome and often targets its main symptom, pruritus, only insufficiently. FindingsRecent advances in our understanding of the role of histamine and its four receptors suggest new approaches which target the histamine receptors alone or as combination therapies to more efficiently combat pruritus and inflammation in atopic dermatitis. ConclusionsWith this review, we provide... περισσότερα »

Paediatric tumour boards

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 42 δευτερόλεπτα
Paediatric tumour boards in Spain: a national survey: Abstract PurposeMultidisciplinary tumour boards (MDTs) are conducted worldwide for the management of patients with cancer, and they deliver a higher standard of care by simultaneously involving different specialists in diagnosis and treatment planning. However, information of paediatric MDTs functioning is scarce. A pilot study was conducted in Spain in the frame of the European Expert Paediatric Oncology Reference Network for Diagnostics and Treatment (ExPO-r-Net). MethodsA specific questionnaire was designed regarding vari... περισσότερα »

Coexistent Hashimoto’s thyroiditis on lymph node metastasis and prognosis in papillary thyroid microcarcinoma

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 42 δευτερόλεπτα
The impact of coexistent Hashimoto’s thyroiditis on lymph node metastasis and prognosis in papillary thyroid microcarcinoma: AbstractThe impact of coexistent Hashimoto’s thyroiditis (HT) on lymph node metastasis (LNM) and prognosis in papillary thyroid microcarcinoma (PTMC) remains controversial. We evaluated the association of coexistent HT with clinicopathologic parameters, LNM, and prognosis by retrospectively reviewing a series of consecutive patients treated for PTMC at Fudan University Cancer Center from January 2005 to December 2010. Of all 1,250 patients with complete data ... περισσότερα »

Anatomical study of pterygoid canal (PC) and palatovaginal canal (PVC) in endoscopic trans-sphenoidal approach.

Alexandros G. SfakianakisστοHead and NeckΠριν από 44 δευτερόλεπτα
*Anatomical study of pterygoid canal (PC) and palatovaginal canal (PVC) in endoscopic trans-sphenoidal approach.* Surg Radiol Anat. 2015 Dec 22; Authors: Cheng Y, Gao H, Song G, Li Y, Zhao G Abstract PURPOSE: The primary purpose of our work was to make anatomical measurements of pterygoid canal (PC) and palatovaginal canal (PVC). The secondary goal was to locate the two structures based on the landmarks in the trans-sphenoidal surgery and draw a safe corridor of fenestration in the bottom of sphenoid sinus during surgical procedure to sphenopalatine region. MATERIALS AND METHODS... περισσότερα »

A simple pre-operative imaging method to assess donor and recipient anatomy in hemi-hamate arthroplasty for proximal interphalangeal joint reconstruction.

Alexandros G. SfakianakisστοHead and NeckΠριν από 44 δευτερόλεπτα
*A simple pre-operative imaging method to assess donor and recipient anatomy in hemi-hamate arthroplasty for proximal interphalangeal joint reconstruction.* Surg Radiol Anat. 2015 Dec 21; Authors: Calva D, Calotta N, Lopez J, Christopher A, Magid D, Demehri S, Lifchez SD Abstract PURPOSE: Post-traumatic arthritis is common in long-term follow-up of patients undergoing hemi-hamate arthroplasty (HHA). We hypothesize that anatomic mismatch could play a role in the development of arthritis. The purpose of this study is to establish a novel, computed tomography (CT)-based imaging te... περισσότερα »

This Month in Radiology.

Alexandros G. SfakianakisστοHead and NeckΠριν από 44 δευτερόλεπτα
*This Month in Radiology.* Radiology. 2016 Jan;278(1):3A-4A Authors: PMID: 26691001 [PubMed - in process] from #PubMed 2 via ola Kala on Inoreader http://ift.tt/1Mw02E9 via IFTTT

Targeted Screening of Individuals at High Risk for Pancreatic Cancer: Results of a Simulation Model.

Alexandros G. SfakianakisστοHead and NeckΠριν από 44 δευτερόλεπτα
*Targeted Screening of Individuals at High Risk for Pancreatic Cancer: Results of a Simulation Model.* Radiology. 2016 Jan;278(1):306 Authors: Pandharipande PV, Heberle C, Dowling EC, Kong CY, Tramontano A, Perzan KE, Brugge W, Hur C PMID: 26691000 [PubMed - in process] from #PubMed 2 via ola Kala on Inoreader http://ift.tt/1QHuPWN via IFTTT

Intravenous Contrast Material-induced Nephropathy: Causal or Coincident Phenomenon?

Alexandros G. SfakianakisστοHead and NeckΠριν από 44 δευτερόλεπτα
*Intravenous Contrast Material-induced Nephropathy: Causal or Coincident Phenomenon?* Radiology. 2016 Jan;278(1):306 Authors: McDonald RJ, McDonald JS, Bida JP, Carter RE, Fleming CJ, Misra S, Williamson EE, Kallmes DF PMID: 26690999 [PubMed - in process] from #PubMed 2 via ola Kala on Inoreader http://ift.tt/1Mw052Z via IFTTT

Are Noninvasive Methods Clinically Useful in Advanced, Decompensated Liver Cirrhosis When "Les Jeux Sont Faits"?

Alexandros G. SfakianakisστοHead and NeckΠριν από 44 δευτερόλεπτα
*Are Noninvasive Methods Clinically Useful in Advanced, Decompensated Liver Cirrhosis When "Les Jeux Sont Faits"?* Radiology. 2016 Jan;278(1):304-6 Authors: Colecchia A, Marasco G, Festi D PMID: 26690998 [PubMed - in process] from #PubMed 2 via ola Kala on Inoreader http://ift.tt/1QHuPWJ via IFTTT

Consensus on Elastography of the Liver.

Alexandros G. SfakianakisστοHead and NeckΠριν από 44 δευτερόλεπτα
*Consensus on Elastography of the Liver.* Radiology. 2016 Jan;278(1):303-4 Authors: Trout AT, Podberesky DJ, Dillman JR PMID: 26690997 [PubMed - in process] from #PubMed 2 via ola Kala on Inoreader http://ift.tt/1Mw052M via IFTTT

Shared Decision Making in Interventional Radiology.

Alexandros G. SfakianakisστοHead and NeckΠριν από 44 δευτερόλεπτα
*Shared Decision Making in Interventional Radiology.* Radiology. 2016 Jan;278(1):302-3 Authors: Birkeland S PMID: 26690996 [PubMed - in process] from #PubMed 2 via ola Kala on Inoreader http://ift.tt/1Mw04My via IFTTT

Case 225: Leiomyoma.

Alexandros G. SfakianakisστοHead and NeckΠριν από 44 δευτερόλεπτα
*Case 225: Leiomyoma.* Radiology. 2016 Jan;278(1):297-301 Authors: DiPoce J, Liu-Jarin X, Newhouse J Abstract History A 33-year-old pregnant woman (gravida 11, para 8) presented with increasing severe abdominal pain during the first trimester of pregnancy and increasing abdominal distention out of proportion to her prior pregnancies. Ultrasonography (US) without Doppler performed at another hospital had revealed a pelvic mass; therefore, this patient had been referred to our institution for further evaluation. Unenhanced magnetic resonance (MR) imaging was then performed at 8 we... περισσότερα »

Case 229.

Alexandros G. SfakianakisστοHead and NeckΠριν από 44 δευτερόλεπτα
*Case 229.* Radiology. 2016 Jan;278(1):295-6 Authors: Davis DL, Resnik CS PMID: 26690994 [PubMed - in process] from #PubMed 2 via ola Kala on Inoreader http://ift.tt/1Mw027b via IFTTT

Imaging and Pathology of Pancreatic Neoplasms: A Pictorial Atlas Edited by Mirko D'Onofrio , Paola Capelli , and Paolo Pederzoli New York, NY , Springer Science & Business Media , 2015 . ISBN: 978-88-470-5677-0 . Hardcover, $109.00; pp 432 .

Alexandros G. SfakianakisστοHead and NeckΠριν από 44 δευτερόλεπτα
*Imaging and Pathology of Pancreatic Neoplasms: A Pictorial Atlas Edited by Mirko D'Onofrio , Paola Capelli , and Paolo Pederzoli New York, NY , Springer Science & Business Media , 2015 . ISBN: 978-88-470-5677-0 . Hardcover, $109.00; pp 432 .* Radiology. 2016 Jan;278(1):52-3 Authors: PMID: 26690993 [PubMed - in process] from #PubMed 2 via ola Kala on Inoreader http://ift.tt/1MvZZbF via IFTTT

Bone Marrow MRI: A Pattern-Based Approach Lia Angela Moulopoulos and Vassilis Koutoulidis New York, NY : Springer Science & Business Media , 2015 . ISBN: 978-88-470-5315-1 . Hardcover, $159.00; pp 172 .

Alexandros G. SfakianakisστοHead and NeckΠριν από 44 δευτερόλεπτα
*Bone Marrow MRI: A Pattern-Based Approach Lia Angela Moulopoulos and Vassilis Koutoulidis New York, NY : Springer Science & Business Media , 2015 . ISBN: 978-88-470-5315-1 . Hardcover, $159.00; pp 172 .* Radiology. 2016 Jan;278(1):52 Authors: PMID: 26690992 [PubMed - in process] from #PubMed 2 via ola Kala on Inoreader http://ift.tt/1QHuQtV via IFTTT

Pitfalls in Liver Imaging.

Alexandros G. SfakianakisστοHead and NeckΠριν από 44 δευτερόλεπτα
*Pitfalls in Liver Imaging.* Radiology. 2016 Jan;278(1):34-51 Authors: Vilgrain V, Lagadec M, Ronot M Abstract Despite various sophisticated imaging techniques, there are numerous pitfalls in liver imaging. This review for residents discusses the major traps in image interpretation and gives some diagnostic clues to confidently interpret computed tomographic or magnetic resonance imaging studies. (©) RSNA, 2016 Online supplemental material is available for this article. PMID: 26690991 [PubMed - in process] from #PubMed 2 via ola Kala on Inoreader http://ift.tt/1Mw01QG via IFTTT

Clinical Intravoxel Incoherent Motion and Diffusion MR Imaging: Past, Present, and Future.

Alexandros G. SfakianakisστοHead and NeckΠριν από 44 δευτερόλεπτα
*Clinical Intravoxel Incoherent Motion and Diffusion MR Imaging: Past, Present, and Future.* Radiology. 2016 Jan;278(1):13-32 Authors: Iima M, Le Bihan D Abstract The concept of diffusion magnetic resonance (MR) imaging emerged in the mid-1980s, together with the first images of water diffusion in the human brain, as a way to probe tissue structure at a microscopic scale, although the images were acquired at a millimetric scale. Since then, diffusion MR imaging has become a pillar of modern clinical imaging. Diffusion MR imaging has mainly been used to investigate neurologic dis... περισσότερα »

Do Radiologists Have Stage Fright? Tumor Staging and How We Can Add Value to the Care of Patients with Cancer.

Alexandros G. SfakianakisστοHead and NeckΠριν από 44 δευτερόλεπτα
*Do Radiologists Have Stage Fright? Tumor Staging and How We Can Add Value to the Care of Patients with Cancer.* Radiology. 2016 Jan;278(1):11-2 Authors: Glastonbury CM, Bhosale PR, Choyke PL, D'Orsi CJ, Erasmus JJ, Gill RR, Mukherji SK, Panicek DM, Schwartz LH, Subramaniam RM, Sullivan DC PMID: 26690989 [PubMed - in process] from #PubMed 2 via ola Kala on Inoreader http://ift.tt/1QHuPpF via IFTTT

Radiology 2016: The Care and Scientific Rigor Used to Process and Evaluate Original Research Manuscripts for Publication.

Alexandros G. SfakianakisστοHead and NeckΠριν από 44 δευτερόλεπτα
*Radiology 2016: The Care and Scientific Rigor Used to Process and Evaluate Original Research Manuscripts for Publication.* Radiology. 2016 Jan;278(1):6-10 Authors: Levine D, Kressel HY PMID: 26690988 [PubMed - in process] from #PubMed 2 via ola Kala on Inoreader http://ift.tt/1QHuNy8 via IFTTT

Richard L. Baron, MD, President, Radiological Society of North America, 2016.

Alexandros G. SfakianakisστοHead and NeckΠριν από 44 δευτερόλεπτα
*Richard L. Baron, MD, President, Radiological Society of North America, 2016.* Radiology. 2016 Jan;278(1):4-5 Authors: Tublin M PMID: 26690987 [PubMed - in process] from #PubMed 2 via ola Kala on Inoreader http://ift.tt/1MvZYEp via IFTTT

Editor's Recognition Awards.

Alexandros G. SfakianakisστοHead and NeckΠριν από 44 δευτερόλεπτα
*Editor's Recognition Awards.* Radiology. 2016 Jan;278(1):2-3 Authors: Kressel HY PMID: 26690986 [PubMed - in process] from #PubMed 2 via ola Kala on Inoreader http://ift.tt/1kgPJNK via IFTTT

Anti-epidermal growth factor receptor skin toxicity: a matter of topical hydration

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 51 δευτερόλεπτα
Anti-epidermal growth factor receptor skin toxicity: a matter of topical hydration: [image: image]Skin toxicity is a frequent complication of anti-epidermal growth factor receptor therapy, which can be an obstacle in maintaining the dose intensity and may negatively impact on the clinical outcome of cancer patients. Skin lesions depend on the disruption of the keratinocyte development pathways and no treatment is clearly effective in resolving the cutaneous alterations frequently found during anti-epidermal growth factor receptor therapy. Among systemic treatments, oral tetracycline... περισσότερα »

A metronomic schedule as salvage chemotherapy for upper gastrointestinal tract cancer

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 51 δευτερόλεπτα
A metronomic schedule as salvage chemotherapy for upper gastrointestinal tract cancer: [image: image] In recent years, metronomic chemotherapy, consisting of continuous administration of low doses of cytotoxic agents, has being used as rescue therapy for different tumours. The aim of this study was to retrospectively assess the efficacy and safety of low-dose metronomic, oral capecitabine in pretreated or frail patients with recurrent upper gastrointestinal tract cancer. Patients with pretreated upper gastrointestinal tract cancer or who were not candidates for standard chemotherap... περισσότερα »

Dihydroartemisinin suppresses growth of squamous cell carcinoma A431 cells by targeting the Wnt/β-catenin pathway

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 51 δευτερόλεπτα
Dihydroartemisinin suppresses growth of squamous cell carcinoma A431 cells by targeting the Wnt/β-catenin pathway: [image: image]The antimalarial effects of dihydroartemisinin (DHA) have been well documented. However, its potential against skin cancer has not been explored as yet. Therefore, we assessed the function of DHA as an inhibitory factor of squamous cell carcinoma in A431 cells and the underlying mechanism was explored. After stimulation of A431 cells and Hacat cells (normal human keratinocyte cells, as control) with various doses of DHA, the 3-(4,5-dimethyl-2-thiazolyl)-2,...περισσότερα »

How do musical tonality and experience affect visual working memory?

Alexandros G. SfakianakisστοΝευρολογία κ' ΝευροχειρουργικήΠριν από 54 δευτερόλεπτα
[image: image]The influence of music on the human brain has continued to attract increasing attention from neuroscientists and musicologists. Currently, tonal music is widely present in people's daily lives; however, atonal music has gradually become an important part of modern music. In this study, we conducted two experiments: the first one tested for differences in perception of distractibility between tonal music and atonal music. The second experiment tested how tonal music and atonal music affect visual working memory by comparing musicians and nonmusicians who were placed in ... περισσότερα »

Effect of controlled release of brain-derived neurotrophic factor and neurotrophin-3 from collagen gel on neural stem cells

Alexandros G. SfakianakisστοΝευρολογία κ' ΝευροχειρουργικήΠριν από 54 δευτερόλεπτα
[image: image]This study aimed to examine the effect of controlled release of brain-derived neurotrophic factor (BDNF) and neurotrophin-3 (NT-3) from collagen gel on rat neural stem cells (NSCs). With three groups of collagen gel, BDNF/collagen gel, and NT-3/collagen gel as controls, BDNF and NT-3 were tested in the BDNF-NT-3/collagen gel group at different time points. The enzyme-linked immunosorbent assay results showed that BDNF and NT-3 were steadily released from collagen gels for 10 days. The cell viability test and the bromodeoxyuridine incorporation assay showed that BDNF-NT...περισσότερα »

The time course of lexical competition during spoken word recognition in Mandarin Chinese: an event-related potential study

Alexandros G. SfakianakisστοΝευρολογία κ' ΝευροχειρουργικήΠριν από 54 δευτερόλεπτα
[image: image]The present study investigated the effect of lexical competition on the time course of spoken word recognition in Mandarin Chinese using a unimodal auditory priming paradigm. Two kinds of competitive environments were designed. In one session (session 1), only the unrelated and the identical primes were presented before the target words. In the other session (session 2), besides the two conditions in session 1, the target words were also preceded by the cohort primes that have the same initial syllables as the targets. Behavioral results showed an inhibitory effect of ... περισσότερα »

Decreased voltage-gated potassium currents in rat dorsal root ganglion neurons after chronic constriction injury

Alexandros G. SfakianakisστοΝευρολογία κ' ΝευροχειρουργικήΠριν από 54 δευτερόλεπτα
[image: image]Voltage-gated potassium channels (KV) regulate pain transmission by controlling neuronal excitability. Changes in KV expression patterns may thus contribute toward hyperalgesia following nerve injury. The aim of this study was to characterize KV current density in dorsal root ganglion (DRG) neurons following chronic constriction injury (CCI) of the right sciatic nerve, a robust model of post-traumatic neuropathic pain. The study examined changes in small-diameter potassium ion currents ( from Neurology via xlomafota13 on Inoreader http://ift.tt/1Zp0BsH via IFTTT

Glutamate metabolism of astrocytes during hyperbaric oxygen exposure and its effects on central nervous system oxygen toxicity

Alexandros G. SfakianakisστοΝευρολογία κ' ΝευροχειρουργικήΠριν από 54 δευτερόλεπτα
[image: image]Hyperbaric oxygen (HBO) has been used widely in many underwater missions and clinical work. However, exposure to extremely high oxygen pressure may cause central nervous system oxygen toxicity (CNS-OT). The regulation of astrocyte glutamate metabolism is closely related to epilepsy. This study aimed to observe the effects of HBO exposure on glutamate metabolism in astrocytes and confirm the role of glutamate metabolism in CNS-OT. Anesthetized rats were exposed to 5 atmosphere absolute HBO for 80 min and microdialysis samples of brain interstitial fluid were continuousl...περισσότερα »

Quantifying movement intentions with multimodal neuroimaging for functional electrical stimulation-based rehabilitation

Alexandros G. SfakianakisστοΝευρολογία κ' ΝευροχειρουργικήΠριν από 54 δευτερόλεπτα
[image: image]Functional electrical stimulation (FES) is a common rehabilitation method for the purpose of recovery of paralyzed muscle by means of sequential electrical stimulation. Reports indicate that active participation by the patient, as opposed to simple stimulation, leads to improved recovery when using FES and other rehabilitation techniques. In this paper, we investigate the neurophysiological effect of an active participant's intention in the FES rehabilitation task. To observe the difference in brain signal between intentional and involuntary movement during FES, electr... περισσότερα »

Stimulus-preceding negativity represents a conservative response tendency

Alexandros G. SfakianakisστοΝευρολογία κ' ΝευροχειρουργικήΠριν από 54 δευτερόλεπτα
[image: image]Humans tend to be conservative and typically will retain their initial decision even if an option to change is provided. We investigated whether the stimulus-preceding negativity (SPN), an event-related potential associated with the affective-motivational anticipation of feedback in gambling tasks, represents the strong response tendency to retain an initial decision. We compared SPNs in three different card-gambling tasks wherein the participants were given the opportunity to change their initial decision after they chose one of three cards. In two of these tasks, the... περισσότερα »

Impaired cognitive reappraisal in panic disorder revealed by the late positive potential

Alexandros G. SfakianakisστοΝευρολογία κ' ΝευροχειρουργικήΠριν από 54 δευτερόλεπτα
[image: image]According to the cognitive model of panic disorder (PD), panic attacks are triggered and maintained by catastrophic misappraisals of bodily sensations. Clinically, PD is associated with impaired cognitive emotion regulation strategies involving cognitive reappraisal. To investigate the neural correlates and time course of cognitive reappraisal in patients with PD, event-related potentials were recorded from patients with PD and demographically matched control group during passive viewing of affective images under three conditions: (a) neutral pictures preceded by neutr... περισσότερα »

The neural basis of desire reasoning for self and others: an event-related potential study

Alexandros G. SfakianakisστοΝευρολογία κ' ΝευροχειρουργικήΠριν από 54 δευτερόλεπτα
[image: image]Theory of mind refers to the ability to attribute mental states to self and others, and predict actions in terms of mental states. It is still unclear how certain kinds of processing occur in theory of mind operation. The present study compared neural activities elicited by desire reasoning for self and for others under consistent or inconsistent conditions using the event-related potential method. The results showed that the late positive component (LPC) associated with desire reasoning was larger during the 450–550 ms time period in the condition of reasoning for sel... περισσότερα »

The neural basis of desire reasoning for self and others: an event-related potential study

Theory of mind refers to the ability to attribute mental states to self and others, and predict actions in terms of mental states. It is still unclear how certain kinds of processing occur in theory of mind operation. The present study compared neural activities elicited by desire reasoning for self and for others under consistent […]

Suppression of lactate dehydrogenase A compromises tumor progression by downregulation of the Warburg effect in glioblastoma

Reprogrammed glucose metabolism is an emerging hallmark of cancer cells, which show a unique metabolic phenotype known as the Warburg effect. Lactate dehydrogenase A (LDHA), a key enzyme in the glycolytic process, executes the final step by conversion of lactate into pyruvate. However, little is known about the roles of LDHA in human glioblastoma (GBM). […]

Evolution and Genetics in Medicine

Credit: Professor Brian Spratt CBE FMedSci FRS Every year, a special feature is published in Proceedings B to highlight an important and emerging field. This year is of particular importance, as 2015 marked the 350th anniversary of publishing at the Royal Society, and the anniversary of our oldest journal Philosophical Transactions. As part of our […]

Evaluation of nutritional status and support in children with congenital heart disease

Evaluation of nutritional status and support in children with congenital heart disease European Journal of Clinical Nutrition advance online publication, December 23 2015. doi:10.1038/ejcn.2015.209 Authors: A Blasquez, H Clouzeau, M Fayon, J-B Mouton, J-B Thambo, R Enaud & T Lamireau from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/22pT2o8 via IFTTT from #Med Blogs by Alexandros G.Sfakianakis […]

Identification of autoantibodies to glial fibrillary acidic protein in spinal cord injury patients

Traumatic spinal cord injury (SCI) is a devastating injury causing significant morbidity and mortality. Experimental studies have demonstrated that SCI induced cellular damage and disruption of the blood–spinal cord barrier can initiate an autoimmune response. This response is thought to be pathogenic and contribute to poor outcome. The objective of this research was to investigate […]

Enhanced phase-sensitive SSFP reconstruction for fat-water separation in phased-array acquisitions

Purpose To propose and assess a method to improve the reliability of phase-sensitive fat–water separation for phased-array balanced steady-state free precession (bSSFP) acquisitions. Phase-sensitive steady-state free precession (PS-SSFP) is an efficient fat–water separation technique that detects the phase difference between neighboring bands in the bSSFP magnetization profile. However, large spatial variations in the sensitivity profiles […]

Assessing global and regional iron content in deep gray matter as a function of age using susceptibility mapping

Purpose To investigate the correlation of non-heme iron content in deep gray matter nuclei as a function of age using quantitative susceptibility mapping (QSM) from both whole-structural and regional perspectives. Materials and Methods We studied a group of 174 normal subjects ranging from 20 to 69 years old and measured the magnetic susceptibility of seven […]

Klinisches Erscheinungsbild und Diagnose der Zöliakie

Atypische Verläufe nicht selten Das klinische Bild der Zöliakie hat sich in den letzten Jahrzehnten geändert. Die klassische Zöliakie stellt nur noch die Spitze des Eisbergs dar. Atypische Verläufe sind heute die Regel. Eine korrekte initiale Diagnosestellung ist für den weiteren Verlauf und die Therapie essenziell. from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1IpZGUJ via IFTTT

Crop niche modeling projects major shifts in common bean growing areas

Publication date: 15 March 2016 Source:Agricultural and Forest Meteorology, Volumes 218–219 Author(s): Nadiezhda Yakovleva Zitz Ramirez-Cabral, Lalit Kumar, Subhashni Taylor Crops experience different climate stresses during development. The magnitude of damage will depend on the phenological stage of the crop and the stress duration. Climate change could intensify some or all of these stresses, thus […]

Grazing effect on growing season ecosystem respiration and its temperature sensitivity in alpine grasslands along a large altitudinal gradient on the central Tibetan Plateau

Publication date: 15 March 2016 Source:Agricultural and Forest Meteorology, Volumes 218–219 Author(s): Jingxue Zhao, Tianxiang Luo, Ruicheng Li, Xiang Li, Lihua Tian Little is known about how livestock grazing could modify altitudinal trends in seasonal ecosystem respiration (Re) and its temperature sensitivity (Q10). We aim to test the hypotheses that the altitudinal grazing effect on […]

Radiation-induced undifferentiated pleomorphic sarcoma

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 57 δευτερόλεπτα
after radiation therapy for a desmoid tumour via Cancer/Radiothérapie Publication date: Available online 22 December 2015 *Source:*Cancer/Radiothérapie Author(s): J. Di Marco, R. Kaci, P. Orcel, R. Nizard, J.-D. Laredo Radiation-induced sarcoma is a long-term complication of radiation therapy. The most common secondary neoplasia is the undifferentiated pleomorphic sarcoma, which is usually described in the deep soft tissue of the trunk or extremities. Radiation-induced sarcomas have a poor prognosis. An early diagnosis and management are needed to improve the survival rate of such pat...περισσότερα »

CME: General Practice Highlights and Advances

Alexandros G. SfakianakisστοΝοσολογίαΠριν από 1 ώρα
[image: DG ME] General Practice Highlights in Depression Credit: 1.25 CME Psych Evidence-based Consults Publication Leslie Citrome, MD, MPH Vindico Advances in General Practice Medical Education and Presentations Credit: 1.00 CME Massachusetts Medical Society Acid–Base Problems in Diabetic Ketoacidosis Credit: 1.25 CME Vindico Psych Evidence-based Consults Publication Leslie Citrome, MD, MPH Credit: 1.00 CME Nemours Treating Childhood Anxiety: All you need to know but were “AFRAID” to Ask Amanda Lochrie, PhD, ABPP [image... περισσότερα »

European Journal of Epidemiology, Vol. 30, Issue 11 - New Issue Alert

Alexandros G. SfakianakisστοOnline Medical Journals by Alexandros G.SfakianakisΠριν από 1 ώρα
If this email is not displayed correctly, please click here to read this table of contents online. New Issue Alert 12/23/2015 Dear Alexandros Sfakianakis, We are pleased to deliver your requested table of contents alert for *European Journal of Epidemiology*. Volume 30 Number 11 is now available online. Important news Papers, the reference manager, for iPhone and iPad now totally free Full functionality, no in-app purchases or small print. Find, organize, read and share the research materials you care about, anytime, anywhere. Download today: http://papersapp.com/ios. » Learn m... περισσότερα »

Read Highly Accessed Articles from Genome Biology

Alexandros G. SfakianakisστοOnline Medical Journals by Alexandros G.SfakianakisΠριν από 1 ώρα
[image: BioMed eEntral] *Genome Biology* Impact Factor:10.8 Dear Dr Sfakianakis, Below is a selection of the latest, highly accessed articles from the open access journal, *Genome Biology*. [image: -] Real-time digital pathogen surveillance - the time is now [image: -] BioWardrobe: an integrated platform for analysis of epigenomics and transcriptomics data [image: -] Kiwi genome provides insights into evolution of a nocturnal lifestyle Interested in publishing with BioMed Central? Here are just a few of the initiatives we have recently implemented to make the process easier and ... περισσότερα »

Read Highly Accessed Articles from BMC Anesthesiology

Alexandros G. SfakianakisστοOnline Journals of Otolaryngology Head and Neck Surgery by Alexandros G.SfakianakisΠριν από 1 ώρα
[image: BioMed eEntral] *BMC Anesthesiology* Impact Factor:1.38 Dear Dr Sfakianakis, Below is a selection of the latest, highly accessed articles from the open access journal, *BMC Anesthesiology*. [image: -] Obesity - a risk factor for postoperative complications in general surgery? [image: -] Effects of ketamine, s-ketamine, and MK 801 on proliferation, apoptosis, and necrosis in pancreatic cancer cells [image: -] Patient-ventilator synchrony in Neurally Adjusted Ventilatory Assist (NAVA) and Pressure Support Ventilation (PSV): a prospective observational study Interested in pu... περισσότερα »

Radiation-induced undifferentiated pleomorphic sarcoma after radiation therapy for a desmoid tumour

Publication date: Available online 22 December 2015 Source:Cancer/Radiothérapie Author(s): J. Di Marco, R. Kaci, P. Orcel, R. Nizard, J.-D. Laredo Radiation-induced sarcoma is a long-term complication of radiation therapy. The most common secondary neoplasia is the undifferentiated pleomorphic sarcoma, which is usually described in the deep soft tissue of the trunk or extremities. Radiation-induced sarcomas […]

The impact of drought on ozone dry deposition over eastern Texas

Publication date: February 2016 Source:Atmospheric Environment, Volume 127 Author(s): Ling Huang, Elena C. McDonald-Buller, Gary McGaughey, Yosuke Kimura, David T. Allen Dry deposition represents a critical pathway through which ground-level ozone is removed from the atmosphere. Understanding the effects of drought on ozone dry deposition is essential for air quality modeling and management in regions […]

Patients’ strategies for eating after gastric bypass surgery: a qualitative study

Patients’ strategies for eating after gastric bypass surgery: a qualitative study European Journal of Clinical Nutrition advance online publication, December 23 2015. doi:10.1038/ejcn.2015.212 Authors: L Hillersdal, B J Christensen & L Holm from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1kgMsOA via IFTTT

Impact of weekly iron folic acid supplementation with and without vitamin B12 on anaemic adolescent girls: a randomised clinical trial

Impact of weekly iron folic acid supplementation with and without vitamin B12 on anaemic adolescent girls: a randomised clinical trial European Journal of Clinical Nutrition advance online publication, December 23 2015. doi:10.1038/ejcn.2015.215 Authors: P G Bansal, G S Toteja, N Bhatia, N K Vikram & A Siddhu from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1Sba0lC via […]

Empty plates and larger waists: a cross-sectional study of factors associated with plate clearing habits and body weight

Empty plates and larger waists: a cross-sectional study of factors associated with plate clearing habits and body weight European Journal of Clinical Nutrition advance online publication, December 23 2015. doi:10.1038/ejcn.2015.218 Authors: E Robinson & C A Hardman from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1Sb9Yu9 via IFTTT

Evaluation of nutritional status and support in children with congenital heart disease

Evaluation of nutritional status and support in children with congenital heart disease European Journal of Clinical Nutrition advance online publication, December 23 2015. doi:10.1038/ejcn.2015.209 Authors: A Blasquez, H Clouzeau, M Fayon, J-B Mouton, J-B Thambo, R Enaud & T Lamireau from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/22pT2o8 via IFTTT

Evolution and Genetics in Medicine

Credit: Professor Brian Spratt CBE FMedSci FRS Every year, a special feature is published in Proceedings B to highlight an important and emerging field. This year is of particular importance, as 2015 marked the 350th anniversary of publishing at the Royal Society, and the anniversary of our oldest journal Philosophical Transactions. As part of our […]

Use of dermis-fat grafts in the prevention of Frey’s syndrome after parotidectomy

Publication date: Available online 23 December 2015 Source:Journal of Cranio-Maxillofacial Surgery Author(s): Sven Holger Baum, Roman Pförtner, Friederike Ladwein, Claus Schmeling, Gunnar Rieger, Christopher Mohr ObjectiveTo examine the role of dermis-fat grafts in preventing gustatory sweating and in the reconstruction of facial contour defects after parotidectomy.PatientsTwenty-three patients with tumours of the parotid gland were enrolled […]

Early loading of titanium dental implants with an intra-operatively conditioned hydrophilic implant surface after 21 days of healing

Abstract Objectives The aim of the present observational medical device performance study was to test whether implants with an intra-operatively conditioned hydrophilic surface can be safely reconstructed when applying an early loading protocol after 21 days in partially edentulous posterior mandibles. Material and methods Partially edentulous patients with missing teeth in the posterior mandible were […]

Evaluation of gamma ray-induced gastrointestinal tract morphological and proliferative activity changes in rhesus monkeys

To provide support for future pharmacology and preclinical studies, we have established a stable nonhuman primate animal model to demonstrate the histopathological changes in the gastrointestinal tract following gamma ray irradiation. In this study, 12 healthy rhesus monkeys were divided into 2 groups (control and radiation groups). Animals in the radiation group were exposed to […]

Corrigendum.

Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
*Corrigendum.* Future Oncol. 2016 Jan;12(1):138 Authors: PMID: 26689965 [PubMed - in process] from #PubMed 3 via ola Kala on Inoreader http://ift.tt/1Zp2KVv via IFTTT

Corrigendum.

Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
*Corrigendum.* Future Oncol. 2015 Dec 21; Authors: PMID: 26689838 [PubMed - as supplied by publisher] from #PubMed 3 via ola Kala on Inoreader http://ift.tt/1NCd5YK via IFTTT

Female fertility preserving practices at a pediatric unit: a challenge of multiprofessional and multidisciplinary cooperation.

Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
*Female fertility preserving practices at a pediatric unit: a challenge of multiprofessional and multidisciplinary cooperation.* Tumori. 2015 Dec 17;0(0):0 Authors: Terenziani M, Meazza C, Massimino M, Viganò P, Gandola L, Mangili G, Raspagliesi F, Biasoni D, Podda M, Veneroni L, Filippi F, Riccipetitoni G, Somigliana E Abstract INTRODUCTION: Being able to have children could have an important positive effect on the future lives of pediatric cancer survivors. Working at a cancer institute makes us responsible for filling the gaps in our knowledge in this area of patient care. ME... περισσότερα »

Prognostic factors for clinical outcomes in patients with metastatic castration resistant prostate cancer treated with sequential novel androgen receptor-directed therapies.

Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
*Prognostic factors for clinical outcomes in patients with metastatic castration resistant prostate cancer treated with sequential novel androgen receptor-directed therapies.* Prostate. 2015 Dec 22; Authors: Nadal R, Tsai HL, Sinibaldi VJ, Paller CJ, Antonarakis ES, Denmeade SR, Carducci MA, Eisenberger MA Abstract BACKGROUND: Prognostic factors associated with clinical outcomes in patients with metastatic castration-resistant prostate cancer (mCRPC) treated with a novel androgen receptor-directed therapies (ARDT) in the second line setting has not been formally evaluated. PATIE...περισσότερα »

Pelvic lymph node dissection in prostate cancer: indications, extent and tailored approaches.

Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
*Pelvic lymph node dissection in prostate cancer: indications, extent and tailored approaches.* Urologia. 2015 Dec 16;0(0):0 Authors: Bianchi L, Gandaglia G, Fossati N, Suardi N, Moschini M, Cucchiara V, Bianchi M, Damiano R, Schiavina R, Shariat SF, Montorsi F, Briganti A Abstract PURPOSE: The purpose of this study is to review the current literature concerning the indication of pelvic lymph node dissection (PLND), its extent and complications in prostate cancer (PCa) staging, the available tools, and the future perspectives to assess the risk of lymph node invasion (LNI). METH...περισσότερα »

Childhood cancer survivors: considerations for surgeons in the transition from pediatric to adult care.

Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
[image: http:--linkinghub.elsevier.com-ihub-imag] Related Articles *Childhood cancer survivors: considerations for surgeons in the transition from pediatric to adult care.* Semin Pediatr Surg. 2015 Apr;24(2):93-9 Authors: Henderson TO, Nathan PC Abstract There are over 380,000 childhood cancer survivors (CCS) alive in the US, and the population is growing. CCS face significant long-term morbidity and mortality as a consequence of their cancer treatment and thus require lifelong, risk-based health care focused on surveillance and early intervention to minimize the impact of late e... περισσότερα »

Accelerated hyperfractionated intensity-modulated radiotherapy for recurrent/unresectable rectal cancer in patients with previous pelvic irradiation: results of a phase II study.

Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
[image: http:--http://ift.tt/1NMOrDk] [image: http:--http://ift.tt/1Fkw4zC] Related Articles *Accelerated hyperfractionated intensity-modulated radiotherapy for recurrent/unresectable rectal cancer in patients with previous pelvic irradiation: results of a phase II study.* Radiat Oncol. 2014;9:278 Authors: Cai G, Zhu J, Hu W, Zhang Z Abstract BACKGROUND: This study was conducted to investigate the local effects and toxicity of accelerated hyperfractionated intensity-modulated radiotherapy for recurrent/unresectable rectal cancer in patients with previous pelvic irradiation. METH... περισσότερα »

Proctitis following stereotactic body radiation therapy for prostate cancer.

Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
[image: http:--http://ift.tt/1NMOrDk] [image: http:--http://ift.tt/1Fkw4zC] Related Articles *Proctitis following stereotactic body radiation therapy for prostate cancer.* Radiat Oncol. 2014;9:277 Authors: Joh DY, Chen LN, Porter G, Bhagat A, Sood S, Kim JS, Moures R, Yung T, Lei S, Collins BT, Ju AW, Suy S, Carroll J, Lynch JH, Dritschilo A, Collins SP Abstract BACKGROUND: Proctitis after radiation therapy for prostate cancer remains an ongoing clinical challenge and critical quality of life issue. SBRT could minimize rectal toxicity by reducing the volume of rectum receiving ... περισσότερα »

Nasopharyngeal carcinoma in children and adolescents - a single institution experience of 158 patients.

Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
[image: http:--http://ift.tt/1NMOrDk] [image: http:--http://ift.tt/1Fkw4zC] Related Articles *Nasopharyngeal carcinoma in children and adolescents - a single institution experience of 158 patients.* Radiat Oncol. 2014;9:274 Authors: Liu W, Tang Y, Gao L, Huang X, Luo J, Zhang S, Wang K, Qu Y, Xiao J, Xu G, Yi J Abstract BACKGROUND: To evaluate the clinical features, treatment results, prognostic factors and late toxicities of nasopharyngeal carcinoma in children and adolescents. METHODS: Between January 1990 and January 2011, 158 NPC patients younger than 20 years old were treat...περισσότερα »

Robot assisted radical prostatectomy: the new standard?

Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
Related Articles *Robot assisted radical prostatectomy: the new standard?* Minerva Urol Nefrol. 2015 Mar;67(1):47-53 Authors: Laviana AA, Williams SB, King ED, Chuang RJ, Hu JC Abstract Over the past decade, the robotic assisted radical prostatectomy (RARP) has grown increasingly popular and quickly equated itself as the most commonly used modality to treat locally-confined prostate cancer. Despite increased utilization, there is limited comparative research demonstrating superiority for RARP over the conventional radical retropubic prostatectomy (RRP). Furthermore, though periop...περισσότερα »

Identifying amyloid pathology-related cerebrospinal fluid biomarkers for Alzheimer's disease in a multicohort study.

Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
*Identifying amyloid pathology-related cerebrospinal fluid biomarkers for Alzheimer's disease in a multicohort study.* Alzheimers Dement (Amst). 2015 Sep 1;1(3):339-348 Authors: Leung YY, Toledo JB, Nefedov A, Polikar R, Raghavan N, Xie SX, Farnum M, Schultz T, Baek Y, Deerlin VV, Hu WT, Holtzman DM, Fagan AM, Perrin RJ, Grossman M, Soares HD, Kling MA, Mailman M, Arnold SE, Narayan VA, Lee VM, Shaw LM, Baker D, Wittenberg GM, Trojanowski JQ, Wang LS Abstract INTRODUCTION: The dynamic range of cerebrospinal fluid (CSF) amyloid β (Aβ1-42) measurement does not parallel to cognitive... περισσότερα »

MicroRNA-101-3p suppresses cell proliferation, invasion and enhances chemotherapeutic sensitivity in salivary gland adenoid cystic carcinoma by targeting Pim-1.

Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
*MicroRNA-101-3p suppresses cell proliferation, invasion and enhances chemotherapeutic sensitivity in salivary gland adenoid cystic carcinoma by targeting Pim-1.* Am J Cancer Res. 2015;5(10):3015-29 Authors: Liu XY, Liu ZJ, He H, Zhang C, Wang YL Abstract MicroRNAs (miRNAs) play critical roles in carcinogenesis and tumor progression. Recent research has revealed miR-101-3p as an important regulator in several cancers. Nevertheless, its function in salivary gland Adenoid cystic carcinoma (ACC), a relatively rare malignance with poor long-term survival rate arisen in head and neck...περισσότερα »

Sclerosing Lesions of the Orbit: A Review.

Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
*Sclerosing Lesions of the Orbit: A Review.* Middle East Afr J Ophthalmol. 2015 Oct-Dec;22(4):447-51 Authors: Lokdarshi G, Pushker N, Bajaj MS Abstract Orbital sclerosing inflammation is a distinct group of pathologies characterized by indolent growth with minimal or no signs of inflammation. However, contrary to earlier classifications, it should not be considered a chronic stage of acute inflammation. Although rare, orbital IgG4-related disease has been associated with systemic sclerosing pseudotumor-like lesions. Possible mechanisms include autoimmune and IgG4 related defectiv... περισσότερα »

Lymphoepithelioma-like carcinoma of the urinary bladder: A rare case report.

Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
*Lymphoepithelioma-like carcinoma of the urinary bladder: A rare case report.* Urol Ann. 2015 Oct-Dec;7(4):516-9 Authors: Raphael V, Jitani AK, Sailo SL, Vakha M Abstract Bladder cancers are the second most common urogenital malignancy, its most common type being urothelial carcinoma. Lymphoepithelioma-like carcinoma (LELC) which is commonly described in the nasopharynx is a very rare presentation in the bladder. Diagnosis of this entity poses a histopathological challenge. Nonetheless, the correct diagnosis is important as it implies a different therapeutic approach with the po... περισσότερα »

Thyroid cancer in a long-term nonprogressor HIV-1 infection.

Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
*Thyroid cancer in a long-term nonprogressor HIV-1 infection.* Indian J Sex Transm Dis. 2015 Jul-Dec;36(2):195-7 Authors: Phatak UA, Chitale PV, Jagdale RV Abstract Long-term non-progressor HIV infection (LTNP-HIV) is seen in <1 percent of HIV-afflicted population. There are definite criteria for the diagnosis of LTNP-HIV. Malignancies either solid tumors or haematological cancers have not been reported in such population. We report here a rare case of follicular thyroid carcinoma in LTNP-HIV infection. She never had any opportunistic infections. She did not receive anti-retrovir... περισσότερα »

Patterns and functional implications of rare germline variants across 12 cancer types.

Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
*Patterns and functional implications of rare germline variants across 12 cancer types.* Nat Commun. 2015;6:10086 Authors: Lu C, Xie M, Wendl MC, Wang J, McLellan MD, Leiserson MD, Huang KL, Wyczalkowski MA, Jayasinghe R, Banerjee T, Ning J, Tripathi P, Zhang Q, Niu B, Ye K, Schmidt HK, Fulton RS, McMichael JF, Batra P, Kandoth C, Bharadwaj M, Koboldt DC, Miller CA, Kanchi KL, Eldred JM, Larson DE, Welch JS, You M, Ozenberger BA, Govindan R, Walter MJ, Ellis MJ, Mardis ER, Graubert TA, Dipersio JF, Ley TJ, Wilson RK, Goodfellow PJ, Raphael BJ, Chen F, Johnson KJ, Parvin JD, Ding... περισσότερα »

[A case of the successful function-preserving treatment of hyoid bone chondrosarcoma].

Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
Related Articles *[A case of the successful function-preserving treatment of hyoid bone chondrosarcoma].* Vestn Otorinolaringol. 2015;80(5):91-2 Authors: Klochikhin AL, Klochikhin MA, Kuleshov BY Abstract The authors report a case of the successful function-preserving treatment of a rare neck tumour, chondrosarcoma originating from the hyoid bone. The proposed combined treatment allowed to preserve the respiratory, voice-generating and protective functions of the larynx. The dynamic follow up failed to reveal the development of relapse or metastases during 1 year after surgery. ... περισσότερα »

Insulinoma in a patient with type 2 diabetes mellitus.

Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
Related Articles *Insulinoma in a patient with type 2 diabetes mellitus.* Acta Med Iran. 2015;53(5):317-9 Authors: Ghafoori S, Lankarani M Abstract Insulinoma in a patient with pre-existing diabetes is extremely rare. Only a small number of cases have been reported all over the world. We report a case of insulinoma in a patient with type 2 diabetes. A 63-year-old female was diagnosed to have diabetes mellitus six years ago, she was given metformin and sulphonylurea to control her glycemia, she had adequate glycemic control for many years, but thereafter, the patient has experien... περισσότερα »

[Multiple endocrine neoplasia type 2B].

Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
[image: http:--http://ift.tt/1PjZjdS] Related Articles *[Multiple endocrine neoplasia type 2B].* Ned Tijdschr Geneeskd. 2015;159:A7719 Authors: Pijnenburg-Kleizen KJ, van Santen HM, Koolen DA, Claahsen-van der Grinten HL Abstract BACKGROUND: Multiple endocrine neoplasia type 2b (MEN2B) is a rare syndrome characterised by the occurrence of medullary thyroid carcinoma at a young age in all patients, and phaeochromocytoma at a later age in half of the patients. Once a medullary thyroid carcinoma causes symptoms, it has usually already metastasised to the lymph nodes and curative tre... περισσότερα »

Laparoscopic Treatment of Sclerosing Stromal Tumor of the Ovary in a Woman With Gorlin-Goltz Syndrome: A Case Report and Review of the Literature.

Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
[image: http:--linkinghub.elsevier.com-ihub-imag] Related Articles *Laparoscopic Treatment of Sclerosing Stromal Tumor of the Ovary in a Woman With Gorlin-Goltz Syndrome: A Case Report and Review of the Literature.* J Minim Invasive Gynecol. 2015 Jul-Aug;22(5):892-5 Authors: Grechi G, Clemente N, Tozzi A, Ciavattini A Abstract Gorlin-Goltz syndrome is a rare hereditary multisystemic disease. Multiple basal cell carcinomas, odontogenic keratocysts, and skeletal abnormalities are the main clinical manifestations of the syndrome, but several organs can be involved. Moreover, this con... περισσότερα »

Invasive, atypical and aggressive pituitary adenomas and carcinomas.

Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
[image: http:--linkinghub.elsevier.com-ihub-imag] Related Articles *Invasive, atypical and aggressive pituitary adenomas and carcinomas.* Endocrinol Metab Clin North Am. 2015 Mar;44(1):99-104 Authors: Sav A, Rotondo F, Syro LV, Di Ieva A, Cusimano MD, Kovacs K Abstract Aggressive pituitary adenomas have a high risk of recurrence, a lack of therapeutic response, and resistance to conventional treatment. So far, no satisfactory biomarkers are available for predicting their behavior. Some specific pituitary adenoma histotypes are more prone to follow an aggressive behavior. Pituitary...περισσότερα »

Comparison of the KIR3DS1/Bw4 distribution in Chinese healthy and acute myeloid leukemia individuals.

Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
[image: http:--linkinghub.elsevier.com-ihub-imag] Related Articles *Comparison of the KIR3DS1/Bw4 distribution in Chinese healthy and acute myeloid leukemia individuals.* Hum Immunol. 2015 Mar;76(2-3):79-82 Authors: Tao S, He Y, Zhang W, Wang W, He J, Han Z, Chen N, Dong L, He J, Zhu F, Lv H Abstract Killer cell immunoglobulin like receptor (KIR) 3DS1 is one of the most important activating receptors and some studies revealed that KIR3DS1 combined with HLA ligand was not related to acute myeloid leukemia (AML), but rare data was reported in Chinese population. In this study, KIR3...περισσότερα »

Epithelioid trophoblastic tumor: an unusual malignancy of ovary.

Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
Related Articles *Epithelioid trophoblastic tumor: an unusual malignancy of ovary.* J Coll Physicians Surg Pak. 2014 Nov;24 Suppl 3:S201-3 Authors: Mahmood H, Faheem M, Tahir M, Arif S, Mahmood S, Irfan J Abstract Epithelioid Trophoblastic Tumor (ETT) is a distinct but rare variety of gestational trophoblastic tumors. Misdiagnosis delays effective treatment and affects the survival. The case being reported here involved a 43 years old lady presented with 4 months history of intermenstrual per vaginal bleeding and 6 weeks amenorrhea. Workup has revealed pelvic mass. The patient un...περισσότερα »

Mixed ovarian germ cell tumor composed of immature teratoma, yolk sac tumor and embryonal carcinoma.

Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
Related Articles *Mixed ovarian germ cell tumor composed of immature teratoma, yolk sac tumor and embryonal carcinoma.* J Coll Physicians Surg Pak. 2014 Nov;24 Suppl 3:S198-200 Authors: Wang Y, Zhou F, Qian Z, Qing J, Zhao M, Huang L Abstract We report the case of a 19-year-old woman experiencing lower abdominal distension and pain. Laboratory tests indicated elevated serum levels of Alpha-Fetoprotein (AFP) and human Chorionic Gonadotropin (hCG). A large mass was detected in the abdomen by physical examination and by transvaginal ultrasonography. Exploratory laparotomy was perfor... περισσότερα »

Incidentally discovered giant mucocele of the appendix.

Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
Related Articles *Incidentally discovered giant mucocele of the appendix.* J Coll Physicians Surg Pak. 2014 Nov;24 Suppl 3:S196-7 Authors: Harris SH, Khan R, Ansari MM, Maheshwari V Abstract Mucocele of the appendix is a rare but well-recognized entity that can mimic several common clinical conditions or present as an incidental radiological or surgical finding at laparotomy. Mucoceles are characterized by distension of the lumen due to accumulation of mucoid substance. They can result from mucosal hyperplasia, mucinous cystadenoma, or mucinous cystadenocarcinoma. If untreated, t...περισσότερα »

Toxic secretions from intracranial tumor damage the inner ear

Αλέξανδρος ΣφακιανάκηςστοAudiology by Alexandros G. SfakianakisΠριν από 1 ώρα
Researchers discover new mechanism of vestibular schwannoma that causes hearing loss, introduce new direction for therapy. from #Audiology via ola Kala on Inoreader http://ift.tt/1QHhU7g via IFTTT

Toxic secretions from intracranial tumor damage the inner ear

Αλέξανδρος ΣφακιανάκηςστοAudiology by Alexandros G. SfakianakisΠριν από 1 ώρα
Researchers discover new mechanism of vestibular schwannoma that causes hearing loss, introduce new direction for therapy. from #Audiology via ola Kala on Inoreader http://ift.tt/1QHhU7g via IFTTT

The p.Cys169Tyr variant of connexin 26 is not a polymorphism.

Αλέξανδρος ΣφακιανάκηςστοAudiology by Alexandros G. SfakianakisΠριν από 1 ώρα
[image: http:--highwire.stanford.edu-icons-exter] [image: http:--highwire.stanford.edu-icons-exter] [image: http:--http://ift.tt/1Fkw4zC]Related Articles *The p.Cys169Tyr variant of connexin 26 is not a polymorphism.* Hum Mol Genet. 2015 May 1;24(9):2641-8 Authors: Zonta F, Girotto G, Buratto D, Crispino G, Morgan A, Abdulhadi K, Alkowari M, Badii R, Gasparini P, Mammano F Abstract Mutations in the GJB2 gene, which encodes the gap junction protein connexin 26 (Cx26), are the primary cause of hereditary prelingual hearing impairment. Here, the p.Cys169Tyr missense mutation of Cx26 (... περισσότερα »

The p.Cys169Tyr variant of connexin 26 is not a polymorphism.

Αλέξανδρος ΣφακιανάκηςστοAudiology by Alexandros G. SfakianakisΠριν από 1 ώρα
[image: http:--highwire.stanford.edu-icons-exter] [image: http:--highwire.stanford.edu-icons-exter] [image: http:--http://ift.tt/1Fkw4zC]Related Articles *The p.Cys169Tyr variant of connexin 26 is not a polymorphism.* Hum Mol Genet. 2015 May 1;24(9):2641-8 Authors: Zonta F, Girotto G, Buratto D, Crispino G, Morgan A, Abdulhadi K, Alkowari M, Badii R, Gasparini P, Mammano F Abstract Mutations in the GJB2 gene, which encodes the gap junction protein connexin 26 (Cx26), are the primary cause of hereditary prelingual hearing impairment. Here, the p.Cys169Tyr missense mutation of Cx26 (... περισσότερα »

Cultural Adaptation Quality of Family Life Scale for the Brazilian Portuguese.

Αλέξανδρος ΣφακιανάκηςστοAudiology by Alexandros G. SfakianakisΠριν από 1 ώρα
*Cultural Adaptation Quality of Family Life Scale for the Brazilian Portuguese.* Codas. 2015 Dec;27(6):534-540 Authors: Jorge BM, Levy CC, Granato L Abstract Purpose To culturally adapt the Family Quality of Life Scale to the Brazilian Portuguese version and evaluate the instrument reliability and family quality of life of those who have children with hearing loss. Methods The process of cultural adaptation of the scale followed the steps of the Guidelines for the Process of Cross-Cultural Adaptation of Self-Report Measure. It was conducted in three stages: translation, back tra... περισσότερα »

Late morbidity in long-term survivors of childhood brain tumors: a nationwide registry-based study in Finland.

Αλέξανδρος ΣφακιανάκηςστοAudiology by Alexandros G. SfakianakisΠριν από 1 ώρα
[image: http:--highwire.stanford.edu-icons-exter]Related Articles *Late morbidity in long-term survivors of childhood brain tumors: a nationwide registry-based study in Finland.* Neuro Oncol. 2015 May;17(5):747-56 Authors: Gunn ME, Lähdesmäki T, Malila N, Arola M, Grönroos M, Matomäki J, Lähteenmäki PM Abstract BACKGROUND: The population of long-term survivors of childhood brain tumors (BTs) is growing. The aim of our study was to evaluate late-appearing morbidity in BT survivors. METHODS: Patients diagnosed with a BT at the age of 0-15 years between 1970 and 2004, and surviving at... περισσότερα »

Middle and inner ear malformations in two siblings exposed to valproic acid during pregnancy: a case report.

Αλέξανδρος ΣφακιανάκηςστοAudiology by Alexandros G. SfakianakisΠριν από 1 ώρα
[image: http:--linkinghub.elsevier.com-ihub-imag]Related Articles *Middle and inner ear malformations in two siblings exposed to valproic acid during pregnancy: a case report.* Int J Pediatr Otorhinolaryngol. 2014 Nov;78(11):2007-10 Authors: Van Houtte E, Casselman J, Janssens S, De Kegel A, Maes L, Dhooge I Abstract Valproic acid (VPA) is a known teratogenic drug. Exposure to VPA during the pregnancy can lead to a distinct facial appearance, a cluster of major and minor anomalies and developmental delay. In this case report, two siblings with fetal valproate syndrome and a mild con...περισσότερα »

Xenon anaesthesia in a patient with susceptibility to malignant hyperthermia: A case report

Alexandros G. SfakianakisστοAnaesthesiologyΠριν από 1 ώρα
[image: image]No abstract available from Anaesthesia via ola Kala on Inoreader http://ift.tt/1QWTPHK via IFTTT

The finding of an undiagnosed long segment tracheal stenosis in a cyanotic child undergoing an arterial switch operation and VSD closure

Alexandros G. SfakianakisστοΟγκολογίαΠριν από 1 ώρα
This report details the case of a 2-month-old baby boy with known cyanotic congenital heart disease (double outlet right ventricle with subpulmonary ventricular septal defect, VSD) in whom tracheal stenosis was undetected, being found later on failed intubation while undergoing anaesthesia for an arterial switch operation and VSD closure. As a result, the cardiac surgery was postponed. Such an association between congenital heart disease and tracheal stenosis has been reported but remains exceptionally rare. The baby subsequently underwent a slide tracheoplasty the next day and had... περισσότερα »

Removal of black stains from teeth by photodynamic therapy: clinical and microbiological analysis

Alexandros G. SfakianakisστοΟγκολογίαΠριν από 1 ώρα
Black-pigmented bacteria (BPB) are Gram-negative anaerobic, non-motile, proteolytic rods strongly implicated in the pathogenesis of periodontal disease. Although pigments are produced in vitro, black pigmentation is rarely found clinically. However, it may compromise aesthetics and contribute to gingival inflammation. The aim of this report is to describe a clinical case of a 10-year-old boy showing black pigmentation covering all teeth and to propose an alternative therapy for removal of black pigmentation, based on photodynamic therapy (PDT). In order to perform microbiological ... περισσότερα »

Pulmonary 'mercury embolism

Alexandros G. SfakianakisστοΟγκολογίαΠριν από 1 ώρα
Description A 35-year-old woman presented with anasarca and lower limb paraesthesias for 3 months. There was history of daily oral intake of 10–15 g of some indigenous preparation for low backache during the 2 months prior to current symptoms. On physical examination, respiratory rate was 18 breaths/min and oxygen saturation on room air was 95%. Serum creatinine was 1.4 mg/dL. Urine examination showed nephrotic proteinuria and chest radiograph demonstrated numerous small radiopaque densities (figure 1). High-resolution CT showed multiple metallic spherules diffusely scattered th...περισσότερα »

upper respiratory tract infection; +44 new citations

Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
44 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: *upper respiratory tract infection* These pubmed results were generated on 2015/12/23 PubMed comprises more than 24 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites. from #PubMed 2 via ola Kala on Inoreader http://ift.tt/QGMHBq(((upper%20respiratory%20tract%20infection)%20AND%20%222015%2F12%2F22%2006.13%22%5B...περισσότερα »

The HABP2 G534E variant is an unlikely cause of familial non-medullary thyroid cancer.

Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
*The HABP2 G534E variant is an unlikely cause of familial non-medullary thyroid cancer.* J Clin Endocrinol Metab. 2015 Dec 21;:jc20153928 Authors: Sahasrabudhe R, Stultz J, Williamson J, Lott P, Estrada A, Bohorquez M, Palles C, Polanco-Echeverry G, Jaeger E, Martin L, Magdalena Echeverry M, Tomlinson I, Carvajal-Carmona LG, TCUKIN Abstract CONTEXT: A recent study reported the non-synonymous G534E (rs7080536, allele A) variant in the HABP2 gene as causal in familial non-medullary thyroid cancer (NMTC). OBJECTIVE: The objective of this study was to evaluate the causality of HABP2...περισσότερα »

IJERPH, Vol. 13, Pages 60: Impact of ASUMA Intervention on HIV Risk Behaviors among Puerto Rican Adolescents

orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 1 ώρα
The purpose of this manuscript is to assess and compare HIV risk behaviors among early adolescents after a three-year pilot study. A total of 135 public and private junior high schools students completed the intervention protocol. A self-administered questionnaire was given at baseline and at the end of the third year (fourth measure). Descriptive and… Continue reading IJERPH, Vol. 13, Pages 60: Impact of ASUMA Intervention on HIV Risk Behaviors among Puerto Rican Adolescents

Sensitivity during the forced swim test is a key factor in evaluating the antidepressant effects of abscisic acid in mice

orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 1 ώρα
Publication date: 1 March 2016 Source:Behavioural Brain Research, Volume 300 Author(s): Cong-Cong Qi, Yu-Mian Shu, Fang-Han Chen, Yu-Qiang Ding, Jiang-Ning Zhou Abscisic acid (ABA), a crucial phytohormone, is distributed in the brains of mammals and has been shown to have antidepressant effects in the chronic unpredictable mild stress test. The forced swim test (FST) is… Continue reading Sensitivity during the forced swim test is a key factor in evaluating the antidepressant effects of abscisic acid in mice

IJERPH, Vol. 13, Pages 55: The Genetic Diversity and Evolution of HIV-1 Subtype B Epidemic in Puerto Rico

orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 1 ώρα
HIV-1 epidemics in Caribbean countries, including Puerto Rico, have been reported to be almost exclusively associated with the subtype B virus (HIV-1B). However, while HIV infections associated with other clades have been only sporadically reported, no organized data exist to accurately assess the prevalence of non-subtype B HIV-1 infection. We analyzed the nucleotide sequence data… Continue reading IJERPH, Vol. 13, Pages 55: The Genetic Diversity and Evolution of HIV-1 Subtype B Epidemic in Puerto Rico

EphB2 reverse signaling regulates learned opiate tolerance via hippocampal function

orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 1 ώρα
Publication date: 1 March 2016 Source:Behavioural Brain Research, Volume 300 Author(s): Sofia Huroy, Ashlin Kanawaty, Lilia Magomedova, Carolyn L. Cummins, Susan R. George, Derek van der Kooy, Jeffrey T. Henderson Despite significant progress, many uncertainties remain regarding molecular and cellular mechanisms governing opiate tolerance. We report that loss of EphB2 receptor reverse signaling results in… Continue reading EphB2 reverse signaling regulates learned opiate tolerance via hippocampal function

Low rate of job retention following colorectal cancer diagnosis in the US https://t.co/UQGRRPZVfB

orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 1 ώρα
Low rate of job retention following colorectal cancer diagnosis in the US https://t.co/UQGRRPZVfB from #ORL-AlexandrosSfakianakis via simeraentaxei on Inoreader http://twitter.com/ecancer/status/679615859904671744 via IFTTT

Removal of black stains from teeth by photodynamic therapy: clinical and microbiological analysis

orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 1 ώρα
Black-pigmented bacteria (BPB) are Gram-negative anaerobic, non-motile, proteolytic rods strongly implicated in the pathogenesis of periodontal disease. Although pigments are produced in vitro, black pigmentation is rarely found clinically. However, it may compromise aesthetics and contribute to gingival inflammation. The aim of this report is to describe a clinical case of a 10-year-old boy showing… Continue reading Removal of black stains from teeth by photodynamic therapy: clinical and microbiological analysis

RT @AmerGeriatrics : Is it time to start warning older adults of ties between surgery and cognitive dysfunction? https://t.co/AkpD1NvfYx htt…

orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 1 ώρα
RT @AmerGeriatrics : Is it time to start warning older adults of ties between surgery and cognitive dysfunction? https://t.co/AkpD1NvfYx htt… from #ORL-AlexandrosSfakianakis via simeraentaxei on Inoreader http://twitter.com/ecancer/status/679608157769961472 via IFTTT

Pulmonary ‘mercury embolism

orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 1 ώρα
Description A 35-year-old woman presented with anasarca and lower limb paraesthesias for 3 months. There was history of daily oral intake of 10–15 g of some indigenous preparation for low backache during the 2 months prior to current symptoms. On physical examination, respiratory rate was 18 breaths/min and oxygen saturation on room air was 95%.… Continue reading Pulmonary ‘mercury embolism

Learn all about next year’s ecancer radiotherapy symposium in Santiago https://t.co/GbMiABya7r https://t.co/WxauLxBH4b

orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 1 ώρα
Learn all about next year’s ecancer radiotherapy symposium in Santiago https://t.co/GbMiABya7r https://t.co/WxauLxBH4b from #ORL-AlexandrosSfakianakis via simeraentaxei on Inoreader http://twitter.com/ecancer/status/679602647389843457 via IFTTT

A unilateral purple urine bag syndrome in a patient with bilateral nephrostomy tubes

orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 1 ώρα
A change in the colour of urine is always of clinical significance, and a source of concern for the patient and his physician. Among the different urine colours observed, purple is the least common. Although purple discolouration of a catheter and a urine bag is an uncommon finding, it was reported in the literature as… Continue reading A unilateral purple urine bag syndrome in a patient with bilateral nephrostomy tubes

High drowsy driving crash risk on daytime commute after night work

Alexandros G. SfakianakisστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 1 ώρα
Brigham and Women's Hospital from Emergency Medicine via ola Kala on Inoreader http://ift.tt/1NLg2Ep via IFTTT

Severe supratentorial intracerebral hemorrhage: factors related to brain death development

Alexandros G. SfakianakisστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 1 ώρα
Transplantation Proceedings from Emergency Medicine via ola Kala on Inoreader http://ift.tt/1O8YW73 via IFTTT

Prothrombotic state in patients with severe and prednisolone-dependent asthma

Alexandros G. SfakianakisστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 1 ώρα
The Journal of Allergy and Clinical Immunology from Emergency Medicine via ola Kala on Inoreader http://ift.tt/1NLg2Eh via IFTTT

Two doses of tranexamic acid reduce blood transfusion in complex spine surgery: a prospective randomized study

Alexandros G. SfakianakisστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 1 ώρα
Spine from Emergency Medicine via ola Kala on Inoreader http://ift.tt/1NLg2Eb via IFTTT

Successful delayed treatment of the traumatic orbital apex syndrome by nasal endoscopic decompression surgery

Alexandros G. SfakianakisστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 1 ώρα
Indian Journal of Ophthalmology from Emergency Medicine via ola Kala on Inoreader http://ift.tt/1O8YXb9 via IFTTT

Incidence, aetiology and mortality secondary to hypertensive emergencies in a large-scale referral centre in Israel (1991–2010)

Alexandros G. SfakianakisστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 1 ώρα
Journal of Human Hypertension from Emergency Medicine via ola Kala on Inoreader http://ift.tt/1NLfZIE via IFTTT

PTSD, cyberbullying, and peer violence: Prevalence and correlates among adolescent emergency department patients

Alexandros G. SfakianakisστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 1 ώρα
General Hospital Psychiatry from Emergency Medicine via ola Kala on Inoreader http://ift.tt/1O8YXaX via IFTTT

Role confusion and self assessment in interprofessional trauma teams

Alexandros G. SfakianakisστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 1 ώρα
The American Journal of Surgery from Emergency Medicine via ola Kala on Inoreader http://ift.tt/1O8YXaV via IFTTT

Autonomic dysfunction elicited by a medulla oblongata injury after fourth ventricle tumor surgery in a pediatric patient

Alexandros G. SfakianakisστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 1 ώρα
Autonomic Neuroscience: Basic and Clinical from Emergency Medicine via ola Kala on Inoreader http://ift.tt/1NLfZIs via IFTTT

Strategies implementation to reduce medicine preparation error rate in neonatal intensive care units

Alexandros G. SfakianakisστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 1 ώρα
European Journal of Pediatrics from Emergency Medicine via ola Kala on Inoreader http://ift.tt/1O8YUfr via IFTTT

A comparison of an opioid abuse screening tool and prescription drug monitoring data in the emergency department

Alexandros G. SfakianakisστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 1 ώρα
Drug and Alcohol Dependence from Emergency Medicine via ola Kala on Inoreader http://ift.tt/1O8YVzV via IFTTT

Point-of-care ultrasound in pediatric emergency medicine: What do fellows need to know?

Alexandros G. SfakianakisστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 1 ώρα
Clinical Pediatric Emergency Medicine from Emergency Medicine via ola Kala on Inoreader http://ift.tt/1NLfZsa via IFTTT

Exploring potential reasons for the temporal trend in dialysis-requiring AKI in the United States

Alexandros G. SfakianakisστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 1 ώρα
Clinical Journal of the American Society of Nephrology from Emergency Medicine via ola Kala on Inoreader http://ift.tt/1O8YUfb via IFTTT

Gunshot-associated fractures in children and adolescents treated at two level 1 pediatric trauma centers

Alexandros G. SfakianakisστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 1 ώρα
Journal of Pediatric Orthopaedics from Emergency Medicine via ola Kala on Inoreader http://ift.tt/1O8YVjx via IFTTT

Point-of-care ultrasound in resource-limited settings

Alexandros G. SfakianakisστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 1 ώρα
Clinical Pediatric Emergency Medicine from Emergency Medicine via ola Kala on Inoreader http://ift.tt/1O8YTYS via IFTTT

Acute Respiratory Distress Syndrome: A Rare Complication in Pediatric Diabetic Ketoacidosis

Alexandros G. SfakianakisστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 1 ώρα
The Indian Journal of Pediatrics from Emergency Medicine via ola Kala on Inoreader http://ift.tt/1NLg1QO via IFTTT

Medical first: Discovery of warning symptoms for usually fatal heart rhythm malfunction opens new window of opportunity for prevention

Alexandros G. SfakianakisστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 1 ώρα
Cedars-Sinai from Emergency Medicine via ola Kala on Inoreader http://ift.tt/1O8YTYG via IFTTT

The impact of drought on ozone dry deposition over eastern Texas

Publication date: February 2016 Source:Atmospheric Environment, Volume 127 Author(s): Ling Huang, Elena C. McDonald-Buller, Gary McGaughey, Yosuke Kimura, David T. Allen Dry deposition represents a critical pathway through which ground-level ozone is removed from the atmosphere. Understanding the effects of drought on ozone dry deposition is essential for air quality modeling and management in regions […]

Large fire emissions in summer over the southeastern US: Satellite measurements and modeling analysis

Publication date: February 2016 Source:Atmospheric Environment, Volume 127 Author(s): Tao Zeng, Zhen Liu, Yuhang Wang We apply satellite fire detection products and air quality modeling to study the contribution of fire emissions to ambient aerosol concentrations over the southeastern U.S. We find that satellite MODIS fire counts show more extensive summer burnings than suggested by […]

Effect of droplet deformation on inertial and thermophoretic capture of particles

Publication date: February 2016 Source:Atmospheric Environment, Volume 127 Author(s): Ao Wang, Qiang Song, Bingqiang Ji, Qiang Yao Falling droplets significantly deform during the wet deposition and wet scrubbing processes, which affects particle capture. On the basis of studies on the deformation of droplets falling at terminal velocity with typical diameters, the flow and the temperature […]

Isolated rupture of teres major in a goalkeeper

A complete rupture of the teres major is an extremely rare injury and rarely described in the literature. We report the first case of an isolated rupture of the teres major in a professional football goalkeeper. The diagnosis requires a high degree of suspicion and complementation by image examinations. Conservative treatment has a high success […]

Evaluating strategies to reduce urban air pollution

Publication date: February 2016 Source:Atmospheric Environment, Volume 127 Author(s): L. Duque, H. Relvas, C. Silveira, J. Ferreira, A. Monteiro, C. Gama, S. Rafael, S. Freitas, C. Borrego, A.I. Miranda During the last years, specific air quality problems have been detected in the urban area of Porto (Portugal). Both PM10 and NO2 limit values have been […]

Nager acrofacial dysostosis: a rare genetic disorder causing bilateral temperomandibular joint ankylosis in a 10-year-old girl

Description A 10-year-old girl presented to the oral medicine department, with restricted mouth opening since childhood. Her family history revealed that she was the third child born of a consanguineous marriage. She was born after an unremarkable pregnancy, with a birth weight of 2.3 kg. Physical examination revealed downslanting palpebral fissures, microretrognathia, malar hypoplasia, a […]

Effects of dust storm events on weekly clinic visits related to pulmonary tuberculosis disease in Minqin, China

Publication date: February 2016 Source:Atmospheric Environment, Volume 127 Author(s): Yun Wang, Ruoyu Wang, Jing Ming, Guangxiu Liu, Tuo Chen, Xinfeng Liu, Haixia Liu, Yunhe Zhen, Guodong Cheng Pulmonary tuberculosis (PTB) is a major public health problem in China. Minqin, a Northwest county of China, has a very high number of annual PTB clinic visits and […]

Non-syndromic primary maxillary peg central incisors with multiple wormian bones in a 6-year-old boy: an unusual presentation

Description The peg-shaped conical tooth is the supernumerary tooth most commonly found in the permanent dentition. It develops with root formation ahead of or at an equivalent stage to that of the permanent incisors and usually presents as a mesiodens.1 Tooth malformations such as conical incisors and conical canines are commonly seen in hypohidrotic ectodermal […]

Large fire emissions in summer over the southeastern US: Satellite measurements and modeling analysis

Publication date: February 2016 Source:Atmospheric Environment, Volume 127 Author(s): Tao Zeng, Zhen Liu, Yuhang Wang We apply satellite fire detection products and air quality modeling to study the contribution of fire emissions to ambient aerosol concentrations over the southeastern U.S. We find that satellite MODIS fire counts show more extensive summer burnings than suggested by […]

The finding of an undiagnosed long segment tracheal stenosis in a cyanotic child undergoing an arterial switch operation and VSD closure

This report details the case of a 2-month-old baby boy with known cyanotic congenital heart disease (double outlet right ventricle with subpulmonary ventricular septal defect, VSD) in whom tracheal stenosis was undetected, being found later on failed intubation while undergoing anaesthesia for an arterial switch operation and VSD closure. As a result, the cardiac surgery […]

Toxic secretions from intracranial tumor damage the inner ear

Alexandros G. SfakianakisστοΑκοή και ΙσορροπίαΠριν από 1 ώρα
Researchers discover new mechanism of vestibular schwannoma that causes hearing loss, introduce new direction for therapy. from #Audiology via ola Kala on Inoreader http://ift.tt/1QHhU7g via IFTTT

Suppression of lactate dehydrogenase A compromises tumor progression by downregulation of the Warburg effect in glioblastoma

Alexandros G. SfakianakisστοΝευρολογία κ' ΝευροχειρουργικήΠριν από 2 ώρες
[image: image]Reprogrammed glucose metabolism is an emerging hallmark of cancer cells, which show a unique metabolic phenotype known as the Warburg effect. Lactate dehydrogenase A (LDHA), a key enzyme in the glycolytic process, executes the final step by conversion of lactate into pyruvate. However, little is known about the roles of LDHA in human glioblastoma (GBM). In this study, we aimed to determine the effects of LDHA and elucidate related underlying mechanisms. Data derived from Oncomine database showed that LDHA is commonly upregulated in GBM tissues in comparison with corres... περισσότερα »

Identification of autoantibodies to glial fibrillary acidic protein in spinal cord injury patients

Alexandros G. SfakianakisστοΝευρολογία κ' ΝευροχειρουργικήΠριν από 2 ώρες
[image: image]Traumatic spinal cord injury (SCI) is a devastating injury causing significant morbidity and mortality. Experimental studies have demonstrated that SCI induced cellular damage and disruption of the blood–spinal cord barrier can initiate an autoimmune response. This response is thought to be pathogenic and contribute to poor outcome. The objective of this research was to investigate whether human SCI mounts an autoimmune response to self-antigens. Plasma samples were collected longitudinally from SCI patients (n=18) at acute (T1, from Neurology via xlomafota13 on Inorea...περισσότερα »

STAT3 degradation mediated by calcineurin involved in the neurotoxicity of isoflurane

Alexandros G. SfakianakisστοΝευρολογία κ' ΝευροχειρουργικήΠριν από 2 ώρες
[image: image]Isoflurane, a commonly used volatile anesthetic, causes widespread neuronal apoptosis in the developing brain of rodents. Signal transducer and activator of transcription-3 (STAT3) signaling is crucial for cell survival during the neural network establishment period. The aim of this study was to determine whether isoflurane would target STAT3 to deliver its neurotoxicity. Mice at postnatal day 7 and primary cortical neurons cultured for 5 days were treated with isoflurane. Our data showed that isoflurane exposure downregulated the STAT3 survival pathway in the brain of...περισσότερα »

Computations underlying sensorimotor learning

Alexandros G. SfakianakisστοΝευρολογία κ' ΝευροχειρουργικήΠριν από 2 ώρες
[image: S09594388.gif] Publication date: April 2016 *Source:*Current Opinion in Neurobiology, Volume 37 Author(s): Daniel M Wolpert, J Randall Flanagan The study of sensorimotor learning has a long history. With the advent of innovative techniques for studying learning at the behavioral and computational levels new insights have been gained in recent years into how the sensorimotor system acquires, retains, represents, retrieves and forgets sensorimotor tasks. In this review we highlight recent advances in the field of sensorimotor learning from a computational perspective. We focus... περισσότερα »

EphB2 reverse signaling regulates learned opiate tolerance via hippocampal function

Alexandros G. SfakianakisστοΝευρολογία κ' ΝευροχειρουργικήΠριν από 2 ώρες
[image: alertIcon.gif] Publication date: 1 March 2016 *Source:*Behavioural Brain Research, Volume 300 Author(s): Sofia Huroy, Ashlin Kanawaty, Lilia Magomedova, Carolyn L. Cummins, Susan R. George, Derek van der Kooy, Jeffrey T. Henderson Despite significant progress, many uncertainties remain regarding molecular and cellular mechanisms governing opiate tolerance. We report that loss of EphB2 receptor reverse signaling results in a marked acceleration of morphine tolerance in vivo. EphB2 null mice exhibited no significant difference in brain or blood morphine metabolism, mu opiate re...περισσότερα »

Effects of optimism on gambling in the rat slot machine task

Alexandros G. SfakianakisστοΝευρολογία κ' ΝευροχειρουργικήΠριν από 2 ώρες
[image: S01664328.gif] Publication date: 1 March 2016 *Source:*Behavioural Brain Research, Volume 300 Author(s): Dominik Rafa, Jakub Kregiel, Piotr Popik, Rafal Rygula Although gambling disorder is a serious social problem in modern societies, information about the behavioral traits that could determine vulnerability to this psychopathology is still scarce. In this study, we used a recently developed ambiguous-cue interpretation ​(ACI)​ paradigm to investigate whether 'optimism' and 'pessimism' as behavioral traits may determine the gambling-like behavior of rodents. In a series of A... περισσότερα »

Sensitivity during the forced swim test is a key factor in evaluating the antidepressant effects of abscisic acid in mice

Alexandros G. SfakianakisστοΝευρολογία κ' ΝευροχειρουργικήΠριν από 2 ώρες
[image: S01664328.gif] Publication date: 1 March 2016 *Source:*Behavioural Brain Research, Volume 300 Author(s): Cong-Cong Qi, Yu-Mian Shu, Fang-Han Chen, Yu-Qiang Ding, Jiang-Ning Zhou Abscisic acid (ABA), a crucial phytohormone, is distributed in the brains of mammals and has been shown to have antidepressant effects in the chronic unpredictable mild stress test. The forced swim test (FST) is another animal model that can be used to assess antidepressant-like behavior in rodents. Here, we report that the antidepressant effects of ABA are associated with sensitivities to the FST in...περισσότερα »

Modulation of cannabinoid signaling by amygdala α2-adrenergic system in fear conditioning

Alexandros G. SfakianakisστοΝευρολογία κ' ΝευροχειρουργικήΠριν από 2 ώρες
[image: S01664328.gif] Publication date: 1 March 2016 *Source:*Behavioural Brain Research, Volume 300 Author(s): Mohammad Nasehi, Majid Zamanparvar, Mohaddeseh Ebrahimi-Ghiri, Mohammad-Reza Zarrindast The noradrenergic system plays a critical role in the modulation of emotional state, primarily related to anxiety, arousal, and stress. Growing evidence suggests that the endocannabinoid system mediates stress responses and emotional homeostasis, in part, by targeting noradrenergic circuits. In addition, there is an interaction between the cannabinoid and noradrenergic system that has ... περισσότερα »

Possible contribution of epigenetic changes in the development of schizophrenia-like behavior in vasopressin-deficient Brattleboro rats

Alexandros G. SfakianakisστοΝευρολογία κ' ΝευροχειρουργικήΠριν από 2 ώρες
[image: S01664328.gif] Publication date: 1 March 2016 *Source:*Behavioural Brain Research, Volume 300 Author(s): Kornél Demeter, Bibiána Török, Anna Fodor, János Varga, Szilamér Ferenczi, Krisztina J. Kovács, Ildikó Eszik, Viktor Szegedi, Dóra Zelena Schizophrenia-like symptoms were detected in vasopressin-deficient (di/di) Brattleboro rats, and it was also suggested that schizophrenia might have an epigenetic component. We aimed to clarify if epigenetic changes contribute to schizophrenia-like behavior of this strain.Behavioral (locomotion by telemetry, cognition by novel object rec... περισσότερα »