Syringomes
Publication date: Available online 28 March 2016 *Source:*Annales de Dermatologie et de Vénéréologie Author(s): B. Cribier from #Dermatology via alexandrossfakianakis on Inoreader http://ift.tt/1StqJj0 via IFTTT
Aplasie cutanée congénitale et antithyroïdiens de synthèse au cours de la grossesse : série de cas et revue de la littérature
Publication date: Available online 28 March 2016 *Source:*Annales de Dermatologie et de Vénéréologie Author(s): C. Sachs, M. Tebacher-Alt, M. Mark, B. Cribier, D. Lipsker IntroductionL'aplasie cutanée congénitale (ACC) après exposition in utero aux antithyroïdiens de synthèse (ATS) de type méthimazole/carbimazole (MTZ/CBZ) est décrite depuis 1972. Elle s'intègre actuellement dans le concept d'embryopathie au MTZ/CMZ, mais reste mal caractérisée et discutée. À l'occasion de deux cas observés dans un court laps de temps, nous avons effectué une revue de la littérature et interrogé la b...περισσότερα »
Superficial middle cerebral vein connection to the cavernous sinus
is not infrequent in brain arteriovenous malformations: an argument against their congenital origin?: Abstract IntroductionThe aim of this study was to test the hypothesis that the superficial middle cerebral vein (SMCV) is frequently absent or fails to connect with the cavernous sinus (CS) in the presence of brain arteriovenous malformations (AVMs), a frequently reported argument for the congenital origin of brain AVMs. MethodsThe SMCV was retrospectively compared between patients with a brain AVM and a control group. The presence or absence of the SMCV, its direct or indirec... περισσότερα »
The efficiency of botulinum toxin type A for the treatment of masseter muscle pain in patients with temporomandibular joint dysfunction and tension-type headache
*The efficiency of botulinum toxin type A for the treatment of masseter muscle pain in patients with temporomandibular joint dysfunction and tension-type headache: Temporomandibular joint dysfunction are often accompanied by symptoms of headache such as tension-type headache which is the most frequent spontaneous primary headache. Masseter muscle pain is commonly reporte... * Abstract Background *Temporomandibular joint dysfunction are often accompanied by symptoms of headache such as tension-type headache which is the most frequent spontaneous primary headache. Masseter muscle p...περισσότερα »
Population-based approaches to genetics of migraine
Population-based approaches to genetics of migraine: Background While the most accurate diagnosis of migraine typically requires a clinical interview guided by strict diagnostic criteria, an alternative approach that ascertains migraine by questionnaire in population-based settings has been instrumental in the discovery of common genetic variants influencing migraine risk. This result may be surprising. Population-based approaches are often criticized for limited ability to distinguish migraine from other forms of primary headache. It is thus useful to revisit prevailing ideas about... περισσότερα »
Favorable in vitro effects of combined IL-12 and IL-18 treatment on NK cell cytotoxicity and CD25 receptor expression in metastatic melanoma patients.
[image: http:--http://ift.tt/1NMOrDk] [image: http:--http://ift.tt/1Fkw4zC] Related Articles *Favorable in vitro effects of combined IL-12 and IL-18 treatment on NK cell cytotoxicity and CD25 receptor expression in metastatic melanoma patients.* J Transl Med. 2015;13:120 Authors: Mirjačić Martinović K, Babović N, Džodić R, Jurišić V, Matković S, Konjević G Abstract BACKGROUND: As IL-12 and IL-18 have important immunostimulatory role the aim of this study was to investigate their in vitro effects on functional and receptor characteristics of NK cells and their subsets in healthy ... περισσότερα »
Use of clinical next-generation sequencing to identify melanomas harboring SMARCB1 mutations.
[image: http:--media.wiley.com-assets-7315-19-Wi] Related Articles *Use of clinical next-generation sequencing to identify melanomas harboring SMARCB1 mutations.* J Cutan Pathol. 2015 May;42(5):308-17 Authors: Stockman DL, Curry JL, Torres-Cabala CA, Watson IR, Siroy AE, Bassett RL, Zou L, Patel KP, Luthra R, Davies MA, Wargo JA, Routbort MA, Broaddus RR, Prieto VG, Lazar AJ, Tetzlaff MT Abstract BACKGROUND: SMARCB1 (INI1/BAF47/SNF5) encodes a part of a multiprotein complex that regulates gene expression through chromatin remodeling. SMARCB1 expression is lost or downregulated in...περισσότερα »
Improving recognition of hepatic perivascular epithelioid cell tumor: Case report and literature review.
[image: http:--http://ift.tt/1YyhL4R] [image: http:--http://ift.tt/1Fkw4zC] Related Articles *Improving recognition of hepatic perivascular epithelioid cell tumor: Case report and literature review.* World J Gastroenterol. 2015 May 7;21(17):5432-41 Authors: Maebayashi T, Abe K, Aizawa T, Sakaguchi M, Ishibashi N, Abe O, Takayama T, Nakayama H, Matsuoka S, Nirei K, Nakamura H, Ogawa M, Sugitani M Abstract A 58-year-old man presented with the chief complaint of abdominal bloating and was incidentally found to have a liver tumor. As diagnostic imaging studies could not rule out mali... περισσότερα »
Thyroid Dysfunction in Children Exposed to Iodinated Contrast Media.
*Thyroid Dysfunction in Children Exposed to Iodinated Contrast Media.* J Clin Endocrinol Metab. 2016 Mar 28;:jc20161330 Authors: Barr ML, Chiu HK, Li N, Yeh MW, Rhee CM, Casillas J, Iskander PJ, Leung AM Abstract CONTEXT: Iodinated contrast media (ICM) is routinely used in imaging studies and contains several hundred-fold times the recommended daily allowance of iodine. OBJECTIVE: To determine whether children exposed to ICM have a higher risk of iodine-induced thyroid dysfunction. DESIGN: This was a single-institution case-control study, examining patients with incident thyroid d...περισσότερα »
Granuloma Annulare.
[image: http:--linkinghub.elsevier.com-ihub-imag] [image: http:--http://ift.tt/1UuR80f] Related Articles *Granuloma Annulare.* Dermatol Clin. 2015 Jul;33(3):315-29 Authors: Keimig EL Abstract Granuloma annulare (GA) is a noninfectious granulomatous skin condition that can present with a variety of cutaneous morphologies. It is characterized by collagen degeneration, mucin deposition, and palisaded or interstitial histiocytes. Although the mechanism underlying development of GA is unknown, studies point to a cell-mediated hypersensitivity reaction to an as-yet undetermined antige... περισσότερα »
Peroral endoscopic myotomy
Peroral endoscopic myotomy, 1000 cases later: pearls, pitfalls, and practical considerations: Eight years have passed since the introduction of the peroral endoscopy myotomy (POEM) procedure. POEM was initially received as an investigational procedure, but since the revelation of promising safety and efficacy data, it is becoming the preferred treatment for achalasia. With the recent completion of our 1,000th POEM procedure, we would like to share our experience and knowledge through the discussion of clinical pearls, pitfalls, and practical considerations.
Phénomène d’Arlequin associé à des anomalies neurologiques.Harlequin phenomenon consists of facial flush and erythrosis with unilateral sweating and pallor, associated with contralateral anhidrosis.
: un cas via ScienceDirect Publication: Annales de Dermatologie et de Vénéréologie Publication date: Available online 24 March 2016 *Source:*Annales de Dermatologie et de Vénéréologie Author(s): P. Lucas, L. Legendre, C. Pauwels, J. Mazereeuw-Hautier IntroductionLe phénomène d’Arlequin correspond à une érythrose faciale unilatérale avec flush et hypersudation, associées à une pâleur et une anhidrose controlatérales. Nous présentons le cas d’un enfant chez lequel ce syndrome était associé à un syndrome de Claude Bernard Horner controlatéral, une épilepsie et un retard mental et psychom... περισσότερα »
Reporting of symptoms in randomised controlled trials of atopic eczema treatments: a systematic review
Reporting of symptoms in randomised controlled trials of atopic eczema treatments: a systematic review: Abstract ‘Symptoms’ is a core outcome domain for atopic eczema (AE) trials, agreed by consensus as part of the Harmonising Outcome Measures for Eczema (HOME) initiative. To standardize and validate the core domain symptoms and symptom instruments for atopic eczema (AE) trials the HOME roadmap is followed. Its first step is to establish if and how symptoms have been measured in published AE treatment trials. Therefore the Global Resource for Eczema Trials (GREAT) database was used... περισσότερα »
Gait training of subacute stroke patients using a hybrid assistive limb: a pilot study.
*Gait training of subacute stroke patients using a hybrid assistive limb: a pilot study.* Disabil Rehabil Assist Technol. 2016 Mar 26;:1-8 Authors: Mizukami M, Yoshikawa K, Kawamoto H, Sano A, Koseki K, Asakwa Y, Iwamoto K, Nagata H, Tsurushima H, Nakai K, Marushima A, Sankai Y, Matsumura A Abstract Purpose To determine whether gait training with a hybrid assistive limb (HAL) as an exoskeleton robotic device was safe and could increase functional mobility and gait ability in subacute stroke patients. Methods The participants were eight patients with post-stroke hemiparesis whose ...περισσότερα »
Self-Reported Memory Complaints: A Comparison of Demented and Unimpaired Outcomes.
*Self-Reported Memory Complaints: A Comparison of Demented and Unimpaired Outcomes.* J Prev Alzheimers Dis. 2016 Mar;3(1):13-19 Authors: Kryscio RJ, Abner EL, Jicha GA, Nelson PT, Smith CD, Van Eldik LJ, Lou W, Fardo DW, Cooper GE, Schmitt FA Abstract BACKGROUND: Subjective memory complaints are common in aged persons, indicating an increased, but incompletely understood, risk for dementia. OBJECTIVE: To compare cognitive trajectories and autopsy results of individuals with subjective complaints after stratifying by whether a subsequent clinical dementia occurred. DESIGN: Observat... περισσότερα »
Bier's anemic spots, cyanosis with urticaria-like eruption (BASCULE) syndrome: a new entity?
Bier's anemic spots, cyanosis with urticaria-like eruption (BASCULE) syndrome: a new entity?: Abstract Bier's anemic spots (BAS) are characterized by multiple asymptomatic anemic white macules usually standing out against a cyanotic background and mainly distributed on the extensor surface of the upper and lower extremities.1 Herein, we report four cases of a new dermatosis characterized by BAS associated with cyanosis and urticaria-like eruption. A 14-year-old girl without relevant medical history was admitted for the evaluation of disseminated pruritic cutaneous lesions that had a... περισσότερα »
Secondary syphilis with skeletal involvement
Ostéite syphilitique chez un patient séronégatif pour le VIH via ScienceDirect Publication: Annales de Dermatologie et de Vénéréologie Publication date: Available online 25 March 2016 *Source:*Annales de Dermatologie et de Vénéréologie Author(s): C. Mignard, N. Litrowski, D. Carré, M. Midhat, N. Dupin, P. Bravard IntroductionLes observations de syphilis secondaire avec atteinte osseuse sont rares ; nous en rapportons un cas chez un patient immunocompétent.ObservationUn homme de 28ans homosexuel, sans antécédent notable, séronégatif pour le VIH, présentait une syphilis secondaire avec c... περισσότερα »
Favorable in vitro effects of combined IL-12 and IL-18 treatment on NK cell cytotoxicity and CD25 receptor expression in metastatic melanoma patients.
[image: http:--http://ift.tt/1NMOrDk] [image: http:--http://ift.tt/1Fkw4zC] Related Articles *Favorable in vitro effects of combined IL-12 and IL-18 treatment on NK cell cytotoxicity and CD25 receptor expression in metastatic melanoma patients.* J Transl Med. 2015;13:120 Authors: Mirjačić Martinović K, Babović N, Džodić R, Jurišić V, Matković S, Konjević G Abstract BACKGROUND: As IL-12 and IL-18 have important immunostimulatory role the aim of this study was to investigate their in vitro effects on functional and receptor characteristics of NK cells and their subsets in healthy ... περισσότερα »
Xanthine Oxidoreductase Function Contributes to Normal Wound Healing.
[image: http:--http://ift.tt/1Fkw4zC] Related Articles *Xanthine Oxidoreductase Function Contributes to Normal Wound Healing.* Mol Med. 2015;21:313-22 Authors: Madigan MC, McEnaney RM, Shukla AJ, Hong G, Kelley EE, Tarpey MM, Gladwin M, Zuckerbraun BS, Tzeng E Abstract Chronic, nonhealing wounds result in patient morbidity and disability. Reactive oxygen species (ROS) and nitric oxide (NO) are both required for normal wound repair, and derangements of these result in impaired healing. Xanthine oxidoreductase (XOR) has the unique capacity to produce both ROS and NO. We hypothesize... περισσότερα »
Genistein suppresses FLT4 and inhibits human colorectal cancer metastasis.
[image: http:--http://ift.tt/1kmBV5b] [image: http:--http://ift.tt/1Fkw4zC] Related Articles *Genistein suppresses FLT4 and inhibits human colorectal cancer metastasis.* Oncotarget. 2015 Feb 20;6(5):3225-39 Authors: Xiao X, Liu Z, Wang R, Wang J, Zhang S, Cai X, Wu K, Bergan RC, Xu L, Fan D Abstract Dietary consumption of genistein, found in soy, has been associated with a potentially protective role in colorectal cancer (CRC) development and progression. Herein we demonstrate that genistein will inhibit human CRC cell invasion and migration, that it does so at non-cytotoxic con... περισσότερα »
Adult-onset neuronal intranuclear hyaline inclusion disease is not rare in older adults.
*Adult-onset neuronal intranuclear hyaline inclusion disease is not rare in older adults.* Geriatr Gerontol Int. 2016 Mar;16 Suppl 1:51-6 Authors: Takahashi-Fujigasaki J, Nakano Y, Uchino A, Murayama S Abstract Neuronal intranuclear hyaline inclusion disease (NIHID) is a rare neurodegenerative disorder pathologically characterized by localized neuronal loss, and the presence of eosinophilic intranuclear inclusions in neurons and glial cells. NIHID is a heterogeneous disease entity. It is divided into three clinical subgroups: infantile, juvenile and adult forms. Recently, reports... περισσότερα »
Challenges, solutions, and recommendations for Alzheimer's disease combination therapy.
*Challenges, solutions, and recommendations for Alzheimer's disease combination therapy.* Alzheimers Dement. 2016 Mar 24; Authors: Hendrix JA, Bateman RJ, Brashear HR, Duggan C, Carrillo MC, Bain LJ, DeMattos R, Katz RG, Ostrowitzki S, Siemers E, Sperling R, Vitolo OV Abstract Given the complex neuropathology Alzheimer's disease (AD), combination therapy may be necessary for effective treatment. However, scientific, pragmatic, regulatory, and business challenges need to be addressed before combination therapy for AD can become a reality. Leaders from academia and industry, along ...περισσότερα »
Altered local field potential activity and serotonergic neurotransmission are further characteristics of the Flinders sensitive line rat model of depression.
[image: http:--linkinghub.elsevier.com-ihub-imag] Related Articles *Altered local field potential activity and serotonergic neurotransmission are further characteristics of the Flinders sensitive line rat model of depression.* Behav Brain Res. 2015 Sep 15;291:299-305 Authors: Voget M, Rummel J, Avchalumov Y, Sohr R, Haumesser JK, Rea E, Mathé AA, Hadar R, van Riesen C, Winter C Abstract A significant portion of patients suffering from major depression remains refractory to available antidepressant treatment strategies. This highlights the need for a better understanding of the un... περισσότερα »
Neurogenic pulmonary edema following Cryptococcal meningoencephalitis associated with HIV infection.
[image: http:--media.wiley.com-assets-7315-19-Wi] Related Articles *Neurogenic pulmonary edema following Cryptococcal meningoencephalitis associated with HIV infection.* Neuropathology. 2015 Aug;35(4):343-7 Authors: Kondo R, Sugita Y, Arakawa K, Nakashima S, Umeno Y, Todoroki K, Yoshida T, Takase Y, Kage M, Oshima K, Yano H Abstract Neurogenic pulmonary edema (NPE) is a clinical syndrome characterized by the acute onset of pulmonary edema following a significant central nervous system insult. Only a few cases of NPE after Cryptococcal meningitis have been reported. We report a ca... περισσότερα »
Schnitzler syndrome is a rare disease characterised by chronic hives (urticaria) and periodic fever, bone pain and joint pain (sometimes withjoint inflammation), weight loss, malaise, fatigue, swollen lymph glands and enlarged spleen and liver.
Schnitzler syndrome *From Wikipedia, the free encyclopedia* Schnitzler syndrome Classification and external resources ICD-9-CM *273.1* DiseasesDB *31345* eMedicine *derm/489* MeSH *D019873* *Schnitzler syndrome is a rare disease characterised by chronic hives (urticaria) and periodic fever, bone pain and joint pain (sometimes withjoint inflammation), weight loss, malaise, fatigue, swollen lymph glands and enlarged spleen and liver.[1]* *The urticarial rash is non-itching in more than half of cases, which is unusual for hives. It is most prominent on the trunk, arms and legs, sparing ...περισσότερα »
Inverted follicular keratosis (IFK)
Dermoscopy of inverted follicular keratosis: study of 12 cases: Summary Background Inverted follicular keratosis (IFK) is an uncommon benign tumour of the follicular infundibulum, which is often misdiagnosed clinically as other keratinizing tumours, and commonly diagnosed correctly by histopathology. There are few reports about the dermoscopic findings of this lesion. Aim To evaluate the dermoscopic features of IFK. Methods The dermoscopic structures and patterns in digital dermoscopic images of 12 histopathologically confirmed cases of IFK collected from 5 hospitals in Spain were ev... περισσότερα »
Aplasie cutanée congénitale et antithyroïdiens de synthèse au cours de la grossesse
: série de cas et revue de la littérature via ScienceDirect Publication: Annales de Dermatologie et de Vénéréologie Publication date: Available online 28 March 2016 *Source:*Annales de Dermatologie et de Vénéréologie Author(s): C. Sachs, M. Tebacher-Alt, M. Mark, B. Cribier, D. Lipsker IntroductionL’aplasie cutanée congénitale (ACC) après exposition in utero aux antithyroïdiens de synthèse (ATS) de type méthimazole/carbimazole (MTZ/CBZ) est décrite depuis 1972. Elle s’intègre actuellement dans le concept d’embryopathie au MTZ/CMZ, mais reste mal caractérisée et discutée. À l’occasion d... περισσότερα »
Wegener’s Granulomatosis Presenting with Unilateral Facial Nerve Palsy
A Case of Wegener’s granulomatosis or granulomatosis with polyangiitis is a necrotizing vasculitis affecting both arterioles and venules. The disease is characterized by the classical triad involving acute inflammation of the upper and lower respiratory tracts with renal involvement. However, the disease pathology can affect any organ system. This case presents Wegener’s granulomatosis presenting with facial nerve palsy as the first manifestation of the disease, which is rarely reported in medical literature.
Diffuse descending necrotising mediastinitis and pleural empyema secondary to acute odontogenic infection resulting in severe dysphagia
Diffuse descending necrotising mediastinitis and pleural empyema secondary to acute odontogenic infection resulting in severe dysphagia: We report a case of acute odontogenic sepsis in a 59-year-old man, presenting with diffuse, descending necrotising mediastinitis complicated by pleural empyema. Despite surviving the odds, his recovery was complicated by severe dysphagia, resulting in gastrostomy feeding for 6 months. Until now, severe dysphagia following descending necrotising mediastinitis has been unreported.
Coxiella burnetii spondylodiscitis
Disappearance of FDG uptake on PET scan after antimicrobial therapy could help for the diagnosis of Coxiella burnetii spondylodiscitis: Description A 55 year-old man was admitted for worsening of a chronic low back pain associated with L4-L5 anterolisthesis, despite taking non-steroidal anti-inflammatory drugs for several months. He had a medical history of high blood pressure and obesity (body mass index, 37 kg/m2). He lived in the countryside but had no direct contact with animals except his dog. There were no fever, chills, sweats or weight loss. C reactive protein (CRP) was <2.9... περισσότερα »
Sternoclavicular joint septic arthritis
Sternoclavicular joint septic arthritis with chest wall abscess in a healthy adult: a case report: Septic arthritis of the sternoclavicular joint is rare. It can be associated with serious complications such as osteomyelitis, chest wall abscess, and mediastinitis. In this report, we describe a case of an ot...
Neonatal Abdominal Hemangiomatosis: Propranolol beyond Infantile Hemangioma
Neonatal Abdominal Hemangiomatosis: Propranolol beyond Infantile Hemangioma: Hemangioma is the most common vascular tumor of infancy; presentation is often as cutaneous infantile hemangioma (IH). Cutaneous hemangioma is a clinical diagnosis. Most IHs follow a benign course, with complete involution without treatment in the majority of cases. Visceral hemangioma often involves the liver and manifests as a life-threatening disorder. Hepatic hemangiomas may be associated with high output cardiac failure, coagulopathy, and hepatomegaly which generally develop between 1 and 16 weeks of a... περισσότερα »
Thyroid Carcinoma Showing Thymic-Like Differentiation Causing Fracture of the Trachea
Thyroid Carcinoma Showing Thymic-Like Differentiation Causing Fracture of the Trachea: Thyroid carcinoma showing thymic-like differentiation (CASTLE) comprises a rare neoplasm of the thyroid gland which arises from ectopic thymic tissue or remnants of brachial pouches. CASTLE is regarded as an indolent neoplasm with a favorable prognosis, irrespective of its metastatic potential. Diagnosis is difficult as clinicopathological features have not been yet well-defined. Radiological findings are not specific and only immunohistochemical positivity for CD5 and CD117 staining is highly sug... περισσότερα »
THE TRIBES AND TRIBULATIONS OF LARYNGOPHARYNGEAL REFLUX: A REVIEW OF RECENT STUDIES WITH IMPLICATIONS FOR INTERDISCIPLINARY COLLABORATIONS BETWEEN OTOLARYNGOLOGISTS AND GASTROENTEROLOGISTS.
Related Articles *THE TRIBES AND TRIBULATIONS OF LARYNGOPHARYNGEAL REFLUX: A REVIEW OF RECENT STUDIES WITH IMPLICATIONS FOR INTERDISCIPLINARY COLLABORATIONS BETWEEN OTOLARYNGOLOGISTS AND GASTROENTEROLOGISTS.* Rev Med Chir Soc Med Nat Iasi. 2015 Oct-Dec;119(4):967-73 Authors: Bărboi OB, Prelipcean CC, Cobzeanu MD, Palade D, Albu-Soda A, Floria M, Chirilă I, Drug VL, Bălan G Abstract Laryngopharyngeal reflux has been recognized since 2006 (Montreal Consensus) as an extradigestive manifestation of gastroesophageal reflux disease. However, despite numerous research studies, the relat... περισσότερα »
A Meta-Analysis of Randomized Controlled Trials to Compare Long-Term Outcomes of Nissen and Toupet Fundoplication for Gastroesophageal Reflux Disease.
[image: http:--http://ift.tt/1II1iHB] [image: http:--http://ift.tt/1Fkw4zC] Related Articles *A Meta-Analysis of Randomized Controlled Trials to Compare Long-Term Outcomes of Nissen and Toupet Fundoplication for Gastroesophageal Reflux Disease.* PLoS One. 2015;10(6):e0127627 Authors: Tian ZC, Wang B, Shan CX, Zhang W, Jiang DZ, Qiu M Abstract AIM: In recent years, several studies with large sample sizes and recent follow-up data have been published comparing outcomes between laparoscopic Nissen fundoplication and laparoscopic Toupet fundoplication. It is now timely to be re-eval... περισσότερα »
[Risk-benefit of anti-reflux therapy in the premature infant].
[image: http:--linkinghub.elsevier.com-ihub-imag] *[Risk-benefit of anti-reflux therapy in the premature infant].* Arch Pediatr. 2015 May;22(5 Suppl 1):206-7 Authors: Mouterde O PMID: 26112594 [PubMed - indexed for MEDLINE] from Swallowing and Swallowing Disorders (Dysphagia) via a.lsfakia on Inoreader http://ift.tt/1VReSOB via IFTTT
EGJ outflow obstruction must be excluded in patients with high IRP and weak peristalsis.
[image: http:--http://ift.tt/1iA58YG] Related Articles *EGJ outflow obstruction must be excluded in patients with high IRP and weak peristalsis.* Turk J Gastroenterol. 2015 May;26(3):288 Authors: Sakin YS, Çelebi G, Kekilli M, Uygun A, Bağcı S PMID: 26006213 [PubMed - indexed for MEDLINE] from Swallowing and Swallowing Disorders (Dysphagia) via a.lsfakia on Inoreader http://ift.tt/1VRePTd via IFTTT
The last innovation in achalasia treatment; per-oral endoscopic myotomy.
[image: http:--http://ift.tt/1iA58YG] Related Articles *The last innovation in achalasia treatment; per-oral endoscopic myotomy.* Turk J Gastroenterol. 2015 May;26(3):218-23 Authors: Aslan F, Akpınar Z, Alper E, Atay A, Yurtlu DA, Çekiç C, Bor S, Ünsal B Abstract BACKGROUND/AIMS: Per-oral endoscopic myotomy (POEM) is a minimally invasive endoscopic treatment option for patients with achalasia and has been performed since 2010. It is less invasive than Heller myotomy and its use is spreading rapidly worldwide. We present our results of POEM that, to the best of our knowledge, are ... περισσότερα »
[Gastrointestinal foreign body in children].
[image: http:--http://ift.tt/1R8xNmj] Related Articles *[Gastrointestinal foreign body in children].* Rev Chil Pediatr. 2014 Dec;85(6):682-9 Authors: Muñoz F MP, Maluje J R, Saitua D F Abstract UNLABELLED: Gastrointestinal foreign bodies (FB) are frequent complaints in the emergency departments, with esophageal foreign bodies as the most frequent cases. Symptoms are varied and depend on the location of the FB, with several techniques available for removal. OBJECTIVE: To describe the FB removed by endoscopy in children as well as the consulting population characteristics. PATIENTS ... περισσότερα »
[Proarrhythmic effects of domperidone in infants: a systematic review].
Related Articles *[Proarrhythmic effects of domperidone in infants: a systematic review].* Farm Hosp. 2014 Sep-Oct;38(5):438-44 Authors: Caraballo L, Molina G, Weitz D, Piskulic L, Avila A, Marzi M Abstract AIMS: To assess the association of the use of domperidone in infants with QTc interval prolongation and proarrhythmic events. METHODS: A systematic search of the scientific literature was conducted without any date or language restriction. The electronic database MEDLINE and the sources LILACS, ScIELO and Cochrane library were consulted. RESULTS: From the twelve identified studi... περισσότερα »
Can Dysphagia Following Anterior Cervical Fusions With rhBMP-2 Be Reduced With Local Depomedrol Application?: A Prospective, Randomized, Placebo-Controlled, Double-Blind Trial.
*Can Dysphagia Following Anterior Cervical Fusions With rhBMP-2 Be Reduced With Local Depomedrol Application?: A Prospective, Randomized, Placebo-Controlled, Double-Blind Trial.* Spine (Phila Pa 1976). 2016 Apr;41(7):555-562 Authors: Edwards CC, Dean C, Edwards CC, Phillips D, Blight A Abstract STUDY DESIGN: A prospective, randomized, placebo-controlled, double-blind trial. OBJECTIVE: The aim of this study was to investigate whether the local administration of depomedrol decreases the severity of dysphagia after anterior cervical discectomy and fusion (ACDF) surgery using bone mo... περισσότερα »
Severe dysphagia, myalgia, and rash in a 55-year-old man.
*Severe dysphagia, myalgia, and rash in a 55-year-old man.* J Dtsch Dermatol Ges. 2016 Mar 28; Authors: Prossliner V, Philipp M, Moosbrugger V, Poewe W, Zangerle R, Wanschitz J, Schmuth M PMID: 27018866 [PubMed - as supplied by publisher] from Swallowing and Swallowing Disorders (Dysphagia) via a.lsfakia on Inoreader http://ift.tt/1VReSOK via IFTTT
[Anesthetic Management for a Patient with Stiff-person Syndrome].
*[Anesthetic Management for a Patient with Stiff-person Syndrome].* Masui. 2016 Feb;65(2):164-7 Authors: Nakamura K, Murao K, Kimoto-Shirakawa M, Takahira K, Toorabally F, Shingu K Abstract The stiff-person syndrome (SPS) is a rare autoimmune neurologic disorder that affects the gamma-aminobutyric acid (GABA) mediated inhibitory network in the central nervous system with anti-glutamic acid decarboxylase (GAD) antibodies. SPS is characterized by muscle rigidity and painful episodic spasms in axial and lower limb muscles. This case report describes successful peri-operative managem... περισσότερα »
THE TRIBES AND TRIBULATIONS OF LARYNGOPHARYNGEAL REFLUX: A REVIEW OF RECENT STUDIES WITH IMPLICATIONS FOR INTERDISCIPLINARY COLLABORATIONS BETWEEN OTOLARYNGOLOGISTS AND GASTROENTEROLOGISTS.
Related Articles *THE TRIBES AND TRIBULATIONS OF LARYNGOPHARYNGEAL REFLUX: A REVIEW OF RECENT STUDIES WITH IMPLICATIONS FOR INTERDISCIPLINARY COLLABORATIONS BETWEEN OTOLARYNGOLOGISTS AND GASTROENTEROLOGISTS.* Rev Med Chir Soc Med Nat Iasi. 2015 Oct-Dec;119(4):967-73 Authors: Bărboi OB, Prelipcean CC, Cobzeanu MD, Palade D, Albu-Soda A, Floria M, Chirilă I, Drug VL, Bălan G Abstract Laryngopharyngeal reflux has been recognized since 2006 (Montreal Consensus) as an extradigestive manifestation of gastroesophageal reflux disease. However, despite numerous research studies, the relat... περισσότερα »
[Risk-benefit of anti-reflux therapy in the premature infant].
[image: http:--linkinghub.elsevier.com-ihub-imag] *[Risk-benefit of anti-reflux therapy in the premature infant].* Arch Pediatr. 2015 May;22(5 Suppl 1):206-7 Authors: Mouterde O PMID: 26112594 [PubMed - indexed for MEDLINE] from Swallowing and Swallowing Disorders (Dysphagia) via a.lsfakia on Inoreader http://ift.tt/1VReSOB via IFTTT
EGJ outflow obstruction must be excluded in patients with high IRP and weak peristalsis.
[image: http:--http://ift.tt/1iA58YG] Related Articles *EGJ outflow obstruction must be excluded in patients with high IRP and weak peristalsis.* Turk J Gastroenterol. 2015 May;26(3):288 Authors: Sakin YS, Çelebi G, Kekilli M, Uygun A, Bağcı S PMID: 26006213 [PubMed - indexed for MEDLINE] from Swallowing and Swallowing Disorders (Dysphagia) via a.lsfakia on Inoreader http://ift.tt/1VRePTd via IFTTT
Low dose of lenalidmide and PI3K/mTOR inhibitor trigger synergistic cytoxicity in activated B cell-like subtype of diffuse large B cell lymphoma
Low dose of lenalidmide and PI3K/mTOR inhibitor trigger synergistic cytoxicity in activated B cell-like subtype of diffuse large B cell lymphoma: Abstract BackgroundActivated B cell-like subtype of diffuse large B cell lymphoma (ABC-DLBCL) presents aggressive clinical courses and poor prognosis. Targeting key pathways may raise the possibility of improving clinical outcomes. MethodsThe synergetic effects were assessed by CCK-8 assay and measured by isobologram analysis. The NVP-Bez235 and lenalidomide cytotoxicity were measured by flow cytometry, Western Blot and si-RNA transf...περισσότερα »
Temsirolimus in combination with metformin in patients with advanced/refractory cancers
Phase I dose escalation study of temsirolimus in combination with metformin in patients with advanced/refractory cancers: Abstract PurposeMammalian target of rapamycin (mTOR) inhibitors like temsirolimus may result in undesirable AKT upregulation. Metformin inhibits mTOR through different mechanisms and may enhance temsirolimus’s antitumor activity. We conducted an open-label phase I dose escalation trial of this drug combination in patients with advanced/refractory cancers. MethodsTemsirolimus, 25 mg weekly, was combined with an escalating daily dose of metformin (level 1: 500...περισσότερα »
Stereotactic Radiotherapy for Spinal Metastases
in the Postoperative Setting: A Secondary Analysis of Mature Phase I-II Trials via International Journal of Radiation Oncology*Biology*Physics Publication date: Available online 25 March 2016 *Source:*International Journal of Radiation Oncology*Biology*Physics Author(s): Randa Tao, Andrew J. Bishop, Zachary Brownlee, Pamela K. Allen, Stephen H. Settle, Eric L. Chang, Xin Wang, Behrang Amini, Nizar M. Tannir, Claudio Tatsui, Laurence D. Rhines, Paul D. Brown, Amol J. Ghia PurposeTo evaluate the outcomes of patients treated on prospective phase I-II protocols with postoperative stereotac... περισσότερα »
CISPLATIN VERSUS CARBOPLATIN
: COMPARATIVE REVIEW OF THERAPEUTIC MANAGEMENT IN SOLID MALIGNANCIES via Critical Reviews in Oncology/Hematology (open access) Publication date: Available online 24 March 2016 *Source:*Critical Reviews in Oncology/Hematology Author(s): Gwo Yaw Ho, Natasha Woodward, Jermaine I.G. Coward The platinum analogues, cisplatin and carboplatin, are among the most widely used chemotherapeutic agents in oncology. Both agents have a broad spectrum of clinical activity in numerous malignancies including gynaecological cancers, germ cell tumours, head and neck cancer, thoracic cancers and bladder can... περισσότερα »
Coffee consumption and the risk of cancer
in the Norwegian Women and Cancer (NOWAC) Study: AbstractAn association between coffee consumption and cancer has long been investigated. Coffee consumption among Norwegian women is high, thus this is a favorable population in which to study the impact of coffee on cancer incidence. Information on coffee consumption was collected from 91,767 women at baseline in the Norwegian Women and Cancer Study. These information were applied until follow-up information on coffee consumption, collected 6–8 years after baseline, became available. Multiple imputation was performed as a method fo... περισσότερα »
Factors associated with success of image-guided tumour biopsies
: Results from a prospective molecular triage study (MOSCATO-01) via ScienceDirect Publication: European Journal of Cancer Publication date: May 2016 *Source:*European Journal of Cancer, Volume 59 Author(s): Vania Tacher, Marie-Cécile Le Deley, Antoine Hollebecque, Frederic Deschamps, Philippe Vielh, Antoine Hakime, Ecaterina Ileana, Behnoush Abedi-Ardekani, Cécile Charpy, Christophe Massard, Silvia Rosellini, Dorota Gajda, Aljosa Celebic, Charles Ferté, Maud Ngo-Camus, Siham Gouissem, Valérie Koubi-Pick, Fabrice Andre, Gilles Vassal, Désirée Deandreis, Ludovic Lacroix, Jean-Charles So... περισσότερα »
Negative influence of programmed death-1-ligands on the survival of esophageal cancer patients treated with chemotherapy
Negative influence of programmed death-1-ligands on the survival of esophageal cancer patients treated with chemotherapy: [image: cover.gif?v=1&s=851fabfc577da741d1c2873e] Abstract The programmed death-1/programmed death-1ligands (PD-1/PD-Ls) pathway plays an important role in immunological tumor evasion. However, clinical significance of the PD-Ls (L1 and L2) expression in esophageal cancer treated with chemotherapy has not been fully investigated. We examined the expression of PD-Ls of the primary tumors obtained from 180 esophageal cancer patients who underwent radical resecti... περισσότερα »
Treatment of in-transit and metastatic melanoma in two patients treated with ipilimumab and topical imiquimod.
Treatment of in-transit and metastatic melanoma in two patients treated with ipilimumab and topical imiquimod.: Checkpoint blockade inhibitors have revolutionized the treatment of metastatic melanoma. Despite the success of these agents in improving the overall survival of patients with metastatic melanoma, not all patients achieve clinical benefit, leaving room for improvement. The presence of cutaneous metastases in patients with metastatic melanoma provides the unique opportunity to treat the cutaneous lesions with a local modality while simultaneously treating systemic disease w... περισσότερα »
macrophage; +28 new citations
28 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: *macrophage* These pubmed results were generated on 2016/03/29 PubMed comprises more than 24 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites. from Head and Neck on PubMed via xlomafota13 on Inoreader http://ift.tt/1RHtZUO via IFTTT
Safety of immune checkpoint inhibitors in patients with melanoma.
Safety of immune checkpoint inhibitors in Chinese patients with melanoma.: This study aimed to determine the tolerability of Chinese melanoma patients, particularly those with hepatitis B virus (HBV) infection, to immune checkpoint inhibitor therapy. Patients with metastatic melanoma who received anti-cytotoxic T lymphocyte-associated antigen-4 antibody (ipilimumab) or anti-programmed death 1 antibody (pembrolizumab) therapy at our hospital between August 2012 and July 2015 were retrospectively reviewed. Adverse events were evaluated according to the National Cancer Institute Common...περισσότερα »
Peripherally inserted central catheters (PICCs) in cancer patients under chemotherapy
: A prospective study on the incidence of complications and overall failures: Background and Objectives The increasing use of peripherally inserted central venous catheters (PICCs) for chemotherapy has led to the observation of an elevated risk of complications and failures. This study investigates PICC failures in cancer patients. Methods A prospective study was conducted at a single cancer institution on 291 PICC placement for chemotherapy. The primary study outcome was PICC failure. Results Median follow-up was 119 days. PICC complications occurred in 72 patients (24.7%) and fail... περισσότερα »
HPV Positive Head and Neck Cancers: Molecular Pathogenesis and Evolving Treatment Strategies
Cancers, Vol. 8, Pages 41: HPV Positive Head and Neck Cancers: Molecular Pathogenesis and Evolving Treatment Strategies: Head and neck squamous cell carcinoma (HNSCC) is a highly heterogeneous disease that is the result of tobacco and/or alcohol abuse or infection with high-risk Human papillomaviruses. Despite the fact that HPV positive HNSCC cancers form a distinct clinical entity with better treatment outcome, all HNSCC are currently treated uniformly with the same treatment modality. At present, biologic basis of these different outcomes and their therapeutic influence are areas ...περισσότερα »
Tp53/ p53 Status in Keratoacanthomas
Tp53/ p53 Status in Keratoacanthomas: Abstract Background Keratoacanthoma (KA) is a common keratinocytic skin neoplasm that typically develops rapidly and undergoes complete spontaneous regression. Since the pro-apoptotic p53 protein may be involved in the lifecycle of KA, we studied the p53 status throughout the main stages of KA that include proliferation, maturation and regression in a large series of lesions. Methods One-hundred and twenty four keratoacanthomas were characterized with respect to age of the lesions both clinically and histopathologically, in addition to phenotypi... περισσότερα »
Microtubules, polarity and vertebrate neural tube morphogenesis
Microtubules, polarity and vertebrate neural tube morphogenesis: Abstract Microtubules (MTs) are key cellular components, long known to participate in morphogenetic events that shape the developing embryo. However, the links between the cellular functions of MTs, their effects on cell shape and polarity, and their role in large-scale morphogenesis remain poorly understood. Here, these relationships were examined with respect to two strategies for generating the vertebrate neural tube: bending and closure of the mammalian neural plate; and cavitation of the teleost neural rod. The l... περισσότερα »
Eosinophilic Drug Allergy
Eosinophilic Drug Allergy: AbstractWhile peripheral or tissue eosinophilia may certainly characterize drug eruptions, this feature is hardly pathognomonic for a medication-induced etiology. While delayed drug hypersensitivity reactions with prominent eosinophilic recruitment have been typically classified as type IVb reactions, their pathophysiology is now known to be more complex. Eosinophilic drug reactions have a diversity of presentations and may be benign and self-limited to severe and life-threatening. The extent of clinical involvement is also heterogeneous, ranging from iso... περισσότερα »
Eosinophilic Skin Diseases: A Comprehensive Review
Eosinophilic Skin Diseases: A Comprehensive Review: AbstractEosinophilic skin diseases, commonly termed as eosinophilic dermatoses, refer to a broad spectrum of skin diseases characterized by eosinophil infiltration and/or degranulation in skin lesions, with or without blood eosinophilia. The majority of eosinophilic dermatoses lie in the allergy-related group, including allergic drug eruption, urticaria, allergic contact dermatitis, atopic dermatitis, and eczema. Parasitic infestations, arthropod bites, and autoimmune blistering skin diseases such as bullous pemphigoid, are also c...περισσότερα »
How to diagnose mould allergy? Comparison of skin prick tests with specific IgE results
How to diagnose mould allergy? Comparison of skin prick tests with specific IgE results: Abstract Background Diagnosis of mould allergy is complicated due to the heterogeneity of the test material and the decrease in the number of commercial mould skin test solutions that are currently available. Objectives The aim of the present study was to compare skin prick tests (SPT) from different manufacturers to one another and concurrently with sIgE tests for *Aspergillus fumigatus* (Asp f)*, Cladosporium herbarum* (Cla h)*, Penicillium chrysogenum* (Pen ch)*, Alternaria alternata* (Alt a)... περισσότερα »
Breastfeeding, bottle feeding and risk of malocclusion
in mixed and permanent dentitions: a systematic review via Brazilian Oral Research Abstract The aim of the present study was to search for scientific evidence concerning the association between breastfeeding and bottle feeding and risk of malocclusion in mixed and permanent dentitions. An electronic search was performed in eight databases up to February 2015. Additionally, a gray literature search and hand searches of the reference lists of the selected studies were also carried out. There were no restrictions on language or on year of publication. The methodology of the included ar... περισσότερα »
Vinyl polysiloxane
Influence of different fillers on the properties of an experimental vinyl polysiloxane via Brazilian Oral Research Abstract The aim of the study was to evaluate the effect of the incorporation of different fillers on an experimental vinyl polysiloxane (VPS) at two different concentrations, 20% and 40%. Different fillers were added to an experimental VPS. The study was developed in two stages: (i) incorporation of fillers in different concentrations: (a) 20 wt% fillers, and (b) 40 wt%. The fillers were added to experimental VPS and mixed with a speed mixer; (ii) characterization of ex... περισσότερα »
Macroscopic technique for the evaluation of oral tongue tumour thickness
: a reliable intraoperative method via Oral and Maxillofacial Surgery Publication date: Available online 28 March 2016 *Source:*International Journal of Oral and Maxillofacial Surgery Author(s): M. Pandey, S. Vidhyadharan, U. Puthalath, R. Veeraraghavan, S.V. Sukumaran, C. Prasad, S. Iyer, K. Thankappan There is no reliable method to assess tumour thickness preoperatively or intraoperatively in cases of oral tongue squamous cell carcinoma (SCC). The purpose of this study was to evaluate the efficacy of a macroscopic technique to measure tumour thickness. This was a prospective study of... περισσότερα »
Correlation of Lymph Node Density with Negative Outcome Predictors in Oral and Maxillofacial Squamous Cell Carcinoma
Correlation of Lymph Node Density with Negative Outcome Predictors in Oral and Maxillofacial Squamous Cell Carcinoma via Oral and Maxillofacial Surgery Publication date: Available online 28 March 2016 *Source:*Journal of Oral and Maxillofacial Surgery Author(s): Roderick Youngdo Kim, Brent Benson Ward, Hans C. Brockhoff, Joseph I. Helman, Thomas M. Braun, Christos A. Skouteris PurposeLymph node density is defined as the number of positive lymph nodes per total number of excised lymph nodes. In oral and maxillofacial cancer, there are recent data showing that increased lymph node density... περισσότερα »
Magnetic Resonance Imaging of Temporomandibular Joints of Children
Magnetic Resonance Imaging of Temporomandibular Joints of Children via Oral and Maxillofacial Surgery Publication date: Available online 28 March 2016 *Source:*Journal of Oral and Maxillofacial Surgery Author(s): Justine Moe, Nilesh Desai, Jian Kang, Shelly Abramowicz PurposeTo identify magnetic resonance imaging (MRI) findings of temporomandibular joints (TMJ) in healthy children.Materials and MethodsThis was a retrospective study of children younger than 18 years of age undergoing MRI of the head for non-autoimmune indications at Children’s Healthcare of Atlanta. Patients with congeni...περισσότερα »
Opioid overdose in a child: case report and discussion with emphasis on neurosurgical implications.
Related Articles *Opioid overdose in a child: case report and discussion with emphasis on neurosurgical implications.* J Neurosurg Pediatr. 2015 Dec;16(6):752-7 Authors: Reisner A, Hayes LL, Holland CM, Wrubel DM, Kebriaei MA, Geller RJ, Baum GR, Chern JJ Abstract In environments in which opioids are increasingly abused for recreation, children are becoming more at risk for both accidental and nonaccidental intoxication. In toxic doses, opioids can cause potentially lethal acute leukoencephalopathy, which has a predilection for the cerebellum in young children. The authors prese... περισσότερα »
Oral tongue tumour thickness
Macroscopic technique for the evaluation of oral tongue tumour thickness: a reliable intraoperative method: There is no reliable method to assess tumour thickness preoperatively or intraoperatively in cases of oral tongue squamous cell carcinoma (SCC). The purpose of this study was to evaluate the efficacy of a macroscopic technique to measure tumour thickness. This was a prospective study of 51 consecutive patients with T1/T2 primary SCC of the oral tongue. All patients underwent primary resection with ipsilateral neck dissection. Thickness measurements were obtained using Vernier ...περισσότερα »
Unusual Case of Sinusitis Related to Ectopic Teeth in the Maxillary Sinus Roof/Orbital Floor: A Report
Unusual Case of Sinusitis Related to Ectopic Teeth in the Maxillary Sinus Roof/Orbital Floor: A Report: Cranial Maxillofac Trauma Reconstruction DOI: 10.1055/s-0036-1581063 This article presents a case report of an adult patient with chronic sinusitis related to the presence of two erupted ectopic teeth located atypically in the maxillary sinus roof/orbital floor after a long latency period associated with childhood facial trauma. This article aims to show the treatment of chronic sinusitis of odontogenic origin by surgical removal of ectopic teeth in an unusual position by direct ... περισσότερα »
Anesthetic Complication during Maxillofacial Trauma Surgery
: A Case Report of Intraoperative Tension Pneumothorax: Cranial Maxillofac Trauma Reconstruction DOI: 10.1055/s-0036-1572504 Tension pneumothorax is a life-threatening emergency that requires a high index of suspension and immediate intervention to prevent circulatory collapse and death. Only five cases of pneumothorax were described in the Oral and Maxillofacial Surgery literature. All cases were postoperative complications associated with orthognathic surgery. We report a case of intraoperative tension pneumothorax during a routine facial trauma surgery requiring emergency chest ...περισσότερα »
Fw: Ammonium ceric nitrate and Neodymium oxide
Alexandros G. SfakianakisστοOnline Medical Journals by Alexandros G.SfakianakisΠριν από 34 δευτερόλεπτα
Dear Sir, Hi ! It is glad to inform you that we have lanched *Ammonium ceric nitrate , Neodymium oxide , Lanthanum oxide* ,which with acceptable price、high purity . Attached with Ammonium ceric nitrate and Neodymium oxide for your reference and pls have a try in your market if possible. Best regards. Seven 2016-03-28 ------------------------------ Seven Website: www.gzwfen.com Ganzhou Wanfeng Advanced Materials Tech., Co., Ltd. Address*: *office 1706,Yunxing Century, No.8 , Ganjiangyuan Ave., Zhanggong District , Ganzhou , Jiangxi Province , China E-mail :seven@g... περισσότερα »
Traumatic Intraorbital Encephalocele: Long-Term Results of Orbital Roof Repair with Titanium Mesh
Long-Term Results of Orbital Roof Repair with Titanium Mesh in a Case of Traumatic Intraorbital Encephalocele: A Case Report and Review of Literature: Cranial Maxillofac Trauma Reconstruction DOI: 10.1055/s-0036-1581064 Orbital roof fractures associated with cranial and maxillofacial trauma are rarely encountered. Traumatic intraorbital encephaloceles due to orbital roof fractures developing in the early posttraumatic period are even rarer. A variety of materials, such as alloplastic implants or autogenous materials, have been used for the reconstruction of orbital roof, but data ... περισσότερα »
Patient-Specific Implant for Residual Facial Asymmetry following Orthognathic Surgery in Unilateral Craniofacial Microsomia
Patient-Specific Implant for Residual Facial Asymmetry following Orthognathic Surgery in Unilateral Craniofacial Microsomia: Cranial Maxillofac Trauma Reconstruction DOI: 10.1055/s-0036-1581061 Craniofacial microsomia (CFM) is a congenital anomaly with a variable phenotype. The most prominent feature of CFM is a predominantly unilateral hypoplasia of the mandible, leading to facial asymmetry. Even after correction of the midline, there is often a remaining hard- and soft-tissue deficiency over the body of the mandible and cheek on the affected side. This clinical report describes ...περισσότερα »
Programmable RNA Tracking in Live Cells with CRISPR/Cas9
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 36 δευτερόλεπτα
Publication date: Available online 17 March 2016 Source:Cell Author(s): David A. Nelles, Mark Y. Fang, Mitchell R. O’Connell, Jia L. Xu, Sebastian J. Markmiller, Jennifer A. Doudna, Gene W. Yeo RNA-programmed genome editing using CRISPR/Cas9 from Streptococcus pyogenes has enabled rapid and accessible alteration of specific genomic loci in many organisms. A flexible means to […]
The Nuclear Pore Complex as a Flexible and Dynamic Gate
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 36 δευτερόλεπτα
Publication date: 10 March 2016 Source:Cell, Volume 164, Issue 6 Author(s): Kevin E. Knockenhauer, Thomas U. Schwartz Nuclear pore complexes (NPCs) perforate the nuclear envelope and serve as the primary transport gates for molecular exchange between nucleus and cytoplasm. Stripping the megadalton complex down to its most essential organizational elements, one can divide the NPC […]
Finding Hidden Motives
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 36 δευτερόλεπτα
Publication date: 24 March 2016 Source:Cell, Volume 165, Issue 1 from #ORL-AlexandrosSfakianakis via simeraentaxei on Inoreader http://ift.tt/22KeJC2 via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
Staying Afloat in the Rising Tide of Science
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 36 δευτερόλεπτα
Publication date: 10 March 2016 Source:Cell, Volume 164, Issue 6 Author(s): Carl Zimmer New York Times columnist and science writer Carl Zimmer discusses the challenges of effectively communicating with the public about science. Teaser New York Times columnist and science writer Carl Zimmer discusses the challenges of effectively communicating with the public about science. from […]
Capturing the Value of Biomedical Research
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 36 δευτερόλεπτα
Publication date: 24 March 2016 Source:Cell, Volume 165, Issue 1 Author(s): Stefano Bertuzzi, Zeina Jamaleddine Assessing the real-world impact of biomedical research is notoriously difficult. Here, we present the framework for building a prospective science-centered information system from scratch that has been afforded by the Sidra Medical and Research Center in Qatar. This experiment is […]
A Small RNA-Catalytic Argonaute Pathway Tunes Germline Transcript Levels to Ensure Embryonic Divisions
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 36 δευτερόλεπτα
Publication date: Available online 24 March 2016 Source:Cell Author(s): Adina Gerson-Gurwitz, Shaohe Wang, Shashank Sathe, Rebecca Green, Gene W. Yeo, Karen Oegema, Arshad Desai Multiple division cycles without growth are a characteristic feature of early embryogenesis. The female germline loads proteins and RNAs into oocytes to support these divisions, which lack many quality control mechanisms […]
The Molecular Harbingers of Early Mammalian Embryo Patterning
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 36 δευτερόλεπτα
Publication date: 24 March 2016 Source:Cell, Volume 165, Issue 1 Author(s): Jun Wu, Juan Carlos Izpisua Belmonte Random or not, the mechanisms at play during the first cell-fate determination in mammalian embryos have been debated for years. Studies by Goolam et al. and White et al. shed new light on the molecular mechanisms underlying the […]
Lost Voices, Missed Connections
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 36 δευτερόλεπτα
Publication date: 10 March 2016 Source:Cell, Volume 164, Issue 6 from #ORL-AlexandrosSfakianakis via simeraentaxei on Inoreader http://ift.tt/22KeJSA via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
CASTORing New Light on Amino Acid Sensing
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 36 δευτερόλεπτα
Publication date: 24 March 2016 Source:Cell, Volume 165, Issue 1 Author(s): James E. Hughes Hallett, Brendan D. Manning The activation state of mTORC1, a master regulator of cell growth, is particularly sensitive to changes in the intracellular levels of the amino acid arginine, but the sensing mechanisms are poorly understood. In this issue of Cell, […]
The 3D Genome as Moderator of Chromosomal Communication
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 36 δευτερόλεπτα
Publication date: 10 March 2016 Source:Cell, Volume 164, Issue 6 Author(s): Job Dekker, Leonid Mirny Proper expression of genes requires communication with their regulatory elements that can be located elsewhere along the chromosome. The physics of chromatin fibers imposes a range of constraints on such communication. The molecular and biophysical mechanisms by which chromosomal communication […]
Array Pattern Synthesis Using Particle Swarm Optimization with Dynamic Inertia Weight
A Feedback Particle Swarm Optimization (FPSO) with a family of fitness functions is proposed to minimize sidelobe level (SLL) and control null. In order to search in a large initial space and converge fast in local space to a refined solution, a FPSO with nonlinear inertia weight algorithm is developed, which is determined by a… Continue reading Array Pattern Synthesis Using Particle Swarm Optimization with Dynamic Inertia Weight
Accuracy of Intraocular Lens Power Calculation Formulas for Highly Myopic Eyes
Purpose. To evaluate and compare the accuracy of different intraocular lens (IOL) power calculation formulas for eyes with an axial length (AL) greater than 26.00 mm. Methods. This study reviewed 407 eyes of 219 patients with AL longer than 26.0 mm. The refractive prediction errors of IOL power calculation formulas (SRK/T, Haigis, Holladay, Hoffer Q, and Barrett… Continue reading Accuracy of Intraocular Lens Power Calculation Formulas for Highly Myopic Eyes
An Adverse Reaction in the Pediatric Sleep Laboratory
We present a case of a 15-month-old boy with Cornelia de Lange Syndrome (NIPBL gene mutation). On a PSG, central sleep apnea (central apnea-hypopnea index of 19/hour) and nocturnal hypoventilation (transcutaneous CO2 > 50 mmHg for 53% of the night) were found. A positive pressure initiation study was aborted because the patient developed a serious adverse… Continue reading An Adverse Reaction in the Pediatric Sleep Laboratory
Characterization of Clostridium difficile Strains in British Columbia, Canada: A Shift from NAP1 Majority (2008) to Novel Strain Types (2013) in One Region
Background. Clostridium difficile is a major cause of gastrointestinal illness. Epidemic NAP1 strains contain toxins A and B, a deletion in repressor tcdC, and a binary toxin. Objectives. To determine the molecular epidemiology of C. difficile in British Columbia and compare between two time points in one region. Methods. C. difficile isolates from hospital and… Continue reading Characterization of Clostridium difficile Strains in British Columbia, Canada: A Shift from NAP1 Majority (2008) to Novel Strain Types (2013) in One Region
Primary Nasal Tuberculosis in a 10-Year-Old Girl
Nasal tuberculosis is a rare clinical entity which mainly presents in elderly people. Nasal tuberculosis has always been considered to be secondary to tuberculosis of the lungs, and in rare instances it is a primary infection, usually when mycobacteria are inhaled. We describe the case of a 10-year-old girl who was successfully treated for primary… Continue reading Primary Nasal Tuberculosis in a 10-Year-Old Girl
Acupoints Stimulation for Anxiety and Depression in Cancer Patients: A Quantitative Synthesis of Randomized Controlled Trials
This study aims at concluding the current evidence on the therapeutic effects of acupoints stimulation for cancer patients with anxiety and depression. Randomized controlled trials using acupoints stimulation for relieving anxiety and/or depression in cancer patients were searched, and 11 studies were finally included, of which eight trials compared acupoints stimulation with standard methods of… Continue reading Acupoints Stimulation for Anxiety and Depression in Cancer Patients: A Quantitative Synthesis of Randomized Controlled Trials
Effects of Lung Expansion Therapy on Lung Function in Patients with Prolonged Mechanical Ventilation
Common complications in PMV include changes in the airway clearance mechanism, pulmonary function, and respiratory muscle strength, as well as chest radiological changes such as atelectasis. Lung expansion therapy which includes IPPB and PEEP prevents and treats pulmonary atelectasis and improves lung compliance. Our study presented that patients with PMV have improvements in lung volume… Continue reading Effects of Lung Expansion Therapy on Lung Function in Patients with Prolonged Mechanical Ventilation
Iterative MIMO Detection and Channel Estimation Using Joint Superimposed and Pilot-Aided Training
This paper presents a novel iterative detection and channel estimation scheme that combines the effort of superimposed training (ST) and pilot-aided training (PAT) for multiple-input multiple-output (MIMO) flat fading channels. The proposed method, hereafter known as joint mean removal ST and PAT (MRST-PAT), implements an iterative detection and channel estimation that achieves the performance of… Continue reading Iterative MIMO Detection and Channel Estimation Using Joint Superimposed and Pilot-Aided Training
A Novel Blind Source Separation Algorithm and Performance Analysis of Weak Signal against Strong Interference in Passive Radar Systems
In Passive Radar System, obtaining the mixed weak object signal against the super power signal (jamming) is still a challenging task. In this paper, a novel framework based on Passive Radar System is designed for weak object signal separation. Firstly, we propose an Interference Cancellation algorithm (IC-algorithm) to extract the mixed weak object signals from… Continue reading A Novel Blind Source Separation Algorithm and Performance Analysis of Weak Signal against Strong Interference in Passive Radar Systems
Highway Expenditures and Associated Customer Satisfaction: A Case Study
This study analyzes the satisfaction of the Nevadans with respect to their highway transportation system and the corresponding expenditures of Nevada Department of Transportation (NDOT). A survey questionnaire was designed to capture the opinions of the Nevadans (customers) about a number of characteristics of their transportation system. Data from the financial data warehouse of the… Continue reading Highway Expenditures and Associated Customer Satisfaction: A Case Study
Distributed acoustic cues for caller identity in macaque vocalization.
*Distributed acoustic cues for caller identity in macaque vocalization.* R Soc Open Sci. 2015 Dec;2(12):150432 Authors: Fukushima M, Doyle AM, Mullarkey MP, Mishkin M, Averbeck BB Abstract Individual primates can be identified by the sound of their voice. Macaques have demonstrated an ability to discern conspecific identity from a harmonically structured 'coo' call. Voice recognition presumably requires the integrated perception of multiple acoustic features. However, it is unclear how this is achieved, given considerable variability across utterances. Specifically, the extent to ... περισσότερα »
When information does not suffice: young people living with HIV and communication about ART adherence in the clinic.
*When information does not suffice: young people living with HIV and communication about ART adherence in the clinic.* Vulnerable Child Youth Stud. 2016 Jan 2;11(1):60-68 Authors: Bernays S, Paparini S, Gibb D, Seeley J Abstract Despite mounting evidence recommending disclosure of human immunodeficiency virus (HIV) status to young people with perinatally acquired HIV as a central motivating factor for adherence to antiretroviral therapy, many young people continue to experience disclosure as a partial event, rather than a process. Drawing from two longitudinal, interview-based qua...περισσότερα »
Giving patients a voice when they need one most.
*Giving patients a voice when they need one most.* Hosp Health Netw. 2016 Feb;90(2):19 Authors: Arcuri L PMID: 27017816 [PubMed - in process] from Speech via xlomafota13 on Inoreader http://ift.tt/21QSZi0 via IFTTT
Research with and by people with learning disabilities.
*Research with and by people with learning disabilities.* Nurs Times. 2016 Feb 10-23;112(6-7):15-8 Authors: Durell S Abstract Many people with learning disabilities are frequently excluded from active involvement in research and, as a result, along with researchers, have questioned research processes. These discussions have influenced how research is undertaken by, and with, people who have learning disabilities. Learning disability research is now increasingly framed as inclusive. This article explores the development of inclusive learning disability research by tracing its back... περισσότερα »
Distributed acoustic cues for caller identity in macaque vocalization.
*Distributed acoustic cues for caller identity in macaque vocalization.* R Soc Open Sci. 2015 Dec;2(12):150432 Authors: Fukushima M, Doyle AM, Mullarkey MP, Mishkin M, Averbeck BB Abstract Individual primates can be identified by the sound of their voice. Macaques have demonstrated an ability to discern conspecific identity from a harmonically structured 'coo' call. Voice recognition presumably requires the integrated perception of multiple acoustic features. However, it is unclear how this is achieved, given considerable variability across utterances. Specifically, the extent to ... περισσότερα »
When information does not suffice: young people living with HIV and communication about ART adherence in the clinic.
*When information does not suffice: young people living with HIV and communication about ART adherence in the clinic.* Vulnerable Child Youth Stud. 2016 Jan 2;11(1):60-68 Authors: Bernays S, Paparini S, Gibb D, Seeley J Abstract Despite mounting evidence recommending disclosure of human immunodeficiency virus (HIV) status to young people with perinatally acquired HIV as a central motivating factor for adherence to antiretroviral therapy, many young people continue to experience disclosure as a partial event, rather than a process. Drawing from two longitudinal, interview-based qua...περισσότερα »
Giving patients a voice when they need one most.
*Giving patients a voice when they need one most.* Hosp Health Netw. 2016 Feb;90(2):19 Authors: Arcuri L PMID: 27017816 [PubMed - in process] from Speech via xlomafota13 on Inoreader http://ift.tt/21QSZi0
Research with and by people with learning disabilities.
*Research with and by people with learning disabilities.* Nurs Times. 2016 Feb 10-23;112(6-7):15-8 Authors: Durell S Abstract Many people with learning disabilities are frequently excluded from active involvement in research and, as a result, along with researchers, have questioned research processes. These discussions have influenced how research is undertaken by, and with, people who have learning disabilities. Learning disability research is now increasingly framed as inclusive. This article explores the development of inclusive learning disability research by tracing its back... περισσότερα »
Admission, management and outcomes of acute pancreatitis in intensive care
ANZ Journal of Surgery from Emergency Medicine via xlomafota13 on Inoreader http://ift.tt/1oj1oxG
Postpartum 2D and 3D ultrasound evaluation of the anal sphincter complex in women with obstetric anal sphincter injuries
Ultrasound in Obstetrics & Gynecology from Emergency Medicine via xlomafota13 on Inoreader http://ift.tt/1VRfN1x
Acute phase of aortic dissection: a pilot study on CD40L, MPO, and MMP-1, -2, 9 and TIMP-1 circulating levels in elderly patients
Immunity & Ageing from Emergency Medicine via xlomafota13 on Inoreader http://ift.tt/1oj1m8U
High serum adiponectin levels predict incident falls among middle-aged and older adults: a prospective cohort study
Age and Aging from Emergency Medicine via xlomafota13 on Inoreader http://ift.tt/1VRfMLf
64-year-old-woman with chest pressure and shortness of breath
Mayo Clinic Proceedings from Emergency Medicine via xlomafota13 on Inoreader http://ift.tt/1oj1oxB
Surgery or stenting for colonic obstruction: A practice management guideline from the Eastern Association for the Surgery of Trauma
The Journal of Trauma and Acute Care Surgery from Emergency Medicine via xlomafota13 on Inoreader http://ift.tt/1VRfKmB
Research and evaluations of the health aspects of disasters, part VII: the relief/recovery framework
Prehospital and Disaster Medicine from Emergency Medicine via xlomafota13 on Inoreader http://ift.tt/1oj1oxz
Comparative analysis of liver injury-associated cytokines in acute hepatitis A and B
Yonsei Medical Journal from Emergency Medicine via xlomafota13 on Inoreader http://ift.tt/1VRfKmx
Flourishing and posttraumatic growth. an empirical take on ancient wisdoms
Health Care Analysis from Emergency Medicine via xlomafota13 on Inoreader http://ift.tt/1oj1oxv
Trends in treatment of infectious parapneumonic effusions in U.S. childrens hospitals, 2004-2014
Journal of Pediatric Surgery from Emergency Medicine via xlomafota13 on Inoreader http://ift.tt/1VRfKmt
A systematic review of the prevalence of oropharyngeal dysphagia in stroke, Parkinson’s disease, Alzheimer’s disease, head injury, and pneumonia
Dysphagia from Emergency Medicine via xlomafota13 on Inoreader http://ift.tt/1oj1lSs
Mental health risk factors in sexual assault: What should Sexual Assault Referral Centre staff be aware of?
Journal of Forensic and Legal Medicine from Emergency Medicine via xlomafota13 on Inoreader http://ift.tt/1VRfKmp
Understanding an inclusive trauma system through characterization of admissions at level IV centers
The American Journal of Surgery from Emergency Medicine via xlomafota13 on Inoreader http://ift.tt/1oj1oh6
Outcomes before and after the implementation of a critical pathway for patients with acute aortic disease
Yonsei Medical Journal from Emergency Medicine via xlomafota13 on Inoreader http://ift.tt/1VRfJPt
Risk factors for venous thromboembolism after acute trauma: A population-based case-cohort study
Thrombosis Research from Emergency Medicine via xlomafota13 on Inoreader http://ift.tt/1oj1oh2
Risk factors for clavicle fracture concurrent with brachial plexus injury
Archives of Gynecology and Obstetrics from Emergency Medicine via xlomafota13 on Inoreader http://ift.tt/1VRfJPl
The applicability of Trauma and Injury Severity Score for a blunt trauma population in Korea and a proposal of new models using score predictors
Yonsei Medical Journal from Emergency Medicine via xlomafota13 on Inoreader http://ift.tt/1oj1lBV
Joint dislocations in the pediatric emergency department
Clinical Pediatric Emergency Medicine from Emergency Medicine via xlomafota13 on Inoreader http://ift.tt/1VRfJPj
Incidence of acute postoperative endophthalmitis after cataract surgery
Ophthalmology from Emergency Medicine via xlomafota13 on Inoreader http://ift.tt/1oj1lBR
Factors associated with amputation following popliteal vascular injuries
Annals of Vascular Surgery from Emergency Medicine via xlomafota13 on Inoreader http://ift.tt/1VRfK63
Emergency Department Management of Heart Failure and COPD: A National Survey of Attitudes and Practice
Research Articles Michael K.P. Hale, Ian G. Stiell, Catherine M. Clement Canadian Journal of Emergency Medicine,FirstView Article(s), 8 pages Abstract [image: Facebook][image: Twitter][image: Mendeley][image: Email][image: More...] from Emergency Medicine via xlomafota13 on Inoreader http://ift.tt/1Tg4oI8
Emergency point-of-care ultrasound in Canadian pediatric emergency fellowship programs: current integration and future directions
Research Articles Julia Hoeffe, Marie Pier Desjardins, Jason Fischer, Benoit Carriere, Jocelyn Gravel Canadian Journal of Emergency Medicine,FirstView Article(s), 6 pages Abstract [image: Facebook][image: Twitter][image: Mendeley][image: Email][image: More...] from Emergency Medicine via xlomafota13 on Inoreader http://ift.tt/1MPjZHM
Cardiac myxoma in pregnancy: a comprehensive review.
[image: http:--http://ift.tt/1Fkw4zC] Related Articles *Cardiac myxoma in pregnancy: a comprehensive review.* Rev Bras Cir Cardiovasc. 2015 Jul-Sep;30(3):386-94 Authors: Yuan SM Abstract OBJECTIVE: Cardiac myxoma in pregnancy is rare and the clinical characteristics of this entity have been insufficiently elucidated. This article aims to describe the treatment options and the risk factors responsible for the maternal and feto-neonatal prognoses. METHODS: A comprehensive search of the literature of cardiac myxoma in pregnancy was conducted and 44 articles with 51 patients were incl... περισσότερα »
Mycobacterial spindle cell pseudotumour of the brain in a patient with sarcoidosis.
[image: http:--highwire.stanford.edu-icons-exter] Related Articles *Mycobacterial spindle cell pseudotumour of the brain in a patient with sarcoidosis.* BMJ Case Rep. 2015;2015 Authors: Ismail I, Carey M, Trotter S, Kunst H Abstract Mycobacterial spindle cell pseudotumours (MSP) are benign lesions characterised by local proliferation of spindle-shaped histiocytes caused by mycobacterial infections. Cerebral MSP due to Mycobacterium avium intracellulare (MAI) infection is rare, and is often misdiagnosed clinically and radiologically as a brain tumour. We present a case with under... περισσότερα »
Granulomatous Lymphoproliferative Disorders: Granulomatous Slack Skin and Lymphomatoid Granulomatosis.
[image: http:--linkinghub.elsevier.com-ihub-imag] [image: http:--http://ift.tt/1UuR80f] Related Articles *Granulomatous Lymphoproliferative Disorders: Granulomatous Slack Skin and Lymphomatoid Granulomatosis.* Dermatol Clin. 2015 Jul;33(3):489-96 Authors: Gangar P, Venkatarajan S Abstract Granulomatous cutaneous T-cell lymphomas (CTCL) and lymphomatoid granulomatosis are considered granulomatous lymphoproliferative disorders. The most common types of granulomatous CTCL are granulomatous mycosis fungoides and granulomatous slack skin. Lymphomatoid granulomatosis is a rare Epstein... περισσότερα »
Primary Epithelioid Angiosarcoma of Bone with Robust Cell Cycle Progression and High Expression of SPARC: A Case Report and Review of the Literature.
[image: http:--highwire.stanford.edu-icons-exter] Related Articles *Primary Epithelioid Angiosarcoma of Bone with Robust Cell Cycle Progression and High Expression of SPARC: A Case Report and Review of the Literature.* Ann Clin Lab Sci. 2015;45(3):360-5 Authors: Mauzo SH, Yang M, Brown RE, Nguyen HN, Yan P Abstract Epithelioid angiosarcoma of bone is a rare entity. Secreted protein acidic and rich in cysteine (SPARC), or osteonectin, is a secreted glycoprotein that has been implicated in tumorigenesis. We report a case of epithelioid angiosarcoma involving the long bones of the l... περισσότερα »
Ovarian Sertoli-Leydig Cell Tumor with Predominant Heterologous Mucinous Differentiation and Foci of Hepatocytic Differentiation: Case Report and Review of The Literature.
[image: http:--highwire.stanford.edu-icons-exter] Related Articles *Ovarian Sertoli-Leydig Cell Tumor with Predominant Heterologous Mucinous Differentiation and Foci of Hepatocytic Differentiation: Case Report and Review of The Literature.* Ann Clin Lab Sci. 2015;45(3):348-51 Authors: Liang L, Menzin A, Lovecchio JL, Navarro MD Abstract Sertoli-Leydig cell tumor is a rare ovarian neoplasm and belongs to the group of sex cord stromal tumors. We present a case of a 15-year old girl diagnosed with Sertoli-Leydig cell tumor with heterologous elements consisting predominantly of mucin... περισσότερα »
Epigenetic therapy overcomes treatment resistance in T cell prolymphocytic leukemia.
[image: http:--highwire.stanford.edu-icons-exter] [image: http:--http://ift.tt/1Fkw4zC] Related Articles *Epigenetic therapy overcomes treatment resistance in T cell prolymphocytic leukemia.* Sci Transl Med. 2015 Jun 24;7(293):293ra102 Authors: Hasanali ZS, Saroya BS, Stuart A, Shimko S, Evans J, Vinod Shah M, Sharma K, Leshchenko VV, Parekh S, Loughran TP, Epner EM Abstract T cell prolymphocytic leukemia (T-PLL) is a rare, mature T cell neoplasm with distinct features and an aggressive clinical course. Early relapse and short overall survival are commonplace. Use of the monoclon... περισσότερα »
Stroke of a cardiac myxoma origin.
[image: http:--http://ift.tt/1Fkw4zC] Related Articles *Stroke of a cardiac myxoma origin.* Rev Bras Cir Cardiovasc. 2015 Mar-Apr;30(2):225-34 Authors: Yuan SM, Humuruola G Abstract OBJECTIVE: The clinical features of cardiac myxoma stroke have not been sufficiently described. Debates remain concerning the options and timing of treatment and the clinical outcomes are unknown. This article aims to highlight the pertinent aspects of this rare condition. METHODS: Data source of the present study came from a comprehensive literature collection of cardiac myxoma stroke in PubMed, Googl... περισσότερα »
An imaging-guided platform for synergistic photodynamic/photothermal/chemo-therapy with pH/temperature-responsive drug release.
[image: http:--linkinghub.elsevier.com-ihub-imag] Related Articles *An imaging-guided platform for synergistic photodynamic/photothermal/chemo-therapy with pH/temperature-responsive drug release.* Biomaterials. 2015 Sep;63:115-27 Authors: Lv R, Yang P, He F, Gai S, Yang G, Dai Y, Hou Z, Lin J Abstract To integrate biological imaging and multimodal therapies into one platform for enhanced anti-cancer efficacy, we have designed a novel core/shell structured nano-theranostic by conjugating photosensitive Au25(SR)18 - (SR refers to thiolate) clusters, pH/temperature-responsive polyme... περισσότερα »
Long-Term Everolimus Treatment in Individuals With Tuberous Sclerosis Complex: A Review of the Current Literature.
[image: http:--linkinghub.elsevier.com-ihub-imag] Related Articles *Long-Term Everolimus Treatment in Individuals With Tuberous Sclerosis Complex: A Review of the Current Literature.* Pediatr Neurol. 2015 Jul;53(1):23-30 Authors: Tran LH, Zupanc ML Abstract BACKGROUND: Tuberous sclerosis complex is a genetic disease usually caused by mutations to either TSC1 or TSC2, where its gene products are involved in the inhibition of the mammalian target of rapamycin pathway. Under normal cellular conditions, mammalian target of rapamycin (mTOR) regulates cell growth and proliferation in r... περισσότερα »
Rare brainstem oligodendroglioma in an adult patient: Presentation, molecular characteristics and treatment response.
[image: http:--linkinghub.elsevier.com-ihub-imag] Related Articles *Rare brainstem oligodendroglioma in an adult patient: Presentation, molecular characteristics and treatment response.* J Neurol Sci. 2015 Aug 15;355(1-2):209-10 Authors: Hodges SD, Malafronte P, Gilhooly J, Skinner W, Carter C, Theeler BJ PMID: 26048048 [PubMed - indexed for MEDLINE] from #PubMed 3 via ola Kala on Inoreader http://ift.tt/1Sj4zNP via IFTTT
A rare case of a heavily calcified gastrointestinal stromal tumors with an intraluminal growth pattern.
[image: http:--http://ift.tt/1iA58YG] Related Articles *A rare case of a heavily calcified gastrointestinal stromal tumors with an intraluminal growth pattern.* Turk J Gastroenterol. 2015 May;26(3):277-8 Authors: Lai WJ, Xu YK PMID: 26006207 [PubMed - indexed for MEDLINE] from #PubMed 3 via ola Kala on Inoreader http://ift.tt/1My4uZX via IFTTT
Hemolymphangioma of the spleen: A report of a rare case.
[image: http:--http://ift.tt/1YyhL4R] [image: http:--http://ift.tt/1Fkw4zC] Related Articles *Hemolymphangioma of the spleen: A report of a rare case.* World J Gastroenterol. 2015 May 7;21(17):5442-4 Authors: Mei Y, Peng CJ, Chen L, Li XX, Li WN, Shu DJ, Xie WT Abstract Hemolymphangioma is a malformation of both lymphatic vessels and blood vessels. Splenic hemolymphangioma is extremely rare. Herein, we present a case of 62-year-old woman with ambiguous upper quadrant abdominal pain for two months who was found to have an occupying lesion in the spleen on computed tomography. She ... περισσότερα »
Improving recognition of hepatic perivascular epithelioid cell tumor: Case report and literature review.
[image: http:--http://ift.tt/1YyhL4R] [image: http:--http://ift.tt/1Fkw4zC] Related Articles *Improving recognition of hepatic perivascular epithelioid cell tumor: Case report and literature review.* World J Gastroenterol. 2015 May 7;21(17):5432-41 Authors: Maebayashi T, Abe K, Aizawa T, Sakaguchi M, Ishibashi N, Abe O, Takayama T, Nakayama H, Matsuoka S, Nirei K, Nakamura H, Ogawa M, Sugitani M Abstract A 58-year-old man presented with the chief complaint of abdominal bloating and was incidentally found to have a liver tumor. As diagnostic imaging studies could not rule out mali... περισσότερα »
Primary retroperitoneal mucinous cystadenoma: A case report.
[image: http:--http://ift.tt/1YyhL4R] [image: http:--http://ift.tt/1Fkw4zC] Related Articles *Primary retroperitoneal mucinous cystadenoma: A case report.* World J Gastroenterol. 2015 May 7;21(17):5427-31 Authors: Knezevic S, Ignjatovic I, Lukic S, Matic S, Dugalic V, Knezevic D, Micev M, Dragasevic S Abstract Primary retroperitoneal mucinous cystic tumors are extremely rare. These tumors can be classified as a primary retroperitoneal mucinous cystadenoma with or without borderline malignancy or primary retroperitoneal mucinous cystadenocarcinoma. The most common of these is prim... περισσότερα »
BAP1 mutation is a frequent somatic event in peritoneal malignant mesothelioma.
[image: http:--http://ift.tt/1NMOrDk] [image: http:--http://ift.tt/1Fkw4zC] Related Articles *BAP1 mutation is a frequent somatic event in peritoneal malignant mesothelioma.* J Transl Med. 2015;13:122 Authors: Alakus H, Yost SE, Woo B, French R, Lin GY, Jepsen K, Frazer KA, Lowy AM, Harismendy O Abstract BACKGROUND: Malignant mesothelioma (MM) arises from mesothelial cells that line the pleural, peritoneal and pericardial surfaces. The majority of MMs are pleural and have been associated with asbestos exposure. Previously, pleural MMs have been genetically characterized by the l... περισσότερα »
Primary intracranial low-grade fibromyxoid sarcoma with FUS gene rearrangement.
[image: http:--media.wiley.com-assets-7315-19-Wi] Related Articles *Primary intracranial low-grade fibromyxoid sarcoma with FUS gene rearrangement.* Neuropathology. 2015 Aug;35(4):348-53 Authors: Chen N, Gong J, Nie L, Chen X, Xu M, Chen M, Zhou Q Abstract Low-grade fibromyxoid sarcoma (LGFMS) is a rare sarcoma typically presenting as a deep soft tissue mass in the lower extremities or trunk. Only four cases of primary intracranial LGFMS have been reported in the literature, but none with molecular/cytogenetic data. We report here a new bona fide case confirmed by the characteris... περισσότερα »
Lack of IDH1 mutation in astroblastomas suggests putative origin from ependymoglial cells?
[image: http:--media.wiley.com-assets-7315-19-Wi] Related Articles *Lack of IDH1 mutation in astroblastomas suggests putative origin from ependymoglial cells?* Neuropathology. 2015 Aug;35(4):303-11 Authors: Asha U, Mahadevan A, Sathiyabama D, Ravindra T, Sagar BK, Bhat DI, Aravinda HR, Pandey P, Vilanilam GC Abstract Astroblastomas are extremely rare neuroepithelial tumors of uncertain histogenesis, affecting children and young adults, and constitute a new addition to the WHO 2000 classification of CNS tumors. We report the largest series of nine cases diagnosed in a single insti... περισσότερα »
In This Issue
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 43 δευτερόλεπτα
Publication date: 10 March 2016 Source:Cell, Volume 164, Issue 6 from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1MPmHwU via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
Genomic and Transcriptomic Features of Response to Anti-PD-1 Therapy in Metastatic Melanoma
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 43 δευτερόλεπτα
Publication date: 24 March 2016 Source:Cell, Volume 165, Issue 1 Author(s): Willy Hugo, Jesse M. Zaretsky, Lu Sun, Chunying Song, Blanca Homet Moreno, Siwen Hu-Lieskovan, Beata Berent-Maoz, Jia Pang, Bartosz Chmielowski, Grace Cherry, Elizabeth Seja, Shirley Lomeli, Xiangju Kong, Mark C. Kelley, Jeffrey A. Sosman, Douglas B. Johnson, Antoni Ribas, Roger S. Lo PD-1 immune […]
When Biology Doesn’t Add Up
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 43 δευτερόλεπτα
Publication date: 10 March 2016 Source:Cell, Volume 164, Issue 6 Physical models are increasingly used to inform our understanding of biology. Where such models still run into limits was the question that Cell’s Robert Kruger posed to Julie Theriot, K.C. Huang, and Mark Goulian. Annotated excerpts from this conversation are presented below, and the full […]
Metastatic Latency and Immune Evasion through Autocrine Inhibition of WNT
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 43 δευτερόλεπτα
Publication date: 24 March 2016 Source:Cell, Volume 165, Issue 1 Author(s): Srinivas Malladi, Danilo G. Macalinao, Xin Jin, Lan He, Harihar Basnet, Yilong Zou, Elisa de Stanchina, Joan Massagué Metastasis frequently develops years after the removal of a primary tumor, from a minority of disseminated cancer cells that survived as latent entities through unknown mechanisms. […]
Communication in Drug Development: “Translating” Scientific Discovery
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 43 δευτερόλεπτα
Publication date: 10 March 2016 Source:Cell, Volume 164, Issue 6 Author(s): Jeff Settleman, Robert L. Cohen The discovery and development of new medicines that promote human health and potentially extend natural life remains a remarkably challenging endeavor. In this Commentary, we identify key elements of communication required to successfully translate promising biological findings to novel […]
Programmable RNA Tracking in Live Cells with CRISPR/Cas9
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 43 δευτερόλεπτα
Publication date: Available online 17 March 2016 Source:Cell Author(s): David A. Nelles, Mark Y. Fang, Mitchell R. O’Connell, Jia L. Xu, Sebastian J. Markmiller, Jennifer A. Doudna, Gene W. Yeo RNA-programmed genome editing using CRISPR/Cas9 from Streptococcus pyogenes has enabled rapid and accessible alteration of specific genomic loci in many organisms. A flexible means to […]
The Nuclear Pore Complex as a Flexible and Dynamic Gate
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 43 δευτερόλεπτα
Publication date: 10 March 2016 Source:Cell, Volume 164, Issue 6 Author(s): Kevin E. Knockenhauer, Thomas U. Schwartz Nuclear pore complexes (NPCs) perforate the nuclear envelope and serve as the primary transport gates for molecular exchange between nucleus and cytoplasm. Stripping the megadalton complex down to its most essential organizational elements, one can divide the NPC […]
Finding Hidden Motives
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 43 δευτερόλεπτα
Publication date: 24 March 2016 Source:Cell, Volume 165, Issue 1 from #AlexandrosSfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/22KeJC2 via IFTTT
Staying Afloat in the Rising Tide of Science
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 43 δευτερόλεπτα
Publication date: 10 March 2016 Source:Cell, Volume 164, Issue 6 Author(s): Carl Zimmer New York Times columnist and science writer Carl Zimmer discusses the challenges of effectively communicating with the public about science. Teaser New York Times columnist and science writer Carl Zimmer discusses the challenges of effectively communicating with the public about science. from […]
Capturing the Value of Biomedical Research
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 43 δευτερόλεπτα
Publication date: 24 March 2016 Source:Cell, Volume 165, Issue 1 Author(s): Stefano Bertuzzi, Zeina Jamaleddine Assessing the real-world impact of biomedical research is notoriously difficult. Here, we present the framework for building a prospective science-centered information system from scratch that has been afforded by the Sidra Medical and Research Center in Qatar. This experiment is […]
A Small RNA-Catalytic Argonaute Pathway Tunes Germline Transcript Levels to Ensure Embryonic Divisions
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 43 δευτερόλεπτα
Publication date: Available online 24 March 2016 Source:Cell Author(s): Adina Gerson-Gurwitz, Shaohe Wang, Shashank Sathe, Rebecca Green, Gene W. Yeo, Karen Oegema, Arshad Desai Multiple division cycles without growth are a characteristic feature of early embryogenesis. The female germline loads proteins and RNAs into oocytes to support these divisions, which lack many quality control mechanisms […]
The Molecular Harbingers of Early Mammalian Embryo Patterning
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 43 δευτερόλεπτα
Publication date: 24 March 2016 Source:Cell, Volume 165, Issue 1 Author(s): Jun Wu, Juan Carlos Izpisua Belmonte Random or not, the mechanisms at play during the first cell-fate determination in mammalian embryos have been debated for years. Studies by Goolam et al. and White et al. shed new light on the molecular mechanisms underlying the […]
Lost Voices, Missed Connections
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 43 δευτερόλεπτα
Publication date: 10 March 2016 Source:Cell, Volume 164, Issue 6 from #AlexandrosSfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/22KeJSA via IFTTT
CASTORing New Light on Amino Acid Sensing
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 43 δευτερόλεπτα
Publication date: 24 March 2016 Source:Cell, Volume 165, Issue 1 Author(s): James E. Hughes Hallett, Brendan D. Manning The activation state of mTORC1, a master regulator of cell growth, is particularly sensitive to changes in the intracellular levels of the amino acid arginine, but the sensing mechanisms are poorly understood. In this issue of Cell, […]
The 3D Genome as Moderator of Chromosomal Communication
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 43 δευτερόλεπτα
Publication date: 10 March 2016 Source:Cell, Volume 164, Issue 6 Author(s): Job Dekker, Leonid Mirny Proper expression of genes requires communication with their regulatory elements that can be located elsewhere along the chromosome. The physics of chromatin fibers imposes a range of constraints on such communication. The molecular and biophysical mechanisms by which chromosomal communication […]
Content analysis of the professional journal of the College of Speech Therapists II: coming of age and growing maturity, 1946-65.
*Content analysis of the professional journal of the College of Speech Therapists II: coming of age and growing maturity, 1946-65.* Int J Lang Commun Disord. 2016 Mar 27; Authors: Stansfield J, Armstrong L Abstract BACKGROUND: Following a content analysis of the first 10 years of the UK professional journal Speech, this study was conducted to survey the published work of the speech (and language) therapy profession in the 20 years following the unification of two separate professional bodies into the College of Speech Therapists. AIM: To understand better the development of the sp...περισσότερα »
Hormonal changes following a low-salt diet in patients with Ménière's disease
Hormonal changes following a low-salt diet in patients with Ménière's disease via Auris Nasus Larynx Publication date: Available online 28 March 2016 *Source:*Auris Nasus Larynx Author(s): Takenori Miyashita, Ryuhei Inamoto, Shinjiro Fukuda, Hiroshi Hoshikawa, Hirofumi Hitomi, Hideyasu Kiyomoto, Akira Nishiyama, Nozomu Mori ObjectiveA low-salt diet has been the main treatment modality for Ménière's disease (MD) since the 1930s, although the mechanisms behind this therapy have not yet been elucidated. Salt reduction is associated with a physiological increase in plasma aldosterone conce... περισσότερα »
The missing vitamin alphabet
The missing vitamin alphabet: Abstract Aim The aims of this paper were to catalogue a complete list of all the alphabetical names for vitamins that have appeared in the scientific literature, provide the citations of their first use and seek explanations for any apparent gaps in the naming system. Methods The names of known vitamins and pseudo-vitamins were identified from standard nutrition textbooks, historical monographs and several review articles. If the first citation for the alphabetical vitamin name was not found in these sources, additional searches were conducted in the Sc... περισσότερα »
Food allergy in schools: The importance of government involvement
Food allergy in schools: The importance of government involvement: Abstract Aim Children have the highest rates of food-related allergic reactions. While 85% of children outgrow allergies including cow's milk and eggs by five years of age, allergies to peanuts and seafood continue into adulthood. The school setting poses a high-risk environment for allergen exposure. The aim of the present study was to examine the availability, drivers and communication of school food allergy awareness and management policies/guidelines in one Australian education jurisdiction. Methods A cross-secti...περισσότερα »
Nutritional management of cystic fibrosis and cystic fibrosis-related diabetes
in Australia: Abstract Aim The cystic fibrosis (CF) dietitians' role is to determine individualised nutritional management plans for patients. The aims of the present study were: to (i) document nutritional management delivered by Australian dietitians to patients with CF and CF-related diabetes (CFRD); (ii) examine if advice is consistent between CF centres within Australia; and (iii) determine if dietetic staffing is adequate for patient numbers. Methods A 25 question web-based survey was distributed via professional networks to dietitians working with adult patients with CF with... περισσότερα »
Association between dietary iron intake and bone mineral density
A cross-sectional study in Chinese population: [image: cover.gif?v=1&s=425e38c20b8df9993cee01a9] Abstract Aim The incidence of osteoporosis is rising continuously along with the ageing process in the Chinese population. Iron is an important trace element for bone growth, development and maintenance. However, the association of dietary iron with bone mineral density has not been widely investigated. The present study examined the cross-sectional association between dietary iron intake and phalangeal osteoporosis in the Chinese population. Methods A total of 1870 subjects were incl... περισσότερα »
Serum lipids and sudden sensorineural hearing loss
[image: http:--www.plosone.org-images-pone_120x3] [image: http:--www.ncbi.nlm.nih.gov-corehtml-pmc] Authors: Chang IJ, Kang CJ, Yueh CY, Fang KH, Yeh RM, Tsai YT Abstract BACKGROUND: Sudden sensorineural hearing loss (SSNHL) is a relatively common condition that is usually of unknown etiology. A number of individual studies have investigated the association between various serum lipids and SSNHL; however, the findings have been inconsistent. In an attempt to obtain more definitive information on the relationship between serum lipids and SSNHL, we carried out a systematic review an... περισσότερα »
Cancers, Vol. 8, Pages 41: HPV Positive Head and Neck Cancers: Molecular Pathogenesis and Evolving Treatment Strategies
Alexandros G. SfakianakisστοHead,Neck,Brain,Cervical Spine and Esophageal Cancers by Alexandros G. SfakianakisΠριν από 51 δευτερόλεπτα
Head and neck squamous cell carcinoma (HNSCC) is a highly heterogeneous disease that is the result of tobacco and/or alcohol abuse or infection with high-risk Human papillomaviruses. Despite the fact that HPV positive HNSCC cancers form a distinct clinical entity with better treatment outcome, all HNSCC are currently treated uniformly with the same treatment modality. At present, biologic basis of these different outcomes and their therapeutic influence are areas of intense investigation. In this review, we will summarize the molecular basis for this different outcome, novel treat... περισσότερα »
A rare presentation of multiple primary squamous cell carcinoma of the tongue in a patient with recurrent hepatitis C infection.
Alexandros G. SfakianakisστοHead,Neck,Brain,Cervical Spine and Esophageal Cancers by Alexandros G. SfakianakisΠριν από 51 δευτερόλεπτα
[image: http:--media.wiley.com-assets-7315-19-Wi] Related Articles *A rare presentation of multiple primary squamous cell carcinoma of the tongue in a patient with recurrent hepatitis C infection.* Spec Care Dentist. 2014 Mar-Apr;34(2):96-9 Authors: Stoopler ET, Sia YW, Chalian AA, O'Malley BW, Alawi F Abstract Hepatitis C virus (HCV) infection has been implicated as a risk factor for development of oral squamous cell carcinoma (SCC). Multiple primary sites of oral SCC associated with HCV infection occurs infrequently. This case report describes a rare presentation of multiple pri... περισσότερα »
EGJ outflow obstruction must be excluded in patients with high IRP and weak peristalsis.
[image: http:--http://ift.tt/1iA58YG] Related Articles *EGJ outflow obstruction must be excluded in patients with high IRP and weak peristalsis.* Turk J Gastroenterol. 2015 May;26(3):288 Authors: Sakin YS, Çelebi G, Kekilli M, Uygun A, Bağcı S PMID: 26006213 [PubMed - indexed for MEDLINE] from #ENT via xlomafota13 on Inoreader http://ift.tt/1VRePTd via IFTTT
The last innovation in achalasia treatment; per-oral endoscopic myotomy.
[image: http:--http://ift.tt/1iA58YG] Related Articles *The last innovation in achalasia treatment; per-oral endoscopic myotomy.* Turk J Gastroenterol. 2015 May;26(3):218-23 Authors: Aslan F, Akpınar Z, Alper E, Atay A, Yurtlu DA, Çekiç C, Bor S, Ünsal B Abstract BACKGROUND/AIMS: Per-oral endoscopic myotomy (POEM) is a minimally invasive endoscopic treatment option for patients with achalasia and has been performed since 2010. It is less invasive than Heller myotomy and its use is spreading rapidly worldwide. We present our results of POEM that, to the best of our knowledge, are ... περισσότερα »
[Proarrhythmic effects of domperidone in infants: a systematic review].
Related Articles *[Proarrhythmic effects of domperidone in infants: a systematic review].* Farm Hosp. 2014 Sep-Oct;38(5):438-44 Authors: Caraballo L, Molina G, Weitz D, Piskulic L, Avila A, Marzi M Abstract AIMS: To assess the association of the use of domperidone in infants with QTc interval prolongation and proarrhythmic events. METHODS: A systematic search of the scientific literature was conducted without any date or language restriction. The electronic database MEDLINE and the sources LILACS, ScIELO and Cochrane library were consulted. RESULTS: From the twelve identified studi... περισσότερα »
How to diagnose mould allergy? Comparison of skin prick tests with specific IgE results
Abstract Background Diagnosis of mould allergy is complicated due to the heterogeneity of the test material and the decrease in the number of commercial mould skin test solutions that are currently available. Objectives The aim of the present study was to compare skin prick tests (SPT) from different manufacturers to one another and concurrently with sIgE tests for *Aspergillus fumigatus* (Asp f)*, Cladosporium herbarum* (Cla h)*, Penicillium chrysogenum* (Pen ch)*, Alternaria alternata* (Alt a) and *Aspergillus versicolor* (Asp v) to ascertain a feasible diagnostic procedure for... περισσότερα »
Studies on the in vitro and in vivo degradation behavior of amino acid derivatives based organogels.
*Studies on the in vitro and in vivo degradation behavior of amino acid derivatives based organogels.* Drug Dev Ind Pharm. 2016 Mar 27;:1-31 Authors: Li Z, Cao J, Li H, Hu B, Liu H, Han F, Liu Z, Tong C, Li S Abstract The in vitro degradation behavior of organogel with different gelators based on amino acid was investigated in details. Two methods were applied in this research: weighting method and high performance liquid chromatography with evaporative light scattering detection (HPLC-ELSD) method, which was established for the first time. Their degradation behaviors in vivo wer... περισσότερα »
DESCENDING NECROTIZING MEDIASTINITIS SECONDARY TO RETROPHARYNGEAL ABSCESS.
*DESCENDING NECROTIZING MEDIASTINITIS SECONDARY TO RETROPHARYNGEAL ABSCESS.* Acta Clin Croat. 2015 Dec;54(4):541-6 Authors: Kovacić M, Kovacić I, Dželalija B Abstract Descending necrotizing mediastinitis secondary to a nontraumatic retropharyngeal abscess is very rare. This form of mediastinitis in the era of potent antibiotics often ends up with lethal outcome. It usually occurs in immunocompromised patients and requires intensive multidisciplinary treatment approach. We report a case of nontraumatic retropharyngeal abscess complicated by descending necrotizing mediastinitis in a... περισσότερα »
Thyroid Dysfunction in Children Exposed to Iodinated Contrast Media.
*Thyroid Dysfunction in Children Exposed to Iodinated Contrast Media.* J Clin Endocrinol Metab. 2016 Mar 28;:jc20161330 Authors: Barr ML, Chiu HK, Li N, Yeh MW, Rhee CM, Casillas J, Iskander PJ, Leung AM Abstract CONTEXT: Iodinated contrast media (ICM) is routinely used in imaging studies and contains several hundred-fold times the recommended daily allowance of iodine. OBJECTIVE: To determine whether children exposed to ICM have a higher risk of iodine-induced thyroid dysfunction. DESIGN: This was a single-institution case-control study, examining patients with incident thyroid d...περισσότερα »
Isolation of biologically active and morphologically intact exosomes from plasma of patients with cancer.
*Isolation of biologically active and morphologically intact exosomes from plasma of patients with cancer.* J Extracell Vesicles. 2016;5:29289 Authors: Hong CS, Funk S, Muller L, Boyiadzis M, Whiteside TL Abstract OBJECTIVE: Isolation from human plasma of exosomes that retain functional and morphological integrity for probing their protein, lipid and nucleic acid content is a priority for the future use of exosomes as biomarkers. A method that meets these criteria and can be scaled up for patient monitoring is thus desirable. METHODS: Plasma specimens (1 mL) of patients with acute...περισσότερα »
The impact of brain metastasis on quality of life, resource utilization and survival in patients with non-small-cell lung cancer.
*The impact of brain metastasis on quality of life, resource utilization and survival in patients with non-small-cell lung cancer.* Cancer Treat Rev. 2016 Mar 15;45:139-162 Authors: Peters S, Bexelius C, Munk V, Leighl N Abstract This systematic review aims to improve understanding of the burden of disease associated with brain metastases from non-small-cell lung cancer (NSCLC) in terms of survival, quality of life (QoL) and economic impact. PubMed/MEDLINE, Cochrane collaboration and EMBASE databases were searched for articles published in English from 2000 to 2014. Of 3288 abstra...περισσότερα »
Cardiac myxoma in pregnancy: a comprehensive review.
[image: http:--http://ift.tt/1Fkw4zC] Related Articles *Cardiac myxoma in pregnancy: a comprehensive review.* Rev Bras Cir Cardiovasc. 2015 Jul-Sep;30(3):386-94 Authors: Yuan SM Abstract OBJECTIVE: Cardiac myxoma in pregnancy is rare and the clinical characteristics of this entity have been insufficiently elucidated. This article aims to describe the treatment options and the risk factors responsible for the maternal and feto-neonatal prognoses. METHODS: A comprehensive search of the literature of cardiac myxoma in pregnancy was conducted and 44 articles with 51 patients were incl... περισσότερα »
Mycobacterial spindle cell pseudotumour of the brain in a patient with sarcoidosis.
[image: http:--highwire.stanford.edu-icons-exter] Related Articles *Mycobacterial spindle cell pseudotumour of the brain in a patient with sarcoidosis.* BMJ Case Rep. 2015;2015 Authors: Ismail I, Carey M, Trotter S, Kunst H Abstract Mycobacterial spindle cell pseudotumours (MSP) are benign lesions characterised by local proliferation of spindle-shaped histiocytes caused by mycobacterial infections. Cerebral MSP due to Mycobacterium avium intracellulare (MAI) infection is rare, and is often misdiagnosed clinically and radiologically as a brain tumour. We present a case with under... περισσότερα »
Granulomatous Lymphoproliferative Disorders: Granulomatous Slack Skin and Lymphomatoid Granulomatosis.
[image: http:--linkinghub.elsevier.com-ihub-imag] [image: http:--http://ift.tt/1UuR80f] Related Articles *Granulomatous Lymphoproliferative Disorders: Granulomatous Slack Skin and Lymphomatoid Granulomatosis.* Dermatol Clin. 2015 Jul;33(3):489-96 Authors: Gangar P, Venkatarajan S Abstract Granulomatous cutaneous T-cell lymphomas (CTCL) and lymphomatoid granulomatosis are considered granulomatous lymphoproliferative disorders. The most common types of granulomatous CTCL are granulomatous mycosis fungoides and granulomatous slack skin. Lymphomatoid granulomatosis is a rare Epstein... περισσότερα »
Primary Epithelioid Angiosarcoma of Bone with Robust Cell Cycle Progression and High Expression of SPARC: A Case Report and Review of the Literature.
[image: http:--highwire.stanford.edu-icons-exter] Related Articles *Primary Epithelioid Angiosarcoma of Bone with Robust Cell Cycle Progression and High Expression of SPARC: A Case Report and Review of the Literature.* Ann Clin Lab Sci. 2015;45(3):360-5 Authors: Mauzo SH, Yang M, Brown RE, Nguyen HN, Yan P Abstract Epithelioid angiosarcoma of bone is a rare entity. Secreted protein acidic and rich in cysteine (SPARC), or osteonectin, is a secreted glycoprotein that has been implicated in tumorigenesis. We report a case of epithelioid angiosarcoma involving the long bones of the l... περισσότερα »
Ovarian Sertoli-Leydig Cell Tumor with Predominant Heterologous Mucinous Differentiation and Foci of Hepatocytic Differentiation: Case Report and Review of The Literature.
[image: http:--highwire.stanford.edu-icons-exter] Related Articles *Ovarian Sertoli-Leydig Cell Tumor with Predominant Heterologous Mucinous Differentiation and Foci of Hepatocytic Differentiation: Case Report and Review of The Literature.* Ann Clin Lab Sci. 2015;45(3):348-51 Authors: Liang L, Menzin A, Lovecchio JL, Navarro MD Abstract Sertoli-Leydig cell tumor is a rare ovarian neoplasm and belongs to the group of sex cord stromal tumors. We present a case of a 15-year old girl diagnosed with Sertoli-Leydig cell tumor with heterologous elements consisting predominantly of mucin... περισσότερα »
Epigenetic therapy overcomes treatment resistance in T cell prolymphocytic leukemia.
[image: http:--highwire.stanford.edu-icons-exter] [image: http:--http://ift.tt/1Fkw4zC] Related Articles *Epigenetic therapy overcomes treatment resistance in T cell prolymphocytic leukemia.* Sci Transl Med. 2015 Jun 24;7(293):293ra102 Authors: Hasanali ZS, Saroya BS, Stuart A, Shimko S, Evans J, Vinod Shah M, Sharma K, Leshchenko VV, Parekh S, Loughran TP, Epner EM Abstract T cell prolymphocytic leukemia (T-PLL) is a rare, mature T cell neoplasm with distinct features and an aggressive clinical course. Early relapse and short overall survival are commonplace. Use of the monoclon... περισσότερα »
Stroke of a cardiac myxoma origin.
[image: http:--http://ift.tt/1Fkw4zC] Related Articles *Stroke of a cardiac myxoma origin.* Rev Bras Cir Cardiovasc. 2015 Mar-Apr;30(2):225-34 Authors: Yuan SM, Humuruola G Abstract OBJECTIVE: The clinical features of cardiac myxoma stroke have not been sufficiently described. Debates remain concerning the options and timing of treatment and the clinical outcomes are unknown. This article aims to highlight the pertinent aspects of this rare condition. METHODS: Data source of the present study came from a comprehensive literature collection of cardiac myxoma stroke in PubMed, Googl... περισσότερα »
An imaging-guided platform for synergistic photodynamic/photothermal/chemo-therapy with pH/temperature-responsive drug release.
[image: http:--linkinghub.elsevier.com-ihub-imag] Related Articles *An imaging-guided platform for synergistic photodynamic/photothermal/chemo-therapy with pH/temperature-responsive drug release.* Biomaterials. 2015 Sep;63:115-27 Authors: Lv R, Yang P, He F, Gai S, Yang G, Dai Y, Hou Z, Lin J Abstract To integrate biological imaging and multimodal therapies into one platform for enhanced anti-cancer efficacy, we have designed a novel core/shell structured nano-theranostic by conjugating photosensitive Au25(SR)18 - (SR refers to thiolate) clusters, pH/temperature-responsive polyme... περισσότερα »
Long-Term Everolimus Treatment in Individuals With Tuberous Sclerosis Complex: A Review of the Current Literature.
[image: http:--linkinghub.elsevier.com-ihub-imag] Related Articles *Long-Term Everolimus Treatment in Individuals With Tuberous Sclerosis Complex: A Review of the Current Literature.* Pediatr Neurol. 2015 Jul;53(1):23-30 Authors: Tran LH, Zupanc ML Abstract BACKGROUND: Tuberous sclerosis complex is a genetic disease usually caused by mutations to either TSC1 or TSC2, where its gene products are involved in the inhibition of the mammalian target of rapamycin pathway. Under normal cellular conditions, mammalian target of rapamycin (mTOR) regulates cell growth and proliferation in r... περισσότερα »
Rare brainstem oligodendroglioma in an adult patient: Presentation, molecular characteristics and treatment response.
[image: http:--linkinghub.elsevier.com-ihub-imag] Related Articles *Rare brainstem oligodendroglioma in an adult patient: Presentation, molecular characteristics and treatment response.* J Neurol Sci. 2015 Aug 15;355(1-2):209-10 Authors: Hodges SD, Malafronte P, Gilhooly J, Skinner W, Carter C, Theeler BJ PMID: 26048048 [PubMed - indexed for MEDLINE] from Head and Neck on PubMed via xlomafota13 on Inoreader http://ift.tt/1Sj4zNP via IFTTT
A rare case of a heavily calcified gastrointestinal stromal tumors with an intraluminal growth pattern.
[image: http:--http://ift.tt/1iA58YG] Related Articles *A rare case of a heavily calcified gastrointestinal stromal tumors with an intraluminal growth pattern.* Turk J Gastroenterol. 2015 May;26(3):277-8 Authors: Lai WJ, Xu YK PMID: 26006207 [PubMed - indexed for MEDLINE] from Head and Neck on PubMed via xlomafota13 on Inoreader http://ift.tt/1My4uZX via IFTTT
Hemolymphangioma of the spleen: A report of a rare case.
[image: http:--http://ift.tt/1YyhL4R] [image: http:--http://ift.tt/1Fkw4zC] Related Articles *Hemolymphangioma of the spleen: A report of a rare case.* World J Gastroenterol. 2015 May 7;21(17):5442-4 Authors: Mei Y, Peng CJ, Chen L, Li XX, Li WN, Shu DJ, Xie WT Abstract Hemolymphangioma is a malformation of both lymphatic vessels and blood vessels. Splenic hemolymphangioma is extremely rare. Herein, we present a case of 62-year-old woman with ambiguous upper quadrant abdominal pain for two months who was found to have an occupying lesion in the spleen on computed tomography. She ... περισσότερα »
Improving recognition of hepatic perivascular epithelioid cell tumor: Case report and literature review.
[image: http:--http://ift.tt/1YyhL4R] [image: http:--http://ift.tt/1Fkw4zC] Related Articles *Improving recognition of hepatic perivascular epithelioid cell tumor: Case report and literature review.* World J Gastroenterol. 2015 May 7;21(17):5432-41 Authors: Maebayashi T, Abe K, Aizawa T, Sakaguchi M, Ishibashi N, Abe O, Takayama T, Nakayama H, Matsuoka S, Nirei K, Nakamura H, Ogawa M, Sugitani M Abstract A 58-year-old man presented with the chief complaint of abdominal bloating and was incidentally found to have a liver tumor. As diagnostic imaging studies could not rule out mali... περισσότερα »
Primary retroperitoneal mucinous cystadenoma: A case report.
[image: http:--http://ift.tt/1YyhL4R] [image: http:--http://ift.tt/1Fkw4zC] Related Articles *Primary retroperitoneal mucinous cystadenoma: A case report.* World J Gastroenterol. 2015 May 7;21(17):5427-31 Authors: Knezevic S, Ignjatovic I, Lukic S, Matic S, Dugalic V, Knezevic D, Micev M, Dragasevic S Abstract Primary retroperitoneal mucinous cystic tumors are extremely rare. These tumors can be classified as a primary retroperitoneal mucinous cystadenoma with or without borderline malignancy or primary retroperitoneal mucinous cystadenocarcinoma. The most common of these is prim... περισσότερα »
BAP1 mutation is a frequent somatic event in peritoneal malignant mesothelioma.
[image: http:--http://ift.tt/1NMOrDk] [image: http:--http://ift.tt/1Fkw4zC] Related Articles *BAP1 mutation is a frequent somatic event in peritoneal malignant mesothelioma.* J Transl Med. 2015;13:122 Authors: Alakus H, Yost SE, Woo B, French R, Lin GY, Jepsen K, Frazer KA, Lowy AM, Harismendy O Abstract BACKGROUND: Malignant mesothelioma (MM) arises from mesothelial cells that line the pleural, peritoneal and pericardial surfaces. The majority of MMs are pleural and have been associated with asbestos exposure. Previously, pleural MMs have been genetically characterized by the l... περισσότερα »
Primary intracranial low-grade fibromyxoid sarcoma with FUS gene rearrangement.
[image: http:--media.wiley.com-assets-7315-19-Wi] Related Articles *Primary intracranial low-grade fibromyxoid sarcoma with FUS gene rearrangement.* Neuropathology. 2015 Aug;35(4):348-53 Authors: Chen N, Gong J, Nie L, Chen X, Xu M, Chen M, Zhou Q Abstract Low-grade fibromyxoid sarcoma (LGFMS) is a rare sarcoma typically presenting as a deep soft tissue mass in the lower extremities or trunk. Only four cases of primary intracranial LGFMS have been reported in the literature, but none with molecular/cytogenetic data. We report here a new bona fide case confirmed by the characteris... περισσότερα »
The last innovation in achalasia treatment; per-oral endoscopic myotomy.
[image: http:--http://ift.tt/1iA58YG] Related Articles *The last innovation in achalasia treatment; per-oral endoscopic myotomy.* Turk J Gastroenterol. 2015 May;26(3):218-23 Authors: Aslan F, Akpınar Z, Alper E, Atay A, Yurtlu DA, Çekiç C, Bor S, Ünsal B Abstract BACKGROUND/AIMS: Per-oral endoscopic myotomy (POEM) is a minimally invasive endoscopic treatment option for patients with achalasia and has been performed since 2010. It is less invasive than Heller myotomy and its use is spreading rapidly worldwide. We present our results of POEM that, to the best of our knowledge, are ... περισσότερα »
[Proarrhythmic effects of domperidone in infants: a systematic review].
Related Articles *[Proarrhythmic effects of domperidone in infants: a systematic review].* Farm Hosp. 2014 Sep-Oct;38(5):438-44 Authors: Caraballo L, Molina G, Weitz D, Piskulic L, Avila A, Marzi M Abstract AIMS: To assess the association of the use of domperidone in infants with QTc interval prolongation and proarrhythmic events. METHODS: A systematic search of the scientific literature was conducted without any date or language restriction. The electronic database MEDLINE and the sources LILACS, ScIELO and Cochrane library were consulted. RESULTS: From the twelve identified studi... περισσότερα »
DESCENDING NECROTIZING MEDIASTINITIS SECONDARY TO RETROPHARYNGEAL ABSCESS.
*DESCENDING NECROTIZING MEDIASTINITIS SECONDARY TO RETROPHARYNGEAL ABSCESS.* Acta Clin Croat. 2015 Dec;54(4):541-6 Authors: Kovacić M, Kovacić I, Dželalija B Abstract Descending necrotizing mediastinitis secondary to a nontraumatic retropharyngeal abscess is very rare. This form of mediastinitis in the era of potent antibiotics often ends up with lethal outcome. It usually occurs in immunocompromised patients and requires intensive multidisciplinary treatment approach. We report a case of nontraumatic retropharyngeal abscess complicated by descending necrotizing mediastinitis in a... περισσότερα »
Thyroid Dysfunction in Children Exposed to Iodinated Contrast Media.
*Thyroid Dysfunction in Children Exposed to Iodinated Contrast Media.* J Clin Endocrinol Metab. 2016 Mar 28;:jc20161330 Authors: Barr ML, Chiu HK, Li N, Yeh MW, Rhee CM, Casillas J, Iskander PJ, Leung AM Abstract CONTEXT: Iodinated contrast media (ICM) is routinely used in imaging studies and contains several hundred-fold times the recommended daily allowance of iodine. OBJECTIVE: To determine whether children exposed to ICM have a higher risk of iodine-induced thyroid dysfunction. DESIGN: This was a single-institution case-control study, examining patients with incident thyroid d...περισσότερα »
How to diagnose mould allergy? Comparison of skin prick tests with specific IgE results
Abstract Background Diagnosis of mould allergy is complicated due to the heterogeneity of the test material and the decrease in the number of commercial mould skin test solutions that are currently available. Objectives The aim of the present study was to compare skin prick tests (SPT) from different manufacturers to one another and concurrently with… Continue reading How to diagnose mould allergy? Comparison of skin prick tests with specific IgE results
Metabolite profiling of the multiple tyrosine kinase inhibitor lenvatinib: a cross-species comparison
Summary Lenvatinib is an oral, multiple receptor tyrosine kinase inhibitor. Preclinical drug metabolism studies showed unique metabolic pathways for lenvatinib in monkeys and rats. A human mass balance study demonstrated that lenvatinib related material is mainly excreted via feces with a small fraction as unchanged parent drug, but little is reported about its metabolic fate.… Continue reading Metabolite profiling of the multiple tyrosine kinase inhibitor lenvatinib: a cross-species comparison
Eosinophilic Skin Diseases: A Comprehensive Review
Abstract Eosinophilic skin diseases, commonly termed as eosinophilic dermatoses, refer to a broad spectrum of skin diseases characterized by eosinophil infiltration and/or degranulation in skin lesions, with or without blood eosinophilia. The majority of eosinophilic dermatoses lie in the allergy-related group, including allergic drug eruption, urticaria, allergic contact dermatitis, atopic dermatitis, and eczema. Parasitic infestations,… Continue reading Eosinophilic Skin Diseases: A Comprehensive Review
Eosinophilic Drug Allergy
Abstract While peripheral or tissue eosinophilia may certainly characterize drug eruptions, this feature is hardly pathognomonic for a medication-induced etiology. While delayed drug hypersensitivity reactions with prominent eosinophilic recruitment have been typically classified as type IVb reactions, their pathophysiology is now known to be more complex. Eosinophilic drug reactions have a diversity of presentations and… Continue reading Eosinophilic Drug Allergy
Computational modelling of movement-related beta-oscillatory dynamics in human motor cortex
Publication date: June 2016 Source:NeuroImage, Volume 133 Author(s): Mrudul B. Bhatt, Stephanie Bowen, Holly E. Rossiter, Joshua Dupont-Hadwen, Rosalyn J. Moran, Karl J. Friston, Nick S. Ward Oscillatory activity in the beta range, in human primary motor cortex (M1), shows interesting dynamics that are tied to behaviour and change systematically in disease. To investigate the… Continue reading Computational modelling of movement-related beta-oscillatory dynamics in human motor cortex
Study finds brain’s response to social exclusion is different in young marijuana users
A study from Massachusetts General Hospital (MGH) researchers finds that the brains of young adult marijuana users react differently to social exclusion than do those of non-users. from #Medicine-Sfakianakis via simeraentaxei on Inoreader http://ift.tt/25tU5F1 via IFTTT
Vascular brain injury is evident in people in their 40s
A large, multi-center study led by the UC Davis School of Medicine for the first time has shown that people as young as their 40s have stiffening of the arteries that is associated with subtle… from #Medicine-Sfakianakis via simeraentaxei on Inoreader http://ift.tt/1Sj2VMa via IFTTT
Thyroid Dysfunction in Children Exposed to Iodinated Contrast Media.
*Thyroid Dysfunction in Children Exposed to Iodinated Contrast Media.* J Clin Endocrinol Metab. 2016 Mar 28;:jc20161330 Authors: Barr ML, Chiu HK, Li N, Yeh MW, Rhee CM, Casillas J, Iskander PJ, Leung AM Abstract CONTEXT: Iodinated contrast media (ICM) is routinely used in imaging studies and contains several hundred-fold times the recommended daily allowance of iodine. OBJECTIVE: To determine whether children exposed to ICM have a higher risk of iodine-induced thyroid dysfunction. DESIGN: This was a single-institution case-control study, examining patients with incident thyroid d...περισσότερα »
Acyclovir-loaded sorbitan esters-based organogel: development and rheological characterization.
*Acyclovir-loaded sorbitan esters-based organogel: development and rheological characterization.* Artif Cells Nanomed Biotechnol. 2016 Mar 26;:1-9 Authors: Rajpoot K Abstract Herein, a nanoemulsion-based organogel (NEOG) system loaded with acyclovir has been developed for the effective treatment of herpes simplex virus infection via topical delivery. Pseudo-ternary phase diagram exhibited increase in non-birefrigent, optically isotropic region of organogel with Smix (Kw) ratio. The NEOG C showed good storage (G') and loss moduli (G″), and more compact network structures. Gel-sol ... περισσότερα »
Phages in modified alginate beads.
*Phages in modified alginate beads.* Artif Cells Nanomed Biotechnol. 2016 Mar 26;:1-7 Authors: Moghtader F, Eğri S, Piskin E Abstract In order to increase stabilities and controlled/sustained released of T4 phages were encapsulated within alginate beads which were then coated with chitosan, polyethylene imine (PEI). Quite high loading capacities (over 90%) were achieved in these pH-sensitive microbeads. Coating with those polycations increased significantly stability both in "simulated gastric fluid" and bile salts especially in the case of PEI coating. The tests conducted in "si... περισσότερα »
Exemestane encapsulated vitamin E-TPGS-polymeric nanoparticles: preparation, optimization, characterization, and in vitro cytotoxicity assessment.
*Exemestane encapsulated vitamin E-TPGS-polymeric nanoparticles: preparation, optimization, characterization, and in vitro cytotoxicity assessment.* Artif Cells Nanomed Biotechnol. 2016 Mar 26;:1-13 Authors: Mishra B, Padaliya R, Patel RR Abstract The objective of the present study was to formulate and optimize exemestane (EXM) encapsulated vitamin E-TPGS-poly-ɛ-caprolactone based polymeric nanoparticles (TPGS-PCLNPs) for enhancing its anticancer efficacy. The 2(3) factorial design was employed to investigate the combined influence of formulation and process variables on properti...περισσότερα »
Bio-fabrication and statistical optimization of polysorbate 80 coated chitosan nanoparticles of tapentadol hydrochloride for central antinociceptive effect: in vitro-in vivo studies.
*Bio-fabrication and statistical optimization of polysorbate 80 coated chitosan nanoparticles of tapentadol hydrochloride for central antinociceptive effect: in vitro-in vivo studies.* Artif Cells Nanomed Biotechnol. 2016 Mar 26;:1-10 Authors: Patil GB, Surana SJ Abstract Tapentadol hydrochloride (TPD) is a novel analgesic with two mechanisms of actions: agonist activity at the μ-opioid receptor and norepinephrine reuptake inhibition. The conventional delivery of TPD is problematic, owing to its extensive first pass metabolism, low lipophilicity and short half-life that leads to ... περισσότερα »
3D-2D Deformable Image Registration Using Feature-Based Nonuniform Meshes.
*3D-2D Deformable Image Registration Using Feature-Based Nonuniform Meshes.* Biomed Res Int. 2016;2016:4382854 Authors: Zhong Z, Guo X, Cai Y, Yang Y, Wang J, Jia X, Mao W Abstract By using prior information of planning CT images and feature-based nonuniform meshes, this paper demonstrates that volumetric images can be efficiently registered with a very small portion of 2D projection images of a Cone-Beam Computed Tomography (CBCT) scan. After a density field is computed based on the extracted feature edges from planning CT images, nonuniform tetrahedral meshes will be automatical... περισσότερα »
French validation of the Barcelona Music Reward Questionnaire.
*French validation of the Barcelona Music Reward Questionnaire.* PeerJ. 2016;4:e1760 Authors: Saliba J, Lorenzo-Seva U, Marco-Pallares J, Tillmann B, Zeitouni A, Lehmann A Abstract Background. The Barcelona Music Reward Questionnaire (BMRQ) questionnaire investigates the main facets of music experience that could explain the variance observed in how people experience reward associated with music. Currently, only English and Spanish versions of this questionnaire are available. The objective of this study is to validate a French version of the BMRQ. Methods. The original BMRQ was ...περισσότερα »
A Phase II Clinical Trial of Concurrent Helical Tomotherapy plus Cetuximab Followed by Adjuvant Chemotherapy with Cisplatin and Docetaxel for Locally Advanced Nasopharyngeal Carcinoma.
*A Phase II Clinical Trial of Concurrent Helical Tomotherapy plus Cetuximab Followed by Adjuvant Chemotherapy with Cisplatin and Docetaxel for Locally Advanced Nasopharyngeal Carcinoma.* Int J Biol Sci. 2016;12(4):446-453 Authors: Zhang X, Du L, Zhao F, Wang Q, Yang S, Ma L Abstract Purpose: The present clinical trial was designed to evaluate the efficacy and safety of concurrent helical tomotherapy (HT) with cetuximab followed by adjuvant chemotherapy with docetaxel and cisplatin (TP) in the treatment of patients with locoregionally advanced nasopharyngeal carcinoma. Materials a...περισσότερα »
The American College of Surgeons National Surgical Quality Improvement Program Surgical Risk Calculator Does Not Accurately Predict Risk of 30-Day Complications Among Patients Undergoing Microvascular Head and Neck Reconstruction.
*The American College of Surgeons National Surgical Quality Improvement Program Surgical Risk Calculator Does Not Accurately Predict Risk of 30-Day Complications Among Patients Undergoing Microvascular Head and Neck Reconstruction.* J Oral Maxillofac Surg. 2016 Mar 3; Authors: Arce K, Moore EJ, Lohse CM, Reiland MD, Yetzer JG, Ettinger KS Abstract PURPOSE: The American College of Surgeons (ACS) National Surgical Quality Improvement Program (NSQIP) Surgical Risk Calculator (SRC) is a novel universal risk calculator designed to aid in risk stratification of patients undergoing vari... περισσότερα »
Case Reports of Two Unusual Donor Site Complications of the Pectoralis Major Myocutaneous Flap and Literature Review.
*Case Reports of Two Unusual Donor Site Complications of the Pectoralis Major Myocutaneous Flap and Literature Review.* J Oral Maxillofac Surg. 2016 Mar 3; Authors: Kim B, Kaleem A, Zaid W Abstract The pectoralis major myocutaneous flap (PMMF) for head and neck reconstruction was first introduced by Ariyan in 1979. For many subsequent years, it was considered a workhorse flap and is still widely used for a wide range of head and neck reconstructions, especially in developing countries, owing to its ease of harvest, reliability, versatility, proximity to the head and neck region, ...περισσότερα »
Intraoperative Image Guidance Improves Outcomes in Complex Orbital Reconstruction by Novice Surgeons.
*Intraoperative Image Guidance Improves Outcomes in Complex Orbital Reconstruction by Novice Surgeons.* J Oral Maxillofac Surg. 2016 Mar 3; Authors: Davis KS, Vosler PS, Yu J, Wang EW Abstract PURPOSE: This study aims to describe the utility of surgical navigation in improving operative outcomes in complex orbital reconstruction by novice compared with experienced surgical trainees. MATERIALS AND METHODS: A randomized, controlled cadaveric study was conducted at the University of Pittsburgh School of Medicine with otolaryngology and ophthalmology residents and fellows. Participant... περισσότερα »
Radiation therapy (with or without neck surgery) for phenotypic human papillomavirus-associated oropharyngeal cancer.
*Radiation therapy (with or without neck surgery) for phenotypic human papillomavirus-associated oropharyngeal cancer.* Cancer. 2016 Mar 28; Authors: Garden AS, Fuller CD, Rosenthal DI, William WN, Gunn GB, Beadle BM, Johnson FM, Morrison WH, Phan J, Frank SJ, Kies MS, Sturgis EM Abstract BACKGROUND: Favorable outcomes for human papillomavirus-associated oropharyngeal cancer have led to interest in identifying a subgroup of patients with the lowest risk of disease recurrence after therapy. De-intensification of therapy for this group may result in survival outcomes that are simil... περισσότερα »
Treatment trends and survival effects of chemotherapy for hypopharyngeal cancer: Analysis of the National Cancer Data Base.
*Treatment trends and survival effects of chemotherapy for hypopharyngeal cancer: Analysis of the National Cancer Data Base.* Cancer. 2016 Mar 28; Authors: Kuo P, Sosa JA, Burtness BA, Husain ZA, Mehra S, Roman SA, Yarbrough WG, Judson BL Abstract BACKGROUND: The current study was performed to characterize trends and survival outcomes for chemotherapy in the definitive and adjuvant treatment of hypopharyngeal cancer in the United States. METHODS: A total of 16,248 adult patients diagnosed with primary hypopharyngeal cancer without distant metastases between 1998 and 2011 were ide... περισσότερα »
Retrograde intra-arterial chemotherapy and daily concurrent proton beam therapy for recurrent oral cavity squamous cell carcinoma: Analysis of therapeutic results in 46 cases.
*Retrograde intra-arterial chemotherapy and daily concurrent proton beam therapy for recurrent oral cavity squamous cell carcinoma: Analysis of therapeutic results in 46 cases.* Head Neck. 2016 Mar 28; Authors: Hayashi Y, Nakamura T, Mitsudo K, Yamaguchi H, Ono T, Azami Y, Takayama K, Suzuki M, Hatayama Y, Tsukiyama I, Hareyama M, Kikuchi Y, Fuwa N, Tohnai I Abstract BACKGROUND: The purpose of this study was to evaluate the efficacy and toxicities of proton beam therapy combined with intra-arterial infusion chemotherapy via superficial temporal and occipital arteries for recurren...περισσότερα »
The Role of Military Plastic Surgeons in the Management of Modern Combat Trauma: An Analysis of 645 Cases.
*The Role of Military Plastic Surgeons in the Management of Modern Combat Trauma: An Analysis of 645 Cases.* Plast Reconstr Surg. 2016 Apr;137(4):717e-724e Authors: Maitland L, Lawton G, Baden J, Cubison T, Rickard R, Kay A, Hettiaratchy S Abstract BACKGROUND: Plastic surgery has historically been linked to war. Between 2008 and the end of combat operations in Afghanistan in 2014, British military plastic surgeons formed part of the multinational military surgical team at the Role 3 Medical Treatment Facility, Camp Bastion, Helmand Province. The present study aimed to analyze the...περισσότερα »
Surgical Management of Obstructive Sleep Apnea.
*Surgical Management of Obstructive Sleep Apnea.* Plast Reconstr Surg. 2016 Apr;137(4):1263-1272 Authors: Tanna N, Smith BD, Zapanta PE, Karanetz I, Andrews BT, Urata MM, Bradley JP Abstract Surgical management of snoring and obstructive sleep apnea is indicated when a surgically correctable abnormality is believed to be the source of the problem. Many patients opt for surgical treatment after noninvasive forms of treatment have been proven ineffective or difficult to tolerate. With increasing frequency, functional rhinoplasty, septoplasty, turbinoplasty, palatal surgery, and ort...περισσότερα »
A Comparative Assessment of Three Formulations of Botulinum Toxin Type A for Facial Rhytides: A Systematic Review with Meta-Analyses.
*A Comparative Assessment of Three Formulations of Botulinum Toxin Type A for Facial Rhytides: A Systematic Review with Meta-Analyses.* Plast Reconstr Surg. 2016 Apr;137(4):1125-1140 Authors: Bonaparte JP, Ellis D, Quinn JG, Rabski J, Hutton B Abstract BACKGROUND: Three formulations of botulinum toxin are available for facial rhytides. It is unclear which formulation offers the greatest balance of benefits and harms. The objective of this study was to conduct a systematic review with meta-analyses to compare formulations of botulinum toxin for reduction of facial rhytides at the g... περισσότερα »
Schwannoma (Neurilemmoma) on the Base of the Tongue: A Rare Clinical Case.
*Schwannoma (Neurilemmoma) on the Base of the Tongue: A Rare Clinical Case.* Am J Case Rep. 2016;17:203-206 Authors: Sharma S, Rai G Abstract BACKGROUND Schwannomas are slow-growing benign tumors. They can arise from any peripheral nerve, including the cranial nerves (except the olfactory and optic nerves), spinal nerves, and autonomic nerves. Schwannomas of the head and neck account for 25-40% of all cases. However, intra-oral schwannomas account for only 1% of all head and neck tumors. Complete surgical excision is the treatment of choice. Malignant transformation and recurrenc... περισσότερα »
Sequencing the GRHL3 Coding Region Reveals Rare Truncating Mutations and a Common Susceptibility Variant for Nonsyndromic Cleft Palate.
*Sequencing the GRHL3 Coding Region Reveals Rare Truncating Mutations and a Common Susceptibility Variant for Nonsyndromic Cleft Palate.* Am J Hum Genet. 2016 Mar 22; Authors: Mangold E, Böhmer AC, Ishorst N, Hoebel AK, Gültepe P, Schuenke H, Klamt J, Hofmann A, Gölz L, Raff R, Tessmann P, Nowak S, Reutter H, Hemprich A, Kreusch T, Kramer FJ, Braumann B, Reich R, Schmidt G, Jäger A, Reiter R, Brosch S, Stavusis J, Ishida M, Seselgyte R, Moore GE, Nöthen MM, Borck G, Aldhorae KA, Lace B, Stanier P, Knapp M, Ludwig KU Abstract Nonsyndromic cleft lip with/without cleft palate (nsCL/P... περισσότερα »
Isolation of biologically active and morphologically intact exosomes from plasma of patients with cancer.
*Isolation of biologically active and morphologically intact exosomes from plasma of patients with cancer.* J Extracell Vesicles. 2016;5:29289 Authors: Hong CS, Funk S, Muller L, Boyiadzis M, Whiteside TL Abstract OBJECTIVE: Isolation from human plasma of exosomes that retain functional and morphological integrity for probing their protein, lipid and nucleic acid content is a priority for the future use of exosomes as biomarkers. A method that meets these criteria and can be scaled up for patient monitoring is thus desirable. METHODS: Plasma specimens (1 mL) of patients with acute...περισσότερα »
Updated overview of current biomarkers in head and neck carcinoma.
*Updated overview of current biomarkers in head and neck carcinoma.* World J Methodol. 2016 Mar 26;6(1):77-86 Authors: Dahiya K, Dhankhar R Abstract Squamous cell cancer is the most common type of malignancy arising from the epithelial cells of the head and neck region. Head and neck squamous cell carcinoma (HNSCC) is one of the predominant causes of cancer related casualties worldwide. Overall prognosis in this disease has improved to some extent with the advancements in therapeutic modalities but detection of primary tumor at its initial stage and prevention of relapse are the ... περισσότερα »
EGJ outflow obstruction must be excluded in patients with high IRP and weak peristalsis.
[image: http:--http://ift.tt/1iA58YG] Related Articles *EGJ outflow obstruction must be excluded in patients with high IRP and weak peristalsis.* Turk J Gastroenterol. 2015 May;26(3):288 Authors: Sakin YS, Çelebi G, Kekilli M, Uygun A, Bağcı S PMID: 26006213 [PubMed - indexed for MEDLINE] from Swallowing and Swallowing Disorders (Dysphagia) via xlomafota13 on Inoreader http://ift.tt/1VRePTd via IFTTT
The last innovation in achalasia treatment; per-oral endoscopic myotomy.
[image: http:--http://ift.tt/1iA58YG] Related Articles *The last innovation in achalasia treatment; per-oral endoscopic myotomy.* Turk J Gastroenterol. 2015 May;26(3):218-23 Authors: Aslan F, Akpınar Z, Alper E, Atay A, Yurtlu DA, Çekiç C, Bor S, Ünsal B Abstract BACKGROUND/AIMS: Per-oral endoscopic myotomy (POEM) is a minimally invasive endoscopic treatment option for patients with achalasia and has been performed since 2010. It is less invasive than Heller myotomy and its use is spreading rapidly worldwide. We present our results of POEM that, to the best of our knowledge, are ... περισσότερα »
[Gastrointestinal foreign body in children].
[image: http:--http://ift.tt/1R8xNmj] Related Articles *[Gastrointestinal foreign body in children].* Rev Chil Pediatr. 2014 Dec;85(6):682-9 Authors: Muñoz F MP, Maluje J R, Saitua D F Abstract UNLABELLED: Gastrointestinal foreign bodies (FB) are frequent complaints in the emergency departments, with esophageal foreign bodies as the most frequent cases. Symptoms are varied and depend on the location of the FB, with several techniques available for removal. OBJECTIVE: To describe the FB removed by endoscopy in children as well as the consulting population characteristics. PATIENTS ... περισσότερα »
[Proarrhythmic effects of domperidone in infants: a systematic review].
Related Articles *[Proarrhythmic effects of domperidone in infants: a systematic review].* Farm Hosp. 2014 Sep-Oct;38(5):438-44 Authors: Caraballo L, Molina G, Weitz D, Piskulic L, Avila A, Marzi M Abstract AIMS: To assess the association of the use of domperidone in infants with QTc interval prolongation and proarrhythmic events. METHODS: A systematic search of the scientific literature was conducted without any date or language restriction. The electronic database MEDLINE and the sources LILACS, ScIELO and Cochrane library were consulted. RESULTS: From the twelve identified studi... περισσότερα »
Can Dysphagia Following Anterior Cervical Fusions With rhBMP-2 Be Reduced With Local Depomedrol Application?: A Prospective, Randomized, Placebo-Controlled, Double-Blind Trial.
*Can Dysphagia Following Anterior Cervical Fusions With rhBMP-2 Be Reduced With Local Depomedrol Application?: A Prospective, Randomized, Placebo-Controlled, Double-Blind Trial.* Spine (Phila Pa 1976). 2016 Apr;41(7):555-562 Authors: Edwards CC, Dean C, Edwards CC, Phillips D, Blight A Abstract STUDY DESIGN: A prospective, randomized, placebo-controlled, double-blind trial. OBJECTIVE: The aim of this study was to investigate whether the local administration of depomedrol decreases the severity of dysphagia after anterior cervical discectomy and fusion (ACDF) surgery using bone mo... περισσότερα »
Severe dysphagia, myalgia, and rash in a 55-year-old man.
*Severe dysphagia, myalgia, and rash in a 55-year-old man.* J Dtsch Dermatol Ges. 2016 Mar 28; Authors: Prossliner V, Philipp M, Moosbrugger V, Poewe W, Zangerle R, Wanschitz J, Schmuth M PMID: 27018866 [PubMed - as supplied by publisher] from Swallowing and Swallowing Disorders (Dysphagia) via xlomafota13 on Inoreader http://ift.tt/1VReSOK
[Anesthetic Management for a Patient with Stiff-person Syndrome].
*[Anesthetic Management for a Patient with Stiff-person Syndrome].* Masui. 2016 Feb;65(2):164-7 Authors: Nakamura K, Murao K, Kimoto-Shirakawa M, Takahira K, Toorabally F, Shingu K Abstract The stiff-person syndrome (SPS) is a rare autoimmune neurologic disorder that affects the gamma-aminobutyric acid (GABA) mediated inhibitory network in the central nervous system with anti-glutamic acid decarboxylase (GAD) antibodies. SPS is characterized by muscle rigidity and painful episodic spasms in axial and lower limb muscles. This case report describes successful peri-operative managem... περισσότερα »
THE TRIBES AND TRIBULATIONS OF LARYNGOPHARYNGEAL REFLUX: A REVIEW OF RECENT STUDIES WITH IMPLICATIONS FOR INTERDISCIPLINARY COLLABORATIONS BETWEEN OTOLARYNGOLOGISTS AND GASTROENTEROLOGISTS.
Related Articles *THE TRIBES AND TRIBULATIONS OF LARYNGOPHARYNGEAL REFLUX: A REVIEW OF RECENT STUDIES WITH IMPLICATIONS FOR INTERDISCIPLINARY COLLABORATIONS BETWEEN OTOLARYNGOLOGISTS AND GASTROENTEROLOGISTS.* Rev Med Chir Soc Med Nat Iasi. 2015 Oct-Dec;119(4):967-73 Authors: Bărboi OB, Prelipcean CC, Cobzeanu MD, Palade D, Albu-Soda A, Floria M, Chirilă I, Drug VL, Bălan G Abstract Laryngopharyngeal reflux has been recognized since 2006 (Montreal Consensus) as an extradigestive manifestation of gastroesophageal reflux disease. However, despite numerous research studies, the relati... περισσότερα »
[Risk-benefit of anti-reflux therapy in the premature infant].
[image: http:--linkinghub.elsevier.com-ihub-imag] *[Risk-benefit of anti-reflux therapy in the premature infant].* Arch Pediatr. 2015 May;22(5 Suppl 1):206-7 Authors: Mouterde O PMID: 26112594 [PubMed - indexed for MEDLINE] from Swallowing and Swallowing Disorders (Dysphagia) via xlomafota13 on Inoreader http://ift.tt/1VReSOB
EGJ outflow obstruction must be excluded in patients with high IRP and weak peristalsis.
[image: http:--http://ift.tt/1iA58YG] Related Articles *EGJ outflow obstruction must be excluded in patients with high IRP and weak peristalsis.* Turk J Gastroenterol. 2015 May;26(3):288 Authors: Sakin YS, Çelebi G, Kekilli M, Uygun A, Bağcı S PMID: 26006213 [PubMed - indexed for MEDLINE] from Swallowing and Swallowing Disorders (Dysphagia) via xlomafota13 on Inoreader http://ift.tt/1VRePTd
The last innovation in achalasia treatment; per-oral endoscopic myotomy.
[image: http:--http://ift.tt/1iA58YG] Related Articles *The last innovation in achalasia treatment; per-oral endoscopic myotomy.* Turk J Gastroenterol. 2015 May;26(3):218-23 Authors: Aslan F, Akpınar Z, Alper E, Atay A, Yurtlu DA, Çekiç C, Bor S, Ünsal B Abstract BACKGROUND/AIMS: Per-oral endoscopic myotomy (POEM) is a minimally invasive endoscopic treatment option for patients with achalasia and has been performed since 2010. It is less invasive than Heller myotomy and its use is spreading rapidly worldwide. We present our results of POEM that, to the best of our knowledge, are t... περισσότερα »
[Proarrhythmic effects of domperidone in infants: a systematic review].
Related Articles *[Proarrhythmic effects of domperidone in infants: a systematic review].* Farm Hosp. 2014 Sep-Oct;38(5):438-44 Authors: Caraballo L, Molina G, Weitz D, Piskulic L, Avila A, Marzi M Abstract AIMS: To assess the association of the use of domperidone in infants with QTc interval prolongation and proarrhythmic events. METHODS: A systematic search of the scientific literature was conducted without any date or language restriction. The electronic database MEDLINE and the sources LILACS, ScIELO and Cochrane library were consulted. RESULTS: From the twelve identified studie... περισσότερα »
THE TRIBES AND TRIBULATIONS OF LARYNGOPHARYNGEAL REFLUX: A REVIEW OF RECENT STUDIES WITH IMPLICATIONS FOR INTERDISCIPLINARY COLLABORATIONS BETWEEN OTOLARYNGOLOGISTS AND GASTROENTEROLOGISTS.
Related Articles *THE TRIBES AND TRIBULATIONS OF LARYNGOPHARYNGEAL REFLUX: A REVIEW OF RECENT STUDIES WITH IMPLICATIONS FOR INTERDISCIPLINARY COLLABORATIONS BETWEEN OTOLARYNGOLOGISTS AND GASTROENTEROLOGISTS.* Rev Med Chir Soc Med Nat Iasi. 2015 Oct-Dec;119(4):967-73 Authors: Bărboi OB, Prelipcean CC, Cobzeanu MD, Palade D, Albu-Soda A, Floria M, Chirilă I, Drug VL, Bălan G Abstract Laryngopharyngeal reflux has been recognized since 2006 (Montreal Consensus) as an extradigestive manifestation of gastroesophageal reflux disease. However, despite numerous research studies, the relati... περισσότερα »
A Meta-Analysis of Randomized Controlled Trials to Compare Long-Term Outcomes of Nissen and Toupet Fundoplication for Gastroesophageal Reflux Disease.
[image: http:--http://ift.tt/1II1iHB] [image: http:--http://ift.tt/1Fkw4zC] Related Articles *A Meta-Analysis of Randomized Controlled Trials to Compare Long-Term Outcomes of Nissen and Toupet Fundoplication for Gastroesophageal Reflux Disease.* PLoS One. 2015;10(6):e0127627 Authors: Tian ZC, Wang B, Shan CX, Zhang W, Jiang DZ, Qiu M Abstract AIM: In recent years, several studies with large sample sizes and recent follow-up data have been published comparing outcomes between laparoscopic Nissen fundoplication and laparoscopic Toupet fundoplication. It is now timely to be re-evalu... περισσότερα »
[Risk-benefit of anti-reflux therapy in the premature infant].
[image: http:--linkinghub.elsevier.com-ihub-imag] *[Risk-benefit of anti-reflux therapy in the premature infant].* Arch Pediatr. 2015 May;22(5 Suppl 1):206-7 Authors: Mouterde O PMID: 26112594 [PubMed - indexed for MEDLINE] from Swallowing and Swallowing Disorders (Dysphagia) via xlomafota13 on Inoreader http://ift.tt/1VReSOB
EGJ outflow obstruction must be excluded in patients with high IRP and weak peristalsis.
[image: http:--http://ift.tt/1iA58YG] Related Articles *EGJ outflow obstruction must be excluded in patients with high IRP and weak peristalsis.* Turk J Gastroenterol. 2015 May;26(3):288 Authors: Sakin YS, Çelebi G, Kekilli M, Uygun A, Bağcı S PMID: 26006213 [PubMed - indexed for MEDLINE] from Swallowing and Swallowing Disorders (Dysphagia) via xlomafota13 on Inoreader http://ift.tt/1VRePTd
The last innovation in achalasia treatment; per-oral endoscopic myotomy.
[image: http:--http://ift.tt/1iA58YG] Related Articles *The last innovation in achalasia treatment; per-oral endoscopic myotomy.* Turk J Gastroenterol. 2015 May;26(3):218-23 Authors: Aslan F, Akpınar Z, Alper E, Atay A, Yurtlu DA, Çekiç C, Bor S, Ünsal B Abstract BACKGROUND/AIMS: Per-oral endoscopic myotomy (POEM) is a minimally invasive endoscopic treatment option for patients with achalasia and has been performed since 2010. It is less invasive than Heller myotomy and its use is spreading rapidly worldwide. We present our results of POEM that, to the best of our knowledge, are t... περισσότερα »
[Gastrointestinal foreign body in children].
[image: http:--http://ift.tt/1R8xNmj] Related Articles *[Gastrointestinal foreign body in children].* Rev Chil Pediatr. 2014 Dec;85(6):682-9 Authors: Muñoz F MP, Maluje J R, Saitua D F Abstract UNLABELLED: Gastrointestinal foreign bodies (FB) are frequent complaints in the emergency departments, with esophageal foreign bodies as the most frequent cases. Symptoms are varied and depend on the location of the FB, with several techniques available for removal. OBJECTIVE: To describe the FB removed by endoscopy in children as well as the consulting population characteristics. PATIENTS A... περισσότερα »
[Proarrhythmic effects of domperidone in infants: a systematic review].
Related Articles *[Proarrhythmic effects of domperidone in infants: a systematic review].* Farm Hosp. 2014 Sep-Oct;38(5):438-44 Authors: Caraballo L, Molina G, Weitz D, Piskulic L, Avila A, Marzi M Abstract AIMS: To assess the association of the use of domperidone in infants with QTc interval prolongation and proarrhythmic events. METHODS: A systematic search of the scientific literature was conducted without any date or language restriction. The electronic database MEDLINE and the sources LILACS, ScIELO and Cochrane library were consulted. RESULTS: From the twelve identified studie... περισσότερα »
Arabinoxylan rice bran (MGN-3/Biobran) enhances natural killer cell-mediated cytotoxicity against neuroblastoma in vitro and in vivo.
[image: http:--linkinghub.elsevier.com-ihub-imag] Related Articles *Arabinoxylan rice bran (MGN-3/Biobran) enhances natural killer cell-mediated cytotoxicity against neuroblastoma in vitro and in vivo.* Cytotherapy. 2015 May;17(5):601-12 Authors: Pérez-Martínez A, Valentín J, Fernández L, Hernández-Jiménez E, López-Collazo E, Zerbes P, Schwörer E, Nuñéz F, Martín IG, Sallis H, Díaz MÁ, Handgretinger R, Pfeiffer MM Abstract BACKGROUND AIMS: Natural killer cell (NK) cytotoxic activity plays a major role in natural immunologic defences against malignancies. NK cells are emerging as ... περισσότερα »
The TEL-AML1 fusion protein of acute lymphoblastic leukemia modulates IRF3 activity during early B-cell differentiation.
[image: http:--http://ift.tt/1feGv2I] Related Articles *The TEL-AML1 fusion protein of acute lymphoblastic leukemia modulates IRF3 activity during early B-cell differentiation.* Oncogene. 2015 Dec 3;34(49):6018-28 Authors: de Laurentiis A, Hiscott J, Alcalay M Abstract The t(12;21) translocation is the most common genetic rearrangement in childhood acute lymphoblastic leukemia (ALL) and gives rise to the TEL-AML1 fusion gene. Many studies on TEL-AML1 describe specific properties of the fusion protein, but a thorough understanding of its function is lacking. We exploited a pluripo... περισσότερα »
Opposite Prognostic Significance of Cellular and Serum Circulating MicroRNA-150 in Patients with Chronic Lymphocytic Leukemia.
[image: http:--http://ift.tt/1Fkw4zC] Related Articles *Opposite Prognostic Significance of Cellular and Serum Circulating MicroRNA-150 in Patients with Chronic Lymphocytic Leukemia.* Mol Med. 2015;21:123-33 Authors: Stamatopoulos B, Van Damme M, Crompot E, Dessars B, Housni HE, Mineur P, Meuleman N, Bron D, Lagneaux L Abstract MicroRNAs (or miRs) play a crucial role in chronic lymphocytic leukemia (CLL) physiopathology and prognosis. In addition, circulating microRNAs in body fluids have been proposed as new biomarkers. We investigated the expression of matched cellular and seru... περισσότερα »
Combined inhibition of Chk1 and Wee1 as a new therapeutic strategy for mantle cell lymphoma.
[image: http:--http://ift.tt/1kmBV5b] [image: http:--http://ift.tt/1Fkw4zC] Related Articles *Combined inhibition of Chk1 and Wee1 as a new therapeutic strategy for mantle cell lymphoma.* Oncotarget. 2015 Feb 20;6(5):3394-408 Authors: Chilà R, Basana A, Lupi M, Guffanti F, Gaudio E, Rinaldi A, Cascione L, Restelli V, Tarantelli C, Bertoni F, Damia G, Carrassa L Abstract Mantle cell lymphoma (MCL) is an aggressive, incurable disease, characterized by a deregulated cell cycle. Chk1 and Wee1 are main regulators of cell cycle progression and recent data on solid tumors suggest that ... περισσότερα »
Platinum and high-dose cytarabine-based regimens are efficient in ultra high/high-risk chronic lymphocytic leukemia and Richter's syndrome: results of a French retrospective multicenter study.
[image: http:--media.wiley.com-assets-7315-19-Wi] Related Articles *Platinum and high-dose cytarabine-based regimens are efficient in ultra high/high-risk chronic lymphocytic leukemia and Richter's syndrome: results of a French retrospective multicenter study.* Eur J Haematol. 2015 Aug;95(2):160-7 Authors: Durot E, Michallet AS, Leprêtre S, Le QH, Leblond V, Delmer A Abstract Ultra high-risk chronic lymphocytic leukemia (CLL) and Richter's syndrome (RS) usually display a poor prognosis. Platinum and cytarabine-based regimens have not been evaluated in large cohorts of patients wit... περισσότερα »
Lymphomatoid granulomatosis presenting with cutaneous involvement: a case report and review of the literature.
[image: http:--media.wiley.com-assets-7315-19-Wi] Related Articles *Lymphomatoid granulomatosis presenting with cutaneous involvement: a case report and review of the literature.* J Cutan Pathol. 2015 Mar;42(3):188-93 Authors: Rysgaard CD, Stone MS Abstract Lymphomatoid granulomatosis (LG) is a rare Epstein-Barr virus (EBV)-associated B-cell lymphoproliferative disorder presenting in middle adulthood that nearly always affects the lungs and shows cutaneous involvement in up to 50% of cases. Skin lesions are present at the time of diagnosis in roughly one-third of patients and may... περισσότερα »
New frontiers for brentuximab vedotin for lymphomas.
[image: http:--http://ift.tt/1XLQsFQ] Related Articles *New frontiers for brentuximab vedotin for lymphomas.* Leuk Lymphoma. 2015 Feb;56(2):283-4 Authors: Moskowitz AJ PMID: 25315080 [PubMed - indexed for MEDLINE] from Head and Neck on PubMed via xlomafota13 on Inoreader http://ift.tt/1rycqsW via IFTTT
CD30 in pediatric post-transplant lymphoproliferative disease after solid organ transplant: characterization of a new therapeutic target.
[image: http:--http://ift.tt/1XLQsFQ] Related Articles *CD30 in pediatric post-transplant lymphoproliferative disease after solid organ transplant: characterization of a new therapeutic target.* Leuk Lymphoma. 2015 Mar;56(3):832-3 Authors: Schober T, Framke T, Großhennig A, Klein C, Kreipe H, Maecker-Kolhoff B PMID: 25242095 [PubMed - indexed for MEDLINE] from Head and Neck on PubMed via xlomafota13 on Inoreader http://ift.tt/1v3zvZm via IFTTT
Cholesteroloma: a rare thymic pseudotumor
from Anatomy Pathology via xlomafota13 on Inoreader http://ift.tt/1qdma3b via IFTTT
How to diagnose mould allergy? Comparison of skin prick tests with specific IgE results
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Abstract Background Diagnosis of mould allergy is complicated due to the heterogeneity of the test material and the decrease in the number of commercial mould skin test solutions that are currently available. Objectives The aim of the present study was to compare skin prick tests (SPT) from different manufacturers to one another and concurrently with […]
Metabolite profiling of the multiple tyrosine kinase inhibitor lenvatinib: a cross-species comparison
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Summary Lenvatinib is an oral, multiple receptor tyrosine kinase inhibitor. Preclinical drug metabolism studies showed unique metabolic pathways for lenvatinib in monkeys and rats. A human mass balance study demonstrated that lenvatinib related material is mainly excreted via feces with a small fraction as unchanged parent drug, but little is reported about its metabolic fate. […]
Study finds brain’s response to social exclusion is different in young marijuana users
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
A study from Massachusetts General Hospital (MGH) researchers finds that the brains of young adult marijuana users react differently to social exclusion than do those of non-users. from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/25tU5F1 via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
Vascular brain injury is evident in people in their 40s
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
A large, multi-center study led by the UC Davis School of Medicine for the first time has shown that people as young as their 40s have stiffening of the arteries that is associated with subtle… from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1Sj2VMa via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
Eosinophilic Skin Diseases: A Comprehensive Review
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Abstract Eosinophilic skin diseases, commonly termed as eosinophilic dermatoses, refer to a broad spectrum of skin diseases characterized by eosinophil infiltration and/or degranulation in skin lesions, with or without blood eosinophilia. The majority of eosinophilic dermatoses lie in the allergy-related group, including allergic drug eruption, urticaria, allergic contact dermatitis, atopic dermatitis, and eczema. Parasitic infestations, […]
Eosinophilic Drug Allergy
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Abstract While peripheral or tissue eosinophilia may certainly characterize drug eruptions, this feature is hardly pathognomonic for a medication-induced etiology. While delayed drug hypersensitivity reactions with prominent eosinophilic recruitment have been typically classified as type IVb reactions, their pathophysiology is now known to be more complex. Eosinophilic drug reactions have a diversity of presentations and […]
Lack of IDH1 mutation in astroblastomas suggests putative origin from ependymoglial cells?
[image: http:--media.wiley.com-assets-7315-19-Wi] Related Articles *Lack of IDH1 mutation in astroblastomas suggests putative origin from ependymoglial cells?* Neuropathology. 2015 Aug;35(4):303-11 Authors: Asha U, Mahadevan A, Sathiyabama D, Ravindra T, Sagar BK, Bhat DI, Aravinda HR, Pandey P, Vilanilam GC Abstract Astroblastomas are extremely rare neuroepithelial tumors of uncertain histogenesis, affecting children and young adults, and constitute a new addition to the WHO 2000 classification of CNS tumors. We report the largest series of nine cases diagnosed in a single insti... περισσότερα »
Use of clinical next-generation sequencing to identify melanomas harboring SMARCB1 mutations.
[image: http:--media.wiley.com-assets-7315-19-Wi] Related Articles *Use of clinical next-generation sequencing to identify melanomas harboring SMARCB1 mutations.* J Cutan Pathol. 2015 May;42(5):308-17 Authors: Stockman DL, Curry JL, Torres-Cabala CA, Watson IR, Siroy AE, Bassett RL, Zou L, Patel KP, Luthra R, Davies MA, Wargo JA, Routbort MA, Broaddus RR, Prieto VG, Lazar AJ, Tetzlaff MT Abstract BACKGROUND: SMARCB1 (INI1/BAF47/SNF5) encodes a part of a multiprotein complex that regulates gene expression through chromatin remodeling. SMARCB1 expression is lost or downregulated in...περισσότερα »
Low-Dose CT Screening for Lung Cancer: Computer-aided Detection of Missed Lung Cancers.
*Low-Dose CT Screening for Lung Cancer: Computer-aided Detection of Missed Lung Cancers.* Radiology. 2016 Mar 28;:150063 Authors: Liang M, Tang W, Xu DM, Jirapatnakul AC, Reeves AP, Henschke CI, Yankelevitz D Abstract Purpose To update information regarding the usefulness of computer-aided detection (CAD) systems with a focus on the most critical category, that of missed cancers at earlier imaging, for cancers that manifest as a solid nodule. Materials and Methods By using a HIPAA-compliant institutional review board-approved protocol where informed consent was obtained, 50 lung ...περισσότερα »
Endovascular MR-guided Renal Embolization by Using a Magnetically Assisted Remote-controlled Catheter System.
*Endovascular MR-guided Renal Embolization by Using a Magnetically Assisted Remote-controlled Catheter System.* Radiology. 2016 Mar 28;:152036 Authors: Lillaney PV, Yang JK, Losey AD, Martin AJ, Cooke DL, Thorne BR, Barry DC, Chu A, Stillson C, Do L, Arenson RL, Saeed M, Wilson MW, Hetts SW Abstract Purpose To assess the feasibility of a magnetically assisted remote-controlled (MARC) catheter system under magnetic resonance (MR) imaging guidance for performing a simple endovascular procedure (ie, renal artery embolization) in vivo and to compare with x-ray guidance to determine t... περισσότερα »
Impact of Breast Density Notification Legislation on Radiologists' Practices of Reporting Breast Density: A Multi-State Study.
*Impact of Breast Density Notification Legislation on Radiologists' Practices of Reporting Breast Density: A Multi-State Study.* Radiology. 2016 Mar 28;:152457 Authors: Bahl M, Baker JA, Bhargavan-Chatfield M, Brandt EK, Ghate SV Abstract Purpose To evaluate the impact of breast density notification legislation on breast density reporting by radiologists nationally. Materials and Methods The institutional review board exempted this HIPAA-compliant retrospective study from the requirement for informed consent. State-level data over a 5-year period on breast density categorization a... περισσότερα »
Long-term Graft and Patient Survival after Balloon Dilation of Ureteric Stenosis after Renal Transplant: A 23-year Retrospective Matched Cohort Study.
*Long-term Graft and Patient Survival after Balloon Dilation of Ureteric Stenosis after Renal Transplant: A 23-year Retrospective Matched Cohort Study.* Radiology. 2016 Mar 28;:151629 Authors: Kumar S, Jeon JH, Hakim A, Shrivastava S, Banerjee D, Patel U Abstract Purpose To study long-term graft and patient survival after percutaneous ureteroplasty of ureteric stenosis after renal transplantation and to compare the outcomes to those of patients who did not develop ureteric stenosis. Materials and Methods An ethical waiver was obtained for this 23-year retrospective matched cohort...περισσότερα »
Secondary Neck Lift and the Importance of Midline Platysmaplasty: Review of 101 Cases.
*Secondary Neck Lift and the Importance of Midline Platysmaplasty: Review of 101 Cases.* Plast Reconstr Surg. 2016 Apr;137(4):667e-675e Authors: Narasimhan K, Ramanadham S, O'Reilly E, Rohrich RJ Abstract BACKGROUND: The authors believe that open access to the submental region, platysmaplasty, and wide skin undermining provide the most long-lasting results in neck rejuvenation, and sought to evaluate this hypothesis by reviewing their neck-lift patients. METHODS: The authors performed a retrospective chart review of their experience with neck-lift procedures and patients who under... περισσότερα »
HEPATOPROTECTIVE EFFECT OF DEXMEDETOMIDINE AGAINST RADIOIODINE TOXICITY IN RATS: EVALUATION OF OXIDATIVE STATUS AND HISTOPATHOLOGICAL CHANGES.
*HEPATOPROTECTIVE EFFECT OF DEXMEDETOMIDINE AGAINST RADIOIODINE TOXICITY IN RATS: EVALUATION OF OXIDATIVE STATUS AND HISTOPATHOLOGICAL CHANGES.* Int Surg. 2016 Mar 28; Authors: Kismet K, Sadic M, Bag YM, Atilgan HI, Koca G, Onalan AK, Senes M, Peker SA, Yumusak N, Korkmaz M Abstract OBJECTIVE AND BACKGROUND: Based on the anti-inflammatory, antioxidant and anti-apoptotic properties of DEX, the present study was conducted to investigate the possible radioprotective effects of DEX against hepatic radioiodine (I-131) toxicity. METHODS: Thirty six rats were randomly divided into three ... περισσότερα »
TIMING OF RADIOACTIVE IODINE THERAPY DOES NOT IMPACT OVERALL SURVIVAL IN HIGH-RISK PAPILLARY THYROID CARCINOMA.
*TIMING OF RADIOACTIVE IODINE THERAPY DOES NOT IMPACT OVERALL SURVIVAL IN HIGH-RISK PAPILLARY THYROID CARCINOMA.* Endocr Pract. 2016 Mar 28; Authors: Suman P, Wang CH, Abadin SS, Block R, Raghavan V, Moo-Young TA, Prinz RA, Winchester DJ Abstract OBJECTIVE: Post-thyroidectomy radioiodine (RAI) therapy is indicated for papillary thyroid carcinoma (PTC) with high-risk features. There is a variability in the timing of RAI therapy with no consensus. We analyzed the impact of the timing of initial RAI therapy on overall survival (OS) in PTC. METHODS: The National Cancer Data Base (NCDB... περισσότερα »
3D-2D Deformable Image Registration Using Feature-Based Nonuniform Meshes.
*3D-2D Deformable Image Registration Using Feature-Based Nonuniform Meshes.* Biomed Res Int. 2016;2016:4382854 Authors: Zhong Z, Guo X, Cai Y, Yang Y, Wang J, Jia X, Mao W Abstract By using prior information of planning CT images and feature-based nonuniform meshes, this paper demonstrates that volumetric images can be efficiently registered with a very small portion of 2D projection images of a Cone-Beam Computed Tomography (CBCT) scan. After a density field is computed based on the extracted feature edges from planning CT images, nonuniform tetrahedral meshes will be automatical... περισσότερα »
French validation of the Barcelona Music Reward Questionnaire.
*French validation of the Barcelona Music Reward Questionnaire.* PeerJ. 2016;4:e1760 Authors: Saliba J, Lorenzo-Seva U, Marco-Pallares J, Tillmann B, Zeitouni A, Lehmann A Abstract Background. The Barcelona Music Reward Questionnaire (BMRQ) questionnaire investigates the main facets of music experience that could explain the variance observed in how people experience reward associated with music. Currently, only English and Spanish versions of this questionnaire are available. The objective of this study is to validate a French version of the BMRQ. Methods. The original BMRQ was ...περισσότερα »
A Phase II Clinical Trial of Concurrent Helical Tomotherapy plus Cetuximab Followed by Adjuvant Chemotherapy with Cisplatin and Docetaxel for Locally Advanced Nasopharyngeal Carcinoma.
*A Phase II Clinical Trial of Concurrent Helical Tomotherapy plus Cetuximab Followed by Adjuvant Chemotherapy with Cisplatin and Docetaxel for Locally Advanced Nasopharyngeal Carcinoma.* Int J Biol Sci. 2016;12(4):446-453 Authors: Zhang X, Du L, Zhao F, Wang Q, Yang S, Ma L Abstract Purpose: The present clinical trial was designed to evaluate the efficacy and safety of concurrent helical tomotherapy (HT) with cetuximab followed by adjuvant chemotherapy with docetaxel and cisplatin (TP) in the treatment of patients with locoregionally advanced nasopharyngeal carcinoma. Materials a...περισσότερα »
The American College of Surgeons National Surgical Quality Improvement Program Surgical Risk Calculator Does Not Accurately Predict Risk of 30-Day Complications Among Patients Undergoing Microvascular Head and Neck Reconstruction.
*The American College of Surgeons National Surgical Quality Improvement Program Surgical Risk Calculator Does Not Accurately Predict Risk of 30-Day Complications Among Patients Undergoing Microvascular Head and Neck Reconstruction.* J Oral Maxillofac Surg. 2016 Mar 3; Authors: Arce K, Moore EJ, Lohse CM, Reiland MD, Yetzer JG, Ettinger KS Abstract PURPOSE: The American College of Surgeons (ACS) National Surgical Quality Improvement Program (NSQIP) Surgical Risk Calculator (SRC) is a novel universal risk calculator designed to aid in risk stratification of patients undergoing vari... περισσότερα »
Case Reports of Two Unusual Donor Site Complications of the Pectoralis Major Myocutaneous Flap and Literature Review.
*Case Reports of Two Unusual Donor Site Complications of the Pectoralis Major Myocutaneous Flap and Literature Review.* J Oral Maxillofac Surg. 2016 Mar 3; Authors: Kim B, Kaleem A, Zaid W Abstract The pectoralis major myocutaneous flap (PMMF) for head and neck reconstruction was first introduced by Ariyan in 1979. For many subsequent years, it was considered a workhorse flap and is still widely used for a wide range of head and neck reconstructions, especially in developing countries, owing to its ease of harvest, reliability, versatility, proximity to the head and neck region, ...περισσότερα »
Intraoperative Image Guidance Improves Outcomes in Complex Orbital Reconstruction by Novice Surgeons.
*Intraoperative Image Guidance Improves Outcomes in Complex Orbital Reconstruction by Novice Surgeons.* J Oral Maxillofac Surg. 2016 Mar 3; Authors: Davis KS, Vosler PS, Yu J, Wang EW Abstract PURPOSE: This study aims to describe the utility of surgical navigation in improving operative outcomes in complex orbital reconstruction by novice compared with experienced surgical trainees. MATERIALS AND METHODS: A randomized, controlled cadaveric study was conducted at the University of Pittsburgh School of Medicine with otolaryngology and ophthalmology residents and fellows. Participant... περισσότερα »
Radiation therapy (with or without neck surgery) for phenotypic human papillomavirus-associated oropharyngeal cancer.
*Radiation therapy (with or without neck surgery) for phenotypic human papillomavirus-associated oropharyngeal cancer.* Cancer. 2016 Mar 28; Authors: Garden AS, Fuller CD, Rosenthal DI, William WN, Gunn GB, Beadle BM, Johnson FM, Morrison WH, Phan J, Frank SJ, Kies MS, Sturgis EM Abstract BACKGROUND: Favorable outcomes for human papillomavirus-associated oropharyngeal cancer have led to interest in identifying a subgroup of patients with the lowest risk of disease recurrence after therapy. De-intensification of therapy for this group may result in survival outcomes that are simil... περισσότερα »
Treatment trends and survival effects of chemotherapy for hypopharyngeal cancer: Analysis of the National Cancer Data Base.
*Treatment trends and survival effects of chemotherapy for hypopharyngeal cancer: Analysis of the National Cancer Data Base.* Cancer. 2016 Mar 28; Authors: Kuo P, Sosa JA, Burtness BA, Husain ZA, Mehra S, Roman SA, Yarbrough WG, Judson BL Abstract BACKGROUND: The current study was performed to characterize trends and survival outcomes for chemotherapy in the definitive and adjuvant treatment of hypopharyngeal cancer in the United States. METHODS: A total of 16,248 adult patients diagnosed with primary hypopharyngeal cancer without distant metastases between 1998 and 2011 were ide... περισσότερα »
Retrograde intra-arterial chemotherapy and daily concurrent proton beam therapy for recurrent oral cavity squamous cell carcinoma: Analysis of therapeutic results in 46 cases.
*Retrograde intra-arterial chemotherapy and daily concurrent proton beam therapy for recurrent oral cavity squamous cell carcinoma: Analysis of therapeutic results in 46 cases.* Head Neck. 2016 Mar 28; Authors: Hayashi Y, Nakamura T, Mitsudo K, Yamaguchi H, Ono T, Azami Y, Takayama K, Suzuki M, Hatayama Y, Tsukiyama I, Hareyama M, Kikuchi Y, Fuwa N, Tohnai I Abstract BACKGROUND: The purpose of this study was to evaluate the efficacy and toxicities of proton beam therapy combined with intra-arterial infusion chemotherapy via superficial temporal and occipital arteries for recurren...περισσότερα »
The Role of Military Plastic Surgeons in the Management of Modern Combat Trauma: An Analysis of 645 Cases.
*The Role of Military Plastic Surgeons in the Management of Modern Combat Trauma: An Analysis of 645 Cases.* Plast Reconstr Surg. 2016 Apr;137(4):717e-724e Authors: Maitland L, Lawton G, Baden J, Cubison T, Rickard R, Kay A, Hettiaratchy S Abstract BACKGROUND: Plastic surgery has historically been linked to war. Between 2008 and the end of combat operations in Afghanistan in 2014, British military plastic surgeons formed part of the multinational military surgical team at the Role 3 Medical Treatment Facility, Camp Bastion, Helmand Province. The present study aimed to analyze the...περισσότερα »
Surgical Management of Obstructive Sleep Apnea.
*Surgical Management of Obstructive Sleep Apnea.* Plast Reconstr Surg. 2016 Apr;137(4):1263-1272 Authors: Tanna N, Smith BD, Zapanta PE, Karanetz I, Andrews BT, Urata MM, Bradley JP Abstract Surgical management of snoring and obstructive sleep apnea is indicated when a surgically correctable abnormality is believed to be the source of the problem. Many patients opt for surgical treatment after noninvasive forms of treatment have been proven ineffective or difficult to tolerate. With increasing frequency, functional rhinoplasty, septoplasty, turbinoplasty, palatal surgery, and ort...περισσότερα »
A Comparative Assessment of Three Formulations of Botulinum Toxin Type A for Facial Rhytides: A Systematic Review with Meta-Analyses.
*A Comparative Assessment of Three Formulations of Botulinum Toxin Type A for Facial Rhytides: A Systematic Review with Meta-Analyses.* Plast Reconstr Surg. 2016 Apr;137(4):1125-1140 Authors: Bonaparte JP, Ellis D, Quinn JG, Rabski J, Hutton B Abstract BACKGROUND: Three formulations of botulinum toxin are available for facial rhytides. It is unclear which formulation offers the greatest balance of benefits and harms. The objective of this study was to conduct a systematic review with meta-analyses to compare formulations of botulinum toxin for reduction of facial rhytides at the g... περισσότερα »
High-Resolution, Non-Invasive Imaging of Upper Vocal Tract Articulators Compatible with Human Brain Recordings.
*High-Resolution, Non-Invasive Imaging of Upper Vocal Tract Articulators Compatible with Human Brain Recordings.* PLoS One. 2016;11(3):e0151327 Authors: Bouchard KE, Conant DF, Anumanchipalli GK, Dichter B, Chaisanguanthum KS, Johnson K, Chang EF Abstract A complete neurobiological understanding of speech motor control requires determination of the relationship between simultaneously recorded neural activity and the kinematics of the lips, jaw, tongue, and larynx. Many speech articulators are internal to the vocal tract, and therefore simultaneously tracking the kinematics of all...περισσότερα »
Feasibility of comfortable and secure intubation achieved with the Disposcope endoscope or Macintosh laryngoscope for patients in whom glottis viewing is difficult.
[image: http:--http://ift.tt/1PDDTpj] Related Articles *Feasibility of comfortable and secure intubation achieved with the Disposcope endoscope or Macintosh laryngoscope for patients in whom glottis viewing is difficult.* Genet Mol Res. 2015;14(2):3694-701 Authors: Li XH, Sun Z, He LL Abstract We aimed to study the feasibility of a comfortable and secure intubation achieved with the Disposcope endoscope or Macintosh laryngoscope when glottis viewing is difficult. Forty adults scheduled for elective surgery under general anesthesia, in whom glottis viewing was difficult with the ... περισσότερα »
