Αρχειοθήκη ιστολογίου

Αλέξανδρος Γ. Σφακιανάκης
ΩτοΡινοΛαρυγγολόγος
Αναπαύσεως 5
Άγιος Νικόλαος Κρήτη 72100
2841026182
6032607174

Δευτέρα 7 Δεκεμβρίου 2015

OtoRhinoLaryngology & Medicine,New Articles,December 8th,2015,a


The treatment modalities and pain management of temporomandibular disorders

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 4 δευτερόλεπτα
Reported concepts for the treatment modalities and pain management of temporomandibular disorders: Background: Pain related to temporomandibular disorders (TMD) is a common problem in modern societies. The aim of the article is to present the concepts of TMD pain clinical management. Methods: A survey was performed using the PubMed, SCOPUS and CINAHL databases for documents published between 1994 and 2014. The following search keywords were selected using MeSH terms of the National Library of Medicine in combination: TMD pain, TMD, TMJ, TMJ disorders, occlusal splint, TMD physiothera... περισσότερα »

Horner’s syndrome and unilateral facial paresis

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 7 δευτερόλεπτα
in a goat: a case report: AbstractA 4-year-old, female Pakistani goat was referred to the veterinary teaching hospital for first pregnancy check up. At the time of presentation, the case was apparently healthy. Incidentally, the clinicians noticed the abnormality in the left eye. A precise ophthalmic examination revealed ptosis, entropion, nictitating membrane prolapse, enophthalmos, and miosis in the left eye, whereas the eyelids and pupil were normal on the right side. The left eye lacked palpebral reflex, and the menace response seemed to be decreased. Pupillary light reflex wa... περισσότερα »

Osteosarcoma compared to other high-grade primary bone sarcomas

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 7 δευτερόλεπτα
SATB2 expression is sensitive but may not be specific for osteosarcoma compared to other high-grade primary bone sarcomas: Abstract Aims Diagnosis of osteosarcoma, while important for eligibility in clinical trials and proper therapy, may be challenging when no bone or osteoid matrix is identified on biopsy. Therefore, other adjunct tests have been sought to help confirm the diagnosis. SATB2 has been shown as a reliable marker of osteoblastic differentiation. The aim of this study was to examine SATB2 expression in osteosarcomas and other primary bone sarcomas, to evaluate its diag... περισσότερα »

Use of Dexmedetomidine for Prophylactic Analgesia and Sedation in Patients With Delayed Extubation After Craniotomy: A Randomized Controlled Trial.

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 7 δευτερόλεπτα
Use of Dexmedetomidine for Prophylactic Analgesia and Sedation in Patients With Delayed Extubation After Craniotomy: A Randomized Controlled Trial.: Background: We conducted a randomized trial to evaluate the efficacy and safety of dexmedetomidine for prophylactic analgesia and sedation in patients with delayed extubation after craniotomy. Methods: From June 2012 to July 2014, 150 patients with delayed extubation after craniotomy were randomized 1:1 and were assigned to the dexmedetomidine group that received a continuous infusion of 0.6 [mu]g/kg/h (10 [mu]g/mL) or the control group ... περισσότερα »

Whole-mount pathology of breast lumpectomy specimens improves detection of tumour margins and focality

Alexandros G. SfakianakisστοΠαθολοΑνατομίαΠριν από 7 δευτερόλεπτα
[image: cover.gif?v=1&s=3694dc29810624c6fbc8ceb7] *Abstract* Aims Technical limitations in conventional pathologic evaluation of breast lumpectomy specimens may reduce diagnostic accuracy in assessment of margin and focality. A novel technique based on whole-mount serial sections enhances sampling while preserving specimen conformation and orientation. We compare assessment of focality and margin status using whole-mount serial sections versus simulated conventional sections in lumpectomies. Methods and Results Two pathologists interpreted whole-mount serial sections and simulat... περισσότερα »

SATB2 expression is sensitive but may not be specific for osteosarcoma compared to other high-grade primary bone sarcomas

Alexandros G. SfakianakisστοΠαθολοΑνατομίαΠριν από 7 δευτερόλεπτα
Abstract Aims Diagnosis of osteosarcoma, while important for eligibility in clinical trials and proper therapy, may be challenging when no bone or osteoid matrix is identified on biopsy. Therefore, other adjunct tests have been sought to help confirm the diagnosis. SATB2 has been shown as a reliable marker of osteoblastic differentiation. The aim of this study was to examine SATB2 expression in osteosarcomas and other primary bone sarcomas, to evaluate its diagnostic utility in discriminating osteogenic versus non-osteogenic sarcomas. Methods and Results Forty-eight pre-treated ... περισσότερα »

Issue Cover (December 2015)

Alexandros G. SfakianakisστοΝευρολογία κ' ΝευροχειρουργικήΠριν από 7 δευτερόλεπτα
[image: Thumbnail image of graphical abstract] *Cover Illustration: GAT-1 expression in GFAP-positive astrocytes from the suprachiasmatic nucleus (SCN).* SCN primary cell cultures were prepared under aseptic conditions from one-day rat pups and grown for one week. The cells were fixed and stained using antibodies to glial fibrillary acidic protein (GFAP, green) and the GABA transporter-1 (GAT-1, red). The nuclei were counter-stained with DAPI (blue). The confocal image shows GFAP-positive astrocytes with different morphologies that express GAT-1. *Eur. J. Neurosci.*, doi: 10.1111/e... περισσότερα »

HLA and Risk of Diffuse Large B-cell Lymphoma After Solid Organ Transplantation.

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 14 δευτερόλεπτα
HLA and Risk of Diffuse Large B-cell Lymphoma After Solid Organ Transplantation.: Background: Solid organ transplant recipients have heightened risk for diffuse large B-cell lymphoma (DLBCL). The role of donor-recipient HLA mismatch and recipient HLA type on DLBCL risk are not well established. Methods: We examined 172 231 kidney, heart, pancreas, and lung recipients transplanted in the United States between 1987 and 2010, including 902 with DLBCL. Incidence rate ratios (IRRs) were calculated using Poisson regression for DLBCL risk in relation to HLA mismatch, types, and zygosity, a...περισσότερα »

Giant and aggressive earlobe keloids

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 15 δευτερόλεπτα
Unusually giant and aggressive earlobe keloids – Two clinical reports via ScienceDirect Publication: Egyptian Journal of Ear, Nose, Throat and Allied Sciences Figures and tables 1. [image: Right side earlobe showing a giant keloid with an ulcer over the surface.] 2. [image: Microphotograph showing keloidal collagen with abundant fibroblasts.] 3. [image: Left side earlobe showing a gaint and lobulated keloid.] 4. [image: Microphotograph of keloid showing abnormally large dense, broad, glassy, ...] *Source:*Egyptian Journal of Ear, Nose, Throat and Allied Scie... περισσότερα »

Congenital mandibular epulis

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 15 δευτερόλεπτα
– A rare oral lesion in a newborn via ScienceDirect Publication: Egyptian Journal of Ear, Nose, Throat and Allied Sciences Figures and tables 1. [image: Oral mass seen upon delivering via caesarean section.] 2. [image: CT scan view of the lesion.] 3. [image: Image showing the location of tumour.] 4. [image: Image shows excision done using monopolar diathermy.] *Source:*Egyptian Journal of Ear, Nose, Throat and Allied Sciences, Volume 16, Issue 3 Author(s): Nurhani Yasmin Abdul Rahman, Hashimah Ismail, Irfan Mohamad, Suhaimi Yusof, Hazama Mohamad IntroductionCongenita... περισσότερα »

Parotid abscess; Salmonella enterica subsp. arizonae

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 15 δευτερόλεπτα
A rare cause of via ScienceDirect Publication: Egyptian Journal of Ear, Nose, Throat and Allied Sciences Figures and tables 1. [image: View of the right parotid abscess.] 2. [image: CT scan showing an abscess in the right parotid gland (white arrow).] *Source:*Egyptian Journal of Ear, Nose, Throat and Allied Sciences, Volume 16, Issue 3 Author(s): Hakan Kaya, Bülent Durdu, Arzu Karaman Koç, Yakup Yegin, Mustafa Çelik, Fatma Tülin Kayhan IntroductionSalmonella enterica subsp. arizonae is a common gut inhabitant of reptiles and snakes are the most common reservoir. The... περισσότερα »

Congenital cervical lymphangioma

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 15 δευτερόλεπτα
‘A huge congenital cervical lymphangioma’ – Case report with review of literature via ScienceDirect Publication: Egyptian Journal of Ear, Nose, Throat and Allied Sciences Figures and tables 1. [image: Clinical photograph of the newborn (a) front view and (b) lateral view; showing ...] 2. [image: CT scan neck with thorax (a) axial view, (b) sagittal view and (c) coronal view; ...] 3. [image: Intra-operative photographs; (a) thwart cervical incision. (b) Huge mass ...] 4. [image: Clinical photograph after 9months of follow up showing swelling over lower 1/3rd... περισσότερα »

Unilateral parotid gland swelling as the sole presenting symptom of acute lymphoblastic leukaemia

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 15 δευτερόλεπτα
in children via ScienceDirect Publication: Egyptian Journal of Ear, Nose, Throat and Allied Sciences Figures and tables 1. [image: Diffuse atypical lymphoid cells with occasional residual salivary ducts ...] 2. [image: Diffuse atypical lymphoid cells consisting of small to medium cells with ...] 3. [image: The atypical lymphoid cells are positive for Pax 5.] 4. [image: The atypical lymphoid cells are positive for Tdt.] *Source:*Egyptian Journal of Ear, Nose, Throat and Allied Sciences, Volume 16, Issue 3 Author(s): Yatiee Swany Lahuri, Irfan Mohamad, Mohd Iszu... περισσότερα »

Sinonasal amelanotic malignant melanoma

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 20 δευτερόλεπτα
– A diagnostic dilemma via ScienceDirect Publication: Egyptian Journal of Ear, Nose, Throat and Allied Sciences Figures and tables 1. [image: Anterior rhinoscopy showing a reddish polypoidal mass in the left nasal cavity.] 2. [image: Computed tomographic scan of the nose and PNS showing homogenous soft tissue ...] 3. [image: Photomicrograph showing tumor cells moderately pleomorphic, arranged in sheets ...] *Source:*Egyptian Journal of Ear, Nose, Throat and Allied Sciences, Volume 16, Issue 3 Author(s): Roshan Verma, K.P. Lokesh, Kirti Gupta, Naresh K. Panda ... περισσότερα »

Cholesteatoma associated with squamous cell carcinoma of the external auditory canal

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 21 δευτερόλεπτα
: Case report and literature review via ScienceDirect Publication: Egyptian Journal of Ear, Nose, Throat and Allied Sciences Figures and tables 1. [image: Tonal audiometry showing mixed hearing loss with a mean ABG of 40dB.] 2. [image: Coronal (a and b) and axial (c and d) CT scan of the right temporal bone showing ...] 3. [image: Axial T1-weighted (a), Axial Gadolinium enhanced T1-weighted (b), Axial ...] 4. [image: Histological section (HES stain) showing polygonal tumor cells with clear ...] 5. [image: Operative specimen with en-bloc resection of the o... περισσότερα »

Expansile ancient schwannoma of the nose and paranasal sinuses

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 21 δευτερόλεπτα
A case of via ScienceDirect Publication: Egyptian Journal of Ear, Nose, Throat and Allied Sciences Figures and tables 1. [image: CT scan of the nose and paranasal sinuses showing soft tissue attenuation in the ...] 2. [image: Intra-operative endoscopic photograph showing the mass in the left nasal cavity.] 3. [image: Histopathological picture of the excised specimen showing a spindle-cell tumour ...] 4. [image: Post-operative endoscopic photograph, after one month showing healthy nasal ...] *Source:*Egyptian Journal of Ear, Nose, Throat and Allied Scien... περισσότερα »

Septoplasty on the acoustic parameters of voice

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 21 δευτερόλεπτα
Effects of via ScienceDirect Publication: Egyptian Journal of Ear, Nose, Throat and Allied Sciences *Source:*Egyptian Journal of Ear, Nose, Throat and Allied Sciences, Volume 16, Issue 3 Author(s): Vijayalakshmi Subramaniam, Raniya Yoonus, Manjunath Narra ObjectivesTo study the effects of nasal septal deviation and the effects of septoplasty on voice using acoustic analysis.Study designProspective case–control study.SettingYenepoya Medical College Hospital, a tertiary referral hospital.MethodsA total of 45 subjects comprising 15 patients (study group) who underwent septoplasty and 3...περισσότερα »

Laser posterior cordotomy and vocal cord lateralization

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 21 δευτερόλεπτα
A comparative study of via ScienceDirect Publication: Egyptian Journal of Ear, Nose, Throat and Allied Sciences Publication date: November 2015 *Source:*Egyptian Journal of Ear, Nose, Throat and Allied Sciences, Volume 16, Issue 3 Author(s): Raghavendra Rao, Vijendra Shenoy, Vishnu Prasad, Panduranga Kamath, P. Hazarika, Kanishka S. Rao IntroductionThe treatment of bilateral vocal cord paralysis continues to be a challenge to the otolaryngologist, head and neck surgeon even today. Numerous surgical procedures have been proposed to improve the patient’s airway insufficiency without le...περισσότερα »

High resolution multislice CT scan in otosclerosis

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 23 δευτερόλεπτα
Role of via ScienceDirect Publication: Egyptian Journal of Ear, Nose, Throat and Allied Sciences Publication date: November 2015 *Source:*Egyptian Journal of Ear, Nose, Throat and Allied Sciences, Volume 16, Issue 3 Author(s): Atef EL Maraghy, Wael Aboelwafa, Mohammed Abdel Monem, Alaa Abdul Ghany, Hany Sheref, Ahmed Mahmoud This prospective study was carried out to assess the radiological findings in patients with otosclerosis using high resolution multislice CT scan and to correlate these findings with audiological findings in those patients. This study was done at Al Azhar Univers...περισσότερα »

British Journal of Oral and Maxillofacial Surgery

Αλέξανδρος ΣφακιανάκηςστοMedicine by Sfakianakis G. AlexandrosΠριν από 23 δευτερόλεπτα
Association between p53 status, human papillomavirus infection, and overall survival in advanced oral cancer after resection and combination systemic treatment Publication date: Available online 6 December 2015 *Source:*British Journal of Oral and Maxillofacial Surgery Author(s): Tommaso Cutilli, Pietro Leocata, Vincenza Dolo, Emma Altobelli Our previous study on 75 cases of advanced oral squamous cell carcinomas (SCC) treated by neoadjuvant chemotherapy, radical surgery, and radiotherapy showed that overexpression of p53 of more than 50% indicated a strong probability of genetic mut...περισσότερα »

Transconjunctival and lateral canthotomy with modified endaural approaches in midface osteogenic distraction

Αλέξανδρος ΣφακιανάκηςστοMedicine by Sfakianakis G. AlexandrosΠριν από 25 δευτερόλεπτα
Combination of via British Journal of Oral and Maxillofacial Surgery [image: The transconjunctival with lateral canthotomy approach, and the lateral orbital ...] [image: Diagram showing surgical approaches (green lines), Le Fort III osteotomies (red ...] [image: (A) Postoperative picture showing osteogenic distractors in place and adequate ...] [image: Preoperative and postoperative pictures showing changes after distraction and ...] *Source:*British Journal of Oral and Maxillofacial Surgery Author(s): Humberto Fernández-Olarte, Andrés Gómez-Delgado, Daniel Varón-Cardona, Sergio Truj... περισσότερα »

The antimicrobial effect of gaseous ozone compared to conventional methods against Enterococcus faecalis

Αλέξανδρος ΣφακιανάκηςστοMedicine by Sfakianakis G. AlexandrosΠριν από 25 δευτερόλεπτα
Effect of gaseous ozone on Enterococcus faecalis biofilm–an in vitro study: Abstract ObjectivesThe aim of this study was to evaluate the antimicrobial effect of gaseous ozone compared to conventional methods against *Enterococcus faecalis.* Materials and methodsOne hundred twenty-five teeth were infected by *E. faecalis* and were incubated for 72 h to form biofilm. Teeth were distributed among five groups. In the first group, ozone was used; in the second group, teeth were rinsed with 20 % ethylenediaminetetraacetic acid (EDTA); in the third group, with 3 % sodium hypochlorite ... περισσότερα »

The impact of malocclusions on oral health-related quality of life in children

Αλέξανδρος ΣφακιανάκηςστοMedicine by Sfakianakis G. AlexandrosΠριν από 25 δευτερόλεπτα
The impact of malocclusions on oral health-related quality of life in children—a systematic review and meta-analysis: Abstract IntroductionA limited amount of systematic literature reviews on the association between malocclusions and oral health-related quality of life (OHRQOL) summarize inconclusive results. Therefore, we conduct a systematic review and meta-analysis on the association of malocclusions with OHRQOL in children. MethodsRelevant studies were identified in Pubmed, Embase, Cochrane, Google Scholar and other databases. All studies with data on malocclusions or ortho...περισσότερα »

Factors affecting survival following self-inflicted head and neck gunshot wounds: a single-centre retrospective review

Αλέξανδρος ΣφακιανάκηςστοMedicine by Sfakianakis G. AlexandrosΠριν από 25 δευτερόλεπτα
Factors affecting survival following self-inflicted head and neck gunshot wounds: a single-centre retrospective review: Abstract Self-inflicted head and neck gunshot wounds are a common modality of suicide in the USA. This study reviewed all self-inflicted head and neck gunshot wound patients with complete records (*n* = 157) treated at a tertiary centre between 2002 and 2012 inclusive. The associations between mortality and patient/clinical variables were evaluated with the *χ*2 test or Fisher's exact test for statistical difference testing. Outcomes recorded were death (*n* = 9... περισσότερα »

Long-term patterns of relapse and survival following definitive intensity-modulated radiotherapy for non-endemic nasopharyngeal carcinoma

Αλέξανδρος ΣφακιανάκηςστοMedicine by Sfakianakis G. AlexandrosΠριν από 25 δευτερόλεπτα
Long-term patterns of relapse and survival following definitive intensity-modulated radiotherapy for non-endemic nasopharyngeal carcinoma: Intensity-modulated radiotherapy has developed into the standard definitive treatment for nasopharyngeal carcinoma over the past 15years, in both the United States and in Asia, where Epstein-Barr virus-related non-keratinizing carcinomas of the nasopharynx are endemic [1,2]. Three randomized trials have compared IMRT to conventional radiotherapy in the treatment of NPC [3–5]. Although local control rates with IMRT have improved with the advent an... περισσότερα »

MicroRNA-31 upregulation predicts increased risk of progression of oral potentially malignant disorder

Αλέξανδρος ΣφακιανάκηςστοMedicine by Sfakianakis G. AlexandrosΠριν από 25 δευτερόλεπτα
MicroRNA-31 upregulation predicts increased risk of progression of oral potentially malignant disorder: Oral squamous cell carcinoma (OSCC), which accounts for two-thirds of head and neck squamous cell carcinoma (HNSCC), is one of the most prevalent cancers worldwide. OSCC typically develops from oral potentially malignant disorder (OPMD) and is attributed to smoking, betel nut or tobacco chewing, and HPV infection. The most common type of OPMD is oral leukoplakia that histopathologically presents as hyperkeratosis, epithelial hyperplasia, or dysplasia. High-grade epithelial dysplas...περισσότερα »

Single-Dose of Submucosal Injection of Dexamethasone Affects the Post Operative QOL

Αλέξανδρος ΣφακιανάκηςστοMedicine by Sfakianakis G. AlexandrosΠριν από 25 δευτερόλεπτα
Single-Dose of Submucosal Injection of Dexamethasone Affects the Post Operative Quality of Life After Third Molar Surgery: Abstract IntroductionThird molar surgery (TMS) became a routine, safe office procedure with generally predictable outcomes and relative low cost. It affects quality of life (QOL) of patients by causing considerable pain, swelling and trismus; by changing what people eat, their speech in the first few days after surgery. The purpose of the present study was to improve QOL of patient after lower TMS by injecting single dose 8 mg submucosal dexamethasone. Mate... περισσότερα »

Tracheotomietechniken

Αλέξανδρος ΣφακιανάκηςστοMedicine by Sfakianakis G. AlexandrosΠριν από 25 δευτερόλεπτα
Tracheotomietechniken: ZusammenfassungDurch die flächendeckende Etablierung moderner Verfahren hat sich die Tracheotomie zu einem Routineeingriff in der Intensivmedizin entwickelt. Durch die Tracheotomie können negative Effekte einer prolongierten translaryngealen Intubation auf die Larynx- und Trachealschleimhaut bis hin zur Trachealstenose vermindert werden. Weiterhin wird die Langzeitbeatmung bei kritisch kranken Patienten erleichtert. Es gibt allerdings keine eindeutige Evidenz über den optimalen Zeitpunkt der Tracheotomie bei Intensivpatienten. Für die sichere und erfolgreiche...περισσότερα »

Many faces of REM sleep behavior disorder

Αλέξανδρος ΣφακιανάκηςστοMedicine by Sfakianakis G. AlexandrosΠριν από 25 δευτερόλεπτα
Many faces of REM sleep behavior disorder: an editorial: Since the first description of rapid-eye movement sleep behavior disorder (RBD) as a REM parasomnia in 19861 the concept of RBD has been evolving. The initial concept of RBD being an idiopathic parasomnia began to change since the investigators who originally described this entity observed that 38% of their original cohort of 29 idiopathic RBD (iRBD) patients developed signs and symptoms of Parkinson's disease (PD) 10 years after the inital description.2 Since this publication the concept shifted dramatically from idiopathic t... περισσότερα »

The Journal of the Acoustical Society of America

Αλέξανδρος ΣφακιανάκηςστοMedicine by Sfakianakis G. AlexandrosΠριν από 25 δευτερόλεπτα
Airgun inter-pulse noise field during a seismic survey in an Arctic ultra shallow marine environment seismic Low-frequency sound level in the Southern Indian Ocean sound Coding pitch differences in voiceless fricatives: Whispered relative to normal speech Intonation Underdetermined reverberant acoustic source separation using weighted full-rank nonnegative tensor models K Effects of voice style, noise level, and acoustic feedback on objective and subjective voice evaluations room acoustic Enhancing cell kill in vitro from hyperthermia through pre-sensitizing with ultrasound-stimulated ... περισσότερα »

Mastoid Dimensions in Children and Young Adults: Consequences for the Geometry of Transcutaneous Bone-Conduction Implants.

Αλέξανδρος ΣφακιανάκηςστοMedicine by Sfakianakis G. AlexandrosΠριν από 25 δευτερόλεπτα
Mastoid Dimensions in Children and Young Adults: Consequences for the Geometry of Transcutaneous Bone-Conduction Implants.: Objectives: Bone-conduction implants (BCI) are available for adults and children who are aged 5 years or more. Because a transcutaneous bone-conduction implant introduced in 2013 does not completely fit into all adult mastoids, we investigated mastoid dimensions and the possibility of fitting the implant in children. Design: Computed tomography scans of 151 mastoids from 80 children and young adolescents from the age of 5 months to 20 years and 52 control masto...περισσότερα »

Audible Tinnitus

Αλέξανδρος ΣφακιανάκηςστοMedicine by Sfakianakis G. AlexandrosΠριν από 25 δευτερόλεπτα
Audible 2 Tinnitus Review: Tinnitus, also known as ringing of the ears, can be one of the most frustrating physical problems a person can deal with in their lives. With doctors having few answers as to what causes it and why it seems to come and go at times, patients with this condition can get frustrated to say the least. As with most other physical problems people face, there are those who claim to offer solutions to their problems, and tinnitus is no exception. One of the latest products to come along claiming to have the answers to combat tinnitus is the Audible 2, a type of hea... περισσότερα »

Age and gender differences in children and adolescents’ attitudes toward noise

Αλέξανδρος ΣφακιανάκηςστοMedicine by Sfakianakis G. AlexandrosΠριν από 25 δευτερόλεπτα
Age and gender differences in children and adolescents’ attitudes toward noise Abstract *Objective*: Most school-aged children experience exposure to hazardous sound levels via high-risk noise activities (e.g. loud music/concerts, firearms). Little information exists regarding factors influencing pediatric engagement in these activities and use of hearing protection devices. This study explores effects of age, gender, and attitudes toward noise on participation in acoustic risk-taking behaviors and hearing conservation practices in children and adolescents. *Design*: Cross-secti... περισσότερα »

Prevalence and risk factors for reduced sound tolerance (hyperacusis) in children

Αλέξανδρος ΣφακιανάκηςστοMedicine by Sfakianakis G. AlexandrosΠριν από 25 δευτερόλεπτα
Prevalence and risk factors for reduced sound tolerance (hyperacusis) in children Abstract *Objective*: To estimate the prevalence of reduced sound tolerance (hyperacusis) in a UK population of 11-year-old children and examine the association of early life and auditory risk factors with report of hyperacusis. *Design*: A prospective UK population-based study. *Study sample*: A total of 7097 eleven-year-old children within the Avon longitudinal study of parents and children (ALSPAC) were asked about sound tolerance; hearing and middle-ear function was measured using audiometry, o... περισσότερα »

Effect of Triple Combination of Induction, Concurrent and Adjuvant Chemotherapy in High Risk Nasopharyngeal Carcinoma

Αλέξανδρος ΣφακιανάκηςστοMedicine by Sfakianakis G. AlexandrosΠριν από 25 δευτερόλεπτα
Effect of Triple Combination of Induction, Concurrent and Adjuvant Chemotherapy in High Risk Nasopharyngeal Carcinoma: *Condition*: Nasopharyngeal Carcinoma *Interventions*: Drug: Cisplatin 1; Drug: Cisplatin 2; Drug: Docetaxel; Drug: Xeloda; Radiation: Intensity-modulated radiotherapy *Sponsors*: Sun Yat-sen University; Affiliated Tumor Hospital of Guangzhou Medical University; The First Affiliated Hospital of Guangzhou Medical University; The First Affiliated Hospital of Guangdong Pharmaceutical University ArmsAssigned InterventionsExperimental: IC plus CC ... περισσότερα »

Exercise Protocol of Multisensory Rehabilitation in Treatment of the Complaints Vestibular: Clinical Trial Random

Αλέξανδρος ΣφακιανάκηςστοMedicine by Sfakianakis G. AlexandrosΠριν από 25 δευτερόλεπτα
Exercise Protocol of Multisensory Rehabilitation in Treatment of the Complaints Vestibular: Clinical Trial Random: *Condition*: Vestibular Diseases *Interventions*: Other: Intervention Group (IG); Other: Control Group (CG) *Sponsor*: Viviane de Souza Pinho Costa Vertigo, dizziness and imbalance are the main symptoms of vestibular dysfunction. They can lead to physical consequences, such as the reduction of postural control and falls, psychological and / or psychiatric consequences such as anxiety and depression, panic and cognitive changes, especially in the elderly. It ... περισσότερα »

Bullet in the Parapharyngeal Space

Αλέξανδρος ΣφακιανάκηςστοMedicine by Sfakianakis G. AlexandrosΠριν από 25 δευτερόλεπτα
Ballistic Reconstruction of a Migrating Bullet in the Parapharyngeal Space: A 21-year-old male suffering from severe throat pain after being hit by a bullet in Syria claimed that he was shot through his eye and that the bullet subsequently descended behind his throat. Even though the first medical report stated that this course is implausible, meticulous workup provided evidence that the bullet might have entered the parapharyngeal space in a more cranial position than the one it was found eight months later. Our case highlights that bullets are able to move within the body, renderi... περισσότερα »

Head and neck adenoid cystic carcinoma

Αλέξανδρος ΣφακιανάκηςστοMedicine by Sfakianakis G. AlexandrosΠριν από 25 δευτερόλεπτα
: A prospective multicenter REFCOR study of 95 cases via European Annals of Otorhinolaryngology, Head and Neck Diseases *Source:*European Annals of Otorhinolaryngology, Head and Neck Diseases Author(s): M. Meyers, B. Granger, P. Herman, F. Janot, R. Garrel, N. Fakhry, G. Poissonnet, B. Baujat ObjectivesTo describe the clinical, histological and therapeutic characteristics of a prospective multicenter series of 95 head and neck adenoid cystic carcinoma patients, and to determine any prognostic factors for disease-free survival.Patients and methodsNinety-five patients with adenoid cysti...περισσότερα »

Nocardia nova sphenoid sinusitis and infratemporal fossa abscess

Αλέξανδρος ΣφακιανάκηςστοMedicine by Sfakianakis G. AlexandrosΠριν από 25 δευτερόλεπτα
Nocardia nova sphenoid sinusitis and infratemporal fossa abscess via European Annals of Otorhinolaryngology, Head and Neck Diseases Figures and tables 1. [image: CT scan confirming left ethmoid and sphenoid sinusitis.] 2. [image: a. Sinus CT scan showing an abscess in the left pterygoid muscles; b. CT scan, ...] *Source:*European Annals of Otorhinolaryngology, Head and Neck Diseases Author(s): A. Giordano, M. Cohen-Salmon, B. Joly, C. Maffiolo IntroductionNocardia sinusitis is exceptional, as a Medline search revealed only one published case. The authors report a case of ... περισσότερα »

Primary immune-mediated sensorineural hearing loss

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 26 δευτερόλεπτα
Intra-tympanic corticosteroid for the treatment of via ScienceDirect Publication: Egyptian Journal of Ear, Nose, Throat and Allied Sciences *Source:*Egyptian Journal of Ear, Nose, Throat and Allied Sciences, Volume 16, Issue 3 Author(s): Mohamed A. Hamid, Ossama A. Hamid, Somia Tawfik, Sherif K. Mohamed, Ihab Kamal IntroductionDevelopment of sensorineural hearing loss [SNHL] leads to severe handicap that affects patient’s job, home and life. Therefore, otologists should diagnose potentially treatable disorders to improve and/or even stabilize hearing.Aim of workEvaluation of intra-t...περισσότερα »

Crooked nose

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 26 δευτερόλεπτα
: The asymmetric face via ScienceDirect Publication: Egyptian Journal of Ear, Nose, Throat and Allied Sciences Figures and tables 1. [image: G=Glabella, C=midpoint of the upper lip, and T=nasal tip defining point. (Left) ...] 2. [image: (Left) Female patient with crooked nose I-shaped (linear) deviation with ...] 3. Table 1 4. [image: G=Glabella, E=maximum angle of deviation, and T=nasal tip defining point. (Left) ...] 5. Table 2 6. [image: G=Glabella, E=maximum angle of deviation, T=nasal tip defining point, A=cephalic ...] *Source:*Egypti... περισσότερα »

Invasive fungal infections of face

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 26 δευτερόλεπτα
– A diagnostic challenge: Case series and review via ScienceDirect Publication: Egyptian Journal of Ear, Nose, Throat and Allied Sciences Figures and tables 1. [image: (a) Preop photograph of patient showing redness and diffuse oedema of the right ...] 2. [image: (a) Preop photograph of patient showing diffuse swelling over the dorsum of the ...] 3. [image: (a) Preop photograph of patient showing diffuse 5×3cm firm, slightly tender ...] *Source:*Egyptian Journal of Ear, Nose, Throat and Allied Sciences, Volume 16, Issue 3 Author(s): Roshan K. Verma, Sourabha ... περισσότερα »

Batten graft septoplasty

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 28 δευτερόλεπτα
: Evaluation of a preferred technique via ScienceDirect Publication: Egyptian Journal of Ear, Nose, Throat and Allied Sciences *Source:*Egyptian Journal of Ear, Nose, Throat and Allied Sciences, Volume 16, Issue 3 Author(s): Wael Khamis Hussein, Remon Bazak Figures and tables 1. [image: Female patient performing with crocked nose. This is the first step in which the ...] 2. [image: The upper lateral cartilage is separated from the nasal septum. The severely ...] 3. [image: (A) Lateral view of the same patient after removal of the central deviation and ...] 4. ... περισσότερα »

Combining polydioxanone plate, conchal cartilage interpositional graft and rotation flaps for repair of septal perforation

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 28 δευτερόλεπτα
Combining polydioxanone plate, conchal cartilage interpositional graft and rotation flaps for repair of septal perforation via ScienceDirect Publication: Egyptian Journal of Ear, Nose, Throat and Allied Sciences *Source:*Egyptian Journal of Ear, Nose, Throat and Allied Sciences, Volume 16, Issue 3 Author(s): Hatem M. Hassan, Sherif K. Mohamed, Ameen Z. Alherabi Figures and tables 1. [image: Pre operative endoscopic view at septal perforation.] 2. [image: After insertion of the PDS foil, the mucosal flap is elevated and rested at the ...] 3. [image: The flap is sutured i... περισσότερα »

Variability in Postarrest Targeted Temperature Management Practice: Implications of the 2015 Guidelines

Alexandros G. SfakianakisστοΘεραπείαΠριν από 28 δευτερόλεπτα
Therapeutic Hypothermia and Temperature Management Dec 2015, Vol. 5, No. 4: 184-187. from Pharmacology via ola Kala on Inoreader http://ift.tt/1M0jKaU via IFTTT

Variability in Postarrest Targeted Temperature Management Practice: Implications of the 2015 Guidelines

Alexandros G. SfakianakisστοΘεραπείαΠριν από 28 δευτερόλεπτα
Therapeutic Hypothermia and Temperature Management Dec 2015, Vol. 5, No. 4: 184-187. from Pharmacology via ola Kala on Inoreader http://ift.tt/1M0jKaU via IFTTT

Post-septal orbital complications of acute bacterial rhinosinusitis

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 29 δευτερόλεπτα
: Endoscopic anatomical considerations via ScienceDirect Publication: Egyptian Journal of Ear, Nose, Throat and Allied Sciences *Source:*Egyptian Journal of Ear, Nose, Throat and Allied Sciences, Volume 16, Issue 3 Author(s): Ahmed A. Ibrahim, Wael K.A. Hussein, Ahmed A. Omran Figures and tables 1. [image: (a, b) 6year old male patient suffering from orbital cellulites associated with ...] 2. [image: Orbital subperiosteal abscess with extensive lid abscess, (a) CT coronal bone ...] 3. [image: (a−c) Two year old male child patient with right medial subperiosteal a... περισσότερα »

Transconjunctival and lateral canthotomy with modified endaural approaches in midface osteogenic distraction

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 29 δευτερόλεπτα
Combination of via British Journal of Oral and Maxillofacial Surgery [image: The transconjunctival with lateral canthotomy approach, and the lateral orbital ...] [image: Diagram showing surgical approaches (green lines), Le Fort III osteotomies (red ...] [image: (A) Postoperative picture showing osteogenic distractors in place and adequate ...] [image: Preoperative and postoperative pictures showing changes after distraction and ...] *Source:*British Journal of Oral and Maxillofacial Surgery Author(s): Humberto Fernández-Olarte, Andrés Gómez-Delgado, Daniel Varón-Cardona, Sergio Truj... περισσότερα »

British Journal of Oral and Maxillofacial Surgery

Alexandros G. SfakianakisστοOroFacial Medicine by Alexandros G.SfakianakisΠριν από 32 δευτερόλεπτα
Association between p53 status, human papillomavirus infection, and overall survival in advanced oral cancer after resection and combination systemic treatment Publication date: Available online 6 December 2015 *Source:*British Journal of Oral and Maxillofacial Surgery Author(s): Tommaso Cutilli, Pietro Leocata, Vincenza Dolo, Emma Altobelli Our previous study on 75 cases of advanced oral squamous cell carcinomas (SCC) treated by neoadjuvant chemotherapy, radical surgery, and radiotherapy showed that overexpression of p53 of more than 50% indicated a strong probability of genetic mut...περισσότερα »

The antimicrobial effect of gaseous ozone compared to conventional methods against Enterococcus faecalis

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 38 δευτερόλεπτα
Effect of gaseous ozone on Enterococcus faecalis biofilm–an in vitro study: Abstract ObjectivesThe aim of this study was to evaluate the antimicrobial effect of gaseous ozone compared to conventional methods against *Enterococcus faecalis.* Materials and methodsOne hundred twenty-five teeth were infected by *E. faecalis* and were incubated for 72 h to form biofilm. Teeth were distributed among five groups. In the first group, ozone was used; in the second group, teeth were rinsed with 20 % ethylenediaminetetraacetic acid (EDTA); in the third group, with 3 % sodium hypochlorite... περισσότερα »

The impact of malocclusions on oral health-related quality of life in children

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 38 δευτερόλεπτα
The impact of malocclusions on oral health-related quality of life in children—a systematic review and meta-analysis: Abstract IntroductionA limited amount of systematic literature reviews on the association between malocclusions and oral health-related quality of life (OHRQOL) summarize inconclusive results. Therefore, we conduct a systematic review and meta-analysis on the association of malocclusions with OHRQOL in children. MethodsRelevant studies were identified in Pubmed, Embase, Cochrane, Google Scholar and other databases. All studies with data on malocclusions or orth...περισσότερα »

Factors affecting survival following self-inflicted head and neck gunshot wounds: a single-centre retrospective review

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 38 δευτερόλεπτα
Factors affecting survival following self-inflicted head and neck gunshot wounds: a single-centre retrospective review: Abstract Self-inflicted head and neck gunshot wounds are a common modality of suicide in the USA. This study reviewed all self-inflicted head and neck gunshot wound patients with complete records (*n* = 157) treated at a tertiary centre between 2002 and 2012 inclusive. The associations between mortality and patient/clinical variables were evaluated with the *χ*2 test or Fisher's exact test for statistical difference testing. Outcomes recorded were death (*n* = ... περισσότερα »

Long-term patterns of relapse and survival following definitive intensity-modulated radiotherapy for non-endemic nasopharyngeal carcinoma

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 40 δευτερόλεπτα
Long-term patterns of relapse and survival following definitive intensity-modulated radiotherapy for non-endemic nasopharyngeal carcinoma: Intensity-modulated radiotherapy has developed into the standard definitive treatment for nasopharyngeal carcinoma over the past 15years, in both the United States and in Asia, where Epstein-Barr virus-related non-keratinizing carcinomas of the nasopharynx are endemic [1,2]. Three randomized trials have compared IMRT to conventional radiotherapy in the treatment of NPC [3–5]. Although local control rates with IMRT have improved with the advent an... περισσότερα »

MicroRNA-31 upregulation predicts increased risk of progression of oral potentially malignant disorder

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 40 δευτερόλεπτα
MicroRNA-31 upregulation predicts increased risk of progression of oral potentially malignant disorder: Oral squamous cell carcinoma (OSCC), which accounts for two-thirds of head and neck squamous cell carcinoma (HNSCC), is one of the most prevalent cancers worldwide. OSCC typically develops from oral potentially malignant disorder (OPMD) and is attributed to smoking, betel nut or tobacco chewing, and HPV infection. The most common type of OPMD is oral leukoplakia that histopathologically presents as hyperkeratosis, epithelial hyperplasia, or dysplasia. High-grade epithelial dysplas...περισσότερα »

Sichere radiologische Diagnostik und Therapie bei Dialysepatienten

Alexandros G. SfakianakisστοΝευρολογία κ' ΝευροχειρουργικήΠριν από 40 δευτερόλεπτα
Sichere radiologische Diagnostik und Therapie bei Dialysepatienten: Zusammenfassung HintergrundAufgrund der steigenden Lebenserwartung und multiplen Komorbiditäten von Dialysepatienten kommt einer sicheren radiologischen Diagnostik und Therapie eine entscheidende Bedeutung zu. FragestellungAnalyse von radiologischen Sicherheitsaspekten bei der Diagnostik und Therapie dysfunktionaler Dialyseshunts. ErgebnisseSicherheitsaspekte der radiologischen Diagnostik und Therapie bei Dialysepatienten beinhalten den Einsatz von potenziell nephrotoxischen oder gadoliniumhaltigen Kontrastm...περισσότερα »

CADASIL: MRI may be normal in the fourth decade of life - a case report

Alexandros G. SfakianakisστοΝευρολογία κ' ΝευροχειρουργικήΠριν από 40 δευτερόλεπτα
CADASIL: MRI may be normal in the fourth decade of life - a case report: Background Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) manifests by migraine with aura, cerebral ischemic events, mood disturbances and dementia. Brain MRI lesions typically precede the symptoms from 10 to 15 years and previous evidence showed all CADASIL patients above 35 years old have an abnormal MRI, supporting the clinical diagnosis. Case results We present a 37-year-old female patient with migraine without aura, a family history of CADASIL, normal... περισσότερα »

Integrated multidisciplinary care of headache disorders

Alexandros G. SfakianakisστοΝευρολογία κ' ΝευροχειρουργικήΠριν από 40 δευτερόλεπτα
Integrated multidisciplinary care of headache disorders: A narrative review: Background Recent evidence shows that multidisciplinary treatment is effective in chronic pain syndromes, especially in headache disorders. Aim The aim of this review is to summarize current knowledge on integrative care concepts in headache patients regarding the optimal and necessary treatment parts, optimal duration and setting. Methods We present a narrative review reporting current literature and personal experience. Results and conclusion Based on current knowledge, multidisciplinary treatment pro...περισσότερα »

Deep brain stimulation in headache

Alexandros G. SfakianakisστοΝευρολογία κ' ΝευροχειρουργικήΠριν από 40 δευτερόλεπτα
Deep brain stimulation in headache: *Background:* Deep brain stimulation of the posterior hypothalamic area was first introduced in 2000 to treat drug-refractory chronic cluster headache (CH). *Findings:* So far, hypothalamic stimulation has been employed in 79 patients suffering from various forms of intractable short-lasting unilateral headache forms, mainly trigeminal autonomic cephalalgias. The majority were (88.6%) chronic CH, including one patient who suffered from symptomatic chronic CH-like attacks; the remaining were short-lasting unilateral neuralgiform headache attacks w...περισσότερα »

Prevalence and characteristics of migraine in CADASIL

Alexandros G. SfakianakisστοΝευρολογία κ' ΝευροχειρουργικήΠριν από 40 δευτερόλεπτα
Prevalence and characteristics of migraine in CADASIL: Background and objective Migraine with aura (MA) is a major symptom of cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL). We assessed the spectrum of migraine symptoms and their potential correlates in a large prospective cohort of CADASIL individuals. Methods A standardized questionnaire was used in 378 CADASIL patients for assessing headache symptoms, trigger factors, age at first attack, frequency of attacks and associated symptoms. MRI lesions and brain atrophy were quanti... περισσότερα »

Familial limb pain and migraine

Alexandros G. SfakianakisστοΝευρολογία κ' ΝευροχειρουργικήΠριν από 40 δευτερόλεπτα
Familial limb pain and migraine: 8-year follow-up of four generations: Background Migraine limb pain may be under-recognized in adults and children. There is little information about familial forms of this disorder. Objectives To describe the clinical and inheritance patterns of familial migraine limb pain over four generations and to review the evidence for limb pain as a manifestation of migraine. Methods Prospective clinical and pedigree analysis with an 8-year follow-up of 27 family members. Results Eight members of the family had benign recurrent limb pain associated with ... περισσότερα »

Surgical treatment of acoustic neuroma: Outcomes and indications

Alexandros G. SfakianakisστοΘεραπείαΠριν από 40 δευτερόλεπτα
Publication date: Available online 7 December 2015 *Source:*Reports of Practical Oncology & Radiotherapy Author(s): Elisabetta Zanoletti, Chiara Faccioli, Alessandro Martini AimSurgery for acoustic neuroma has developed over the years with a gradual improvement in outcome. The goal of surgery should be cure of the disease and a low morbidity, preserving facial nerve function – and hearing, too, whenever feasible (i.e. in small tumors). The most appropriate approach must be decided case by case.BackgroundResults of microsurgery remain heterogeneous, however, probably due to the differ... περισσότερα »

Sichere Shuntchirurgie – aus der Sicht des Nephrologen

Alexandros G. SfakianakisστοAnaesthesiologyΠριν από 40 δευτερόλεπτα
Sichere Shuntchirurgie – aus der Sicht des Nephrologen: Zusammenfassung HintergrundAufgrund des zunehmenden Alters und der Komorbiditäten der Dialysepatienten haben sich die Voraussetzungen für Dialysezugänge und für eine sichere Shuntchirurgie verändert. FragestellungWelchen Beitrag leistet der Nephrologe zur Sicherheit der Versorgung von Patienten mit chronischer Niereninsuffizienz mit Dialysezugängen? Material und MethodikErfahrungsbericht und Literaturübersicht von Nephrologen, eingebettet in ein interdisziplinäres Team für Gefäßzugänge. ErgebnisseEine wesentliche Ko... περισσότερα »

Patientensicherheit in der Shuntchirurgie

Alexandros G. SfakianakisστοAnaesthesiologyΠριν από 40 δευτερόλεπτα
Patientensicherheit in der Shuntchirurgie: Zusammenfassung HintergrundHämodialysepatienten, die operativ mit einem Gefäßzugang versorgt werden müssen, sind eine vulnerable Patientengruppe, die aufgrund von Multimorbidität, der intensiven und oft fragmentierten Behandlung und vieler Schnittstellen ein erhöhtes Risiko für vermeidbare unerwünschte Ereignisse tragen. FragestellungAktuelle Entwicklungen und Maßnahmen zur Förderung der Patientensicherheit mit Fokus auf die Shuntchirurgie. Material und MethodenAuswertung und Aufarbeitung aktueller Daten zur Patientensicherheit und I...περισσότερα »

Genetic screening for gynecological cancer: where are we heading?

Alexandros G. SfakianakisστοΟγκολογίαΠριν από 40 δευτερόλεπτα
Future Oncology Ahead of Print. from Cancer via ola Kala on Inoreader http://ift.tt/1OQRYlP via IFTTT

Single-Dose of Submucosal Injection of Dexamethasone Affects the Post Operative QOL

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 41 δευτερόλεπτα
Single-Dose of Submucosal Injection of Dexamethasone Affects the Post Operative Quality of Life After Third Molar Surgery: Abstract IntroductionThird molar surgery (TMS) became a routine, safe office procedure with generally predictable outcomes and relative low cost. It affects quality of life (QOL) of patients by causing considerable pain, swelling and trismus; by changing what people eat, their speech in the first few days after surgery. The purpose of the present study was to improve QOL of patient after lower TMS by injecting single dose 8 mg submucosal dexamethasone. Mat... περισσότερα »

Tracheotomietechniken

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 41 δευτερόλεπτα
Tracheotomietechniken: ZusammenfassungDurch die flächendeckende Etablierung moderner Verfahren hat sich die Tracheotomie zu einem Routineeingriff in der Intensivmedizin entwickelt. Durch die Tracheotomie können negative Effekte einer prolongierten translaryngealen Intubation auf die Larynx- und Trachealschleimhaut bis hin zur Trachealstenose vermindert werden. Weiterhin wird die Langzeitbeatmung bei kritisch kranken Patienten erleichtert. Es gibt allerdings keine eindeutige Evidenz über den optimalen Zeitpunkt der Tracheotomie bei Intensivpatienten. Für die sichere und erfolgreich...περισσότερα »

Mastoid Dimensions in Children and Young Adults: Consequences for the Geometry of Transcutaneous Bone-Conduction Implants.

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 41 δευτερόλεπτα
Mastoid Dimensions in Children and Young Adults: Consequences for the Geometry of Transcutaneous Bone-Conduction Implants.: Objectives: Bone-conduction implants (BCI) are available for adults and children who are aged 5 years or more. Because a transcutaneous bone-conduction implant introduced in 2013 does not completely fit into all adult mastoids, we investigated mastoid dimensions and the possibility of fitting the implant in children. Design: Computed tomography scans of 151 mastoids from 80 children and young adolescents from the age of 5 months to 20 years and 52 control masto...περισσότερα »

Audible Tinnitus

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 41 δευτερόλεπτα
Audible 2 Tinnitus Review: Tinnitus, also known as ringing of the ears, can be one of the most frustrating physical problems a person can deal with in their lives. With doctors having few answers as to what causes it and why it seems to come and go at times, patients with this condition can get frustrated to say the least. As with most other physical problems people face, there are those who claim to offer solutions to their problems, and tinnitus is no exception. One of the latest products to come along claiming to have the answers to combat tinnitus is the Audible 2, a type of he... περισσότερα »

Many faces of REM sleep behavior disorder

Alexandros G. SfakianakisστοΥπνική Άπνοια και Διαταραχές ΎπνουΠριν από 42 δευτερόλεπτα
Many faces of REM sleep behavior disorder: an editorial: Since the first description of rapid-eye movement sleep behavior disorder (RBD) as a REM parasomnia in 19861 the concept of RBD has been evolving. The initial concept of RBD being an idiopathic parasomnia began to change since the investigators who originally described this entity observed that 38% of their original cohort of 29 idiopathic RBD (iRBD) patients developed signs and symptoms of Parkinson's disease (PD) 10 years after the inital description.2 Since this publication the concept shifted dramatically from idiopathic t... περισσότερα »

The Journal of the Acoustical Society of America

Alexandros G. SfakianakisστοΑκοή και ΙσορροπίαΠριν από 47 δευτερόλεπτα
Airgun inter-pulse noise field during a seismic survey in an Arctic ultra shallow marine environment seismic Low-frequency sound level in the Southern Indian Ocean sound Coding pitch differences in voiceless fricatives: Whispered relative to normal speech Intonation Underdetermined reverberant acoustic source separation using weighted full-rank nonnegative tensor models K Effects of voice style, noise level, and acoustic feedback on objective and subjective voice evaluations room acoustic Enhancing cell kill in vitro from hyperthermia through pre-sensitizing with ultrasound-stimulated ... περισσότερα »

Prevalence and risk factors for reduced sound tolerance (hyperacusis) in children

Alexandros G. SfakianakisστοΑκοή και ΙσορροπίαΠριν από 47 δευτερόλεπτα
10.3109/14992027.2015.1092055<br>Amanda J. Hall from #Audiology via xlomafota13 on Inoreader http://ift.tt/1QbFHLP via IFTTT

Age and gender differences in children and adolescents’ attitudes toward noise

Alexandros G. SfakianakisστοΑκοή και ΙσορροπίαΠριν από 47 δευτερόλεπτα
10.3109/14992027.2015.1098784<br>Andrea D. Warner-Czyz from #Audiology via xlomafota13 on Inoreader http://ift.tt/1Txk9au via IFTTT

Audible 2 Tinnitus Review

Alexandros G. SfakianakisστοΑκοή και ΙσορροπίαΠριν από 47 δευτερόλεπτα
Tinnitus, also known as ringing of the ears, can be one of the most frustrating physical problems a person can deal with in their lives. With doctors having few answers as to what causes it and why it seems to come and go at times, patients with this condition can get frustrated to say the least. As with most other physical problems people face, there are those who claim to offer solutions to their problems, and tinnitus is no exception. One of the latest products to come along claiming to have the answers to combat tinnitus is the Audible 2, a type of hearing aid that is supposed... περισσότερα »

Prevalence and risk factors for reduced sound tolerance (hyperacusis) in children

Alexandros G. SfakianakisστοΑκοή και ΙσορροπίαΠριν από 47 δευτερόλεπτα
10.3109/14992027.2015.1092055<br>Amanda J. Hall from #Audiology via ola Kala on Inoreader http://ift.tt/1jL4fgn via IFTTT

Age and gender differences in children and adolescents’ attitudes toward noise

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 49 δευτερόλεπτα
Age and gender differences in children and adolescents’ attitudes toward noise Abstract *Objective*: Most school-aged children experience exposure to hazardous sound levels via high-risk noise activities (e.g. loud music/concerts, firearms). Little information exists regarding factors influencing pediatric engagement in these activities and use of hearing protection devices. This study explores effects of age, gender, and attitudes toward noise on participation in acoustic risk-taking behaviors and hearing conservation practices in children and adolescents. *Design*: Cross-secti... περισσότερα »

Prevalence and risk factors for reduced sound tolerance (hyperacusis) in children

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 49 δευτερόλεπτα
Prevalence and risk factors for reduced sound tolerance (hyperacusis) in children Abstract *Objective*: To estimate the prevalence of reduced sound tolerance (hyperacusis) in a UK population of 11-year-old children and examine the association of early life and auditory risk factors with report of hyperacusis. *Design*: A prospective UK population-based study. *Study sample*: A total of 7097 eleven-year-old children within the Avon longitudinal study of parents and children (ALSPAC) were asked about sound tolerance; hearing and middle-ear function was measured using audiometry, o... περισσότερα »

Effect of Triple Combination of Induction, Concurrent and Adjuvant Chemotherapy in High Risk Nasopharyngeal Carcinoma

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 50 δευτερόλεπτα
Effect of Triple Combination of Induction, Concurrent and Adjuvant Chemotherapy in High Risk Nasopharyngeal Carcinoma: *Condition*: Nasopharyngeal Carcinoma *Interventions*: Drug: Cisplatin 1; Drug: Cisplatin 2; Drug: Docetaxel; Drug: Xeloda; Radiation: Intensity-modulated radiotherapy *Sponsors*: Sun Yat-sen University; Affiliated Tumor Hospital of Guangzhou Medical University; The First Affiliated Hospital of Guangzhou Medical University; The First Affiliated Hospital of Guangdong Pharmaceutical University ArmsAssigned InterventionsExperimental: IC plus CC ... περισσότερα »

Exercise Protocol of Multisensory Rehabilitation in Treatment of the Complaints Vestibular: Clinical Trial Random

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 50 δευτερόλεπτα
Exercise Protocol of Multisensory Rehabilitation in Treatment of the Complaints Vestibular: Clinical Trial Random: *Condition*: Vestibular Diseases *Interventions*: Other: Intervention Group (IG); Other: Control Group (CG) *Sponsor*: Viviane de Souza Pinho Costa Vertigo, dizziness and imbalance are the main symptoms of vestibular dysfunction. They can lead to physical consequences, such as the reduction of postural control and falls, psychological and / or psychiatric consequences such as anxiety and depression, panic and cognitive changes, especially in the elderly. It ... περισσότερα »

Bullet in the Parapharyngeal Space

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 52 δευτερόλεπτα
Ballistic Reconstruction of a Migrating Bullet in the Parapharyngeal Space: A 21-year-old male suffering from severe throat pain after being hit by a bullet in Syria claimed that he was shot through his eye and that the bullet subsequently descended behind his throat. Even though the first medical report stated that this course is implausible, meticulous workup provided evidence that the bullet might have entered the parapharyngeal space in a more cranial position than the one it was found eight months later. Our case highlights that bullets are able to move within the body, renderi... περισσότερα »

Head and neck adenoid cystic carcinoma

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 57 δευτερόλεπτα
: A prospective multicenter REFCOR study of 95 cases via European Annals of Otorhinolaryngology, Head and Neck Diseases *Source:*European Annals of Otorhinolaryngology, Head and Neck Diseases Author(s): M. Meyers, B. Granger, P. Herman, F. Janot, R. Garrel, N. Fakhry, G. Poissonnet, B. Baujat ObjectivesTo describe the clinical, histological and therapeutic characteristics of a prospective multicenter series of 95 head and neck adenoid cystic carcinoma patients, and to determine any prognostic factors for disease-free survival.Patients and methodsNinety-five patients with adenoid cysti...περισσότερα »

Nocardia nova sphenoid sinusitis and infratemporal fossa abscess

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 58 δευτερόλεπτα
Nocardia nova sphenoid sinusitis and infratemporal fossa abscess via European Annals of Otorhinolaryngology, Head and Neck Diseases Figures and tables 1. [image: CT scan confirming left ethmoid and sphenoid sinusitis.] 2. [image: a. Sinus CT scan showing an abscess in the left pterygoid muscles; b. CT scan, ...] *Source:*European Annals of Otorhinolaryngology, Head and Neck Diseases Author(s): A. Giordano, M. Cohen-Salmon, B. Joly, C. Maffiolo IntroductionNocardia sinusitis is exceptional, as a Medline search revealed only one published case. The authors report a case of ... περισσότερα »

Nasal obstruction in children

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 58 δευτερόλεπτα
Nasal obstruction in children via European Annals of Otorhinolaryngology, Head and Neck Diseases *Source:*European Annals of Otorhinolaryngology, Head and Neck Diseases Author(s): N. Leboulanger Figures and tables 1. [image: Facial CT, bone window, axial slice: infant; right choanal atresia.] 2. [image: Right nasal cavity, endoscopic view; nasolacrimal cyst under right inferior ...] 3. [image: Facial CT, bone window, frontal slice: infant; large congenital right nasal ...] 4. [image: T1-weighted facial MRI, sagittal slice. Neonate of a few days of age. Large... περισσότερα »

Child cochlear implant bearers

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 58 δευτερόλεπτα
Self- and parental assessment of quality of life in via European Annals of Otorhinolaryngology, Head and Neck Diseases *Source:*European Annals of Otorhinolaryngology, Head and Neck Diseases Author(s): T. Razafimahefa-Raoelina, A. Farinetti, R. Nicollas, J.-M. Triglia, S. Roman, L. Anderson ObjectivesThe aim of this study was to assess quality of life in children fitted with cochlear implants, using combined self- and parental assessment.Materials and methodsThirty-two children, aged 6 to 17 years, with prelingual hearing loss and receiving cochlear implants at a mean age of 22 month...περισσότερα »

Outer ear swelling: Childhood auricular rhabdomyosarcoma

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 1 ώρα
Unusual via European Annals of Otorhinolaryngology, Head and Neck Diseases Publication date: Available online 20 October 2015 *Source:*European Annals of Otorhinolaryngology, Head and Neck Diseases Author(s): M. Chirat, L. Dainese, S. Fasola, V. Couloigner, F. Denoyelle, E.-N. Garabedian, N. Leboulanger Figures and tables 1. [image: Patient #1, primary lesion at biopsy.] 2. [image: a: patient #1, malignant proliferation comprising islands separated by thin ...] 3. [image: Patient #2, primary lesion.] IntroductionRhabdomyosarcoma (RMS) is the most frequent soft-tissue ... περισσότερα »

Fibula free flap in the treatment of mandibular osteoradionecrosis

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 1 ώρα
Fibula free flap in the treatment of mandibular osteoradionecrosis via European Annals of Otorhinolaryngology, Head and Neck Diseases Publication date: Available online 26 October 2015 *Source:*European Annals of Otorhinolaryngology, Head and Neck Diseases Author(s): S. Baron, D. Salvan, L. Cloutier, I. Gharzouli, N. Le Clerc Figures and tables 1. Table 1 2. Table 2 3. [image: Trismus assessment: a: Preoperative; b: Postoperative.] 4. Table 3 5. [image: Dental rehabilitation. Implantation and vestibuloplasty.] IntroductionMandibular osteoradionecrosis (mOR... περισσότερα »

Substernal goiter

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 1 ώρα
: Experience with 50 cases via European Annals of Otorhinolaryngology, Head and Neck Diseases Publication date: Available online 29 October 2015 *Source:*European Annals of Otorhinolaryngology, Head and Neck Diseases Author(s): M. Benbakh, M. Abou-elfadl, S. Rouadi, R.-L. Abada, M. Roubal, M. Mahtar Figures and tables 1. [image: Frontal clinical examination showing telangiectasias.] 2. [image: Lateral clinical examination: large substernal goiter.] IntroductionGoiter is localized or generalized thyroid hypertrophy. It is usually cervical, but may show intra-thoracic developm... περισσότερα »

ORL residency,Tracheotomy in children,Retropharyngeal neurofibroma,The superior semicircular canal,Neonatal hearing-loss screening,Speech perception, production and intelligibility in French-speaking children with profound hearing loss and early cochlear implantation after congenital cytomegalovirus infection

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 1 ώρα
A rare case study of a retropharyngeal neurofibroma and a brief literature review Publication date: Available online 4 December 2015 *Source:*European Annals of Otorhinolaryngology, Head and Neck Diseases Author(s): I. Atallah, J. Gervasoni, E. Gay, C.A. Righini Introduction Space occupying lesions in the retropharyngeal space are rare. Case report Here, we present a rare case of a retropharyngeal neurofibroma treated surgically through an open cervical approach without any complication. Discussion Neurofibromas are benign, slowly growing neoplasms that could be associated or not wit...περισσότερα »

A radiologic and anatomic study of the superior semicircular canal

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 1 ώρα
A radiologic and anatomic study of the superior semicircular canal via Otorhinolaryngology Publication date: Available online 3 December 2015 *Source:*European Annals of Otorhinolaryngology, Head and Neck Diseases Author(s): N. Klopp-Dutote, C. Kolski, A. Biet, V. Strunski, C. Page [image: Methodology: A) Determination of SSC dehiscence grade; B) Measurement of SSC ...] ObjectivesThe present study sought to determine whether there is a correlation between the prevalence of superior semicircular canal (SSC) dehiscence (SSCD) on temporal CT and population age. The secondary objective was ...περισσότερα »

Ectopic lingual thyroid

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 1 ώρα
Ectopic lingual thyroid via Otorhinolaryngology *Source:*European Annals of Otorhinolaryngology, Head and Neck Diseases Author(s): J. Gotlib, A. Ianessi, J. Santini, O. Dassonville [image: MRI, axial T1-weighted sequence demonstrating ectopic lingual thyroid.] [image: Intra-operative view of the lingual thyroid.]

Ear Mite Removal : Controlling Risk Factors for Cancer Development

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 1 ώρα
Ear Mite Removal in the Santa Catalina Island Fox (Urocyon littoralis catalinae): Controlling Risk Factors for Cancer Development: by Megan E. Moriarty, T. Winston Vickers, Deana L. Clifford, David K. Garcelon, Patricia M. Gaffney, Kenneth W. Lee, Julie L. King, Calvin L. Duncan, Walter M. Boyce Ear mites (*Otodectes cynotis*) and ear canal tumors are highly prevalent among federally endangered Island foxes (*Urocyon littoralis catalinae*) living on Santa Catalina Island off the coast of Southern California. Since studies began in the 1990s, nearly all foxes examined were found to ... περισσότερα »

The Prevalence of Airway Problems in Children with Down's Syndrome

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 1 ώρα
The Prevalence of Airway Problems in Children with Down's Syndrome: Airway disorders are common in children with Down's Syndrome. We report the findings on airway endoscopy in a birth cohort of children from a well-defined geographical area, in order to estimate true population prevalence of airway problems in children with Down's Syndrome.

Factors Related to Persisting Perforations after Ventilation Tube Insertion

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 1 ώρα
Factors Related to Persisting Perforations after Ventilation Tube Insertion: Over a million ventilation tubes are placed annually in the United States, making this one of the most commonly performed procedures in the field of medicine. Certain factors increase the risk of persistent tympanic membrane perforation following the extrusion of short term ventilation tubes. Persistent perforations may fail to heal on their own necessitating surgical closure to avoid conductive hearing loss. It is important to detect factors that may predict children who are at increased risk for persisten... περισσότερα »

The Validation of an Algorithm for the Management of Paediatric Cervical Lymphadenopathy

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 1 ώρα
The Validation of an Algorithm for the Management of Paediatric Cervical Lymphadenopathy: Neck lumps are common in children, with cervical lymphadenopathy being the most frequent cause [1,2]. Infective or inflammatory lymphadenitis is attributed as a potential cause of lymphadenopathy through all stages of childhood [3]. The majority of enlarged nodes are reactive and malignancy is rare. When presented with a child with a neck lump the clinician must exclude malignancy but should not over investigate or perform unnecessary procedures.

Involvement of astrocyte and oligodendrocyte gene sets in migraine

Alexandros G. SfakianakisστοΝευρολογία κ' ΝευροχειρουργικήΠριν από 1 ώρα
Involvement of astrocyte and oligodendrocyte gene sets in migraine: Background Migraine is a common episodic brain disorder characterized by recurrent attacks of severe unilateral headache and additional neurological symptoms. Two main migraine types can be distinguished based on the presence of aura symptoms that can accompany the headache: migraine with aura and migraine without aura. Multiple genetic and environmental factors confer disease susceptibility. Recent genome-wide association studies (GWAS) indicate that migraine susceptibility genes are involved in various pathways, i...περισσότερα »

Comparison of complications in patients receiving different types of intracranial pressure monitoring: a retrospective study in a single center in Switzerland

Alexandros G. SfakianakisστοΝευρολογία κ' ΝευροχειρουργικήΠριν από 1 ώρα
Publication date: Available online 7 December 2015 *Source:*World Neurosurgery Author(s): Julien Dimitriou, Marc Levivier, Marinella Gugliotta from Neurology via xlomafota13 on Inoreader http://ift.tt/1NSJ7CY via IFTTT

Single-Dose of Submucosal Injection of Dexamethasone Affects the Post Operative Quality of Life After Third Molar Surgery

Abstract Introduction Third molar surgery (TMS) became a routine, safe office procedure with generally predictable outcomes and relative low cost. It affects quality of life (QOL) of patients by causing considerable pain, swelling and trismus; by changing what people eat, their speech in the first few days after surgery. The purpose of the present study was to improve QOL of patient after lower TMS by injecting single dose 8 mg submucosal dexamethasone. Materials and Methods Forty healthy adult subjects of either gender underwent surgical removal of the lower impacted third molar ... περισσότερα »

MicroRNA-31 upregulation predicts increased risk of progression of oral potentially malignant disorder

Oral squamous cell carcinoma (OSCC), which accounts for two-thirds of head and neck squamous cell carcinoma (HNSCC), is one of the most prevalent cancers worldwide. OSCC typically develops from oral potentially malignant disorder (OPMD) and is attributed to smoking, betel nut or tobacco chewing, and HPV infection. The most common type of OPMD is oral leukoplakia that histopathologically presents as hyperkeratosis, epithelial hyperplasia, or dysplasia. High-grade epithelial dysplasia has a malignant transformation rate as high as 26.8% [1]. from #ΓναθοΧειρουργική via xlomafota13 on...περισσότερα »

Genetic screening for gynecological cancer: where are we heading?

Alexandros G. SfakianakisστοΟγκολογίαΠριν από 1 ώρα
Future Oncology Ahead of Print. from Cancer via ola Kala on Inoreader http://ift.tt/1OQRYlP via IFTTT

Bone Marker-Directed Dosing of Zoledronic Acid for the Prevention of Skeletal Complications in Patients With Multiple Myeloma: Results of the Z-MARK Study

Alexandros G. SfakianakisστοΟγκολογίαΠριν από 1 ώρα
Background: Zoledronic acid (ZOL) given every 3 to 4 weeks can reduce skeletal-related events (SREs) in patients with bone lesions from multiple myeloma. This study evaluated efficacy and safety of less-frequent ZOL dosing based on bone turnover markers in patients with 1 to 2 years of prior bisphosphonate therapy. Methods: Patients received ZOL (4 mg) every 4 or 12 weeks based on urinary N-telopeptide of type 1 collagen (uNTX) levels (every 4 weeks if uNTX ≥50 nmol/mmol creatinine, every 12 weeks if uNTX &lt;50). Results: Of 121 patients enrolled (mean age, 63.8 years; median follow... περισσότερα »

A Phase I Study of the Safety, Pharmacokinetics, and Pharmacodynamics of Combination Therapy with Refametinib plus Sorafenib in Patients with Advanced Cancer

Alexandros G. SfakianakisστοΟγκολογίαΠριν από 1 ώρα
Purpose: To assess the safety and tolerability of the small-molecule allosteric MEK inhibitor refametinib combined with sorafenib, in patients with advanced solid malignancies. Methods: This phase I dose-escalation study included an expansion phase at the maximum tolerated dose (MTD). Patients received refametinib/sorafenib twice daily (BID) for 28 days, from a dose of refametinib 5 mg plus sorafenib 200 mg to a dose of refametinib 50 mg plus sorafenib 400 mg. Plasma levels of refametinib, refametinib metabolite M17, and sorafenib were measured for pharmacokinetic assessments. Tum...περισσότερα »

Age and gender differences in children and adolescents’ attitudes toward noise

Alexandros G. SfakianakisστοΑκοή και ΙσορροπίαΠριν από 1 ώρα
10.3109/14992027.2015.1098784<br>Andrea D. Warner-Czyz from #Audiology via ola Kala on Inoreader http://ift.tt/1jL4eZZ via IFTTT

Prevalence and risk factors for reduced sound tolerance (hyperacusis) in children

Alexandros G. SfakianakisστοΑκοή και ΙσορροπίαΠριν από 1 ώρα
10.3109/14992027.2015.1092055<br>Amanda J. Hall from #Audiology via ola Kala on Inoreader http://ift.tt/1QbFHLP via IFTTT

Age and gender differences in children and adolescents’ attitudes toward noise

Alexandros G. SfakianakisστοΑκοή και ΙσορροπίαΠριν από 1 ώρα
10.3109/14992027.2015.1098784<br>Andrea D. Warner-Czyz from #Audiology via ola Kala on Inoreader http://ift.tt/1Txk9au via IFTTT

Inflammatory myofibroblastic tumor-like stromal proliferation within gastric inverted hyperplastic polyp

Alexandros G. SfakianakisστοCell and Tissue Research by Alexandros G. SfakianakisΠριν από 1 ώρα
from Anatomy Pathology via xlomafota13 on Inoreader http://ift.tt/1IBvm9F via IFTTT

Multinodular and vacuolating neuronal tumor affecting amygdala and hippocampus: A quasi-tumor?

Alexandros G. SfakianakisστοCell and Tissue Research by Alexandros G. SfakianakisΠριν από 1 ώρα
Multinodular and vacuolating neuronal tumors (MVNT) have been referred to as distinctive neuronal tumors whose characteristic features include multiple nodules localized in the subcortical white matter. MVNT are composed of vacuolating dysplastic neurons reactive to HuC/HuD. A significant overexpression of alpha-internexin (INA) limited to the stroma of nodules was reported in one tumor. Since genetic analyses have failed to demonstrate any consistent alterations, the nosological position as well as the nature of MVNT, namely, neoplastic or dysplastic, remains unclear. We herein ...περισσότερα »

Long-term patterns of relapse and survival following definitive intensity-modulated radiotherapy for non-endemic nasopharyngeal carcinoma

Intensity-modulated radiotherapy has developed into the standard definitive treatment for nasopharyngeal carcinoma over the past 15years, in both the United States and in Asia, where Epstein-Barr virus-related non-keratinizing carcinomas of the nasopharynx are endemic [1,2]. Three randomized trials have compared IMRT to conventional radiotherapy in the treatment of NPC [3–5]. Although local control rates with IMRT have improved with the advent and now widespread adoption of IMRT, distant recurrence remains a persistent problem. from #ΓναθοΧειρουργική via xlomafota13 on Inoreader h... περισσότερα »

Factors affecting survival following self-inflicted head and neck gunshot wounds: a single-centre retrospective review

Self-inflicted head and neck gunshot wounds are a common modality of suicide in the USA. This study reviewed all self-inflicted head and neck gunshot wound patients with complete records (n=157) treated at a tertiary centre between 2002 and 2012 inclusive. The associations between mortality and patient/clinical variables were evaluated with the χ2 test or Fisher's exact test for statistical difference testing. Outcomes recorded were death (n=92, 59%), discharge to long-term care/rehabilitation (n=58, 37%), and discharge home (n=7, 4%). from #ΓναθοΧειρουργική via xlomafota13 on Ino...περισσότερα »