Selective tissue ablation using laser radiation at 355 nm in lead extraction
Selective tissue ablation using laser radiation at 355 nm in lead extraction by a hybrid catheter; a preliminary report: Background Current lead extraction (LE) devices can harm the blood vessel endothelium, increasing the risk of perforation. Objective Proof of concept for using a solid-state pulsed laser at 355 nm with a hybrid catheter in LE. Methods A hybrid catheter was used comprising optical fibers for the delivery of 355 nm laser pulses at 30 Hz and 6 J/cm2 combined with a blunt mechanical blade. Specific parameters were chosen to enable selectivity in ablation, thereby redu... περισσότερα »
Treatment of facial photodamage and rhytides using a novel 1,565 nm non-ablative fractional erbium-doped fiber laser
Treatment of facial photodamage and rhytides using a novel 1,565 nm non-ablative fractional erbium-doped fiber laser: Background and Objective Non-ablative fractional lasers (NAFL) generate microscopic non-contiguous columns of thermal injury in the dermis, resulting in collagen remodeling. This manuscript details our experience with a novel 1,565 nm scanned, erbium-doped fiber NAFL for the treatment of facial photodamage. Study Design/Materials and Methods A prospective, open-label clinical trial was conducted at two clinical sites in the United States on 16 female subjects with a m... περισσότερα »
Laser treatment of infantile hemangioma
Laser treatment of infantile hemangioma: A systematic review: Background and Objective To systematically review studies of laser treatment of infantile hemangioma (IH). Study Design/Methods and Materials We searched multiple databases including MEDLINE® and EMBASE from 1982 to June 2015. Two investigators independently screened studies against predetermined criteria and extracted key data. Investigators independently assessed study risk of bias and the strength of the evidence of the body of literature. Results We identified 29 studies addressing lasers: 4 randomized controlled trial...περισσότερα »
Violet 405 nm light against β-lactam-resistant Escherichia coli
Violet 405 nm light: A novel therapeutic agent against β-lactam-resistant Escherichia coli: Background and Objective Approximately 1.7 million patients are affected by hospital-acquired infections every year in the United States. The increasing prevalence of multidrug-resistant bacteria associated with these infections prompts the investigation of alternative sterilization and antibacterial therapies. One method currently under investigation is the antibacterial properties of visible light. This study examines the effect of a visible light therapy (VLT) on β-lactam-resistant *Esche... περισσότερα »
Fast Helical Tomotherapy in a head and neck cancer
Fast Helical Tomotherapy in a head and neck cancer planning study: is time priceless?: The last few years, in radiotherapy there has been a growing focus on speed of treatment delivery (largely driven by economical and commercial interests). This study investigates the influence of treatment tim... Abstract Background The last few years, in radiotherapy there has been a growing focus on speed of treatment delivery (largely driven by economical and commercial interests). This study investigates the influence of treatment time on plan quality for helical tomotherapy (HT), using... περισσότερα »
Intramuscular Transplantation Improves Engraftment Rates for Esophageal Patient-Derived Tumor Xenografts
Intramuscular Transplantation Improves Engraftment Rates for Esophageal Patient-Derived Tumor Xenografts: Abstract BackgroundRecently, there has been an increase in the availability of targeted molecular therapies for cancer treatment. The application of these approaches to esophageal cancer, however, has been hampered by the relative lack of appropriate models for preclinical testing. Patient-derived tumor xenograft (PDTX) models are gaining popularity for studying many cancers. Unfortunately, it has proven difficult to generate xenografts from esophageal cancer using these model...περισσότερα »
Inflammatory CXCL12-CXCR4/CXCR7 axis mediates G-protein signaling pathway to influence the invasion and migration of nasopharyngeal carcinoma cells
Inflammatory CXCL12-CXCR4/CXCR7 axis mediates G-protein signaling pathway to influence the invasion and migration of nasopharyngeal carcinoma cells: AbstractThis study explored whether the migration, invasion, and apoptosis of nasopharyngeal carcinoma (NPC) cells were affected by the CXCR4/CXCR7-CXCL12 axis and if this mechanism was related to G-protein signaling pathway. A total of 72 NPC patients admitted in our hospital between April 2013 and February 2015 were incorporated in this study. Immunohistochemistry was performed to compare the expression levels of CXCR4, CXCR7, and CX... περισσότερα »
Household inhalants exposure and nasopharyngeal carcinoma risk
Household inhalants exposure and nasopharyngeal carcinoma risk: a large-scale case-control study in Guangdong, China: Abstract BackgroundEpidemiological studies show that cigarette smoking increase the risk of nasopharyngeal carcinoma (NPC), however, whether other common, potentially adverse household inhalants increase NPC risk remains uncertain. MethodsWe conducted a large case-control study to explore the effects of household inhalants, such as incense, mosquito coil, cooking fumes, and wood combustion, on NPC risk. We recruited 1,845 cases and 2,275 controls from Guangdong ...περισσότερα »
An economic evaluation of an augmented cognitive behavioural intervention vs. computerized cognitive training for post-stroke depressive symptoms
Abstract Background Stroke survivors encounter emotional problems in the chronic phase after stroke. Post-stroke depressive symptoms have major impact on health-related quality of life (HRQol) and lead to increased hospitalization and therefore substantial healthcare costs. We present a cost-effectiveness and cost-utility evaluation of a cognitive behavioural therapy augmented with occupational and movement therapy to support patients with a stroke with depressive symptoms in goal-setting and goal attainment (augmented CBT) in comparison with a computerized cognitive training progr...περισσότερα »
Increases in absenteeism among health care workers in Hong Kong during influenza epidemics, 2004–2009
Acute respiratory infections (ARI) are a major cause of sickness absenteeism among health care workers (HCWs) and contribute significantly to overall productivity loss particularly during influenza epidemics. ... from Infection via ola Kala on Inoreader http://ift.tt/1R7vFdI via IFTTT
Vaccinate-assess-move method of mass canine rabies vaccination utilising mobile technology data collection in Ranchi, India
Over 20 000 people die from rabies each year in India. At least 95 % of people contract rabies from an infected dog. Annual vaccination of over 70 % of the dog population has eliminated both canine and human r... from Infection via ola Kala on Inoreader http://ift.tt/1NVhfJm via IFTTT
An evidence synthesis approach to estimating the incidence of symptomatic pertussis infection in the Netherlands, 2005–2011
Despite high vaccination coverage, infection with Bordetella pertussis is a current public health concern in the Netherlands and other European Union member states. Because surveillance data are subject to extens... from Infection via ola Kala on Inoreader http://ift.tt/1R7vDme via IFTTT
Cinco casos de urticaria multiforme y revisión de la literatura
Publication date: January–February 2016 *Source:*Actas Dermo-Sifiliográficas, Volume 107, Issue 1 Author(s): L. Sempau, E. Martín-Sáez, C. Gutiérrez-Rodríguez, M.C. Gutiérrez-Ortega La urticaria multiforme es un cuadro cutáneo, propio de lactantes y niños pequeños, caracterizado por la aparición de grandes placas anulares urticariformes de centro violáceo frecuentemente asociado a un proceso febril. Tiene un curso benigno y autolimitado, pero el llamativo aspecto de las lesiones puede ser alarmante y generar gran ansiedad en los padres.Presentamos 5 casos de urticaria multiforme vis...περισσότερα »
Histochemical Evaluation of the Vessel Wall Destruction and Selectivity After Treatment with Intense Pulsed Light in Capillary Malformations
Publication date: Available online 29 December 2015 *Source:*Actas Dermo-Sifiliográficas Author(s): E. Grillo, A. Rita Travassos, P. Boixeda, A. Cuevas, B. Pérez, J. Paoli, P. Jaén BackgroundAmong the different approaches for improving the effectiveness in the treatment of Capillary Malformations type Port Wine Stain (CM type PWS) are the intense pulsed light sources. There are few clinical studies prove useful in the treatment of CM. Furthermore, no studies have been published yet demonstrating the histological effects of IPL in CM.ObjectivesTo assess the histological effects of pu... περισσότερα »
Simplifying Blepharoplasty
[image: image]Learning Objectives: After reading this article, the participant should be able to: 1. Identify pertinent eyelid and periorbital anatomical structures when evaluating a patient for blepharoplasty. 2. Adequately evaluate a patient by performing a focused history-taking and medical examination tailored for the aging eyelid patient. 3. Identify the aging changes that have occurred, and determine the particular changes that will be addressed surgically. 4. Determine a safe and effective surgical plan. Summary: Blepharoplasty remains one of the most common aesthetic procedu... περισσότερα »
Discussion: The Impact of Radiation Therapy, Lymph Node Dissection, and Hormonal Therapy on Outcomes of Tissue Expander–Implant Exchange in Prosthetic Breast Reconstruction
[image: image]No abstract available from #Aesthetics via alexandrossfakianakis on Inoreader http://ift.tt/1UfWtrE via IFTTT
Meningeal carcinomatosis underdiagnosis and overestimation
Meningeal carcinomatosis underdiagnosis and overestimation: incidence in a large consecutive and unselected population of breast cancer patients: Abstract BackgroundThe incidence of meningeal carcinomatosis appears to be higher than in the past due to advances in neuro-imaging diagnostic techniques and improvements in cancer survival. Among solid tumors, breast cancer is the cancer most commonly associated with meningeal carcinomatosis, with an incidence rate of between 0.8 and 16 %. Aim of this study has been i) to evaluate the incidence of meningeal carcinomatosis in a continuous...περισσότερα »
Oral sorafenib and topotecan in refractory or recurrent pediatric solid malignancies
Pediatric phase I trial of oral sorafenib and topotecan in refractory or recurrent pediatric solid malignancies: Abstract Targeted kinase inhibitors and camptothecins have shown preclinical and clinical activity in several cancers. This trial evaluated the maximum tolerated dose (MTD) and dose-limiting toxicities of sorafenib and topotecan administered orally in pediatric patients with relapsed solid tumors. Sorafenib was administered twice daily and topotecan once daily on days 1–5 and 8–12 of each 28-day course. The study utilized a standard 3 + 3 dose escalation design. Three do... περισσότερα »
Parity and thyroid cancer risk
Parity and thyroid cancer risk: a meta-analysis of epidemiological studies: Abstract Although observational studies have assessed the relationship between parity and thyroid cancer risk, the findings are inconsistent. To quantitatively assess the association, we conducted a systematic review and meta-analysis. PubMed and Embase were searched up to January 2015. Prospective or case–control studies that evaluated the association between parity and thyroid cancer risk were included. We used the fixed-effects model to pool risk estimates. After literature search, 10 prospective studies... περισσότερα »
Carotid compression : Bilateral Eagle syndrome
Paradoxical ischemia in bilateral Eagle syndrome: a case of false-localization from c via Clinical Neurology and Neurosurgery [image: S03038467.gif] [image: (A) Cervical CT angiogram with 3-D reconstruction, right anterior oblique view. ...] Publication date: February 2016 *Source:*Clinical Neurology and Neurosurgery, Volume 141 Author(s): Michael C. Dewan, Peter J. Morone, Scott L. Zuckerman, Nishit Mummareddy, Mayshan Ghiassi, Mahan Ghiassi
Subcortical interhemispheric connectivity and cortical hemispheric dominance in brain tumor
Correlating subcortical interhemispheric connectivity and cortical hemispheric dominance in brain tumor patients: A repetitive navigated transcranial magnetic stimulation study via Clinical Neurology and Neurosurgery [image: S03038467.gif] Publication date: February 2016 *Source:*Clinical Neurology and Neurosurgery, Volume 141 Author(s): Nico Sollmann, Sebastian Ille, Lorena Tussis, Stefanie Maurer, Theresa Hauck, Chiara Negwer, Jan S. Bauer, Florian Ringel, Bernhard Meyer, Sandro M. Krieg ObjectiveThe present study aims to investigate the relationship between transcallosal interhemi... περισσότερα »
Keratinocyte growth factor-2 inhibits bacterial infection with Pseudomonas aeruginosa pneumonia in a mouse model
sfakianakistherapeuticsστοTherapeutics Infections Emergencies MEDICINE BY ALEXANDROS G.SFAKIANAKIS,ANAPAFSEOS 5 AGIOS NIKOLAOS,CRETE 72100,GREECE,TEL :00302841026182 & 00306932607174Πριν από 11 δευτερόλεπτα
Publication date: January 2016 Source:Journal of Infection and Chemotherapy, Volume 22, Issue 1 Author(s): Nana Feng, Qin Wang, Jian Zhou, Jing Li, Xiaoxing Wen, Shujing Chen, Zhenhua Zhu, Chunxue Bai, Yuanlin Song, Huayin Li To determine protective effects of concurrent administration of Keratinocyte growth factor-2 (KGF-2) with Pseudomonas aeruginosa (P. aeruginosa) inoculation on the induced […]
Pleural tuberculosis in a patient with untreated type 1 Gaucher disease
sfakianakistherapeuticsστοTherapeutics Infections Emergencies MEDICINE BY ALEXANDROS G.SFAKIANAKIS,ANAPAFSEOS 5 AGIOS NIKOLAOS,CRETE 72100,GREECE,TEL :00302841026182 & 00306932607174Πριν από 11 δευτερόλεπτα
Publication date: January 2016 Source:Journal of Infection and Chemotherapy, Volume 22, Issue 1 Author(s): Ozgecan Dulgar, Ahmet Emre Eskazan, Ezel Ersen, Ahu Senem Demiroz, Akif Turna, Buge Oz, Nukhet Tuzuner Gaucher disease (GD) is an autosomal recessive glycolipid storage disorder, due to deficiency of the lysosomal enzyme glucocerebrosidase, leading to accumulation of the substrate glucocerebroside […]
A case of testicular infarction from the complications of Klebsiella oxytoca induced acute epididymitis
sfakianakistherapeuticsστοTherapeutics Infections Emergencies MEDICINE BY ALEXANDROS G.SFAKIANAKIS,ANAPAFSEOS 5 AGIOS NIKOLAOS,CRETE 72100,GREECE,TEL :00302841026182 & 00306932607174Πριν από 11 δευτερόλεπτα
Publication date: Available online 28 November 2015 Source:Journal of Infection and Chemotherapy Author(s): Wonae Lee, Heeyoon Park, Gilho Lee Herein, we reported a case of testicular infarction in a patient with Klebsiella oxytoca induced acute epididymitis. Acute left epididymitis progressed into testicular infarction requiring orchiectomy in spite of antibiotics treatment. Ordinary urine cultures did not […]
High-level aminoglycoside resistance in Enterococcus faecalis and Enterococcus faecium causing invasive infection: Twelve-year surveillance in the Minami Ibaraki Area
sfakianakistherapeuticsστοTherapeutics Infections Emergencies MEDICINE BY ALEXANDROS G.SFAKIANAKIS,ANAPAFSEOS 5 AGIOS NIKOLAOS,CRETE 72100,GREECE,TEL :00302841026182 & 00306932607174Πριν από 11 δευτερόλεπτα
Publication date: January 2016 Source:Journal of Infection and Chemotherapy, Volume 22, Issue 1 Author(s): Hanako Osuka, Jun Nakajima, Tsuyoshi Oishi, Yasunori Funayama, Tsugio Ebihara, Hiroichi Ishikawa, Kazuto Saito, Hiroshi Koganemaru, Shigemi Hitomi We examined prevalence of high-level aminoglycoside resistance (HLAR) in Enterococcus faecalis and Enterococcus faecium causing invasive infection in the Minami Ibaraki Area. Ten […]
Thoracoscopic examination of empyema in a patient with sparganosis mansoni
sfakianakistherapeuticsστοTherapeutics Infections Emergencies MEDICINE BY ALEXANDROS G.SFAKIANAKIS,ANAPAFSEOS 5 AGIOS NIKOLAOS,CRETE 72100,GREECE,TEL :00302841026182 & 00306932607174Πριν από 11 δευτερόλεπτα
Publication date: Available online 19 November 2015 Source:Journal of Infection and Chemotherapy Author(s): Keita Takeda, Junko Suzuki, Hideaki Nagai, Kaoru Watanabe, Akira Yokoyama, Takahiro Ando, Jun Suzuki, Nobuharu Ohshima, Kimihiko Masuda, Atsuhisa Tamura, Shinobu Akagawa, Masashi Kitani, Akira Hebisawa, Hirotoshi Matsui, Nobuyuki Kobayashi, Haruhiko Maruyama, Ken Ohta A 27-year-old man was admitted to our hospital […]
Successful treatment of methicillin-resistant Staphylococcus aureus osteomyelitis with combination therapy using linezolid and rifampicin under therapeutic drug monitoring
sfakianakistherapeuticsστοTherapeutics Infections Emergencies MEDICINE BY ALEXANDROS G.SFAKIANAKIS,ANAPAFSEOS 5 AGIOS NIKOLAOS,CRETE 72100,GREECE,TEL :00302841026182 & 00306932607174Πριν από 11 δευτερόλεπτα
Publication date: Available online 28 December 2015 Source:Journal of Infection and Chemotherapy Author(s): Nobuyuki Ashizawa, Yasuhiro Tsuji, Koyomi Kawago, Yoshitsugu Higashi, Masato Tashiro, Makiko Nogami, Ryuichi Gejo, Munetoshi Narukawa, Tomoatsu Kimura, Yoshihiro Yamamoto Linezolid is an effective antibiotic against most gram-positive bacteria including drug-resistant strains such as methicillin-resistant Staphylococcus aureus. Although linezolid therapy is known […]
Simplifying Blepharoplasty
sfakianakismedicsστοORL ALLERGY AESTHETICS ANATOMY Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 11 δευτερόλεπτα
Learning Objectives: After reading this article, the participant should be able to: 1. Identify pertinent eyelid and periorbital anatomical structures when evaluating a patient for blepharoplasty. 2. Adequately evaluate a patient by performing a focused history-taking and medical examination tailored for the aging eyelid patient. 3. Identify the aging changes that have occurred, and determine […]
Discussion: The Impact of Radiation Therapy, Lymph Node Dissection, and Hormonal Therapy on Outcomes of Tissue Expander–Implant Exchange in Prosthetic Breast Reconstruction
sfakianakismedicsστοORL ALLERGY AESTHETICS ANATOMY Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 11 δευτερόλεπτα
No abstract available from Aesthetic via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1UfWtrE via IFTTT
ASPS/PSF Sponsored Symposia and Workshops
sfakianakismedicsστοORL ALLERGY AESTHETICS ANATOMY Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 11 δευτερόλεπτα
No abstract available from Aesthetic via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1mQ0vwk via IFTTT
The Impact of Travel Distance on Breast Reconstruction in the United States
sfakianakismedicsστοORL ALLERGY AESTHETICS ANATOMY Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 11 δευτερόλεπτα
Background: Inadequate access to breast reconstruction was a motivating factor underlying passage of the Women’s Health and Cancer Rights Act. It remains unclear whether all patients interested in breast reconstruction undergo this procedure. The aim of this study was to determine whether geographic disparities are present that limit the rate and method of postmastectomy reconstruction. […]
Reply: The Short-Scar Periareolar Inferior Pedicle Reduction Technique in Severe Mammary Hypertrophy
sfakianakismedicsστοORL ALLERGY AESTHETICS ANATOMY Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 11 δευτερόλεπτα
No abstract available from Aesthetic via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1UfWtrx via IFTTT
Clinical Applications of the Transverse Musculocutaneous Gracilis Flap for Secondary Breast Reconstruction after Simple Mastectomy
sfakianakismedicsστοORL ALLERGY AESTHETICS ANATOMY Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 11 δευτερόλεπτα
Background: In secondary autologous breast reconstruction, the current standard is a flap derived from the lower abdomen or the back. If these donor sites are not available because of lack of tissue, prior operations, or simply the patient’s desire to avoid these donor sites, the authors use the transverse musculocutaneous gracilis flap if feasible. Methods: […]
Optimizing Successful Outcomes in Complex Spine Reconstruction Using Local Muscle Flaps
sfakianakismedicsστοORL ALLERGY AESTHETICS ANATOMY Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 11 δευτερόλεπτα
Background: Postoperative wound complications in patients undergoing complex spinal surgery can have devastating sequelae, including hardware exposure, meningitis, and unplanned reoperation. The literature shows that wound complication rates in this patient population approach 19 percent and, in very high-risk patients (i.e., prior spinal surgery, existing spinal wound infection, cerebrospinal fluid leak, malignancy, or history of […]
Superficial Inferior Epigastric Artery: Learning Curve versus Reality
sfakianakismedicsστοORL ALLERGY AESTHETICS ANATOMY Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 11 δευτερόλεπτα
Background: Breast reconstruction with the superficial inferior epigastric artery (SIEA) free flap continues to gain popularity among reconstructive surgeons. The low risk for abdominal wall morbidity must be weighed against the higher concern for thrombotic events. The aim of this study was to review the authors’ recent experience with the SIEA flap and investigate whether […]
How to Put Your Best Self Forward in Plastic Surgery Residency Interviews
sfakianakismedicsστοORL ALLERGY AESTHETICS ANATOMY Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 11 δευτερόλεπτα
No abstract available from Aesthetic via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1mQ0s3E via IFTTT
The Low DIEP Flap: An Enhancement to the Abdominal Donor Site
sfakianakismedicsστοORL ALLERGY AESTHETICS ANATOMY Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 11 δευτερόλεπτα
Background: A serious drawback of the deep inferior epigastric perforator (DIEP) flap is an abdominal scar that is too high. Because the umbilicus should be incorporated into the flap territory, lowering the scar is very difficult. This report describes a new DIEP flap design where the flap is placed in the lowermost part of the […]
ASPS/PSF Sponsored Symposia and Workshops
No abstract available from #Aesthetics via alexandrossfakianakis on Inoreader http://ift.tt/1mQ0vwk via IFTTT
The Impact of Travel Distance on Breast Reconstruction in the United States
[image: image]Background: Inadequate access to breast reconstruction was a motivating factor underlying passage of the Women's Health and Cancer Rights Act. It remains unclear whether all patients interested in breast reconstruction undergo this procedure. The aim of this study was to determine whether geographic disparities are present that limit the rate and method of postmastectomy reconstruction. Methods: Travel distance in miles between the patient's residence and the hospital reporting the case was used as a quantitative measure of geographic disparities. The American College ...περισσότερα »
Reply: The Short-Scar Periareolar Inferior Pedicle Reduction Technique in Severe Mammary Hypertrophy
No abstract available from #Aesthetics via alexandrossfakianakis on Inoreader http://ift.tt/1UfWtrx via IFTTT
Clinical Applications of the Transverse Musculocutaneous Gracilis Flap for Secondary Breast Reconstruction after Simple Mastectomy
[image: image]Background: In secondary autologous breast reconstruction, the current standard is a flap derived from the lower abdomen or the back. If these donor sites are not available because of lack of tissue, prior operations, or simply the patient's desire to avoid these donor sites, the authors use the transverse musculocutaneous gracilis flap if feasible. Methods: The authors retrospectively evaluated only patients where secondary autologous breast reconstruction was performed with a transverse musculocutaneous gracilis flap because of the prior mentioned reasons. Indication...περισσότερα »
Optimizing Successful Outcomes in Complex Spine Reconstruction Using Local Muscle Flaps
[image: image]Background: Postoperative wound complications in patients undergoing complex spinal surgery can have devastating sequelae, including hardware exposure, meningitis, and unplanned reoperation. The literature shows that wound complication rates in this patient population approach 19 percent and, in very high-risk patients (i.e., prior spinal surgery, existing spinal wound infection, cerebrospinal fluid leak, malignancy, or history of radiation therapy), as high as 40 percent and with reoperation rates as high as 12 percent. The authors investigated whether prophylactic cl... περισσότερα »
Superficial Inferior Epigastric Artery: Learning Curve versus Reality
[image: image]Background: Breast reconstruction with the superficial inferior epigastric artery (SIEA) free flap continues to gain popularity among reconstructive surgeons. The low risk for abdominal wall morbidity must be weighed against the higher concern for thrombotic events. The aim of this study was to review the authors' recent experience with the SIEA flap and investigate whether their previously published incidences of vessel thrombosis and flap loss were related to their own "learning curve" or whether these adverse events are attributable to inherent qualities of the SIEA... περισσότερα »
How to Put Your Best Self Forward in Plastic Surgery Residency Interviews
No abstract available from #Aesthetics via alexandrossfakianakis on Inoreader http://ift.tt/1mQ0s3E via IFTTT
The Low DIEP Flap: An Enhancement to the Abdominal Donor Site
[image: image]Background: A serious drawback of the deep inferior epigastric perforator (DIEP) flap is an abdominal scar that is too high. Because the umbilicus should be incorporated into the flap territory, lowering the scar is very difficult. This report describes a new DIEP flap design where the flap is placed in the lowermost part of the abdomen, well below the umbilicus, similar to a mini-abdominoplasty. Methods: The low DIEP flap was used only for cases with moderately sized breasts and reliable perforators way below the umbilicus. The flap's lower border was on the pubic rim... περισσότερα »
In-Flap Anastomosis as Back-Up Option for Anterolateral Thigh Flaps Lacking Suitable Perforators
[image: image]No abstract available from #Aesthetics via alexandrossfakianakis on Inoreader http://ift.tt/1mQ0rNe via IFTTT
Carbon Dioxide versus Saline Tissue Expanders: Does It Matter?
[image: image]Background: Implant-based breast reconstruction is the most common reconstructive technique in the United States. Despite its popularity, saline-based tissue expansion still has its limitations, including lengthy expansion times, large uncomfortable bolus dosing, and frequent percutaneous injections/expansion visits. Ideally, a novel technology would eliminate frequent, percutaneous saline injections and allow patients to perform expansion at home, reducing the disruptive experience of current tissue expansion. Methods: Within the past 6 years, the AeroForm tissue expa... περισσότερα »
Extracorporeal Septoplasty: Assessing Functional Outcomes Using the Validated Nasal Obstruction Symptom Evaluation Score over a 3-Year Period
[image: image]Background: It is well recognized that the standard septoplasty approach, in patients with severe septal deformities, may be less than adequate to address all portions of the deviated septum. The extracorporeal septoplasty technique is an alternative to the other common approaches in these more severe cases. In this study, the authors investigate functional outcomes of the standard approach. The authors use the validated Nasal Obstruction Symptom Evaluation score, before and after surgery, to quantify symptom improvement and confirm the validity and usefulness of this ... περισσότερα »
Sounds and Drink Tastes/Textures
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 19 δευτερόλεπτα
Cross-Modal Associations between Sounds and Drink Tastes/Textures: A Study with Spontaneous Production of Sound-Symbolic Words: Many languages have a word class whose speech sounds are linked to sensory experiences. Several recent studies have demonstrated cross-modal associations (or correspondences) between sounds and gustatory sensations by asking participants to match predefined sound-symbolic words (e.g., «maluma/takete») with the […]
Closure Techniques and Scar Appearance
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 19 δευτερόλεπτα
Closure Techniques and Scar Appearance: Condition: Wound Closure Techniques Interventions: Procedure: Running polypropylene closure; Procedure: Tissue Adhesive (Derma-Bond); Procedure: Subcuticular polyglactin-910 combined with tissue adhesive Sponsor: Northwestern University The goal of this study is to assess whether wound closure with skin adhesive or running stitches combined with skin adhesive will be superior to standard wound […]
Recommended Articles
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 19 δευτερόλεπτα
Publication date: December 2015 Source:Journal of Acupuncture and Meridian Studies, Volume 8, Issue 6 from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1YS5tED via IFTTT
Racial/Ethnic Differences in Trajectories of Cognitive Function in Older Adults: Role of Education, Smoking, and Physical Activity
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 19 δευτερόλεπτα
Objective: The objective of this study is to (a) examine racial/ethnic differences in trajectories of cognitive function and (b) evaluate the role of education and health behaviors (physical activity [PA] and smoking) as mediators of racial/ethnic differences in the rate of decline in cognitive function in older adults. Method: Data for this study came from […]
Combined PET/CT-perfusion in patients with head and neck cancers might predict failure after radio-chemotherapy: a proof of concept study
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 19 δευτερόλεπτα
Abstract Background [18F]FDG-PET/CT imaging is broadly used in head and neck cancer (HNSCC) patients. CT perfusion (CTP) is known to provide information about angiogenesis and blood-flow characteristics in tumors. The aim of this study was to evaluate the potential relationship of FDG-parameters and CTP-parameters in HNSCC preand post-therapy and the potential prognostic value of a […]
A chest radiograph scoring system in patients with severe acute respiratory infection: a validation study
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 19 δευτερόλεπτα
Abstract Background The term severe acute respiratory infection (SARI) encompasses a heterogeneous group of respiratory illnesses. Grading the severity of SARI is currently reliant on indirect disease severity measures such as respiratory and heart rate, and the need for oxygen or intensive care. With the lungs being the primary organ system involved in SARI, chest […]
Identification of a novel mechanism of action of fingolimod (FTY720) on human effector T cell function through TCF-1 upregulation
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 19 δευτερόλεπτα
Background: Fingolimod (FTY720), the first oral treatment for multiple sclerosis (MS), blocks immune cell trafficking and prevents disease relapses by downregulation of sphingosine-1-phosphate receptor. We determined the effect of FTY720 on human T cell activation and effector function. Methods: T cells from MS patients and healthy controls were isolated to measure gene expression profiles in […]
Acid-sensing ion channel 1a contributes to the effect of extracellular acidosis on NLRP1 inflammasome activation in cortical neurons
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 19 δευτερόλεπτα
Background: Acid-sensing ion channels (ASICs) are cation channels which were activated by extracellular acidosis and involved in various physiological and pathological processes in the nervous system. Inflammasome is a key component of the innate immune response in host against harmful and irritable stimuli. As the first discovered molecular platform, NLRP1 (nucleotide-binding oligomerization domain (NOD)-like receptor […]
Ligand engagement of Toll-like receptors regulates their expression in cortical microglia and astrocytes
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 19 δευτερόλεπτα
Background: Toll-like receptor (TLR) activation on microglia and astrocytes are key elements in neuroinflammation which accompanies a number of neurological disorders. While TLR activation on glia is well-established to up-regulate pro-inflammatory mediator expression, much less is known about how ligand engagement of one TLR may affect expression of other TLRs on microglia and astrocytes. Methods: […]
Antagonist of the neurokinin-1 receptor curbs neuroinflammation in ex vivo and in vitro models of Lyme neuroborreliosis
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 19 δευτερόλεπτα
Background: Lyme neuroborreliosis (LNB) can affect both the peripheral (PNS) and the central nervous systems (CNS); it is caused by the spirochete Borrelia burgdorferi. The neuropeptide substance P (SP) is an important mediator of both neuroinflammation and blood-brain barrier dysfunction, through its NK 1 receptor. Increased levels of SP have been shown to correlate with […]
Cerebral vasospasm (CV) and associated secondary brain injury
Microparticle derived proteins as potential biomarkers for cerebral vasospasm post subarachnoid hemorrhage. A preliminary study via Clinical Neurology and Neurosurgery [image: S03038467.gif] Publication date: February 2016 *Source:*Clinical Neurology and Neurosurgery, Volume 141 Author(s): Magdalena M. Przybycien-Szymanska, Yuchen Yang, William W. Ashley ObjectiveCerebral vasospasm (CV) and associated secondary brain injury are major contributors to death and disability after aneurysmal subarachnoid hemorrhage (aSAH). Microparticles (MP) are small vesicular micro-molecules released by... περισσότερα »
Proceedings of the Aristotelian Society
Proceedings of the Aristotelian Society, published by Oxford University Press, last updated on 2015-12-29, available at http://ift.tt/22xVMzW from #ORL-AlexandrosSfakianakis via simeraentaxei on Inoreader http://ift.tt/22xVMzW via IFTTT
Racial/Ethnic Differences in Trajectories of Cognitive Function in Older Adults: Role of Education, Smoking, and Physical Activity
Objective: The objective of this study is to (a) examine racial/ethnic differences in trajectories of cognitive function and (b) evaluate the role of education and health behaviors (physical activity [PA] and smoking) as mediators of racial/ethnic differences in the rate of decline in cognitive function in older adults. Method: Data for this study came from… Continue reading Racial/Ethnic Differences in Trajectories of Cognitive Function in Older Adults: Role of Education, Smoking, and Physical Activity
Arg354 in the catalytic centre of bovine liver catalase is protected from methylglyoxal-mediated glycation
In addition to controlled post-translational modifications proteins can be modified with highly reactive compounds. Usually this leads to a compromised functionality of the protein. Methylglyoxal is one of the… from #ORL-AlexandrosSfakianakis via simeraentaxei on Inoreader http://ift.tt/1Vp4NXh via IFTTT
Immunogenicity and clinical effectiveness of the trivalent inactivated influenza vaccine in immunocompromised children undergoing treatment for cancer
Abstract Influenza is associated with significant morbidity and mortality in children receiving therapy for cancer, yet recommendation for, and uptake of the seasonal vaccine remains poor. One hundred children undergoing treatment for cancer were vaccinated with the trivalent inactivated influenza vaccine according to national guidelines in 2010 and 2011. Influenza-specific hemagglutinin inhibition antibody titers were… Continue reading Immunogenicity and clinical effectiveness of the trivalent inactivated influenza vaccine in immunocompromised children undergoing treatment for cancer
Retrospective analysis of systemic chemotherapy and total parenteral nutrition for the treatment of malignant small bowel obstruction
Abstract Malignant small bowel obstruction (MSBO) that does not resolve with conservative measures frequently leaves few treatment options other than palliative care. This single-institution retrospective study assesses the outcomes of a more aggressive approach—concurrent systemic chemotherapy and total parenteral nutrition (TPN)—in the treatment of MSBO. The MD Anderson pharmacy database was queried to identify patients… Continue reading Retrospective analysis of systemic chemotherapy and total parenteral nutrition for the treatment of malignant small bowel obstruction
Simplifying Blepharoplasty
Learning Objectives: After reading this article, the participant should be able to: 1. Identify pertinent eyelid and periorbital anatomical structures when evaluating a patient for blepharoplasty. 2. Adequately evaluate a patient by performing a focused history-taking and medical examination tailored for the aging eyelid patient. 3. Identify the aging changes that have occurred, and determine… Continue reading Simplifying Blepharoplasty
Parity and thyroid cancer risk: a meta-analysis of epidemiological studies
Abstract Although observational studies have assessed the relationship between parity and thyroid cancer risk, the findings are inconsistent. To quantitatively assess the association, we conducted a systematic review and meta-analysis. PubMed and Embase were searched up to January 2015. Prospective or case–control studies that evaluated the association between parity and thyroid cancer risk were included.… Continue reading Parity and thyroid cancer risk: a meta-analysis of epidemiological studies
Discussion: The Impact of Radiation Therapy, Lymph Node Dissection, and Hormonal Therapy on Outcomes of Tissue Expander–Implant Exchange in Prosthetic Breast Reconstruction
No abstract available from #ORL-AlexandrosSfakianakis via ola Kala on Inoreader http://ift.tt/1UfWtrE via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1OjZffa via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1OwWKYW via IFTTT
KRAS mutation in lung metastases from colorectal cancer: prognostic implications
Abstract KRAS mutant colorectal cancer (CRC) patients develop lung and brain metastases more frequently than KRAS wild-type (WT) counterpart. We retrospectively investigated the prognostic role of KRAS, BRAF, and PIK3CA (exon 20) mutations and loss of phosphatase and tensin homolog (PTEN) in surgically resected lung metastases. Lung specimens from 75 metastatic CRC (mCRC) patients treated… Continue reading KRAS mutation in lung metastases from colorectal cancer: prognostic implications
Targeting the PI3K signaling pathway in KRAS mutant colon cancer
Abstract Metastatic colorectal cancer (CRC) patients with v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog (KRAS) mutations are resistant to monoclonal antibody that targets the epidermal growth factor receptor such as cetuximab. BKM120 targets phosphatidylinositide-3-kinase (PIK3CA), but it is unknown whether BKM120 can reverse cetuximab resistance in KRAS mutant CRC. Human CRC cell lines with KRAS… Continue reading Targeting the PI3K signaling pathway in KRAS mutant colon cancer
Gamma Knife Radiosurgery in the management of single and multiple brain metastases
Gamma Knife Radiosurgery in the management of single and multiple brain metastases via Clinical Neurology and Neurosurgery [image: S03038467.gif] Publication date: February 2016 *Source:*Clinical Neurology and Neurosurgery, Volume 141 Author(s): D. Greto, S. Scoccianti, A. Compagnucci, C. Arilli, M. Casati, G. Francolini, S. Cecchini, M. Loi, I. Desideri, L. Bordi, P. Bono, P. Bonomo, I. Meattini, B. Detti, L. Livi ObjectivesTo evaluate the efficacy and safety of Gamma Knife Radiosurgery (GKRS) in the treatment of single and multiple brain metastases.Patients and methodsFrom October ... περισσότερα »
Identification of Corynebacterium Species and Other Medically Relevant Coryneform-Like Bacteria
Practical Utility and Accuracy of Matrix-Assisted Laser Desorption Ionization-Time of Flight Mass Spectrometry for Identification of Corynebacterium Species and Other Medically Relevant Coryneform-Like Bacteria: *Background:* *Corynebacterium* species and gram-positive coryneform-like bacteria (coryneforms) are increasingly reported causes of opportunistic infections in immunocompromised patients. Biochemical identification methods for these bacteria are often inaccurate. We evaluated matrix-assisted laser desorption ionization–time of flight mass spectrometry (MALDI-TOF MS) for r... περισσότερα »
Patient-reported health-related quality of life after a displaced intra-articular calcaneal fracture: a systematic review
Background: A displaced intra-articular calcaneal fracture (DIACF) is known for having a negative influence on the daily activities of patients. A health-related quality of life (HRQoL) outcome instrument is used to quantify the impact of DIACF. It seems that these studies used restrictive inclusion criteria and observe specific patient groups; consequently, an increased risk of bias that results in incorrect estimation of the impact. Therefore, we will systematically review the current literature.Materials and methodsA systematic search was performed in PubMed, Embase and Cochrane... περισσότερα »
Extranodal Natural Killer/T-Cell Lymphoma in Children and Adolescents
Extranodal Natural Killer/T-Cell Lymphoma in Children and Adolescents: A Report of 17 Cases in China: *Objectives:* To investigate the clinicopathologic features of extranodal natural killer/T-cell lymphoma (ENKTL) not preceded by another Epstein-Barr virus (EBV)–related disorder in children and adolescents. *Methods:* A series of 17 cases of ENKTL not preceded by another EBV-related disorder in children and adolescents in one institution from China was retrospectively analyzed. *Results:* The patients had a median age of 13 years (range, 2-17 years), and the male to female ratio ...περισσότερα »
Rapid QuickFISH Testing for Detection of Coagulase-Negative Staphylococci
The Impact of Implementation of Rapid QuickFISH Testing for Detection of Coagulase-Negative Staphylococci at a Community-Based Hospital: *Objectives:* A study was conducted to evaluate the impact of implementing the *Staphylococcus Quick*FISH assay (AdvanDx, Woburn, MA), which rapidly detects and differentiates *Staphylococcus aureus* from coagulase-negative staphylococci (CoNS), together with an antimicrobial stewardship program on treating patients suspected of having sepsis. *Methods:* Two patient groups showing CoNS in positive blood cultures were evaluated by either convention... περισσότερα »
Nasal mask versus nasal prongs for delivering nasal continuous positive airway pressure in preterm infants with respiratory distress: A randomized controlled trial
Nasal mask versus nasal prongs for delivering nasal continuous positive airway pressure in preterm infants with respiratory distress: A randomized controlled trial: Abstract ObjectiveTo compare the effectiveness of nasal continuous positive airway pressure delivered by Nasal mask *vs* Nasal prongs with respect to continuous positive airway pressure failure. Study designRandomized, controlled, open label, trial. SettingTertiary care level III neonatal unit. Participants118 preterm infants-gestational age (27-34 weeks) requiring nasal continuous positive airway pressure as... περισσότερα »
Myositis Ossificans of the Temporalis Muscle
Myositis Ossificans of the Temporalis Muscle: AbstractTraumatic myositis ossificans (TMO) is a rare ossifying disease that occurs in the muscle or soft tissues. A case of TMO isolated in the temporalis muscle is reported. In the case described, calcification in the temporalis muscle was confirmed after computed tomography. Surgery, physiotherapy, and histopathological analysis were performed. One year after treatment, further ossification was present but without interference in function. The most accepted treatment for TMO in the maxillofacial region is excision followed by physiot... περισσότερα »
Myoepithelial carcinoma of salivary glands
Clinicopathological characteristics and cell cycle proteins as potential prognostic factors in myoepithelial carcinoma of salivary glands: AbstractMyoepithelial carcinoma (MCA) is a rare malignancy of salivary glands that was included in the WHO Classification of Head and Neck Tumors in 1991. MCA has shown a broad spectrum of clinical outcomes, but attempts to identify prognostic markers for this malignancy have not resulted in significant progress. Conventional histopathological characteristics such as tumour grade, nuclear atypia, mitotic index and cell proliferation have failed ...περισσότερα »
Combination of Vancomycin and {beta}-Lactam Therapy for MRSA
Combination of Vancomycin and {beta}-Lactam Therapy for Methicillin-Resistant Staphylococcus aureus Bacteremia: A Pilot Multicenter Randomized Controlled Trial: *Background.* In vitro laboratory and animal studies demonstrate a synergistic role for the combination of vancomycin and antistaphylococcal β-lactams for methicillin-resistant *Staphylococcus aureus* (MRSA) bacteremia. Prospective clinical data are lacking. *Methods.* In this open-label, multicenter, clinical trial, adults with MRSA bacteremia received vancomycin 1.5 g intravenously twice daily and were randomly assigned ... περισσότερα »
Sex Dimorphism Profile of Alzheimer’s Disease
Sex Dimorphism Profile of Alzheimer’s Disease-Type Pathologies in an APP/PS1 Mouse Model: AbstractAlzheimer’s disease (AD) is the most common form of dementia among the elderly, characterized by parenchymal and vascular beta-amyloid (Aβ) burden, tau pathology, neuroinflammation, and loss of neurons and synapses. There is a clear sex difference in the prevalence of AD. However, sex differences in AD-type pathologies have not been systematically documented. Applying 12-month-old female and male APP/PS1 mice as a model, we investigated the sex dimorphism in these major pathological in... περισσότερα »
Skeletal muscle after cadmium exposure
Structural and functional changes in the zebrafish ( Danio rerio ) skeletal muscle after cadmium exposure: AbstractThis report describes the alterations induced by an environmentally realistic concentration of cadmium in skeletal muscle fibre organization, composition, and function in the teleost zebrafish. Results demonstrate that the ion induces a significant quantitative and qualitative deterioration, disrupting sarcomeric pattern and altering glycoprotein composition. These events, together with a mitochondrial damage, result in a significant reduction in swimming performance. ... περισσότερα »
Genetic Evolution of Nevus of Ota Reveals Clonal Heterogeneity Acquiring BAP1 and TP53 Mutations
Genetic Evolution of Nevus of Ota Reveals Clonal Heterogeneity Acquiring BAP1 and TP53 Mutations: Summary Melanoma presents molecular alterations based on its anatomical location and exposure to environmental factors. Due to its intrinsic genetic heterogeneity, a simple snapshot of a tumor's genetic alterations does not reflect the tumor clonal complexity or specific gene-gene cooperation. Here, we studied the genetic alterations and clonal evolution of a unique patient with a Nevus of Ota that developed into a recurring uveal-like dermal melanoma. The Nevus of Ota and ulterior les... περισσότερα »
Reticulate acropigmentation of Kitamura
Behavior of melanocytes and keratinocytes in reticulate acropigmentation of Kitamura: Abstract Reticulate acropigmentation of Kitamura (RAK, OMIM 615537) is a rare genetic pigmentary disorder that usually shows an autosomal dominant pattern of inheritance with high penetrance. The disorder was first described by Kitamura and Akamatsu in 1943, and then reported worldwide in 1953 (Kitamura et al., 1953). RAK patients typically present within the first or second decade of life with angulated and slightly depressed reticulate hyperpigmentation on the dorsum of the extremities without ... περισσότερα »
Greater occipital nerve blocks as migraine therapy: A discussion of two recent randomized, double-blinded, placebo-controlled clinical trials
Greater occipital nerve blocks as migraine therapy: A discussion of two recent randomized, double-blinded, placebo-controlled clinical trials Greater occipital nerve blocks as migraine therapy: A discussion of two recent randomized, double-blinded, placebocontrolled clinical trials Dear Editor: Although greater occipital nerve block (GONB) had been advocated for decades as migraine therapy, the procedure had not been scientifically studied. Recently two randomized double-blinded placebo-controlled trials (RCTs) for prophylactic treatment of migraine were published (1,2). The RCTs came t...περισσότερα »
Sounds and Drink Tastes/Textures
Cross-Modal Associations between Sounds and Drink Tastes/Textures: A Study with Spontaneous Production of Sound-Symbolic Words: Many languages have a word class whose speech sounds are linked to sensory experiences. Several recent studies have demonstrated cross-modal associations (or correspondences) between sounds and gustatory sensations by asking participants to match predefined sound-symbolic words (e.g., "maluma/takete") with the taste/texture of foods. Here, we further explore cross-modal associations using the spontaneous production of words and semantic ratings of sensatio... περισσότερα »
Closure Techniques and Scar Appearance
Closure Techniques and Scar Appearance: *Condition*: Wound Closure Techniques *Interventions*: Procedure: Running polypropylene closure; Procedure: Tissue Adhesive (Derma-Bond); Procedure: Subcuticular polyglactin-910 combined with tissue adhesive *Sponsor*: Northwestern University The goal of this study is to assess whether wound closure with skin adhesive or running stitches combined with skin adhesive will be superior to standard wound sutures. This is a split-wound study that will compare two methods of skin closure within one standard closure technique, thereby pr... περισσότερα »
OnabotulinumtoxinA for the Treatment of New Daily Persistent Headache
OnabotulinumtoxinA for the Treatment of New Daily Persistent Headache: an Open Label Study: *Condition*: New Daily Persistent Headache *Intervention*: Drug: OnabotulinumtoxinA *Sponsors*: St. Luke's-Roosevelt Hospital Center; Allergan The purpose of this study is to evaluate the effect of BOTOX® (OnabotulinumtoxinA) on the number of headache days in patients with New Daily Persistent Headache (NDPH). NDPH is a benign form of chronic daily headache that comes in two forms: one that resolves on its own after months to years, or one that is difficult to treat and does not res... περισσότερα »
Functional Dimensions of Macintosh Laryngoscope Blade
Evaluation of Functional Dimensions of Macintosh Laryngoscope Blade During Direct Laryngoscopy in Patients With Normal Mouth Opening: *Condition*: Submucous Fibrosis *Intervention*: Other: Direct Laryngoscopy *Sponsor*: Sir Ganga Ram Hospital Direct laryngoscopy and intubation is an essential initial aspect of airway access during general anesthesia. To perform the procedure effectively, it requires adequate mouth opening, head and neck movement, and a normal temporo-mandibular joint mobility. Any issue with the above three results in a compromised upper airway at the outse... περισσότερα »
Docetaxel Polymeric Micelle (PM) in Recurrent or Metastatic HNSCC
Study to Evaluate the Efficacy and Safety of Docetaxel Polymeric Micelle (PM) in Recurrent or Metastatic HNSCC: *Condition*: Head and Neck Squamous Cell Carcinoma *Intervention*: Drug: Docetaxel-PM *Sponsor*: Samyang Biopharmaceuticals Corporation ArmsAssigned InterventionsExperimental: Docetaxel-PM Docetaxel-PM 75mg/m2 IV infusion Drug: Docetaxel-PM Docetaxel PM 75mg/m2 IV infusion Other Name: Nanoxel M
Adjuvant Cisplatin and Radiation With Pembrolizumab in Resected Head and Neck Squamous Cell Carcinoma
Phase II Trial of Adjuvant Cisplatin and Radiation With Pembrolizumab in Resected Head and Neck Squamous Cell Carcinoma: *Condition*: Head and Neck Cancer *Interventions*: Drug: Pembrolizumab; Procedure: Surgery; Radiation: Radiation Therapy; Drug: Cisplatin *Sponsors*: Trisha Wise-Draper; Merck Sharp & Dohme Corp. ArmsAssigned InterventionsExperimental: Pembrolizumab Pembrolizumab in combination with standard of care surgery followed by radiation therapy with or without cisplatin Drug: Pembrolizumab Pembrolizumab administered one week prior to surgery and then every ... περισσότερα »
Collodion membrane who had an obstructed external auditory canal
“Collodion Baby”: A unique challenge for newborn hearing screening: We present an infant with collodion membrane who had an obstructed external auditory canal, causing the infant to fail her newborn hearing screen (otoacoustic emissions) bilaterally. An auditory brainstem response (ABR) test was deferred due to the reported increased risk of infections in these babies. Meticulous but gentle debridement of the membranes on the external auditory canal, using a combination of otic drops (ofloxacin), emollients (baby oil/mineral oil), and suctioning, permitted the infant to ultimately p... περισσότερα »
The effect of high flow nasal cannula oxygen therapy on middle ear pressure
The effect of high flow nasal cannula oxygen therapy on middle ear pressure: To investigate the effect of high flow nasal cannula oxygen therapy (HFOT) on middle ear pressure. *Abstract*Objectives To investigate the effect of high flow nasal cannula oxygen therapy (HFOT) on middle ear pressure. Materials/Methods Ten patients (eight males and two females) with oxygen desaturations requiring HFOT were recruited with 19 ears available for our study. The study group was aged 29-90 years (mean 65.3 ± 16.5). All patients underwent a review of medical history, questioned about subjective... περισσότερα »
Venous Vascular Malformation of the Floor of Mouth Masquerading as a Dermoid Tumor
Venous Vascular Malformation of the Floor of Mouth Masquerading as a Dermoid Tumor: Venous vascular malformations (VVMs) are described as abnormal post-capillary lesions which exhibit low flow. These are typically malleable and may grow with endocrine fluctuations. A VVM that mimics the classic appearance of dermoid tumor on imaging has never been reported. We encountered a 43-year-old woman with intermittent dysphagia relating to a firm submandibular mass. Physical exam and cross-sectional imaging revealed features consistent with variant dermoid cyst. However, catheter angiography...περισσότερα »
Treatment of Meniere’s disease with Intratympanic Dexamethazone plus High Dosage of Betahistine
Treatment of Meniere’s disease with Intratympanic Dexamethazone plus High Dosage of Betahistine: The aim of the present study was to assess if the combined therapy of intratympanic dexamethasone (ITD) and high dosage of betahistine (HDBH) is able to provide increased vertigo control compared to ITD alone in patients suffering from definite unilateral Meniere’s disease (MD). *Abstract**Purpose* The aim of the present study was to assess if the combined therapy of intratympanic dexamethasone (ITD) and high dosage of betahistine (HDBH) is able to provide increased vertigo control co... περισσότερα »
Detection of Connexion 26 GENE (GJB2) Mutations in Cases of Congenital Non Syndromic Deafness
Detection of Connexion 26 GENE (GJB2) Mutations in Cases of Congenital Non Syndromic Deafness: AbstractHearing loss is most common form of genetic hearing disorder. Non-syndromic sensory neural autosomal recessive deafness (NSRD) is the most common form of genetic hearing loss. Mutations in GJB2 gene, which encodes the connexin 26 protein, are major cause of NSRD. The aim of this study is directed towards the mutations caused along the connexin 26 gene using blood samples from nonsyndromic deaf children. The study was conducted on 36 congenitally hearing impaired children who visit... περισσότερα »
The influence of multilevel upper airway surgery on CPAP tolerance in non-responders to obstructive sleep apnea surgery
The influence of multilevel upper airway surgery on CPAP tolerance in non-responders to obstructive sleep apnea surgery: AbstractThe aim of this study was to evaluate the influence of multilevel upper airway surgery on subsequent continuous positive airway pressure (CPAP) use and tolerance in patients with moderate to severe obstructive sleep apnea (OSA). The study cohort enrolled 67 consecutive patients, who underwent septoplasty plus modified uvulopharyngopalatoplasty (mUPPP) with or without modified tongue base suspension (mTBS) due to CPAP intolerance, and who had residual OSA ...περισσότερα »
Infiltration with lidocaine and adrenaline instead of normal saline does not improve the septoplasty procedure
Infiltration with lidocaine and adrenaline instead of normal saline does not improve the septoplasty procedure: AbstractThe aim of this study was to determine whether infiltration of local anesthetics with adrenaline improved septoplasty procedure when compared to normal saline. Eight-two patients undergoing septoplasty were randomized into two groups. In group 1, septal mucoperichondrium was infiltrated with lidocaine with adrenaline, and normal saline was used in group 2. Presence of intra-operative septal mucosal injuries, the amount of bleeding, arterial blood pressure, operati... περισσότερα »
Evaluating the referral preferences and consultation requests of primary care physicians with otolaryngology – head and neck surgery
Evaluating the referral preferences and consultation requests of primary care physicians with otolaryngology – head and neck surgery: Abstract BackgroundNo literature exists which examines referral preferences to, or the consultation process with, Otolaryngology. In a recent Canadian Medical Association nation-wide survey of General Practitioners and Family Physicians, Otolaryngology was listed as the second-most problematic specialty for referrals. The purpose of this study was to learn about and improve upon the referral process between primary care physicians (PCPs) and Otolary... περισσότερα »
Remote ischemic preconditioning in the prevention of ischemic brain damage
Remote ischemic preconditioning in the prevention of ischemic brain damage during intracranial aneurysm treatment (RIPAT): study protocol for a randomized controlled trial: Background: The treatment of intracranial aneurysms may be associated with cerebral ischemia. We hypothesize that pre-interventional remote ischemic preconditioning (RIPC) reduces ischemic cerebral tissue damage in patients undergoing elective intracranial aneurysm treatment.Methods/DesignThis study is a single-center, prospective, randomized, double-blind explorative trial. Patients with an unruptured intracrania...περισσότερα »
Detection of bacteria in middle ear effusions
Detection of bacteria in middle ear effusions based on the presence of allergy: does allergy augment bacterial infection in the middle ear?: Abstract BackgroundBacterial infection, Eustachian tube dysfunction, allergies, and immunologic factors are major causes of otitis media with effusion (OME). However, the exact pathogenesis of OME is still unclear. This study evaluated whether allergy influences bacterial growth in middle ear effusions. MaterialsFifty-four samples were obtained from OME patients 3–10 years of age who underwent ventilation tube insertion and were divided in... περισσότερα »
Cinco casos de urticaria multiforme y revisión de la literatura
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 47 δευτερόλεπτα
Publication date: January–February 2016 Source:Actas Dermo-Sifiliográficas, Volume 107, Issue 1 Author(s): L. Sempau, E. Martín-Sáez, C. Gutiérrez-Rodríguez, M.C. Gutiérrez-Ortega La urticaria multiforme es un cuadro cutáneo, propio de lactantes y niños pequeños, caracterizado por la aparición de grandes placas anulares urticariformes de centro violáceo frecuentemente asociado a un proceso febril. Tiene un curso benigno y […]
Retrospective analysis of systemic chemotherapy and total parenteral nutrition for the treatment of malignant small bowel obstruction
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 47 δευτερόλεπτα
Abstract Malignant small bowel obstruction (MSBO) that does not resolve with conservative measures frequently leaves few treatment options other than palliative care. This single-institution retrospective study assesses the outcomes of a more aggressive approach—concurrent systemic chemotherapy and total parenteral nutrition (TPN)—in the treatment of MSBO. The MD Anderson pharmacy database was queried to identify patients […]
Histochemical Evaluation of the Vessel Wall Destruction and Selectivity After Treatment with Intense Pulsed Light in Capillary Malformations
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 47 δευτερόλεπτα
Publication date: Available online 29 December 2015 Source:Actas Dermo-Sifiliográficas Author(s): E. Grillo, A. Rita Travassos, P. Boixeda, A. Cuevas, B. Pérez, J. Paoli, P. Jaén BackgroundAmong the different approaches for improving the effectiveness in the treatment of Capillary Malformations type Port Wine Stain (CM type PWS) are the intense pulsed light sources. There are few […]
KRAS mutation in lung metastases from colorectal cancer: prognostic implications
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 47 δευτερόλεπτα
Abstract KRAS mutant colorectal cancer (CRC) patients develop lung and brain metastases more frequently than KRAS wild-type (WT) counterpart. We retrospectively investigated the prognostic role of KRAS, BRAF, and PIK3CA (exon 20) mutations and loss of phosphatase and tensin homolog (PTEN) in surgically resected lung metastases. Lung specimens from 75 metastatic CRC (mCRC) patients treated […]
Lesiones lobuladas en los dedos de la mano
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 47 δευτερόλεπτα
Publication date: Available online 29 December 2015 Source:Actas Dermo-Sifiliográficas Author(s): M. Toro-Montecinos, A. Plana-Pla, L. Barboza-Guadagnini, C. Rodriguez-Caruncho from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1PwBrnv via IFTTT
Targeting the PI3K signaling pathway in KRAS mutant colon cancer
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 47 δευτερόλεπτα
Abstract Metastatic colorectal cancer (CRC) patients with v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog (KRAS) mutations are resistant to monoclonal antibody that targets the epidermal growth factor receptor such as cetuximab. BKM120 targets phosphatidylinositide-3-kinase (PIK3CA), but it is unknown whether BKM120 can reverse cetuximab resistance in KRAS mutant CRC. Human CRC cell lines with KRAS […]
Foreword to Special Topic Section on the Interface of Positive Psychology with Rehabilitation Research and Practice
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 47 δευτερόλεπτα
from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1NUYiGL via IFTTT
Postremission sequential monitoring of minimal residual disease by WT1 Q-PCR and multiparametric flow cytometry assessment predicts relapse and may help to address risk-adapted therapy in acute myeloid leukemia patients
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 47 δευτερόλεπτα
Abstract Risk stratification in acute myeloid leukemia (AML) patients using prognostic parameters at diagnosis is effective, but may be significantly improved by the use of on treatment parameters which better define the actual sensitivity to therapy in the single patient. Minimal residual disease (MRD) monitoring has been demonstrated crucial for the identification of AML patients […]
Immunogenicity and clinical effectiveness of the trivalent inactivated influenza vaccine in immunocompromised children undergoing treatment for cancer
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 47 δευτερόλεπτα
Abstract Influenza is associated with significant morbidity and mortality in children receiving therapy for cancer, yet recommendation for, and uptake of the seasonal vaccine remains poor. One hundred children undergoing treatment for cancer were vaccinated with the trivalent inactivated influenza vaccine according to national guidelines in 2010 and 2011. Influenza-specific hemagglutinin inhibition antibody titers were […]
Brèves de l’AERIO
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 47 δευτερόλεπτα
from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1YNuyG7 via IFTTT
Short stature, wasting of the soft tissue of the arms and legs, erythematous skin eruptions and a prominent abdomen due to hepatosplenomegaly. Generalized microdontia, confirmed by tooth measurement and osteopenia of her jaws
CANDLE SYNDROME: Orodfacial manifestations and dental implications: AbstractA South African girl with CANDLE Syndrome is reported with emphasis on the orodental features and dental management. Clinical manifestations included short stature, wasting of the soft tissue of the arms and legs, erythematous skin eruptions and a prominent abdomen due to hepatosplenomegaly. Generalized microdontia, confirmed by tooth measurement and osteopenia of her jaws, confirmed by digitalized radiography, were previously undescribed syndromic components. Intellectual impairment posed problems during d... περισσότερα »
Detecting Residual/Recurrent Head Neck Squamous Cell Carcinomas
Detecting Residual/Recurrent Head Neck Squamous Cell Carcinomas Using PET or PET/CT: Systematic Review and Meta-analysis: Objective To evaluate the diagnostic accuracy of positron emission tomography (PET) and PET/computed tomography (CT) for detecting residual and/or recurrent local and regional disease and distant metastases in patients with head and neck squamous cell carcinomas (HNSCCs) following radiotherapy with or without chemotherapy. Data Sources A systematic review with no language restrictions was conducted using PREMEDLINE, MEDLINE, EMBASE, and Google Scholar. Review M... περισσότερα »
Anti-inflammatory and lymphangiogenetic effects of low-level laser therapy on lymphedema
Anti-inflammatory and lymphangiogenetic effects of low-level laser therapy on lymphedema in an experimental mouse tail model: AbstractThe aim of the present study was to investigate the therapeutic mechanism of low-level laser therapy (LLLT) in the mouse tail lymphedema model. Six-week-old female mice were classified into the laser treatment group, sham treatment group, and surgical control group (10 mice per group). LLLT was administered daily for 10 min from the surgical day to 11 days (12 times). Macrophage activation and lymphatic vessel regeneration were evaluated through immu...περισσότερα »
High intensity laser therapy in lateral epicondylitis
Long term effects of high intensity laser therapy in lateral epicondylitis patients: AbstractThe objective of this study is to investigate short- and long-term effects of high-intensity laser therapy (HILT) in lateral epicondylitis (LE) patients. Thirty patients with LE diagnosis (23 unilateral and 7 bilateral in total 37 elbows) were treated using HILT. LE patients were evaluated before, right after, and 6 months following HILT intervention post-treatment using visual analogue scale for pain (VAS) during activity and resting. Disabilities of the Arm, Shoulder, and Hand (DASH) Scor... περισσότερα »
Effects of Steady-State Noise on Verbal Working Memory in Young Adults
Effects of Steady-State Noise on Verbal Working Memory in Young Adults: Purpose We set out to examine the impact of perceptual, linguistic, and capacity demands on performance of verbal working-memory tasks. The Ease of Language Understanding model (Rönnberg et al., 2013) provides a framework for testing the dynamics of these interactions within the auditory-cognitive system. Methods Adult native speakers of English (n = 45) participated in verbal working-memory tasks requiring processing and storage of words involving different linguistic demands (closed/open set). Capacity deman...περισσότερα »
Tinnitus Suicide
Tinnitus Suicide: Tinnitus can be a difficult condition to live with because it can impact you on a daily basis and prevent you from leading a normal life. The most basic definition of this condition is a ringing sound in the ears, but it can also be heard as static, buzzing, screeching, roaring, hissing or other sounds. For some, the sound may be quiet and intermittent. For others, it may be constant and loud. This can interfere with your ability to sleep, work and participate in other normal activities. Because it can have a dramatic impact on your quality of life, you may wonder... περισσότερα »
Vocal Performance Teachers and Hearing Loss
Vocal Performance Teachers and Hearing Loss: Hearing thresholds and distortion product otoacoustic emissions were measured for teachers of vocal performance who were gathered for a national conference. Results showed mean audiometric thresholds to be consistent with noise induced hearing loss, more than what would be expected with normal aging. Years of instruction and age were considered as factors in the hearing loss observed. It was concluded that hearing conservation should be initiated with this group to help raise awareness and protect them from hearing loss due to occupationa...περισσότερα »
Health-related quality of life in locally advanced cervical cancer patients after definitive radio(chemo)t herapy including image guided adaptive brachytherapy – An analysis from the EMBRACE study
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 50 δευτερόλεπτα
Publication date: Available online 29 December 2015 Source:International Journal of Radiation Oncology*Biology*Physics Author(s): Kathrin Kirchheiner, Richard Pötter, Kari Tanderup, Jacob C. Lindegaard, Christine Haie-Meder, Primož Petrič, Umesh Mahantshetty, Ina M. Jürgenliemk-Schulz, Bhavana Rai, Rachel Cooper, Wolfgang Dörr, Remi A. Nout PurposeThis analysis aims to evaluate functioning and symptom scores in longitudinal quality of life (QoL) […]
High-Dose, Single-Fraction Irradiation Rapidly Reduces Tumor Vasculature and Perfusion in a Xenograft Model of Neuroblastoma
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 50 δευτερόλεπτα
Publication date: Available online 29 December 2015 Source:International Journal of Radiation Oncology*Biology*Physics Author(s): Ashish Jani, Fauzia Shaikh, Sunjay Barton, Callen Willis, Debarshi Banerjee, Jason Mitchell, Sonia L. Hernandez, Tom Hei, Angela Kadenhe-Chiweshe, Darrell J. Yamashiro, Eileen P. Connolly PurposeTo characterize the effects of high dose radiation therapy (HDRT) on neuroblastoma tumor vasculature, including the endothelial […]
Changes in the body image of bone sarcoma survivors following surgical treatment—A qualitative study
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 50 δευτερόλεπτα
Background and Objectives Among several long-term effects, people treated for cancer may experience an altered appearance. Our study aims to identify how visible body changes following surgical treatment affect the life and identity of primary bone sarcoma survivors 3–10 years after diagnosis. A qualitative, phenomenological, and hermeneutic design was applied. Methods Sarcoma survivors (n = 18) who […]
Simplifying Blepharoplasty
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 50 δευτερόλεπτα
Learning Objectives: After reading this article, the participant should be able to: 1. Identify pertinent eyelid and periorbital anatomical structures when evaluating a patient for blepharoplasty. 2. Adequately evaluate a patient by performing a focused history-taking and medical examination tailored for the aging eyelid patient. 3. Identify the aging changes that have occurred, and determine […]
Discussion: The Impact of Radiation Therapy, Lymph Node Dissection, and Hormonal Therapy on Outcomes of Tissue Expander–Implant Exchange in Prosthetic Breast Reconstruction
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 50 δευτερόλεπτα
No abstract available from #ORL-AlexandrosSfakianakis via ola Kala on Inoreader http://ift.tt/1UfWtrE via IFTTT
ASPS/PSF Sponsored Symposia and Workshops
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 50 δευτερόλεπτα
No abstract available from #ORL-AlexandrosSfakianakis via ola Kala on Inoreader http://ift.tt/1mQ0vwk via IFTTT
The Impact of Travel Distance on Breast Reconstruction in the United States
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 50 δευτερόλεπτα
Background: Inadequate access to breast reconstruction was a motivating factor underlying passage of the Women’s Health and Cancer Rights Act. It remains unclear whether all patients interested in breast reconstruction undergo this procedure. The aim of this study was to determine whether geographic disparities are present that limit the rate and method of postmastectomy reconstruction. […]
Corrigendum
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 50 δευτερόλεπτα
from #ORL-AlexandrosSfakianakis via ola Kala on Inoreader http://ift.tt/1SlH4HN via IFTTT
Action-outcome relationships are represented differently by medial prefrontal and orbitofrontal cortex neurons during action execution
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 50 δευτερόλεπτα
Internal representations of action-outcome relationships are necessary for flexible adaptation of motivated behavior in dynamic environments. Prefrontal cortex (PFC) is implicated in flexible planning and execution of goal-directed actions, but little is known about how information about action-outcome relationships is represented across functionally distinct regions of PFC. Here, we observe distinct patterns of action-evoked single […]
The use of Tisseal™ fibrin glue in the management of chronic oro-cutaneous fistula in the radiotherapy treated neck – a technical note
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 50 δευτερόλεπτα
Fibrin glue is used successfully in many areas of surgery to facilitate wound healing, and to reduce perioperative bleeding and postoperative scarring. In the head and neck it can be beneficial after resection of oral cancer and neck dissection,1 and in the treatment of sialoceles and refractory parotid fistulas.2 It is also showing promise in […]
Aural Rehabilitation
Standardized Patients: Potential to Improve Student Training in Aural Rehabilitation: Hearing loss is a growing public health concern. The multifaceted consequences of hearing loss are far reaching and include reduced audibility, well-being, and quality-of-life. Audiologists require specific training to address the wide range of hearing loss (re)habilitation needs, including some of the psychosocial needs of patients. One instructional method that might provide valuable training for the next generation of clinicians is the use of simulated or standardized patients (SPs). Standardize... περισσότερα »
Amelogenin Exon4 Forms a Novel miRNA That Directs Ameloblast and Osteoblast Differentiation
Amelogenins constitute the major portion of secretory enamel matrix proteins and are known to be highly alternative spliced. Of all the alternatively spliced forms of amelogenins, exon4 is most commonly spliced out. Our analyses of the exon4 sequence led us to hypothesize that when spliced out, exon4 may generate a novel mature miRNA. To explore this possibility, we used in vivo mouse models (wild-type and *Amel* knockout mice) and in vitro cell culture to investigate the presence and function of a mature miRNA derived from exon4 (miR-exon4). When ameloblast-like cells (LS8) were ...περισσότερα »
Discussion: Carbon Dioxide versus Saline Tissue Expanders: Does It Matter?
No abstract available from #Aesthetics via alexandrossfakianakis on Inoreader http://ift.tt/1UfWqvR via IFTTT
Discussion: A Systematic Review and Meta-Analysis of Perforator-Pedicled Propeller Flaps in Lower Extremity Defects: Identification of Risk Factors for Complications
[image: image]No abstract available from #Aesthetics via alexandrossfakianakis on Inoreader http://ift.tt/1UfWtaU via IFTTT
A Systematic Review of Comparison of Autologous, Allogeneic, and Synthetic Augmentation Grafts in Nipple Reconstruction
[image: image]Background: Many techniques have been described for nipple reconstruction, with the principal limitation being excessive loss of projection. The ideal reconstructed nipple provides sustained projection, the fewest complications, and high levels of patient satisfaction. A variety of materials are available for projection augmentation, including autologous, allogeneic, and synthetic materials. To date, there has been no systematic review to study the efficacy, projection, and complication rates of different materials used in nipple reconstruction. Methods: MEDLINE, Embas... περισσότερα »
Discussion: A Methodology for Determining Standard of Care Status for a New Surgical Procedure: Hand Transplantation
No abstract available from #Aesthetics via alexandrossfakianakis on Inoreader http://ift.tt/1QWYgEl via IFTTT
Postremission sequential monitoring of minimal residual disease by WT1 Q-PCR and multiparametric flow cytometry assessment predicts relapse and may help to address risk-adapted therapy in acute myeloid leukemia patients
Abstract Risk stratification in acute myeloid leukemia (AML) patients using prognostic parameters at diagnosis is effective, but may be significantly improved by the use of on treatment parameters which better define the actual sensitivity to therapy in the single patient. Minimal residual disease (MRD) monitoring has been demonstrated crucial for the identification of AML patients… Continue reading Postremission sequential monitoring of minimal residual disease by WT1 Q-PCR and multiparametric flow cytometry assessment predicts relapse and may help to address risk-adapted therapy i... περισσότερα »
Lymphangiohemangioma of buccal mucosa: Report of a rare case
Publication date: Available online 29 December 2015 Source:Journal of Oral and Maxillofacial Surgery, Medicine, and Pathology Author(s): Fateme Yarmand, Maryam Seyyedmajidi, Atena Shirzad, Ramin Foroughi, Aliasghar Bakhshian Vascular anomalies are divided in two groups of vascular tumors and vascular malformation. Hemangioma and lymphangioma are both examples of vascular tumors. Hemangiomas are known as proliferative vascular… Continue reading Lymphangiohemangioma of buccal mucosa: Report of a rare case
ASPS/PSF Sponsored Symposia and Workshops
No abstract available from #ORL-AlexandrosSfakianakis via ola Kala on Inoreader http://ift.tt/1mQ0vwk via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1NVc7EQ via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1OwWKYU via IFTTT
Immunogenicity and clinical effectiveness of the trivalent inactivated influenza vaccine in immunocompromised children undergoing treatment for cancer
Abstract Influenza is associated with significant morbidity and mortality in children receiving therapy for cancer, yet recommendation for, and uptake of the seasonal vaccine remains poor. One hundred children undergoing treatment for cancer were vaccinated with the trivalent inactivated influenza vaccine according to national guidelines in 2010 and 2011. Influenza-specific hemagglutinin inhibition antibody titers were… Continue reading Immunogenicity and clinical effectiveness of the trivalent inactivated influenza vaccine in immunocompromised children undergoing treatment for cancer
Facial nerve paralysis following endodontic treatment of lower first molar
Publication date: Available online 29 December 2015 Source:Journal of Oral and Maxillofacial Surgery, Medicine, and Pathology Author(s): Umut Demetoglu, Gokhan Ozkan, Hasan Onur Simsek Facial nerve palsy is a common cranial nerve disorder that affects facial mimic movements. Mostly, it is caused by idiopathic conditions, such as trauma or tumors located in parotid gland. Facial… Continue reading Facial nerve paralysis following endodontic treatment of lower first molar
Parity and thyroid cancer risk: a meta-analysis of epidemiological studies
Abstract Although observational studies have assessed the relationship between parity and thyroid cancer risk, the findings are inconsistent. To quantitatively assess the association, we conducted a systematic review and meta-analysis. PubMed and Embase were searched up to January 2015. Prospective or case–control studies that evaluated the association between parity and thyroid cancer risk were included.… Continue reading Parity and thyroid cancer risk: a meta-analysis of epidemiological studies
A supported psychoeducational intervention to improve family mental health following discharge from paediatric intensive care: feasibility and pilot randomised controlled trial
Objective To assess feasibility and pilot a supported psychoeducational tool to improve parent and child mental health following discharge from a paediatric intensive care unit (PICU), in preparation for a large randomised controlled trial (RCT). Design Feasibility assessment and single-centre, parallel group, pilot RCT. A concealed computer generated list was used to randomise participants, with… Continue reading A supported psychoeducational intervention to improve family mental health following discharge from paediatric intensive care: feasibility and pilot randomised controlled ... περισσότερα »
Pediatric phase I trial of oral sorafenib and topotecan in refractory or recurrent pediatric solid malignancies
Abstract Targeted kinase inhibitors and camptothecins have shown preclinical and clinical activity in several cancers. This trial evaluated the maximum tolerated dose (MTD) and dose-limiting toxicities of sorafenib and topotecan administered orally in pediatric patients with relapsed solid tumors. Sorafenib was administered twice daily and topotecan once daily on days 1–5 and 8–12 of each… Continue reading Pediatric phase I trial of oral sorafenib and topotecan in refractory or recurrent pediatric solid malignancies
Two decades of external peer review of cancer care in general hospitals; the Dutch experience
Abstract External peer review was introduced in general hospitals in the Netherlands in 1994 to assess and improve the multidisciplinary team approach in cancer care. This paper aims to explore the value, perceived impact, and (future) role of external peer review in cancer care. Semistructured interviews were held with clinicians, oncology nurses, and managers from… Continue reading Two decades of external peer review of cancer care in general hospitals; the Dutch experience
Influence of ICU-bed availability on ICU admission decisions
Background: The potential influence of bed availability on triage to intensive care unit (ICU) admission is among the factors that may influence the ideal ratio of ICU beds to population: thus, high bed availability (HBA) may result in the admission of patients too well or too sick to benefit, whereas bed scarcity may result in… Continue reading Influence of ICU-bed availability on ICU admission decisions
High-Dose, Single-Fraction Irradiation Rapidly Reduces Tumor Vasculature and Perfusion in a Xenograft Model of Neuroblastoma
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 1 ώρα
Publication date: Available online 29 December 2015 Source:International Journal of Radiation Oncology*Biology*Physics Author(s): Ashish Jani, Fauzia Shaikh, Sunjay Barton, Callen Willis, Debarshi Banerjee, Jason Mitchell, Sonia L. Hernandez, Tom Hei, Angela Kadenhe-Chiweshe, Darrell J. Yamashiro, Eileen P. Connolly PurposeTo characterize the effects of high dose radiation therapy (HDRT) on neuroblastoma tumor vasculature, including the endothelial […]
A retrospective analysis of treatment-related hospitalization costs of pediatric, adolescent, and young adult acute lymphoblastic leukemia
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 1 ώρα
Abstract This retrospective study examined the longitudinal hospital outcomes (costs adjusted for inflation, hospital days, and admissions) associated with the treatment of pediatric, adolescent, and young adult acute lymphoblastic leukemia (ALL). Patients between one and 26 years of age with newly diagnosed ALL, who were treated at Primary Children’s Hospital (PCH) in Salt Lake City, […]
Health-related quality of life in locally advanced cervical cancer patients after definitive radio(chemo)t herapy including image guided adaptive brachytherapy – An analysis from the EMBRACE study
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 1 ώρα
Publication date: Available online 29 December 2015 Source:International Journal of Radiation Oncology*Biology*Physics Author(s): Kathrin Kirchheiner, Richard Pötter, Kari Tanderup, Jacob C. Lindegaard, Christine Haie-Meder, Primož Petrič, Umesh Mahantshetty, Ina M. Jürgenliemk-Schulz, Bhavana Rai, Rachel Cooper, Wolfgang Dörr, Remi A. Nout PurposeThis analysis aims to evaluate functioning and symptom scores in longitudinal quality of life (QoL) […]
Retrospective analysis of systemic chemotherapy and total parenteral nutrition for the treatment of malignant small bowel obstruction
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 1 ώρα
Abstract Malignant small bowel obstruction (MSBO) that does not resolve with conservative measures frequently leaves few treatment options other than palliative care. This single-institution retrospective study assesses the outcomes of a more aggressive approach—concurrent systemic chemotherapy and total parenteral nutrition (TPN)—in the treatment of MSBO. The MD Anderson pharmacy database was queried to identify patients […]
Changes in the body image of bone sarcoma survivors following surgical treatment—A qualitative study
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 1 ώρα
Background and Objectives Among several long-term effects, people treated for cancer may experience an altered appearance. Our study aims to identify how visible body changes following surgical treatment affect the life and identity of primary bone sarcoma survivors 3–10 years after diagnosis. A qualitative, phenomenological, and hermeneutic design was applied. Methods Sarcoma survivors (n = 18) who […]
KRAS mutation in lung metastases from colorectal cancer: prognostic implications
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 1 ώρα
Abstract KRAS mutant colorectal cancer (CRC) patients develop lung and brain metastases more frequently than KRAS wild-type (WT) counterpart. We retrospectively investigated the prognostic role of KRAS, BRAF, and PIK3CA (exon 20) mutations and loss of phosphatase and tensin homolog (PTEN) in surgically resected lung metastases. Lung specimens from 75 metastatic CRC (mCRC) patients treated […]
Simplifying Blepharoplasty
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 1 ώρα
Learning Objectives: After reading this article, the participant should be able to: 1. Identify pertinent eyelid and periorbital anatomical structures when evaluating a patient for blepharoplasty. 2. Adequately evaluate a patient by performing a focused history-taking and medical examination tailored for the aging eyelid patient. 3. Identify the aging changes that have occurred, and determine […]
Targeting the PI3K signaling pathway in KRAS mutant colon cancer
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 1 ώρα
Abstract Metastatic colorectal cancer (CRC) patients with v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog (KRAS) mutations are resistant to monoclonal antibody that targets the epidermal growth factor receptor such as cetuximab. BKM120 targets phosphatidylinositide-3-kinase (PIK3CA), but it is unknown whether BKM120 can reverse cetuximab resistance in KRAS mutant CRC. Human CRC cell lines with KRAS […]
Discussion: The Impact of Radiation Therapy, Lymph Node Dissection, and Hormonal Therapy on Outcomes of Tissue Expander–Implant Exchange in Prosthetic Breast Reconstruction
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 1 ώρα
No abstract available from #ORL-AlexandrosSfakianakis via ola Kala on Inoreader http://ift.tt/1UfWtrE via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1OjZffa via IFTTT
Postremission sequential monitoring of minimal residual disease by WT1 Q-PCR and multiparametric flow cytometry assessment predicts relapse and may help to address risk-adapted therapy in acute myeloid leukemia patients
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 1 ώρα
Abstract Risk stratification in acute myeloid leukemia (AML) patients using prognostic parameters at diagnosis is effective, but may be significantly improved by the use of on treatment parameters which better define the actual sensitivity to therapy in the single patient. Minimal residual disease (MRD) monitoring has been demonstrated crucial for the identification of AML patients […]
Microglial/Macrophage Polarization Dynamics following Traumatic Brain Injury
Journal of Neurotrauma , Vol. 0, No. 0. from Neurology via xlomafota13 on Inoreader http://ift.tt/1VoYAdX via IFTTT
Microglial/Macrophage Polarization Dynamics following Traumatic Brain Injury
Journal of Neurotrauma , Vol. 0, No. 0. from Neurology via xlomafota13 on Inoreader http://ift.tt/1VoYAdX via IFTTT
Through the Looking Glass: Real-Time Video Using ‘Smart’ Technology Provides Enhanced Intraoperative Logistics
Abstract Introduction In the setting of increasingly complex medical therapies and limited physician resources, the recent emergence of 'smart' technology offers tremendous potential for improved logistics, efficiency, and communication between medical team members. In an effort to harness these capabilities, we sought to evaluate the utility of this technology in surgical practice through the employment of a wearable camera device during cardiothoracic organ recovery. Methods A single procurement surgeon was trained for use of an Explorer Edition Google Glass™ (Google Inc., Moun... περισσότερα »
Minimally Invasive Versus Open Total Gastrectomy for Gastric Cancer: A Systematic Review and Meta-analysis of Short-Term Outcomes and Completeness of Resection
Abstract Minimally invasive surgical techniques for gastric cancer are gaining more acceptance worldwide as an alternative to open resection. In order to assess the role of minimally invasive and open techniques in total gastrectomy for cancer, a systematic review and meta-analysis was performed. Articles comparing minimally invasive versus open total gastrectomy were reviewed, collected from the Medline, Embase, and Cochrane databases. Two different authors (JS and NW) independently selected and assessed the articles. Outcomes regarding operative results, postoperative recovery, ...περισσότερα »
The Effectiveness of Radioactive Iodine Remnant Ablation for Papillary Thyroid Microcarcinoma: A Systematic Review and Meta-analysis
Abstract Background This systematic review and meta-analysis aimed to evaluate the effectiveness of radioactive iodine (RAI) remnant ablation for thyroid cancer-related outcomes of patients with papillary thyroid microcarcinoma (PTMC). Methods A systematic literature search of PubMed, EMBASE OvidSP, and EBSCO was conducted. Studies were selected that provided multivariable analysis of the effectiveness of RAI ablation or provided specific data of a 10 years history of thyroid cancer-related outcomes in patients that presented with PTMC. Results Nineteen studies met the inclusio...περισσότερα »
Vital Statistics: Estimating Injury Mortality in Kigali, Rwanda
Abstract Background Globally, injury deaths largely occur in low- and middle-income countries. No estimates of injury-associated mortality exist in Rwanda. This study aimed to describe the patterns of injury-related deaths in Kigali, Rwanda using existing data sources. Methods We created a database of all deaths reported by the main institutions providing emergency care in Kigali—four major hospitals, two divisions of the Rwanda National Police, and the National Emergency Medical Service—during 12 months (Jan–Dec 2012) and analyzed it for demographics, diagnoses, mechanism and ty...περισσότερα »
Risk Factors and Clinical Outcomes of Recurrent Laryngeal Nerve Paralysis After Esophagectomy for Thoracic Esophageal Carcinoma
Abstract Background The objectives of this study were to assess the incidence of recurrent laryngeal nerve paralysis (RLNP) using laryngoscopy after esophagectomy for thoracic esophageal carcinoma and to clarify the risk factors influencing postoperative RLNP. Methods A total of 299 patients who underwent laryngoscopic examination after esophagectomy were retrospectively reviewed. Patients who were found to have postoperative RLNP were followed up every 1–3 months, with a median follow-up period of 3 months. Recovery from paralysis was also evaluated on the basis of each affected... περισσότερα »
Does the Frequency of Cholecystectomy Affect the Ensuing Incidence of Gallbladder Cancer in Sweden? A Population-Based Study with a 16-Year Coverage
Abstract Background Gallbladder cancer (GBC) is rare among the different gastrointestinal cancers with a significant global variation in incidence. High cholecystectomy rates on benign indications have been assumed to prevent the development of gallbladder cancer. The aim of the present study was to explore the relationship between the rate of cholecystectomy at different time periods and regions of the country and the annual incidence of GBC. Methods Standardized cholecystectomy and GBC incidences for Swedish counties have been obtained from the Swedish national inpatient and Nat... περισσότερα »
Intraoperative Contrast-Enhanced Ultrasound in Colorectal Liver Metastasis Surgery Improves the Identification and Characterization of Nodules
Abstract Introduction The sensitivity of preoperative assessment of colorectal liver metastases (CRLM) ranges from 74 to 80 %. Intraoperative ultrasound (IOUS) associated with contrast-enhanced intraoperative ultrasound (CE-IOUS) may be able to improve this. Thus, the aims of this study were to assess the value of IOUS and CE-IOUS for the surgical approach and to determine risk factors both for the detection of new nodules and for the modification of the surgical strategy. Materials and methods Forty-three patients who underwent CRLM surgery were included. These patients had an M... περισσότερα »
A Randomised Assessment of Trainee Doctors’ Understanding and Interpretation of Diagnostic Test Results
Abstract Introduction Doctors are unfamiliar with diagnostic accuracy parameters despite routine clinical use of diagnostic tests to estimate disease probability. Methods Trainee doctors completed a questionnaire exploring their understanding of diagnostic accuracy parameters; ability to calculate post-test probability of a common surgical condition (appendicitis) and their perceptions on training in this area. To determine whether the method of information provision altered interpretation, trainees were randomised to receive diagnostic test information in three ways: positive tes... περισσότερα »
Evaluation of 64-Channel Contrast-Enhanced Multi-detector Row Computed Tomography for Preoperative N Staging in cT2-4 Gastric Carcinoma
Abstract Background Preoperative N staging is essential for the best treatment planning in patients with gastric carcinoma. The aim of this study was to evaluate the accuracy of preoperative N staging using contrast-enhanced multi-detector row computed tomography (CE-MDCT) in patients with resectable cT2-4 gastric carcinoma. Methods A total of 218 patients who underwent a gastrectomy with D2 lymphadenectomy for previously untreated cT2-4 primary gastric carcinoma were studied. Preoperative N staging was performed according to the 7th (UICC) TNM Staging System using pre-specified ... περισσότερα »
Risk of Complications with Energy-Based Surgical Devices in Thyroid Surgery: A National Multicenter Register Study
Abstract Background Energy-based surgical devices (EBD) combining cutting and coagulation are increasingly used in thyroid surgery. However, there is a lack of information about potential benefits and risk of complications outside controlled trials. The aims of this national multicenter register study were to describe the use of EDB, their potential effect on complication rates, and on operation time. Materials and methods The Scandinavian Quality Register for Thyroid and Parathyroid surgery includes 35 surgical units in Sweden and covered 88 % of the thyroid procedures performed...περισσότερα »
Fusion of Information from 3D Printing and Surgical Robot: An Innovative Minimally Technique Illustrated by the Resection of a Large Celiac Trunk Aneurysm
Abstract The rapid advancement in technological innovations, such as 3D printing and robotic surgery, is a progression that few could imagine just a few years ago. The combination of these technologies namely 3D printing of patient-specific anatomy and robotic surgery is reported here to plan and perform the resection of a large aneurysm of the celiac trunk. from NeuroSurgery via xlomafota13 on Inoreader http://ift.tt/1OjA7Fz via IFTTT
Surgery and Obstetric Care are Highly Cost-Effective Interventions in a Sub-Saharan African District Hospital: A Three-Month Single-Institution Study of Surgical Costs and Outcomes
Abstract Background The Lancet recently sponsored a commission examining the role of surgery in global health. There is a paucity of published information on the cost-effectiveness of surgery in low- and middle-income countries, a key metric in the prioritisation of limited resources. Methods All patients undergoing emergency laparotomy, elective and emergency inguinal hernia repair, elective and emergency caesarean section, amputation, fracture manipulation, or fracture fixation over a 3 months period in a single district African hospital were assessed. World Health Organisation... περισσότερα »
Effect of Glyceryl Trinitrate Ointment on Pain Control After Hemorrhoidectomy: A Meta-analysis of Randomized Controlled Trials
Abstract Background Hemorrhoidectomy is associated with postoperative pain and prolonged wound healing. Glyceryl trinitrate has been shown to decrease muscle spasm and increase anodermal blood flow. A meta-analysis of randomized controlled trials was conducted to evaluate the efficacy of topical glyceryl trinitrate application in pain relief after hemorrhoidectomy. Methods PubMed, EMBASE, Cochrane Library, Scopus, and ClinicalTrials.gov registries were searched for studies published before August 2015. Individual effect sizes were standardized, and a meta-analysis was conducted to... περισσότερα »
Duration of Smoking Cessation and Postoperative Morbidity After Esophagectomy for Esophageal Cancer: How Long Should Patients Stop Smoking Before Surgery?
Abstract Background Smoking is one of the risk factors for postoperative morbidity. There were no studies on the correlation between the duration of smoking cessation and the incidence of morbidities after esophagectomy. Methods A total of 246 patients undergoing elective esophagectomy with 2- or 3-field lymphadenectomy for esophageal cancer between April 2005 and February 2015 were retrospectively analyzed. Patients were divided into five groups according to the duration of smoking cessation [no smoking cessation (including cessation for a few days), cessation for 7–30, 31–90, ≥... περισσότερα »
Mentorship as Experienced by Women Surgeons in Japan
Abstract Background Women have accounted for over 30 % of new medical students since 1995 in Japan. Establishing support systems for women surgeons to continue their work is a major issue in Japan. Mentorship can be one of the most effective means to help women surgeons to continue their work. The purpose of this study was to clarify the current status of mentorship among Japanese women surgeons and to discuss the role of mentors for women surgeons. Methods Invitation letters were sent to all female members of the Japan Association of Women Surgeons in April 2011. An 84-item quest...περισσότερα »
Risk Factors and Managements of Bile Leakage After Hepatectomy
Abstract Background The purpose of this study was to retrospectively determine the risk factors and evaluate the management of bile leakage. Methods Three hundred and thirty-four patients who underwent hepatectomy for Child classification grade A liver disease, without biliary reconstruction and laparoscopic procedures, between 2003 and 2013 were included. Risk factors were identified using multivariate analysis. Results Bile leakage was observed in 30 (9.0 %) patients. Multivariate analysis demonstrated that type of hepatectomy (segmentectomy 1, medial sectionectomy, anterior s... περισσότερα »
The NOTCH3 score: a pre-clinical CADASIL biomarker in a novel human genomic NOTCH3 transgenic mouse model with early progressive vascular NOTCH3 accumulation
Abstract Introduction CADASIL (Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy) is a hereditary small vessel disease caused by mutations in the *NOTCH3* gene, leading to toxic NOTCH3 protein accumulation in the small- to medium sized arterioles. The accumulation is systemic but most pronounced in the brain vasculature where it leads to clinical symptoms of recurrent stroke and dementia. There is no therapy for CADASIL, and therapeutic development is hampered by a lack of feasible clinical outcome measures and biomarkers, both in mouse mode... περισσότερα »
Unknown Organism/hand print palm
Organism was seen on the palm of a hand print done on MH. The large center portion of the colony, possible Bacillus, was round and mucoid, would drip if the plate was tilted. The organism spread from the center through rhizoid growth, what looks like a network of branching channels forming rhi... from Infection via ola Kala on Inoreader http://ift.tt/1YRxY5p via IFTTT
Unknown Organism/hand print
Unknown organism seen on the tip of a finger imprint done on MH. The colony, possible bacillus, was dry/mat throughout the colony. There were 3 pouches of liquid that can be seen in the colony. When the plate was tilted the liquid portion moved but did not break free from the membrane surroun... from Infection via ola Kala on Inoreader http://ift.tt/1JeNMgL via IFTTT
Advances in Tuberculosis Research: A Blueprint for Opportunities
from #Infections via alexandrossfakianakis on Inoreader http://ift.tt/1mp1hji via IFTTT
Insertion of percutaneous endoscopic gastrostomy by head and neck surgeons: systematic review
Percutaneous endoscopic gastrostomy to maintain nutrition in patients with cancer of the head and neck is increasingly being done by head and neck surgeons. We have reviewed published papers to assess the success rate of insertion and the incidence of complications. from OroFacial Medicine via ola Kala on Inoreader http://ift.tt/1OjOidM via IFTTT
The use of Tisseal™ fibrin glue in the management of chronic oro-cutaneous fistula in the radiotherapy treated neck – a technical note
Fibrin glue is used successfully in many areas of surgery to facilitate wound healing, and to reduce perioperative bleeding and postoperative scarring. In the head and neck it can be beneficial after resection of oral cancer and neck dissection,1 and in the treatment of sialoceles and refractory parotid fistulas.2 It is also showing promise in orthopaedics, as its angiogenic and osteogenic properties can improve perfusion in femoral avascular necrosis.3,4 from OroFacial Medicine via ola Kala on Inoreader http://ift.tt/1ToFfrL via IFTTT
Image-guided nasal endoscopic drainage of an orbital superior subperiosteal abscess
A 48-year-old woman presented to the emergency department with swelling and erythema of the right upper eyelid for 4 days. Computed tomography showed a superiorly-based subperiosteal orbital abscess together with paranasal sinusitis. She was managed medically, but symptoms did not improve, so we drained the abscess using image-guided intranasal endoscopy. Her symptoms began to improve 2 days after drainage, and her recovery was uneventful. Drainage of an orbital subperiosteal abscess should be considered if there are ophthalmological symptoms such as visual disturbances, raised in... περισσότερα »
Reconstruction of low hairline microtia of Treacher Collins syndrome with a hinged mastoid fascial flap
Treacher Collins syndrome (TCS) is a rare genetic disorder leading to congenital craniofacial malformations. Although this syndrome presents with various symptoms, corrective surgery for bilateral microtia with low hairline is one of the most challenging operations given the complex contours of the external ear. In this technical note, a novel, simple procedure for dealing with the low hairline by using a hinged mastoid fascial flap simultaneously with costal cartilage grafting is described. Several techniques for the reconstruction of low hairline microtia have been reported prev... περισσότερα »
Safety and efficacy of tiotropium in patients switching from HandiHaler to Respimat in the TIOSPIR trial
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Objectives This post hoc analysis of TIOtropium Safety and Performance In Respimat (TIOSPIR) evaluated safety and exacerbation efficacy in patients with stable (≥2 months) use of tiotropium HandiHaler 18 µg (HH18) prior to study entry, to evaluate whether there was a difference in risk for patients who switched from HH18 to tiotropium Respimat 2.5 µg […]
Are primary care factors associated with hospital episodes for adverse drug reactions? A national observational study
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Objective Identification of primary care factors associated with hospital admissions for adverse drug reactions (ADRs). Design and setting Cross-sectional analysis of 2010–2012 data from all National Health Service hospitals and 7664 of 8358 general practices in England. Method We identified all hospital episodes with an International Classification of Diseases (ICD) 10 code indicative of an […]
Danish register-based study on the association between specific cardiovascular drugs and fragility fractures
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Objective To determine whether drugs used in treatment of cardiovascular diseases (CVD-drugs), including hypertension, increase the risk of fragility fractures in individuals above the age of 65 years. Design Retrospective nationwide cohort study. Setting Danish nationwide national registers. Participants All individuals in Denmark ≥65 years who used specified CVD-drugs in the study period between 1999 […]
A framework for the first-person internal sensation of visual perception in mammals and a comparable circuitry for olfactory perception in Drosophila
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Perception is a first-person internal sensation induced within the nervous system at the time of arrival of sensory stimuli from objects in the environment. Lack of access to the first-person properties has limited viewing perception as an emergent property and it is currently being studied using third-person observed findings from various levels. One feasible approach […]
Reproductive factors, tumor estrogen receptor status and contralateral breast cancer risk: results from the WECARE study
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Several reproductive factors are known to be associated with risk of breast cancer; however, relationships between these factors with risk of second primary asynchronous contralateral breast cancer (CBC) have not been widely studied. The Women’s Environmental, Cancer, and Radiation Epidemiology (WECARE) Study is a population-based case-control study of 1521 CBC cases and 2212 individually matched […]
Molecular cloning and expression analysis of KIN10 and cold-acclimation related genes in wild banana ‘Huanxi’ (Musa itinerans)
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Banana cultivars may experience chilling or freezing injury in some of their cultivated regions, where wild banana can still grow very well. The clarification of the cold-resistant mechanism of wild banana is vital for cold-resistant banana breeding. In this study, the central stress integrator gene KIN10 and some cold-acclimation related genes (HOS1 and ICE1s) from […]
Impact of preoperative extracorporeal membrane oxygenation on vasoactive inotrope score after implantation of left ventricular assist device
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
The purpose of this study was to elucidate the difference in inotrope use between patients who underwent left ventricular assist device (LVAD) implantation with preoperative extracorporeal membrane oxygenation (ECMO) and those who underwent LVAD implantation without preoperative ECMO. One hundred and eight patients who underwent LVAD implantation were enrolled in this study. Prior to LVAD […]
Modulation of post-stroke degenerative and regenerative processes and subacute protection by site-targeted inhibition of the alternative pathway of complement
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Background: Complement promotes neuroinflammation and injury in models of stroke. However, complement is also being increasingly implicated in repair and regeneration after central nervous system (CNS) injury, and some complement deficiencies have been shown to provide acute, but not subacute, protection after murine stroke. Here, we investigate the dual role of complement in injury and […]
Cardiac ACE2/angiotensin 1-7/Mas receptor axis is activated in thyroid hormone-induced cardiac hypertrophy
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Objectives: Thyroid hormone (TH) promotes marked effects on the cardiovascular system, including the development of cardiac hypertrophy. Some studies have demonstrated that the renin–angiotensin system (RAS) is a key mediator of the cardiac growth in response to elevated TH levels. Although some of the main RAS components are changed in cardiac tissue on hyperthyroid state, […]
Association of weight gain with coronary artery disease, inflammation and thrombogenicity
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Abstract Obese individuals, despite having increased cardiovascular (CV) risk factors experience adverse CV outcomes less frequently than non-obese. Little is known about association of long-term weight gain to development of coronary artery disease (CAD), inflammation and thrombogenicity. 418 consecutive patients with suspected CAD undergoing elective cardiac catheterization were included in a sub-analysis of the multi […]
A Systematic Review of Comparison of Autologous, Allogeneic, and Synthetic Augmentation Grafts in Nipple Reconstruction
sfakianakismedicsστοORL ALLERGY AESTHETICS ANATOMY Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 2 ώρες
Background: Many techniques have been described for nipple reconstruction, with the principal limitation being excessive loss of projection. The ideal reconstructed nipple provides sustained projection, the fewest complications, and high levels of patient satisfaction. A variety of materials are available for projection augmentation, including autologous, allogeneic, and synthetic materials. To date, there has been no […]
Discussion: A Methodology for Determining Standard of Care Status for a New Surgical Procedure: Hand Transplantation
sfakianakismedicsστοORL ALLERGY AESTHETICS ANATOMY Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 2 ώρες
No abstract available from Aesthetic via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1QWYgEl via IFTTT
Detection of Perforators Using Smartphone Thermal Imaging
sfakianakismedicsστοORL ALLERGY AESTHETICS ANATOMY Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 2 ώρες
Summary: Thermal imaging detects infrared radiation from an object, producing a thermogram that can be interpreted as a surrogate marker for cutaneous blood flow. To date, high-resolution cameras typically cost tens of thousands of dollars. The FLIR ONE is a smartphone-compatible miniature thermal imaging camera that currently retails at under $200. In a proof-of-concept study, […]
Reply: The Impact of Postoperative Expansion Initiation Timing on Breast Expander Capsular Characteristics: A Prospective Combined Clinical and Scanning Electron Microscopy Study
sfakianakismedicsστοORL ALLERGY AESTHETICS ANATOMY Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 2 ώρες
No abstract available from Aesthetic via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1ZAGeZL via IFTTT
Diced Cartilage Grafts Wrapped in Rectus Abdominis Fascia for Nasal Dorsum Augmentation
sfakianakismedicsστοORL ALLERGY AESTHETICS ANATOMY Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 2 ώρες
Background: Dorsum augmentation is one of the most delicate components of rhinoplasty. Although various solid grafts have been used in the past for this purpose, diced cartilage grafts wrapped in fascia have become popular in recent decades. In this study, the authors analyze and discuss the results of using diced cartilage grafts wrapped in rectus […]
Detection of Perforators Using Smartphone Thermal Imaging
[image: image]Summary: Thermal imaging detects infrared radiation from an object, producing a thermogram that can be interpreted as a surrogate marker for cutaneous blood flow. To date, high-resolution cameras typically cost tens of thousands of dollars. The FLIR ONE is a smartphone-compatible miniature thermal imaging camera that currently retails at under $200. In a proof-of-concept study, patients and healthy volunteers were assessed with thermal imaging for (1) detecting and mapping perforators, (2) defining perforasomes, and (3) monitoring free flaps. Preoperative, intraoperativ...περισσότερα »
Reply: The Impact of Postoperative Expansion Initiation Timing on Breast Expander Capsular Characteristics: A Prospective Combined Clinical and Scanning Electron Microscopy Study
[image: image]No abstract available from #Aesthetics via alexandrossfakianakis on Inoreader http://ift.tt/1ZAGeZL via IFTTT
Diced Cartilage Grafts Wrapped in Rectus Abdominis Fascia for Nasal Dorsum Augmentation
[image: image]Background: Dorsum augmentation is one of the most delicate components of rhinoplasty. Although various solid grafts have been used in the past for this purpose, diced cartilage grafts wrapped in fascia have become popular in recent decades. In this study, the authors analyze and discuss the results of using diced cartilage grafts wrapped in rectus abdominis muscle fascia for dorsal augmentation. Methods: Nasal dorsum augmentation using the diced cartilage wrapped in rectus abdominis fascia technique was performed on 109 patients between 2008 and 2014. Six patients wer...περισσότερα »
Negative Fine-Needle Aspiration in Patients with Goiter: Should We Doubt It?
Abstract Background Epidemiologic studies demonstrated higher incidence of thyroid cancer in patients with multinodular goiters compared to the general population. The aim of this study was to evaluate the risk of finding significant thyroid cancer in patients undergoing thyroidectomy for presumed benign disease. Methods The records of 273 patients operated for indications other than cancer or indeterminate cytology were reviewed and analyzed. Results 202 (74 %) patients had a preoperative fine-needle aspiration (FNA) performed. FNA was benign in 96 % of patients and non-diagnost... περισσότερα »
Bile Duct Injuries Associated With 55,134 Cholecystectomies: Treatment and Outcome from a National Perspective
Abstract Background Bile duct injury (BDI) is a rare complication associated with cholecystectomy, and recommendations for treatment are based on publications from referral centers with a selection of major injuries and failures after primary repair. The aim was to analyze the frequency, treatment, and outcome of BDIs in an unselected population-based cohort. Methods This was a retrospective cohort study including all BDIs registered in GallRiks (Swedish quality register for gallstone surgery and ERCP) during 2007–2011. Data for this study were based on a national follow-up survey...περισσότερα »
Long-Term Voice Outcomes After Robotic Thyroidectomy
Abstract Background The purpose of this study was to evaluate the long-term voice function after robotic thyroidectomy in comparison with conventional transcervical thyroidectomy. Methods We prospectively evaluated the voice functions of 54 patients with thyroid nodules who underwent robotic thyroidectomy by a gasless unilateral axillary or axillo-breast approach and of 70 patients who underwent conventional thyroidectomy. Subjective voice symptom score (VSS) was evaluated in questionnaires before thyroidectomy and then at 3, 6, 12, and 24 months after surgery. Objective acoustic... περισσότερα »
How Do Quality-of-Life and Gastrointestinal Symptoms Differ Between Post-cholecystectomy Patients and the Background Population?
Abstract Background Previous studies have indicated a correlation between indication for cholecystectomy and long-term gastrointestinal quality-of-life (QoL). The aim of the present study was to compare QoL in a post-cholecystectomy cohort with the background population and with historical controls. Methods A post-cholecystectomy study group (on average 4 years after cholecystectomy) was compared with a control group from the background population using the Gastrointestinal Quality-of-Life Index (GIQLI). EQ-5D scores were compared with expected scores derived from recent historica...περισσότερα »
