Antitumoral, antioxidant, and antimelanogenesis potencies of Hawthorn, a potential natural agent in the treatment of melanoma.
Antitumoral, antioxidant, and antimelanogenesis potencies of Hawthorn, a potential natural agent in the treatment of melanoma.: The lack of an efficient agent that does not have the disadvantage of low activity (kojic acid), high cytotoxicity, and mutagenicity (hydroquinone), poor skin penetration (arbutin), or low stability in formulation (glabridin) led us to continue our research on new antipigmentation/skin-lightening agents. Therefore, research of natural products that can modulate the metabolism of pigmentation is of great interest. Otherwise, malignant melanoma is one of the ... περισσότερα »
Minimally invasive video-assisted thyroidectomy (MIVAT)
Minimally invasive video-assisted thyroidectomy (MIVAT) from A to Z: AbstractA minimal access procedure does not necessarily mean that it is minimally invasive. However, as its name implies, MIVAT is a truly minimally invasive treatment modality. The advantages it offers over its conventional counterpart are indeed related to its minimally invasive nature. Furthermore, this nature has not compromised its ability to accomplish its purpose both safely and effectively. Ever since its introduction in the late 1990s, MIVAT has been progressively evolving. The indications for this proced... περισσότερα »
Cervicofacial Rhytidectomy After Radiotherapy
Cervicofacial Rhytidectomy After Radiotherapy: This medical record review evaluates the risk for complications of cervicofacial rhytidectomy in a cohort of adults who had undergone previous radiotherapy for head and neck cancer.
Dermal Regeneration Template for Full-Thickness Scalp Defects
Dermal Regeneration Template for Full-Thickness Scalp Defects: This review of a novel procedure for reconstruction of large skin defects on the scalp includes application of a bilayer wound matrix and delayed split-thickness skin grafting in a population of patients undergoing surgical resection of cutaneous lesions.
Electronic Data Repository for Patients With Nasal Obstruction
Electronic Data Repository for Patients With Nasal Obstruction: [image: s_qld150004f1.png] The data collection tool described herein contains a standardized nasal examination, operative details, and patient-reported outcomes measures for patients with nasal obstruction.
Erratum
(Source: Pediatric Blood and Cancer) from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/23iJ0FQ via IFTTT
It is Time to Let in Pediatric Palliative Care
(Source: Pediatric Blood and Cancer) from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/23iJ0pb via IFTTT
The Impact of Prehospital Intubation With and Without Sedation on Outcome in Trauma Patients With a GCS of 8 or Less.
Background: Although unconsciousness (Glasgow Coma Scale [GCS] 3 to 8) necessitates intubation according national guidelines, there is a notable lack of evidence to support this approach. This study evaluates the impact on outcome of prehospital intubation with and without sedation in trauma patients with a GCS of from #ORL-AlexandrosSfakianakis via simeraentaxei on Inoreader http://ift.tt/1nCIFgS via… Continue reading The Impact of Prehospital Intubation With and Without Sedation on Outcome in Trauma Patients With a GCS of 8 or Less.
Willingness to Pay for CT Colonography: A Survey of Patient Preferences
American Journal of Roentgenology, Volume 206, Issue 2, Page 355-358, February 2016. from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1PIxARK via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174 from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1SB1yxl via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis… Continue reading Willingness to Pay for CT Colonography: A Survey of Patient Preferences
Issue Information
(Source: Pediatric Blood and Cancer) from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1OKGFJZ via IFTTT
Tramadol-Paracetamol Combination for Postoperative Pain Relief in Elective Single-level Microdisectomy Surgery.
Background: The tramadol and paracetamol combination is used frequently for postoperative pain management. The literature on the use of this combination for vertebral surgery is limited. Our objective was to compare a combination of paracetamol 1 g and a lower dose of tramadol (1 mg/kg: group 1T) with a combination of paracetamol 1 g and… Continue reading Tramadol-Paracetamol Combination for Postoperative Pain Relief in Elective Single-level Microdisectomy Surgery.
Hydroxyurea use in Children with Sickle Cell Disease: Do Severely Affected Patients Use It and Does It Impact Hospitalization Outcomes?
ConclusionsHU use is high among hospitalized children with SCD. However, HU is not utilized by many children with clinically severe SCD. These results support that HU be considered in children with SCD to prevent hospitalization rather than as a treatment to improve hospitalization outcomes. (Source: Pediatric Blood and Cancer) from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader… Continue reading Hydroxyurea use in Children with Sickle Cell Disease: Do Severely Affected Patients Use It and Does It Impact Hospitalization Outcomes?
Classification and Algorithmic Management of Constricted Ears: A 22-Year Experience.
Background: The term ‘constricted ear’ was coined by Tanzer. The classification and corrective methods for these malformations, however, continue to be controversial. To clarify them, we have reviewed and analyzed cases operated at our Center from January 1992 to January 2014. Methods: A total of 164 ear cases (involving 139 patients), showing features of lidded… Continue reading Classification and Algorithmic Management of Constricted Ears: A 22-Year Experience.
An open-label, dose-escalation study to evaluate the safety and pharmacokinetics of CEP-9722 (a PARP-1 and PARP-2 inhibitor) in combination with gemcitabine and cisplatin in patients with advanced solid tumors.
Poly (ADP-ribose) polymerase-1 (PARP-1) inhibitors may potentiate chemotherapy by hindering DNA damage repair pathways. CEP-9722 is the prodrug of CEP-8983, a selective inhibitor of PARP-1 and PARP-2. Preclinical studies and a prior phase 1 study suggested that CEP-9722 may cause less myelosuppression than has been observed with other oral PARP inhibitors. The primary objective of… Continue reading An open-label, dose-escalation study to evaluate the safety and pharmacokinetics of CEP-9722 (a PARP-1 and PARP-2 inhibitor) in combination with gemcitabine and cisplatin in patients with... περισσότερα »
Safe and Sound (So Far): A Radiopharmaceutical for GI TumorsSafe and Sound (So Far): A Radiopharmaceutical for GI Tumors
An investigative treatment for midgut neuroendocrine tumors demonstrated some unprecedented efficacy results in early analyses. Now the safety data are a bit more mature. Medscape Medical News (Source: Medscape Hematology-Oncology Headlines) from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1Kug2HB via IFTTT
Early Nerve Grafting in Patients With Facial Paralysis
Early Nerve Grafting in Patients With Facial Paralysis: This study evaluated the use of the pattern of facial paralysis recovery in the early postoperative months as a sole predictor in selecting patients for facial nerve grafting after cerebellopontine angle tumor resection when cranial nerve VII is uninterrupted.
Fluid Fat Injection for the Periocular Aesthetic Unit
Fluid Fat Injection for the Periocular Aesthetic Unit: [image: s_qpe150006f1.png] This report of surgical cases describes the successful use of superficial enhanced fluid fat injection for rejuvenation of the periocular aesthetic unit.
Polydioxanone Absorbable Plate for Cartilaginous Grafting
Polydioxanone Absorbable Plate for Cartilaginous Grafting: This randomized clinical trial examines the use of a polydioxanone absorbable plate for stabilization and positioning of caudal septal extension grafts in a population of patients undergoing surgical nasal correction.
Including the Patient Voice in Aesthetic Rhinoplasty Outcomes
Including the Patient Voice in Aesthetic Rhinoplasty Outcomes: [image: qic150010.pdf.gif] In “Development and Psychometric Evaluation of the FACE-Q Scales for Patients Undergoing Rhinoplasty,” Klassen et al present an exciting new patient-reported outcome (PRO) tool specific to these patients and intended to assess the aesthetic components of the procedure. Patient-reported outcomes are the patients’ feedback, elicited directly from them without interpretation by the physician or others, on how they perceive the physical, mental, or social condition related to their condition or... περισσότερα »
Addressing Saddle Nose Deformity
Addressing Saddle Nose Deformity: [image: qle150004.pdf.gif] *To the Editor* Saddle nose deformity is one of the most complex cases that a rhinoplasty surgeon has to deal with. Surgery to address this deformity is tricky, with nasal airflow often being impaired in order to achieve a cosmetic improvement of the nose. When properly planned and executed, however, the outcome of surgery addressing saddle nose deformity can be quite rewarding for both the patient and the surgeon.
The FACE-Q Scales for Patients Undergoing Rhinoplasty
The FACE-Q Scales for Patients Undergoing Rhinoplasty: This survey study describes the development and psychometric evaluation of the FACE-Q scales and adverse effects checklist designed to measure rhinoplasty outcomes. *Importance* Rhinoplasty continues to rank among the most popular cosmetic surgical treatments. Measuring what the nose looks like has typically involved the use of observer-reported or physician-reported outcome measures (eg, photographs). While objective outcomes are important, facial appearance is subjective, and asking patients what they think about the appea...περισσότερα »
Facial Nerve
A Facial Nerve Anniversary: [image: qic150012.pdf.gif] One of the worst moments in the early lives of children occurs when they awake the morning after their birthday and realize that 364 days separate them from their next birthday. The seemingly endless, yearlong wait that faces the unhappy child the day after his or her birthday is exactly the same “treatment” that we recommend to many of our patients with facial paralysis. As treating physicians, we likely fail to fully appreciate the isolation, sadness, and subtle but innumerable reminders of facial disability that fill eac... περισσότερα »
Global Perspective of Beauty in a Multicultural World
Global Perspective of Beauty in a Multicultural World: [image: qvp150004.pdf.gif] This Viewpoint explains why it is important not to assume which culture the patient identifies with most and why it is imperative that a facial plastic surgeon understands a patient’s ethnic identity and aesthetic goals prior to any procedure.
Periorbital and Midfacial Volume Enhancement With Cannula
Periorbital and Midfacial Volume Enhancement With Cannula: [image: s_qpe150007f1.png] This surgical technique video illustrates how to create attractive results in periorbital and midfacial filling.
Long term comparison of rib and ear cartilage grafts in autologous and allogenic fascia lata - an experimental study in a white rabbit model.
Long term comparison of rib and ear cartilage grafts in autologous and allogenic fascia lata - an experimental study in a white rabbit model.: Background: Diced cartilage in fascia grafts (DCF) have become the material of choice for dorsal grafts in rhinoplasty. Allogenic fascia lata has not yet been investigated as isolated fascial graft or as a combined graft with ear and rib cartilage, especially in comparison to autologous fascia and over a long implantation period. Methods: 10 different grafts were built from either autologous or allogenic fascia lata alone or as DCFs with diced... περισσότερα »
3D Topographical Surface Changes in Response to Compartmental Volumization of the Medial Cheek; Defining a Malar "Augmentation Zone".
3D Topographical Surface Changes in Response to Compartmental Volumization of the Medial Cheek; Defining a Malar "Augmentation Zone".: Background: Given the widespread use of facial fillers and recent identification of distinct facial fat compartments, a better understanding of 3D surface changes in response to volume augmentation is needed. Advances in 3D imaging technology now afford an opportunity to elucidate these morphological changes for the first time. Methods: A cadaver study was undertaken in which volumization of the deep medial cheek (DMC) compartment was performed at int...περισσότερα »
Classification and Algorithmic Management of Constricted Ears: A 22-Year Experience.
Classification and Algorithmic Management of Constricted Ears: A 22-Year Experience.: Background: The term 'constricted ear' was coined by Tanzer. The classification and corrective methods for these malformations, however, continue to be controversial. To clarify them, we have reviewed and analyzed cases operated at our Center from January 1992 to January 2014. Methods: A total of 164 ear cases (involving 139 patients), showing features of lidded helix, compression of scapha and fossa triangularis, and/or cup-like protrusions were included in our study (constricted ear-featured micro... περισσότερα »
Blocked nose (82.7%), rhinorrhea (75.0%), sneeze (70.9%), itchy nose (68.5%), fatigue (63.6%), mouth breathing (61.1%), daytime somnolence (52.7%), postnasal drip (49.1%), itchy eyes (47.3%), and dry mouth (46.3%).
Extranasal symptoms of allergic rhinitis are difficult to treat and affect quality of life via Allergology International Publication date: Available online 19 January 2016 *Source:*Allergology International Author(s): Veeravich Jaruvongvanich, Pungjai Mongkolpathumrat, Hiroshi Chantaphakul, Jettanong Klaewsongkram BackgroundTotal nasal symptom score is widely used to evaluate the severity of allergic rhinitis, but the clinical significance of extranasal symptoms is largely unknown. We wished to analyze the presenting symptoms in allergic rhinitis, as well as their relationship with qua... περισσότερα »
Food allergy is modulated through the thymic stromal lymphopoietin pathway
Food allergy in mice is modulated through the thymic stromal lymphopoietin pathway: Background: Thymic stromal lymphopoietin (TSLP) is involved in the pathogenesis of allergic reactions in the skin and the lung. Nevertheless, data on the role of TSLP in food allergy are scarce. We explored the role of TSLP in a mouse model with oral sensitization and oral challenge eliciting food allergy. Methods: TSLP receptor (TSLPR)−/− mice and wild type mice were orally sensitized to β-lactoglobulin in presence of cholera toxin (CT) or CT alone. The elicited immune response was characterized in vi...περισσότερα »
Tolerance of a high-protein baked-egg product in egg-allergic children
Tolerance of a high-protein baked-egg product in egg-allergic children via ScienceDirect Publication: Annals of Allergy, Asthma & Immunology Publication date: Available online 20 January 2016 *Source:*Annals of Allergy, Asthma & Immunology Author(s): Maryam Saifi, Nithya Swamy, Maria Crain, L. Steven Brown, John Andrew Bird BackgroundEgg allergy is one of the most common immunoglobulin E (IgE)–mediated food allergies. Extensively heating egg has been found to decrease its allergenicity and 55% to 84% of children allergic to egg have been found to tolerate baked-egg products. Because the... περισσότερα »
Activation of Toll-like receptor signaling in bronchial epithelial cells triggered by Mycobacterial infections
A species-specific activation of Toll-like receptor signaling in bovine and sheep bronchial epithelial cells triggered by Mycobacterial infections via ScienceDirect Publication: Molecular Immunology Publication date: March 2016 *Source:*Molecular Immunology, Volume 71 Author(s): Yan Ma, Fei Han, Jinping Liang, Jiali Yang, Juan Shi, Jing Xue, Li Yang, Yong Li, Meihui Luo, Yujiong Wang, Jun Wei, Xiaoming Liu Pulmonary tuberculosis caused by a Mycobacterium infection remains a major public health problem in most part of the world, in part owing to the transmission of its pathogens between ... περισσότερα »
Issue Information
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 9 δευτερόλεπτα
(Source: Pediatric Blood and Cancer) from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1OKGFJZ via IFTTT
Anaphylaxis to the amoxicillin skin prick test
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 9 δευτερόλεπτα
Anaphylaxis to the amoxicillin skin prick test: utility of the basophil activation test in diagnosis: Anaphylaxis in response to a skin prick test (SPT) with the culprit drug rarely occurs in patients with a suspected drug allergy.1 The diagnosis of β-lactam hypersensitivity is usually based on the patient’s clinical history, positive skin test results, or […]
Hydroxyurea use in Children with Sickle Cell Disease: Do Severely Affected Patients Use It and Does It Impact Hospitalization Outcomes?
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 9 δευτερόλεπτα
ConclusionsHU use is high among hospitalized children with SCD. However, HU is not utilized by many children with clinically severe SCD. These results support that HU be considered in children with SCD to prevent hospitalization rather than as a treatment to improve hospitalization outcomes. (Source: Pediatric Blood and Cancer) from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader […]
Trypanosoma brucei rhodesiense sleeping sickness
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 9 δευτερόλεπτα
The role of cytokines in the pathogenesis and staging of Trypanosoma brucei rhodesiense sleeping sickness: Human African trypanosomiasis due to Trypanosoma brucei rhodesiense is invariably fatal if untreated with up to 12.3 million people at a risk of developing the disease in Sub-Saharan Africa. The disease is characterized by a wide spectrum of clinical presentation […]
Safe and Sound (So Far): A Radiopharmaceutical for GI TumorsSafe and Sound (So Far): A Radiopharmaceutical for GI Tumors
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 9 δευτερόλεπτα
An investigative treatment for midgut neuroendocrine tumors demonstrated some unprecedented efficacy results in early analyses. Now the safety data are a bit more mature. Medscape Medical News (Source: Medscape Hematology-Oncology Headlines) from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1Kug2HB via IFTTT
Porous Organic Cage Thin Films and Molecular-Sieving Membranes
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 9 δευτερόλεπτα
Porous organic cage molecules are fabricated into thin films and molecular-sieving membranes. Cage molecules are solution cast on various substrates to form amorphous thin films, with the structures tuned by tailoring the cage chemistry and processing conditions. For the first time, uniform and pinhole-free microporous cage thin films are formed and demonstrated as molecular-sieving membranes […]
Early Admission to Hospice Key to Good End-of-Life CareEarly Admission to Hospice Key to Good End-of-Life Care
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 9 δευτερόλεπτα
Early admission to hospice, no ICU admissions in the days before death, and not dying in hospital are perceived as good end-of-life care among family members who have lost their loved ones to cancer. Medscape Medical News (Source: Medscape Hematology-Oncology Headlines) from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1Kug2au via IFTTT
Adaptive self-organizing organisms using a bio-inspired gene regulatory network controller: for the aggregation of evolutionary robots under a changing environment
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 9 δευτερόλεπτα
This work has explored the adaptive potential of simulated swarm robots that contain a genomic encoding of a bio-inspired gene regulatory network (GRN). An artificial genome is combined with a flexible agent-based system, representing the activated part of the regulatory network that transduces environmental cues into phenotypic behavior. Using an Alife simulation framework that mimics […]
Saccharification protocol for small-scale lignocellulosic biomass samples to test processing of cellulose into glucose
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 9 δευτερόλεπτα
Second generation biofuels are derived from inedible lignocellulosic biomass of food and non-food crops. Lignocellulosic biomass is mainly composed of cell walls that contain a large proportion of cellulosic and hemicellulosic polysaccharides. An interesting route to generate biofuels and bio-based materials is via enzymatic hydrolysis of cell wall polysaccharides into fermentable sugars, a process called […]
Childhood Cancer Survivors Forgo Care Because of CostChildhood Cancer Survivors Forgo Care Because of Cost
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 9 δευτερόλεπτα
Many survivors of childhood cancer are not getting needed care because of cost, and those particularly at risk tend to be uninsured, female, and have a chronic medical condition. Medscape Medical News (Source: Medscape Hematology-Oncology Headlines) from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1Tc9p3R via IFTTT
The immunogenetic predisposition to antiphospholipid syndrome (APS)
Genetic aspects of the antiphospholipid syndrome: An update via Autoimmunity Reviews Publication date: Available online 21 January 2016 *Source:*Autoimmunity Reviews Author(s): Gian Domenico Sebastiani, Annamaria Iuliano, Luca Cantarini, Mauro Galeazzi Studies on the immunogenetic predisposition to antiphospholipid syndrome (APS) and on other non genetic and epigenetic factors are summarised and discussed. Family studies suggest a genetic predisposition to APS. It appears that this genetic predisposition is in part accounted for by the HLA system, the most consistent associations being...περισσότερα »
The Mastocytosis Quality of Life questionnaire: MC-QoL
Development and Validation of the Mastocytosis Quality of Life questionnaire: MC-QoL: [image: cover.gif?v=1&s=e49413b3a608982cc9a6b00f] Abstract Background Mastocytosis is a heterogeneous disease characterized by a clonal expansion of mast cells in various organs. The vast majority of patients affected suffer from signs and symptoms caused by mediator release from mast cells. Although the disease burden is high, there is currently no specific instrument to measure health-related quality of life (HRQoL) impairment in patients with mastocytosis. Objective To develop and validate a... περισσότερα »
Clinical features predict responsiveness to imatinib in platelet derived growth factor receptor alpha-negative hypereosinophilic syndrome
Clinical features predict responsiveness to imatinib in platelet derived growth factor receptor alpha-negative hypereosinophilic syndrome: [image: cover.gif?v=1&s=e49413b3a608982cc9a6b00f] Summary With the exception of the presence of the *FIP1L1-PDGFRA* fusion gene, little is known about predictors of imatinib response in clinically-defined hypereosinophilic syndrome (HES). Subjects with *FIP1L1-PDGFRA*-myeloid neoplasm (FP; n=12), *PDGFRA*-negative HES with ≥4 criteria suggestive of a myeloid neoplasm (MHES; n=10), or steroid-refractory *PDGFRA-*negative HES with <4 myeloid cr... περισσότερα »
Atopic dermatitis phenotype with early onset and high serum IL-13 is linked to the new development of bronchial hyperresponsiveness in school children
Atopic dermatitis phenotype with early onset and high serum IL-13 is linked to the new development of bronchial hyperresponsiveness in school children: [image: cover.gif?v=1&s=e49413b3a608982cc9a6b00f] Abstract Background Atopic dermatitis (AD) is characterized by a heterogeneous clinical spectrum, and some forms of AD are associated with the initial steps of allergic march. The aims of this study were to determine AD phenotypes in school-age children and investigate their associations with the allergic march in each cluster. Methods We included 242 children (6–8 years) with curr... περισσότερα »
What proportion of adult allergy referrals to secondary care could be dealt with in primary care by a GP with special interest?
What proportion of adult allergy referrals to secondary care could be dealt with in primary care by a GP with special interest?: Background: The concept of a General Practitioner with Special Interest (GPwSI) was first proposed in the 2000 National Health Service Plan, as a way of providing specialised treatment closer to the patient’s home and reducing hospital waiting times. Given the patchy and inadequate provision of allergy services in the UK the introduction of GPwSIs might reduce the pressure on existing specialist services.ObjectivesThis study assessed what proportion of refe... περισσότερα »
Local reaction of the nasal mucosa to an environmental factor
, the allergen via Alergologia Polska - Polish Journal of Allergology Publication date: Available online 21 January 2016 *Source:*Alergologia Polska - Polish Journal of Allergology Author(s): Edyta Krzych-Fałta, Adam J. Sybilski, Bolesław Samoliński The Purpose of the study was to assess the inflammatory response of the nasal mucosa based on nitric oxide concentration in exhaled breath and the level of inflammatory markers tryptase/eosinophil cation protein (ECP) in the nasal lavage fluid obtained via a nasal lavage collection device of our design. Material: The study group included 60 ...περισσότερα »
Nasal and ocular responses after specific and nonspecific nasal challenges in seasonal allergic rhinitis
Nasal and ocular responses after specific and nonspecific nasal challenges in seasonal allergic rhinitis via ScienceDirect Publication: Annals of Allergy, Asthma & Immunology Publication date: Available online 21 January 2016 *Source:*Annals of Allergy, Asthma & Immunology Author(s): Dejan Tomljenovic, Tomislav Baudoin, Zeljka Bukovec Megla, Davor Vagic, Peter Hellings, Livije Kalogjera BackgroundDifferent nasal challenges induce neural and immune response leading to nasal and ocular symptoms in patients with seasonal allergic rhinitis (SAR). The release of neural mediators from nasal m... περισσότερα »
Prevalence and clinical correlation of serum immunoglobulin E in patients with chronic spontaneous urticaria
Prevalence and clinical correlation of serum immunoglobulin E in patients with chronic spontaneous urticaria: Immunoglobulin (Ig) G plays a major role in the pathogenesis of autoantibodies by identifying IgG antibodies against IgE or IgG antibodies directed to the α subunit of the high-affinity IgE receptor. Recent studies have reported that omalizumab (a monoclonal anti-IgE antibody) is very effective in the treatment of refractory chronic spontaneous urticaria (CSU).1,2 However, the association between serum IgE level and disease severity of CSU is inconclusive. This retrospective...περισσότερα »
Vitamin D levels and incidence of food-induced anaphylaxis
Regional differences in vitamin D levels and incidence of food-induced anaphylaxis in South Korea: Previous studies have suggested low vitamin D as a potential risk factor for food allergy/anaphylaxis. However, few studies have investigated the association between vitamin D and food-induced anaphylaxis (FIA) in South Korea.
Effectiveness of omalizumab in severe solar urticaria
Effectiveness of omalizumab in severe solar urticaria: Solar urticaria (SU) is an uncommon, chronic, and disabling photodermatosis included in the group of physical urticarias. Wheals accompanied with pruritus or burning sensation appear after a few minutes on sun-exposed skin, disappearing after 1 to 2 hours. In severe cases, if sun exposure is intense, a more extended reaction can lead to systemic symptoms and anaphylaxis.1 The eliciting wavelengths (action spectra) vary from one individual to another but commonly involve UV-A, alone or with UV-B or visible light (VL).
Nasal and ocular responses after specific and nonspecific nasal challenges in seasonal allergic rhinitis
Nasal and ocular responses after specific and nonspecific nasal challenges in seasonal allergic rhinitis: Different nasal challenges induce neural and immune response leading to nasal and ocular symptoms in patients with seasonal allergic rhinitis (SAR). The release of neural mediators from nasal mucosa and conjunctiva after no-specific challenges in patients with SAR remains unknown.
The basophil activation test
Anaphylaxis to the amoxicillin skin prick test: utility of the basophil activation test in diagnosis: Anaphylaxis in response to a skin prick test (SPT) with the culprit drug rarely occurs in patients with a suspected drug allergy.1 The diagnosis of β-lactam hypersensitivity is usually based on the patient's clinical history, positive skin test results, or specific IgE antibody measurements. The basophil activation test (BAT) should be performed in cases in which the diagnosis of a drug allergy is highly suspected but is not supported by the results of skin testing or in vitro IgE m... περισσότερα »
Anaphylaxis to the amoxicillin skin prick test
Anaphylaxis to the amoxicillin skin prick test: utility of the basophil activation test in diagnosis: Anaphylaxis in response to a skin prick test (SPT) with the culprit drug rarely occurs in patients with a suspected drug allergy.1 The diagnosis of β-lactam hypersensitivity is usually based on the patient's clinical history, positive skin test results, or specific IgE antibody measurements. The basophil activation test (BAT) should be performed in cases in which the diagnosis of a drug allergy is highly suspected but is not supported by the results of skin testing or in vitro IgE m... περισσότερα »
Trypanosoma brucei rhodesiense sleeping sickness
The role of cytokines in the pathogenesis and staging of Trypanosoma brucei rhodesiense sleeping sickness: [image: sfx_links?getImage] Human African trypanosomiasis due to Trypanosoma brucei rhodesiense is invariably fatal if untreated with up to 12.3 million people at a risk of developing the disease in Sub-Saharan Africa. The disease is characterized by a wide spectrum of clinical presentation coupled with differences in disease progression and severity. While the factors determining this varied response have not been clearly characterized, inflammatory cytokines have been parti...περισσότερα »
Association between allergic rhinitis and metabolic conditions
Association between allergic rhinitis and metabolic conditions: a nationwide survey in Korea: Background: Accumulating evidence indicates a strong correlation between allergic disease and cardiovascular risks. In spite of this, the data concerning the association between allergic rhinitis (AR) and cardiovascular risks is sparse and conflicting. This study aimed to investigate the association between AR prevalence and metabolic syndrome (MetS) in a large-scale, population-based survey, while considering the relevant risk factors. Methods: A nationwide cross-sectional study was conducte...περισσότερα »
Cluster analysis and prediction of treatment outcomes for chronic rhinosinusitis
Cluster analysis and prediction of treatment outcomes for chronic rhinosinusitis via Allergy and Clinical Immunology Publication date: Available online 22 January 2016 *Source:*Journal of Allergy and Clinical Immunology Author(s): Zachary M. Soler, J. Madison Hyer, Luke Rudmik, Viswanathan Ramakrishnan, Timothy L. Smith, Rodney J. Schlosser BackgroundCurrent clinical classifications of chronic rhinosinusitis (CRS) have weak prognostic utility regarding treatment outcomes. Simplified discriminant analysis based on unsupervised clustering has identified novel phenotypic subgroups of CRS,... περισσότερα »
Anaphylaxis following a transvaginal ultrasound
Anaphylaxis following a transvaginal ultrasound: [image: s13223-015-0106-9-1.gif] Polyethylene glycol is a ubiquitous, water-soluble, organic compound found in a wide variety of commercially available products. While generally a benign substance, in rare instances, it can induce hypersensitivity reactions. Herein, we describe a case of anaphylaxis to polyethylene glycol-containing lubricating gel used for a transvaginal ultrasound. This case highlights the importance of early recognition of a rare cause of anaphylaxis that may occur in the health-care setting. It is of particula... περισσότερα »
The European Anaphylaxis Registry
Anaphylaxis in children and adolescents: The European Anaphylaxis Registry via Allergy and Clinical Immunology Publication date: Available online 21 January 2016 *Source:*Journal of Allergy and Clinical Immunology Author(s): Linus B. Grabenhenrich, Sabine Dölle, Anne Moneret-Vautrin, Alice Köhli, Lars Lange, Thomas Spindler, Franziska Ruëff, Katja Nemat, Ioana Maris, Eirini Roumpedaki, Kathrin Scherer, Hagen Ott, Thomas Reese, Tihomir Mustakov, Roland Lang, Montserrat Fernandez-Rivas, Marek L. Kowalski, Maria B. Bilò, Jonathan O'B. Hourihane, Nikolaos G. Papadopoulos, Kirsten Beyer, An... περισσότερα »
Eosinophilic esophagitis is characterized by a non-IgE-mediated food hypersensitivity
Eosinophilic esophagitis is characterized by a non-IgE-mediated food hypersensitivity: Abstract Eosinophilic esophagitis (EoE) is a chronic disease characterized clinically by symptoms of esophageal dysfunction and histologically by eosinophil-predominant inflammation. EoE is frequently associated with concomitant atopic diseases and immunoglobulin E (IgE) sensitization to food allergens in children as well as to aeroallergens and cross-reactive plant allergen components in adults. Patients with EoE respond well to elemental and empirical food elimination diets. Recent research has... περισσότερα »
Subglottic mass
Adenoid cystic carcinoma of the larynx presenting with unusual subglottic mass: Case report via Auris Nasus Larynx Publication date: Available online 21 January 2016 *Source:*Auris Nasus Larynx Author(s): Takashi Kashiwagi, Hiroaki Kanaya, Wataru Konno, Kazutaka Goto, Hideki Hirabayashi, Shin-ichi Haruna A 33-year-old woman presented with an unusual subglottic bulging mass accompanied by prolonged cough and wheeze. Laryngeal endoscopy revealed a bilateral, symmetrical mass immediately below the vocal cords with marked airway obstruction. Chronic subglottic laryngitis with inflammation ... περισσότερα »
Safety of heat generated by endoscope light sources
Safety of heat generated by endoscope light sources in simulated transcanal endoscopic ear surgery via Auris Nasus Larynx Publication date: Available online 21 January 2016 *Source:*Auris Nasus Larynx Author(s): Tsukasa Ito, Toshinori Kubota, Akira Takagi, Tomoo Watanabe, Kazunori Futai, Takatoshi Furukawa, Seiji Kakehata ObjectiveTo determine whether heat generated by endoscope light sources during ear surgery is safe.MethodsTranscanal endoscopic ear surgery (TEES) was simulated using 2.7-mm or 4-mm endoscopes coupled to xenon or LED light sources and a 3D model of human temporal bone... περισσότερα »
OnabotulinumtoxinA 195 U in medication overuse headache
A two years open-label prospective study of OnabotulinumtoxinA 195 U in medication overuse headache: a real-world experience: Background: The efficacy and safety of OnabotulinumtoxinA (BOTOX®) in adults with chronic migraine (CM) were demonstrated in the PREEMPT program. However, the dosage used in this study was flexible from 155 U to 195 U at the physician’s discretion. Therefore, the objective of this prospective study was to compare the efficacy and safety of OnabotulinumtoxinA 195 U vs. 155 U for the treatment of CM and medication overuse headache (MOH) during a 2-year period. M... περισσότερα »
Pitch and spectral resolution: A systematic comparison of bottom-up cues for top-down repair of degraded speecha)
Pitch and spectral resolution: A systematic comparison of bottom-up cues for top-down repair of degraded speecha): The brain is capable of restoring missing parts of speech, a top-down repair mechanism that enhances speech understanding in noisy environments. This enhancement can be quantified using the phonemic restoration paradigm, i.e., the improvement in intelligibility when silent interruptions of interrupted speech are filled with noise. Benefit from top-down repair of speech differs between cochlear implant(CI) users and normal-hearing (NH) listeners. This difference could b... περισσότερα »
Temporal weighting of loudness: Comparison between two different psychophysical tasks
Temporal weighting of loudness: Comparison between two different psychophysical tasks: Psychophysical studies on loudness have so far examined the temporal weighting of loudness solely in level-discrimination tasks. Typically, listeners were asked to discriminate hundreds of level-fluctuating sounds regarding their global loudness. Temporal weights, i.e., the importance of each temporal portion of the stimuli for the loudness judgment, were then estimated from listeners' responses. Consistent non-uniform “u-shaped” temporal weighting patterns were observed, with greater weights ass... περισσότερα »
Performance metrics for depth-based signal separation using deep vertical line arrays
Performance metrics for depth-based signal separation using deep vertical line arrays: A recent publication by McCargar and Zurk [(2013). J. Acoust. Soc. Am. 133(4), EL320–EL325] introduced a modified Fourier transform-based method for passive source depth estimation using vertical line arrays deployed below the critical depth in the deep ocean. This method utilizes the depth-dependent modulation caused by the interference between the direct and surface-reflected acoustic arrivals, the observation of which is enhanced by propagation through the reliable acoustic path. However, nei... περισσότερα »
Relationship between tongue positions and formant frequencies in female speakers
Relationship between tongue positions and formant frequencies in female speakers: This study examined the relationship (1) between acoustic vowel space and the corresponding tongue kinematicvowel space and (2) between formant frequencies (F1 and F2) and tongue x-y coordinates for the same time sampling point. Thirteen healthy female adults participated in this study. Electromagnetic articulography and synchronized acoustic recordings were utilized to obtain vowel acoustic and tongue kinematic data across ten speech tasks. Intra-speaker analyses showed that for 10 of the 13 speakers...περισσότερα »
Effects of Different Insertion Techniques of a Cochlear Implant Electrode on the Intracochlear Pressure
Effects of Different Insertion Techniques of a Cochlear Implant Electrode on the Intracochlear Pressure: To achieve a functional atraumatic insertion, low intracochlear pressure changes during the procedure are assumed to be important. The aim of this study was to observe intracochlear pressure changes due to different insertion techniques in a cochlear model. Cochlear implant electrode insertions were performed in an artificial cochlear model to record intracochlear pressure changes with a micropressure sensor to evaluate the maximum amplitude and frequency of pressure changes unde...περισσότερα »
Do Live Versus Audio-Recorded Narrative Stimuli Influence Young Children's Narrative Comprehension and Retell Quality?
Do Live Versus Audio-Recorded Narrative Stimuli Influence Young Children's Narrative Comprehension and Retell Quality?: Purpose The primary aim of the present study was to examine whether different ways of presenting narrative stimuli (i.e., live narrative stimuli versus audio-recorded narrative stimuli) influence children's performances on narrative comprehension and oral-retell quality. Method Children in kindergarten (n = 54), second grade (n = 74), and fourth grade ( n = 65) were matched on their performance on a standardized oral-language comprehension task and then were rando... περισσότερα »
Cosmetic preservative labelling on the Thai market
Summary Background Preservatives are added to cosmetics and other consumer products to prevent microbial growth and product degradation. Many cosmetic preservatives are skin sensitizers and frequent causes of contact dermatitis. The use of preservatives may vary by country and/or region, according to legislation, and may be reflected in differences in the prevalence rates of preservative allergy worldwide. Objective To examine the type and frequency of preservative use in cosmetics sold in Thai markets in metropolitan Bangkok, Thailand. Methods Preservatives contained in 1000 d...περισσότερα »
Classification and Algorithmic Management of Constricted Ears: A 22-Year Experience.
Background: The term 'constricted ear' was coined by Tanzer. The classification and corrective methods for these malformations, however, continue to be controversial. To clarify them, we have reviewed and analyzed cases operated at our Center from January 1992 to January 2014. Methods: A total of 164 ear cases (involving 139 patients), showing features of lidded helix, compression of scapha and fossa triangularis, and/or cup-like protrusions were included in our study (constricted ear-featured microtias were excluded) and reviewed through medical records, photographs, analysis of su...περισσότερα »
Primary versus Flap Closure of Perineal Defects Following Oncologic Resection: A Systematic Review and Meta Analysis.
No abstract available from #Aesthetics via alexandrossfakianakis on Inoreader http://ift.tt/1S8SluB via IFTTT
3D Topographical Surface Changes in Response to Compartmental Volumization of the Medial Cheek; Defining a Malar "Augmentation Zone".
Background: Given the widespread use of facial fillers and recent identification of distinct facial fat compartments, a better understanding of 3D surface changes in response to volume augmentation is needed. Advances in 3D imaging technology now afford an opportunity to elucidate these morphological changes for the first time. Methods: A cadaver study was undertaken in which volumization of the deep medial cheek (DMC) compartment was performed at intervals up to 4cc (n=4). 3D photographs were taken following each injection in order to analyze the topographical surface changes which...περισσότερα »
Long term comparison of rib and ear cartilage grafts in autologous and allogenic fascia lata - an experimental study in a white rabbit model.
Background: Diced cartilage in fascia grafts (DCF) have become the material of choice for dorsal grafts in rhinoplasty. Allogenic fascia lata has not yet been investigated as isolated fascial graft or as a combined graft with ear and rib cartilage, especially in comparison to autologous fascia and over a long implantation period. Methods: 10 different grafts were built from either autologous or allogenic fascia lata alone or as DCFs with diced costal or ear cartilage and implanted into the dorsal skin of 15 rabbits. After 3 or 9 months the grafts were explanted and histologically ana... περισσότερα »
Long-term follow-up of quality of life following DIEP flap breast reconstruction.
Background: Sequelae due to breast cancer are very high and negatively impact patient quality of life (QoL). Although deep inferior epigastric perforator (DIEP) flap has become a standard for autologous breast reconstruction (BR), there are limited data regarding long-term QoL. This study aimed to measure patient QoL more than 5 years after DIEP flap BR and compare the finding with two French reference samples. Methods: A cross-sectionnal study of QoL was performed in women who underwent DIEP flap BR between 1995 and 2007 using the Medical Outcomes Study 36-item short-form health su...περισσότερα »
Three-dimensional computed tomographic angiographic study of the inter-perforator flow of the lower leg.
Background: The area perfused by a single perforator depends on its perforasome and its unique inter-perforator flow pattern. The purpose of this study was to clarify the inter-perforator flow patterns of the peroneal and posterior tibial artery perforators (PA-Ps, PTA-Ps) using three-dimensional computed tomographic angiography (3D-CTA). Methods: Thirteen whole leg skin flaps were harvested in the subfacial plane from fresh cadavers. PA-Ps, PTA-Ps, anterior tibial, and sural artery perforators (ATA-Ps, SA-Ps) with a diameter greater than 0.5 mm were documented. 3D-CTA with an injec... περισσότερα »
Defining quality in healthcare and measuring quality in Surgery.
Quality in healthcare has been sluggish to adapt to the changing landscape, leading to lapses in the successful delivery of care. Consequently, quality of care has come under intense scrutiny in the past decade resulting in the creation of various federally-funded and non-profit org anizations aimed at assessing and implementing systematic quality improvements. In this article, we examine the evolution of quality in healthcare relative to established quality control measures in other sectors, different ways to assess quality, and the current state of our healthcare system. (C)2016Am... περισσότερα »
Comments on "A Cadaveric Study Comparing the Efficacy of the Sheen Spreader Graft and the Fulcrum Spreader Graft".
No abstract available from #Aesthetics via alexandrossfakianakis on Inoreader http://ift.tt/1NoKRgF via IFTTT
Reducing abdominal seroma after DIEP flap breast reconstruction, outcomes in 726 patients.
No abstract available from #Aesthetics via alexandrossfakianakis on Inoreader http://ift.tt/1S8SgqW via IFTTT
RE: TUGs into VUGs and Friendly BUGs: Transforming the Gracilis Territory into the Best Secondary Breast Reconstructive Option.
No abstract available from #Aesthetics via alexandrossfakianakis on Inoreader http://ift.tt/1NoKQJD via IFTTT
Reply: Reducing abdominal seroma after DIEP flap breast reconstruction, outcomes in 726 patients.
No abstract available from #Aesthetics via alexandrossfakianakis on Inoreader http://ift.tt/1S8SiyQ via IFTTT
Response to Cragg et al. Letter to the Editor.
No abstract available from #Aesthetics via alexandrossfakianakis on Inoreader http://ift.tt/1S8Sgad via IFTTT
How rheumatoid arthritis patients make decisions regarding hand reconstruction: A qualitative study from the SARA Project.
Background: Previous studies have determined specific factors influencing patients with rheumatoid arthritis (RA) to choose to undergo reconstructive hand surgery. However, little is known about how RA patients are counseled by physicians regarding surgical options and the concerns that cause patients to decide not to have hand surgery reconstruction. We conducted a qualitative study to investigate the decision-making process RA patients undergo when deciding about surgical treatment, including the specific involvement from their physicians in the decision. Methods: Participants wer... περισσότερα »
Effects of auditory enhancement on the loudness of masker and target components
Publication date: Available online 22 January 2016 *Source:*Hearing Research Author(s): Ningyuan Wang, Andrew J. Oxenham Auditory enhancement refers to the observation that the salience of one spectral region (the “signal”) of a broadband sound can be enhanced and can “pop out” from the remainder of the sound (the “masker”) if it is preceded by the broadband sound without the signal. The present study investigated auditory enhancement as an effective change in loudness, to determine whether it reflects a change in the loudness of the signal, the masker, or both. In the first experimen... περισσότερα »
Effects of auditory enhancement on the loudness of masker and target components
Publication date: Available online 22 January 2016 *Source:*Hearing Research Author(s): Ningyuan Wang, Andrew J. Oxenham Auditory enhancement refers to the observation that the salience of one spectral region (the “signal”) of a broadband sound can be enhanced and can “pop out” from the remainder of the sound (the “masker”) if it is preceded by the broadband sound without the signal. The present study investigated auditory enhancement as an effective change in loudness, to determine whether it reflects a change in the loudness of the signal, the masker, or both. In the first experimen... περισσότερα »
Effects of auditory enhancement on the loudness of masker and target components
Publication date: Available online 22 January 2016 *Source:*Hearing Research Author(s): Ningyuan Wang, Andrew J. Oxenham Auditory enhancement refers to the observation that the salience of one spectral region (the “signal”) of a broadband sound can be enhanced and can “pop out” from the remainder of the sound (the “masker”) if it is preceded by the broadband sound without the signal. The present study investigated auditory enhancement as an effective change in loudness, to determine whether it reflects a change in the loudness of the signal, the masker, or both. In the first experimen... περισσότερα »
In-shoe plantar pressure measurements for the evaluation and adaptation of foot orthoses in patients with rheumatoid arthritis: A proof of concept study
Publication date: March 2016 *Source:*Gait & Posture, Volume 45 Author(s): Marloes Tenten-Diepenmaat, Joost Dekker, Menno Steenbergen, Elleke Huybrechts, Leo D. Roorda, Dirkjan van Schaardenburg, Sicco A. Bus, Marike van der Leeden ObjectivesImproving foot orthoses (FOs) in patients with rheumatoid arthritis (RA) by using in-shoe plantar pressure measurements seems promising. The objectives of this study were to evaluate (1) the outcome on plantar pressure distribution of FOs that were adapted using in-shoe plantar pressure measurements according to a protocol and (2) the protocol fe... περισσότερα »
Effects of auditory enhancement on the loudness of masker and target components
Publication date: Available online 22 January 2016 *Source:*Hearing Research Author(s): Ningyuan Wang, Andrew J. Oxenham Auditory enhancement refers to the observation that the salience of one spectral region (the “signal”) of a broadband sound can be enhanced and can “pop out” from the remainder of the sound (the “masker”) if it is preceded by the broadband sound without the signal. The present study investigated auditory enhancement as an effective change in loudness, to determine whether it reflects a change in the loudness of the signal, the masker, or both. In the first experimen... περισσότερα »
In-shoe plantar pressure measurements for the evaluation and adaptation of foot orthoses in patients with rheumatoid arthritis: A proof of concept study
Publication date: March 2016 *Source:*Gait & Posture, Volume 45 Author(s): Marloes Tenten-Diepenmaat, Joost Dekker, Menno Steenbergen, Elleke Huybrechts, Leo D. Roorda, Dirkjan van Schaardenburg, Sicco A. Bus, Marike van der Leeden ObjectivesImproving foot orthoses (FOs) in patients with rheumatoid arthritis (RA) by using in-shoe plantar pressure measurements seems promising. The objectives of this study were to evaluate (1) the outcome on plantar pressure distribution of FOs that were adapted using in-shoe plantar pressure measurements according to a protocol and (2) the protocol fe... περισσότερα »
Effects of auditory enhancement on the loudness of masker and target components
Publication date: Available online 22 January 2016 *Source:*Hearing Research Author(s): Ningyuan Wang, Andrew J. Oxenham Auditory enhancement refers to the observation that the salience of one spectral region (the “signal”) of a broadband sound can be enhanced and can “pop out” from the remainder of the sound (the “masker”) if it is preceded by the broadband sound without the signal. The present study investigated auditory enhancement as an effective change in loudness, to determine whether it reflects a change in the loudness of the signal, the masker, or both. In the first experimen... περισσότερα »
In-shoe plantar pressure measurements for the evaluation and adaptation of foot orthoses in patients with rheumatoid arthritis: A proof of concept study
Publication date: March 2016 *Source:*Gait & Posture, Volume 45 Author(s): Marloes Tenten-Diepenmaat, Joost Dekker, Menno Steenbergen, Elleke Huybrechts, Leo D. Roorda, Dirkjan van Schaardenburg, Sicco A. Bus, Marike van der Leeden ObjectivesImproving foot orthoses (FOs) in patients with rheumatoid arthritis (RA) by using in-shoe plantar pressure measurements seems promising. The objectives of this study were to evaluate (1) the outcome on plantar pressure distribution of FOs that were adapted using in-shoe plantar pressure measurements according to a protocol and (2) the protocol fe... περισσότερα »
Control of HIV-1 replication in vitro by vaccine-induced human CD8(+) T cells through conserved subdominant Pol epitopes.
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 37 δευτερόλεπτα
CONCLUSIONS: These results implicate the use of functionally conserved regions of Pol in addition to the widely used Gag for T-cell vaccine design. Proportion of volunteers developing these effectors and their frequency in circulation are separate issues, which can be addressed, if needed, by more efficient vector and regimen delivery of conserved immunogens. PMID: 26784683 […]
Multiplex immunoassay for in vitro characterization of acellular pertussis antigens in combination vaccines.
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 37 δευτερόλεπτα
Authors: Agnolon V, Bruno C, Galletti B, Mori E, Ugozzoli M, Pergola C, O’Hagan DT, Baudner BC Abstract Vaccines characterization is required to ensure physical, chemical, and biological integrity of antigens and adjuvants. Current analytical methods mostly require complete antigen desorption from aluminum-based adjuvants and are not always suitable to distinguish individual antigens in multivalent […]
Infectious laryngotracheitis virus (ILTV) vaccine intake evaluation by detection of virus amplification in feather pulps of vaccinated chickens.
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 37 δευτερόλεπτα
Authors: Davidson I, Raibshtein I, Altori A, Elkin N Abstract Infectious laryngotracheitis (ILT) is a respiratory disease of poultry caused by an alphaherpesvirus, ILTV. The live vaccine is applied worldwide by drinking water or by the respiratory route, and by the vent application in Israel. No system of direct evaluation of the efficacy of vaccination […]
Factors associated with a successful expansion of influenza vaccination among pregnant women in Nicaragua.
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 37 δευτερόλεπτα
CONCLUSIONS: The successful expansion of influenza vaccination among pregnant women in the municipality of Managua may be due to ready access to free medical care and health care providers’ recommendation for vaccination at health care clinics that received influenza vaccine. PMID: 26782740 [PubMed – as supplied by publisher] (Source: Vaccine) from #Medicine-SfakianakisAlexandros via o.lakala70 on […]
An investigation of the ‘female camouflage effect’ in autism using a computerized ADOS-2 and a test of sex/gender differences
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 37 δευτερόλεπτα
Abstract Background Autism spectrum conditions (autism) are diagnosed more frequently in boys than in girls. Females with autism may have been under-identified due to not only a male-biased understanding of autism but also females’ camouflaging. The study describes a new technique that allows automated coding of non-verbal mode of communication (gestures) and offers the possibility […]
Maternal plasma levels of Complement Factor H in miscarriage and in normal pregnancy. A cohort study
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 37 δευτερόλεπτα
(Source: Journal of Reproductive Immunology) from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1SB3qpN via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
Genotypic characterization of multi-drug-resistant Mycobacterium tuberculosis isolates in Myanmar
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 38 δευτερόλεπτα
Publication date: Available online 21 January 2016 Source:Journal of Infection and Chemotherapy Author(s): Khin Saw Aye, Chie Nakajima, Tomoyuki Yamaguchi, Min Min Win, Mu Mu Shwe, Aye Aye Win, Thandar Lwin, Wint Wint Nyunt, Ti Ti, Yasuhiko Suzuki The number of multi-drug-resistant tuberculosis (MDR-TB) cases is rising worldwide. As a countermeasure against this situation, the […]
RT @Telegraph : Dyes which light up cancerous cells could transform cancer treatment in the next decade https://t.co/z6iztxdfLD
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 38 δευτερόλεπτα
RT @Telegraph : Dyes which light up cancerous cells could transform cancer treatment in the next decade https://t.co/z6iztxdfLD from #AlexandrosSfakianakis via Alexandros G.Sfakianakis on Inoreader http://twitter.com/ecancer/status/690462683297112064 via IFTTT
RT @DrRobertOConnor : Quitting smoking? Only 5% of Europeans seek professional help. Wonder if due to attitudes or too few professionals htt…
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 38 δευτερόλεπτα
RT @DrRobertOConnor : Quitting smoking? Only 5% of Europeans seek professional help. Wonder if due to attitudes or too few professionals htt… from #AlexandrosSfakianakis via Alexandros G.Sfakianakis on Inoreader http://twitter.com/ecancer/status/690462527273197568 via IFTTT
RT @EuropeanCancer : Inherited genetic markers may predict melanoma survival — and help plot course of disease https://t.co/DMUOxdDpZ4 #onc…
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 38 δευτερόλεπτα
RT @EuropeanCancer : Inherited genetic markers may predict melanoma survival — and help plot course of disease https://t.co/DMUOxdDpZ4 #onc… from #AlexandrosSfakianakis via Alexandros G.Sfakianakis on Inoreader http://twitter.com/ecancer/status/690453429676810240 via IFTTT
Biomarker predicts which stage II colon cancer patients may benefit from chemotherapy
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 38 δευτερόλεπτα
A multicenter research team has identified a biomarker that predicts which stage II colon cancer patients may benefit from chemotherapy after surgery to prevent a recurrence of their disease. The study was published today in the online edition of the New… from #AlexandrosSfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1ZGu6Vh via IFTTT
The Impact of Prehospital Intubation With and Without Sedation on Outcome in Trauma Patients With a GCS of 8 or Less.
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 38 δευτερόλεπτα
Background: Although unconsciousness (Glasgow Coma Scale [GCS] 3 to 8) necessitates intubation according national guidelines, there is a notable lack of evidence to support this approach. This study evaluates the impact on outcome of prehospital intubation with and without sedation in trauma patients with a GCS of from #AlexandrosSfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1nCIFgS […]
Tramadol-Paracetamol Combination for Postoperative Pain Relief in Elective Single-level Microdisectomy Surgery.
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 38 δευτερόλεπτα
Background: The tramadol and paracetamol combination is used frequently for postoperative pain management. The literature on the use of this combination for vertebral surgery is limited. Our objective was to compare a combination of paracetamol 1 g and a lower dose of tramadol (1 mg/kg: group 1T) with a combination of paracetamol 1 g and […]
An open-label, dose-escalation study to evaluate the safety and pharmacokinetics of CEP-9722 (a PARP-1 and PARP-2 inhibitor) in combination with gemcitabine and cisplatin in patients with advanced solid tumors.
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 38 δευτερόλεπτα
Poly (ADP-ribose) polymerase-1 (PARP-1) inhibitors may potentiate chemotherapy by hindering DNA damage repair pathways. CEP-9722 is the prodrug of CEP-8983, a selective inhibitor of PARP-1 and PARP-2. Preclinical studies and a prior phase 1 study suggested that CEP-9722 may cause less myelosuppression than has been observed with other oral PARP inhibitors. The primary objective of […]
Chemosensors, Vol. 4, Pages 2: Acknowledgement to Reviewers of Chemosensors in 2015
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 38 δευτερόλεπτα
The editors of Chemosensors would like to express their sincere gratitude to the following reviewers for assessing manuscripts in 2015. […] from #AlexandrosSfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1VcZeKA via IFTTT
Pharmacogenetics driving personalized medicine: analysis of genetic polymorphisms related to breast cancer medications in Italian isolated populations
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 38 δευτερόλεπτα
Background: Breast cancer is the most common cancer in women characterized by a high variable clinical outcome among individuals treated with equivalent regimens and novel targeted therapies. In this study, we performed a population based approach intersecting high-throughput genotype data from Friuli Venezia Giulia (FVG) isolated populations with publically available pharmacogenomics information to estimate the […]
Imbalance of peripheral blood Th17 and Treg responses in children with refractory Mycoplasma pneumoniae pneumonia
sfakianakistherapeuticsστοTherapeutics Infections Emergencies MEDICINE BY ALEXANDROS G.SFAKIANAKIS,ANAPAFSEOS 5 AGIOS NIKOLAOS,CRETE 72100,GREECE,TEL :00302841026182 & 00306932607174Πριν από 38 δευτερόλεπτα
Publication date: Available online 22 January 2016 Source:Journal of Infection and Chemotherapy Author(s): Hongmei Guo, Zuhui He, Mei Li, Tingting Wang, Langfan Zhang Mycoplasma pneumoniae (MP) pneumonia is usually a benign self-limiting disease, but some patients suffer from acute lung injury in MP infections who need to use immune-modulators with conventional antibiotic treatment. The imbalance […]
Diabetic foot infection in hospitalized adults
sfakianakistherapeuticsστοTherapeutics Infections Emergencies MEDICINE BY ALEXANDROS G.SFAKIANAKIS,ANAPAFSEOS 5 AGIOS NIKOLAOS,CRETE 72100,GREECE,TEL :00302841026182 & 00306932607174Πριν από 38 δευτερόλεπτα
Publication date: Available online 21 January 2016 Source:Journal of Infection and Chemotherapy Author(s): David E. Katz, N. Deborah Friedman, Evgenia Ostrovski, Dor Ravid, Nadav Amrami, Dori Avivi, Bethlehem Mengesha, Ronit Zaidenstein, Tsilia Lazarovitch, Mor Dadon, Dror Marchaim BackgroundAcute infections of the diabetic foot (DFI) are a common and complex condition. Patients are generally managed in […]
Preterm labor and neonatal sepsis caused by intrauterine Helicobacter cinaedi infection
sfakianakistherapeuticsστοTherapeutics Infections Emergencies MEDICINE BY ALEXANDROS G.SFAKIANAKIS,ANAPAFSEOS 5 AGIOS NIKOLAOS,CRETE 72100,GREECE,TEL :00302841026182 & 00306932607174Πριν από 38 δευτερόλεπτα
Publication date: Available online 21 January 2016 Source:Journal of Infection and Chemotherapy Author(s): Yohei Maki, Seishi Furukawa, Yuki Kodama, Kaeko Sumiyoshi, Emi Kino, Hiroshi Sameshima Helicobacter cinaedi is a rare pathogen but known to cause bacteremia, cellulitis and enterocolitis. Recently, cases of involving various organs are increasingly reported such as endocarditis, meningitis, and kidney cyst […]
In vitro antimicrobial activity of benzoyl peroxide against Propionibacterium acnes assessed by a novel suscep tibility testing method
sfakianakistherapeuticsστοTherapeutics Infections Emergencies MEDICINE BY ALEXANDROS G.SFAKIANAKIS,ANAPAFSEOS 5 AGIOS NIKOLAOS,CRETE 72100,GREECE,TEL :00302841026182 & 00306932607174Πριν από 38 δευτερόλεπτα
Publication date: Available online 21 January 2016 Source:Journal of Infection and Chemotherapy Author(s): Kazuaki Okamoto, Fumiaki Ikeda, Shoji Kanayama, Akiko Nakajima, Tatsumi Matsumoto, Ritsuko Ishii, Masatoshi Umehara, Naomasa Gotoh, Naoki Hayashi, Takako Iyoda, Kaoru Matsuzaki, Satoru Matsumoto, Makoto Kawashima Benzoyl peroxide (BPO), a therapeutic agent for acne vulgaris, was assessed for in vitro antimicrobial activity […]
Evaluation of antimicrobial prophylaxis against postoperative infection after spine surgery: Limit of the first generation cephem
sfakianakistherapeuticsστοTherapeutics Infections Emergencies MEDICINE BY ALEXANDROS G.SFAKIANAKIS,ANAPAFSEOS 5 AGIOS NIKOLAOS,CRETE 72100,GREECE,TEL :00302841026182 & 00306932607174Πριν από 38 δευτερόλεπτα
Publication date: Available online 21 January 2016 Source:Journal of Infection and Chemotherapy Author(s): Yasuaki Iida, Yasuhiro Inoue, Keiji Hasegawa, Shintaro Tsuge, Yuichirou Yokoyama, Kazumasa Nakamura, Ryoichi Fukano, Ryo Takamatsu, Akihito Wada, Hiroshi Takahashi In our department, first-generation cephem (CEZ) are generally administered for 2 days as antimicrobial prophylaxis (AMP) for spinal surgery. However, the incidence […]
Genotypic characterization of multi-drug-resistant Mycobacterium tuberculosis isolates in Myanmar
sfakianakistherapeuticsστοTherapeutics Infections Emergencies MEDICINE BY ALEXANDROS G.SFAKIANAKIS,ANAPAFSEOS 5 AGIOS NIKOLAOS,CRETE 72100,GREECE,TEL :00302841026182 & 00306932607174Πριν από 38 δευτερόλεπτα
Publication date: Available online 21 January 2016 Source:Journal of Infection and Chemotherapy Author(s): Khin Saw Aye, Chie Nakajima, Tomoyuki Yamaguchi, Min Min Win, Mu Mu Shwe, Aye Aye Win, Thandar Lwin, Wint Wint Nyunt, Ti Ti, Yasuhiko Suzuki The number of multi-drug-resistant tuberculosis (MDR-TB) cases is rising worldwide. As a countermeasure against this situation, the […]
Viruses, Vol. 8, Pages 27: Acknowledgement to Reviewers of Viruses in 2015
The editors of Viruses would like to express their sincere gratitude to the following reviewers for assessing manuscripts in 2015. [...] from #Medicine via ola Kala on Inoreader http://ift.tt/1ZGuXp4 via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/23iFXO3 via IFTTT
Water, Vol. 8, Pages 34: Improving the Performance of Water Policies: Evidence from Drought in Spain
Water scarcity is a critical environmental issue worldwide, especially in arid and semiarid regions. In those regions, climate change projections suggest further reductions in freshwater supplies and increases of the recurrence, longevity and intensity of drought events. At present, one important question for policy debate is the identification of water policies that could address the mounting water scarcity problems. Suitable policies should improve economic efficiency, achieve environmental sustainability, and meet equity needs. This paper develops and applies an integrated hydr... περισσότερα »
Classification and Algorithmic Management of Constricted Ears: A 22-Year Experience.
Background: The term 'constricted ear' was coined by Tanzer. The classification and corrective methods for these malformations, however, continue to be controversial. To clarify them, we have reviewed and analyzed cases operated at our Center from January 1992 to January 2014. Methods: A total of 164 ear cases (involving 139 patients), showing features of lidded helix, compression of scapha and fossa triangularis, and/or cup-like protrusions were included in our study (constricted ear-featured microtias were excluded) and reviewed through medical records, photographs, analysis of su...περισσότερα »
Primary versus Flap Closure of Perineal Defects Following Oncologic Resection: A Systematic Review and Meta Analysis.
No abstract available from #Aesthetics via alexandrossfakianakis on Inoreader http://ift.tt/1S8SluB via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1RD0XLs via IFTTT
Eliciting cytotoxic T lymphocytes against human laryngeal cancer-derived antigens: evaluation of dendritic cells pulsed with a heat-treated tumor lysate and other antigen-loading strategies for dendritic-cell-based vaccination
Dendritic cells (DCs) have been used successfully in clinical pilot studies. However, tumor-specific immunity and clinical responses were only induced in certain cancer patients. It has been well documented th... from Cancer via ola Kala on Inoreader http://ift.tt/1nqjkH9 via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1RD0VD8 via IFTTT
3D Topographical Surface Changes in Response to Compartmental Volumization of the Medial Cheek; Defining a Malar "Augmentation Zone".
Background: Given the widespread use of facial fillers and recent identification of distinct facial fat compartments, a better understanding of 3D surface changes in response to volume augmentation is needed. Advances in 3D imaging technology now afford an opportunity to elucidate these morphological changes for the first time. Methods: A cadaver study was undertaken in which volumization of the deep medial cheek (DMC) compartment was performed at intervals up to 4cc (n=4). 3D photographs were taken following each injection in order to analyze the topographical surface changes which...περισσότερα »
Integrated analysis of microRNA regulatory network in nasopharyngeal carcinoma with deep sequencing
MicroRNAs (miRNAs) have been shown to play a critical role in the development and progression of nasopharyngeal carcinoma (NPC). Although accumulating studies have been performed on the molecular mechanisms of... from Cancer via ola Kala on Inoreader http://ift.tt/1WAcCd6 via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1RD0VmO via IFTTT
Editorial Board
Publication date: 1 February 2016 *Source:*American Journal of Infection Control, Volume 44, Issue 2 from Infection via ola Kala on Inoreader http://ift.tt/1OKzDVy via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1K0PEKg via IFTTT
Long term comparison of rib and ear cartilage grafts in autologous and allogenic fascia lata - an experimental study in a white rabbit model.
Background: Diced cartilage in fascia grafts (DCF) have become the material of choice for dorsal grafts in rhinoplasty. Allogenic fascia lata has not yet been investigated as isolated fascial graft or as a combined graft with ear and rib cartilage, especially in comparison to autologous fascia and over a long implantation period. Methods: 10 different grafts were built from either autologous or allogenic fascia lata alone or as DCFs with diced costal or ear cartilage and implanted into the dorsal skin of 15 rabbits. After 3 or 9 months the grafts were explanted and histologically ana... περισσότερα »
An adenovirus 4 outbreak amongst staff in a pediatric ward manifesting as keratoconjunctivitis—a possible failure of contact and aerosol infection control
Publication date: Available online 21 January 2016 *Source:*American Journal of Infection Control Author(s): Elizabeth Hoyle, Joanne C. Erez, Helen R. Kirk-Granger, Elizabeth Collins, Julian W. Tang An adenovirus serotype 4 outbreak was identified on a pediatric ward involving 4 members of the health care staff. Two inpatients on the ward at the time (1 immunocompromised) were shedding this virus from their respiratory tracts and could have acted as independent index cases for the staff infections. Significantly, upon investigation, it was found that staff members were unaware that ...περισσότερα »
Neuropilin-1 is associated with clinicopathology of gastric cancer and contributes to cell proliferation and migration as multifunctional co-receptors
Neuropilin-1 (NRP-1) is a transmembrane glycoprotein participating in the growth and metastasis of cancer cells as multifunctional co-receptors by interacting with the signaling pathways. However, its role in ... from Cancer via ola Kala on Inoreader http://ift.tt/1nqjmi2 via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1RD0XLm via IFTTT
Long-term follow-up of quality of life following DIEP flap breast reconstruction.
Background: Sequelae due to breast cancer are very high and negatively impact patient quality of life (QoL). Although deep inferior epigastric perforator (DIEP) flap has become a standard for autologous breast reconstruction (BR), there are limited data regarding long-term QoL. This study aimed to measure patient QoL more than 5 years after DIEP flap BR and compare the finding with two French reference samples. Methods: A cross-sectionnal study of QoL was performed in women who underwent DIEP flap BR between 1995 and 2007 using the Medical Outcomes Study 36-item short-form health su...περισσότερα »
Investigation of ototoxicity of artesunate as add-on therapy in patients with metastatic or locally advanced breast cancer: new audiological results from a prospective, open, uncontrolled, monocentric phase I study
Abstract Purpose Artesunate (ART) has been used for a long time in the treatment of *Plasmodium falciparum* malaria and has been considered safe. The present phase I study aimed to determine the daily dose of ART that is well tolerated as add-on therapy in patients with breast cancer for 4 weeks of therapy. Ototoxicity could be a potential safety concern in settings different from malaria. Therefore, comprehensive audiological assessment was essential. Methods The ARTIC M33/2 study was a prospective, open, uncontrolled, monocentric phase I dose-escalation study to evaluate the saf... περισσότερα »
APIC Masthead
Publication date: 1 February 2016 *Source:*American Journal of Infection Control, Volume 44, Issue 2 from Infection via ola Kala on Inoreader http://ift.tt/1OKzG3K via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1K0PEKe via IFTTT
Information for Readers
Publication date: 1 February 2016 *Source:*American Journal of Infection Control, Volume 44, Issue 2 from Infection via ola Kala on Inoreader http://ift.tt/23iCrTQ via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1KuemO7 via IFTTT
Three-dimensional computed tomographic angiographic study of the inter-perforator flow of the lower leg.
Background: The area perfused by a single perforator depends on its perforasome and its unique inter-perforator flow pattern. The purpose of this study was to clarify the inter-perforator flow patterns of the peroneal and posterior tibial artery perforators (PA-Ps, PTA-Ps) using three-dimensional computed tomographic angiography (3D-CTA). Methods: Thirteen whole leg skin flaps were harvested in the subfacial plane from fresh cadavers. PA-Ps, PTA-Ps, anterior tibial, and sural artery perforators (ATA-Ps, SA-Ps) with a diameter greater than 0.5 mm were documented. 3D-CTA with an injec... περισσότερα »
Defining quality in healthcare and measuring quality in Surgery.
Quality in healthcare has been sluggish to adapt to the changing landscape, leading to lapses in the successful delivery of care. Consequently, quality of care has come under intense scrutiny in the past decade resulting in the creation of various federally-funded and non-profit org anizations aimed at assessing and implementing systematic quality improvements. In this article, we examine the evolution of quality in healthcare relative to established quality control measures in other sectors, different ways to assess quality, and the current state of our healthcare system. (C)2016Am... περισσότερα »
Infection surveillance systems in primary health care: A literature review
Publication date: Available online 21 January 2016 *Source:*American Journal of Infection Control Author(s): Mary Lou Manning, Monika Pogorzelska-Maziarz The Patient Protection and Affordable Care Act of 2010 is placing primary care at the epicenter of accountability of US health care delivery. There is a significant body of evidence characterizing the value of acute-care hospital infection surveillance systems. Given the central role primary care is beginning to play, we were interested in examining the use of infection surveillance systems in primary care practice. Our review of th... περισσότερα »
Information for Authors
Publication date: 1 February 2016 *Source:*American Journal of Infection Control, Volume 44, Issue 2 from Infection via ola Kala on Inoreader http://ift.tt/23iCsXD via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/20iDr7Z via IFTTT
Comments on "A Cadaveric Study Comparing the Efficacy of the Sheen Spreader Graft and the Fulcrum Spreader Graft".
No abstract available from #Aesthetics via alexandrossfakianakis on Inoreader http://ift.tt/1NoKRgF via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1RD0XuW via IFTTT
Reducing abdominal seroma after DIEP flap breast reconstruction, outcomes in 726 patients.
No abstract available from #Aesthetics via alexandrossfakianakis on Inoreader http://ift.tt/1S8SgqW via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1RD0Vmz via IFTTT
Message from APIC - February 2016
Publication date: 1 February 2016 *Source:*American Journal of Infection Control, Volume 44, Issue 2 from Infection via ola Kala on Inoreader http://ift.tt/1OKzG3G via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1RD0Vmx via IFTTT
Eluxadoline for irritable bowel syndrome with diarrhea
Alexandros G. SfakianakisστοNews in OtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 55 δευτερόλεπτα
New England Journal of Medicine from #Medicine via ola Kala on Inoreader http://ift.tt/1ZGuW4u via IFTTT
Advances in the management of HIV/HCV coinfection
Alexandros G. SfakianakisστοNews in OtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 55 δευτερόλεπτα
Hepatology International from #Medicine via ola Kala on Inoreader http://ift.tt/1ZR7oPC via IFTTT
PDLIM1 stabilizes the E-cadherin/β-catenin complex to prevent epithelial-mesenchymal transition and metastatic potential of colorectal cancer cells
Alexandros G. SfakianakisστοNews in OtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 55 δευτερόλεπτα
Cancer Research from #Medicine via ola Kala on Inoreader http://ift.tt/1ZGuTFI via IFTTT
Integrated genomic analysis of pancreatic ductal adenocarcinomas reveals genomic rearrangement events as significant drivers of disease
Alexandros G. SfakianakisστοNews in OtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 55 δευτερόλεπτα
Cancer Research from #Medicine via ola Kala on Inoreader http://ift.tt/1ZR7pmP via IFTTT
Neonatal vascularisation and oxygen tension regulate appropriate perinatal renal medulla / papilla maturation
Abstract Congenital medullary dysplasia with obstructive nephropathy is a common congenital disorder observed in paediatric patients and represents the foremost cause of renal failure. However, the molecular processes regulating normal papillary outgrowth during the postnatal period are unclear. In this study, transcriptional profiling of the renal medulla across postnatal development revealed enrichment of non-canonical Wnt signalling, vascular development and planar cell polarity genes, all of which may contribute to perinatal medulla / papilla maturation. These pathways were in... περισσότερα »
The Impact of Prehospital Intubation With and Without Sedation on Outcome in Trauma Patients With a GCS of 8 or Less.
Background: Although unconsciousness (Glasgow Coma Scale [GCS] 3 to 8) necessitates intubation according national guidelines, there is a notable lack of evidence to support this approach. This study evaluates the impact on outcome of prehospital intubation with and without sedation in trauma patients with a GCS of from Anaesthesia via ola Kala on Inoreader http://ift.tt/1nCIFgS via IFTTT
Tramadol-Paracetamol Combination for Postoperative Pain Relief in Elective Single-level Microdisectomy Surgery.
Background: The tramadol and paracetamol combination is used frequently for postoperative pain management. The literature on the use of this combination for vertebral surgery is limited. Our objective was to compare a combination of paracetamol 1 g and a lower dose of tramadol (1 mg/kg: group 1T) with a combination of paracetamol 1 g and a higher dose of tramadol (1.5 mg/kg: group 1.5T) for postoperative pain after microdisectomy surgery. Our main outcome measure was Visual Analogue Scale pain scores for 4 hours postoperatively. Methods: This prospective randomized triple-blind clin...περισσότερα »
Trichoscopy as an additional tool for the differential diagnosis of tinea capitis
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 55 δευτερόλεπτα
Abstract Current recommendations advise the use of mycological examination to confirm the diagnosis of tinea capitis (TC).1 However, culture may take up to 6 weeks, postponing treatment in some cases. This delay might have epidemiological impact given the associated risk of contagion. Trichoscopy has been suggested as a fast and inexpensive tool to diagnose TC. […]
Topical sodium metabisulfite for the treatment of calcinosis cutis: A promising new therapy
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 55 δευτερόλεπτα
Summary Calcinosis cutis is a chronic calcium-mediated disease, which causes significant morbidity for patients. Multiple treatments have been tried, with varying results. Indeed, to date, no standard treatment has been generally accepted. Sodium metabisulfite is an inorganic compound that when reacts with oxygen becomes sodium sulfate, a metabolite of sodium thiosulfate, that has a similar […]
Neuropilin-1 is associated with clinicopathology of gastric cancer and contributes to cell proliferation and migration as multifunctional co-receptors
Neuropilin-1 (NRP-1) is a transmembrane glycoprotein participating in the growth and metastasis of cancer cells as multifunctional co-receptors by interacting with the signaling pathways. However, its role in ... from Cancer via ola Kala on Inoreader http://ift.tt/1nqjmi2 via IFTTT
Investigation of ototoxicity of artesunate as add-on therapy in patients with metastatic or locally advanced breast cancer: new audiological results from a prospective, open, uncontrolled, monocentric phase I study
Abstract Purpose Artesunate (ART) has been used for a long time in the treatment of *Plasmodium falciparum* malaria and has been considered safe. The present phase I study aimed to determine the daily dose of ART that is well tolerated as add-on therapy in patients with breast cancer for 4 weeks of therapy. Ototoxicity could be a potential safety concern in settings different from malaria. Therefore, comprehensive audiological assessment was essential. Methods The ARTIC M33/2 study was a prospective, open, uncontrolled, monocentric phase I dose-escalation study to evaluate the saf... περισσότερα »
Journal Club: Impact of rapid screening for discontinuation of methicillin-resistant Staphylococcus aureus contact precautions
Publication date: Available online 21 January 2016 *Source:*American Journal of Infection Control Author(s): Kathleen A. Gase, Sara M. Reese from Infection via ola Kala on Inoreader http://ift.tt/23iCrTD via IFTTT
Risk factors and outcomes of hospitalized patients with blood infections caused by multidrug-resistant Acinetobacter baumannii complex in a hospital of Northern China
Publication date: Available online 21 January 2016 *Source:*American Journal of Infection Control Author(s): Ninghui Guo, Wencheng Xue, Dahai Tang, Jinya Ding, Bin Zhao The purpose of this study was to determine the risk factors and outcomes of bloodstream infections caused by multidrug-resistant (MDR) Acinetobacter baumannii complex in a hospital of Northern China. Risk factors associated with MDR A baumannii complex included older age, pneumonia, using drainage catheters, and intensive care unit stay. Multivariate analysis showed that multidrug resistance and mechanical ventilation...περισσότερα »
Pneumocystis pneumonia outbreak among renal transplant recipients at a North American transplant center: Risk factors and implications for infection control
Publication date: Available online 21 January 2016 *Source:*American Journal of Infection Control Author(s): Sunita Mulpuru, Greg Knoll, Colleen Weir, Marc Desjardins, Daniel Johnson, Ivan Gorn, Todd Fairhead, Janice Bissonnette, Natalie Bruce, Baldwin Toye, Kathryn Suh, Virginia Roth BackgroundPneumocystis pneumonia is a severe opportunistic fungal infection. Outbreaks among renal transplant recipients have been reported in Europe and Japan, but never in North America.MethodsWe conducted a retrospective case–control study among adult renal transplant recipients at a Canadian center... περισσότερα »
Chemosensors, Vol. 4, Pages 2: Acknowledgement to Reviewers of Chemosensors in 2015
The editors of Chemosensors would like to express their sincere gratitude to the following reviewers for assessing manuscripts in 2015. […] from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1VcZeKA via IFTTT
Systemic CNS Delivery of NPY for Alzheimer Disease Cell Biology
Neuropeptide Y (NPY) is one of the most abundant protein transmitters in the central nervous system with roles in a variety of biological functions including: food intake, cardiovascular regulation, cognition, seizure activity, circadian rhythms, and neurogenesis. Reduced NPY and NPY receptor expression is associated with numerous neurodegenerative disorders including Alzheimer disease (AD). To determine whether… Continue reading Systemic CNS Delivery of NPY for Alzheimer Disease Cell Biology
Response to Cragg et al. Letter to the Editor.
No abstract available from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1S8Sgad via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1nd8LWZ via IFTTT
FDA Mulls Parameters for Allergy Therapies
(MedPage Today) — Researching allergy treatments tough in young children and infants (Source: MedPage Today Allergy) from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1OBvW6U via IFTTT
Willingness to Pay for CT Colonography: A Survey of Patient Preferences
American Journal of Roentgenology, Volume 206, Issue 2, Page 355-358, February 2016. from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1PIxARK via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174 from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1SB1yxl via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis… Continue reading Willingness to Pay for CT Colonography: A Survey of Patient Preferences
Classification and Algorithmic Management of Constricted Ears: A 22-Year Experience.
Background: The term ‘constricted ear’ was coined by Tanzer. The classification and corrective methods for these malformations, however, continue to be controversial. To clarify them, we have reviewed and analyzed cases operated at our Center from January 1992 to January 2014. Methods: A total of 164 ear cases (involving 139 patients), showing features of lidded… Continue reading Classification and Algorithmic Management of Constricted Ears: A 22-Year Experience.
Supernumerary Kidneys Do Exist!
American Journal of Roentgenology, Volume 206, Issue 2, Page W48-W48, February 2016. from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1PIxzgL via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174 from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1OBtlcU via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis… Continue reading Supernumerary Kidneys Do Exist!
Primary versus Flap Closure of Perineal Defects Following Oncologic Resection: A Systematic Review and Meta Analysis.
No abstract available from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1S8SluB via IFTTT
3D Topographical Surface Changes in Response to Compartmental Volumization of the Medial Cheek; Defining a Malar «Augmentation Zone».
Background: Given the widespread use of facial fillers and recent identification of distinct facial fat compartments, a better understanding of 3D surface changes in response to volume augmentation is needed. Advances in 3D imaging technology now afford an opportunity to elucidate these morphological changes for the first time. Methods: A cadaver study was undertaken in… Continue reading 3D Topographical Surface Changes in Response to Compartmental Volumization of the Medial Cheek; Defining a Malar «Augmentation Zone».
Should We Remove Divided Hepatic Venous Territory Retaining Portal Flow?
We read with great interest the article by Kurihara and colleagues1 in which the authors describe resection of the right hepatic vein (RHV) drainage area for treatment of tumors close to the RHV using indocyanine green (ICG)-fluorescence imaging. They identified veno-occlusive regions after clamping the proper hepatic artery and the RHV and entirely removed them… Continue reading Should We Remove Divided Hepatic Venous Territory Retaining Portal Flow?
Reply to “Imaging of Tuberous Sclerosis”
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
American Journal of Roentgenology, Volume 206, Issue 2, Page W43-W43, February 2016. from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1PIxzx9 via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
The Copyright Transfer Agreement: New Modifications Beginning in June 2016
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
American Journal of Roentgenology, Volume 206, Issue 2, Page 229-229, February 2016. from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1PIxARU via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
Section Editor’s Notebook: Women’s Imaging and Value-Driven Radiology—“Welcome to the Club!”
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
American Journal of Roentgenology, Volume 206, Issue 2, Page 236-237, February 2016. from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1Qp2cwk via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
JOURNAL CLUB: Scatter Radiation Dose From Digital Screening Mammography Measured in a Representative Patient Population
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
American Journal of Roentgenology, Volume 206, Issue 2, Page 359-365, February 2016. from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1PIxARQ via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
Integrating Customer Intimacy Into Radiology to Improve the Patient Perspective: The Case of Breast Cancer Screening
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
American Journal of Roentgenology, Volume 206, Issue 2, Page 265-269, February 2016. from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1Qp2cwi via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
False-Positive Tumor Enhancement After Cryoablation of Renal Cell Carcinoma: A Prospective Study
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
American Journal of Roentgenology, Volume 206, Issue 2, Page 332-339, February 2016. from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1PIxARM via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
Differences in Liver Imaging and Reporting Data System Categorization Between MRI and CT
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
American Journal of Roentgenology, Volume 206, Issue 2, Page 307-312, February 2016. from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1Qp2aok via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
Medicolegal—Malpractice and Ethical Issues in Radiology.
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
American Journal of Roentgenology, Volume 206, Issue 2, Page W41-W41, February 2016. from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1PIxzgR via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
Supernumerary Kidneys Do Exist!
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
American Journal of Roentgenology, Volume 206, Issue 2, Page W48-W48, February 2016. from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1PIxzgL via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
Willingness to Pay for CT Colonography: A Survey of Patient Preferences
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
American Journal of Roentgenology, Volume 206, Issue 2, Page 355-358, February 2016. from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1PIxARK via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
Reply to “Imaging of Tuberous Sclerosis”
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 1 ώρα
American Journal of Roentgenology, Volume 206, Issue 2, Page W43-W43, February 2016. from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1PIxzx9 via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174 from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1SB1A8m via IFTTT
Long-term follow-up of quality of life following DIEP flap breast reconstruction.
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 1 ώρα
Background: Sequelae due to breast cancer are very high and negatively impact patient quality of life (QoL). Although deep inferior epigastric perforator (DIEP) flap has become a standard for autologous breast reconstruction (BR), there are limited data regarding long-term QoL. This study aimed to measure patient QoL more than 5 years after DIEP flap BR […]
The Copyright Transfer Agreement: New Modifications Beginning in June 2016
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 1 ώρα
American Journal of Roentgenology, Volume 206, Issue 2, Page 229-229, February 2016. from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1PIxARU via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174 from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1SB1A8h via IFTTT
Three-dimensional computed tomographic angiographic study of the inter-perforator flow of the lower leg.
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 1 ώρα
Background: The area perfused by a single perforator depends on its perforasome and its unique inter-perforator flow pattern. The purpose of this study was to clarify the inter-perforator flow patterns of the peroneal and posterior tibial artery perforators (PA-Ps, PTA-Ps) using three-dimensional computed tomographic angiography (3D-CTA). Methods: Thirteen whole leg skin flaps were harvested in […]
Section Editor’s Notebook: Women’s Imaging and Value-Driven Radiology—“Welcome to the Club!”
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 1 ώρα
American Journal of Roentgenology, Volume 206, Issue 2, Page 236-237, February 2016. from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1Qp2cwk via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174 from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1SB1zRZ via IFTTT
Defining quality in healthcare and measuring quality in Surgery.
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 1 ώρα
Quality in healthcare has been sluggish to adapt to the changing landscape, leading to lapses in the successful delivery of care. Consequently, quality of care has come under intense scrutiny in the past decade resulting in the creation of various federally-funded and non-profit org anizations aimed at assessing and implementing systematic quality improvements. In this […]
JOURNAL CLUB: Scatter Radiation Dose From Digital Screening Mammography Measured in a Representative Patient Population
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 1 ώρα
American Journal of Roentgenology, Volume 206, Issue 2, Page 359-365, February 2016. from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1PIxARQ via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174 from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1OBtld4 via IFTTT
Comments on «A Cadaveric Study Comparing the Efficacy of the Sheen Spreader Graft and the Fulcrum Spreader Graft».
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 1 ώρα
No abstract available from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1NoKRgF via IFTTT
Integrating Customer Intimacy Into Radiology to Improve the Patient Perspective: The Case of Breast Cancer Screening
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 1 ώρα
American Journal of Roentgenology, Volume 206, Issue 2, Page 265-269, February 2016. from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1Qp2cwi via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174 from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1OBtjBX via IFTTT
Reducing abdominal seroma after DIEP flap breast reconstruction, outcomes in 726 patients.
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 1 ώρα
No abstract available from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1S8SgqW via IFTTT
Effect of visual biofeedback to acquire supraglottic swallow in healthy individuals: a randomized-controlled trial.
The aim of this study is to evaluate the effect of visual biofeedback therapy in acquiring supraglottic swallow (SGS) in a randomized-controlled trial with healthy individuals. Eighteen individuals (mean age, 26 years) who could not close or keep closed the vocal folds before and during the swallow in SGS were allocated randomly to either a visual biofeedback group (eight individuals) or a nonbiofeedback group (10 individuals). A videoendoscope was inserted intranasally and an SGS exercise, using 4 ml of green-colored water, was performed 30 times per day up to 5 days. When the part... περισσότερα »
The Mini-BESTest: a review of psychometric properties.
The Mini-Balance Evaluation Systems Test (Mini-BESTest) has been identified as the most comprehensive balance measure for community-dwelling adults and elderly individuals. It can be used to assess balance impairments in several other conditions, mainly Parkinson's disease and stroke. Despite increasing use of the Mini-BESTest since it was first published 5 years ago, no systematic review synthesizing its psychometric properties is available. The aim of this study was to provide a comprehensive review of the psychometric properties of the Mini-BESTest when administered to patients w... περισσότερα »
Trichoscopy as an additional tool for the differential diagnosis of tinea capitis
Abstract Current recommendations advise the use of mycological examination to confirm the diagnosis of tinea capitis (TC).1 However, culture may take up to 6 weeks, postponing treatment in some cases. This delay might have epidemiological impact given the associated risk of contagion. Trichoscopy has been suggested as a fast and inexpensive tool to diagnose TC. However, specific dermoscopic patterns remain to be established. This article is protected by copyright. All rights reserved. from #Dermatology via alexandrossfakianakis on Inoreader http://ift.tt/1OBsucr via IFTTT
Topical sodium metabisulfite for the treatment of calcinosis cutis: A promising new therapy
Summary Calcinosis cutis is a chronic calcium-mediated disease, which causes significant morbidity for patients. Multiple treatments have been tried, with varying results. Indeed, to date, no standard treatment has been generally accepted. Sodium metabisulfite is an inorganic compound that when reacts with oxygen becomes sodium sulfate, a metabolite of sodium thiosulfate, that has a similar ability to inhibit calcium oxalate agglomeration. Four female patients diagnosed with calcinosis cutis, secondary to dermatomyositis, systemic sclerosis and radiodermitis after breast cancer we... περισσότερα »
Segmental ureteroileal conduit resection for the treatment of distal upper urinary tract recurrence of bladder cancer following cystectomy
Segmental ureterectomy is less invasive than radical nephroureterectomy and results in nephron preservation and satisfactory tumor control. This study was to determine the feasibility of segmental ureteroileal... from Cancer via ola Kala on Inoreader http://ift.tt/1RYcxkw via IFTTT
Patient’s Education Before Mastectomy Influences the Rate of Reconstructive Surgery
Abstract Breast reconstruction (BR) should be offered and discussed to each woman with breast cancer who planned for mastectomy, except the cases with severe comorbidities. However, the majority of these patients do not undergo reconstructive surgery. A 20-question survey was administered to a group of 50 women (age 29–83 years, median 53) treated with mastectomy. 22.4 % underwent reconstruction of the breast, 24.5 % declared an interest in BR in the future, 53.1 % were not interested in reconstructive surgery. 51.2 % obtained information concerning BR before surgery, 58.1 % after ... περισσότερα »
Family history of breast cancer and its association with disease severity and mortality
Abstract A family history (FH) of breast cancer (BC) is known to increase an individual's risk of disease onset. However, its role in disease severity and mortality is less clear. We aimed to ascertain associations between FH of BC, severity and BC-specific mortality in a hospital-based cohort of 5354 women with prospective information on FH. We included women diagnosed at Guy's and St Thomas' NHS Foundation Trust between 1975 and 2012 (*n* = 5354). BC severity was defined and categorized as good, moderate, and poor prognosis. Data on BC-specific mortality was obtained from the Nat...περισσότερα »
OtoRhinoLaryngology & Medicine,New Articles,January 22nd,2016
Robot-Assisted Stereoelectroencephalography Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 1 λεπτό Technique, Results, and Complications Related to Robot-Assisted Stereoelectroencephalography: BACKGROUND: Robot-assisted stereoelectroencephalography (SEEG) may represent a simplified, precise, and safe alternative to the more traditional SEEG techniques. OBJECTIVE: To report our clinical experience with robotic SEEG implantation and to define its utility in the management of patients with medically refractory epilepsy. METHODS: The prospective obse... περισσότερα »
Dysembryoplastic Neuroepithelial Tumor of the Septum Pellucidum and the Supratentorial Midline: Histopathologic, Neuroradiologic, and Molecular Features of 7 Cases.
Dysembryoplastic neuroepithelial tumors (DNTs) are one of the most common epilepsy-associated low-grade glioneuronal tumors of the central nervous system. Although most DNTs occur in the cerebral cortex, DNT-like tumors with unusual intraventricular or periventricular localizations have been reported. Most of them involve the septum pellucidum and the foramen of Monro. In this study, we have described the neuroradiologic, histopathologic, and molecular features of 7 cases (4 female and 3 male; patient age range, 3 to 34 y; mean age, 16.7 y). The tumors, all localized near the suprat...περισσότερα »
Differentiation of Fibroadenomas and Pure Mucinous Carcinomas on Dynamic Contrast-Enhanced MRI of the Breast Using Volume Segmentation for Kinetic Analysis: A Feasibility Study
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
American Journal of Roentgenology, Volume 206, Issue 2, Page 253-258, February 2016. from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1Qp2cfY via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
Unenhanced CT and MRI Parameters That Can Be Used to Reliably Predict Fat-Invisible Angiomyolipoma
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
American Journal of Roentgenology, Volume 206, Issue 2, Page 340-347, February 2016. from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1RCWYys via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
Diaphragm Recruitment Increases during a Bout of Targeted Inspiratory Muscle Training.
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Purpose: The extent to which the diaphragm is targeted during a bout of inspiratory muscle training (IMT) is unknown. The purpose of this study was to characterize the relative activation patterns of the diaphragm and extra-diaphragmatic inspiratory muscles during a bout of IMT and to determine if diaphragmatic recruitment can be increased by giving subjects […]
Packing and Problematic Feeding Behaviors in CHARGE Syndrome: A Qualitative Analysis
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Publication date: Available online 21 January 2016 Source:International Journal of Pediatric Otorhinolaryngology Author(s): Alexandra Hudson, Meghan Macdonald, Kim Blake ObjectiveTo understand packing and problematic feeding behaviors during mealtime in individuals with CHARGE syndrome. Packing, or holding food in one’s cheeks without swallowing, is an adverse feeding behavior that has been described in children with autism […]
“ScreenIT”: Computerized screening of swallowing, nutrition and distress in head and neck cancer patients during (chemo)radiotherapy
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Publication date: Available online 21 January 2016 Source:Oral Oncology Author(s): Laurelie R. Wall, Bena Cartmill, Elizabeth C. Ward, Anne J. Hill, Elizabeth Isenring, Joshua Byrnes, Suzanne Chambers, Jeff Dunn, Jodie Nixon, Jane Whelan, Sandro V. Porceddu BackgroundIn light of growing service demands, the use of computerized screening processes have been proposed to optimize patient triage […]
Utility of a perioperative nutritional intervention on postoperative outcomes in high-risk head & neck cancer patients
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Publication date: Available online 21 January 2016 Source:Oral Oncology Author(s): Nicholas R. Rowan, Jonas T. Johnson, Christina E. Fratangelo, Brenda K. Smith, Patricia A. Kemerer, Robert L. Ferris ObjectivesInvestigate both the utility and feasibility of perioperative nutritional supplementation with an arginine-enriched immunonutrition formula to high-risk head and neck cancer surgical patients and examine its effects […]
Significant frequency of MSH2/MSH6 abnormality in ovarian endometrioid carcinoma supports a histotype-specific Lynch syndrome screening in ovarian carcinomas
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Abstract Aims Lynch syndrome screening in ovarian carcinoma is controversial. This study aims to assess the frequency of deficient mismatch repair protein (dMMR) in a retrospective cohort enriched for non-high-grade serous carcinomas and its association with outcome within histological types. Methods and results Tissue microarrays representing 612 ovarian carcinomas were tested for mismatch repair proteins […]
Overexpression of Eukaryotic Initiation Factor 5A2 is associated with cancer progression and poor prognosis in patients with early-stage cervical cancer
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Abstract Aims As one of the only two isoforms of the EIF5A family, the Eukaryotic initiation factor 5A2 (EIF5A2) plays an important role in tumor progression and prognosis evaluation. This study aimed to investigate EIF5A2 expression in International Federation of Gynecology and Obstetrics (FIGO) stage I–II cervical cancer and to evaluate its clinical significance. Methods […]
Multicentre prospective evaluation of implant-assisted mandibular removable partial dentures: surgical and prosthodontic outcomes
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Abstract Objective To determine implant survival and prosthodontic maintenance of implant-assisted mandibular removable partial dentures in a multicentre prospective study up to 10 years. Materials and methods Forty-eight participants with mandibular distal extension partial dentures were selected. A control group of 12 New Zealand participants had new conventional mandibular partial dentures made. Three test groups […]
The effect of hydrothermal spark discharge anodization in the early integration of implants in sheep sinuses
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Abstract Objectives Spark discharge anodic oxidation forms a porous oxide film on titanium implant surfaces, which may increase surface roughness and enhance early osseointegration. This study aimed to clinically and histomorphometric compare commercially-available sandblasted (RBM) implants, treated with hydrothermal anodization and placed into an animal maxillary sinus model. Materials and Methods Thirty 3.75 mm × […]
Dynamics of salivary cortisol in chronic kidney disease patients at stages 1 through 4
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Abstract Context End-stage renal disease has been associated with derangement of the HPA function. The dynamics of this axis in early stages of renal disease (CKD) has not been assessed. Objectives To evaluate in patients with CKD at stages 1-4 (KDOQI): the diurnal variation of salivary cortisol; the suppressibility of cortisol in saliva and serum […]
Polymorphisms of the GR and HSD11B1genes influence body mass index and weight gain during hormone replacement treatment in patients with Addison’s disease
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Abstract Objective Glucocorticoid substitution is essential in patients with chronic primary adrenocortical insufficiency (Addison’s disease) and both over-treatment and inadequate dosage have deleterious effects. Individual sensitivity to glucocorticoids is partly genetically determined. Context To test the hypothesis whether the well-characterized SNPs of the GR and HSD11B1 genes may modulate the individual sensitivity to exogenous glucocorticoids […]
IJERPH, Vol. 13, Pages 150: Acknowledgement to Reviewers of IJERPH in 2015
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
The editors of IJERPH would like to express their sincere gratitude to the following reviewers for assessing manuscripts in 2015. […] from #AlexandrosSfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1SAWokV via IFTTT
Family history of breast cancer and its association with disease severity and mortality
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Abstract A family history (FH) of breast cancer (BC) is known to increase an individual’s risk of disease onset. However, its role in disease severity and mortality is less clear. We aimed to ascertain associations between FH of BC, severity and BC-specific mortality in a hospital-based cohort of 5354 women with prospective information on FH. […]
Pretreatment serum interleukin-1β, interleukin-6, and tumor necrosis factor-α levels predict the progression of colorectal cancer
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Abstract The correlations of pretreatment serum concentrations of proinflammatory cytokines such as interleukin (IL)-1β, IL-6, and tumor necrosis factor-α (TNFα) with the clinicopathologic features and progression of colorectal cancer (CRC) were investigated. The pretreatment serum levels of IL-1β, IL-6, and TNFα were measured in 164 CRC patients before treatment. The relationships between changes in proinflammatory […]
The outcomes of newly diagnosed elderly multiple myeloma patients treated at a single U.S. institution
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Abstract Improvements in the outcomes of elderly multiple myeloma (MM) patients have lagged behind those of transplant-eligible patients, likely due in part to the use of less efficacious melphalan-containing regimens. To date, there are very limited data for the outcomes of elderly MM patients in the United States (US), particularly for novel agent-containing triplet regimens. […]
Eosinophilic esophagitis is characterized by a non-IgE-mediated food hypersensitivity
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Abstract Eosinophilic esophagitis (EoE) is a chronic disease characterized clinically by symptoms of esophageal dysfunction and histologically by eosinophil-predominant inflammation. EoE is frequently associated with concomitant atopic diseases and immunoglobulin E (IgE) sensitization to food allergens in children as well as to aeroallergens and cross-reactive plant allergen components in adults. Patients with EoE respond well […]
Eosinophilic esophagitis is characterized by a non-IgE-mediated food hypersensitivity
sfakianakismedicsστοORL ALLERGY AESTHETICS ANATOMY Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Abstract Eosinophilic esophagitis (EoE) is a chronic disease characterized clinically by symptoms of esophageal dysfunction and histologically by eosinophil-predominant inflammation. EoE is frequently associated with concomitant atopic diseases and immunoglobulin E (IgE) sensitization to food allergens in children as well as to aeroallergens and cross-reactive plant allergen components in adults. Patients with EoE respond well […]
Myeloid Cell Nuclear Differentiation Antigen (MNDA) Expression Distinguishes Extramedullary Presentations of Myeloid Leukemia From Blastic Plasmacytoid Dendritic Cell Neoplasm.
Myeloid neoplasms constitute one of the most common malignancies in adults. In most cases these proliferations initially manifest in the blood and marrow; however, extramedullary involvement may precede blood or marrow involvement in a subset of cases, making a definitive diagnosis challenging by morphologic and immunohistochemical assessment alone. Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare, aggressive entity that frequently presents in extramedullary sites and can show morphologic and immunophenotypic overlap with myeloid neoplasms. Given that BPDCN and myeloid...περισσότερα »
Frequent BRAF V600E Mutations in Metanephric Stromal Tumor.
No abstract available from Anatomy Pathology via xlomafota13 on Inoreader http://ift.tt/1QiDxaR via IFTTT
Significant frequency of MSH2/MSH6 abnormality in ovarian endometrioid carcinoma supports a histotype-specific Lynch syndrome screening in ovarian carcinomas
[image: cover.gif?v=1&s=8da50c92b06d5da1183f2623] Abstract Aims Lynch syndrome screening in ovarian carcinoma is controversial. This study aims to assess the frequency of deficient mismatch repair protein (dMMR) in a retrospective cohort enriched for non-high-grade serous carcinomas and its association with outcome within histological types. Methods and results Tissue microarrays representing 612 ovarian carcinomas were tested for mismatch repair proteins (MLH1, PMS2, MSH2, and MSH6) by immunohistochemistry. dMMR was detected in 13.8% of endometrioid and 2.4% of clear cell carc... περισσότερα »
Overexpression of Eukaryotic Initiation Factor 5A2 is associated with cancer progression and poor prognosis in patients with early-stage cervical cancer
[image: cover.gif?v=1&s=8da50c92b06d5da1183f2623] Abstract Aims As one of the only two isoforms of the EIF5A family, the Eukaryotic initiation factor 5A2 (EIF5A2) plays an important role in tumor progression and prognosis evaluation. This study aimed to investigate EIF5A2 expression in International Federation of Gynecology and Obstetrics (FIGO) stage I–II cervical cancer and to evaluate its clinical significance. Methods and results The mRNA and protein expression levels of EIF5A2 were analyzed in 20 tissue samples of FIGO stage I–II cervical cancer tissues and paired surroundi... περισσότερα »
Diagnostic clues for FNA diagnosis of intranodal palisaded myofibroblastoma, a rare benign lesion, an introspective case report
Intranodal palisaded myofibroblastoma (IPM) is a benign entity, characterized by intranodal proliferation of cells of myofibroblastic origin. It has five distinct histologic features: compressed remnants of lymphoid tissue at the periphery, spindle cells with nuclear palisading, intralesional hemorrhage, amianthoid fibers, and intracellular and extracellular fuchsinophilic bodies. The spindle cells are SMA and vimentin (IHC) positive and are negative for S 100, and has a low proliferative index. Cytologic diagnosis of this lesion is a diagnostic challenge and has to be differenti... περισσότερα »
Cytologic diagnosis of coccidioidomycosis: Spectrum of findings in Southern Arizona patients over a 10 year period
Background The largest series examining the cytological diagnosis of coccidioidomycosis was reported more than 20 years ago and only considered fine needle aspiration (FNA) specimens from pulmonary nodules. Since then, there has been a substantial increase in the incidence of the disease in endemic regions. The aims of this study were to examine the spectrum of Coccidioides in all cytologic specimens and detail their diagnostic and clinical features. The prevalence of infection is also examined against temperature and precipitation data. Methods The Department of Pathology datab...περισσότερα »
The cytopathology of mycobacterial infection
Mycobacterial infection, tuberculosis (TB) in particular, remains one of the world's deadliest communicable diseases in adults and particularly in children, in low and middle income countries. The combination of human immunodeficiency virus (HIV) and TB is often lethal with TB accounting for 25% of deaths in the HIV population. One of the cornerstones for reducing the TB epidemic is early case detection using high quality diagnostic techniques. Cytology, especially fine needle aspiration biopsy (FNAB) is able to diagnose mycobacterial infection in a rapid and cost-effective manne... περισσότερα »
Going beyond “Basaloid neoplasm”: Fine needle aspiration cytology of epithelial-myoepithelial carcinoma of the parotid gland
Epithelial-myoepithelial carcinoma (EMC) is a rare salivary gland malignancy with variable cytologic findings. Its rarity, variable morphologic findings, and similarities with more common salivary gland entities make it a difficult cytologic diagnosis. As the name signifies, the key feature of this tumor is presence of an epithelial and myoepithelial component. However, when one of these two components is scant on the fine needle aspiration (FNA) smears, it may be overlooked. We present a case from a 62 year-old female who presented to the clinic with a parotid nodule and episode... περισσότερα »
Local muscle flaps via video-assisted thoracoscopic surgery (VATS) without thoracotomy for dead space obliteration
Abstract The obliteration of intra-thoracic dead space following tumor or empyema extirpation is imperative to successful long-term outcomes. We sought to describe the technique of using a pedicled *latissmus dorsi* muscle flap for obliteration of a large 14 × 6cm intrathoracic dead space following pleural decortication of chronic empyema, without thoracotomy or rib spreading via video-assisted thoracoscopic surgery (VATS). Specific attention is directed to the technical details of the flap harvest and inset in relation to the modifications required to inset the flap without a tho... περισσότερα »
Ligature induced peri-implantitis: tissue destruction and inflammatory progression in a murine model
Abstract Objectives The aim of this study was to investigate tissue destruction and inflammatory progression of ligature-induced peri-implantitis in mice and to establish an alternative murine model of peri-implantitis. Material and methods Sixty male C57BL/6NCrSlc mice (4-week-old) were used and the maxillary right first molars were extracted. Eight weeks after extraction, custom-made pure titanium machined screw type implants (0.8 × 1.5 mm) were placed, one implant per animal. Four weeks later, 5-0 silk ligatures were applied around implant necks to induce peri-implantitis. Ani... περισσότερα »
Comparison of conventional twist drill protocol and piezosurgery for implant insertion: an ex vivo study on different bone types
Abstract Objective The aim of this *ex vivo* study was to compare implant insertion procedures using piezosurgery and conventional drilling in different qualities of bone. Implant bed preparation time, generated heat, and primary implant stability were analyzed. Material and methods Fresh *ex vivo* porcine bone block samples (cancellous, mixed, and cortical bone) were obtained. The bone quality was quantified by ultrasound transmission velocity (UTV). Each bone sample received three implants of the same diameter using each of the techniques of piezosurgery and conventional twist... περισσότερα »
In vitro cleaning potential of three implant debridement methods. Simulation of the non-surgical approach
Abstract Objectives To assess the cleaning potential of commonly used implant debridement methods, simulating non-surgical peri-implantitis therapy *in vitro*. Materials and methods One-hundred-and-eighty dental implants were ink-stained and mounted in combined soft and hard tissue models, representing peri-implantitis defects with angulations of 30, 60, and 90° covered by a custom-made artificial mucosa. Implants were treated by a dental school graduate and a board-certified periodontist for 120 s with following instruments: Gracey curette, ultrasonic scaler, and an air powder a... περισσότερα »
The influence of initial mucosal thickness on crestal bone change in similar macrogeometrical implants: a prospective randomized clinical trial
Abstract Objective The objective of this study was to evaluate crestal bone changes around bone- and tissue-level implants related to initial mucosal thickness. Materials and methods Patients received at least 2 implants: one with the prosthetic abutment connection at the crestal bone level (MC) and one with the prosthetic abutment connection at 2.5 mm *supra* crestal (LC). Flap thickness measurements were taken using a periodontal probe after raising the buccal flap. Patients were divided into 2 groups according to the mucosal thickness—Group A (thickness, ≤2 mm) and Group B (th... περισσότερα »
Effects of different lasers on organic/inorganic ratio of radicular dentin
Abstract The aim of this study was to evaluate the chemical stability of endodontic-treated root dentin after different laser irradiations through Raman spectroscopy. Fifty maxillary canines were selected and prepared with K3 system. Roots were randomly distributed into five groups (*n* = 10) according to the surface treatment: GI (water), GII (NaOCl + EDTA), GIII (NaOCl + EDTA + 980 nm Diode laser), GIV (NaOCl + EDTA+ 1064 nm Nd: YAG laser) and GV (NaOCl + EDTA+ 2780 nm Er,Cr: YSGG laser). Lasers were applied for 20 s. Samples were bisected, and the organic and inorganic content ...περισσότερα »
Same strategy for pitfalls of radiotherapy in different anatomical districts
Abstract Oral mucositis (OM) and radiodermatitis (RD) are serious side effects of radiotherapy (RT), often leading to its suspension, need for analgesics, and enteral/parenteral nutrition. Laser therapy is becoming a recommended treatment option. This prospective study aimed at demonstrating the beneficial effect of class IV laser therapy (HPLT) on RT-induced OM, an off-label use of HPLT to treat RD in breast cancer patients. Fifty-three cancer patients, during/after RT and/or chemotherapy (CT), affected by OM, were treated with HPLT during four consecutive days (970 ± 15 nm, 5 W ...περισσότερα »
A novel approach for in-office tooth bleaching with 6 % H 2 O 2 /TiO_N and LED/laser system—a controlled, triple-blinded, randomized clinical trial
Abstract The purpose of this randomized, parallel, triple-blinded clinical trial was to compare efficacy and tooth sensitivity (TS) after use of an in-office bleaching agent of 6 % hydrogen peroxide containing nanoparticles of nitrogen-doped titanium oxide (HP6) vs. 35 % hydrogen peroxide (HP35). Forty-eight volunteers were randomly divided either a HP6 or HP35. Two clinical sessions were performed with an interval of 7 days between them for each group. In each session, two consecutive applications of each bleaching agent were performed and activated by a hybrid LED/laser light. E... περισσότερα »
Effects of non-ablative fractional erbium glass laser treatment on gene regulation in human three-dimensional skin models
Abstract Clinical experiences with non-ablative fractional erbium glass laser therapy have demonstrated promising results for dermal remodelling and for the indications of striae, surgical scars and acne scars. So far, molecular effects on human skin following treatment with these laser systems have not been elucidated. Our aim was to investigate laser-induced effects on skin morphology and to analyse molecular effects on gene regulation. Therefore, human three-dimensional (3D) organotypic skin models were irradiated with non-ablative fractional erbium glass laser systems enabling ... περισσότερα »
The long-term effect of 1550 nm erbium:glass fractional laser in acne vulgaris
Abstract We evaluated the short-term and long-term effects of the 1550 nm erbium:glass (Er:glass) fractional laser in the treatment of facial acne vulgaris. Forty-five (9 male and 36 female) acne patients were treated 4 times at 4-week intervals with the following parameters: 169 spot density and 15–30 mJ/cm2 fluence. There was no control group. The laser spots were adjustable (maximum overlap: 20 %) according to the treatment area, and delivered in rows in order to cover all the face. Clinical photographs were taken. The IGA scores and lesion counts were performed for each treatme... περισσότερα »
Evaluation of different laser wavelengths on ablation lesion and residual thermal injury in intervertebral discs of the lumbar spine
Abstract Laser discectomy or nucleotomy is an increasingly important method for less invasive procedures of column, but the ideal kind of laser is still not established. As the wavelength is an important parameter for water absorption, this study was performed to investigate the action of the laser emission in the near infrared (808 to 1908 nm) region in the context of surgical procedures for percutaneous intervertebral disc decompression (nucleotomy). Forty intervertebral discs from pigs lumbar spines were irradiated with laser (*λ* = 808, 980, 1470 and 1908 nm), 1-s on/off time ... περισσότερα »
Useful Parameters for Distinguishing Subcutaneous Panniculitis-like T-Cell Lymphoma From Lupus Erythematosus Panniculitis.
Some cases of subcutaneous panniculitis-like T-cell lymphoma (SPTCL) and lupus erythematosus panniculitis (LEP) demonstrate clinical and histopathologic overlap, raising the possibility that they represent opposite ends of a disease spectrum. SPTCL, however, is typically associated with greater morbidity and risk for hemophagocytic lymphohistiocytosis (HLH); therefore, diagnostic distinction is clinically important. We present the histopathologic, immunophenotypic, and molecular findings with long-term clinical follow-up of 13 patients with SPTCL (median, 64 mo follow-up) and 7 with...περισσότερα »
Squamoid Eccrine Ductal Carcinoma: A Clinicopathologic Study of 30 Cases.
Squamoid eccrine ductal carcinoma is a poorly documented skin adnexal carcinoma showing squamous and duct differentiation. It is regarded to be of low-grade malignant potential, but limited follow-up information is available. To study their clinical behavior and histologic features, 30 squamoid eccrine ductal carcinomas were identified from departmental and referral files. Hematoxylin and eosin-stained sections were reviewed, and immunohistochemistry for carcinoembryonic antigen and epithelial membrane antigen was examined to confirm duct differentiation. Clinical follow-up was obta...περισσότερα »
Pretreatment serum interleukin-1β, interleukin-6, and tumor necrosis factor-α levels predict the progression of colorectal cancer
Abstract The correlations of pretreatment serum concentrations of proinflammatory cytokines such as interleukin (IL)-1*β*, IL-6, and tumor necrosis factor-*α* (TNF*α*) with the clinicopathologic features and progression of colorectal cancer (CRC) were investigated. The pretreatment serum levels of IL-1*β*, IL-6, and TNF*α* were measured in 164 CRC patients before treatment. The relationships between changes in proinflammatory cytokine and C-reactive protein (CRP) levels and both clinicopathologic variables and disease progression were examined by univariate and multivariate analysi... περισσότερα »
The outcomes of newly diagnosed elderly multiple myeloma patients treated at a single U.S. institution
Abstract Improvements in the outcomes of elderly multiple myeloma (MM) patients have lagged behind those of transplant-eligible patients, likely due in part to the use of less efficacious melphalan-containing regimens. To date, there are very limited data for the outcomes of elderly MM patients in the United States (US), particularly for novel agent-containing triplet regimens. In this retrospective study at a single U.S. institution, the outcomes of 117 consecutive newly diagnosed, symptomatic MM patients over the age of 70 were evaluated. The median age was 75 years (range 70–95)... περισσότερα »
An open-label, dose-escalation study to evaluate the safety and pharmacokinetics of CEP-9722 (a PARP-1 and PARP-2 inhibitor) in combination with gemcitabine and cisplatin in patients with advanced solid tumors.
Poly (ADP-ribose) polymerase-1 (PARP-1) inhibitors may potentiate chemotherapy by hindering DNA damage repair pathways. CEP-9722 is the prodrug of CEP-8983, a selective inhibitor of PARP-1 and PARP-2. Preclinical studies and a prior phase 1 study suggested that CEP-9722 may cause less myelosuppression than has been observed with other oral PARP inhibitors. The primary objective of this study was to determine the maximum-tolerated dose of CEP-9722 in combination with gemcitabine and cisplatin in patients with advanced solid tumors. All patients received cisplatin 75 mg/m2 on day 1 an... περισσότερα »
Determinants of disease-specific health-related quality of life in Turkish stroke survivors.
Stroke is a worldwide cause of morbidity and mortality that affects health-related quality of life. In this study, our objective was to identify determinants of disease-specific health-related quality of life in Turkish stroke survivors. A total of 114 consecutive patients who experienced a stroke at least 6 months earlier were studied. Health-related quality of life was measured using Stroke-specific Quality of Life (SS-QoL) consisting of 12 domains. Demographic and clinical data were collected, including age, sex, marital status, years of education, time since stroke, whether the ... περισσότερα »
Chemosensors, Vol. 4, Pages 2: Acknowledgement to Reviewers of Chemosensors in 2015
The editors of Chemosensors would like to express their sincere gratitude to the following reviewers for assessing manuscripts in 2015. [...] from #Medicine via ola Kala on Inoreader http://ift.tt/1VcZeKA via IFTTT
Electronics, Vol. 5, Pages 6: Acknowledgement to Reviewers of Electronics in 2015
The editors of Electronics would like to express their sincere gratitude to the following reviewers for assessing manuscripts in 2015. [...] from #Medicine via ola Kala on Inoreader http://ift.tt/1P9SXPF via IFTTT
Approach-motivated pregoal states enhance the reward positivity
Abstract Past work has demonstrated that the reward positivity (RewP) indexes a performance-monitoring system sensitive to positive outcomes. However, studies have not investigated how approach-motivated states occurring in goal pursuit influence performance monitoring. Using a modified monetary incentive delay task, participants played a reaction time game evoking approach-motivated pregoal (reward trials) or neutral (no-reward trials) states. Then, they received trial feedback resulting in monetary gain or no gain. Results revealed that the RewP was larger to win feedback on rewa... περισσότερα »
The Mini-BESTest: a review of psychometric properties.
Alexandros G. SfakianakisστοRehabilitation,Sports and Exercise Medicine by Alexandros G. SfakianakisΠριν από 1 ώρα
The Mini-Balance Evaluation Systems Test (Mini-BESTest) has been identified as the most comprehensive balance measure for community-dwelling adults and elderly individuals. It can be used to assess balance impairments in several other conditions, mainly Parkinson's disease and stroke. Despite increasing use of the Mini-BESTest since it was first published 5 years ago, no systematic review synthesizing its psychometric properties is available. The aim of this study was to provide a comprehensive review of the psychometric properties of the Mini-BESTest when administered to patients w... περισσότερα »
Determinants of disease-specific health-related quality of life in Turkish stroke survivors.
Alexandros G. SfakianakisστοRehabilitation,Sports and Exercise Medicine by Alexandros G. SfakianakisΠριν από 1 ώρα
Stroke is a worldwide cause of morbidity and mortality that affects health-related quality of life. In this study, our objective was to identify determinants of disease-specific health-related quality of life in Turkish stroke survivors. A total of 114 consecutive patients who experienced a stroke at least 6 months earlier were studied. Health-related quality of life was measured using Stroke-specific Quality of Life (SS-QoL) consisting of 12 domains. Demographic and clinical data were collected, including age, sex, marital status, years of education, time since stroke, whether the ... περισσότερα »
