08:43
Use of Computed Tomography-Derived Prosthetics for Intraoperative Guidance of Tumor Resection: Abstract: Preoperative computed tomography (CT)-derived design and modeling provides a useful guide for a more accurate reconstruction of a variety of complex maxillofacial deformities. While the use of three-dimensional...
08:42
Comparison of Cellular Alterations in Fat Cells Harvested With Laser-Assisted Liposuction and Suction-Assisted Liposuction: Objective: The aim of the present study was to evaluate the viability and proliferative capacity of adipose-derived stem cells obtained by laser-assisted liposuction (LAL).Methods:...
08:42
Comparative Analysis of the Magnetic Resonance Imaging Features Between Anaplastic Meningioma and Atypical Meningioma: Objectives: The aim of the study was to investigate the differences in the imaging feature between anaplastic meningioma (World Health Organization grade III) and atypical meningioma...
08:41
Long-Term Assessment of Introduction: Techniques for treating trigonocephaly and anterior plagiocephaly have evolved from the initial suturectomy technique to frontal cranioplasty. The authors evaluated the suturectomy technique in adolescent patients with these craniosynostoses, by carrying out a retrospective,...
08:40
Progressive Limitation in Mouth Opening: Jacob Disease: Creutzfeldt–Jakob diseaseFrom Wikipedia, the free encyclopediaCreutzfeldt–Jakob diseaseTonsil biopsy in variant CJD. Prion protein immunostaining.Classification and external resourcesSpecialtyNeurologyICD-10A81.0,F02.1ICD-9-CM046.1OMIM123400MedlinePlus000788eMedicineneuro/725Patient...
08:37
Therapeutic Effects of Sildenafil on Experimental Mandibular Fractures: Objectives: No previous studies have examined the effect of sildenafil on fracture healing. This study was designed to investigate the effect of sildenafil on the fracture healing process.Methods: Thirty-six female Sprague-Dawley...
08:35
Reconstruction of Full-Thickness Eyelid Defects Following Malignant Tumor Excision: The Retroauricular Flap and Palatal Mucosal Graft: Abstract: Treatment of malignant periorbital tumors requires radical resection of the tumor, which can result in the creation of major eyelid defects. Reconstruction...
08:35
Pediatric National Surgical Quality Improvement Program: Useful for Quality Improvement in Craniosynostosis Surgery?: Abstract: The American College of Surgeons and the American Pediatric Surgical Association collaborate to provide pediatric hospitals with multispeciality surgical outcomes data through...
08:34
Assessing the Anatomical Variability of Deep Circumflex Iliac Vessels in Harvesting of Iliac Crest-Free Flap for Mandibular Reconstruction: Abstract: In this study, the authors’ aims were to measure the length and location of branching of the pedicle from iliac artery, to describe the anatomical variability...
08:33
Versión en españolWhat is hand, foot and mouth disease?Hand, foot and mouth disease is a viral infection caused by a strain of Coxsackie virus. It causes a blister-like rash that, as the name implies, involves the hands, feet and mouth. (Hand, foot and mouth disease is different than foot-and-mouth disease,...
08:32
Bornholm diseaseFrom Wikipedia, the free encyclopediaBornholm diseaseClassification and external resourcesSpecialtyInfectious diseaseICD-10B33.0ICD-9-CM074.1DiseasesDB29152eMedicinearticle/300049MeSHD011000Bornholm disease or epidemic pleurodynia or epidemic myalgia[1] is a disease caused by the Coxsackie...
08:31
From Wikipedia, the free encyclopediaCoxsackie B virusCoxsackie B4 virusVirus classificationGroup:Group IV ((+)ssRNA)Family:PicornaviridaeGenus:EnterovirusSpecies:Enterovirus BSubtypeCoxsackie B virusCoxsackie B is the name of a group of six serotypes of Coxsackievirus, a pathogenic enterovirus, that...
08:29
Coxsackie A virusFrom Wikipedia, the free encyclopediaCoxsackie A virusVirus classificationGroup:Group IV ((+)ssRNA)Family:PicornaviridaeGenus:EnterovirusSpecies:Enterovirus ASubtypeCoxsackie A virusCoxsackie A virus (CAV) is a cytolytic Coxsackievirus of the Picornaviridae family, an enterovirus (a...
08:27
DNA virusHerpesviridaeAlphaHSVHerpes simplexHerpetic whitlowHerpes gladiatorumHerpetic keratoconjunctivitisHerpetic sycosisNeonatal herpes simplexHerpes genitalisHerpes labialisEczema herpeticumHerpetiform esophagitisHerpes B virusB virus infectionVZVChickenpoxHerpes zosterHerpes zoster oticusOphthalmic...
08:21
Surgical Treatment Outcomes of Head and Neck Lymphatic Malformations in Patients With a Variety of Ages and Unusual Sites: Objective: The objective of this study was to review the clinical characteristics and surgical treatment outcomes of head and neck lymphatic malformations and to define the risk...
08:21
Failure of Maxillary Reconstruction With Freeze-Dried Bone Allograft: Abstract: Bone reconstruction to reestablish bone width and height is required in case of bone atrophy. A 45-year-old white woman was referred to the oral clinical surgery of Aracatuba Dental School, University Estadual Paulista—UNESP,...
08:21
A Long-term Assessment: Abstract: The authors aimed to accurately assess the donor site morbidity from iliac crest bone grafts for secondary bone grafting in patients with cleft lip and palate alveolar defects. Fifty patients between 3 months and 10 years following alveolar bone grafting for cleft lip...
08:20
in a 17-Year-Old Child: Abstract: Thyroglossal duct cyst is a frequent event; however, papillary carcinoma within a thyroglossal duct cyst is rare, particularly in children. A 17-year-old girl presented with an asymptomatic mid-submental mass for the last 2 months. The diagnosis of thyroglossal duct...
08:20
An Outcomes Comparison Between Autologous and Alloplastic Cranioplasty in the Pediatric Population: Background: The use of alloplastic material in cranial reconstruction has been well described in the adult population, especially when a paucity of autologous tissue exists. In children it is unknown how...
08:20
in Previously Irradiated Scalp: Background: Temperoparietal scalp defects are fairly common resulting from varied array of etiology. Various reconstructive options exisit, but the aim was to achieve a reliable and simple solution keeping in mind the principle of replacing “like with like.”Methods: The...
08:19
Clinical Usefulness of The objective of this study was to evaluate usefulness of mandibular reconstructions using custom-made titanium mesh (Ti-mesh) tray and particulate cancellous bone and marrow (PCBM). Consecutive 21 patients who underwent mandibular reconstruction were enrolled in this study. They...
08:18
Clinical Features and Treatment of Distal Intracranial Aneurysms: Abstract: To analyze the clinical characteristics, therapies, and outcomes of distal intracranial aneurysms, the authors retrospectively studied the clinical and imaging data of 18 patients with distal intracranial aneurysms. There were...
08:18
Kimura Disease Presenting as Forehead Soft Mass:
08:17
Is Early Nasal Shaping With a Limited Alar Base Incision Possible in the Repair of Cleft Lips?: Abstract: The repair of cleft lips has an important place in plastic and reconstructive surgery. In the treatment of these deformities, the aim was to restore the normal lip morphology in the cleft area as...
08:16
Upward Migration of an Asymptomatic Lower Second Molar to the Coronoid Process:
08:15
Versatility of Distraction Osteogenesis for the Craniofacial Skeleton: AbstractAbstract: Malformations of the craniofacial skeleton are common. Restoration of anatomic shape, size, and position has been traditionally accomplished using autologous bone grafting to fill gaps created by surgery and segmental...
08:13
Meta-analysis of the Incidence of : Introduction: Bilateral sagittal split osteotomy is a relatively common maxillofacial surgical procedure. The most commonly reported complication is neurosensory disturbances (NSD). The inferior alveolar nerve is by far the most commonly affected but sporadic reports...
08:13
for Surgical Training: Abstract: Craniosynostosis has a relatively low incidence in the general population and its treatment requires cautious approaches. For these reasons, patients are usually referred to several specialists or a medical center. Therefore, most trainees and young surgeons do not have...
08:13
Obtained by a Filtration Process of the Adipose Tissue: Abstract: In this work, the authors will discuss about a new protocol and rapid alternative to isolate the mesenchymal stromal cells from the stromal vascular fraction, without the use of collagenase, to regenerate the bone tissue in the maxillo-facial...
08:12
Huge Abstract: To the authors’ knowledge, most of intracranial arachnoid cyst located in middle cranial fossa and lateral fissure cistern. So, huge frontal-temporal lobe arachnoid cyst is rare. Symptoms of arachnoid cyst may be atypical, including headache, nausea, vomiting, epilepsy, poor memory, and...
08:12
Feasibility and Advantage of a Background: For a safe and reliable middle skull base reconstruction, the temporalis muscle flaps or pericranial-temporalis muscle flaps have usually been used as the first-choice in clinical practice. But these flaps have an inevitable disadvantage, namely, temporal hollowing....
08:11
Aberrant Internal Carotid Artery: A Rare Cause of Dysphagia:
08:04
Epinephrine Injection in Greater Palatine Canal: An Alternative Technique for Reducing Hemorrhage During Septoplasty: Objective: Obtaining adequate hemostasis during otolaryngology operations is necessary because a small amount of blood can be problematic and obscure the visual field. The authors aimed...
08:03
A Demographic Analysis Outside an Urban Environment: Background: Metopic craniosynostosis has traditionally been cited as the third most common type of isolated synostosis, after sagittal and coronal craniosynostosis. Recently, several urban institutions have observed an increase in the incidence of...
08:03
: a prospective study of 15 patientsvia Oral and Maxillofacial SurgeryPublication date: Available online 11 May 2016Source:International Journal of Oral and Maxillofacial SurgeryAuthor(s): S.E. Nørholt, J. HartlevThe objective of this study was to evaluate the outcome of the surgical treatment of osteonecrosis...
08:03
Mumps Presenting as a Parotid Abscess: Abstract: Parotid abscess is an uncommon condition in infants. It is frequently associated with prematurity, prolonged gavage feeding, and dehydration. Mumps is a viral disease caused by paramyxovirus. It frequently involves the parotid gland and is only rarely...
08:02
Patterns of Pediatric Maxillofacial Injuries: Abstract: Facial trauma in children and adolescents is reported to range from 1% to 30%. Because of many anatomical, physiological, and psychological characteristics of the pediatric population, maxillofacial injuries in children should be treated with special...
08:02
Evaluation of gingival crevicular fluid cyclophilin a and extracellular matrix metalloproteinase inducer levels in different periodontal diseasesvia Oral BiologyPublication date: August 2016Source:Archives of Oral Biology, Volume 68Author(s): Gülnihal Eren, Oya Türkoğlu, Harika Atmaca, Gül AtillaObjectiveCyclophilin...
08:01
Diagnosis and evaluation of 100 dysphagia patients using videoendoscopy at a core hospital of a local city in Japan: AbstractJapan has entered an era of a super-aging population, and given the importance of oral nutrition, the need to evaluate swallowing function has increased. Herein, we contribute...
08:01
Mathematical beta function formulation for maxillary arch form prediction in normal occlusion population: AbstractThe aim of this study was to assess the dental arch curvature in subjects with normal occlusion in an Iranian population and propose a beta function formula to predict maxillary arch form...
08:00
Salivary mucinous adenocarcinoma of the mandible: AbstractMucinous adenocarcinoma (MAC) is a malignancy rarely affecting the salivary glands, with fewer than 30 cases described in the medical literature. MAC is mostly observed in the minor salivary glands of the palate, and to date, no case of salivary...
08:00
Cariogenicity features of Streptococcus mutans in presence of rubusoside: AbstractBackgroundOne promising way of reducing caries is by using sucrose substitutes in food. rubusoside is a prototype sweet substance isolated from the leaves of the plant Rubrus suavissimus S. Lee. (Rosaceae), and is rated...
07:59
Investigation of the Immediate Effects of Humming on Vocal Fold Vibration Irregularity Using Electroglottography and High-speed Laryngoscopy in Patients With Organic Voice Disordersvia VoicePublication date: Available online 10 May 2016Source:Journal of VoiceAuthor(s): Carien Vlot, Makoto Ogawa, Kiyohito...
07:58
in a Tubular Three-dimensional Computational Laryngeal Modelvia VoicePublication date: Available online 10 May 2016Source:Journal of VoiceAuthor(s): Qian Xue, Xudong ZhengObjectiveThe current study used a three-dimensional (3D) computational laryngeal model to investigate the effect of false vocal folds...
07:57
The role of mitochondrial sirtuins in health and diseaseFree Radic Biol Med. 2016 May 6;Authors: Osborne B, Bentley NL, Montgomery MK, Turner NAbstract Mitochondria play a critical role in energy production, cell signalling and cell survival. Defects in mitochondrial function contribute to the...
07:57
in multitalker scenariosa): Spatial separation of talkers is known to improve speech intelligibility in a multitalker scenario. A contribution of binaural unmasking, in addition to a better-ear effect, is usually considered to account for this advantage. Binaural unmasking is assumed to result from...
07:56
Large-scale training to increase speech intelligibility for hearing-impaired listeners in novel noises: Supervised speech segregation has been recently shown to improve human speech intelligibility in noise, when trained and tested on similar noises. However, a major challenge involves the ability to...
07:56
Receptive language as a predictor of cochlear implant outcome for prelingually deaf adults: 10.3109/14992027.2016.1157269<br/>Alexandra RoussetObjective: This study investigated outcomes and predictive factors, specifically language skills, for a group of prelingually hearing-impaired adults who...
07:55
in Adults Who Do and Do Not Stutter? Evidence From a Dual-Task Paradigm: PurposeThe present study examined whether engaging working memory in a secondary task benefits speech fluency. Effects of dual-task conditions on speech fluency, rate, and errors were examined with respect to predictions derived...
06:51
H Gayathri, Sutrave Satyananda Rao Indian Journal of Otology 2016 22(2):110-118 Background and Objectives: Intratympanic gentamicin therapy is an effective modality for control of vertigo in Meniere's disease (MD) and when given in low concentration (<30 mg/mL), once weekly minimizes its side effects...
06:50
Rajagopalan Raman Indian Journal of Otology 2016 22(2):143-143 from #ORL via xlomafota13 on Inoreader http://ift.tt/1TAuKjH via IFTTT
06:50
Chronic craniofacial pain involves the head, face and oral cavity and is associated with significant morbidity and high levels of health care utilization. A bidirectional relationship is suggested in the literature for poor sleep and pain, and craniofacial pain and sleep are reciprocally related. We...
06:50
Abstract This article reports a case of piloleiomyoma of external auditory canal, which is the 7th case of leiomyoma of the external auditory canal being reported and the 2nd case of leiomyoma arising from arrectores pilorum muscles, all the other five cases were angioleiomyomas, arising from blood...
06:45
Previous studies on the relationship between olfaction and depression have revealed mixed results. In addition, few have focused on the reciprocity of this association. The aim of this study is to combine depression and olfactory data in two separate patient populations to further understand their association....
06:45
Priming describes the principle of modified stimulus perception that occurs due to a previously presented stimulus. Although we have begun to understand the mechanisms of crossmodal priming, the concept of intramodal olfactory priming remains relatively unexplored. Therefore, we applied positive and...
02:51
Abstract Studies with humans and other mammals have provided support for a two-channel representation of horizontal ("azimuthal") space in the auditory system. In this representation, location-sensitive neurons contribute activity to one of two broadly tuned channels whose responses are compared to...
02:51
Publication date: August 2016Source:Archives of Oral Biology, Volume 68 Author(s): Gülnihal Eren, Oya Türkoğlu, Harika Atmaca, Gül Atilla ObjectiveCyclophilin A (CypA) is able to regulate inflammatory responses and matrix metalloproteinase production via its interaction with extracellular matrix metalloproteinase...
02:51
Condition: Squamous Cell Carcinoma of the Head and NeckInterventions: Drug: Pembrolizumab; Other: PlaceboSponsors: Ezra Cohen; Merck Sharp & Dohme Corp.Not yet recruiting - verified May 2016 from #ORL via xlomafota13 on Inoreader http://ift.tt/1Oi3fza via IFTTT
02:51
Conditions: Thyroid Papillary Carcinoma; ThyroidectomyInterventions: Procedure: The Axillary Bilateral-breast Approach; Procedure: The bilateral Axillo-breast ApproachSponsor: Jinan Military General HospitalRecruiting - verified May 2016 from #ORL via xlomafota13 on Inoreader http://ift.tt/1ZFpAr4...
02:51
Cada vez existe una evidencia más clara de que algunos cuadros psiquiátricos o psicológicos pueden estar ligados a las disfunciones tiroideas. Las alteraciones funcionales de la glándula tiroides pueden comprometer al sistema nervioso central, lo que puede originar una sintomatología que se debe diferenciar...
02:51
Las mujeres embarazadas y en edad fértil se encuentran en los grupos de riesgo a tener en cuenta cuando se habla de disfunciones tiroideas. La Sociedad Española de Endocrinología y Nutrición y la Sociedad Española de Ginecología y Obstetricia recomiendan hacer un exhaustivo seguimiento durante el embarazo...
02:51
Las alteraciones de la función tiroidea pueden ser transitorias o permanentes. Cuando se inicia un tratamiento sustitutivo o de reemplazo con hormona tiroidea en el hipotiroidismo crónico, el tratamiento suele ser de por vida, por lo que es fundamental mantener el hábito de tomar los comprimidos que...
02:51
Desde Cuida tu tiroides tenemos un propósito claro, conocer la enfermedad tiroidea para poder tratarla de modo temprano, lo cual impedirá que perdamos una buena calidad de vida. El hipertiroidismo es una disfunción de la glándula tiroides con unos síntomas inespecíficos que bien podrían confundirse con...
02:51
Cuando se diagnostica un hipotiroidismo congénito mediante la prueba de sangre del talón al medir T4 y/o TSH entre los días 1 a 4 de vida del bebé, se recomienda iniciar lo más rápido posible, antes de las 2 semanas de vida, el tratamiento sustitutivo o de reemplazo con tiroxina para normalizar los niveles...
02:51
Los síntomas de disfunción tiroidea pueden aparecer de modo paulatino y en ocasiones pueden confundirse con otras dolencias. Debemos tener en cuenta que la patología tiroidea, puede comenzar con pequeñas molestias, que no llaman la atención pero que acabarán convirtiéndose en síntomas que afectarán a...
02:51
La cirugía de la glándula tiroides o tiroidectomía se realiza generalmente por los siguientes motivos: Como tratamiento de la tirotoxicosis, por enfermedad de Graves o por bocio nodular o multinodular tóxicos, especialmente cuando no es conveniente el tratamiento con yodo radiactivo como ocurre en...
02:51
La glándula tiroides es un órgano especialmente importante pues está vinculado con el funcionamiento de gran parte del organismo. En el caso de las mujeres, además, está ligada a su ciclo reproductivo, es asi qué el índice de disfunción tiroidea aumenta durante tres fases especialmente importantes: el...
02:51
Cuando se descubre uno o más nódulos tiroideos (bocio nodular o multinodular) se iniciarán los estudios para diagnosticar cuál es la alteración que los causa. Las pruebas de función tiroidea, la ecografía con o sin punción para el estudio citológico y eventualmente gammagrafía tiroidea, orientarán al...
02:51
Abstract Studies with humans and other mammals have provided support for a two-channel representation of horizontal ("azimuthal") space in the auditory system. In this representation, location-sensitive neurons contribute activity to one of two broadly tuned channels whose responses are compared to...
02:51
Tras el diagnóstico de hipotiroidismo llega el momento de iniciar el tratamiento para recuperar la calidad de vida y evitar problemas más graves de salud que, a largo plazo, suelen derivar de la disfunción tiroidea. El paciente debe aprender a convivir con los comprimidos de tiroxina sintética, la cual...
02:51
Purpose The present study examined whether engaging working memory in a secondary task benefits speech fluency. Effects of dual-task conditions on speech fluency, rate, and errors were examined with respect to predictions derived from three related theoretical accounts of disfluencies. Method Nineteen...
02:50
Abstract Studies with humans and other mammals have provided support for a two-channel representation of horizontal ("azimuthal") space in the auditory system. In this representation, location-sensitive neurons contribute activity to one of two broadly tuned channels whose responses are compared to...
02:50
10.3109/14992027.2016.1157269<br/>Alexandra Rousset from #Audiology via xlomafota13 on Inoreader http://ift.tt/24Luy9a via IFTTT
02:50
A technique useful for performing derating at acoustic powers where significant harmonic generation occurs is illustrated and validated with experimental measurements. The technique was previously presented using data from simulations. The method is based upon a Gaussian representation of the propagation...
02:50
In this paper an effective meshless method is proposed to solve time-harmonic acoustic problems defined on unbounded domains. To this end, the near field is discretized by a set of nodes and the far field effect is taken into account by considering radiative boundary conditions. The approximation...
02:50
Supervised speech segregation has been recently shown to improve human speech intelligibility in noise, when trained and tested on similar noises. However, a major challenge involves the ability to generalize to entirely novel noises. Such generalization would enable hearing aid and cochlear implant...
02:50
A case of a 55 year old woman with iatrogenic vocal cord trauma and sleep related symptoms is reported. In particular this case highlights sleep disordered breathing as a delayed complication after iatrogenic vocal cord trauma. The patient developed acute stridor from a contralateral vocal cord hematoma...
02:50
• Despite limited evidence, quetiapine is commonly used for insomnia• A systematic, comprehensive search revealed one small randomized, controlled trial of quetiapine for primary insomnia• This paper resolves uncertainty in the evidence base that was present in previous non-systematic reviews• There...
01:49
Abstract The aim of this study was to investigate the relation of serum monocyte to serum HDL cholesterol ratio with obstructive sleep apnea syndrome (OSAS). A total of 336 patients who underwent polysomnography (PSG) were included in this study. The individuals with an apnea hypopnea index (AHI) <5/h...
01:48
• We determined visual and automated REM sleep without atonia (RSWA) diagnostic cut-offs for idiopathic REM sleep behavior disorder (iRBD) patients with comorbid obstructive sleep apnea (OSA) during split-night polysomnography.• Combining analysis of phasic muscle activity burst durations with standard...
01:48
Spatial separation of talkers is known to improve speech intelligibility in a multitalker scenario. A contribution of binaural unmasking, in addition to a better-ear effect, is usually considered to account for this advantage. Binaural unmasking is assumed to result from the spectro-temporally simultaneous...
01:48
Publication date: July 2016Source:International Journal of Pediatric Otorhinolaryngology, Volume 86 Author(s): Krista C. Ritchie, Jill Chorney, Paul Hong ObjectiveThe aim of this study was to describe the level of decisional conflict experienced by parents considering surgery for their children and...
01:48
• Delayed Sleep-Wake Phase Disorder and Non 24-Hour Sleep-Wake Rhythm Disorder patients indicate significantly higher Neuroticism scores and significantly lower Extraversion, Agreeableness & Conscientiousness scores relative to healthy counterparts.• The observed personality traits in DSWPD patients...
01:48
Perfluorocarbon droplets that are capable of an ultrasound-mediated phase transition have applications in diagnostic and therapeuticultrasound. Techniques to modify the droplet size distribution are of interest because of the size-dependent acoustic response of the droplets. Differential centrifugation...
01:48
• 45 children with sleep disordered breathing, ages ranging from 3 to 14 years, not pre-selected based on any type of facial morphology or cephalometric measure, underwent bimaxillary expansion.• The majority of the children (66%) showed improvement in their sleep scores and symptoms after bimaxillary...
01:48
Perfluorocarbon droplets that are capable of an ultrasound-mediated phase transition have applications in diagnostic and therapeuticultrasound. Techniques to modify the droplet size distribution are of interest because of the size-dependent acoustic response of the droplets. Differential centrifugation...
01:48
Related Articles The role of mitochondrial sirtuins in health and disease. Free Radic Biol Med. 2016 May 6; Authors: Osborne B, Bentley NL, Montgomery MK, Turner N Abstract Mitochondria play a critical role in energy production, cell signalling and cell survival. Defects in mitochondrial function...
01:48
Related Articles KCNK5 channels mostly expressed in cochlear outer sulcus cells are indispensable for hearing. Nat Commun. 2015;6:8780 Authors: Cazals Y, Bévengut M, Zanella S, Brocard F, Barhanin J, Gestreau C Abstract In the cochlea, K(+) is essential for mechano-electrical transduction....
Structural Insights into Ring Formation of Cohesin and Related Smc Complexes
Alexandros G. SfakianakisστοCell and Tissue Research by Alexandros G. SfakianakisΠριν από 30 δευτερόλεπτα
Publication date: Available online 28 April 2016 *Source:*Trends in Cell Biology Author(s): Thomas Gligoris, Jan Löwe Cohesin facilitates sister chromatid cohesion through the formation of a large ring structure that encircles DNA. Its function relies on two structural maintenance of chromosomes (Smc) proteins, which are found in almost all organisms tested, from bacteria to humans. In accordance with their ubiquity, Smc complexes, such as cohesin, condensin, Smc5-6, and the dosage compensation complex, affect almost all processes of DNA homeostasis. Although their precise molecular...περισσότερα »
Unravelling the Actin Cytoskeleton: A New Competitive Edge?
Alexandros G. SfakianakisστοCell and Tissue Research by Alexandros G. SfakianakisΠριν από 30 δευτερόλεπτα
Publication date: Available online 25 April 2016 *Source:*Trends in Cell Biology Author(s): Andrew J. Davidson, Will Wood Dynamic rearrangements in the actin cytoskeleton underlie a wide range of cell behaviours, which in turn contribute to many aspects of human health including embryogenesis, cancer metastasis, wound healing, and inflammation. Precise control of the actin cytoskeleton requires the coordinated activity of a diverse set of different actin regulators. However, our current understanding of the actin cytoskeleton has focused on how individual actin regulatory pathways f... περισσότερα »
Jacopo Meldolesi: Redefining Extracellular Vesicles
Alexandros G. SfakianakisστοCell and Tissue Research by Alexandros G. SfakianakisΠριν από 30 δευτερόλεπτα
[image: alertIcon.gif] Publication date: Available online 25 April 2016 *Source:*Trends in Cell Biology from Cell via ola Kala on Inoreader http://ift.tt/1seVgcB via IFTTT
Surgical treatment of osteonecrosis of the jaw with the use of platelet-rich fibrin: a prospective study of 15 patients
sfakianakismedicsστοORL ALLERGY AESTHETICS ANATOMY Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 39 δευτερόλεπτα
Publication date: Available online 11 May 2016 Source:International Journal of Oral and Maxillofacial Surgery Author(s): S.E. Nørholt, J. Hartlev The objective of this study was to evaluate the outcome of the surgical treatment of osteonecrosis of the jaw (ONJ) with the additional use of autologous membranes of platelet-rich fibrin (PRF). The study population consisted of […]
Surgical treatment of osteonecrosis of the jaw with the use of platelet-rich fibrin: a prospective study of 15 patients
Alexandros G. SfakianakisστοΚοσμητική ΟδοντοΙατρική και ΓναθοΧειρουργικήΠριν από 45 δευτερόλεπτα
[image: alertIcon.gif] Publication date: Available online 11 May 2016 *Source:*International Journal of Oral and Maxillofacial Surgery Author(s): S.E. Nørholt, J. Hartlev The objective of this study was to evaluate the outcome of the surgical treatment of osteonecrosis of the jaw (ONJ) with the additional use of autologous membranes of platelet-rich fibrin (PRF). The study population consisted of 15 patients with ONJ lesions in the maxilla (n=3), mandible (n=11), or both (n=1). Eight patients had malignant disease and were treated with high-dose anti-resorptive medication; seven were... περισσότερα »
The Association Between Olfaction and Depression: A Systematic Review
Alexandros G. SfakianakisστοΓεύση και ΌσφρησηΠριν από 47 δευτερόλεπτα
Previous studies on the relationship between olfaction and depression have revealed mixed results. In addition, few have focused on the reciprocity of this association. The aim of this study is to combine depression and olfactory data in two separate patient populations to further understand their association. A systematic literature review was conducted using 3 online databases to identify studies correlating olfaction and depression in patients presenting with either primary depression or primary olfactory dysfunction. For the depressed population, weighted means and standard de... περισσότερα »
Intramodal Olfactory Priming of Positive and Negative Odors in Humans Using Respiration-Triggered Olfactory Stimulation (RETROS)
Alexandros G. SfakianakisστοΓεύση και ΌσφρησηΠριν από 47 δευτερόλεπτα
Priming describes the principle of modified stimulus perception that occurs due to a previously presented stimulus. Although we have begun to understand the mechanisms of crossmodal priming, the concept of intramodal olfactory priming remains relatively unexplored. Therefore, we applied positive and negative odors using respiration-triggered olfactory stimulation (RETROS), enabling us to record the skin conductance response (SCR) and breathing data without a crossmodal cueing error and measure reaction times (RTs) for olfactory tasks. RT, SCR, and breathing data revealed that nega... περισσότερα »
The Association Between Olfaction and Depression: A Systematic Review
Αλέξανδρος ΣφακιανάκηςστοChemical Senses by Alexandros G. SfakianakisΠριν από 47 δευτερόλεπτα
Previous studies on the relationship between olfaction and depression have revealed mixed results. In addition, few have focused on the reciprocity of this association. The aim of this study is to combine depression and olfactory data in two separate patient populations to further understand their association. A systematic literature review was conducted using 3 online databases to identify studies correlating olfaction and depression in patients presenting with either primary depression or primary olfactory dysfunction. For the depressed population, weighted means and standard de... περισσότερα »
Intramodal Olfactory Priming of Positive and Negative Odors in Humans Using Respiration-Triggered Olfactory Stimulation (RETROS)
Αλέξανδρος ΣφακιανάκηςστοChemical Senses by Alexandros G. SfakianakisΠριν από 47 δευτερόλεπτα
Priming describes the principle of modified stimulus perception that occurs due to a previously presented stimulus. Although we have begun to understand the mechanisms of crossmodal priming, the concept of intramodal olfactory priming remains relatively unexplored. Therefore, we applied positive and negative odors using respiration-triggered olfactory stimulation (RETROS), enabling us to record the skin conductance response (SCR) and breathing data without a crossmodal cueing error and measure reaction times (RTs) for olfactory tasks. RT, SCR, and breathing data revealed that nega... περισσότερα »
Intraoperative delivery of cell-killing boost radiation - a review of current and future methods.
Alexandros G. SfakianakisστοHead and NeckΠριν από 50 δευτερόλεπτα
Related Articles *Intraoperative delivery of cell-killing boost radiation - a review of current and future methods.* Minim Invasive Ther Allied Technol. 2016 May 10;:1-12 Authors: Stoll A, van Oepen A, Friebe M Abstract Techniques for intraoperative radiation therapy (IORT), the applications of tumor bed radiation immediately after surgery or utilising intracavitary access, have evolved in recent years. They are designed to substitute or complement conventional external beam radiation therapy in selected patients. IORT has become an excellent treatment option because of good lon... περισσότερα »
Enhancement of bupivacaine caudal analgesia by using dexamethasone or clonidine in children undergoing subumbilical surgery
Alexandros G. SfakianakisστοAnaesthesiologyΠριν από 50 δευτερόλεπτα
*M Solanki Nilesh, R Engineer Smita, B Patel Rahul, K Vecham Pavan* Ain-Shams Journal of Anaesthesiology 2016 9(2):274-279 Background and aims Caudal analgesia produces profound intraoperative, as well as postoperative analgesia, with minimal psychological alteration in children. Because of its short duration, various additives have been used to prolong the duration of analgesia. The present study aimed to evaluate the effect of adding dexamethasone and clonidine to bupivacaine in caudal analgesia for children undergoing subumbilical surgeries. Patients and methods We conducted a pr...περισσότερα »
Terlipressin versus adrenaline in refractory septic shock
Alexandros G. SfakianakisστοAnaesthesiologyΠριν από 50 δευτερόλεπτα
*Heba A Labib, Niven G Fahmy, Tamer Y Elie Hamawy* Ain-Shams Journal of Anaesthesiology 2016 9(2):186-193 Objective The aim of this study was to compare terlipressin versus adrenaline in refractory septic shock. Patients and methods In this interventional prospective randomized study, 80 patients between 18 and 60 years of age who presented with refractory septic shock were enrolled. The patients were divided randomly into two groups of 40 patients each. Group A patients were treated with adrenaline and group T patients were treated with terlipressin. The goals of the therapy were t... περισσότερα »
Shoulder block versus interscalene block for postoperative pain relief after shoulder arthroscopy
Alexandros G. SfakianakisστοAnaesthesiologyΠριν από 50 δευτερόλεπτα
*Hala E Zanfaly, Amani A Aly* Ain-Shams Journal of Anaesthesiology 2016 9(2):296-303 Background Adequate pain control allows early rehabilitation and improves outcome after shoulder arthroscopic procedures. Objective The aim of this study was to compare the interscalene nerve block (ISB) with shoulder block (ShB) (suprascapular and axillary nerve blocks) for postoperative pain relief after arthroscopic shoulder surgery. Design This was a prospective, randomized, comparative study. Patients and methods A total of 75 patients of ASA grade I or II scheduled for shoulder arthroscopic su... περισσότερα »
Effect of recombinant growth hormone on immune response in pediatric burn patients
Alexandros G. SfakianakisστοAnaesthesiologyΠριν από 50 δευτερόλεπτα
*Yasser A Salem, Rania Hassan, Dalia M Elfawy, Neveen Girgis* Ain-Shams Journal of Anaesthesiology 2016 9(2):194-200 Background Management of severely burnt children is one of the most challenging situations in the ICU. Control of the hypercatabolic state is the most limiting step that determines patient survival. Immunocompromisation and delayed wound healing usually result in severe sepsis, which is the most common direct cause of death in these patients. There is debate about the efficacy and safety of recombinant human growth hormone (rGH), although it has been used to improve h...περισσότερα »
Intrathecal ketamine as an adjuvant in day-case surgeries: Comments
Alexandros G. SfakianakisστοAnaesthesiologyΠριν από 50 δευτερόλεπτα
*Mohd Saif Khan* Ain-Shams Journal of Anaesthesiology 2016 9(2):314-315 from Anaesthesia via ola Kala on Inoreader http://ift.tt/1sf0Vzv via IFTTT
The Association Between Olfaction and Depression: A Systematic Review
Alexandros G. SfakianakisστοΓεύση και ΌσφρησηΠριν από 59 δευτερόλεπτα
Previous studies on the relationship between olfaction and depression have revealed mixed results. In addition, few have focused on the reciprocity of this association. The aim of this study is to combine depression and olfactory data in two separate patient populations to further understand their association. A systematic literature review was conducted using 3 online databases to identify studies correlating olfaction and depression in patients presenting with either primary depression or primary olfactory dysfunction. For the depressed population, weighted means and standard de... περισσότερα »
Intramodal Olfactory Priming of Positive and Negative Odors in Humans Using Respiration-Triggered Olfactory Stimulation (RETROS)
Alexandros G. SfakianakisστοΓεύση και ΌσφρησηΠριν από 59 δευτερόλεπτα
Priming describes the principle of modified stimulus perception that occurs due to a previously presented stimulus. Although we have begun to understand the mechanisms of crossmodal priming, the concept of intramodal olfactory priming remains relatively unexplored. Therefore, we applied positive and negative odors using respiration-triggered olfactory stimulation (RETROS), enabling us to record the skin conductance response (SCR) and breathing data without a crossmodal cueing error and measure reaction times (RTs) for olfactory tasks. RT, SCR, and breathing data revealed that nega... περισσότερα »
Acute ethanol effects on neural encoding of reward size and delay in the nucleus accumbens
AlexAndros SfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026Πριν από 1 ώρα
Acute ethanol administration can cause impulsivity, resulting in increased preference for immediately available rewards over delayed but more valuable alternatives. The manner in which reward size and delay are represented in neural firing are not fully understood, and very little is known about ethanol effects on this encoding. To address this issue, we used in vivo electrophysiology to characterize neural firing in the core of the nucleus accumbens (NAcc) in rats responding for rewards that varied in size or delay after vehicle or ethanol administration. The NAcc is a central el... περισσότερα »
Peri-implant and periodontal microbiome diversity in aggressive periodontitis patients: a pilot study
Alexandros G. SfakianakisστοOroFacial Medicine by Alexandros G.SfakianakisΠριν από 1 ώρα
Abstract Aim To investigate the bacterial microbiome in periodontal and peri-implant biofilms deriving from aggressive periodontitis patients (AgP) in conditions of health and disease. Material and methods Ninety-one plaque samples were collected from 18 patients previously diagnosed and treated for AgP. The samples were taken from (i) 24 residual periodontal pockets (TD) (*n = *6 patients), (ii) 24 healthy periodontal sites (TH) (*n = *6 patients), (iii) 24 dental sites from the same implant patients (TM) (*n = *6 patients), (iv) 5 peri-implantitis sites (II) (*n = *2 patients), (... περισσότερα »
Intraoperative delivery of cell-killing boost radiation - a review of current and future methods.
Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
Related Articles *Intraoperative delivery of cell-killing boost radiation - a review of current and future methods.* Minim Invasive Ther Allied Technol. 2016 May 10;:1-12 Authors: Stoll A, van Oepen A, Friebe M Abstract Techniques for intraoperative radiation therapy (IORT), the applications of tumor bed radiation immediately after surgery or utilising intracavitary access, have evolved in recent years. They are designed to substitute or complement conventional external beam radiation therapy in selected patients. IORT has become an excellent treatment option because of good long... περισσότερα »
Trauma care OUS.
Αλέξανδρος ΣφακιανάκηςστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 1 ώρα
Trauma care Oslo Univerety Hospital: First stop E.R., next door it`s a "Hybrid room" (combined O.R. and diagnose room (so surgery can start,-and further diagnose- during life-saving surgery). CT next door. Simmilar set-up for Medical emergencys. Heliport 5 floors upp, dedicated elevator. ExEMTNor from EMS via xlomafota13 on Inoreader http://ift.tt/1Ojof8C
Intraoperative delivery of cell-killing boost radiation - a review of current and future methods.
Alexandros G. SfakianakisστοPubMed ORL Articles by Alexandros G.SfakianakisΠριν από 1 ώρα
Related Articles *Intraoperative delivery of cell-killing boost radiation - a review of current and future methods.* Minim Invasive Ther Allied Technol. 2016 May 10;:1-12 Authors: Stoll A, van Oepen A, Friebe M Abstract Techniques for intraoperative radiation therapy (IORT), the applications of tumor bed radiation immediately after surgery or utilising intracavitary access, have evolved in recent years. They are designed to substitute or complement conventional external beam radiation therapy in selected patients. IORT has become an excellent treatment option because of good lon... περισσότερα »
Review of “A Trial of Wound Irrigation in the Initial Management of Open Fracture Wounds” by the FLOW Investigators in N Engl J Med 373: 2629–2641, 2015
Alexandros G. SfakianakisστοΚοσμητική ΟδοντοΙατρική και ΓναθοΧειρουργικήΠριν από 1 ώρα
No abstract available from #ΓναθοΧειρουργική via xlomafota13 on Inoreader http://ift.tt/1TAt1ea via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
Patterns of Pediatric Maxillofacial Injuries
Alexandros G. SfakianakisστοΚοσμητική ΟδοντοΙατρική και ΓναθοΧειρουργικήΠριν από 1 ώρα
[image: image]Abstract: Facial trauma in children and adolescents is reported to range from 1% to 30%. Because of many anatomical, physiological, and psychological characteristics of the pediatric population, maxillofacial injuries in children should be treated with special consideration that is attributable to certain features inherent in facial growth patterns of children. This study evaluated maxillofacial injuries in 726 children in terms of incidence, patterns of injury, causes, and treatment modalities and compared these parameters among 3 pediatric age groups. Intergroup diff... περισσότερα »
Mumps Presenting as a Parotid Abscess
Alexandros G. SfakianakisστοΚοσμητική ΟδοντοΙατρική και ΓναθοΧειρουργικήΠριν από 1 ώρα
[image: image]Abstract: Parotid abscess is an uncommon condition in infants. It is frequently associated with prematurity, prolonged gavage feeding, and dehydration. Mumps is a viral disease caused by paramyxovirus. It frequently involves the parotid gland and is only rarely found in the pancreas, testis, or brain. The authors describe a rare case of a 10-month-old infant with mumps who developed the classical manifestations of unilateral acute parotitis progressing to formation of a parotid abscess that responded to 2 rounds of surgical drainage and antibiotic therapy. from #ΓναθοΧ... περισσότερα »
Metopic Craniosynostosis: A Demographic Analysis Outside an Urban Environment
Alexandros G. SfakianakisστοΚοσμητική ΟδοντοΙατρική και ΓναθοΧειρουργικήΠριν από 1 ώρα
[image: image]Background: Metopic craniosynostosis has traditionally been cited as the third most common type of isolated synostosis, after sagittal and coronal craniosynostosis. Recently, several urban institutions have observed an increase in the incidence of metopic synostosis. The authors sought to determine if similar demographic changes have occurred in a more suburban setting and if so, what specific variables were associated with this change. Methods: Patients who underwent operative correction of craniosynostosis between 1989 and 2014 were retrospectively reviewed. The type...περισσότερα »
Simultaneous Retrieval of Root Fragment, Sinus Lifting With Particulated Bone Graft, and Immediate Dental Implant Insertion
Alexandros G. SfakianakisστοΚοσμητική ΟδοντοΙατρική και ΓναθοΧειρουργικήΠριν από 1 ώρα
[image: image]Abstract: The aim of these 3 patient reports is to demonstrate a new technique for the reconstruction of the posterior maxilla in patient of a displaced root fragment. The retrieval of root fragments, sinus floor augmentation procedures with a particulated graft, and an implant insertion were performed in the same operation. A simultaneous oro-antral communication was also repaired in 2 patients. Sinus membrane elevations and retrieval of a root fragment via the lateral wall sinus approach were also performed. After repairing a membrane perforation with a particulated ... περισσότερα »
Epinephrine Injection in Greater Palatine Canal: An Alternative Technique for Reducing Hemorrhage During Septoplasty
Alexandros G. SfakianakisστοΚοσμητική ΟδοντοΙατρική και ΓναθοΧειρουργικήΠριν από 1 ώρα
[image: image]Objective: Obtaining adequate hemostasis during otolaryngology operations is necessary because a small amount of blood can be problematic and obscure the visual field. The authors aimed to compare the efficacy of combined greater palatine canal (GPC) and transnasal injection of lidocaine + epinephrine to transnasal injection alone in patients who underwent septoplasty. Methods: Patients with nasal septum deviation who were eligible for surgical correction of deviations were enrolled. Transnasal injections of 2 mL of 1% lidocaine + epinephrine 1:100,000 were performed i... περισσότερα »
Celsr3 and Fzd3 Organize a Pioneer Neuron Scaffold to Steer Growing Thalamocortical Axons
Alexandros G. SfakianakisστοΝευρολογία κ' ΝευροχειρουργικήΠριν από 1 ώρα
Celsr3 and Fzd3 regulate the development of reciprocal thalamocortical projections independently of their expression in cortical or thalamic neurons. To understand this cell non autonomous mechanism further, we tested whether Celsr3 and Fzd3 could act via Isl1-positive guidepost cells. Isl1-positive cells appear in the forebrain at embryonic day (E) 9.5-E10.5 and, from E12.5, they form 2 contingents in ventral telencephalon and prethalamus. In control mice, corticothalamic axons run in the ventral telencephalic corridor in close contact with Isl1-positive cells. When *Celsr3* or *... περισσότερα »
Spectral Signatures of Feedforward and Recurrent Circuitry in Monkey Area MT
Alexandros G. SfakianakisστοΝευρολογία κ' ΝευροχειρουργικήΠριν από 1 ώρα
Recordings of local field potential (LFP) in the visual cortex can show rhythmic activity at gamma frequencies (30–100 Hz). While the gamma rhythms in the primary visual cortex have been well studied, the structural and functional characteristics of gamma rhythms in extrastriate visual cortex are less clear. Here, we studied the spatial distribution and functional specificity of gamma rhythms in extrastriate middle temporal (MT) area of visual cortex in marmoset monkeys. We found that moving gratings induced narrowband gamma rhythms across cortical layers that were coherent across ... περισσότερα »
The role of expected reward in frontal eye field during natural scene search
Alexandros G. SfakianakisστοPhysiology by Alexandros G.SfakianakisΠριν από 1 ώρα
When a saccade is expected to result in a reward, both neural activity in oculomotor areas and the saccade itself (e.g. its vigor and latency) are altered (compared to when no reward is expected). As such, it is unclear whether the correlations of neural activity with reward indicate a representation of reward beyond a movement representation; the modulated neural activity may simply represent the differences in motor output due to expected reward. Here, to distinguish between these possibilities, we trained monkeys to perform a natural scene search task while we recorded from the... περισσότερα »
Shared and Distinct Retinal Input to the Mouse Superior Colliculus and Dorsal Lateral Geniculate Nucleus
Alexandros G. SfakianakisστοPhysiology by Alexandros G.SfakianakisΠριν από 1 ώρα
The mammalian retina conveys the vast majority of information about visual stimuli to two brain regions: the dorsal lateral geniculate nucleus (dLGN) and the superior colliculus (SC). The degree to which retinal ganglion cells (RGCs) send similar or distinct information to the two areas remains unclear despite the important constraints that different patterns of RGC input place on downstream visual processing. To resolve this ambiguity we injected a glycoprotein-deficient rabies virus coding for the expression of a fluorescent protein into the dLGN or SC; rabies virus labeled a sma... περισσότερα »
Temporal dynamics of visual category representation in the macaque inferior temporal cortex
Alexandros G. SfakianakisστοPhysiology by Alexandros G.SfakianakisΠριν από 1 ώρα
Object categories are recognized at multiple levels of hierarchical abstractions. Psychophysical studies have shown a more rapid perceptual access to the mid level category information (e.g. human faces) than the higher (superordinate; e.g. animal) or the lower (subordinate; e.g. face identity) levels. Mid level category members share many features while few features are shared between members of different mid level categories. To better understand the neural basis of expedited access to mid level category information we examined neural responses of the inferior temporal (IT) cort... περισσότερα »
Recording extracellular neural activity in the behaving monkey using a semi-chronic and high-density electrode system
Alexandros G. SfakianakisστοPhysiology by Alexandros G.SfakianakisΠριν από 1 ώρα
We describe a technique to semi-chronically record the cortical extracellular neural activity in the behaving monkey employing commercial high-density electrodes. After the design and construction of low cost microdrives that allows varying the depth of the recording locations after the implantation surgery, we recorded the extracellular unit activity from pools of neurons at different depths in the presupplementary motor cortex (pre-SMA) of a Rhesus monkey trained in a synchronization-tapping task. The collected data was processed to classify cells as putative pyramidal cells or ...περισσότερα »
Motor learning and cross-limb transfer rely upon distinct neural adaptation processes
Alexandros G. SfakianakisστοPhysiology by Alexandros G.SfakianakisΠριν από 1 ώρα
Performance benefits conferred in the untrained limb after unilateral motor practice are termed cross-limb transfer. Although the effect is robust, the neural mechanisms remain incompletely understood. Here we use non-invasive brain stimulation to reveal that the neural adaptations that mediate motor learning in the trained limb are distinct from those that underlie cross-limb transfer to the opposite limb. Thirty-six participants practiced a ballistic motor task with their right index finger (150 trials), followed by intermittent-theta burst stimulation (iTBS) applied to the train... περισσότερα »
Pathophysiology of Affective Disorders: Functional Interaction of Stress Hormones and Hippocampal Excitation
Alexandros G. SfakianakisστοPhysiology by Alexandros G.SfakianakisΠριν από 1 ώρα
An important new study by Kvarta and colleagues (J Neurophysiol 114: 1713-1724, 2015) examined the effects of persistent stress and excessive glucocorticoid levels on hippocampal function and emotional behavior in rodents. The authors specifically implicate the temporoammonic pathway as being susceptible to reductions in excitatory function in the context of chronic stress. We discuss the importance of this new finding in the broader context of medication development for major depressive disorder (MDD). from Physiology via xlomafota13 on Inoreader http://ift.tt/1X2qRsZ
Dependence of auditory spatial updating on vestibular, proprioceptive, and efference copy signals
Alexandros G. SfakianakisστοPhysiology by Alexandros G.SfakianakisΠριν από 1 ώρα
Humans localize sounds by comparing inputs across the two ears, resulting in a head-centered representation of sound-source position. When the head moves, information about head movement must be combined with the head-centered estimate to correctly update the world-centered sound-source position. Spatial updating has been extensively studied in the visual system, but less is known about how head movement signals interact with binaural information during auditory spatial updating. In the current experiments, listeners compared the world-centered azimuthal position of two sound sour...περισσότερα »
Acute ethanol effects on neural encoding of reward size and delay in the nucleus accumbens
Alexandros G. SfakianakisστοPhysiology by Alexandros G.SfakianakisΠριν από 1 ώρα
Acute ethanol administration can cause impulsivity, resulting in increased preference for immediately available rewards over delayed but more valuable alternatives. The manner in which reward size and delay are represented in neural firing are not fully understood, and very little is known about ethanol effects on this encoding. To address this issue, we used in vivo electrophysiology to characterize neural firing in the core of the nucleus accumbens (NAcc) in rats responding for rewards that varied in size or delay after vehicle or ethanol administration. The NAcc is a central el... περισσότερα »
Low dose intratympanic gentamicin for control of intractable vertigo
Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 1 ώρα
*H Gayathri, Sutrave Satyananda Rao* Indian Journal of Otology 2016 22(2):110-118 Background and Objectives: Intratympanic gentamicin therapy is an effective modality for control of vertigo in Meniere's disease (MD) and when given in low concentration (<30 mg/mL), once weekly minimizes its side effects like chronic vestibular insufficiency or hearing loss. We studied the efficacy of low dose interval intratympanic gentamicin therapy in control of intractable vertigo in MD and the postprocedure hearing loss. As gentamicin is vestibular end-organ selective and not specific for treatme...περισσότερα »
Methods to prevent water entering the ear: An ear cap
Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 1 ώρα
*Rajagopalan Raman* Indian Journal of Otology 2016 22(2):143-143 from #ORL via xlomafota13 on Inoreader http://ift.tt/1TAuKjH via IFTTT
Sleep disorders and chronic craniofacial pain: characteristics and management possibilities
Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 1 ώρα
Chronic craniofacial pain involves the head, face and oral cavity and is associated with significant morbidity and high levels of health care utilization. A bidirectional relationship is suggested in the literature for poor sleep and pain, and craniofacial pain and sleep are reciprocally related. We review this relationship and discuss management options.Part I review the relationship between pain and sleep disorders in the context of 4 diagnostic categories of chronic craniofacial pain: 1) Primary headaches: migraines, tension-type headache (TTH), trigeminal autonomic cephalalgias... περισσότερα »
Leiomyoma of External Auditory Canal
Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 1 ώρα
Abstract This article reports a case of piloleiomyoma of external auditory canal, which is the 7th case of leiomyoma of the external auditory canal being reported and the 2nd case of leiomyoma arising from arrectores pilorum muscles, all the other five cases were angioleiomyomas, arising from blood vessels. A 52 years old male presented with a mass in the right external auditory canal and decreased hearing of 6 months duration. Tumor excision done by end aural approach. Histopathological examination report was leiomyoma. It is extremely rare for leiomyoma to occur in the external ...περισσότερα »
The Association Between Olfaction and Depression: A Systematic Review
Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 2 ώρες
Previous studies on the relationship between olfaction and depression have revealed mixed results. In addition, few have focused on the reciprocity of this association. The aim of this study is to combine depression and olfactory data in two separate patient populations to further understand their association. A systematic literature review was conducted using 3 online databases to identify studies correlating olfaction and depression in patients presenting with either primary depression or primary olfactory dysfunction. For the depressed population, weighted means and standard de... περισσότερα »
Intramodal Olfactory Priming of Positive and Negative Odors in Humans Using Respiration-Triggered Olfactory Stimulation (RETROS)
Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 2 ώρες
Priming describes the principle of modified stimulus perception that occurs due to a previously presented stimulus. Although we have begun to understand the mechanisms of crossmodal priming, the concept of intramodal olfactory priming remains relatively unexplored. Therefore, we applied positive and negative odors using respiration-triggered olfactory stimulation (RETROS), enabling us to record the skin conductance response (SCR) and breathing data without a crossmodal cueing error and measure reaction times (RTs) for olfactory tasks. RT, SCR, and breathing data revealed that nega... περισσότερα »
Intraoperative delivery of cell-killing boost radiation - a review of current and future methods.
Alexandros G. SfakianakisστοHead and NeckΠριν από 2 ώρες
Related Articles *Intraoperative delivery of cell-killing boost radiation - a review of current and future methods.* Minim Invasive Ther Allied Technol. 2016 May 10;:1-12 Authors: Stoll A, van Oepen A, Friebe M Abstract Techniques for intraoperative radiation therapy (IORT), the applications of tumor bed radiation immediately after surgery or utilising intracavitary access, have evolved in recent years. They are designed to substitute or complement conventional external beam radiation therapy in selected patients. IORT has become an excellent treatment option because of good lon... περισσότερα »
Aberrant Internal Carotid Artery: A Rare Cause of Dysphagia
Alexandros G. SfakianakisστοΚοσμητική ΟδοντοΙατρική και ΓναθοΧειρουργικήΠριν από 2 ώρες
[image: image]No abstract available from #ΓναθοΧειρουργική via xlomafota13 on Inoreader http://ift.tt/1T6ffE3 via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
Peri-implant and periodontal microbiome diversity in aggressive periodontitis patients: a pilot study
Alexandros G. SfakianakisστοΚοσμητική ΟδοντοΙατρική και ΓναθοΧειρουργικήΠριν από 2 ώρες
Abstract Aim To investigate the bacterial microbiome in periodontal and peri-implant biofilms deriving from aggressive periodontitis patients (AgP) in conditions of health and disease. Material and methods Ninety-one plaque samples were collected from 18 patients previously diagnosed and treated for AgP. The samples were taken from (i) 24 residual periodontal pockets (TD) (*n = *6 patients), (ii) 24 healthy periodontal sites (TH) (*n = *6 patients), (iii) 24 dental sites from the same implant patients (TM) (*n = *6 patients), (iv) 5 peri-implantitis sites (II) (*n = *2 patients)... περισσότερα »
Feasibility and Advantage of a Muscle-Sparing Laterally Based Pericranial Flap
Alexandros G. SfakianakisστοΚοσμητική ΟδοντοΙατρική και ΓναθοΧειρουργικήΠριν από 2 ώρες
[image: image]Background: For a safe and reliable middle skull base reconstruction, the temporalis muscle flaps or pericranial-temporalis muscle flaps have usually been used as the first-choice in clinical practice. But these flaps have an inevitable disadvantage, namely, temporal hollowing. To address this problem, in this study, the authors describe the feasibility and advantages of using a muscle-sparing laterally based pericranial flap. Method: The authors reviewed 19 patients who had undergone middle skull base reconstruction using laterally based pericranial flaps. There were ...περισσότερα »
Huge Frontal-Temporal Lobe Arachnoid Cyst Presenting as an Weariness Migraine
Alexandros G. SfakianakisστοΚοσμητική ΟδοντοΙατρική και ΓναθοΧειρουργικήΠριν από 2 ώρες
[image: image]Abstract: To the authors' knowledge, most of intracranial arachnoid cyst located in middle cranial fossa and lateral fissure cistern. So, huge frontal-temporal lobe arachnoid cyst is rare. Symptoms of arachnoid cyst may be atypical, including headache, nausea, vomiting, epilepsy, poor memory, and so on. Of course, migraine related to weariness is a rare benign headache disorder. The authors reported a patient presenting with weariness migraine associated with large frontal-temporal lobe arachnoid cyst. from #ΓναθοΧειρουργική via xlomafota13 on Inoreader http://ift.tt/1... περισσότερα »
Bone Regeneration of the Maxillofacial Region Through the Use of Mesenchymal Cells Obtained by a Filtration Process of the Adipose Tissue
Alexandros G. SfakianakisστοΚοσμητική ΟδοντοΙατρική και ΓναθοΧειρουργικήΠριν από 2 ώρες
[image: image]Abstract: In this work, the authors will discuss about a new protocol and rapid alternative to isolate the mesenchymal stromal cells from the stromal vascular fraction, without the use of collagenase, to regenerate the bone tissue in the maxillo-facial region. This method employs a device that allows the isolation and concentration of stromal vascular fraction by means of lipoaspirates, which separate the lipid component and fragments of the extracellular matrix. The innovative element consists in using a filtration device instead of a centrifuging device to separate t... περισσότερα »
Polyurethane Foam-Filled Skull Replica of Craniosynostosis for Surgical Training
Alexandros G. SfakianakisστοΚοσμητική ΟδοντοΙατρική και ΓναθοΧειρουργικήΠριν από 2 ώρες
[image: image]Abstract: Craniosynostosis has a relatively low incidence in the general population and its treatment requires cautious approaches. For these reasons, patients are usually referred to several specialists or a medical center. Therefore, most trainees and young surgeons do not have any chances to experience patients of craniosynostosis, but learn about it only from textbooks. And for a surgeon who tries to operate on a craniosynostosis patient, it is hard to make a proper preoperative plan. The authors suggest a polyurethane foam-filled skull replica of craniosynostosis ... περισσότερα »
Formation of lipid bodies and fatty acid composition changes upon pre-akinete formation in arctic and Antarctic Zygnema (Zygnematophyceae, Streptophyta) strains
Alexandros G. SfakianakisστοΛοίμωξηΠριν από 2 ώρες
Filamentous green algae of the genus *Zygnema* (Zygnematophyceae, Streptophyta) are key components of polar hydro-terrestrial mats where they face various stressors including UV irradiation, freezing, desiccation and osmotic stress. Their vegetative cells can develop into pre-akinetes, i.e., reserve-rich, mature cells. We investigated lipid accumulation and fatty acid (FA) composition upon pre-akinete formation in an arctic and an Antarctic *Zygnema* strain using transmission electron microscopy (TEM) and gas chromatography coupled with mass spectrometry (GC-MS). Pre-akinetes form...περισσότερα »
Changes in microbial communities associated with gas hydrates in subseafloor sediments from the Nankai Trough
Alexandros G. SfakianakisστοΛοίμωξηΠριν από 2 ώρες
Little is known about the microbial distribution patterns in subseafloor sediments. This study examines microbial diversity and activities in sediments of the Nankai Trough, where biogenic gas hydrates are deposited. Illumina sequencing of 16S rRNA genes revealed that the prokaryotic community structure is correlated with hydrate occurrence and depth but not with the sedimentary facies. The bacterial phyla 'Atribacteria' lineage JS1 and *Chloroflexi* dominated in all samples, whereas lower taxonomic units of *Chloroflexi* accounted for community variation related to hydrate satura... περισσότερα »
