Tumor Debulking in the Management of Laryngeal Cancer Airway Obstruction
Patients presenting with advanced aerodigestive malignancy and respiratory compromise often undergo tracheotomy as initial airway management. Tumor debulking is a potential alternative. We present a case series with chart review to communicate our institutional experience with this technique. T3/4 glottic and supraglottic cancers treated between 2004 and 2014 underwent review, and 14 patients were identified for this study. Of these, 5 (35.7%) required subsequent tracheotomy, and 9 (64.3%) did not. Patients requiring subsequent tracheotomy had a delay in initiating definitive trea... περισσότερα »
Gabapentin for Perioperative Analgesia in Otorhinolaryngology-Head and Neck Surgery: Systematic Review
Objective Recent research has investigated the role of gabapentin in perioperative pain relief in otorhinolaryngology–head and neck surgery. This review aims to identify whether sufficient evidence exists for the routine use of gabapentin in the perioperative setting. Data Sources MEDLINE, Cochrane CENTRAL, EMBASE, and Google Scholar. Review Methods A comprehensive systematic search was performed with keywords for articles up to November 2015. The systematic review included all randomized, placebo-, and active-controlled trials investigating the role of perioperative gabapenti... περισσότερα »
Tumor Debulking in the Management of Laryngeal Cancer Airway Obstruction
Patients presenting with advanced aerodigestive malignancy and respiratory compromise often undergo tracheotomy as initial airway management. Tumor debulking is a potential alternative. We present a case series with chart review to communicate our institutional experience with this technique. T3/4 glottic and supraglottic cancers treated between 2004 and 2014 underwent review, and 14 patients were identified for this study. Of these, 5 (35.7%) required subsequent tracheotomy, and 9 (64.3%) did not. Patients requiring subsequent tracheotomy had a delay in initiating definitive trea... περισσότερα »
Gabapentin for Perioperative Analgesia in Otorhinolaryngology-Head and Neck Surgery: Systematic Review
Objective Recent research has investigated the role of gabapentin in perioperative pain relief in otorhinolaryngology–head and neck surgery. This review aims to identify whether sufficient evidence exists for the routine use of gabapentin in the perioperative setting. Data Sources MEDLINE, Cochrane CENTRAL, EMBASE, and Google Scholar. Review Methods A comprehensive systematic search was performed with keywords for articles up to November 2015. The systematic review included all randomized, placebo-, and active-controlled trials investigating the role of perioperative gabapenti... περισσότερα »
Botulinum Toxin for Rhinitis
Abstract Purpose of Review Rhinitis is a common clinical entity. Besides nasal obstruction, itching, and sneezing, one of the most important symptoms of rhinitis is nasal hypersecretion produced by nasal glands and exudate from the nasal vascular bed. Allergic rhinitis is an IgE-mediated inflammatory reaction of nasal mucosa after exposure to environmental allergens. Idiopathic rhinitis describes rhinitis symptoms that occur after non-allergic, noninfectious irritants. Specific allergen avoidance, topical nasal decongestants, nasal corticosteroids, immunotherapy, and sinonasal surg... περισσότερα »
Selecting Appropriate Tests to Assess the Benefits of Bilateral Amplification With Hearing Aids
The aim of this study was to investigate the effect of bilateral hearing aids (HA) in subjects with mild and moderate-to-severe hearing loss. This study was designed as a within-subject feasibility study. Bilateral HA use was assessed using different laboratory tests on speech reception, listening effort, noise tolerance, and localization. All data were evaluated with bilateral and unilateral HA fittings. Forty experienced bilateral HA users were included with hearing impairment ranging from mild to moderate-to-severe. Subjects were stratified into two groups based on the degree o... περισσότερα »
Botulinum Toxin for Rhinitis
Abstract Purpose of Review Rhinitis is a common clinical entity. Besides nasal obstruction, itching, and sneezing, one of the most important symptoms of rhinitis is nasal hypersecretion produced by nasal glands and exudate from the nasal vascular bed. Allergic rhinitis is an IgE-mediated inflammatory reaction of nasal mucosa after exposure to environmental allergens. Idiopathic rhinitis describes rhinitis symptoms that occur after non-allergic, noninfectious irritants. Specific allergen avoidance, topical nasal decongestants, nasal corticosteroids, immunotherapy, and sinonasal surg... περισσότερα »
Short-stay hospital admission after free tissue transfer for head and neck reconstruction
[image: cover.gif?v=1&s=89c747938c409c8905c59b71] Objectives/Hypothesis To show that, for patients with few medical comorbidities and at low risk for airway compromise or fistula formation, early discharge after free tissue transfer for head and neck reconstruction is a safe and viable option. Study Design Retrospective chart review. Methods A cohort of patients who underwent free tissue transfer for head and neck reconstruction between February 2010 and December 2014 and who were discharged from the hospital by postoperative day 3 were reviewed. Results Fifty patients underg... περισσότερα »
Selecting Appropriate Tests to Assess the Benefits of Bilateral Amplification With Hearing Aids
The aim of this study was to investigate the effect of bilateral hearing aids (HA) in subjects with mild and moderate-to-severe hearing loss. This study was designed as a within-subject feasibility study. Bilateral HA use was assessed using different laboratory tests on speech reception, listening effort, noise tolerance, and localization. All data were evaluated with bilateral and unilateral HA fittings. Forty experienced bilateral HA users were included with hearing impairment ranging from mild to moderate-to-severe. Subjects were stratified into two groups based on the degree o... περισσότερα »
Short-stay hospital admission after free tissue transfer for head and neck reconstruction
[image: cover.gif?v=1&s=89c747938c409c8905c59b71] Objectives/Hypothesis To show that, for patients with few medical comorbidities and at low risk for airway compromise or fistula formation, early discharge after free tissue transfer for head and neck reconstruction is a safe and viable option. Study Design Retrospective chart review. Methods A cohort of patients who underwent free tissue transfer for head and neck reconstruction between February 2010 and December 2014 and who were discharged from the hospital by postoperative day 3 were reviewed. Results Fifty patients underg... περισσότερα »
Serum PAI-1 and PAI-1 4G/5G Polymorphism in Hepatitis C Virus-Induced Cirrhosis and Hepatitis C Virus-Induced Hepatocellular Carcinoma patients
Viral Immunology , Vol. 0, No. 0. from #ENT via xlomafota13 on Inoreader http://ift.tt/2acEsJz via IFTTT
Serum PAI-1 and PAI-1 4G/5G Polymorphism in Hepatitis C Virus-Induced Cirrhosis and Hepatitis C Virus-Induced Hepatocellular Carcinoma patients
Viral Immunology , Vol. 0, No. 0. from #ENT via xlomafota13 on Inoreader http://ift.tt/2acEsJz via IFTTT
Variations in pollen counts between Indianapolis, IN, and Dayton, OH, in spring 2013 and 2014
Publication date: Available online 25 July 2016 *Source:*Annals of Allergy, Asthma & Immunology Author(s): Girish Vitalpur, Shaylar Padgett, Kirsten M. Kloepfer, James Slaven, Frederick E. Leickly from #ENT via xlomafota13 on Inoreader http://ift.tt/2ady3kI via IFTTT
Successful cyclophosphamide desensitization in a pediatric patient with systemic lupus erythematosus and anaphylaxis after initial exposure
Publication date: Available online 26 July 2016 *Source:*Annals of Allergy, Asthma & Immunology Author(s): Yoomie J. Lee, Jennifer Toh, Elina Jerschow, Jenny Shliozberg from #ENT via xlomafota13 on Inoreader http://ift.tt/2acBWDb via IFTTT
Variations in pollen counts between Indianapolis, IN, and Dayton, OH, in spring 2013 and 2014
Publication date: Available online 25 July 2016 *Source:*Annals of Allergy, Asthma & Immunology Author(s): Girish Vitalpur, Shaylar Padgett, Kirsten M. Kloepfer, James Slaven, Frederick E. Leickly from #ENT via xlomafota13 on Inoreader http://ift.tt/2ady3kI via IFTTT
Successful cyclophosphamide desensitization in a pediatric patient with systemic lupus erythematosus and anaphylaxis after initial exposure
Publication date: Available online 26 July 2016 *Source:*Annals of Allergy, Asthma & Immunology Author(s): Yoomie J. Lee, Jennifer Toh, Elina Jerschow, Jenny Shliozberg from #ENT via xlomafota13 on Inoreader http://ift.tt/2acBWDb via IFTTT
Comparative Study of Apo-Cetirizine Single Therapy and Intermittent Sequential Therapy with Cetirizine, Loratadine and Chlorpheniramine in Allergic Rhinitis
Abstract There are limited numbers of articles, studying combined use of antihistamines. In this study, we compare single therapy of Apo-Cetirizine with a new regimen of intermittent sequential therapy with cetirizine, loratadine and chlorpheniramine in treatment of seasonal allergic rhinitis. This randomized clinical trial was performed between April and September at the peak prevalence of seasonal allergic rhinitis. Fifty-four eligible patients diagnosed clinically to have seasonal allergic rhinitis were randomized in two groups: 24 cases in single therapy arm, received Apo-Ceti... περισσότερα »
Functional Endoscopic Sinus Surgery Versus Balloon Sinuplasty with Ethmoidectomy: A 2-year Analysis in Pediatric Chronic Rhinosinusitis
Abstract To evaluate the 2-year post-operative outcomes of pediatric patients with chronic rhinosinusitis (CRS) treated with balloon catheter sinuplasty (BCS) and ethmoidectomy compared to functional endoscopic sinus surgery (FESS). Two-group, retrospective cohort study of 28 children with CRS was performed. Of these 28 participants, 15 were treated with traditional FESS (53.6 %) and 13 (46.4 %) underwent traditional ethmoidectomy with balloon sinuplasty. Pre-operative and 2-year postoperative total symptom scores and medications were compared. To examine the potential long-term di... περισσότερα »
Lack of Association between Missense Variants in GRHL3 (rs2486668 and rs545809) and Susceptibility to Non-Syndromic Orofacial Clefts in a Han Chinese Population
by Miao He, Zhuan Bian Background Grainyhead-like-3 (*GRHL3*) was recently identified as the second gene that, when mutated, can leads to Van der Woude syndrome, which is characterized by orofacial clefts (OFC) and lower lip pits. In addition, a missense variant (rs41268753) in *GRHL3* confers risk for non-syndromic cleft palate cases of European ancestry. Together with interferon regulatory factor 6 (*IRF6*), *GRHL3* may be associated with the risk of NSOFC which awaits for being verified across different ethnic populations. Objective The aim of this study was to investigate th... περισσότερα »
Comparative Study of Apo-Cetirizine Single Therapy and Intermittent Sequential Therapy with Cetirizine, Loratadine and Chlorpheniramine in Allergic Rhinitis
Abstract There are limited numbers of articles, studying combined use of antihistamines. In this study, we compare single therapy of Apo-Cetirizine with a new regimen of intermittent sequential therapy with cetirizine, loratadine and chlorpheniramine in treatment of seasonal allergic rhinitis. This randomized clinical trial was performed between April and September at the peak prevalence of seasonal allergic rhinitis. Fifty-four eligible patients diagnosed clinically to have seasonal allergic rhinitis were randomized in two groups: 24 cases in single therapy arm, received Apo-Ceti... περισσότερα »
Telemedicine for Trauma and Emergency: the eICU
Telemedicine for Trauma and Emergency: the eICU: Abstract Purpose of Review The purpose of this study was to describe the current use of telemedicine in the intensive care units (ICUs), particularly as it relates to trauma and emergency. Recent Findings Telemedicine in the ICU has been validated through several large before-after studies with positive effects… Continue reading Telemedicine for Trauma and Emergency: the eICU
Woman With Dyspnea and Abdominal Rash
Woman With Dyspnea and Abdominal Rash: A 61-year-old Jamaican woman presented with dyspnea and abdominal rash for 2 days, preceded by abdominal pain and vomiting for 2 weeks. She was hypoxic and hypotensive, requiring ventilator and vasopressor support. Computed tomography (CT) of chest, abdomen, and pelvis revealed diffuse ground-glass opacities with patchy infiltrates in the… Continue reading Woman With Dyspnea and Abdominal Rash
Pituitary Dysfunction: A Case Series of Immune Checkpoint Inhibitor–Related Hypophysitis in an Emergency Department
Pituitary Dysfunction: A Case Series of Immune Checkpoint Inhibitor–Related Hypophysitis in an Emergency Department: The development of an anticytotoxic T-lymphocyte antigen-4 antibody1 marked the beginning of a new class of drugs, immune checkpoint inhibitors, which have been found to improve survival in certain types of cancer. Ipilimumab (Yervoy) is the first immune checkpoint inhibitor to… Continue reading Pituitary Dysfunction: A Case Series of Immune Checkpoint Inhibitor–Related Hypophysitis in an Emergency Department
Not All Coughs Are Asthma or Allergies: Churg–Strauss Syndrome
Not All Coughs Are Asthma or Allergies: Churg–Strauss Syndrome: Cardiomyopathy in patients with Churg–Strauss syndrome (CSS) carries a poor prognosis, with a high 5-year mortality rate, and requires treatment with immunosuppressive therapy. There is no single pathognomonic test or clinical finding for diagnosing CSS; instead, it is based upon meeting four of six criteria. Ani… Continue reading Not All Coughs Are Asthma or Allergies: Churg–Strauss Syndrome
Clinical feasibility of interstitial brachytherapy using a “hybrid” applicator combining uterine tandem and interstitial metal needles based on CT for locally advanced cervical cancer
Publication date: Available online 26 July 2016 Source:Brachytherapy Author(s): Zhong-Shan Liu, Jie Guo, Xia Lin, Hong-Yong Wang, Ling Qiu, Xiao-Jun Ren, Yun-Feng Li, Bing-Ya Zhang, Tie-Jun Wang PurposeTo explore the dosimetric advantage of target volume and surrounding normal tissue by using interstitial (IS) brachytherapy (BT) based on three-dimensional CT in locally advanced cervical cancer, as… Continue reading Clinical feasibility of interstitial brachytherapy using a “hybrid” applicator combining uterine tandem and interstitial metal needles based on CT for locally advanced ce... περισσότερα »
Gabapentin for Perioperative Analgesia in Otorhinolaryngology-Head and Neck Surgery: Systematic Review
Objective Recent research has investigated the role of gabapentin in perioperative pain relief in otorhinolaryngology–head and neck surgery. This review aims to identify whether sufficient evidence exists for the routine use of gabapentin in the perioperative setting. Data Sources MEDLINE, Cochrane CENTRAL, EMBASE, and Google Scholar. Review Methods A comprehensive systematic search was performed with… Continue reading Gabapentin for Perioperative Analgesia in Otorhinolaryngology-Head and Neck Surgery: Systematic Review
Patterns of weight change after the diagnosis of type 2 diabetes in Scotland and their relationship with glycaemic control, mortality and cardiovascular outcomes: a retrospective cohort study
Objectives To determine weight change patterns in Scottish patients 2 years after diagnosis of type 2 diabetes and to examine these in association with medium-term glycaemic, mortality and cardiovascular outcomes. Setting Using a retrospective cohort design, ethical approval was obtained to link the Scottish diabetes care database to hospital admission and mortality records. Participants 29… Continue reading Patterns of weight change after the diagnosis of type 2 diabetes in Scotland and their relationship with glycaemic control, mortality and cardiovascular outcomes: a retrospective... περισσότερα »
Hearing and vision screening tools for long-term care residents with dementia: protocol for a scoping review
Introduction Hearing and vision loss among long-term care (LTC) residents with dementia frequently goes unnoticed and untreated. Despite negative consequences for these residents, there is little information available about their sensory abilities and care assessments and practices seldom take these abilities or accessibility needs into account. Without adequate knowledge regarding such sensory loss, it is… Continue reading Hearing and vision screening tools for long-term care residents with dementia: protocol for a scoping review
SCISSOR–Spinal Cord Injury Study on Small molecule-derived Rho inhibition: a clinical study protocol
Introduction The approved analgesic and anti-inflammatory drugs ibuprofen and indometacin block the small GTPase RhoA, a key enzyme that impedes axonal sprouting after axonal damage. Inhibition of the Rho pathway in a central nervous system-effective manner requires higher dosages compared with orthodox cyclooxygenase-blocking effects. Preclinical studies on spinal cord injury (SCI) imply improved motor recovery… Continue reading SCISSOR–Spinal Cord Injury Study on Small molecule-derived Rho inhibition: a clinical study protocol
Protocol for study of financial incentives for smoking cessation in pregnancy (FISCP): randomised, multicentre study
Introduction Maternal smoking during pregnancy is associated with adverse perinatal and postnatal health outcomes. The efficacy of nicotine replacement therapies in helping pregnant smokers to quit is not clearly demonstrated; therefore new interventions should be proposed and assessed. Financial incentives rewarding abstinence from tobacco smoking is one of the promising options. Objective To assess the… Continue reading Protocol for study of financial incentives for smoking cessation in pregnancy (FISCP): randomised, multicentre study
Colorectal Cancer Subtypes by immunohistochemistry
Purpose: Recent transcriptomic analyses have identified four distinct molecular subtypes of colorectal cancer (CRC) with evident clinical relevance. However, the requirement for sufficient quantities of bulk tumor and difficulties in obtaining high quality genome-wide transcriptome data from formalin-fixed paraffin-embedded tissue are obstacles towards widespread adoption of this taxonomy. Here, we develop an immunohistochemistry-based classifier to… Continue reading Colorectal Cancer Subtypes by immunohistochemistry
Colorectal Cancer Subtypes by immunohistochemistry
Purpose: Recent transcriptomic analyses have identified four distinct molecular subtypes of colorectal cancer (CRC) with evident clinical relevance. However, the requirement for sufficient quantities of bulk tumor and difficulties in obtaining high quality genome-wide transcriptome data from formalin-fixed paraffin-embedded tissue are obstacles towards widespread adoption of this taxonomy. Here, we develop an immunohistochemistry-based classifier to… Continue reading Colorectal Cancer Subtypes by immunohistochemistry
Pheochromocytoma and Paraganglioma in Patients with Neurofibromatosis Type 1
Abstract Objective Individuals with neurofibromatosis type 1 (NF1) are at an increased risk of developing a pheochromocytoma or paraganglioma (PHEO/PGL). However the best case detection strategy is unknown. Our objectives were to describe the prevalence, clinical presentation and outcomes of PHEO/PGL associated with NF1, and formulate case detection testing recommendations for PHEO/PGL. Design A retrospective… Continue reading Pheochromocytoma and Paraganglioma in Patients with Neurofibromatosis Type 1
Selecting Appropriate Tests to Assess the Benefits of Bilateral Amplification With Hearing Aids
The aim of this study was to investigate the effect of bilateral hearing aids (HA) in subjects with mild and moderate-to-severe hearing loss. This study was designed as a within-subject feasibility study. Bilateral HA use was assessed using different laboratory tests on speech reception, listening effort, noise tolerance, and localization. All data were evaluated with… Continue reading Selecting Appropriate Tests to Assess the Benefits of Bilateral Amplification With Hearing Aids
Rumination, Excessive Reassurance Seeking, and Stress Generation Among Early Adolescent Girls
Nolen-Hoeksema proposed that rumination increases stressful events and circumstances; however, few studies have examined this question. Thus, we explored whether (a) rumination predicted increases in the generation of chronic and acute stress, (b) excessive reassurance seeking (ERS) mediated links between rumination and stress generation, (c) rumination increased exposure to acute independent (uncontrollable) stress, and (d)… Continue reading Rumination, Excessive Reassurance Seeking, and Stress Generation Among Early Adolescent Girls
Variations in pollen counts between Indianapolis, IN, and Dayton, OH, in spring 2013 and 2014
Publication date: Available online 25 July 2016 Source:Annals of Allergy, Asthma & Immunology Author(s): Girish Vitalpur, Shaylar Padgett, Kirsten M. Kloepfer, James Slaven, Frederick E. Leickly from Allergy and Immunology via xlomafota13 on Inoreader http://ift.tt/2ady3kI from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/2a8lEgI via IFTTT
Successful cyclophosphamide desensitization in a pediatric patient with systemic lupus erythematosus and anaphylaxis after initial exposure
Publication date: Available online 26 July 2016 Source:Annals of Allergy, Asthma & Immunology Author(s): Yoomie J. Lee, Jennifer Toh, Elina Jerschow, Jenny Shliozberg from Allergy and Immunology via xlomafota13 on Inoreader http://ift.tt/2acBWDb from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/2avAcdO via IFTTT
Physicochemical and catalytic properties of NAD + – dependent malate dehydrogenase isoforms from maize mesophyll
Abstract Malate dehyrogenase isoforms (46- and 70-fold purifications) with specific activities of the 640 and 990 U/mg protein were obtained in an electrophoretically homogeneous state from maize mesophyll. The physicochemical and catalytic properties of these isoforms were studied. The molecular weight and the Michaelis constants were determined; the effect of hydrogen ions on the forward… Continue reading Physicochemical and catalytic properties of NAD + – dependent malate dehydrogenase isoforms from maize mesophyll
Neutralization of anticoagulant activity of heparin by N-(2-hydroxy-3-trimethylammonium) propyl chloride derivatives of chitosan
Abstract Alkylated derivatives of low molecular weight chitosan with different substitution degrees of 98, 40, and 9% (I, II, and III respectively) have been synthesized. The structure of the obtained derivatives was defined by spectral assays (IR-spectroscopy and proton magnetic resonance). Chitosan derivatives were characterized with positive zeta-potential (33–51 mV) and solubility from 2 to… Continue reading Neutralization of anticoagulant activity of heparin by N-(2-hydroxy-3-trimethylammonium) propyl chloride derivatives of chitosan
Insight into a novel β-1,4-glucosidase from Streptomyces griseorubens JSD-1
Abstract Streptomyces griseorubens JSD-1 is novel isolate utilizing cellulose as a sole carbon source for growth, and cellulytic genes related to this proceßs were expected to be crucial. To investigate the molecular mechanism of cellulose metabolism, bacterial genome sequencing was carried out. As a result, its draft genome map was obtained which has been deposited… Continue reading Insight into a novel β-1,4-glucosidase from Streptomyces griseorubens JSD-1
Comparative evaluation of cyclic fatigue resistance of four different nickel-titanium rotary files with different cross-sectional designs and alloy properties
Abstract Objective The purpose of the present study was to evaluate the cyclic fatigue resistance of F6 SkyTaper (Komet Brasseler, Lemgo, Germany), K3XF (SybronEndo, Orange, CA, USA), new generation OneShape (Micro Mega, Besancon, France) and TRUShape 3D conforming files (Dentsply Tulsa Dental Specialties, Tulsa, OK, USA). Material and methods Ten instruments from each group were… Continue reading Comparative evaluation of cyclic fatigue resistance of four different nickel-titanium rotary files with different cross-sectional designs and alloy properties
Comparative evaluation of cyclic fatigue resistance of four different nickel-titanium rotary files with different cross-sectional designs and alloy properties
Abstract Objective The purpose of the present study was to evaluate the cyclic fatigue resistance of F6 SkyTaper (Komet Brasseler, Lemgo, Germany), K3XF (SybronEndo, Orange, CA, USA), new generation OneShape (Micro Mega, Besancon, France) and TRUShape 3D conforming files (Dentsply Tulsa Dental Specialties, Tulsa, OK, USA). Material and methods Ten instruments from each group were… Continue reading Comparative evaluation of cyclic fatigue resistance of four different nickel-titanium rotary files with different cross-sectional designs and alloy properties
Bilan d’activité du centre de traitement Ebola de Forécariah (Guinée) du 23 avril au 5 juin 2015 : analyse et réflexions
Résumé Le bilan de l’activité du centre de traitement Ebola (CTE) de Forécariah (Guinée maritime) du 23 avril au 5 juin 2015 est ici présenté. La charge virale du virus Ebola a été évaluée par la mesure du cycle threshold (Ct). Cent trente personnes ont fait l’objet d’un triage, 24 (18,5 %) ne répondant pas… Continue reading Bilan d’activité du centre de traitement Ebola de Forécariah (Guinée) du 23 avril au 5 juin 2015 : analyse et réflexions
Aspects épidémiologiques de la maladie à virus Ebola en Guinée (décembre 2013–avril 2016)
Résumé Le virus Ebola de l’espèce Zaïre variant Makona, entre son émergence en décembre 2013 et avril 2016, a provoqué en Guinée une épidémie d’une importance et d’une gravité sans précédent, avec 3 814 cas notifiés, dont 3 358 ont été confirmés (88,0 %) et 2 544 (66,7 %) sont décédés. L’épidémie a évolué en… Continue reading Aspects épidémiologiques de la maladie à virus Ebola en Guinée (décembre 2013–avril 2016)
Effects of core-to-dentin thickness ratio on the biaxial flexural strength, reliability, and fracture mode of bilayered materials of zirconia core (Y-TZP) and veneer indirect composite resins
Publication date: Available online 25 July 2016 Source:The Journal of Prosthetic Dentistry Author(s): Naichuan Su, Yunmao Liao, Hai Zhang, Li Yue, Xiaowen Lu, Jiefei Shen, Hang Wang Statement of problemIndirect composite resins (ICR) are promising alternatives as veneering materials for zirconia frameworks. The effects of core-to-dentin thickness ratio (C/Dtr) on the mechanical property of bilayered… Continue reading Effects of core-to-dentin thickness ratio on the biaxial flexural strength, reliability, and fracture mode of bilayered materials of zirconia core (Y-TZP) and veneer in... περισσότερα »
Impact of resection of the head of the middle turbinate in endoscopic sinus surgery
otolaryngologistsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.Alexandros,,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,tel : 00302841026182,00306932607174Πριν από 22 δευτερόλεπτα
Impact of resection of the head of the middle turbinate in endoscopic sinus surgery: Hamza El-Shafaai A Ahmed, Mohamed M Osman Pan Arab Journal of Rhinology 2016 6(1):11-15 Aim The aim of the present study was to evaluate the effects of middle turbinate head resection (MTR) on the outcome of endoscopic sinus surgery. Patients and […]
Effect of middle turbinate intervention on outcomes of middle meatal endoscopic surgery
otolaryngologistsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.Alexandros,,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,tel : 00302841026182,00306932607174Πριν από 22 δευτερόλεπτα
Effect of middle turbinate intervention on outcomes of middle meatal endoscopic surgery: Khaled M Bofares Pan Arab Journal of Rhinology 2016 6(1):27-32 Background and objective Middle turbinate position, bulk, and shape play a significant role in the determination of drainage and ventilation at the middle meatus. The middle turbinate constitutes the corner stone for the […]
The incidence of complications after prelacrimal recess approach versus endoscopic sinus surgery of maxillary sinus lesions
otolaryngologistsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.Alexandros,,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,tel : 00302841026182,00306932607174Πριν από 22 δευτερόλεπτα
The incidence of complications after prelacrimal recess approach versus endoscopic sinus surgery of maxillary sinus lesions: Mohammed A AlAyadi, Sherif A Raafat, Khalid A Ateya, Fadi M Gharib, Abdullah M AlMurtada Pan Arab Journal of Rhinology 2016 6(1):16-21 Aim of work The aim of the study was to evaluate the incidence of complications after prelacrimal […]
Pleomorphic adenoma of the nasal septum
otolaryngologistsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.Alexandros,,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,tel : 00302841026182,00306932607174Πριν από 22 δευτερόλεπτα
a case report and review of the literature: Ali Al Momen, Abdulrahman Al Khatib Pan Arab Journal of Rhinology 2016 6(1):36-38 Intranasal pleomorphic adenomas are quite rare and are frequently misdiagnosed . We report a nasal septal pleomorphic adenoma in a 60-year-old man. Rigid endoscopy of the nose revealed a large polypoid mass filling the […]
Otolaryngologic Clinics of North America : Endoscopic Facial Nerve Surgery,Endoscopic Management of Middle Ear and Temporal Bone Lesions
otolaryngologistsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.Alexandros,,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,tel : 00302841026182,00306932607174Πριν από 22 δευτερόλεπτα
Endoscopic Management of Middle Ear and Temporal Bone Lesions by Brandon Isaacson, Joao Flavio Nogueira via Otolaryngologic Clinics of North America Tantamount to the management of temporal bone neoplasms is the ability to visualize the pathology and its relationship with the numerous critical structures housed therein. Transcanal endoscopic ear surgery provides the surgeon with an unparalleled view of […]
Stabilization of the Craniovertebral Junction with Clivus Plate Constructs
otolaryngologistsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.Alexandros,,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,tel : 00302841026182,00306932607174Πριν από 22 δευτερόλεπτα
: Biomechanical Comparison with Conventional Technique via World Neurosurgery Publication date: October 2016Source:World Neurosurgery, Volume 94Author(s): Wei Ji, Jie Tong, Zhiping Huang, Minghui Zheng, Xiuhua Wu, Jianting Chen, Qingan ZhuBackgroundVentral defect caused by resection of the lesions involving the upper cervical spine commonly has been reconstructed with a fabricated mesh cage. Recently, a clival screw and […]
Flexible Microblade Shaver System
otolaryngologistsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.Alexandros,,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,tel : 00302841026182,00306932607174Πριν από 22 δευτερόλεπτα
Lumbar Neuroforaminal Decompression with a Flexible Microblade Shaver System: Results of a Cadaveric Study via World Neurosurgery Publication date: October 2016Source:World Neurosurgery, Volume 94Author(s): Lennart Viezens, Marc Dreimann, Roland Gessler, Martin Stangenberg, Sven Oliver EickerBackgroundThe lumbar neural foraminal stenosis still is a challenging condition in minimally invasive spine surgery. Because of the anatomic situation a complete […]
Radiosurgery for Brainstem Arteriovenous Malformations
otolaryngologistsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.Alexandros,,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,tel : 00302841026182,00306932607174Πριν από 22 δευτερόλεπτα
Management Outcome of Brainstem Arteriovenous Malformations: The Role of Radiosurgery via World Neurosurgery Publication date: October 2016Source:World Neurosurgery, Volume 94Author(s): Wuyang Yang, Jose L. Porras, Tomas Garzon-Muvdi, Risheng Xu, Justin M. Caplan, Alice L. Hung, Maria Braileanu, Xiaoming Rong, Geoffrey P. Colby, Alexander L. Coon, Rafael J. Tamargo, Judy HuangIntroductionManagement decisions for brainstem arteriovenous malformations (AVMs) […]
Microvascular Decompression for Trigeminal Neuralgia
otolaryngologistsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.Alexandros,,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,tel : 00302841026182,00306932607174Πριν από 22 δευτερόλεπτα
: Technical Refinement for Complication Avoidance via World Neurosurgery Publication date: October 2016Source:World Neurosurgery, Volume 94Author(s): Francesco Tomasello, Felice Esposito, Rosaria V. Abbritti, Filippo F. Angileri, Alfredo Conti, Salvatore M. Cardali, Domenico La TorreBackgroundMicrovascular decompression (MVD) represents the most effective and safe surgical option for the treatment of trigeminal neuralgia since it was first popularized by […]
Gamma Knife Surgery for Cavernous Sinus Hemanginoma
otolaryngologistsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.Alexandros,,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,tel : 00302841026182,00306932607174Πριν από 22 δευτερόλεπτα
: A Report of 32 Cases via World Neurosurgery Publication date: October 2016Source:World Neurosurgery, Volume 94Author(s): Yi Wang, Peng Li, Xin J. Zhang, Yang Y. Xu, Wei WangBackgroundCavernous sinus hemangioma (CSH) is a rare type of benign vascular tumor. Microsurgery for CSH treatment usually results in profuse bleeding and cranial nerve injury. Radiosurgery is an alternative […]
Atypical respiratory auscultation
otolaryngologistsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.Alexandros,,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,tel : 00302841026182,00306932607174Πριν από 15 δευτερόλεπτα
Atypical respiratory auscultation: Description An 89-year-old man, with a history of thyroid papillary carcinoma with lymph node and skin metastasis, was admitted to the emergency department with deterioration of his general state and refusal to eat. The patient was without any other associated complaints. The physical examination noted an uncooperative and disoriented patient, pale and […]
Mechanical thrombectomy for pediatric acute ischemic stroke: review of the literature
otolaryngologistsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.Alexandros,,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,tel : 00302841026182,00306932607174Πριν από 15 δευτερόλεπτα
Mechanical thrombectomy for pediatric acute ischemic stroke: review of the literature: Objective Given recent strongly positive randomized controlled adult mechanical thrombectomy trials, we sought to perform a comprehensive review of available literature on IA pediatric stroke intervention, with a focus on modern mechanical devices. Methods PubMed search for pediatric patients undergoing IA treatment of acute […]
ZNRF3 is downregulated in papillary thyroid carcinoma and suppresses the proliferation and invasion of papillary thyroid cancer cells
otolaryngologistsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.Alexandros,,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,tel : 00302841026182,00306932607174Πριν από 15 δευτερόλεπτα
ZNRF3 is downregulated in papillary thyroid carcinoma and suppresses the proliferation and invasion of papillary thyroid cancer cells: Abstract Zinc and ring finger 3 (ZNRF3) is a transmembrane E3 ubiquitin ligase that has emerged as an important regulator of cancer development; however, its cancer-related function remains controversial. Here, we investigated the possible role of ZNRF3 […]
Microfluidic microscopy-assisted label-free approach for cancer screening: automated microfluidic cytology for cancer screening
otolaryngologistsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.Alexandros,,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,tel : 00302841026182,00306932607174Πριν από 15 δευτερόλεπτα
Microfluidic microscopy-assisted label-free approach for cancer screening: automated microfluidic cytology for cancer screening: Abstract Each year, about 7–8 million deaths occur due to cancer around the world. More than half of the cancer-related deaths occur in the less-developed parts of the world. Cancer mortality rate can be reduced with early detection and subsequent treatment of […]
Cdkn2a suppresses metastasis in squamous cell carcinomas induced by the gain-of-function mutant p53R172H
otolaryngologistsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.Alexandros,,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,tel : 00302841026182,00306932607174Πριν από 15 δευτερόλεπτα
Cdkn2a suppresses metastasis in squamous cell carcinomas induced by the gain-of-function mutant p53R172H: ABSTRACT p53 (TP53) is the most frequently mutated gene in squamous cell carcinomas (SCCs) of the skin and head and neck. Certain p53 mutations are oncogenic and promote invasion and metastasis in SCCs. However, it is unclear how the oncogenic function of […]
Woman With Dyspnea and Abdominal Rash
otolaryngologistsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.Alexandros,,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,tel : 00302841026182,00306932607174Πριν από 15 δευτερόλεπτα
Woman With Dyspnea and Abdominal Rash: A 61-year-old Jamaican woman presented with dyspnea and abdominal rash for 2 days, preceded by abdominal pain and vomiting for 2 weeks. She was hypoxic and hypotensive, requiring ventilator and vasopressor support. Computed tomography (CT) of chest, abdomen, and pelvis revealed diffuse ground-glass opacities with patchy infiltrates in the […]
Pituitary Dysfunction: A Case Series of Immune Checkpoint Inhibitor–Related Hypophysitis in an Emergency Department
otolaryngologistsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.Alexandros,,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,tel : 00302841026182,00306932607174Πριν από 15 δευτερόλεπτα
Pituitary Dysfunction: A Case Series of Immune Checkpoint Inhibitor–Related Hypophysitis in an Emergency Department: The development of an anticytotoxic T-lymphocyte antigen-4 antibody1 marked the beginning of a new class of drugs, immune checkpoint inhibitors, which have been found to improve survival in certain types of cancer. Ipilimumab (Yervoy) is the first immune checkpoint inhibitor to […]
Not All Coughs Are Asthma or Allergies: Churg–Strauss Syndrome
otolaryngologistsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.Alexandros,,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,tel : 00302841026182,00306932607174Πριν από 15 δευτερόλεπτα
Not All Coughs Are Asthma or Allergies: Churg–Strauss Syndrome: Cardiomyopathy in patients with Churg–Strauss syndrome (CSS) carries a poor prognosis, with a high 5-year mortality rate, and requires treatment with immunosuppressive therapy. There is no single pathognomonic test or clinical finding for diagnosing CSS; instead, it is based upon meeting four of six criteria. Ani […]
What’s New for Tranexamic Acid?
otolaryngologistsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.Alexandros,,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,tel : 00302841026182,00306932607174Πριν από 15 δευτερόλεπτα
What’s New for Tranexamic Acid?: Tranexamic acid (TXA) is an antifibrinolytic agent that competitively inhibits activation of plasminogen, thereby reducing the conversion of plasminogen to plasmin. This conversion is catalyzed by fibrinolysin, which is an enzyme that degrades fibrin clots, fibrinogen, and other plasma proteins, including the procoagulant factors V and VIII. TXA also directly […]
Epidural Steroid Injection Complicated by Intrathecal Entry, Pneumocephalus, and Chemical Meningitis
otolaryngologistsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.Alexandros,,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,tel : 00302841026182,00306932607174Πριν από 30 δευτερόλεπτα
Epidural Steroid Injection Complicated by Intrathecal Entry, Pneumocephalus, and Chemical Meningitis: Epidural steroid injections are frequently used to treat back and extremity pain. The procedure is generally safe, with a low rate of adverse events, including intrathecal entry, pneumocephalus, and chemical meningitis. http://ift.tt/2a8wOlw
Prehospital Endotracheal Intubation in Warm Climates: Caution is Required
otolaryngologistsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.Alexandros,,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,tel : 00302841026182,00306932607174Πριν από 30 δευτερόλεπτα
Prehospital Endotracheal Intubation in Warm Climates: Caution is Required: Out-of-hospital endotracheal intubation is a frequent procedure for trauma care. Nevertheless, in warm climates, sunlight and heat can interfere with the flow of the usual procedure. They can affect the equipment and hinder the operator. There are few data on this issue. The presentation of this case […]
Prenatal exposure to paracetamol may increase autism spectrum and hyperactivity symptoms in children
otolaryngologistsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.Alexandros,,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,tel : 00302841026182,00306932607174Πριν από 30 δευτερόλεπτα
Prenatal exposure to paracetamol may increase autism spectrum and hyperactivity symptoms in children: A new study from the International Journal of Epidemiology has found that paracetamol (acetaminophen), which is used during pregnancy, has a strong association with autism spectrum symptoms in boys and for both genders in relation to attention-related and hyperactivity symptoms. Read the press release […]
Selecting Appropriate Tests to Assess the Benefits of Bilateral Amplification With Hearing Aids
otolaryngologistsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.Alexandros,,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,tel : 00302841026182,00306932607174Πριν από 1 ώρα
The aim of this study was to investigate the effect of bilateral hearing aids (HA) in subjects with mild and moderate-to-severe hearing loss. This study was designed as a within-subject feasibility study. Bilateral HA use was assessed using different laboratory tests on speech reception, listening effort, noise tolerance, and localization. All data were evaluated with […]
Biosimilars in psoriasis: Clinical practice and regulatory perspectives in Latin America
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 2 δευτερόλεπτα
Abstract Latin American countries view biosimilar agents as an effective approach to curtail health-care expenditures while maintaining the safety and efficacy profile of their branded innovator comparators. To understand the complexities of the regulatory landscape and key therapeutic issues for use of biosimilars to treat moderate to severe psoriasis in Latin America, the International Psoriasis […]
Dermoscopic changes in malignant melanoma after successful treatment with nivolumab: A case report
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 2 δευτερόλεπτα
from #ORL-AlexandrosSfakianakis via simeraentaxei on Inoreader http://ift.tt/2acN96M via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
Clinical feasibility of interstitial brachytherapy using a “hybrid” applicator combining uterine tandem and interstitial metal needles based on CT for locally advanced cervical cancer
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 2 δευτερόλεπτα
Publication date: Available online 26 July 2016 Source:Brachytherapy Author(s): Zhong-Shan Liu, Jie Guo, Xia Lin, Hong-Yong Wang, Ling Qiu, Xiao-Jun Ren, Yun-Feng Li, Bing-Ya Zhang, Tie-Jun Wang PurposeTo explore the dosimetric advantage of target volume and surrounding normal tissue by using interstitial (IS) brachytherapy (BT) based on three-dimensional CT in locally advanced cervical cancer, as […]
Alcohol Causes 7 Types of Cancer – KCWY 13 Where News Comes First
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 2 δευτερόλεπτα
Alcohol Causes 7 Types of Cancer KCWY 13 Where News Comes First … cirrhosis of the liver and cirrhosis of the liver is a big risk of liver cancer but now we know for sure that it’s a higher risk for head and neck cancer like tongue larynx esophageal even surprisingly for women it’s breast […]
Higher occurrence of nausea and vomiting after total hip arthroplasty using general versus spinal anesthesia: an observational study
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 2 δευτερόλεπτα
Under the assumption that postoperative nausea and vomiting (PONV) may occur after total hip arthroplasty (THA) regardless of the anesthetic technique used, it is not clear whether general (GA) or spinal (SA) … from #ORL-AlexandrosSfakianakis via simeraentaxei on Inoreader http://ift.tt/2avKWc5 via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
Late-Stage Afatinib Trials Halted in Head and Neck Cancer – OncLive
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 2 δευτερόλεπτα
OncLive Late-Stage Afatinib Trials Halted in Head and Neck Cancer OncLive Head and Neck Cancer Two phase III trials examining afatinib (Gilotrif) in head and neck cancer have been stopped after an independent panel determined the pan-HER inhibitor was unlikely to demonstrate an efficacy benefit over placebo, according to the … Boehringer stops Gilotrif head […]
Role of BTK in the p53 pathway.
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 2 δευτερόλεπτα
p53 is a tumor suppressor that prevents the emergence of transformed cells by inducing apoptosis or senescence, among other responses. Its functions are regulated tightly by posttranslational modifications. Here we show that Bruton’s tyrosine kinase (BTK) is a novel modulator of p53. We found that BTK is induced in response to DNA damage and p53 […]
Hyaluronan based hydrogels provide an improved model to study megakaryocyte–matrix interactions
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 2 δευτερόλεπτα
Publication date: 1 August 2016 Source:Experimental Cell Research, Volume 346, Issue 1 Author(s): Manuela Currao, Alessandro Malara, Christian A. Di Buduo, Vittorio Abbonante, Lorenzo Tozzi, Alessandra Balduini Hyaluronan (HA) is a glycosamminoglican involved in cell biology as well as a relevant polymer for tissue engineering and regenerative medicine. Megakaryocytes (Mks) are immersed in a mesh […]
IFC/ Editorial Board
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 2 δευτερόλεπτα
Publication date: 1 August 2016 Source:Experimental Cell Research, Volume 346, Issue 1 from #ORL-AlexandrosSfakianakis via simeraentaxei on Inoreader http://ift.tt/29YzFQP via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
Patterns of weight change after the diagnosis of type 2 diabetes in Scotland and their relationship with glycaemic control, mortality and cardiovascular outcomes: a retrospective cohort study
alsfakianakisστοOtolaryngology lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece Crete,Anapafseos 5 Agios Nikolaos 72100,tel : 00302841026182,00306932607174Πριν από 2 δευτερόλεπτα
Objectives To determine weight change patterns in Scottish patients 2 years after diagnosis of type 2 diabetes and to examine these in association with medium-term glycaemic, mortality and cardiovascular outcomes. Setting Using a retrospective cohort design, ethical approval was obtained to link the Scottish diabetes care database to hospital admission and mortality records. Participants 29 […]
Tumor Debulking in the Management of Laryngeal Cancer Airway Obstruction
Alexandros G. SfakianakisστοOtoRhinoLaryngology Now by Alexandros G. SfakianakisΠριν από 5 δευτερόλεπτα
Patients presenting with advanced aerodigestive malignancy and respiratory compromise often undergo tracheotomy as initial airway management. Tumor debulking is a potential alternative. We present a case series with chart review to communicate our institutional experience with this technique. T3/4 glottic and supraglottic cancers treated between 2004 and 2014 underwent review, and 14 patients were identified for this study. Of these, 5 (35.7%) required subsequent tracheotomy, and 9 (64.3%) did not. Patients requiring subsequent tracheotomy had a delay in initiating definitive trea... περισσότερα »
Gabapentin for Perioperative Analgesia in Otorhinolaryngology-Head and Neck Surgery: Systematic Review
Alexandros G. SfakianakisστοOtoRhinoLaryngology Now by Alexandros G. SfakianakisΠριν από 5 δευτερόλεπτα
Objective Recent research has investigated the role of gabapentin in perioperative pain relief in otorhinolaryngology–head and neck surgery. This review aims to identify whether sufficient evidence exists for the routine use of gabapentin in the perioperative setting. Data Sources MEDLINE, Cochrane CENTRAL, EMBASE, and Google Scholar. Review Methods A comprehensive systematic search was performed with keywords for articles up to November 2015. The systematic review included all randomized, placebo-, and active-controlled trials investigating the role of perioperative gabapenti... περισσότερα »
Selecting Appropriate Tests to Assess the Benefits of Bilateral Amplification With Hearing Aids
Alexandros G. SfakianakisστοOtoRhinoLaryngology Now by Alexandros G. SfakianakisΠριν από 5 δευτερόλεπτα
The aim of this study was to investigate the effect of bilateral hearing aids (HA) in subjects with mild and moderate-to-severe hearing loss. This study was designed as a within-subject feasibility study. Bilateral HA use was assessed using different laboratory tests on speech reception, listening effort, noise tolerance, and localization. All data were evaluated with bilateral and unilateral HA fittings. Forty experienced bilateral HA users were included with hearing impairment ranging from mild to moderate-to-severe. Subjects were stratified into two groups based on the degree o... περισσότερα »
Short-stay hospital admission after free tissue transfer for head and neck reconstruction
Alexandros G. SfakianakisστοOtoRhinoLaryngology Now by Alexandros G. SfakianakisΠριν από 5 δευτερόλεπτα
[image: cover.gif?v=1&s=89c747938c409c8905c59b71] Objectives/Hypothesis To show that, for patients with few medical comorbidities and at low risk for airway compromise or fistula formation, early discharge after free tissue transfer for head and neck reconstruction is a safe and viable option. Study Design Retrospective chart review. Methods A cohort of patients who underwent free tissue transfer for head and neck reconstruction between February 2010 and December 2014 and who were discharged from the hospital by postoperative day 3 were reviewed. Results Fifty patients underg... περισσότερα »
Variations in pollen counts between Indianapolis, IN, and Dayton, OH, in spring 2013 and 2014
Alexandros G. SfakianakisστοOtoRhinoLaryngology Now by Alexandros G. SfakianakisΠριν από 5 δευτερόλεπτα
Publication date: Available online 25 July 2016 *Source:*Annals of Allergy, Asthma & Immunology Author(s): Girish Vitalpur, Shaylar Padgett, Kirsten M. Kloepfer, James Slaven, Frederick E. Leickly http://ift.tt/2ady3kI
Successful cyclophosphamide desensitization in a pediatric patient with systemic lupus erythematosus and anaphylaxis after initial exposure
Alexandros G. SfakianakisστοOtoRhinoLaryngology Now by Alexandros G. SfakianakisΠριν από 5 δευτερόλεπτα
Publication date: Available online 26 July 2016 *Source:*Annals of Allergy, Asthma & Immunology Author(s): Yoomie J. Lee, Jennifer Toh, Elina Jerschow, Jenny Shliozberg http://ift.tt/2acBWDb
Preoperative coronary calcium score is predictive of early postoperative cardiovascular complications in liver transplant recipients
Alexandros G. SfakianakisστοOtoRhinoLaryngology Now by Alexandros G. SfakianakisΠριν από 5 δευτερόλεπτα
http://ift.tt/2avt29f
Comparative Study of Apo-Cetirizine Single Therapy and Intermittent Sequential Therapy with Cetirizine, Loratadine and Chlorpheniramine in Allergic Rhinitis
Alexandros G. SfakianakisστοOtoRhinoLaryngology Now by Alexandros G. SfakianakisΠριν από 5 δευτερόλεπτα
Abstract There are limited numbers of articles, studying combined use of antihistamines. In this study, we compare single therapy of Apo-Cetirizine with a new regimen of intermittent sequential therapy with cetirizine, loratadine and chlorpheniramine in treatment of seasonal allergic rhinitis. This randomized clinical trial was performed between April and September at the peak prevalence of seasonal allergic rhinitis. Fifty-four eligible patients diagnosed clinically to have seasonal allergic rhinitis were randomized in two groups: 24 cases in single therapy arm, received Apo-Ceti... περισσότερα »
Functional Endoscopic Sinus Surgery Versus Balloon Sinuplasty with Ethmoidectomy: A 2-year Analysis in Pediatric Chronic Rhinosinusitis
Alexandros G. SfakianakisστοOtoRhinoLaryngology Now by Alexandros G. SfakianakisΠριν από 5 δευτερόλεπτα
Abstract To evaluate the 2-year post-operative outcomes of pediatric patients with chronic rhinosinusitis (CRS) treated with balloon catheter sinuplasty (BCS) and ethmoidectomy compared to functional endoscopic sinus surgery (FESS). Two-group, retrospective cohort study of 28 children with CRS was performed. Of these 28 participants, 15 were treated with traditional FESS (53.6 %) and 13 (46.4 %) underwent traditional ethmoidectomy with balloon sinuplasty. Pre-operative and 2-year postoperative total symptom scores and medications were compared. To examine the potential long-term di... περισσότερα »
Noninvasive Facial Rejuvenation. Part 1: Patient-Directed
Alexandros G. SfakianakisστοOtoRhinoLaryngology Now by Alexandros G. SfakianakisΠριν από 5 δευτερόλεπτα
Seminars in Plastic Surgery 2016; 30: 129-133 DOI: 10.1055/s-0036-1584820 A proper knowledge of noninvasive facial rejuvenation is integral to the practice of a cosmetic surgeon. Noninvasive facial rejuvenation can be divided into patient- versus physician-directed modalities. Patient-directed facial rejuvenation combines the use of facial products such as sunscreen, moisturizers, retinoids, α-hydroxy acids, and various antioxidants to both maintain youthful skin and rejuvenate damaged skin. Physicians may recommend and often prescribe certain products, but the patients are in con... περισσότερα »
