Αρχειοθήκη ιστολογίου

Αλέξανδρος Γ. Σφακιανάκης
ΩτοΡινοΛαρυγγολόγος
Αναπαύσεως 5
Άγιος Νικόλαος Κρήτη 72100
2841026182
6032607174

Τετάρτη 8 Ιουνίου 2016

OtoRhinoLaryngology & Medicine,New Articles,June 9th


Basic Perforator Flap Hemodynamic Mathematical Model

Basic Perforator Flap Hemodynamic Mathematical Model: Background: A mathematical model to help explain the hemodynamic characteristics of perforator flaps based on blood flow resistance systems within the flap will serve as a theoretical guide for the future study and clinical applications of these flaps. Methods: There are 3 major blood flow resistance network systems of […]

No-touch, Single-move Technique to Reverse the Needle While Suturing

No-touch, Single-move Technique to Reverse the Needle While Suturing: Article Outline Author Information From the King Fahad Hospital in Hofuf, Al-Ahsa, Saudi Arabia. Received for publication January 13, 2016; accepted March 9, 2016. Disclosure: The author has no financial interest to declare in relation to the content of this article. The Article Processing Charge was paid […]

Retroseptal Transconjunctival Approach for Blowout Fracture of the Orbital Floor

An Ideal Choice in East-Asian Patients: Objective: To ask experts in the field to evaluate a surgeon’s experience with a retroseptal transconjunctival approach for the repair of the orbital floor damaged by blowout fracture that the surgeon encountered in 12 East-Asian patients. Methods: Patients were identified from a database, and a retrospective case note review […]

First study on 236U in the Northeast Pacific Ocean using a new target preparation procedure for AMS measurements

Alexandros G. SfakianakisστοRadiology by Alexandros G. SfakianakisΠριν από 28 δευτερόλεπτα
[image: S0265931X.gif] Publication date: October 2016 *Source:*Journal of Environmental Radioactivity, Volumes 162–163 Author(s): R. Eigl, P. Steier, S.R. Winkler, K. Sakata, A. Sakaguchi We succeeded in obtaining the depth profile of 236U for a sampling station in the Northeast Pacific Ocean using only one litre of seawater sample from each depth. For this purpose, a new procedure was developed that allowed for the preparation of accelerator mass spectrometry targets for trace uranium using only 100 μg of iron carrier material. The 236U concentrations in water samples from the North... περισσότερα »

Photographic Measurements Partially Correlate to Nasal Function and Appearance among Adult Cleft Patients

Photographic Measurements Partially Correlate to Nasal Function and Appearance among Adult Cleft Patients Author Information From the Department of Surgical Sciences and Plastic and Reconstructive Surgery, Uppsala University Hospital, Uppsala, Sweden. Received for publication August 1, 2015; accepted March 23, 2016. Disclosure: The study was funded by Uppsala University and Uppsala University Hospital research funds. […]

KAP1 Regulates Gene Networks Controlling T cell Development and Responsiveness

FASEB journal : official publication of the Federation of American Societies for Experimental Biology from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1tjjO4M via IFTTT

The Use of Tranexamic Acid in Rhytidectomy Patients

The Use of Tranexamic Acid in Rhytidectomy Patients: Author Information Section of Plastic and Reconstructive Surgery Department of Surgery University of Chicago Medicine Chicago, Ill. Section of Plastic and Reconstructive Surgery Department of Surgery University of Chicago Medicine Chicago, Ill. Plastic and Reconstructive Surgery The Geldner Center Chicago, Ill. Correspondence to Peter D. Geldner, MD, […]

Heads-up 3D Microscopy

An Ergonomic and Educational Approach to Microsurgery: Summary: Traditional microsurgery can lead surgeons to use postures that cause musculoskeletal fatigue, leaving them more prone to work-related injuries. A new technology from TrueVision transmits the microscopic image onto a 3-dimensional (3D) monitor, allowing surgeons to operate while sitting/standing in a heads-up position. The purpose of this […]

Free Flap Elevation Times in Head and Neck Reconstruction Using the Harmonic Scalpel Shears

Free Flap Elevation Times in Head and Neck Reconstruction Using the Harmonic Scalpel Shears: Summary: Free tissue transfer has become the mainstay of head and neck cancer (HNC) reconstructive surgery. The objective of the study is to examine the efficacy of the Harmonic Scalpel (HS) Shears on free flap elevation time and complication rates after […]

Perioperative Antibiotic Dosing and Surgical Site Infection Rate in Office-Based Elective Surgery

Compliance of Background: A best practice goal to reduce surgical site infection includes administration of antibiotics in the ideal preoperative window. This article evaluates an office surgical suite antibiotic administration rate and compares it with the timing of a local hospital treating a similar patient population. The hypothesis was that similar or better compliance and […]

Retinol skin anti-aging properties

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 38 δευτερόλεπτα
Molecular basis of retinol anti-aging properties in naturally aged human skin in vivo: Abstract Objective Retinoic acid has been shown to improve the aged-appearing skin. However, less is known about the anti-aging effects of retinol (ROL, vitamin A), a precursor of retinoic acid, in aged human skin *in vivo*. This study aimed to investigate the molecular basis of retinol anti-aging properties in naturally aged human skin *in vivo*. Methods Sun-protected buttock skin (76±6 years old, n=12) was topically treated with 0.4% ROL and its vehicle for seven days. The effects of topical ROL... περισσότερα »

3-O-Laurylglyceryl ascorbate reinforces skin barrier function

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 38 δευτερόλεπτα
through not only the reduction of oxidative stress but also the activation of ceramide synthesis: Abstract AsA (ascorbic acid), GSH (glutathione), HBSS (Hanks balanced salt solution), HPTLC (high performance thin layer chromatography), IL (interleukin), MAP (magnesium ascorbyl phosphate), NHEKs (normal human epidermal keratinocytes), Nrf2 (nuclear factor E2-related factor 2), PBS (phosphate buffered saline), PPAR (peroxisome proliferator activated receptor), RHEEs (reconstructed human epidermis equivalents), ROS (reactive oxygen species), SC (stratum corneum), SPT (serine palmitoy... περισσότερα »

Cosmetic Vibrators

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 38 δευτερόλεπτα
Effect of the Gel Elasticity of Model Skin Matrices on the Distance/Depth-dependent Transmission of Vibration Energy Supplied from a Cosmetic Vibrator: Abstract objective The purpose of this study is to determine how the energies supplied from a cosmetic vibrator are deeply or far transferred into organs and tissues, and how these depths or distances are influenced by tissue elasticity. methods External vibration energy was applied to model skin surfaces through a facial cleansing vibrator, and we measured a distance- and depth-dependent energy that was transferred to model skin mat... περισσότερα »

Facial-nerve regeneration ability of a hybrid artificial nerve conduit containing uncultured adipose-derived stromal vascular fraction

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 38 δευτερόλεπτα
An experimental study: Purpose This study investigated the potential of uncultured-stromal-vascular-fraction (SVF) cells in promoting facial nerve regeneration in a rat model. Materials and Methods A 7-mm nerve defect was created in the buccal branch of facial nerve in five groups of Lewis rats (total *n* = 30, *n* = 6 per group). A silicone tube, infused with syngeneic uncultured-SVF was implanted into the facial nerve defect. Groups 1–3 received 1 × 103, 1 × 105, and 1 × 107 cells, and regenerated nerves were examined at 13 weeks after the surgery. The findings were compared to t... περισσότερα »

Extended V-Y Advancement Flap Reconstruction of a Large Posterior Upper Midline Trunk Defect

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 38 δευτερόλεπτα
Extended V-Y Advancement Flap Reconstruction of a Large Posterior Upper Midline Trunk Defect: [image: Collapse Box]Author Information From the Division of Plastic Surgery, Brigham and Women’s Hospital, Boston, Mass. Received for publication February 9, 2016; accepted March 23, 2016. *Disclosure:* The authors have no financial interest to declare in relation to the content of this article. The Article Processing Charge was paid for by the authors. Indranil Sinha, MD, 75 Francis St., Boston, MA 02115, E-mail: ISinha@partners.org This is an open-access article distributed under t... περισσότερα »

The Facial Growth Pattern and the Amount of Palatal Bone Deficiency Relative to Cleft Size Should Be Considered in Treatment Planning

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 38 δευτερόλεπτα
The Facial Growth Pattern and the Amount of Palatal Bone Deficiency Relative to Cleft Size Should Be Considered in Treatment Planning: [image: image]Background: The aim of this study is to determine the best surgical/orthodontic treatment plan for the complete bilateral and unilateral cleft lip and palate patient to achieve all treatment goals of facial aesthetics, speech, dental function, and psychosocial development. Methods: Review of 40 years of serial complete bilateral cleft lip and palate and complete unilateral cleft lip and palate dental casts and photographs from birth t... περισσότερα »

Tumoral Calcinosis

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 38 δευτερόλεπτα
An Uncommon Cause for a Mass in a Reconstructed Breast [image: Collapse Box]Author Information From the *Department of Plastic and Reconstructive Surgery, Flinders Medical Centre, Bedford Park, South Australia, Australia; †Department of Surgery, ‡Department of Anatomical Pathology, SA Pathology, and §Department of Pathology, Flinders University, Bedford Park, South Australia, Australia. Received for publication January 28, 2016; accepted March 1, 2016. *Disclosure:* The authors have no financial interest to declare in relation to the content of this article. The Article Processi... περισσότερα »

The Vermilionectomy and the Subsequent Lower Lip Reconstruction Were Introduced by Victor von Bruns and not by von Langenbeck or von Esmarch as Reported Previously

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 38 δευτερόλεπτα
The Vermilionectomy and the Subsequent Lower Lip Reconstruction Were Introduced by Victor von Bruns and not by von Langenbeck or von Esmarch as Reported Previously: [image: Collapse Box]Author Information From the *Department of Cranio-Maxillofacial Plastic Surgery, University of Regensburg, Regensburg, Germany; †Division of Pediatric Facial Plastic Surgery and Craniofacial Anomalies, Catholic Children’s Hospital Wilhelmstift, Hamburg, Teaching Hospital of the University of Luebeck, Germany; ‡Craniofacial Institute, Providence Hospital, Southfield, Mich.; §Department of Crani... περισσότερα »

Malar Reconstruction Using Y-V Advancement Flaps after Tissue Expansion in Treacher Collins Syndrome

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 38 δευτερόλεπτα
Malar Reconstruction Using Y-V Advancement Flaps after Tissue Expansion in Treacher Collins Syndrome: [image: Collapse Box]Author Information From the Department of Plastic and Reconstructive Surgery, Osaka Medical College, Takatsuki, Osaka, Japan. Received for publication October 14, 2015; accepted March 21, 2016. *Disclosure:* The authors have no financial interest to declare in relation to the content of this article. The Article Processing Charge was paid for by the authors. Koichi Ueda, MD, Department of Plastic and Reconstructive Surgery, Osaka Medical College, Takatsuki,... περισσότερα »

Extensive Mine-Shrapnel and Gunshot Wound Closure Using Keystone Island Perforator Flaps

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 38 δευτερόλεπτα
Extensive Mine-Shrapnel and Gunshot Wound Closure Using Keystone Island Perforator Flaps: Background: During military operations, one aspect of a plastic surgeon’s work is to restore extensive and deep wound defects in a short period of time and provide a high degree of functional recovery to the damaged area. Because many injuries caused by military operations cannot be closed using a primary suture, the specialist has to select another surgical approach to close the wound defect. Surgeons must select methods that not only cover the extensive wound defect in 1 step but also allow s... περισσότερα »

Vermilion Reconstruction with Genital Mucosa

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 38 δευτερόλεπτα
Vermilion Reconstruction with Genital Mucosa: [image: image]Summary: Functional and aesthetical reconstruction, especially of the upper lip after ablative tumor surgery, can be very challenging. The skin of the lip might be sufficiently reconstructed by transpositional flaps from the nasolabial or facial area. Large defects of the lip mucosa, including the vestibule, are even more challenging due to the fact that flaps from the inner lining of the oral cavity often lead to functional impairments. We present a case of multiple vermilion and skin resections of the upper lip. At the ... περισσότερα »

Functional Reconstruction of Extensive Lower Lip Defects

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 38 δευτερόλεπτα
Modified Bilateral Neurovascular Cheek Flap [image: image] Background: Reconstruction of extensive lower lip defects is challenging, and functional outcomes are difficult to achieve. Methods: A modified bilateral neurovascular cheek (MBNC) flap has been described. The data of patients with cancer of the lower lip treated with wide excision and reconstructed with the MBNC flap in the Plastic Surgery Unit, Srinagarind Hospital, Khon Kaen University, from 1966 to 2012 were reviewed. Results: Of the total of 143 patients included, 90.91% were women, and their age ranged from 32 to 100 ... περισσότερα »

Functional Reconstruction of Extensive Lower Lip Defects

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 38 δευτερόλεπτα
Modified Bilateral Neurovascular Cheek Flap [image: image] Background: Reconstruction of extensive lower lip defects is challenging, and functional outcomes are difficult to achieve. Methods: A modified bilateral neurovascular cheek (MBNC) flap has been described. The data of patients with cancer of the lower lip treated with wide excision and reconstructed with the MBNC flap in the Plastic Surgery Unit, Srinagarind Hospital, Khon Kaen University, from 1966 to 2012 were reviewed. Results: Of the total of 143 patients included, 90.91% were women, and their age ranged from 32 to 100 ... περισσότερα »

Basic Perforator Flap Hemodynamic Mathematical Model

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 38 δευτερόλεπτα
Basic Perforator Flap Hemodynamic Mathematical Model: [image: image]Background: A mathematical model to help explain the hemodynamic characteristics of perforator flaps based on blood flow resistance systems within the flap will serve as a theoretical guide for the future study and clinical applications of these flaps. Methods: There are 3 major blood flow resistance network systems of a perforator flap. These were defined as the blood flow resistance of an anastomosis between artery and artery of adjacent perforasomes, between artery and vein within a perforasome, and then between ... περισσότερα »

No-touch, Single-move Technique to Reverse the Needle While Suturing

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 38 δευτερόλεπτα
No-touch, Single-move Technique to Reverse the Needle While Suturing: Article Outline [image: Collapse Box]Author Information From the King Fahad Hospital in Hofuf, Al-Ahsa, Saudi Arabia. Received for publication January 13, 2016; accepted March 9, 2016. *Disclosure:* The author has no financial interest to declare in relation to the content of this article. The Article Processing Charge was paid for by the author. Supplemental digital content is available for this article. Clickable URL citations appear in the text. Emran Ali Algadiem, MBBS, King Fahad Hospital in Hofuf Resident o... περισσότερα »

Retroseptal Transconjunctival Approach for Blowout Fracture of the Orbital Floor

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 38 δευτερόλεπτα
An Ideal Choice in East-Asian Patients: [image: image] Objective: To ask experts in the field to evaluate a surgeon’s experience with a retroseptal transconjunctival approach for the repair of the orbital floor damaged by blowout fracture that the surgeon encountered in 12 East-Asian patients. Methods: Patients were identified from a database, and a retrospective case note review was conducted. A total of 12 conjunctival procedures were conducted for the repair of blowout fracture with no other complicating fractures. All operative procedures were done by transconjunctival approac... περισσότερα »

Seroma and skin rash

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 38 δευτερόλεπτα
An Uncommon Presentation of Breast Implant Rupture: [image: image] Summary: Late periprosthetic seroma has lately been concerning for breast implant-associated anaplastic large cell lymphoma. The authors present an uncommon presentation of breast implant rupture with a seroma and skin rash forming 2 years after insertion of the implant.

Better Cleft Care

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 38 δευτερόλεπτα
Ten-Year Cleft Surgery in Nepal: Achievements and Lessons Learned for Better Cleft Care Abroad: Background: Cleft lip and palate surgery abroad is devoid of global consensus regarding standards of therapy, follow-up, and outcome. Cleft surgery in Nepal during a 10-year sustained program provided the opportunity to inform on the need for such standards. Methods: Medical records were evaluated from the cleft clinic at Sushma Koirala Memorial Hospital, Sankhu, Kathmandu, Nepal, from 1997 to 2007. Four groups were identified for analysis: total cohort, total surgical cohort (TSC), pr... περισσότερα »

Intraoperative Indocyanine Green Laser Angiography in Pediatric Autologous Ear Reconstruction

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 38 δευτερόλεπτα
Intraoperative Indocyanine Green Laser Angiography in Pediatric Autologous Ear Reconstruction: Summary: Skin flap vascularity is a critical determinant of aesthetic results in autologous ear reconstruction. In this study, we investigate the use of intraoperative laser-assisted indocyanine green angiography (ICGA) as an adjunctive measure of skin flap vascularity in pediatric autologous ear reconstruction. Twenty-one consecutive pediatric patients undergoing first-stage autologous total ear reconstruction were retrospectively evaluated. The first 10 patients were treated traditiona... περισσότερα »

Photographic Measurements Partially Correlate to Nasal Function and Appearance among Adult Cleft Patients

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 38 δευτερόλεπτα
Photographic Measurements Partially Correlate to Nasal Function and Appearance among Adult Cleft Patients [image: Collapse Box]Author Information From the Department of Surgical Sciences and Plastic and Reconstructive Surgery, Uppsala University Hospital, Uppsala, Sweden. Received for publication August 1, 2015; accepted March 23, 2016. *Disclosure:* The study was funded by Uppsala University and Uppsala University Hospital research funds. The authors have no financial interest to declare in relation to the content of this article. The Article Processing Charge was paid for by... περισσότερα »

The Use of Tranexamic Acid in Rhytidectomy Patients

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 38 δευτερόλεπτα
The Use of Tranexamic Acid in Rhytidectomy Patients: [image: Collapse Box]Author Information Section of Plastic and Reconstructive Surgery Department of Surgery University of Chicago Medicine Chicago, Ill. Section of Plastic and Reconstructive Surgery Department of Surgery University of Chicago Medicine Chicago, Ill. Plastic and Reconstructive Surgery The Geldner Center Chicago, Ill. Correspondence to Peter D. Geldner, MD, University of Chicago Pritzker School of Medicine, The Geldner Center, 680 N Lake Shore Dr. Suite 1325, Chicago, IL 60611 drgeldner@mygeldnercenter.com This... περισσότερα »

Heads-up 3D Microscopy

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 38 δευτερόλεπτα
An Ergonomic and Educational Approach to Microsurgery: [image: image]Summary: Traditional microsurgery can lead surgeons to use postures that cause musculoskeletal fatigue, leaving them more prone to work-related injuries. A new technology from TrueVision transmits the microscopic image onto a 3-dimensional (3D) monitor, allowing surgeons to operate while sitting/standing in a heads-up position. The purpose of this study was to evaluate the feasibility of performing heads-up 3D microscopy as a more ergonomic alternative to traditional microsurgery. A feasibility study was conduct... περισσότερα »

Free Flap Elevation Times in Head and Neck Reconstruction Using the Harmonic Scalpel Shears

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 38 δευτερόλεπτα
Free Flap Elevation Times in Head and Neck Reconstruction Using the Harmonic Scalpel Shears: Summary: Free tissue transfer has become the mainstay of head and neck cancer (HNC) reconstructive surgery. The objective of the study is to examine the efficacy of the Harmonic Scalpel (HS) Shears on free flap elevation time and complication rates after HNC reconstruction compared with traditional electrocautery. A retrospective review of 215 HNC patients undergoing surgical ablation and free flap reconstruction from January 2010 to April 2013 at the University of Alberta Hospital was under... περισσότερα »

Perioperative Antibiotic Dosing and Surgical Site Infection Rate in Office-Based Elective Surgery

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 38 δευτερόλεπτα
Compliance of Background: A best practice goal to reduce surgical site infection includes administration of antibiotics in the ideal preoperative window. This article evaluates an office surgical suite antibiotic administration rate and compares it with the timing of a local hospital treating a similar patient population. The hypothesis was that similar or better compliance and surgical site infection rates can be achieved in the office-based suite. Methods: A total of 277 office-based surgeries were analyzed for antibiotic administration time before incision and their correspond... περισσότερα »

Buttock Fat Transfer Using Ultrasound and Photographic Measurements

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 38 δευτερόλεπτα
Prospective Controlled Study of Buttock Fat Transfer Using Ultrasound and Photographic Measurements: [image: Collapse Box]Author Information From the Swanson Center, Leawood, Kans. Received for publication December 10, 2015; accepted March 9, 2016. *Disclosure:* The author has no financial interest to declare in relation to the content of this article. The Article Processing Charge was paid for by the author. Supplemental digital content is available for this article. Clickable URL citations appear in the text. Eric Swanson, MD, Swanson Center, 11413 Ash Street, Leawood, KS 662... περισσότερα »

Sustainability, Vol. 8, Pages 530: Implications of Reverse Innovation for Socio-Economic Sustainability: A Case Study of Philips China

Αλέξανδρος ΣφακιανάκηςστοMedicine by Alexandros G.SfakianakisΠριν από 40 δευτερόλεπτα
The idea of reverse innovation, local innovation happening in emerging markets for the global market, has gained much academic and managerial attention in recent years. The purpose of this study is to understand how reverse innovation has successfully diffused into the product and market development strategies at Philips Inc., a prominent multinational company (MNC) of the modern era. Furthermore, the study presents the success achieved by these innovations at both the domestic and global levels, along with their implications regarding socio-economic sustainability in emerging mar... περισσότερα »

Genomic Classification and Prognosis in Acute Myeloid Leukemia

Αλέξανδρος ΣφακιανάκηςστοMedicine by Alexandros G.SfakianakisΠριν από 40 δευτερόλεπτα
Acute myeloid leukemia (AML) is characterized by clonal expansion of undifferentiated myeloid precursors, resulting in impaired hematopoiesis and bone marrow failure. Although many patients with AML have a response to induction chemotherapy, refractory disease is common, and relapse represents the… from #Medicine via ola Kala on Inoreader http://ift.tt/1XGvQlr via IFTTT

A comparison of cepstral coefficients and spectral moments in the classification of Romanian fricatives

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 57 δευτερόλεπτα
[image: S00954470.gif] Publication date: July 2016 *Source:*Journal of Phonetics, Volume 57 Author(s): Laura Spinu, Jason Lilley In this paper we explore two methods for the classification of fricatives. First, for the coding of the speech, we compared two sets of acoustic measures obtained from a corpus of Romanian fricatives: (a) spectral moments and (b) cepstral coefficients. Second, we compared two methods of determining the regions of the segments from which the measures would be extracted. In the first method, the phonetic segments were divided into three regions of approximat... περισσότερα »

The development of sex/gender-specific /s/ and its relationship to gender identity in children and adolescents

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 57 δευτερόλεπτα
[image: alertIcon.gif] Publication date: July 2016 *Source:*Journal of Phonetics, Volume 57 Author(s): Fangfang Li, Drew Rendall, Paul L. Vasey, Melissa Kinsman, Amanda Ward-Sutherland, Giancarlo Diano A growing body of literature has revealed sex/gender differences in the acoustics of the sibilant fricative /s/. It has been suggested that some of this sex/gender-related variation might be socially motivated and acquired. However, the necessary developmental research to corroborate this proposal is absent from the literature. To address this, we examined sex/gender differences in th... περισσότερα »

Treatment of Pre-Collapse Stages of Osteonecrosis of the Femoral Head: a Systematic Review of Randomized Control Trials

Alexandros G. SfakianakisστοΝοσολογίαΠριν από 59 δευτερόλεπτα
AbstractBackground Treatment for osteonecrosis of the femoral head (ONFH) remains controversial. Current reviews include low-level evidence studies evaluating the treatment of both pre-collapse and collapse stages of the disease. Questions/Purposes The purpose of the current study is to systematically review the literature evaluating core decompression (CD) with bone marrow mesenchymal cells (BMMCs), CD alone, and bisphosphonate treatment in pre-collapse ONFH by focusing just on randomized clinical trials (RCTs) reporting functional and radiologic outcomes. We aim to determine if t... περισσότερα »

ACL Damage and Deficiency is Associated with More Severe Preoperative Deformity, Lower Range of Motion at the Time of TKA

Alexandros G. SfakianakisστοΝοσολογίαΠριν από 59 δευτερόλεπτα
AbstractBackground ACL status varies in the arthritic knee during TKA. Questions/Purposes The purpose of this study was to examine clinical features and intraoperative findings associated with stages of ACL degeneration. Methods Coronal deformity, ROM, intra-articular degenerative patterns, and ligament releases were assessed for 1656 knees during TKA. Common patterns of deformity and severity of degenerative change were assessed as a function of the severity of ACL deficiency. Results Of the 1656 knees assessed, 27% had a normal ACL, 55% exhibited damage, and 18% exhibited complet... περισσότερα »

The development of sex/gender-specific /s/ and its relationship to gender identity in children and adolescents

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 1 ώρα
[image: alertIcon.gif] Publication date: July 2016 *Source:*Journal of Phonetics, Volume 57 Author(s): Fangfang Li, Drew Rendall, Paul L. Vasey, Melissa Kinsman, Amanda Ward-Sutherland, Giancarlo Diano A growing body of literature has revealed sex/gender differences in the acoustics of the sibilant fricative /s/. It has been suggested that some of this sex/gender-related variation might be socially motivated and acquired. However, the necessary developmental research to corroborate this proposal is absent from the literature. To address this, we examined sex/gender differences in th... περισσότερα »

The Distribution and Severity of Tremor in Speech Structures of Persons with Vocal Tremor

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 1 ώρα
Publication date: Available online 8 June 2016 *Source:*Journal of Voice Author(s): Abby L. Hemmerich, Eileen M. Finnegan, Henry T. Hoffman BackgroundVocal tremor may be associated with cyclic oscillations in the pulmonary, laryngeal, velopharyngeal, or oral regions.ObjectivesThis study aimed to correlate the overall severity of vocal tremor with the distribution and severity of tremor in structures involved.MethodsEndoscopic and clinical examinations were completed on 20 adults with vocal tremor and two age-matched controls during sustained phonation. Two judges rated the severity ... περισσότερα »

Male-specific colon motility dysfunction in the TashT mouse line

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 1 ώρα
Abstract Background In Hirschsprung disease (HSCR), the absence of myenteric neural ganglia in the distal bowel prevents motility and thereby causes functional intestinal obstruction. Although surgical resection of the aganglionic segment allows HSCR children to survive this condition, a number of patients still suffer from impaired motility despite having myenteric ganglia in their postoperative distal bowel. Such phenomenon is also observed in patients suffering from other enteric neuropathies and, in both cases, colonic dysmotility is believed to result from abnormalities of my... περισσότερα »

Emergent airway management in the labor and delivery suite

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 1 ώρα
Publication date: August 2016 *Source:*International Journal of Pediatric Otorhinolaryngology, Volume 87 Author(s): Paul C. Bryson, Kathy Abode, Carlton J. Zdanski IntroductionCongenital airway obstruction is of varied etiology and uncommonly encountered. Prenatal care and imaging have enhanced detection of these abnormalities and allow for multi-disciplinary care planning for airway management at delivery. Despite the availability and advances in prenatal imaging, unanticipated airway obstruction may not be identified until the time of delivery.MethodsCase series.ResultsFour airway ... περισσότερα »

Vocal Tremor

The Distribution and Severity of Tremor in Speech Structures of Persons with via Voice Publication date: Available online 8 June 2016Source:Journal of VoiceAuthor(s): Abby L. Hemmerich, Eileen M. Finnegan, Henry T. HoffmanBackgroundVocal tremor may be associated with cyclic oscillations in the pulmonary, laryngeal, velopharyngeal, or oral regions.ObjectivesThis study aimed to correlate the overall severity of vocal […]

Description and Preliminary Evaluation of a Curriculum for Teaching Conversational Skills to Children With High-Functioning Autism and Other Social Cognition Challenges

Description and Preliminary Evaluation of a Curriculum for Teaching Conversational Skills to Children With High-Functioning Autism and Other Social Cognition Challenges: Purpose The purpose of this clinical focus article is to provide (a) a detailed description of a school-based intervention designed to teach children with high-functioning autism spectrum disorders (HF-ASDs) and other social cognition challenges […]

Allergy and Immunology

11h Neutrophils and viral-induced neurologic disease Publication date: Available online 8 June 2016Source:Clinical Immunology Author(s): Jonathan J. Grist, Brett Marro, Thomas E. LaneInfection of the central nervous system (CNS) by neurotropic viruses represents an increasing worldwide problem in terms of morbidity and mortality for people of… 12h Allergen endotoxins induce T-cell–dependent and non–IgE-mediated nasal […]

Squamous cell carcinomas – Melanoma – Cancer

7m Targeting a Long Noncoding RNA in Breast Cancer The central dogma of molecular biology posits that genes are transcribed into messenger RNA (mRNA), which is then translated into proteins, which, in turn, are ultimately responsible for all cellular functions. Yet recent research has revealed that RNAs that do not encode proteins — known […]

OtoRhinoLaryngology

5h OtoRhinoLaryngology – Alexandros G. Sfakianakis via Alexandros G.Sfakianakis on Inoreader The Distribution and Severity of Tremor in Speech Structures of Persons with Vocal Tremor Vocal tremor may be associated with cyclic oscillations in the pulmonary, laryngeal, velopharyngeal, or oral regions. from Speech via a.lsfakia on Inoreader http://ift.tt/25MOJYd via IFTTT 9h OtoRhinoLaryngology – Alexandros […]

Relationship Between African-American Race and Delirium in the ICU.

Alexandros G. SfakianakisστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 1 ώρα
[image: wk-health-logo.gif] Objectives: Delirium is a highly prevalent syndrome of acute brain dysfunction among critically ill patients that has been linked to multiple risk factors, such as age, preexisting cognitive impairment, and use of sedatives; but to date, the relationship between race and delirium is unclear. We conducted this study to identify whether African-American race is a risk factor for developing ICU delirium. Design: A prospective cohort study. Setting: Medical and surgical ICUs of a university-affiliated, safety net hospital in Indianapolis, IN. Patients: A tot... περισσότερα »

Validity of Different Delirium Assessment Tools for Critically Ill Children: Covariates Matter.

Alexandros G. SfakianakisστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 1 ώρα
[image: wk-health-logo.gif] Objectives: To evaluate test validity of the Pediatric Confusion Assessment Method for the ICU, the Pediatric Anesthesia Emergence Delirium scale, and the newly developed severity scale for the Pediatric Confusion Assessment Method for the ICU; to prospectively assess covariates and their influence on test validity of the scores. Design: Prospective observational cohort study. Setting: PICU of a tertiary care medical center. Patients: Critically ill patients 5 years old or older ventilated or nonventilated with an ICU length of stay of at least 24 hours.... περισσότερα »

EMNerd-The Case of the Differing Perspectives

Alexandros G. SfakianakisστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 1 ώρα
[image: Engraving_sphygmomanometer_Wellcome_L001] The reversal of medical truth is not an uncommon occurrence in today’s world of gullible frequentist methodology. Upon examination of a decade’s worth of publications from the NEJM, Prasad et al found that of the trials examining an established medical practice, 40.2% contradicted the initial data responsible for these medical beliefs. This in part is […] EMCrit by Rory Spiegel. from Emergency Medicine via xlomafota13 on Inoreader http://ift.tt/1Xbkncw via IFTTT

EMNerd-The Case of the Differing Perspectives

Alexandros G. SfakianakisστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 1 ώρα
[image: Engraving_sphygmomanometer_Wellcome_L001] The reversal of medical truth is not an uncommon occurrence in today’s world of gullible frequentist methodology. Upon examination of a decade’s worth of publications from the NEJM, Prasad et al found that of the trials examining an established medical practice, 40.2% contradicted the initial data responsible for these medical beliefs. This in part is […] EMCrit by Rory Spiegel. from Emergency Medicine via xlomafota13 on Inoreader http://ift.tt/1Xbkncw via IFTTT

Characteristics of traditional Chinese medicine users and prescription analysis for pediatric atopic dermatitis: a population-based study

Αλέξανδρος ΣφακιανάκηςστοMedicine by Alexandros G.SfakianakisΠριν από 1 ώρα
Atopic dermatitis among children is an important issue due to relapses and skin manifestations. Traditional Chinese medicine (TCM) is commonly used to treat children with atopic dermatitis. The aim of this stu... from #Medicine via ola Kala on Inoreader http://ift.tt/219rX6d via IFTTT

Anti-platelet activity of panaxatriol saponins is mediated by suppression of intracellular calcium mobilization and ERK2/p38 activation

Αλέξανδρος ΣφακιανάκηςστοMedicine by Alexandros G.SfakianakisΠριν από 1 ώρα
Increased platelet aggregation is implicated in the pathogenesis of ischemic stroke and anti-platelet strategy may contribute to its therapy. Panaxatriol saponin (PTS), the main components extracted from Panax no... from #Medicine via ola Kala on Inoreader http://ift.tt/1VNKcyu via IFTTT

Relationship Between African-American Race and Delirium in the ICU.

Αλέξανδρος ΣφακιανάκηςστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 1 ώρα
[image: wk-health-logo.gif] Objectives: Delirium is a highly prevalent syndrome of acute brain dysfunction among critically ill patients that has been linked to multiple risk factors, such as age, preexisting cognitive impairment, and use of sedatives; but to date, the relationship between race and delirium is unclear. We conducted this study to identify whether African-American race is a risk factor for developing ICU delirium. Design: A prospective cohort study. Setting: Medical and surgical ICUs of a university-affiliated, safety net hospital in Indianapolis, IN. Patients: A tot... περισσότερα »

Validity of Different Delirium Assessment Tools for Critically Ill Children: Covariates Matter.

Αλέξανδρος ΣφακιανάκηςστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 1 ώρα
[image: wk-health-logo.gif] Objectives: To evaluate test validity of the Pediatric Confusion Assessment Method for the ICU, the Pediatric Anesthesia Emergence Delirium scale, and the newly developed severity scale for the Pediatric Confusion Assessment Method for the ICU; to prospectively assess covariates and their influence on test validity of the scores. Design: Prospective observational cohort study. Setting: PICU of a tertiary care medical center. Patients: Critically ill patients 5 years old or older ventilated or nonventilated with an ICU length of stay of at least 24 hours.... περισσότερα »

EMNerd-The Case of the Differing Perspectives

Αλέξανδρος ΣφακιανάκηςστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 1 ώρα
[image: Engraving_sphygmomanometer_Wellcome_L001] The reversal of medical truth is not an uncommon occurrence in today’s world of gullible frequentist methodology. Upon examination of a decade’s worth of publications from the NEJM, Prasad et al found that of the trials examining an established medical practice, 40.2% contradicted the initial data responsible for these medical beliefs. This in part is […] EMCrit by Rory Spiegel. from Emergency Medicine via xlomafota13 on Inoreader http://ift.tt/1Xbkncw

EMNerd-The Case of the Differing Perspectives

Αλέξανδρος ΣφακιανάκηςστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 1 ώρα
[image: Engraving_sphygmomanometer_Wellcome_L001] The reversal of medical truth is not an uncommon occurrence in today’s world of gullible frequentist methodology. Upon examination of a decade’s worth of publications from the NEJM, Prasad et al found that of the trials examining an established medical practice, 40.2% contradicted the initial data responsible for these medical beliefs. This in part is […] EMCrit by Rory Spiegel. from Emergency Medicine via xlomafota13 on Inoreader http://ift.tt/1Xbkncw

Exploiting oncogene-induced replicative stress for the selective killing of Myc-driven tumors

Nature structural & molecular biology from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/28maGw1 via IFTTT

Renal Leiomyoma and Leiomyosarcoma: A Study of 57 Cases.

Primary renal leiomyomas and leiomyosarcomas are rare, and there is a paucity of data regarding the pathologic features and outcomes of patients with these tumors. The objective of this study was to review a large series of renal smooth muscle tumors, in order to more fully elucidate their natural histories. Fifty-seven renal smooth muscle tumors […]

First ultrastructural data on the human tapeworm Taenia asiatica eggs by scanning and transmission electron microscopy (SEM, TEM)

Abstract Humans are definitive hosts of three species of the Taenia genus, namely Taenia solium, Taenia saginata and Taenia asiatica. The relative novelty of the latter explains the lack of knowledge concerning certain relevant aspects related to this parasite, such as its definite geographical distribution and whether its eggs can infect humans or not. So […]

DNA extraction methods and multiple sampling to improve molecular diagnosis of Sarcocystis spp. in cattle hearts

Abstract Molecular detection of Sarcocystis spp. in tissue samples can be useful for experimental and diagnostic purposes. However, the parasite spreads unevenly through tissues, forming tissue cysts, and the cystic wall is an obstacle in DNA extraction protocols. Therefore, adequate sampling and effective disruption of the cysts are essential to improve the accuracy of DNA […]

Water-Gas Shift Reaction Catalyzed by Redox Enzymes on Conducting Graphite Platelets

Journal of the American Chemical Society from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/28mb3H2 via IFTTT

Letter to the editor

Molecular psychiatry from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/22SU9M2 via IFTTT

Relationship Between African-American Race and Delirium in the ICU.

Objectives: Delirium is a highly prevalent syndrome of acute brain dysfunction among critically ill patients that has been linked to multiple risk factors, such as age, preexisting cognitive impairment, and use of sedatives; but to date, the relationship between race and delirium is unclear. We conducted this study to identify whether African-American race is a […]

Validity of Different Delirium Assessment Tools for Critically Ill Children: Covariates Matter.

Objectives: To evaluate test validity of the Pediatric Confusion Assessment Method for the ICU, the Pediatric Anesthesia Emergence Delirium scale, and the newly developed severity scale for the Pediatric Confusion Assessment Method for the ICU; to prospectively assess covariates and their influence on test validity of the scores. Design: Prospective observational cohort study. Setting: PICU […]

Relationship Between African-American Race and Delirium in the ICU.

Objectives: Delirium is a highly prevalent syndrome of acute brain dysfunction among critically ill patients that has been linked to multiple risk factors, such as age, preexisting cognitive impairment, and use of sedatives; but to date, the relationship between race and delirium is unclear. We conducted this study to identify whether African-American race is a […]

Validity of Different Delirium Assessment Tools for Critically Ill Children: Covariates Matter.

Objectives: To evaluate test validity of the Pediatric Confusion Assessment Method for the ICU, the Pediatric Anesthesia Emergence Delirium scale, and the newly developed severity scale for the Pediatric Confusion Assessment Method for the ICU; to prospectively assess covariates and their influence on test validity of the scores. Design: Prospective observational cohort study. Setting: PICU […]

Untargeted saliva metabonomics study of breast cancer based on ultra performance liquid chromatography coupled to mass spectrometry with HILIC and RPLC separations

Αλέξανδρος ΣφακιανάκηςστοMedicine by Alexandros G.SfakianakisΠριν από 1 ώρα
Publication date: 1 September 2016 *Source:*Talanta, Volume 158 Author(s): Liping Zhong, Fei Cheng, Xiaoyong Lu, Yixiang Duan, Xiaodong Wang Breast cancer (BC) is not only the most frequently diagnosed cancer, but also the leading cause of cancer death among women worldwide. This study aimed to screen the potential salivary biomarkers for breast cancer diagnosis, staging, and biomarker discovery. For the first time, a UPLC-MS based method along with multivariate data analysis, was proposed for the global saliva metabonomics analysis and diagnosis of BC, which used both hydrophilic i... περισσότερα »

Relationship Between African-American Race and Delirium in the ICU.

Αλέξανδρος ΣφακιανάκηςστοMedicine by Alexandros G.SfakianakisΠριν από 1 ώρα
[image: wk-health-logo.gif] Objectives: Delirium is a highly prevalent syndrome of acute brain dysfunction among critically ill patients that has been linked to multiple risk factors, such as age, preexisting cognitive impairment, and use of sedatives; but to date, the relationship between race and delirium is unclear. We conducted this study to identify whether African-American race is a risk factor for developing ICU delirium. Design: A prospective cohort study. Setting: Medical and surgical ICUs of a university-affiliated, safety net hospital in Indianapolis, IN. Patients: A tot... περισσότερα »

Validity of Different Delirium Assessment Tools for Critically Ill Children: Covariates Matter.

Αλέξανδρος ΣφακιανάκηςστοMedicine by Alexandros G.SfakianakisΠριν από 1 ώρα
[image: wk-health-logo.gif] Objectives: To evaluate test validity of the Pediatric Confusion Assessment Method for the ICU, the Pediatric Anesthesia Emergence Delirium scale, and the newly developed severity scale for the Pediatric Confusion Assessment Method for the ICU; to prospectively assess covariates and their influence on test validity of the scores. Design: Prospective observational cohort study. Setting: PICU of a tertiary care medical center. Patients: Critically ill patients 5 years old or older ventilated or nonventilated with an ICU length of stay of at least 24 hours.... περισσότερα »

Regulatory T Cells in Infections: Getting It Just Right

from #ORL-AlexandrosSfakianakis via simeraentaxei on Inoreader http://ift.tt/1VNrG9i via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174

A Translational Pharmacology Approach to Predicting Outcomes of Preexposure Prophylaxis Against HIV in Men and Women Using Tenofovir Disoproxil Fumarate With or Without Emtricitabine

Background. A novel translational pharmacology investigation was conducted by combining an in vitro efficacy target with mucosal tissue pharmacokinetic (PK) data and mathematical modeling to determine the number of doses required for effective human immunodeficiency virus (HIV) preexposure prophylaxis (PrEP). Methods. A PK/pharmacodynamic (PD) model was developed by measuring mucosal tissue concentrations of tenofovir, emtricitabine, […]

Climatic Drivers of Diarrheagenic Escherichia coli Incidence: A Systematic Review and Meta-analysis

Background. Positive associations have been noted between temperature and diarrhea incidence, but considerable uncertainty surrounds quantitative estimates of this relationship because of pathogen-specific factors and a scarcity of data on the influence of meteorological factors on the risk of disease. Quantifying these relationships is important for disease prevention and climate change adaptation. Methods. To address […]

Identifying Key Drivers of the Impact of an HIV Cure Intervention in Sub-Saharan Africa

Background. It is unknown what properties would be required to make an intervention in low income countries that can eradicate or control human immunodeficiency virus (HIV) without antiretroviral therapy (ART) cost-effective. Methods. We used a model of HIV and ART to investigate the effect of introducing an ART-free viral suppression intervention in 2022 using Zimbabwe […]

Antibody Levels and Protection After Hepatitis B Vaccine: Results of a 30-Year Follow-up Study and Response to a Booster Dose

Background. The duration of protection in children and adults resulting from hepatitis B vaccination is unknown. In 1981, we immunized a cohort of 1578 Alaska Native adults and children from 15 Alaska communities aged ≥6 months using 3 doses of plasma-derived hepatitis B vaccine. Methods. Persons were tested for antibody to hepatitis B surface antigen […]

A comparison of cepstral coefficients and spectral moments in the classification of Romanian fricatives

Publication date: July 2016 Source:Journal of Phonetics, Volume 57 Author(s): Laura Spinu, Jason Lilley In this paper we explore two methods for the classification of fricatives. First, for the coding of the speech, we compared two sets of acoustic measures obtained from a corpus of Romanian fricatives: (a) spectral moments and (b) cepstral coefficients. Second, […]

The development of sex/gender-specific /s/ and its relationship to gender identity in children and adolescents

Publication date: July 2016 Source:Journal of Phonetics, Volume 57 Author(s): Fangfang Li, Drew Rendall, Paul L. Vasey, Melissa Kinsman, Amanda Ward-Sutherland, Giancarlo Diano A growing body of literature has revealed sex/gender differences in the acoustics of the sibilant fricative /s/. It has been suggested that some of this sex/gender-related variation might be socially motivated and […]

Effects of EPHX1 and CYP3A4*22 genetic polymorphisms on carbamazepine metabolism and drug response among Tunisian epileptic patients

Volume 30, Issue 1, March 2016, pages 16-21<br>10.3109/01677063.2016.1155571<br>Chahra Chbili from #ORL-Sfakianakis via xlomafota13 on Inoreader http://ift.tt/1tj21e7 via IFTTT

A rare form of limb girdle muscular dystrophy (type 2E) seen in an Iranian family detected by autozygosity mapping

Volume 30, Issue 1, March 2016, pages 1-4<br>10.3109/01677063.2016.1141208<br>Marzieh Mojbafan from #ORL-Sfakianakis via xlomafota13 on Inoreader http://ift.tt/22StkYv via IFTTT

Effects of transgenic expression of botulinum toxins in Drosophila

Volume 30, Issue 1, March 2016, pages 22-31<br>10.3109/01677063.2016.1166223<br>Philipp Backhaus from #ORL-Sfakianakis via xlomafota13 on Inoreader http://ift.tt/1tj0QeE via IFTTT

Deficits in social behavioral tests in a mouse model of alternating hemiplegia of childhood

Volume 30, Issue 1, March 2016, pages 42-49<br>10.1080/01677063.2016.1182525<br>Greer S. Kirshenbaum from #ORL-Sfakianakis via xlomafota13 on Inoreader http://ift.tt/22StsXY via IFTTT

Dopamine transporter mutant animals: a translational perspective

Volume 30, Issue 1, March 2016, pages 5-15<br>10.3109/01677063.2016.1144751<br>Evgeniya V. Efimova from #ORL-Sfakianakis via xlomafota13 on Inoreader http://ift.tt/1tj131h via IFTTT

Pharmacological evaluation of orexin receptor antagonists in preclinical animal models of pain

Volume 30, Issue 1, March 2016, pages 32-41<br>10.3109/01677063.2016.1171862<br>Terrence McDonald from #ORL-Sfakianakis via xlomafota13 on Inoreader http://ift.tt/22SsACB via IFTTT

Radiation exposure in patients treated with endovascular aneurysm repair: what is the risk of cancer, and can we justify treating younger patients?

Background Endovascular aneurysm repair (EVAR) is becoming the mainstay treatment of abdominal aortic aneurisms (AAA). The postoperative follow-up regime includes a lifelong series of CT angiograms (CTAs) at different intervals in addition to EVAR, which will confer significant cumulative radiation exposure over time. Purpose To examine the impact of age and follow-up regime over time […]

Association of the miR-146a rs2910164 polymorphism with gastric cancer susceptibility and prognosis

Future Oncology Ahead of Print. from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1YaMHLo via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 &amp; 00306932607174

Immune checkpoint inhibitors as first-line and salvage therapy for advanced non-small-cell lung cancer

Future Oncology Ahead of Print. from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1U8gKRu via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 &amp; 00306932607174

Distance from Dura mater to spinal cord at the thoracic vertebral level: An introductory study on local subdural geometry for thoracic epidural block

Objective To evaluate the anatomical safety margins in relation to thoracic epidural block by analysing magnetic resonance (MR) images. Methods This retrospective study identified consecutive patients who underwent MR imaging of the thoracic vertebral spine. The distance from the dura mater to the spinal cord (DTC) was measured at different thoracic intervertebral levels using three […]

Proprotein convertase subtilisin/kexin type 9 levels and aortic valve calcification: A prospective, cross sectional study

Objective To investigate the possible association between plasma proprotein convertase subtilisin/kexin type 9 (PCSK9) and the incidence and severity of calcific aortic valve disease (CAVD). Methods This prospective, cross sectional study involved patients with and without (controls) aortic valve calcification diagnosed by transthoracic echocardiography and dual source computed tomography (DSCT) scan. Aortic valves calcification scores […]

Effects of combining erlotinib and RNA-interfered downregulation of focal adhesion kinase expression on gastric cancer

Objective To investigate the synergistic effects of combining erlotinib and RNA-interference downregulation of focal adhesion kinase (FAK) expression on the proliferation, apoptosis, invasion and migration of the human gastric adenocarcinoma cell line AGS. Methods Cells were divided into five experimental groups: Group A, nontransfected control; Group B, transfected with empty vector; Group C, transfected with […]