Tumor-derived factors modulating dendritic cell function
Tumor-derived factors modulating dendritic cell function: AbstractDendritic cells (DC) play unique and diverse roles in the tumor occurrence, development, progression and response to therapy. First of all, DC can actively uptake tumor-associated antigens, process them and present antigenic peptides to T cells inducing and maintaining tumor-specific T cell responses. DC interaction with different immune effector cells may also support innate antitumor immunity, as well as humoral responses also known to inhibit tumor development in certain cases. On the other hand, DC are recruited ... περισσότερα »
Stinging insect identification
Stinging insect identification via ScienceDirect Publication: Annals of Allergy, Asthma & Immunology Publication date: Available online 16 March 2016 *Source:*Annals of Allergy, Asthma & Immunology Author(s): Troy W. Baker, Joseph P. Forester, Monica L. Johnson, Jeremy M. Sikora, Adrienne Stolfi, Mark C. Stahl BackgroundIt has been reported that the general population is not skillful at identifying stinging insects with the exception of the honeybee. No information is available to evaluate allergy physicians' accuracy with stinging insect identification.ObjectivesTo measure the accuracy...περισσότερα »
Pollen used to produce allergen extracts
Pollen used to produce allergen extracts via ScienceDirect Publication: Annals of Allergy, Asthma & Immunology Publication date: Available online 16 March 2016 *Source:*Annals of Allergy, Asthma & Immunology Author(s): Rosa Codina, Richard F. Lockey ObjectiveTo review the use of pollen for the production of allergen extracts to diagnose and treat allergic diseases, examine the associated regulations, and highlight candidate areas for improvement.Data SourcesA PubMed search was performed using focused keywords combined with a review of regulatory documents and industry guidelines.Study S... περισσότερα »
Chemoradiation for oropharyngeal squamous cell carcinoma (OPSCC) : Risk factors for prolonged diagnosis to treatment interval (DTI) and survival outcomes
Clinical impact of prolonged diagnosis to treatment interval (DTI) among patients with oropharyngeal squamous cell carcinoma via ScienceDirect Publication: Oral Oncology Publication date: May 2016 *Source:*Oral Oncology, Volume 56 Author(s): Sonam Sharma, Justin Bekelman, Alexander Lin, J. Nicholas Lukens, Benjamin R. Roman, Nandita Mitra, Samuel Swisher-McClure Purpose/objective(s)We examined practice patterns using the National Cancer Data Base (NCDB) to determine risk factors for prolonged diagnosis to treatment interval (DTI) and survival outcomes in patients receiving chemoradiati... περισσότερα »
Clinical implications of mucosal remodeling from chronic rhinosinusitis
Clinical implications of mucosal remodeling from chronic rhinosinusitis: Background Prognostic implications of mucosal remodeling in chronic rhinosinusitis (CRS) remain unclear. Remodeling of respiratory mucosa in asthma is associated with greater medication use and decreased function. This study investigates the implications of mucosal remodeling on long-term clinical outcomes in patients with CRS. Methods A case-control study of adult patients with CRS undergoing endoscopic sinus surgery (ESS) was performed. Mucosal remodeling was defined by squamous metaplasia, subepithelial fibr...περισσότερα »
Evaluation of bacterial transmission to the paranasal sinuses through sinus irrigation
Evaluation of bacterial transmission to the paranasal sinuses through sinus irrigation: Background Saline nasal irrigation is effective in the treatment of sinonasal disorders, including chronic rhinosinusitis (CRS). Despite bacterial contamination in rinse bottles and reports of infections from contaminated irrigation water, tap water is still used by ∼50% of irrigation users, raising a potential public health concern. This study aimed to determine whether bacteria from the water supply used in sinus irrigations colonizes the paranasal sinuses. Methods Samples were taken from the:... περισσότερα »
Human rhinovirus in an infection after peroral Lactobacillus rhamnosus GG consumption
Human rhinovirus in experimental infection after peroral Lactobacillus rhamnosus GG consumption, a pilot study: Background Data has emerged on possible beneficial effects of probiotics in respiratory tract viral infections, but it is unclear if the promising positive effects evidenced are due to a reduced viral load during infections. The aims of this work were to investigate the effect of peroral probiotic *Lactobacillus rhamnosus* GG (American Type Culture Collection [ATCC], Accession No. 53103) consumption on human rhinovirus (HRV) load in nasopharyngeal lavage samples in experi...περισσότερα »
Somnolence effect of cetirizine
Placebo-controlled assessment of somnolence effect of cetirizine: a meta-analysis: Background It has been found that the most common adverse reaction which occurs more frequently on cetirizine than on placebo is somnolence. However, the somnolence rate varied widely among different studies. The objective of this study was to assess the somnolence effect of cetirizine 10 mg daily compared to placebo in patients aged 6 years and older using meta-analysis and explore the sources of heterogeneity among different studies. Methods Databases were searched for randomized controlled trials (...περισσότερα »
Interleukin-9 and interleukin-17C in chronic rhinosinusitis
Interleukin-9 and interleukin-17C in chronic rhinosinusitis: Background Interleukin (IL)-9 and IL-17C have been known to play a role in allergic inflammation, yet, their roles in chronic rhinosinusitis (CRS) are not well defined. IL-9 induces changes in epithelial cell gene expression leading to goblet cell metaplasia, whereas IL-17C is functionally distinct in that its expression can be induced by bacterial challenge and inflammatory stimuli. This study aimed to compare levels of IL-9 and IL-17C in CRS with nasal polyps (CRSwNP) and without nasal polyps (CRSsNP) as well as atopy. M... περισσότερα »
Cost utility analysis of endoscopic sinus surgery for chronic rhinosinusitis
Cost utility analysis of endoscopic sinus surgery for chronic rhinosinusitis: Background The purpose of this work was to evaluate the cost-effectiveness of endoscopic sinus surgery (ESS) compared to medical therapy for patients with chronic rhinosinusitis (CRS). Methods The study design consisted of a microsimulation Markov decision-tree economic model with a 31-year time horizon. A cohort of 489 patients who underwent ESS for CRS were matched 1 to 1 with a cohort of 489 patients from the national Medical Expenditures Panel Survey database who underwent medical management for CRS. ...περισσότερα »
Is advising food allergic patients to avoid food with precautionary allergen labelling out of date?.
Is advising food allergic patients to avoid food with precautionary allergen labelling out of date?.: Purpose of review: Precautionary allergen labelling (PAL) continues to be used by the food manufacturing industry to alert the food allergic consumer that cross-contact may have occurred during the supply chain for ingredients or the manufacturing process. This review will summarize recent evidence regarding use and interpretation of precautionary labels by industry, healthcare professionals, and food allergic consumers. Consumers find precautionary labels difficult to interpret and... περισσότερα »
Venom Immunotherapy Practice
The Impact of National guidelines on Venom Immunotherapy Practice in the UK: Abstract Venom immunotherapy (VIT) is the only effective treatment for prevention of further anaphylactic reactions to bee and wasp stings in allergic individuals. A previous national survey carried out in 2006/7 revealed significant heterogeneity in UK practice [1]. The British Society for Allergy and Clinical Immunology (BSACI) guidelines for the diagnosis and management of hymenoptera venom (HV) allergy were subsequently published in 2011 [2]. This repeat survey was carried out to assess whether publica... περισσότερα »
Mouth Breathing, another Risk Factor for Asthma
Mouth Breathing, another Risk Factor for Asthma: the Nagahama Study: [image: cover.gif?v=1&s=ff195289b99d5ad4af62a487] Abstract Background Allergic rhinitis, a known risk factor for asthma onset, often accompanies mouth breathing. Mouth breathing may bypass the protective function of the nose and is anecdotally considered to increase asthma morbidity. However, there is no epidemiological evidence that mouth breathing is independently associated with asthma morbidity and sensitization to allergens. In this study, we aimed to clarify the association between mouth breathing and ast... περισσότερα »
The lipid-interaction capacity of Sin a 2 and Ara h 1, major mustard and peanut allergens of the cupin superfamily, endorses allergenicity
The lipid-interaction capacity of Sin a 2 and Ara h 1, major mustard and peanut allergens of the cupin superfamily, endorses allergenicity: [image: cover.gif?v=1&s=ff195289b99d5ad4af62a487] Abstract Background Sin a 2 (11S globulin) and Ara h 1 (7S globulin) are major allergens from yellow mustard seeds and peanut, respectively. The ability of these two allergens to interact with lipid components remains unknown. Objective To study the capacity of Sin a 2 and Ara h 1 to interact with lipid components and the potential effects of such interaction in their allergenic capacity. Meth... περισσότερα »
Oral superficial mucocele in cancer patients
Alexandros G. SfakianakisστοHead,Neck,Brain,Cervical Spine and Esophageal Cancers by Alexandros G. SfakianakisΠριν από 2 δευτερόλεπτα
We thank Sarode et al. [1] for their comment and for sharing their experience of superficial mucoceles at the surgical margins of four oral squamous cell carcinoma (chemo-radiation naïve) patients. Beside the pathogenesis of carcinogenic attack that was offered by the authors, an etiology of local pressure should be examined as well [2]; space-occupying lesion may affect minor salivary glands to cause necrotizing sialometaplasia [3,4], and in a same manner a mucocele may be established by local pressure. (Source: Oral Oncology) from squamous cell carcinoma via ok on Inoreader http...περισσότερα »
Clinical impact of prolonged diagnosis to treatment interval (DTI) among patients with oropharyngeal squamous cell carcinoma
Alexandros G. SfakianakisστοHead,Neck,Brain,Cervical Spine and Esophageal Cancers by Alexandros G. SfakianakisΠριν από 2 δευτερόλεπτα
Delays in cancer treatment not only adversely affect patient reported satisfaction but may also lead to disease progression and inferior oncologic outcomes [1–5]. Treatment of head and neck squamous cell cancer (HNSCC) requires complex multidisciplinary care, involving providers from a wide range of clinical specialties, and timely care delivery may be particularly challenging for both providers and patients. (Source: Oral Oncology) from squamous cell carcinoma via ok on Inoreader http://ift.tt/1UBARrZ via IFTTT
Evaluation for High-risk HPV in Squamous Cell Carcinomas and Precursor Lesions Arising in the Conjunctiva and Lacrimal Sac
Alexandros G. SfakianakisστοHead,Neck,Brain,Cervical Spine and Esophageal Cancers by Alexandros G. SfakianakisΠριν από 2 δευτερόλεπτα
High-risk human papilloma virus (HR-HPV) is a well-established causative agent of oropharyngeal squamous cell carcinoma (SCC). In addition, HR-HPV has occasionally been reported to be present in dysplastic and malignant lesions of the conjunctiva and lacrimal sac, although its overall incidence and etiological role in periocular SCC are controversial. Sequential surgical samples of 52 combined cases of invasive SCC (I-SCC) and SCC in situ (SCCIS) from 2 periocular sites (conjunctiva and lacrimal sac) diagnosed over a 14-year period (2000 to 2014) were selected for evaluation, and ...περισσότερα »
These new articles for Endocrinology are available online
These new articles for Endocrinology are available online ------------------------------ Early Release Endocrinology ------------------------------ [image: Endocrinology masthead] ------------------------------ ------------------------------ Endocrinology Home Page Current Issue Past Issues ------------------------------ ------------------------------ ------------------------------ ------------------------------ HoxA13 Stimulates Myometrial Cells to Secrete IL-1beta and Enhance the Expression of Contraction Associated Proteins Haolong Li, et al. | Endocrinology | Mar 16, 2016 A huma... περισσότερα »
Drug Hypersensitivity Reactions
In vitro tests for Drug Hypersensitivity Reactions. An ENDA/EAACI Drug Allergy Interest Group Position Paper: Summary Drug hypersensitivity reactions (DHR) are a matter of great concern, both for outpatient and in hospital care. The evaluation of these patients is complex, since *in vivo* tests have suboptimal sensitivity and can be time-consuming, expensive and potentially risky, especially drug provocation tests. There are several currently available *in vitro* methods that can be classified into two main groups: those that help to characterize the active phase of the reaction an... περισσότερα »
Feasibility of eye-tracking technology to quantify expertise in ultrasound-guided regional anesthesia
Feasibility of eye-tracking technology to quantify expertise in ultrasound-guided regional anesthesia: AbstractUltrasound-guided regional anesthesia (UGRA) requires an advanced procedural skill set that incorporates both sonographic knowledge of relevant anatomy as well as technical proficiency in needle manipulation in order to achieve a successful outcome. Understanding how to differentiate a novice from an expert in UGRA using a quantifiable tool may be useful for comparing educational interventions that could improve the rate at which one develops expertise. Exploring the gaze ... περισσότερα »
Brain natriuretic peptide play a crucial role.The use of [beta]-mimetics and PDE-III inhibitors
The patient with chronic heart failure undergoing surgery.: Purpose of review: Congestive heart failure (CHF) is one of the most common diseases of the elderly patient. The underlying pathophysiology varies considerably and approximately 50% of the patients suffer from CHF with reduced left ventricular ejection fraction. Mortality in the perioperative period is increased in patients with CHF and this holds true for both minor and major surgeries. This review will summarize recent literature in the field of CHF and perioperative outcome in patients undergoing surgery with a special e... περισσότερα »
The patient with Congestive heart failure (CHF) undergoing surgery.
The patient with chronic heart failure undergoing surgery.: Purpose of review: Congestive heart failure (CHF) is one of the most common diseases of the elderly patient. The underlying pathophysiology varies considerably and approximately 50% of the patients suffer from CHF with reduced left ventricular ejection fraction. Mortality in the perioperative period is increased in patients with CHF and this holds true for both minor and major surgeries. This review will summarize recent literature in the field of CHF and perioperative outcome in patients undergoing surgery with a special e... περισσότερα »
The endogenous sleep–wakefulness substances orexin and melanin-concentrating hormone
Ketamine and propofol have opposite effects on postanesthetic sleep architecture in rats: relevance to the endogenous sleep–wakefulness substances orexin and melanin-concentrating hormone: Abstract BackgroundAnesthesia and surgery disturb sleep. Disturbed sleep adversely affects postoperative complications involving the cardiovascular system, diabetes, and infection. General anesthetics share neuronal mechanisms involving endogenous sleep–wakefulness-related substances, such as orexin (OX) and melanin-concentrating hormone (MCH). We evaluated changes in sleep architecture and the ... περισσότερα »
Surgical and Audiologic Comparison Between Sophono and Bone-Anchored Hearing Aids Implantation.
*Surgical and Audiologic Comparison Between Sophono and Bone-Anchored Hearing Aids Implantation.* Clin Exp Otorhinolaryngol. 2016 Mar;9(1):21-6 Authors: Shin JW, Kim SH, Choi JY, Park HJ, Lee SC, Choi JS, Park HQ, Lee HK Abstract OBJECTIVES: Bone-anchored hearing aids (BAHA) occasionally cause soft tissue problems due to abutment. Because Sophono does not have abutment penetrating skin, it is thought that Sophono has no soft tissue problem relating to abutment. On the other hand, transcutaneous device's output is reported to be 10 to 15 dB lower than percutaneous device. Therefore... περισσότερα »
The Effect of Dexpanthenol on Ototoxicity Induced by Cisplatin.
*The Effect of Dexpanthenol on Ototoxicity Induced by Cisplatin.* Clin Exp Otorhinolaryngol. 2016 Mar;9(1):14-20 Authors: Toplu Y, Sapmaz E, Parlakpinar H, Kelles M, Kalcioglu MT, Tanbek K, Kizilay A Abstract OBJECTIVES: This study was aimed to investigate the protective effects of dexpanthenol (Dxp) on against cisplatin-induced ototoxicity. METHODS: To examine this effect, distortion product otoacoustic emissions (DPOAEs) measurements and serum levels of oxidative and antioxidant status (including malondialdehyde, superoxide dismutase, catalase, glutathione, glutathione peroxidas...περισσότερα »
Ketamine and propofol have opposite effects on postanesthetic sleep architecture
Ketamine and propofol have opposite effects on postanesthetic sleep architecture in rats: relevance to the endogenous sleep–wakefulness substances orexin and melanin-concentrating hormone: Abstract BackgroundAnesthesia and surgery disturb sleep. Disturbed sleep adversely affects postoperative complications involving the cardiovascular system, diabetes, and infection. General anesthetics share neuronal mechanisms involving endogenous sleep–wakefulness-related substances, such as orexin (OX) and melanin-concentrating hormone (MCH). We evaluated changes in sleep architecture and the ... περισσότερα »
Surgical and Audiologic Comparison Between Sophono and Bone-Anchored Hearing Aids Implantation.
*Surgical and Audiologic Comparison Between Sophono and Bone-Anchored Hearing Aids Implantation.* Clin Exp Otorhinolaryngol. 2016 Mar;9(1):21-6 Authors: Shin JW, Kim SH, Choi JY, Park HJ, Lee SC, Choi JS, Park HQ, Lee HK Abstract OBJECTIVES: Bone-anchored hearing aids (BAHA) occasionally cause soft tissue problems due to abutment. Because Sophono does not have abutment penetrating skin, it is thought that Sophono has no soft tissue problem relating to abutment. On the other hand, transcutaneous device's output is reported to be 10 to 15 dB lower than percutaneous device. Therefore... περισσότερα »
The Effect of Dexpanthenol on Ototoxicity Induced by Cisplatin.
*The Effect of Dexpanthenol on Ototoxicity Induced by Cisplatin.* Clin Exp Otorhinolaryngol. 2016 Mar;9(1):14-20 Authors: Toplu Y, Sapmaz E, Parlakpinar H, Kelles M, Kalcioglu MT, Tanbek K, Kizilay A Abstract OBJECTIVES: This study was aimed to investigate the protective effects of dexpanthenol (Dxp) on against cisplatin-induced ototoxicity. METHODS: To examine this effect, distortion product otoacoustic emissions (DPOAEs) measurements and serum levels of oxidative and antioxidant status (including malondialdehyde, superoxide dismutase, catalase, glutathione, glutathione peroxidas...περισσότερα »
The choice of double-lumen tube size
How clinical experience leads anesthetists in the choice of double-lumen tube size: Lung separation techniques are used to provide 1-lung ventilation in patients undergoing thoracic, mediastinal, cardiac, vascular, and esophageal procedures [1]. Left-sided double-lumen tubes (DLTs) are the most common devices used for lung isolation because of their greater margin of safety [2]. However, the use of an incorrect DLT size may lead to iatrogenic airway injury or failure to provide proper lung isolation. Anatomical distances are widely different among patients and could not be predi... περισσότερα »
Use of a video laryngoscope to facilitate removal of a long, sharp-pointed blade from the esophagus
Use of a video laryngoscope to facilitate removal of a long, sharp-pointed blade from the esophagus: [image: gr1.sml] Initial management of ingested esophageal foreign bodies involves airway assessment, determination of the requirement for and timing of therapeutic intervention, risk mitigation during removal, and identification of all indicated equipment for retrieval. Long, sharp-pointed objects lodged in the esophagus require emergent attention and should be retrieved endoscopically, if perforation has not occurred. Inducing general anesthesia and rapidly securing the airway... περισσότερα »
Propofol,but not ketamine or midazolam,exerts neuroprotection after ischaemic injury
Propofol, but not ketamine or midazolam, exerts neuroprotection after ischaemic injury by inhibition of Toll-like receptor 4 and nuclear factor kappa-light-chain-enhancer of activated B-cell signalling: A combined in vitro and animal study.: BACKGROUND: Propofol, midazolam and ketamine are widely used in today's anaesthesia practice. Both neuroprotective and neurotoxic effects have been attributed to all three agents. OBJECTIVE: To establish whether propofol, midazolam and ketamine in the same neuronal injury model exert neuroprotective effects on injured neurones in vitro and in vi...περισσότερα »
Interdisciplinary oral health programme (OHP) for early childhood caries (ECC)
Evaluation of a regional German interdisciplinary oral health programme for children from birth to 5 years of age: Abstract ObjectivesThe aim of this prospective birth cohort study was to evaluate the effect of the interdisciplinary oral health programme (OHP) for early childhood caries (ECC) in 5-year-old German children. Material and methodsAll parents of newborns (*n* = 1162; born 2009/2010) were visited after birth by the communal newborn visiting service of Jena, Thuringia, and advised on general and dental health. In the first year of life, children were invited to attend... περισσότερα »
Microbial contamination in intraoral phosphor storage plates
Microbial contamination in intraoral phosphor storage plates: the dilemma: Abstract ObjectivesThe aims of this study were to evaluate microbial contamination in phosphor storage plates in dental radiology services and discuss the possible origin of this contamination. Materials and methodsThe sample comprised 50 phosphor plates: 14 plates from service A, 30 from service B, and 6 in the control group, consisting of plates never used. Damp sterile swabs were rubbed on the phosphor plates, and then transferred to tests tubes containing sterile saline solution. Serial dilutions wer... περισσότερα »
Noise Cancelling Headphones
Noise Cancelling Headphones: Tinnitus is a painful condition that causes people to experience a nearly constant ringing sound in their ears. Infections and certain medical conditions may cause tinnitus to develop, but the most common reason why people get tinnitus is exposure to loud sounds. The more frequently a person is exposed to loud sounds, the more likely they are to develop tinnitus. Noise cancelling headphones for tinnitus use a built-in microphone and electronic circuitry to create a competing noise that cancels out the sound of ringing. There are many benefits to using t... περισσότερα »
Tinnitus Without Hearing Loss
Tinnitus Without Hearing Loss: Tinnitus is characterized by a ringing sound in the ears, but it may also be heard as a buzzing, whirring, chirping or other repetitive sound. The sound may be mild and bothersome, or it may be so loud that it is debilitating. Tinnitus is most commonly associated with hearing loss, such as hearing loss related to damage to the ear drums or other parts of the auditory system. However, tinnitus without hearing loss is possible, and it often requires special treatment for the best results. The Cause of Tinnitus The cause of tinnitus without hearing loss... περισσότερα »
Meniere's disease
University Of Colorado Menieres: Thousands of people are diagnosed with Meniere’s disease each year. Meniere’s often impacts middle-aged adults, but the disease can be present in people of all ages. Since all of the symptoms may not be present in every patient, it can be challenging for doctors to diagnose this disorder. Disease Background Meniere’s disease can be difficult to understand, but scientists have made amazing progress in researching the illness. This disease was initially discovered after a correlation between vertigo and the middle ear was discovered. Research then be... περισσότερα »
Neck-tongue syndrome (NTS) is a headache disorder often initiated by rapid axial rotation of the neck resulting in unilateral neck and/or occipital pain and transient ipsilateral tongue sensory disturbance
Neck-Tongue Syndrome: AbstractNeck-tongue syndrome (NTS) is a headache disorder often initiated by rapid axial rotation of the neck resulting in unilateral neck and/or occipital pain and transient ipsilateral tongue sensory disturbance. In this review, we examine reported cases of NTS since its initial description in 1980 to highlight the significance of this condition in the differential diagnosis of headache in patients presenting with neck pain and altered tongue sensation. The anatomical basis of NTS centers on the C1–C2 facet joint, C2 ventral ramus, and inferior oblique muscl... περισσότερα »
Salivary substitutes
Using mid infrared technology as new method for the determination of the dwell time of salivary substitutes on three dimensional gingiva models: Abstract BackgroundMany people suffer from dry mouth (xerostomia) due to radiotherapy treatment of head and neck cancer, diseases like Sjogren’s syndrome or as adverse effects to prescribed medications. Salivary substitute products like gels or sprays are often used for treatment. Efficacy of those oral care products are regularly assessed by validated or even not validated questionnaires. To determine the adhesion effect over time more o...περισσότερα »
Progressive Transformation of Germinal Centers (PTGC) and neoplastic processes in the head and neck
Papillary Thyroid Cancer in a Child with Progressive Transformation of Germinal Centers: Objectives. To describe the presentation and management of a child with Progressive Transformation of Germinal Centers (PTGC), an uncommon condition characterized by significant persistent lymphadenopathy, who developed papillary thyroid carcinoma and to explore and review potential links between PTGC and neoplastic processes in the head and neck. Methods. Case presentation and literature review are used. Results. A 10-year-old female presented with a right parotid mass and cervical lymphadenopa... περισσότερα »
Significant persistent lymphadenopathy
Papillary Thyroid Cancer in a Child with Progressive Transformation of Germinal Centers: Objectives. To describe the presentation and management of a child with Progressive Transformation of Germinal Centers (PTGC), an uncommon condition characterized by significant persistent lymphadenopathy, who developed papillary thyroid carcinoma and to explore and review potential links between PTGC and neoplastic processes in the head and neck. Methods. Case presentation and literature review are used. Results. A 10-year-old female presented with a right parotid mass and cervical lymphadenopa... περισσότερα »
Papillary Thyroid Cancer in a Child with Progressive Transformation of Germinal Centers
Papillary Thyroid Cancer in a Child with Progressive Transformation of Germinal Centers: Objectives. To describe the presentation and management of a child with Progressive Transformation of Germinal Centers (PTGC), an uncommon condition characterized by significant persistent lymphadenopathy, who developed papillary thyroid carcinoma and to explore and review potential links between PTGC and neoplastic processes in the head and neck. Methods. Case presentation and literature review are used. Results. A 10-year-old female presented with a right parotid mass and cervical lymphadenopa... περισσότερα »
Standard Follow-up Program (SFP) for Head and Neck Cancer Patients Treated With Curative Primary or Postoperative Radiotherapy or Chemoradiation
Standard Follow-up Program (SFP) for Head and Neck Cancer Patients Treated With Curative Primary or Postoperative Radiotherapy or Chemoradiation: *Condition*: Head and Neck Cancer *Intervention*: Radiation: Radiotherapy (primary or postoperative) *Sponsor*: University Medical Center Groningen The primary and general objective of the clinical introduction of the SFP as the current standard of care is to improve the quality of radiotherapy for head and neck cancer patients by reducing radiation-induced side effects without hampering treatment efficacy in terms of locoregional ... περισσότερα »
Standard Follow-Up Program (SFP) for Patients With Esophageal Cancer
Standard Follow-Up Program (SFP) for Patients With Esophageal Cancer: *Condition*: Esophageal Cancer *Intervention*: Radiation: Radiotherapy *Sponsor*: University Medical Center Groningen Motive: In order to improve the treatment technique, a comprehensive follow-up program is needed to obtain all relevant patient, treatment and toxicity data from esophageal cancer patients. Goal: To set-up and maintain a database containing treatment results in terms of tumor control, side effects, complications and patient-reported quality of life. A standard database of patients receiving... περισσότερα »
Rovalpituzumab Tesirine in Delta-Like Protein 3-Expressing Advanced Solid Tumors
Rovalpituzumab Tesirine in Delta-Like Protein 3-Expressing Advanced Solid Tumors: *Conditions*: Malignant Melanoma; Medullary Thyroid Cancer; Glioblastoma; Large Cell Neuroendocrine Carcinoma; Neuroendocrine Prostate Cancer; High Grade Gastroenteropancreatic Neuroendocrine Carcinoma; Other Neuroendocrine Carcinoma; Other Solid Tumors *Intervention*: Drug: Rovalpituzumab tesirine *Sponsor*: Stemcentrx To assess the safety and tolerability of rovalpituzumab tesirine in subjects with specific delta-like protein 3-expressing advanced solid tumors. ConditionInter... περισσότερα »
Tumor genetics (non-synonymous mutation burden > 200 mutations and mutational smoking signature [transversion high]) : Genetic Predictors of Benefit to Pembrolizumab
Genetic Predictors of Benefit to Pembrolizumab: *Conditions*: Carcinoma, Non-Small-Cell Lung; Cancer of the Head and Neck; Urinary Bladder Neoplasms; Esophageal Squamous Cell Carcinoma; Carcinoma, Transitional Cell *Intervention*: Drug: Pembrolizumab *Sponsors*: Columbia University; Merck Sharp & Dohme Corp.; Massachusetts General Hospital The primary objectives are to determine if tumor genetics (non-synonymous mutation burden > 200 mutations and mutational smoking signature [transversion high]) can predict durable clinical benefit (DCB) to pembrolizumab. The ...περισσότερα »
Middle ear capillary haemangioma.Infantile middle ear capillary haemangiomas (MECH)
: Review of literature and appraisal of management options via Auris Nasus Larynx Publication date: Available online 15 March 2016 *Source:*Auris Nasus Larynx Author(s): Ali A. Salamat, Elizabeth Casselden, Jeffrey Theaker, Vincent Batty, Sebastian Thomas Infantile middle ear capillary haemangiomas (MECH) are a rare entity with only five reported cases in the literature. At present there is no consensus regarding the management of such lesions. Extra-cutaneous haemangiomas have been successfully managed with oral propranolol but not yet reported in MECH. We present a further case and ...περισσότερα »
Gabapentin for pain related to radiation-induced mucositis
Randomized trial of standard pain control with or without gabapentin for pain related to radiation-induced mucositis in head and neck cancer via Auris Nasus Larynx Publication date: Available online 15 March 2016 *Source:*Auris Nasus Larynx Author(s): Tomoko Kataoka, Naomi Kiyota, Takanobu Shimada, Yohei Funakoshi, Naoko Chayahara, Masanori Toyoda, Yutaka Fujiwara, Ken-ichi Nibu, Takahide Komori, Ryohei Sasaki, Toru Mukohara, Hironobu Minami ObjectiveRadiation-induced mucositis (RIM) in chemoradiotherapy (CRT) for head and neck cancer (HNC) causes severe pain and worsens CRT compliance,... περισσότερα »
Current concepts: diagnosis and management of food allergy in children.
Current concepts: diagnosis and management of food allergy in children.: Purpose of review: Advances in the prevention and treatment of food allergy have been published in the last few years and are placed in context using a review format. Recent findings: Preventing food allergy has been studied for years with questions of whether avoidance or exposure was a better strategy. Recent research has suggested that peanut allergy can be substantially reduced in high-risk infants through intentional oral exposure. For children with food allergy, the primary treatment remains avoidance, bu... περισσότερα »
Comparación entre adenoamigdalectomía extracapsular con bisturí frío y reducción mediante radiofrecuencia bipolar
Tratamiento quirúrgico del síndrome de apnea obstructiva del sueño infantil: comparación entre adenoamigdalectomía extracapsular con bisturí frío y reducción mediante radiofrecuencia bipolar via Acta Otorrinolaringológica Española Publication date: Available online 15 March 2016 *Source:*Acta Otorrinolaringológica Española Author(s): Eduard Esteller, Juan Carlos Villatoro, Gabriel Pedemonte, Adriana Agüero, Joan Manel Ademà, Montserrat Girabent-Farrés Introducción y objetivosLa cirugía adenoamigdalar para el tratamiento de los niños con apnea obstructiva del sueño es efectiva. La incomo... περισσότερα »
The co-occurrence of an ovarian Sertoli-Leydig cell tumor with a thyroid carcinoma is highly suggestive of a DICER1 syndrome
The co-occurrence of an ovarian Sertoli-Leydig cell tumor with a thyroid carcinoma is highly suggestive of a DICER1 syndrome: AbstractThe DICER1 gene encodes an endoribonuclease involved in the production of mature microRNAs which regulates gene expression through several mechanisms. Carriers of germline *DICER1* mutations are predisposed to a rare cancer syndrome, the DICER1 syndrome. Pleuropulmonary blastoma is the most frequent lesion seen in this syndrome. Thyroid abnormalities are also a common finding, essentially concerning multinodular goiter. However, differentiated thyroi...περισσότερα »
Children with recurrent croup (RC) and persistent laryngomalacia (LM) clinically improve after supraglottoplasty (SGP)
Recurrent croup and persistent laryngomalacia: Clinical resolution after supraglottoplasty via International Journal of Pediatric Otorhinolaryngology Publication date: May 2016 *Source:*International Journal of Pediatric Otorhinolaryngology, Volume 84 Author(s): Patrick D. Munson ObjectivesTo determine if children with recurrent croup (RC) and persistent laryngomalacia (LM) clinically improve after supraglottoplasty (SGP).Material and methodsRetrospective chart review cohort at tertiary care children's hospital consisting of patients diagnosed with LM and RC that underwent SGP from Jul...περισσότερα »
T-cell Lymphoma of Thyroid Gland with Lennert Type of Morphology
T-cell Lymphoma of Thyroid Gland with Lennert Type of Morphology: A Case Report and Review of the Literature: AbstractThe rare entity of primary T-cell lymphoma of thyroid gland may pose great diagnostic and therapeutic challenges to the pathologist and clinician. There are very few case and short series reports of these tumors describing their varied clinicopathologic features in English literature. We report a case of mature T-cell lymphoma of thyroid in a 26 year old male, with unique pseudogranulomatous and lymphohistiocytic Lennert type of morphology, on a background of autoim...περισσότερα »
Parapharyngeal Soft Tissue Chordoma Presenting with Synchronous Cervical Lymph Node Metastasis
A Parapharyngeal Soft Tissue Chordoma Presenting with Synchronous Cervical Lymph Node Metastasis: An Unusual Presentation: AbstractA 63 year old male presented with a three month history of dysphagia, neck swelling and an oropharyngeal swelling on examination. Initial fine needle aspiration cytology and magnetic resonance imaging (done at a peripheral hospital) suggested a salivary gland neoplasm with lymph node metastasis. An infra-temporal approach was employed to excise the tumour mass and a modified radical neck dissection undertaken to remove the cervical metastasis. Histopath... περισσότερα »
Clinical impact of prolonged diagnosis to treatment interval (DTI) among patients with oropharyngeal squamous cell carcinoma
Clinical impact of prolonged diagnosis to treatment interval (DTI) among patients with oropharyngeal squamous cell carcinoma: Delays in cancer treatment not only adversely affect patient reported satisfaction but may also lead to disease progression and inferior oncologic outcomes [1–5]. Treatment of head and neck squamous cell cancer (HNSCC) requires complex multidisciplinary care, involving providers from a wide range of clinical specialties, and timely care delivery may be particularly challenging for both providers and patients.
Oral superficial mucocele in cancer patients
Oral superficial mucocele in cancer patients: We thank Sarode et al. [1] for their comment and for sharing their experience of superficial mucoceles at the surgical margins of four oral squamous cell carcinoma (chemo-radiation naïve) patients. Beside the pathogenesis of carcinogenic attack that was offered by the authors, an etiology of local pressure should be examined as well [2]; space-occupying lesion may affect minor salivary glands to cause necrotizing sialometaplasia [3,4], and in a same manner a mucocele may be established by local pressure.
Thyroid Steal for Graves' Disease
“Thyroid Steal”—A Historical Approach to Thyroid Surgery for Graves' Disease: - Full Text HTML - Full Text PDF (36 KB) - Full Text PDF with Links (39.5 KB) Author information Peter E. Donnelly,1 Denis E. Winch,2 and John Pollard3 1Department of Endocrinology, Royal Prince Alfred Hospital, Newtown, Australia. 2School of Mathematics and Statistics, University of Sydney, Sydney, Australia. 3Anaesthetics, North Manchester AHA, Manchester, United Kingdom. Address correspondence to: *Peter Donnelly, MD FRACP* *Royal Prince Alfred Hospital Medical Centre* *100 Carillon Avenue*...περισσότερα »
Exposure to Thyroid-Disrupting Chemicals: A Transatlantic Call for Action
Exposure to Thyroid-Disrupting Chemicals: A Transatlantic Call for Action: Author information Angela M. Leung,1,2 Tim I.M. Korevaar,3 Robin P. Peeters,3 R. Thomas Zoeller ,4 Josef Köhrle,5Leonidas H. Duntas,6 Gregory A. Brent,1,2 and Barbara A. Demeneix7 1Division of Endocrinology, UCLA David Geffen School of Medicine, Los Angeles, California. 2Division of Endocrinology, VA Greater Los Angeles Healthcare System, Los Angeles, California. 3The Generation R Study Group; Department of Internal Medicine; Rotterdam Thyroid Center; Erasmus Medical Center, Rotterdam, Netherlands. 4Biology Depa... περισσότερα »
Differential Effects of Sepsis and Chronic Inflammation on Diaphragm Muscle Fiber Type, Thyroid Hormone Metabolism, and Mitochondrial Function
Differential Effects of Sepsis and Chronic Inflammation on Diaphragm Muscle Fiber Type, Thyroid Hormone Metabolism, and Mitochondrial Function: Thyroid , Vol. 0, No. 0. Author information Flavia F. Bloise,1,2 Anne H. van der Spek,1 Olga V. Surovtseva,1 Tania Maria Ortiga-Carvalho,2 Eric Fliers,1 and Anita Boelen1 1Department of Endocrinology and Metabolism, Academic Medical Centre, University of Amsterdam, Amsterdam,The Netherlands. 2Institute of Biophysics Carlos Chagas Filho, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil. Address correspondence to: *Flavia Bloise, ...περισσότερα »
Weight Loss and Variation of Levothyroxine Requirements in Hypothyroid Obese Patients After Bariatric Surgery
Weight Loss and Variation of Levothyroxine Requirements in Hypothyroid Obese Patients After Bariatric Surgery: Thyroid , Vol. 0, No. 0. Author information Paola Fierabracci, Silvia Martinelli, Anna Tamberi, Paolo Piaggi, Alessio Basolo, Caterina Pelosini,Ilaria Ricco, Silvia Magno, Giorgia Querci, Giovanni Ceccarini, Giovanna Scartabelli, Guido Salvetti,Paolo Vitti, and Ferruccio Santini Obesity Center, Endocrinology Unit 1, University Hospital of Pisa, Pisa, Italy. Address correspondence to: *Paola Fierabracci, MD* *UO Endocrinologia 1* *Ospedale Cisanello* *Via Paradisa 2* *Pisa... περισσότερα »
Intranasal fentanyl for the prehospital management of acute pain in children.
Introduction: Acute pain is the most common symptom in the emergency setting and its optimal management continues to challenge prehospital emergency care practitioners, particularly in the paediatric population. Difficulty in establishing vascular access and fear of opiate administration to small children are recognized reasons for oligoanalgesia. Intranasal fentanyl (INF) has been shown to be as safe and effective as intravenous morphine in the treatment of severe pain in children in the Emergency Department setting. Aim: This study aimed to describe the clinical efficacy and safet... περισσότερα »
Large arterial occlusive strokes as a medical emergency: need to accurately predict clot location.
Background: Endovascular treatment for acute ischemic stroke with a large intracranial occlusion was recently shown to be effective. Timely knowledge of the presence, site, and extent of arterial occlusions in the ischemic territory has the potential to influence patient selection for endovascular treatment. We aimed to find predictors of large vessel occlusive strokes, on the basis of available demographic, clinical, radiological, and laboratory data in the emergency setting. Methods: Patients enrolled in ASTRAL registry with acute ischemic stroke and computed tomography (CT)-angio... περισσότερα »
Molecular Characterization of Methicillin-Resistant Staphylococcus aureus Bloodstream Isolates in a Turkish University Hospital Between 2002 and 2012
AlexAndros SfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026Πριν από 1 ώρα
Microbial Drug Resistance , Vol. 0, No. 0. from Mary Ann Liebert, Inc. publishers via xlomafota13 on Inoreader http://ift.tt/255AjiX via IFTTT
Small-Colony Variants in Persistent and Recurrent Staphylococcus aureus Bacteremia
AlexAndros SfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026Πριν από 1 ώρα
Microbial Drug Resistance , Vol. 0, No. 0. from Mary Ann Liebert, Inc. publishers via xlomafota13 on Inoreader http://ift.tt/1nQ6W2c via IFTTT
Enterococcus faecium ST17 from Coastal Marine Sediment Carrying Transferable Multidrug Resistance Plasmids
AlexAndros SfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026Πριν από 1 ώρα
Microbial Drug Resistance , Vol. 0, No. 0. from Mary Ann Liebert, Inc. publishers via xlomafota13 on Inoreader http://ift.tt/255Aj2u via IFTTT
Molecular and Phenotypic Characterization of Multidrug-Resistant Clones of Staphylococcus epidermidis in Iranian Hospitals: Clonal Relatedness to Healthcare-Associated Methicillin-Resistant Isolates in Northern Europe
AlexAndros SfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026Πριν από 1 ώρα
Microbial Drug Resistance , Vol. 0, No. 0. from Mary Ann Liebert, Inc. publishers via xlomafota13 on Inoreader http://ift.tt/1nQ6VLM via IFTTT
Whole Genome Sequence Analysis of Pig Respiratory Bacterial Pathogens with Elevated Minimum Inhibitory Concentrations for Macrolides
AlexAndros SfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026Πριν από 1 ώρα
Microbial Drug Resistance , Vol. 0, No. 0. from Mary Ann Liebert, Inc. publishers via xlomafota13 on Inoreader http://ift.tt/1M9JTLp via IFTTT
Resting arterial hypoxemia in subjects with chronic heart failure, pulmonary hypertension and patent foramen ovale
AlexAndros SfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026Πριν από 1 ώρα
The roles of intrapulmonary and intracardiac shunt in contributing to arterial hypoxemia at rest in chronic heart failure (CHF) subjects have not been well investigated. We hypothesized that blood flow through intrapulmonary arteriovenous anastomoses (QIPAVA) and/or patent foramen ovale (QPFO) could potentially contribute to arterial hypoxemia and, with pulmonary hypertension (PH) secondary to CHF, this contribution may be exacerbated. Fifty-six CHF subjects (New York Heart Association Classes I-III), with (+) and without (−) PH defined as peak tricuspid regurgitation velocity (T... περισσότερα »
Photodynamic Therapy in Patients with Advanced Hilar Cholangiocarcinoma: Percutaneous Cholangioscopic Versus Peroral Transpapillary Approach
Photomedicine and Laser Surgery , Vol. 0, No. 0. from NeuroSurgery via xlomafota13 on Inoreader http://ift.tt/22mkZj9 via IFTTT
Effects of CO2 Lasers on Dental Pulp Biology in Rats
Photomedicine and Laser Surgery , Vol. 0, No. 0. from NeuroSurgery via xlomafota13 on Inoreader http://ift.tt/1XwK58f via IFTTT
Bactericidal Efficacy of Photodynamic Therapy Against Periodontal Pathogens in Periodontal Disease: A Systematic Review
Photomedicine and Laser Surgery , Vol. 0, No. 0. from NeuroSurgery via xlomafota13 on Inoreader http://ift.tt/22ml1aN via IFTTT
Complications with allogeneic, cancellous bone blocks in vertical alveolar ridge augmentation: prospective clinical case study and review of the literature
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 1 ώρα
Vertical bone augmentation procedures in dental implantology are an indication for cancellous allogeneic bone blocks (ABB). Though, these materials may lead to adverse reactions as known well from orthopedics but rarely published. Therefore, an evaluation of ABB in vertical bone augmentation in clinical dental implantology was conducted. from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1Mo9laM via […]
Increased dementia risk in women – a matter of proteins?
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 1 ώρα
Gender-specific differences between the levels and structures of proteins present in the white matter and the mitochondria of the brains of men and women suffering from dementia have been revealed… from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1pvjA8R via IFTTT
Oral superficial mucocele in cancer patients
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 1 ώρα
We thank Sarode et al. [1] for their comment and for sharing their experience of superficial mucoceles at the surgical margins of four oral squamous cell carcinoma (chemo-radiation naïve) patients. Beside the pathogenesis of carcinogenic attack that was offered by the authors, an etiology of local pressure should be examined as well [2]; space-occupying lesion […]
7 Simple Things Women Can Do To Reduce Their Cancer Risk – Rescu
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 1 ώρα
7 Simple Things Women Can Do To Reduce Their Cancer Risk Rescu Watch what you drink: There is convincing evidence that drinking alcohol increases the risk of cancers of the bowel, breast, liver, mouth, throat, larynx and oesophagus. The more you drink, the greater the risk; and the type of alcohol you drink doesn … […]
Closed mallet thumb injury: Our experience of 10 cases treated with surgery and a systematic review
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 1 ώρα
This retrospective study reports 10 cases of closed mallet thumb injury treated with surgery and compares the clinical outcomes achieved with those of previously described cases which were treated with either conservative therapy or surgery. from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1nPMPkZ via IFTTT
Pial Synangiosis Ameliorates Movement Disorders in the Absence of Prior Stroke in Moyamoya Disease
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 1 ώρα
Background: Moyamoya disease is a rare cerebrovascular disease characterized by progressive stenosis of the bilateral distal internal carotid arteries and their proximal branches. Both chorea and dystonia have been reported as the initial presentation of moyamoya disease. Objective: The objective was to define the clinical presentation and describe the disease course following pial synangiosis of […]
The free scapular flap with latissimus muscle reduces fistulas in mandibular reconstruction
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 1 ώρα
The free scapular chimeric flap is a less common choice for facial reconstruction. Our aim in this study was to evaluate the versatility and safety of the flap, the procedure for a two-team approach, the safety of the osteotomies, and the possibility of dental implants as well as donor site sequelae and complications. from #Medicine-SfakianakisAlexandros […]
The effect of intercostal artery reimplantation on spinal cord injury in thoracoabdominal aortic aneurysm surgery
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 1 ώρα
Intercostal artery (ICA) reimplantation (ICAR) is thought to decrease spinal cord injury (SCI) in thoracic aortic aneurysm and thoracoabdominal aortic aneurysm (TAAA) surgery. Patients treated from 1989 to 2005 without ICAR were compared with those treated from 2005 to 2013 with ICAR to determine whether ICAR reduced SCI. We hypothesized that ICAR would reduce SCI, […]
A new strategy for total auricular reconstruction using prelamination of extended retroauricular flap with tissue expansion
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 1 ώρα
To accomplish total ear reconstruction with aesthetic appearance is a great challenge for plastic surgeons worldwide due to insufficient skin coverage. A retroauricular fascia flap and skin graft technique are commonly used, but the results are unsatisfied due to color mismatch, severe edema, and donor site morbidity. Here, we will describe a novel strategy for […]
Survey of Neurological Disorders in Children Aged 9-15 Years in Northern India
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 1 ώρα
The prevalence of neurological disorders in resource-poor settings, although likely to be high, is largely unexplored. The prevalence and risk factors for neurological disorders, including epilepsy and intellectual, motor, vision, and hearing deficits, in children aged 9 to 15 years in the community were investigated. A new instrument was developed, validated, and used in a […]
A Feasibility Study Evaluating Extraoral Photobiomodulation Therapy for Prevention of Mucositis in Pediatric Hematopoietic Cell Transplantation
Photomedicine and Laser Surgery , Vol. 0, No. 0. from NeuroSurgery via xlomafota13 on Inoreader http://ift.tt/1RnRodI via IFTTT
Photodynamic Therapy in Patients with Advanced Hilar Cholangiocarcinoma: Percutaneous Cholangioscopic Versus Peroral Transpapillary Approach
Photomedicine and Laser Surgery , Vol. 0, No. 0. from NeuroSurgery via xlomafota13 on Inoreader http://ift.tt/1UhxHLg via IFTTT
Effects of CO2 Lasers on Dental Pulp Biology in Rats
Photomedicine and Laser Surgery , Vol. 0, No. 0. from NeuroSurgery via xlomafota13 on Inoreader http://ift.tt/1RnRmCK via IFTTT
Bactericidal Efficacy of Photodynamic Therapy Against Periodontal Pathogens in Periodontal Disease: A Systematic Review
Photomedicine and Laser Surgery , Vol. 0, No. 0. from NeuroSurgery via xlomafota13 on Inoreader http://ift.tt/1UhxHL5 via IFTTT
University Of Colorado Menieres
Thousands of people are diagnosed with Meniere’s disease each year. Meniere’s often impacts middle-aged adults, but the disease can be present in people of all ages. Since all of the symptoms may not be present in every patient, it can be challenging for doctors to diagnose this disorder. Disease Background Meniere’s disease can be difficult to understand, but scientists have made amazing progress in researching the illness. This disease was initially discovered after a correlation between vertigo and the middle ear was discovered. Research then began to show that problems in the m... περισσότερα »
A Feasibility Study Evaluating Extraoral Photobiomodulation Therapy for Prevention of Mucositis in Pediatric Hematopoietic Cell Transplantation
Photomedicine and Laser Surgery , Vol. 0, No. 0. from NeuroSurgery via xlomafota13 on Inoreader http://ift.tt/1QZ9LK7 via IFTTT
Photodynamic Therapy in Patients with Advanced Hilar Cholangiocarcinoma: Percutaneous Cholangioscopic Versus Peroral Transpapillary Approach
Photomedicine and Laser Surgery , Vol. 0, No. 0. from NeuroSurgery via xlomafota13 on Inoreader http://ift.tt/1RnKGEA via IFTTT
University Of Colorado Menieres
Thousands of people are diagnosed with Meniere's disease each year. Meniere's often impacts middle-aged adults, but the disease can be present in people of all ages. Since all of the symptoms may not be present in every patient, it can be challenging for doctors to diagnose this disorder. Disease Background Meniere's disease can be difficult to understand, but scientists have made amazing progress in researching the illness. This disease was initially discovered after a correlation between vertigo and the middle ear was discovered. Research then began to show that problems in the m... περισσότερα »
Dermoscopic and Reflectance Confocal Microscopy Findings in Extra-genital HPV16-associated Pigmented Squamous Cell Carcinoma in situ.
Alexandros G. SfakianakisστοHead,Neck,Brain,Cervical Spine and Esophageal Cancers by Alexandros G. SfakianakisΠριν από 3 ώρες
Authors: Blumetti TP, Scope A, Macedo MP, Ferreira JB, Gomes EE, Enokihara MY, Pinto CA, Nascimento MM, Rezze GG, Braga JC Abstract is missing (Short communication). PMID: 26976508 [PubMed - as supplied by publisher] (Source: Acta Dermato-Venereologica) from squamous cell carcinoma via ok on Inoreader http://ift.tt/1QZt4Sw via IFTTT
Regulation of Oral Squamous Cell Carcinoma Proliferation Through Crosstalk Between SMAD7 and CYLD
Alexandros G. SfakianakisστοHead,Neck,Brain,Cervical Spine and Esophageal Cancers by Alexandros G. SfakianakisΠριν από 3 ώρες
Conclusion: Suppression of CYLD in OSCC cells may promote SMAD7-mediated cancer invasion. Thus, CYLD appears to be an intriguing therapeutic target to prevent OSCC metastases.Cell Physiol Biochem 2016;38:1209-1217 (Source: Cellular Physiology and Biochemistry) *MedWorm Sponsor Message:* Directory of the best January Sales in the UK. Find the best Christmas presents too. from squamous cell carcinoma via ok on Inoreader http://ift.tt/1Veaau2 via IFTTT
Regulation of Oral Squamous Cell Carcinoma Proliferation Through Crosstalk Between SMAD7 and CYLD
Alexandros G. SfakianakisστοHead,Neck,Brain,Cervical Spine and Esophageal Cancers by Alexandros G. SfakianakisΠριν από 3 ώρες
Conclusion: Suppression of CYLD in OSCC cells may promote SMAD7-mediated cancer invasion. Thus, CYLD appears to be an intriguing therapeutic target to prevent OSCC metastases.Cell Physiol Biochem 2016;38:1209-1217 (Source: Cellular Physiology and Biochemistry) *MedWorm Sponsor Message:* Directory of the best January Sales in the UK. Find the best Christmas presents too. from squamous cell carcinoma via ok on Inoreader http://ift.tt/1QZt3Oo via IFTTT
Regulation of Oral Squamous Cell Carcinoma Proliferation Through Crosstalk Between SMAD7 and CYLD
Alexandros G. SfakianakisστοHead,Neck,Brain,Cervical Spine and Esophageal Cancers by Alexandros G. SfakianakisΠριν από 3 ώρες
Conclusion: Suppression of CYLD in OSCC cells may promote SMAD7-mediated cancer invasion. Thus, CYLD appears to be an intriguing therapeutic target to prevent OSCC metastases.Cell Physiol Biochem 2016;38:1209-1217 (Source: Cellular Physiology and Biochemistry) *MedWorm Sponsor Message:* Directory of the best January Sales in the UK. Find the best Christmas presents too. from squamous cell carcinoma via ok on Inoreader http://ift.tt/1Veaady via IFTTT
Dermoscopic and Reflectance Confocal Microscopy Findings in Extra-genital HPV16-associated Pigmented Squamous Cell Carcinoma in situ.
Alexandros G. SfakianakisστοHead,Neck,Brain,Cervical Spine and Esophageal Cancers by Alexandros G. SfakianakisΠριν από 3 ώρες
Authors: Blumetti TP, Scope A, Macedo MP, Ferreira JB, Gomes EE, Enokihara MY, Pinto CA, Nascimento MM, Rezze GG, Braga JC Abstract is missing (Short communication). PMID: 26976508 [PubMed - as supplied by publisher] (Source: Acta Dermato-Venereologica) from squamous cell carcinoma via ok on Inoreader http://ift.tt/1QZt3xT via IFTTT
Effects of CO2 Lasers on Dental Pulp Biology in Rats
Photomedicine and Laser Surgery , Vol. 0, No. 0. from NeuroSurgery via xlomafota13 on Inoreader http://ift.tt/1MoaEXd via IFTTT
Bactericidal Efficacy of Photodynamic Therapy Against Periodontal Pathogens in Periodontal Disease: A Systematic Review
Photomedicine and Laser Surgery , Vol. 0, No. 0. from NeuroSurgery via xlomafota13 on Inoreader http://ift.tt/22m5GH7 via IFTTT
The utility of positron emission tomography with and without computed tomography in patients with nonmelanoma skin cancer
Combined positron emission tomography (PET) and computed tomography (CT) scans are widely used in the staging and monitoring of most malignancies. The differential for PET-positive cutaneous lesions includes primary skin cancers, infections, cutaneous metastases from distant malignancies, and benign neoplasms. In dermatology, PET/CT scans have been most widely studied in patients with melanoma and Merkel cell carcinoma. The role of PET/CT scans in the management of other cutaneous malignancies is less clear, but it has shown great promise in the management of patients with squamou... περισσότερα »
The utility of positron emission tomography with and without computed tomography in patients with nonmelanoma skin cancer
Combined positron emission tomography (PET) and computed tomography (CT) scans are widely used in the staging and monitoring of most malignancies. The differential for PET-positive cutaneous lesions includes primary skin cancers, infections, cutaneous metastases from distant malignancies, and benign neoplasms. In dermatology, PET/CT scans have been most widely studied in patients with melanoma and Merkel cell carcinoma. The role of PET/CT scans in the management of other cutaneous malignancies is less clear, but it has shown great promise in the management of patients with squamou... περισσότερα »
The utility of positron emission tomography with and without computed tomography in patients with nonmelanoma skin cancer
Combined positron emission tomography (PET) and computed tomography (CT) scans are widely used in the staging and monitoring of most malignancies. The differential for PET-positive cutaneous lesions includes primary skin cancers, infections, cutaneous metastases from distant malignancies, and benign neoplasms. In dermatology, PET/CT scans have been most widely studied in patients with melanoma and Merkel cell carcinoma. The role of PET/CT scans in the management of other cutaneous malignancies is less clear, but it has shown great promise in the management of patients with squamou... περισσότερα »
Regulation of Oral Squamous Cell Carcinoma Proliferation Through Crosstalk Between SMAD7 and CYLD
Alexandros G. SfakianakisστοHead,Neck,Brain,Cervical Spine and Esophageal Cancers by Alexandros G. SfakianakisΠριν από 4 ώρες
Conclusion: Suppression of CYLD in OSCC cells may promote SMAD7-mediated cancer invasion. Thus, CYLD appears to be an intriguing therapeutic target to prevent OSCC metastases.Cell Physiol Biochem 2016;38:1209-1217 (Source: Cellular Physiology and Biochemistry) *MedWorm Sponsor Message:* Directory of the best January Sales in the UK. Find the best Christmas presents too. from squamous cell carcinoma via ok on Inoreader http://ift.tt/1Vea71x via IFTTT
Oral superficial mucocele in cancer patients
Alexandros G. SfakianakisστοHead,Neck,Brain,Cervical Spine and Esophageal Cancers by Alexandros G. SfakianakisΠριν από 4 ώρες
We thank Sarode et al. [1] for their comment and for sharing their experience of superficial mucoceles at the surgical margins of four oral squamous cell carcinoma (chemo-radiation naïve) patients. Beside the pathogenesis of carcinogenic attack that was offered by the authors, an etiology of local pressure should be examined as well [2]; space-occupying lesion may affect minor salivary glands to cause necrotizing sialometaplasia [3,4], and in a same manner a mucocele may be established by local pressure. from squamous cell carcinoma via ok on Inoreader http://ift.tt/1S53Ou4 via IF... περισσότερα »
