Assessment of fully-automated atlas-based segmentation of novel oral mucosal surface organ-at-risk.
*Assessment of fully-automated atlas-based
segmentation of novel oral mucosal surface organ-at-risk.*Radiother Oncol. 2016
Mar 9;Authors: Dean JA, Welsh LC, McQuaid D, Wong KH, Aleksic A, Dunne E, Islam
MR, Patel A, Patel P, Petkar I, Phillips I, Sham J, Newbold KL, Bhide SA,
Harrington KJ, Gulliford SL, Nutting CMAbstractBACKGROUND AND PURPOSE: Current
oral mucositis normal tissue complication probability models, based on the dose
distribution to the oral cavity volume, have suboptimal predictive power.
Improving the delineation of the oral mucosa is likely to improve these
...περισσότερα »
Recurrent G12V pathogenic mutation in adenomatoid odontogenic tumours
The adenomatoid odontogenic tumour (AOT) is a
non-aggressive encapsulated tumour, being usually diagnosed in association with
an unerupted permanent maxillary canine [1,2]. There are scarce reports of
multiple AOTs [3–5] and a patient with Schimmelpenning syndrome (SS) with AOT
was reported [6]. SS is characterized by sebaceous nevi, associated with
ipsilateral abnormalities of the central nervous system, resulting from
postzygotic autosomal dominant HRAS or KRAS lethal mutations that survive by
somatic mosaicism [7].from #ORL via xlomafota13 on Inoreader
http://ift.tt/1YLbC7gvi...περισσότερα »
The linea aspera as a rotational landmark: an anatomical MRI-based study.
*The linea aspera as a rotational landmark: an
anatomical MRI-based study.*Surg Radiol Anat. 2016 Mar 12;Authors: Reple G,
Felden A, Feydy A, Anract P, Biau DAbstractPURPOSE: The linea aspera can be used
as a landmark to assess the rotation of the distal femoral epiphysis when
performing an endoprostheses. However, no study has assessed the reliability of
this landmark. We therefore asked whether the linea aspera could be used as a
rotational landmark for positioning distal femoral knee megaprostheses.
MATERIALS: This is an anatomic MRI-based study of 50 femurs (27 subjects).
...περισσότερα »
Personalized treatment of advanced non-small-cell lung cancer in routine clinical practice.
*Personalized treatment of advanced non-small-cell
lung cancer in routine clinical practice.*Cancer Metastasis Rev. 2016 Mar 12;
Authors: Pirker R, Filipits MAbstractPersonalized treatment of patients with
advanced non-small-cell lung cancer based on clinical and molecular tumor
features has entered clinical routine practice. The 2015 pathological
classification of lung cancer mandates immunohistochemical and molecular
analysis. Therapeutic strategies focused on inhibition of angiogenesis and
growth factor receptor signaling. Inhibitors of angiogenesis and monoclonal
antibodie...περισσότερα »
Morphological Continuum of mucocele like tumor with its Diagnostic Dilemmas – A Case Report with Cytohistological Correlation
AlexAndros SfakianakisστοMedicine by
Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel
:00302841026Πριν από 2 δευτερόλεπτα
2016-03-14T03-30-38Z*Source:* The Southeast Asian
Journal of Case Report and ReviewDr.Neelam Sood, Dr.Priyanka Bhatia Soni.
Introduction: A Mucocele-like tumor is a rare breast lesion, characterized by
mucin-filled cysts and extravasated mucin present in the adjacent stroma. First
described by Rosen as a benign entity, it is now considered as a continuum of
different pathological lesions, ranging from benign ductal hyperplasias ,
atypical ductal hyperplasia , ductal carcinoma in situ and mucinous carcinomas.
Case presentation: We describe a case of Mucocele like tumor of the
breas...περισσότερα »
Atmosphere, Vol. 7, Pages 45: Soot Nanoparticles Could Partake in Nucleation of Biogenic Particles in the Atmosphere: Using Fullerene as a Model Compound
The detection of existence of fullerenes (C60 and
C70) makes it necessary to explore whether soot nanoparticles can participate in
new nanometer-sized particle formation and growth in the atmosphere. This study
describes a theoretical investigation at multiple levels on the role of the
fullerenes (as model compounds to represent nanoparticles of soot) in the
formation of complexes with a common atmospheric nucleating precursor (sulfuric
acid, SA) and a biogenic organic acid (cis-pinonic acid, CPA), as well as
initial growth of nano-sized biogenic aerosols. Quantum chemical
density...περισσότερα »
Micromachines, Vol. 7, Pages 48: Experimental Analysis of Porosity and Permeability in Pressed Paper
In this paper, we report an analysis of pressed
paper in terms of porosity and permeability. Previously, we reported a pressed
paper that exhibits decreased porosity and permeability. Additionally, its
applications into programmed sample delivery as well as flow rate control were
reported. However, there is a need for a theoretical analysis of pressed paper
in terms of porosity and permeability for a more precise design principle and
its applications because porosity and permeability are important factors in
determining fluidic behavior. Here, we propose a theoretical model for
an...περισσότερα »
Assessment of fully-automated atlas-based segmentation of novel oral mucosal surface organ-at-risk.
*Assessment of fully-automated atlas-based
segmentation of novel oral mucosal surface organ-at-risk.*Radiother Oncol. 2016
Mar 9;Authors: Dean JA, Welsh LC, McQuaid D, Wong KH, Aleksic A, Dunne E, Islam
MR, Patel A, Patel P, Petkar I, Phillips I, Sham J, Newbold KL, Bhide SA,
Harrington KJ, Gulliford SL, Nutting CMAbstractBACKGROUND AND PURPOSE: Current
oral mucositis normal tissue complication probability models, based on the dose
distribution to the oral cavity volume, have suboptimal predictive power.
Improving the delineation of the oral mucosa is likely to improve these
...περισσότερα »
Assessment of fully-automated atlas-based segmentation of novel oral mucosal surface organ-at-risk.
*Assessment of fully-automated atlas-based
segmentation of novel oral mucosal surface organ-at-risk.*Radiother Oncol. 2016
Mar 9;Authors: Dean JA, Welsh LC, McQuaid D, Wong KH, Aleksic A, Dunne E, Islam
MR, Patel A, Patel P, Petkar I, Phillips I, Sham J, Newbold KL, Bhide SA,
Harrington KJ, Gulliford SL, Nutting CMAbstractBACKGROUND AND PURPOSE: Current
oral mucositis normal tissue complication probability models, based on the dose
distribution to the oral cavity volume, have suboptimal predictive power.
Improving the delineation of the oral mucosa is likely to improve these
...περισσότερα »
Personalized treatment of advanced non-small-cell lung cancer in routine clinical practice.
*Personalized treatment of advanced non-small-cell
lung cancer in routine clinical practice.*Cancer Metastasis Rev. 2016 Mar 12;
Authors: Pirker R, Filipits MAbstractPersonalized treatment of patients with
advanced non-small-cell lung cancer based on clinical and molecular tumor
features has entered clinical routine practice. The 2015 pathological
classification of lung cancer mandates immunohistochemical and molecular
analysis. Therapeutic strategies focused on inhibition of angiogenesis and
growth factor receptor signaling. Inhibitors of angiogenesis and monoclonal
antibodie...περισσότερα »
Shell-isolated nanoparticle-enhanced Raman spectroscopy study of the adsorption behaviour of DNA bases on Au(111) electrode surfaces
[image: CrossMark.jpg]*Analyst*, 2016, Accepted
Manuscript*DOI*: 10.1039/C6AN00180G, PaperBao-Ying Wen, Xi Jin, Yue Li, Ya-Hao
Wang, Chaoyu Li, Miao-Miao Liang, Rajapandiyan Panneerselvam, qingchi xu, De-Yin
Wu, Zhilin Yang, Jian-Feng Li, Zhong-qun TianFor the first time, we used
electrochemical shell-isolated nanoparticle-enhanced Raman spectroscopy
(EC-SHINERS) technique to in-situ characterize the adsorption behaviour of four
DNA bases (adenine, guanine, thymine, and cytosine) on atomically...The content
of this RSS Feed (c) The Royal Society of Chemistryfrom BioChemistry
...περισσότερα »
Rational control of nano-scale metal-catalysts for biomass conversion
[image: CrossMark.jpg]*Chem. Commun.*, 2016,
Accepted Manuscript*DOI*: 10.1039/C6CC00336B, Feature ArticleYunzhu Wang,
Sudipta De, Ning YanNano-scale metal particles have huge potential due to their
wide and diverse catalytic applications. Recently, they have shown numerous
applications in the field of biomass conversion. The proposed contribution is...
The content of this RSS Feed (c) The Royal Society of Chemistryfrom BioChemistry
via xlomafota13 on Inoreader http://ift.tt/1UseAwPvia IFTTT
Deposition, Patterning, and Utility of Conductive Materials for the Rapid Prototyping of Chemical and Bioanalytical Devices
[image: CrossMark.jpg]*Analyst*, 2016, Accepted
Manuscript*DOI*: 10.1039/C6AN00210B, MinireviewLeyla Soleymani, Christine
GabardoRapid prototyping is a critical step in the product development cycle of
miniaturized chemical and bioanalytical devices, often categorized as
lab-on-a-chip devices, biosensors, and micro-total analysis systems. While high
throughput...The content of this RSS Feed (c) The Royal Society of Chemistryfrom
BioChemistry via xlomafota13 on Inoreader http://ift.tt/1RhsBrFvia
IFTTT
Absence of Flexor Carpi Radialis during an Elective Carpometacarpal Arthroplasty of the Thumb: A Rare Anatomical Variation
Purpose. We present an extremely rare anatomical
variation of unilateral flexor carpi radialis (FCR) absence. This rare
anatomical variation posed a clinical dilemma to us and we highlight the
importance of the surgeon being aware of this anatomical variation of an
important structure both as a reconstruction tool and as an anatomical landmark.
Methods. This anatomical variation of the unilaterally absent FCR was found upon
dissection during a carpometacarpal arthroplasty of the thumb. Results. Upon the
discovery of an absent FCR tendon, we proceeded with a simple trapeziectomy.
C...περισσότερα »
The Genetics of Barrett's Esophagus: A Familial and Population-Based Perspective.
*The Genetics of Barrett's Esophagus: A Familial
and Population-Based Perspective.*Dig Dis Sci. 2016 Mar 12;Authors: To H,
Clemons NJ, Duong CP, Trainer AH, Phillips WAAbstractBarrett's esophagus (BE) is
intestinal metaplasia of the lower esophagus and a precursor lesion for
esophageal adenocarcinoma (EAC). Both are important health issues as they have
rising incidences in the Western world. Improving the management of BE relies on
understanding the underlying biology of this disease, but the exact biological
mechanisms have been difficult to determine. BE is generally though...περισσότερα »
HPV status is associated with altered PIWI-interacting RNA expression pattern in head and neck cancer
HPV status is associated with altered
PIWI-interacting RNA expression pattern in head and neck cancer: Head and neck
squamous cell carcinoma (HNSCC) affects over 550,000 patients worldwide each
year [1]. Tobacco and alcohol consumption, together with human papillomavirus
(HPV) infection are the main etiological factors [2–4]. Many studies have found
that patients with HPV-positive HNSCC have a better prognosis, with increased
survival and less chance of recurrence [5–7]. However, there have been
contradictory reports showing either no or poor associations with outcome.
Nevertheless, ...περισσότερα »
Atmosphere, Vol. 7, Pages 44: Weather and Tourism: Thermal Comfort and Zoological Park Visitor Attendance
medicinesfakianakisστοMedicine by
Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel
:00302841026182 & 00306932607174Πριν από 14 δευτερόλεπτα
Weather events have the potential to greatly
impact business operations and profitability, especially in outdoor-oriented
economic sectors such as Tourism, Recreation, and Leisure (TRL). Although a
substantive body of work focuses on the macroscale impacts of climate change,
less is known about how daily weather events influence attendance decisions,
particularly relating to the physiological thermal […]
Atmosphere, Vol. 7, Pages 45: Soot Nanoparticles Could Partake in Nucleation of Biogenic Particles in the Atmosphere: Using Fullerene as a Model Compound
medicinesfakianakisστοMedicine by
Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel
:00302841026182 & 00306932607174Πριν από 14 δευτερόλεπτα
The detection of existence of fullerenes
(C60 and C70) makes it necessary to explore whether soot nanoparticles can
participate in new nanometer-sized particle formation and growth in the
atmosphere. This study describes a theoretical investigation at multiple levels
on the role of the fullerenes (as model compounds to represent nanoparticles of
soot) in the formation […]
Atmosphere, Vol. 7, Pages 43: Reconstructing Fire Records from Ground-Based Routine Aerosol Monitoring
medicinesfakianakisστοMedicine by
Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel
:00302841026182 & 00306932607174Πριν από 14 δευτερόλεπτα
Long-term fire records are important to
understanding the trend of biomass burning and its interactions with air quality
and climate at regional and global scales. Traditionally, such data have been
compiled from ground surveys or satellite remote sensing. To obtain aerosol
information during a fire event to use in analyzing air quality, we propose a
[…]
Atmosphere, Vol. 7, Pages 44: Weather and Tourism: Thermal Comfort and Zoological Park Visitor Attendance
medicinesfakianakisστοMedicine by
Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel
:00302841026182 & 00306932607174Πριν από 14 δευτερόλεπτα
Weather events have the potential to greatly
impact business operations and profitability, especially in outdoor-oriented
economic sectors such as Tourism, Recreation, and Leisure (TRL). Although a
substantive body of work focuses on the macroscale impacts of climate change,
less is known about how daily weather events influence attendance decisions,
particularly relating to the physiological thermal […]
Atmosphere, Vol. 7, Pages 45: Soot Nanoparticles Could Partake in Nucleation of Biogenic Particles in the Atmosphere: Using Fullerene as a Model Compound
medicinesfakianakisστοMedicine by
Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel
:00302841026182 & 00306932607174Πριν από 14 δευτερόλεπτα
The detection of existence of fullerenes
(C60 and C70) makes it necessary to explore whether soot nanoparticles can
participate in new nanometer-sized particle formation and growth in the
atmosphere. This study describes a theoretical investigation at multiple levels
on the role of the fullerenes (as model compounds to represent nanoparticles of
soot) in the formation […]
Atmosphere, Vol. 7, Pages 43: Reconstructing Fire Records from Ground-Based Routine Aerosol Monitoring
medicinesfakianakisστοMedicine by
Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel
:00302841026182 & 00306932607174Πριν από 14 δευτερόλεπτα
Long-term fire records are important to
understanding the trend of biomass burning and its interactions with air quality
and climate at regional and global scales. Traditionally, such data have been
compiled from ground surveys or satellite remote sensing. To obtain aerosol
information during a fire event to use in analyzing air quality, we propose a
[…]
Researchers suggest blueberries could be used to fight Alzheimer’s
medicinesfakianakisστοMedicine by
Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel
:00302841026182 & 00306932607174Πριν από 14 δευτερόλεπτα
Two small-scale studies into the effects of
freeze-dried blueberry powder suggest that the berries could help improve brain
function and cognitive performance in some older adults. from
#Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader
http://ift.tt/1SMcEzh via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos
5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 &
00306932607174
Researchers suggest blueberries could be used to fight Alzheimer’s
medicinesfakianakisστοMedicine by
Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel
:00302841026182 & 00306932607174Πριν από 14 δευτερόλεπτα
Two small-scale studies into the effects of
freeze-dried blueberry powder suggest that the berries could help improve brain
function and cognitive performance in some older adults. from
#Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader
http://ift.tt/1SMcEzh via IFTTT
Pathologic Fracture in Osteosarcoma: Association with poorer overall survival
medicinesfakianakisστοMedicine by
Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel
:00302841026182 & 00306932607174Πριν από 14 δευτερόλεπτα
Publication date: Available online 14 March
2016 Source:European Journal of Surgical Oncology (EJSO) Author(s): Abhijeet
Ashok Salunke, Jaymin Shah, Nayan Gupta, Jyotindra Pandit from
#Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader
http://ift.tt/1RZgine via IFTTT
Cancers, Vol. 8, Pages 35: Mechanisms of Nuclear Export in Cancer and Resistance to Chemotherapy
medicinesfakianakisστοMedicine by
Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel
:00302841026182 & 00306932607174Πριν από 14 δευτερόλεπτα
Tumour suppressor proteins, such as p53,
BRCA1, and ABC, play key roles in preventing the development of a malignant
phenotype, but those that function as transcriptional regulators need to enter
the nucleus in order to function. The export of proteins between the nucleus and
cytoplasm is complex. It occurs through nuclear pores and exported proteins
[…]
Margin to tumor thickness ratio – A predictor of local recurrence and survival in oral squamous cell carcinoma
Margin to tumor thickness ratio – A predictor of
local recurrence and survival in oral squamous cell carcinoma: Surgical
resection is the mainstay of treatment for oral squamous cell carcinoma (OSCC).
Satisfactory oncologic resections require negative and adequate resection
margins. A microscopic margin of 5mm has traditionally been accepted as adequate
for various oral cavity sub-sites [1,2]. This definition, however, of adequate
surgical resection remains controversial as some authors propose 2mm to be
sufficient [3] while others advocate for more than 7mm [4]. Ch’ng et al. [5]
an...περισσότερα »
Toxicities and early outcomes in a phase 1 trial of photodynamic therapy for premalignant and early stage head and neck tumors
Toxicities and early outcomes in a phase 1 trial of
photodynamic therapy for premalignant and early stage head and neck tumors:
Photodynamic therapy (PDT) uses a photosensitizing agent and light to kill
cells, involving delivery of a photosensitizer or photosensitizer precursor
followed by illumination at a specific wavelength of light. The appeal of PDT in
oncology has been that photosensitizers such as Photofrin are retained in tumor
tissues for longer periods compared to normal tissue. The selectivity of
photosensitizer for diseased tissue, as well as the ability to target the
li...περισσότερα »
Assessment of voice, speech, and related quality of life in advanced head and neck cancer patients 10-years+ after chemoradiotherapy
Assessment of voice, speech, and related quality of
life in advanced head and neck cancer patients 10-years+ after
chemoradiotherapy: In patients with advanced head and neck cancer (HNC), both
the tumor and its treatment with combined chemoradiotherapy (CRT) can adversely
impact voice and speech outcomes. In patients with cancers of the oral cavity
and oropharynx, destructive effects of the tumor will mainly affect patients’
articulation and/or speech, whereas in laryngeal cancer patients, the tumor
often has negative effects on voice quality [1,2]. Treatment effects of (chemo-)
rad...περισσότερα »
Staging significance of bone invasion in small-sized (4cm or less) oral squamous cell carcinoma as defined by the American Joint Committee on Cancer
Staging significance of bone invasion in
small-sized (4cm or less) oral squamous cell carcinoma as defined by the
American Joint Committee on Cancer: According to the 2010 American Joint
Committee on Cancer (AJCC) [1], primary oral squamous cell carcinoma (OSCC)
patients with medullary bone invasion should be defined as T4a. Some studies
show that OSCC bone invasion has a significant effect on survival in univariate
analysis [2,3]. Furthermore, infiltrative bone invasion was shown to be
associated with patient prognosis after correcting for the effects of other
variables [4].
Evidence for a stabilization of incidence rates for base of tongue and tonsil carcinoma
Evidence for a stabilization of incidence rates for
base of tongue and tonsil carcinoma in the U.S. white population: Increasing
age-standardized incidence rates (ASIRs) for oropharyngeal (OP) squamous cell
carcinomas (SCC), have been reported using cancer registries in many western
countries, although the time periods and factors involved differ [1–4]. In East
Germany, however, ASIRs for OPSCC did not increase after 2008 (through 2011) for
males [4]. It was also noted [4] that previously rising ASIRs had stabilized
from 2000–2006 to 2007–2012 in Stockholm County, Sweden, for SCC of...περισσότερα »
Human papilloma virus and other biologic markers in nasopharyngeal cancer
Clinical implications of human papilloma virus and
other biologic markers in nasopharyngeal cancer: Human papilloma virus (HPV) is
associated with both the occurrence and prognosis of oropharyngeal cancer.
However, few studies have examined the relationship between HPV and
nasopharyngeal cancer (NPC). This study investigated the clinical implications
of HPV and other molecular markers, including p16, p53, and epidermal growth
factor receptor (EGFR), for NPC patients.
Salivary secretory leukocyte protease inhibitor (SLPI) and HNC
Salivary secretory leukocyte protease inhibitor
(SLPI) and head and neck cancer: The Cancer Prevention Study II Nutrition
Cohort: Head and neck cancer (HNC) is the eighth most common cancer worldwide
[1], arising in the epithelial lining of the oral cavity, pharynx, and larynx.
Lifestyle risk factors include tobacco and alcohol consumption, although human
papillomavirus (HPV) infection has recently emerged as a contributing factor,
especially at the oropharynx [2,3]. Although early-stage cancers have a
favorable prognosis, there are no reliable methods for the early detection of
HNC...περισσότερα »
Cetuximab in recurrent/metastatic disease of squamous cell carcinoma of head and neck
Emergence of long-term surviving patients with the
introduction of Cetuximab in recurrent/metastatic disease of squamous cell
carcinoma of head and neck: Approximately 30% of all patients diagnosed with
Squamous Cell Carcinoma of the Head and Neck (SCCHN) will ultimately have
recurrent disease or distant metastasis that render them unable to receive
radical treatment. Systemic palliative therapy is then the treatment of choice,
achieving a median overall survival of 10months with the combination of
chemotherapy (CT) and Cetuximab [1].
Polymorphous low-grade adenocarcinoma
Polymorphous low-grade adenocarcinoma: A Danish
national study: Polymorphous low-grade adenocarcinoma (PLGA) is a slow-growing
salivary gland malignancy with a non-aggressive behaviour [1]. PLGA is
predominantly found in females in their sixth to seventh decade, and it most
commonly arises in the minor salivary glands, with more than half of cases
involving the palate [2]. It can also occur in minor salivary glands in the rest
of the upper aero-digestive tract, as well as in major salivary glands [1,3].
PLGA accounts for approximately 25% of all intraoral malignant salivary gland
tu...περισσότερα »
RNA in-situ hybridization is a practical and effective method for determining HPV status of oropharyngeal squamous cell carcinoma including discordant cases that are p16 positive by immunohistochemistry but HPV negative by DNA in-situ hybridization
RNA in-situ hybridization is a practical and
effective method for determining HPV status of oropharyngeal squamous cell
carcinoma including discordant cases that are p16 positive by
immunohistochemistry but HPV negative by DNA in-situ hybridization: High-risk
human papillomavirus (HPV) has been confirmed as a causative agent in a subset
of head and neck squamous cell carcinomas characterized by origin from the
oropharynx, a unique demographic profile, and improved clinical outcomes
compared to non-HPV-related squamous cell carcinoma [1–4]. Accordingly, HPV
status has become a powerf...περισσότερα »
From flat into concave shape in soft tissue free flaps in oral cavity reconstruction: The origami technique
From flat into concave shape in soft tissue free
flaps in oral cavity reconstruction: The origami technique: The reconstruction
of the head and neck post oncological resection poses a challenge using
conventional methods. Flap reconstruction has become commonplace in these types
of reconstructions where it must accomplish and fulfil mainly seven purposes:
adequate wound coverage, prevention of infections, sealing of dead spaces,
functional restoration, provide enough volume to restore the entire defect,
protect the underlying structures during postoperative radiotherapy and lastly
p...περισσότερα »
Intra-operative radiation therapy (IORT) in recurrent head and neck cancer
Intra-operative radiation therapy (IORT) in
recurrent head and neck cancer: Intraoperative radiotherapy (IORT) an innovative
technique that assures the delivery of radiation immediately after surgical
resection and thus directly on tumor bed, without the necessity of excessive
radiation protection measures. The clinical data regarding the use of IORT in
head and neck cancer are little and a comprehensive and evidence-based analysis
of recurrent head and neck cancer is still pending. Despite an aggressive
multidisciplinary management, in head and neck cancer it is difficult to
achiev...περισσότερα »
Dendritic cells generated from peripheral blood monocytes (Mo-DCs) and stimulated with laryngeal cancer cell lysates are not good enough in stimulating anti-tumor immunity
Dendritic cells generated from peripheral blood
monocytes (Mo-DCs) and stimulated with laryngeal cancer cell lysates are not
good enough in stimulating anti-tumor immunity: The use of immunotherapy as an
adjuvant traditional treatment could prevent metastasis and give a chance for
longer survival of cancer patients. It is known that the dendritic cells are the
most effective antigen presenting cells (APC) and are the only APCs which
activate innate T cells, therefore, they may involve additional forces to attack
the cancerous cells [3]. The purpose of the use of immunotherapy is to
...περισσότερα »
Positive frozen section margins predict local recurrence in R0-resected squamous cell carcinoma of the head and neck
Positive frozen section margins predict local
recurrence in R0-resected squamous cell carcinoma of the head and neck: Initial
surgery with a clear resection of the primary tumour followed by adjuvant
radio-(chemo)therapy in advanced stages remains the gold standard therapy for
head neck squamous cell carcinoma [1–3]. Several former reports have emphasized
the importance of clear surgical margins for recurrence-free and
disease-specific survival [4–6]. In discussion however is the optimal width of
surgical margins. Currently resection margins are mostly categorized in involved
(<1mm),...περισσότερα »
Recurrent G12V pathogenic mutation in adenomatoid odontogenic tumours
Recurrent G12V pathogenic mutation in adenomatoid
odontogenic tumours: The adenomatoid odontogenic tumour (AOT) is a
non-aggressive encapsulated tumour, being usually diagnosed in association with
an unerupted permanent maxillary canine [1,2]. There are scarce reports of
multiple AOTs [3–5] and a patient with Schimmelpenning syndrome (SS) with AOT
was reported [6]. SS is characterized by sebaceous nevi, associated with
ipsilateral abnormalities of the central nervous system, resulting from
postzygotic autosomal dominant HRAS or KRAS lethal mutations that survive by
somatic mosaicism...περισσότερα »
Rhinosinusal Inflammation and High Mobility Group Box 1 Protein: A New Target for Therapy
Rhinosinusal Inflammation and High Mobility Group
Box 1 Protein: A New Target for Therapy: *Background/Aims:* High mobility group
box 1 (HMGB1) is a protein belonging to the class of damage-associated molecular
pattern molecules, which activates innate immunity and powerful inflammatory
factors. The aim of this review is to show the importance of HMGB1 in the
pathogenesis of nasal inflammatory diseases and to suggest that inhibition of
HMGB1 may be an innovative therapeutic target. *Methods:* We used
immunohistochemistry to study whether HMGB1 increases in chronic rhinosinusitis
wit...περισσότερα »
AOSpine Masters Series, Volume 4: Adult Spinal Deformities, Luiz Roberto Vialle, Lawrence G. Lenke, Kenneth M.C. Cheung. Thieme, New York, NY (2015)
otolaryngologistsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.Alexandros,,Anapafseos 5 Agios
Nikolaos 72100 Crete Greece,tel : 00302841026182,00306932607174Πριν
από 18 δευτερόλεπτα
Publication date: May 2016 Source:World
Neurosurgery, Volume 89 Author(s): Daniel M. Sciubba from #ORL-Sfakianakis via
xlomafota13 on Inoreader http://ift.tt/24ZzDvt via IFTTT
Family with hearing loss accompanied by compound heterozygous mutations in LOXHD1
Clinical characteristics of a Japanese via Auris
Nasus LarynxPublication date: Available online 10 March 2016*Source:*Auris Nasus
LarynxAuthor(s): Shujiro B. Minami, Hideki Mutai, Kazunori Namba, Hirozazu
Sakamoto, Tatsuo MatsunagaObjectiveTo report two novel LOXHD1 mutations,
including missense mutations and the clinical features of the patients.MethodsWe
studied a three-generation Japanese family with hearing loss. Targeted
next-generation sequencing was used for genetic analysis. Conditional
orientation response audiometry and pure tone audiometry were used to assess
hearing. ...περισσότερα »
Er:Yag Laser Treatment of Simple Snorers in an Outpatient Setting
Er:Yag Laser Treatment of Simple Snorers in an
Outpatient Setting: *Objective:* Snoring occurs as a result of soft tissue
vibration caused by a partial upper airway collapse during sleep. This study
evaluated the effectiveness and potential adverse side effects associated with
the use of a nonsurgical, erbium-doped yttrium aluminum garnet (Er:YAG) laser
treatment for patients with snoring conditions. *Materials and Methods:* In
total, 33 patients with different degrees of snoring were analyzed
retrospectively. All patients received three NightLase™ Er:YAG laser treatments.
Results w...περισσότερα »
An Imaging Study in Patients With Thyroid Cancer or Head and Neck Cancer With Pertechnetate Made in a Cyclotron (C-PERT)
An Imaging Study in Patients With Thyroid Cancer or
Head and Neck Cancer With Pertechnetate Made in a Cyclotron (C-PERT):
*Conditions*: Thyroid Neoplasms; Head and Neck Neoplasms*Interventions*:
Drug: C-PERT; Drug: G-PERT*Sponsors*: AHS Cancer Control Alberta; Cross
Cancer InstituteDoctors at the Cross Cancer Institute have developed a new
method of producing 99mTc Pertechnetate in a cyclotron unit. A study done at the
Cross Cancer Institute in 2011 with ten patients using this imaging agent showed
that it was safe and produced images with the same pattern as gener...περισσότερα »
Reference-Free Assessment of Speech Intelligibility Using Bispectrum of an Auditory Neurogram
Reference-Free Assessment of Speech Intelligibility
Using Bispectrum of an Auditory Neurogram: Sensorineural hearing loss occurs due
to damage to the inner and outer hair cells of the peripheral auditory system.
Hearing loss can cause decreases in audibility, dynamic range, frequency and
temporal resolution of the auditory system, and all of these effects are known
to affect speech intelligibility. In this study, a new reference-free speech
intelligibility metric is proposed using 2-D neurograms constructed from the
output of a computational model of the auditory periphery. The resp...περισσότερα »
Long-term Voice Outcomes of Early Thyroplasty for Unilateral Vocal Fold Paralysis Following Aortic Arch Surgery
Long-term Voice Outcomes of Early Thyroplasty for
Unilateral Vocal Fold Paralysis Following Aortic Arch Surgery: Objective:To
describe this institution’s experience with and the long-term outcomes of early
type 1 thyroplasty for unilateral vocal fold paralysis (UVFP) following surgery
on the aortic arch.Study Design:Retrospective chart review with telephone
questionnaire.Setting:Academic tertiary care center.Subjects and Methods:Three
hundred forty-eight patients with UVFP following surgery on the aortic arch
since 1999 were identified; 40 were available for follow-up. Th...περισσότερα »
Compound Motor Action Potential Quantifies Recurrent Laryngeal Nerve Innervation in a Canine Model
Compound Motor Action Potential Quantifies
Recurrent Laryngeal Nerve Innervation in a Canine Model: Objective:The compound
motor action potential (CMAP) is the summated action potential from multiple
muscle fibers activated by a single nerve impulse. The utility of laryngeal
muscle CMAP for quantifying innervation following recurrent laryngeal nerve
(RLN) injury was investigated.Method:In a series of 21 canine hemi-laryngeal
preparations, RLNs were exposed and a stimulating electrode placed. Maximum CMAP
amplitudes and area under the curve from the thyroarytenoid (TA) muscles
we...περισσότερα »
Effects of steam inhalation on voice quality-related acoustic measures
Effects of steam inhalation on voice
quality-related acoustic measures: Objectives/HypothesisTo investigate the
effects of steam inhalation using a facial steamer on voice quality-related
acoustic measures.Study DesignProspective outcome research: single-blinded
experimental study.MethodsForty-five vocally healthy female subjects ranging in
age from 18 to 30 years (Mean age: 22.41 years; standard deviation [SD]: 8.91)
participated in the study. Phonation samples were recorded under three different
conditions in triplicate: baseline recording, immediately after mouth breathing
(d...περισσότερα »
Bilateral vestibulopathy
Diverse clinical and laboratory manifestations of
bilateral vestibulopathy: Objectives/HypothesisTo identify the clinical and
laboratory characteristics of bilateral vestibulopathy (BVP) on the video head
impulse test (vHIT).Study DesignRetrospective chart analysis.MethodsDuring 23
months, 1,789 patients with dizziness underwent vHIT in our tertiary referral
hospital. Of these patients, 65 (3.6%) patients had bilaterally positive
catch-up saccades. Based on the caloric test, 15 (group 1) had bilateral caloric
weakness, 13 (group 2) had unilateral caloric weakness, and 37 (group
...περισσότερα »
Effect of vocal fold asymmetries on glottal flow
Effect of vocal fold asymmetries on glottal flow:
Objectives/HypothesisVoice disorders, such as unilateral vocal fold paralysis or
paresis, and vocal fold scarring feature structural asymmetries of the vocal
folds. Studies on how structural asymmetries affect voice has mostly been
limited to computational simulations and experiments on mechanical models. The
purpose of the current study is to examine the effects of asymmetries in
left–right position, height, and length of the vocal folds on the intraglottal
flow characteristics, as well as acoustics in the canine larynx model.
Stu...περισσότερα »
Predictors of survival in parotid small cell carcinoma
Predictors of survival in parotid small cell
carcinoma: A study of 344 cases: [image:
cover.gif?v=1&s=91b5c09aa476055defd12367]Objectives/HypothesisWe sought
to better characterize patient, tumor, and long-term survival characteristics of
parotid small cell carcinoma (SmCC) with the National Cancer Database (NCDB).
Study DesignRetrospective database review.MethodsWe reviewed the NCDB
(1998–2012) for all cases of parotid SmCC. Relevant demographic, tumor, and
survival variables were extracted and analyzed. Cox multivariate regression was
performed to identify prognosticators....περισσότερα »
External bioresorbable airway rigidification to treat refractory localized tracheomalacia
External bioresorbable airway rigidification
to treat refractory localized tracheomalacia: [image:
cover.gif?v=1&s=91b5c09aa476055defd12367]Objectives/HypothesisOur study
evaluates the efficacy of extraluminal bioresorbable plates to treat refractory
localized airway malacia in patients undergoing corrective surgery for complex
multilevel laryngotracheal stenosis.Study DesignRetrospective case series.
MethodsSecondary malacic airway segments were characterized (severity, site,
type) by a dynamic transnasal flexible laryngotracheobronchoscopy before
surgery. Extraluminal bior...περισσότερα »
Cutaneous facial defects
An innovative photographic database for
cutaneous facial defects: [image:
cover.gif?v=1&s=91b5c09aa476055defd12367]Objectives/HypothesisTo
construct an easy-to-use server-based database that stores photographs of
patients undergoing reconstructive surgery for cutaneous facial defects and
organizes them in a manner best suited for rapid search and education.Study
DesignAn institutional review board-approved user-modifiable database was
designed using OnBase software (Hyland Software Inc., Westlake, OH) to store
both the photographs of patients undergoing reconstructive surgery ...περισσότερα »
Percutaneous steroid injection for treating benign vocal fold lesions: A prospective study
Long-term efficacy of percutaneous steroid
injection for treating benign vocal fold lesions: A prospective study:
Objectives/HypothesisThis study assessed the long-term efficacy and recurrence
rates of percutaneous steroid injections (PSIs) for benign vocal fold lesions.
Study DesignProspective clinical study.MethodsA prospective human clinical trial
was performed from October 2008 to September 2014 at Soonchunhyang University
Hospital, Bucheon, Korea. Percutaneous steroid injection was performed in 84
consecutive patients with small benign vocal fold lesions, such as vocal fold
...περισσότερα »
Clinical risk assessment model for pediatric obstructive sleep apnea
Clinical risk assessment model for pediatric
obstructive sleep apnea: [image:
cover.gif?v=1&s=91b5c09aa476055defd12367]Objectives/HypothesisTo develop
a clinical risk prediction model that identifies children with obstructive sleep
apnea (OSA) in a clinical setting by examining the symptoms, physical status,
and OSA-18 questionnaire results.DesignSingle institutional, cross-sectional
study.MethodsChildren aged 2 to 18 years with symptoms of OSA were enrolled.
Pediatric OSA was diagnosed through full-night polysomnography. Clinical data,
namely demographics, symptoms, OSA-18 ...περισσότερα »
Practice variations in voice treatment selection following vocal fold mucosal resection
Practice variations in voice treatment
selection following vocal fold mucosal resection: [image:
cover.gif?v=1&s=91b5c09aa476055defd12367]Objectives/HypothesisTo
characterize initial voice treatment selection following vocal fold mucosal
resection in a Medicare population.Study DesignRetrospective analysis of a
large, nationally representative Medicare claims database.MethodsPatients with
> 12 months of continuous Medicare coverage who underwent a leukoplakia-
or cancer-related vocal fold mucosal resection (index) procedure during calendar
years 2004 to 2009 were studied. T...περισσότερα »
First results of a novel adjustable-length ossicular reconstruction prosthesis in temporal bones
First results of a novel adjustable-length
ossicular reconstruction prosthesis in temporal bones: [image:
cover.gif?v=1&s=91b5c09aa476055defd12367]Objectives/HypothesisThe
performance of an ossicular replacement prosthesis (ORP) is influenced by its
alignment and appropriate tension between the tympanic membrane and the stapes
footplate. A novel ORP with a flexible element that potentially allows for
length adjustment in situ is presented and tested for acoustic performance.Study
DesignLaser Doppler vibrometry in fresh human cadaveric temporal bones was used
to test the acou...περισσότερα »
Effect of saline inhalation on vocal fold epithelial morphology evaluated by optical coherence tomography
Effect of saline inhalation on vocal fold
epithelial morphology evaluated by optical coherence tomography: [image:
cover.gif?v=1&s=91b5c09aa476055defd12367]Objectives/Hypothesis
Examination of tissue structures by optical coherence tomography (OCT) has been
shown to be useful on mucous membranes of the vocal folds, but so far its
application to the human larynx has been limited because it is technically
cumbersome and usually needs to be performed with sedation. Here a newly
developed, noninvasive combined laryngoscopy and OCT procedure is described and
its suitability for ambu...περισσότερα »
Propensity score analysis of endoscopic and open approaches to malignant paranasal and anterior skull base tumor outcomes
Propensity score analysis of endoscopic and open
approaches to malignant paranasal and anterior skull base tumor outcomes:
Objectives/HypothesisMalignant sinonasal and skull base tumors are now being
resected using an endoscopic technique, but there has been controversy regarding
the oncologic safety of this approach. Various studies have compared the
outcomes from endoscopic surgery to those from open techniques; however, all
have been limited by substantial differences in the patient populations
receiving each approach. In this study we compare outcomes of open and
endoscopic te...περισσότερα »
The ototronix MAXUM middle ear implant for severe high-frequency sensorineural hearing loss: Preliminary results
The ototronix MAXUM middle ear implant for
severe high-frequency sensorineural hearing loss: Preliminary results: [image:
cover.gif?v=1&s=91b5c09aa476055defd12367]Objectives/HypothesisTo report
the preliminary results of the Ototronix MAXUM middle ear implant for treatment
of severe high-frequency sensorineural hearing loss.Study DesignCase series with
chart review.MethodsSix consecutive ears with severe high-frequency
sensorineural hearing loss (≥75 dB HL at 2, 3, and 4 kHz) and poor aided word
recognition performance (≤60% single words) underwent implantation of the MAXUM
...περισσότερα »
Sialendoscopy-assisted surgery and the chronic obstructive sialadenitis symptoms questionnaire: A prospective study
Sialendoscopy-assisted surgery and the
chronic obstructive sialadenitis symptoms questionnaire: A prospective study:
[image: cover.gif?v=1&s=91b5c09aa476055defd12367]Objectives/HypothesisTo
prospectively assess symptoms of obstructive sialadenitis before and after
sialendoscopy-assisted salivary duct surgery (SASDS) using the chronic
obstructive sialadenitis symptoms (COSS) questionnaire to determine and predict
impact of interventions.Study DesignProspective cohort study.MethodsAdult
patients with chronic obstructive sialadenitis who underwent SASDS were asked to
complete ...περισσότερα »
The efficacy of combination therapy for idiopathic sudden sensorineural hearing loss
The efficacy of combination therapy for
idiopathic sudden sensorineural hearing loss: [image:
cover.gif?v=1&s=91b5c09aa476055defd12367]Objectives/HypothesisThe aim of
this study was to compare the hearing results of patients with idiopathic sudden
sensorineural hearing loss (ISSNHL) who initially were treated with either a
combination therapy of systemic steroids (SS) and intratympanic steroid
injection (IT-S) or SS only.MethodsThe study followed a retrospective
case-control design. One-hundred five patients who were diagnosed with ISSNHL
and required treatment via admission...περισσότερα »
Nonstimulated rabbit phonation model: Cricothyroid approximation
Nonstimulated rabbit phonation model:
Cricothyroid approximation: [image:
cover.gif?v=1&s=91b5c09aa476055defd12367]Objectives/HypothesisTo
describe a nonstimulated in vivo rabbit phonation model using an Isshiki type IV
thyroplasty and uninterrupted humidified glottal airflow to produce sustained
audible phonation.Study DesignProspective animal study.MethodsSix New Zealand
white breeder rabbits underwent a surgical procedure involving an Isshiki type
IV thyroplasty and continuous airflow delivered to the glottis. Phonatory
parameters were examined using high-speed laryngeal...περισσότερα »
Cancers, Vol. 8, Pages 35: Mechanisms of Nuclear Export in Cancer and Resistance to Chemotherapy
Tumour suppressor proteins, such as p53, BRCA1, and
ABC, play key roles in preventing the development of a malignant phenotype, but
those that function as transcriptional regulators need to enter the nucleus in
order to function. The export of proteins between the nucleus and cytoplasm is
complex. It occurs through nuclear pores and exported proteins need a nuclear
export signal (NES) to bind to nuclear exportin proteins, including CRM1
(Chromosomal Region Maintenance protein 1), and the energy for this process is
provided by the RanGTP/RanGDP gradient. Due to the loss of DNA repa...περισσότερα »
Acute trauma factor associations with suicidality across the first 5 years after traumatic brain injury
Alexandros G. SfakianakisστοRehabilitation,Sports and Exercise Medicine by Alexandros G.
SfakianakisΠριν από 22 δευτερόλεπτα
Publication date: Available online 14 March 2016
*Source:*Archives of Physical Medicine and RehabilitationAuthor(s): Matthew R.
Kesinger, Shannon B. Juengst, Hillary Bertisch, Janet P. Niemeier, Jason W.
Krellman, Mary Jo Pugh, Raj G. Kumar, Jason L. Sperry, Patricia M. Arenth, Jesse
R. Fann, Amy K. WagnerObjectiveTo determine whether severities of head and
extra-cranial injuries (ECI) were associated with suicidal ideation (SI) or
suicide attempt (SA) after traumatic brain injury (TBI).DesignFactors associated
with SI and SA were assessed in this inception cohort study using data
...περισσότερα »
Toxics, Vol. 4, Pages 7: Urinary Phthalate Metabolites and Biomarkers of Oxidative Stress in a Mexican-American Cohort: Variability in Early and Late Pregnancy
Alexandros G. SfakianakisστοNews in OtoRhinoLaryngology -
Alexandros G. SfakianakisΠριν από 22 δευτερόλεπτα
People are exposed to phthalates through their wide
use as plasticizers and in personal care products. Many phthalates are endocrine
disruptors and have been associated with adverse health outcomes. However,
knowledge gaps exist in understanding the molecular mechanisms associated with
the effects of exposure in early and late pregnancy. In this study, we examined
the relationship of eleven urinary phthalate metabolites with isoprostane, an
established marker of oxidative stress, among pregnant Mexican-American women
from an agricultural cohort. Isoprostane levels were on average 2...περισσότερα »
Atmosphere, Vol. 7, Pages 45: Soot Nanoparticles Could Partake in Nucleation of Biogenic Particles in the Atmosphere: Using Fullerene as a Model Compound
Alexandros G. SfakianakisστοNews in OtoRhinoLaryngology -
Alexandros G. SfakianakisΠριν από 22 δευτερόλεπτα
The detection of existence of fullerenes (C60 and
C70) makes it necessary to explore whether soot nanoparticles can participate in
new nanometer-sized particle formation and growth in the atmosphere. This study
describes a theoretical investigation at multiple levels on the role of the
fullerenes (as model compounds to represent nanoparticles of soot) in the
formation of complexes with a common atmospheric nucleating precursor (sulfuric
acid, SA) and a biogenic organic acid (cis-pinonic acid, CPA), as well as
initial growth of nano-sized biogenic aerosols. Quantum chemical
density...περισσότερα »
Micromachines, Vol. 7, Pages 48: Experimental Analysis of Porosity and Permeability in Pressed Paper
Alexandros G. SfakianakisστοNews in OtoRhinoLaryngology -
Alexandros G. SfakianakisΠριν από 22 δευτερόλεπτα
In this paper, we report an analysis of pressed
paper in terms of porosity and permeability. Previously, we reported a pressed
paper that exhibits decreased porosity and permeability. Additionally, its
applications into programmed sample delivery as well as flow rate control were
reported. However, there is a need for a theoretical analysis of pressed paper
in terms of porosity and permeability for a more precise design principle and
its applications because porosity and permeability are important factors in
determining fluidic behavior. Here, we propose a theoretical model for
an...περισσότερα »
Acute trauma factor associations with suicidality across the first 5 years after traumatic brain injury
Alexandros G. SfakianakisστοNews in OtoRhinoLaryngology -
Alexandros G. SfakianakisΠριν από 22 δευτερόλεπτα
Publication date: Available online 14 March 2016
*Source:*Archives of Physical Medicine and RehabilitationAuthor(s): Matthew R.
Kesinger, Shannon B. Juengst, Hillary Bertisch, Janet P. Niemeier, Jason W.
Krellman, Mary Jo Pugh, Raj G. Kumar, Jason L. Sperry, Patricia M. Arenth, Jesse
R. Fann, Amy K. WagnerObjectiveTo determine whether severities of head and
extra-cranial injuries (ECI) were associated with suicidal ideation (SI) or
suicide attempt (SA) after traumatic brain injury (TBI).DesignFactors associated
with SI and SA were assessed in this inception cohort study using data
...περισσότερα »
Serum uric acid levels during leprosy reaction episodes
Alexandros G. SfakianakisστοNews in OtoRhinoLaryngology -
Alexandros G. SfakianakisΠριν από 22 δευτερόλεπτα
Background. Leprosy reactions are acute
inflammatory episodes that occur mainly in the multibacillary forms of the
disease. The reactions are classified as type 1 (reverse reaction) or type 2
(erythema nodosum leprosum). Leprosy-associated oxidative stress has been widely
demonstrated. Several recent studies have shown uric acid (UA) to have
antioxidative effects under pathologic conditions. The objective of this study
was to assess serum levels of UA in patients with leprosy reactions, with the
aim of monitoring their levels before and after treatment, compared with levels
in lep...περισσότερα »
Reproductive biology of the biofuel plant Jatropha curcas in its center of origin
Alexandros G. SfakianakisστοNews in OtoRhinoLaryngology -
Alexandros G. SfakianakisΠριν από 22 δευτερόλεπτα
In this work, we studied the main characteristics
of flowering, reproductive system and diversity of pollinators for the biofuel
plant Jatropha curcas (L.) in a site of tropical southeastern Mexico, within its
center of origin. The plants were monoecious with inflorescences of unisexual
flowers. The male flowers produced from 30625016 pollen grains (266–647 per
anther). The plants produced fruits with both geitonogamy and xenogamy, although
insect pollination significantly increased the number and quality of fruits. A
high diversity of flower visiting insects (36 species) was foun...περισσότερα »
Reducing bias in population and landscape genetic inferences: the effects of sampling related individuals and multiple life stages
Alexandros G. SfakianakisστοNews in OtoRhinoLaryngology -
Alexandros G. SfakianakisΠριν από 22 δευτερόλεπτα
In population or landscape genetics studies, an
unbiased sampling scheme is essential for generating accurate results, but
logistics may lead to deviations from the sample design. Such deviations may
come in the form of sampling multiple life stages. Presently, it is largely
unknown what effect sampling different life stages can have on population or
landscape genetic inference, or how mixing life stages can affect the parameters
being measured. Additionally, the removal of siblings from a data set is
considered best-practice, but direct comparisons of inferences made with and
wit...περισσότερα »
The effect of ribosomal protein S15a in lung adenocarcinoma
Alexandros G. SfakianakisστοNews in OtoRhinoLaryngology -
Alexandros G. SfakianakisΠριν από 22 δευτερόλεπτα
Background: RPS15A (Ribosomal Protein S15A)
promotes mRNA/ribosome interactions in translation. It is critical for the
process of eukaryotic protein biosynthesis. Recently, aberrantly expressed
RPS15A was found in the hepatitis virus and in malignant tumors. However, the
role of RPS15A has not been fully revealed on the development of lung cancer.
Method: In this study, a Tissue Microarray (TMA) of primary lung adenocarcinoma
tissue specimens was carried out. Furthermore, to further investigate the
function of RPS15A in lung cancer, RPS15A-specific short hairpin RNA (shRNA)
expres...περισσότερα »
The role of sex and age in the architecture of intrapopulation howler monkey-plant networks in continuous and fragmented rain forests
Alexandros G. SfakianakisστοNews in OtoRhinoLaryngology -
Alexandros G. SfakianakisΠριν από 22 δευτερόλεπτα
We evaluated the structure of intrapopulation
howler monkey-plant interactions by focusing on the plant species consumed by
different sex and age classes in continuous and fragmented forests in southern
Mexico. For this we used network analysis to evaluate the impact of
fragmentation on howler population traits and on resource availability and food
choice. A total of 37 tree and liana species and seven plant items (bark,
immature fruits, flowers, mature fruits, immature leaves, mature leaves and
petioles) were consumed, but their relative consumption varied according to sex
and ag...περισσότερα »
Palatability and pharmacokinetics of flunixin when administered to sheep through feed
Alexandros G. SfakianakisστοNews in OtoRhinoLaryngology -
Alexandros G. SfakianakisΠριν από 22 δευτερόλεπτα
Applying analgesics to feed is a potentially easy
method of providing pain-relief to sheep and lambs that undergo painful
husbandry procedures. To be effective, the medicated feed needs to be readily
accepted by sheep and its consumption needs to result in therapeutic
concentrations of the drug. In the present experiment, pelleted feed was
supplemented with flunixin (4.0 mg/kg live weight) and offered to eight sheep.
To test the palatability of flunixin, the individually penned sheep were offered
normal feed and feed supplemented with flunixin in separate troughs for two
consecuti...περισσότερα »
A new species of Psychrophrynella (Amphibia, Anura, Craugastoridae) from the humid montane forests of Cusco, eastern slopes of the Peruvian Andes
Alexandros G. SfakianakisστοNews in OtoRhinoLaryngology -
Alexandros G. SfakianakisΠριν από 22 δευτερόλεπτα
We describe a new species of Psychrophrynella from
the humid montane forest of the Department Cusco in Peru. Specimens were
collected at 2,670–3,165 m elevation in the Área de Conservación Privada Ukumari
Llakta, Japumayo valley, near Comunidad Campesina de Japu, in the province of
Paucartambo. The new species is readily distinguished from all other species of
Psychrophrynella but P. bagrecito and P. usurpator by possessing a tubercle on
the inner edge of the tarsus, and from these two species by its yellow ventral
coloration on abdomen and limbs. Furthermore, the new species is l...περισσότερα »
Scientific publications in nursing journals from Mainland China, Taiwan, and Hong Kong: a 10-year survey of the literature
Alexandros G. SfakianakisστοNews in OtoRhinoLaryngology -
Alexandros G. SfakianakisΠριν από 22 δευτερόλεπτα
Background: China has witnessed remarkable progress
in scientific performance in recent years. However, the quantity and quality of
nursing publications from three major regions (Mainland China, Taiwan, and Hong
Kong) have not been reported. This study aimed to investigate the
characteristics of scientific research productivity from Mainland China, Taiwan,
and Hong Kong in the field of nursing. Methods: Articles published in the 110
nursing journals originating from Mainland China, Taiwan, and Hong Kong between
2005 and 2014 were retrieved from the Web of Science. The total
number...περισσότερα »
ColoFinder: a prognostic 9-genes signature improve prognosis for 871 stage II and III colorectal cancer patients
Alexandros G. SfakianakisστοNews in OtoRhinoLaryngology -
Alexandros G. SfakianakisΠριν από 22 δευτερόλεπτα
Colorectal cancer (CRC) is the heterogeneous
disease with a high mortality rate, and still lacks an effective treatment. Our
goal is to develop a robust prognosis model for predicting the prognosis in CRC
patients. In this study, 871 stage II and III CRC samples were collected from
six gene expression profilings. ColoFinder was developed using 9-genes signature
based Random Survival Forest (RSF) prognosis model. The 9-genes signature
recurrence score was derived with 5-fold cross validation to test the
association with relapse-free survival and the value of AUC was gained with
0.8...περισσότερα »
Computational inference of H3K4me3 and H3K27ac domain length
Alexandros G. SfakianakisστοNews in OtoRhinoLaryngology -
Alexandros G. SfakianakisΠριν από 22 δευτερόλεπτα
Background. Recent epigenomic studies have shown
that the length of a DNA region covered by an epigenetic mark is not just a
byproduct of the assaying technologies and has functional implications for that
locus. For example, expanded regions of DNA sequences that are marked by
enhancer-specific histone modifications, such as acetylation of histone H3
lysine 27 (H3K27ac) domains coincide with cell-specific enhancers, known as
super or stretch enhancers. Similarly, promoters of genes critical for
cell-specific functions are marked by expanded H3K4me3 domains in the cognate
cell type...περισσότερα »
Biosensors, Vol. 6, Pages 8: Aryl Diazonium Chemistry for the Surface Functionalization of Glassy Biosensors
Alexandros G. SfakianakisστοNews in OtoRhinoLaryngology -
Alexandros G. SfakianakisΠριν από 22 δευτερόλεπτα
Nanostring resonator and fiber-optics-based
biosensors are of interest as they offer high sensitivity, real-time
measurements and the ability to integrate with electronics. However, these
devices are somewhat impaired by issues related to surface modification. Both
nanostring resonators and photonic sensors employ glassy materials, which are
incompatible with electrochemistry. A surface chemistry approach providing
strong and stable adhesion to glassy surfaces is thus required. In this work, a
diazonium salt induced aryl film grafting process is employed to modify a novel
SiCN gla...περισσότερα »
A hepatitis C virus envelope polymorphism confers resistance to neutralization by polyclonal sera and broadly neutralizing monoclonal antibodies
Alexandros G. SfakianakisστοNews in OtoRhinoLaryngology -
Alexandros G. SfakianakisΠριν από 22 δευτερόλεπτα
Journal of Virologyfrom #Medicine via ola Kala on
Inoreader http://ift.tt/1pGbASevia IFTTT
Efficacy of direct-acting antiviral combination for patients with HCV genotype 1 infection and severe renal impairment or end-stage renal disease
Alexandros G. SfakianakisστοNews in OtoRhinoLaryngology -
Alexandros G. SfakianakisΠριν από 22 δευτερόλεπτα
Gastroenterologyfrom #Medicine via ola Kala on
Inoreader http://ift.tt/22f0nWKvia IFTTT
Elevated serum gamma-glutamyltransferase predicts advanced histological liver damage in chronic hepatitis b
Alexandros G. SfakianakisστοNews in OtoRhinoLaryngology -
Alexandros G. SfakianakisΠριν από 22 δευτερόλεπτα
Discovery Medicinefrom #Medicine via ola Kala on
Inoreader http://ift.tt/1pGbAS8via IFTTT
Colectomy rates in patients with ulcerative colitis following treatment with infliximab or ciclosporin: a systematic literature review
Alexandros G. SfakianakisστοNews in OtoRhinoLaryngology -
Alexandros G. SfakianakisΠριν από 22 δευτερόλεπτα
European Journal of Gastroenterology &
Hepatologyfrom #Medicine via ola Kala on Inoreader http://ift.tt/22f0nWwvia
IFTTT
Multidrug resistance protein 4 is a critical protein associated with the antiviral efficacy of nucleos(t)ide analogues
Alexandros G. SfakianakisστοNews in OtoRhinoLaryngology -
Alexandros G. SfakianakisΠριν από 22 δευτερόλεπτα
Liver Internationalfrom #Medicine via ola Kala on
Inoreader http://ift.tt/1pGbARXvia IFTTT
AOSpine Masters Series, Volume 4: Adult Spinal Deformities, Luiz Roberto Vialle, Lawrence G. Lenke, Kenneth M.C. Cheung. Thieme, New York, NY (2015)
[image: alertIcon.gif]Publication date: May 2016
*Source:*World Neurosurgery, Volume 89Author(s): Daniel M. Sciubbafrom Neurology
via xlomafota13 on Inoreader http://ift.tt/24ZzDvtvia IFTTT
Interactions of subglottal pressure and neuromuscular activation on fundamental frequency and intensity
Interactions of subglottal pressure and
neuromuscular activation on fundamental frequency and intensity:
Objectives/HypothesisFundamental frequency (F0) and intensity sound pressure
level (SPL) of voice are controlled by intrinsic laryngeal muscle (ILM)
activation and subglottal pressure (Psub). Their interactions were investigated.
MethodsIn an in vivo canine model, the thyroarytenoid (TA), lateral
cricoarytenoid/interarytenoid (LCA/IA), and cricothyroid (CT) muscles were
independently activated from threshold to maximal contraction by neuromuscular
stimulation in various combina...περισσότερα »
Necrotizing Periodontal Diseases in Children
Necrotizing Periodontal Diseases in Children: A
Literature Review and Adjustment of Treatment.:J Trop Pediatr. 2016 Mar 10;
Authors: Marty BM, Palmieri J, Noirrit-Esclassan E, Vaysse F, Bailleul-Forestier
IAbstractNecrotizing ulcerative gingivitis, sometimes observed in young
children, may lead to necrotizing stomatitis and noma. Therefore, its
interception is a necessity and a challenge for the paediatric practitioners.
First, this article aims to propose a systematic review of recent literature on
the use of local antiseptic and antibiotic prescription in this particular
per...περισσότερα »
Postoperative Oral Fluid Intake as a Predictor of Postoperative Emergency Department Visits After Pediatric Tonsillectomy.
Investigation of Postoperative Oral Fluid Intake as
a Predictor of Postoperative Emergency Department Visits After Pediatric
Tonsillectomy.:JAMA Otolaryngol Head Neck Surg. 2016 Mar 10;Authors: Rohlfing
ML, Wistermayer PR, Bungo TM, Mims JW, Kirse DJAbstractImportance: This study
contributes novel data on the association between oral fluid intake before
discharge and adverse outcomes following tonsillectomy in pediatric patients.
These data contribute to evidence-based, safe, and cost-effective decision
making regarding discharge.Objective: To determine whether the quantity
o...περισσότερα »
Hearing preservation technique in cochlear implant
Outcomes review of modern via Auris Nasus Larynx
Publication date: Available online 11 March 2016*Source:*Auris Nasus Larynx
Author(s): Sally Nguyen, François Cloutier, Daniel Philippon, Mathieu Côté,
Richard Bussières, Douglas D. BackousIntroductionPreservation of residual
hearing in cochlear implantation is a main concern for patients and otologists.
New electrode arrays as well as development of minimally invasive technique have
allowed the expansion of indication criteria for cochlear implantation. The loss
of residual low-frequency hearing is thought to be the result of many
fa...περισσότερα »
High-speed digital imaging : Vocal-fold vibration of patients with Reinke's edema
observed using high-speed digital imagingvia Auris
Nasus LarynxPublication date: Available online 11 March 2016*Source:*Auris Nasus
LarynxAuthor(s): Takeshi Watanabe, Kenichi Kaneko, Koichi Sakaguchi, Haruo
TakahashiObjectiveWe aimed to assess the vocal-fold vibration of patients with
moderate-to-severe Reinke's edema using high-speed digital imaging (HSDI) and
videostroboscopy and to confirm HSDI usefulness in examining the vocal folds
with Reinke's edema.MethodsWe examined the vocal folds of seven patients (six
severe and one moderate; six females and one male; aged 55–74 year...περισσότερα »
Predictors of overall survival in human papillomavirus-associated oropharyngeal cancer
using the National Cancer Data Basevia
ScienceDirect Publication: Oral OncologyPublication date: May 2016*Source:*Oral
Oncology, Volume 56Author(s): Arya Amini, Jagar Jasem, Bernard L. Jones, Tyler
P. Robin, Jessica D. McDermott, Shilpa Bhatia, David Raben, Antonio Jimeno,
Daniel W. Bowles, Sana D. KaramObjectivesThis study identifies clinical
characteristics associated with HPV-positive oropharynx squamous cell carcinoma
(OPSCC) and evaluates predictors of overall survival (OS) in HPV-positive
patients undergoing definitive treatment within the National Cancer Data Base
(NCDB).Ma...περισσότερα »
Biosensors, Vol. 6, Pages 8: Aryl Diazonium Chemistry for the Surface Functionalization of Glassy Biosensors
Nanostring resonator and fiber-optics-based
biosensors are of interest as they offer high sensitivity, real-time
measurements and the ability to integrate with electronics. However, these
devices are somewhat impaired by issues related to surface modification. Both
nanostring resonators and photonic sensors employ glassy materials, which are
incompatible with electrochemistry. A surface chemistry approach providing
strong and… Continue reading Biosensors, Vol. 6, Pages 8: Aryl Diazonium
Chemistry for the Surface Functionalization of Glassy Biosensors
Kronisk utmattelsessyndrom og erfaring med «Lightning Process»
Årsaken til ME er uavklart og omstridt, og
behandlingsmulighetene er begrensede, men mange som har deltatt på kurset
Lightning Process har rapportert om positiv effekt. from
#ORL-AlexandrosSfakianakis via simeraentaxei on Inoreader http://ift.tt/1pp8ulw
via IFTTT
Cancers, Vol. 8, Pages 35: Mechanisms of Nuclear Export in Cancer and Resistance to Chemotherapy
Tumour suppressor proteins, such as p53,
BRCA1, and ABC, play key roles in preventing the development of a malignant
phenotype, but those that function as transcriptional regulators need to enter
the nucleus in order to function. The export of proteins between the nucleus and
cytoplasm is complex. It occurs through nuclear pores and exported proteins…
Continue reading Cancers, Vol. 8, Pages 35: Mechanisms of Nuclear Export in
Cancer and Resistance to Chemotherapy
Recurrent KRAS G12V pathogenic mutation in adenomatoid odontogenic tumours
*Recurrent KRAS G12V pathogenic mutation in
adenomatoid odontogenic tumours**via ScienceDirect Publication: Oral Oncology*
*Publication date: Available online 12 March 2016Source:Oral OncologyAuthor(s):
Carolina Cavalieri Gomes, Sílvia Ferreira de Sousa, Grazielle Helena Ferreira de
Menezes, Alessandra Pires Duarte, Thaís dos Santos Fontes Pereira, Rennan Garcia
Moreira, Wagner Henriques de Castro, Rolando A.R. Villacis, Silvia Regina
Rogatto, Marina Gonçalves Diniz, Ricardo Santiago Gomez**[HTML] από nih.gov*
*Recurrent *GNAS *mutations *define an unexpected pathway for
pancreati...περισσότερα »
Epidemiology of Low-Risk Human Papillomavirus
Epidemiology of Low-Risk Human Papillomavirus:
AbstractInfection with low-risk human papillomaviruses (HPVs), mostly type 6 and
11, in the upper respiratory tract causes recurrent respiratory papillomatosis
(RRP). Despite a relatively low incidence rate, RRP imposes significant
morbidity upon affected patients and an enormous financial burden on the
healthcare system. RRP can be further categorized into juvenile-onset RRP and
adult-onset RRP, depending on the onset age. They may associate with different
risk factors and incidence rates. Here, we review the epidemiology of RRP
cause...περισσότερα »
Acute trauma factor associations with suicidality across the first 5 years after traumatic brain injury
AlexAndros SfakianakisστοMedicine by
Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel
:00302841026Πριν από 33 δευτερόλεπτα
Publication date: Available online 14 March 2016
*Source:*Archives of Physical Medicine and RehabilitationAuthor(s): Matthew R.
Kesinger, Shannon B. Juengst, Hillary Bertisch, Janet P. Niemeier, Jason W.
Krellman, Mary Jo Pugh, Raj G. Kumar, Jason L. Sperry, Patricia M. Arenth, Jesse
R. Fann, Amy K. WagnerObjectiveTo determine whether severities of head and
extra-cranial injuries (ECI) were associated with suicidal ideation (SI) or
suicide attempt (SA) after traumatic brain injury (TBI).DesignFactors associated
with SI and SA were assessed in this inception cohort study using data
...περισσότερα »
A hepatitis C virus envelope polymorphism confers resistance to neutralization by polyclonal sera and broadly neutralizing monoclonal antibodies
AlexAndros SfakianakisστοMedicine by
Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel
:00302841026Πριν από 33 δευτερόλεπτα
Journal of Virologyfrom Gastroenterology via
xlomafota13 on Inoreader http://ift.tt/1pGbASevia IFTTT
Efficacy of direct-acting antiviral combination for patients with HCV genotype 1 infection and severe renal impairment or end-stage renal disease
AlexAndros SfakianakisστοMedicine by
Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel
:00302841026Πριν από 33 δευτερόλεπτα
Gastroenterologyfrom Gastroenterology via
xlomafota13 on Inoreader http://ift.tt/22f0nWKvia IFTTT
Elevated serum gamma-glutamyltransferase predicts advanced histological liver damage in chronic hepatitis b
AlexAndros SfakianakisστοMedicine by
Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel
:00302841026Πριν από 33 δευτερόλεπτα
Discovery Medicinefrom Gastroenterology via
xlomafota13 on Inoreader http://ift.tt/1pGbAS8via IFTTT
Colectomy rates in patients with ulcerative colitis following treatment with infliximab or ciclosporin: a systematic literature review
AlexAndros SfakianakisστοMedicine by
Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel
:00302841026Πριν από 33 δευτερόλεπτα
European Journal of Gastroenterology &
Hepatologyfrom Gastroenterology via xlomafota13 on Inoreader
http://ift.tt/22f0nWwvia IFTTT
Multidrug resistance protein 4 is a critical protein associated with the antiviral efficacy of nucleos(t)ide analogues
AlexAndros SfakianakisστοMedicine by
Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel
:00302841026Πριν από 33 δευτερόλεπτα
Liver Internationalfrom Gastroenterology via
xlomafota13 on Inoreader http://ift.tt/1pGbARXvia IFTTT
Shedding of hepatitis C virus in semen of HIV-infected men
AlexAndros SfakianakisστοMedicine by
Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel
:00302841026Πριν από 33 δευτερόλεπτα
Open Forum Infectious Diseasesfrom Gastroenterology
via xlomafota13 on Inoreader http://ift.tt/22f0lOqvia IFTTT
Utility of a molecular pre-screening program in advanced colorectal cancer for enrollment on biomarker-selected clinical trials
AlexAndros SfakianakisστοMedicine by
Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel
:00302841026Πριν από 33 δευτερόλεπτα
Annals of Oncologyfrom Gastroenterology via
xlomafota13 on Inoreader http://ift.tt/1pGbABzvia IFTTT
Prevalence, characteristics, and survival of children with esophageal atresia: A 32-year population-based study including 1,417,724 consecutive newborns
AlexAndros SfakianakisστοMedicine by
Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel
:00302841026Πριν από 33 δευτερόλεπτα
Birth Defects Research Part A: Clinical and
Molecular Teratologyfrom Gastroenterology via xlomafota13 on Inoreader
http://ift.tt/22f0ktTvia IFTTT
Patient-reported outcomes in Asian patients with chronic hepatitis c treated with ledipasvir and sofosbuvir
AlexAndros SfakianakisστοMedicine by
Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel
:00302841026Πριν από 33 δευτερόλεπτα
Medicinefrom Gastroenterology via xlomafota13 on
Inoreader http://ift.tt/1pGbABvvia IFTTT
Therapy with proton-pump inhibitors for gastroesophageal reflux disease does not reduce the risk for severe exacerbations in COPD
AlexAndros SfakianakisστοMedicine by
Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel
:00302841026Πριν από 33 δευτερόλεπτα
Respirologyfrom Gastroenterology via xlomafota13 on
Inoreader http://ift.tt/22f0kdpvia IFTTT
The recommended treatment algorithms of the BCLC and HKLC staging systems: does following these always improve survival rates for HCC patients?
AlexAndros SfakianakisστοMedicine by
Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel
:00302841026Πριν από 33 δευτερόλεπτα
Liver Internationalfrom Gastroenterology via
xlomafota13 on Inoreader http://ift.tt/1pGbxFVvia IFTTT
Confocal laser endomicroscopy in ulcerative colitis: a longitudinal study of endomicroscopic changes and response to medical therapy
AlexAndros SfakianakisστοMedicine by
Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel
:00302841026Πριν από 33 δευτερόλεπτα
Gastrointestinal Endoscopyfrom Gastroenterology via
xlomafota13 on Inoreader http://ift.tt/22f0l14via IFTTT
Faecal chitinase 3-like 1 is a reliable marker as accurate as faecal calprotectin in detecting endoscopic activity in adult patients with inflammatory bowel diseases
AlexAndros SfakianakisστοMedicine by
Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel
:00302841026Πριν από 33 δευτερόλεπτα
Alimentary Pharmacology and Therapeuticsfrom
Gastroenterology via xlomafota13 on Inoreader http://ift.tt/1pGbzh3via IFTTT
Mesalazine modified-release tablet in the treatment of ulcerative colitis in the active phase: a chinese, multicenter, single-blind, randomized controlled study
AlexAndros SfakianakisστοMedicine by
Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel
:00302841026Πριν από 33 δευτερόλεπτα
Advances in Therapyfrom Gastroenterology via
xlomafota13 on Inoreader http://ift.tt/22f0l0Ovia IFTTT
Diabetic biomarkers and the risk of proximal or distal gastric cancer
AlexAndros SfakianakisστοMedicine by
Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel
:00302841026Πριν από 33 δευτερόλεπτα
Journal of Gastroenterology and Hepatologyfrom
Gastroenterology via xlomafota13 on Inoreader http://ift.tt/1pGbxpwvia IFTTT
Coeliac disease in adolescence: Coping strategies and personality factors affecting compliance with gluten-free diet
AlexAndros SfakianakisστοMedicine by
Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel
:00302841026Πριν από 33 δευτερόλεπτα
Appetitefrom Gastroenterology via xlomafota13 on
Inoreader http://ift.tt/22f0hOMvia IFTTT
Should surveillance for liver cancer be modified in hepatitis C patients after treatment-related cirrhosis regression?
AlexAndros SfakianakisστοMedicine by
Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel
:00302841026Πριν από 33 δευτερόλεπτα
Liver Internationalfrom Gastroenterology via
xlomafota13 on Inoreader http://ift.tt/1pGbz0Avia IFTTT
Defining the Surgical Limits of Adenoidectomy so as to Prevent Recurrence of Adenoids
Defining the Surgical Limits of Adenoidectomy so as
to Prevent Recurrence of Adenoids: AbstractThis study aims to define the
surgical boundaries of adenoidectomy by demonstrating that recurrence of
adenoids and its symptoms can be avoided if a complete adenoidectomy is
performed, by following these surgical limits. A prospective descriptive study
was carried out at Speciality ENT Hospital, Mumbai, India. Endoscopic
adenoidectomy was performed in 83 patients using coblation technology. In all
patients, adenoids were removed superiorly till the periosteum over the body of
sphenoid; ...περισσότερα »
Voluminous Myoepithelioma of the Minor Salivary Glands Involving the Base of the Tongue
Voluminous Myoepithelioma of the Minor Salivary
Glands Involving the Base of the Tongue: Myoepithelioma is an extremely rare
tumour subtype and diagnosis is based on a wide variation of cellular
morphology. FNAC specimens do not always suffice for a definitive differential
diagnosis which depends on histology and immunohistochemistry of the lesion.
Case Presentation. A 54-year-old female came to our attention with dysphagia and
dyslalia of 6-month standing. Ear, Nose, and Throat (ENT) examination revealed a
voluminous mass on the right portion of the base of her tongue, where
postco...περισσότερα »
Effect of Preoperative Nerve Block on Postthyroidectomy Headache and Cervical Pain: A Randomized Prospective Study
Effect of Preoperative Nerve Block on
Postthyroidectomy Headache and Cervical Pain: A Randomized Prospective Study:
The aim of the current study was to investigate the efficacy of greater
occipital nerve (GON) block and bilateral superficial cervical plexuses (BSCP)
blocks in alleviating postoperative occipital headache and posterior neck pain
after thyroidectomy. This randomized prospective study consisted of 75 women
undergoing total thyroidectomy. Patients were randomized into three groups:
Group I (): patients receiving GON, Group II (): patients receiving bilateral
(BSCP) block...περισσότερα »
Significance of Interleukin-6 in Papillary Thyroid Carcinoma
Significance of Interleukin-6 in Papillary Thyroid
Carcinoma: This study sought to reveal the significance of IL-6 in papillary
thyroid carcinoma by determining its circulating levels, tumoral protein, and
mRNA expressions. As compared to the healthy individuals, serum IL-6 was
significantly higher in patients with benign thyroid diseases and PTC. Further,
its level was significantly higher in PTC patients as compared to patients with
benign thyroid diseases. ROC curves also confirmed a good discriminatory
efficacy of serum IL-6 between healthy individuals and patients with benign
th...περισσότερα »
Chronic Periodontitis and Erectile Dysfunction
Relationship between Chronic Periodontitis and
Erectile Dysfunction: A Narrative Review: Objective. To conduct a descriptive
literature review on research studies investigating the association between
chronic periodontitis (CP) and erectile dysfunction (ED). Methods. Cohort
studies, case-control studies, cross-sectional studies, randomized control
trials, and animal studies up to July 2015 that studied the relationship between
CP and ED were reviewed and reported. Data sources included PubMed, EMBASE,
Cochrane Library, and Clinicaltrials.gov. The themes “periodontal disease” and
“er...περισσότερα »
AOSpine Masters Series, Volume 4: Adult Spinal Deformities, Luiz Roberto Vialle, Lawrence G. Lenke, Kenneth M.C. Cheung. Thieme, New York, NY (2015)
alsfakianakisστοOtolaryngology
lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece
Crete,Anapafseos 5 Agios Nikolaos 72100,tel :
00302841026182,00306932607174Πριν από 47 δευτερόλεπτα
Publication date: May 2016 Source:World
Neurosurgery, Volume 89 Author(s): Daniel M. Sciubba from
#ORL-AlexandrosSfakianakis via ola Kala on Inoreader http://ift.tt/24ZzDvt via
IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete
72100,Greece,tel :00302841026182 & 00306932607174
Kronisk utmattelsessyndrom og erfaring med «Lightning Process»
alsfakianakisστοOtolaryngology
lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece
Crete,Anapafseos 5 Agios Nikolaos 72100,tel :
00302841026182,00306932607174Πριν από 47 δευτερόλεπτα
Årsaken til ME er uavklart og omstridt, og
behandlingsmulighetene er begrensede, men mange som har deltatt på kurset
Lightning Process har rapportert om positiv effekt. from
#ORL-AlexandrosSfakianakis via simeraentaxei on Inoreader http://ift.tt/1pp8ulw
via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete
72100,Greece,tel :00302841026182 & 00306932607174
Cancers, Vol. 8, Pages 35: Mechanisms of Nuclear Export in Cancer and Resistance to Chemotherapy
alsfakianakisστοOtolaryngology
lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece
Crete,Anapafseos 5 Agios Nikolaos 72100,tel :
00302841026182,00306932607174Πριν από 47 δευτερόλεπτα
Tumour suppressor proteins, such as p53,
BRCA1, and ABC, play key roles in preventing the development of a malignant
phenotype, but those that function as transcriptional regulators need to enter
the nucleus in order to function. The export of proteins between the nucleus and
cytoplasm is complex. It occurs through nuclear pores and exported proteins
[…]
Cancers, Vol. 8, Pages 35: Mechanisms of Nuclear Export in Cancer and Resistance to Chemotherapy
alsfakianakisστοOtolaryngology
lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece
Crete,Anapafseos 5 Agios Nikolaos 72100,tel :
00302841026182,00306932607174Πριν από 47 δευτερόλεπτα
Tumour suppressor proteins, such as p53,
BRCA1, and ABC, play key roles in preventing the development of a malignant
phenotype, but those that function as transcriptional regulators need to enter
the nucleus in order to function. The export of proteins between the nucleus and
cytoplasm is complex. It occurs through nuclear pores and exported proteins
[…]
Acute trauma factor associations with suicidality across the first 5 years after traumatic brain injury
alsfakianakisστοOtolaryngology
lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece
Crete,Anapafseos 5 Agios Nikolaos 72100,tel :
00302841026182,00306932607174Πριν από 47 δευτερόλεπτα
Publication date: Available online 14 March
2016 Source:Archives of Physical Medicine and Rehabilitation Author(s): Matthew
R. Kesinger, Shannon B. Juengst, Hillary Bertisch, Janet P. Niemeier, Jason W.
Krellman, Mary Jo Pugh, Raj G. Kumar, Jason L. Sperry, Patricia M. Arenth, Jesse
R. Fann, Amy K. Wagner ObjectiveTo determine whether severities of head and
extra-cranial injuries […]
Hospitals and GPs are offered incentives to reduce antibiotic prescribing
alsfakianakisστοOtolaryngology
lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece
Crete,Anapafseos 5 Agios Nikolaos 72100,tel :
00302841026182,00306932607174Πριν από 47 δευτερόλεπτα
GPs and hospitals in England will be given
incentives to reduce the number of antibiotics they prescribe, in an effort to
tackle the growing problem of antibiotic resistance.NHS England announced… from
#ORL-AlexandrosSfakianakis via simeraentaxei on Inoreader http://ift.tt/1QXlMfV
via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete
72100,Greece,tel :00302841026182 & 00306932607174
Rates of prophylactic mastectomy triple in decade, study shows
alsfakianakisστοOtolaryngology
lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece
Crete,Anapafseos 5 Agios Nikolaos 72100,tel :
00302841026182,00306932607174Πριν από 47 δευτερόλεπτα
The rates of prophylactic mastectomy more
than tripled from 2002 to 2012 in a US cohort of women with invasive breast
cancer despite this option offering no significant survival benefit over breast…
from #ORL-AlexandrosSfakianakis via simeraentaxei on Inoreader
http://ift.tt/1V5VoFJ via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos
5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 &
00306932607174
IJERPH, Vol. 13, Pages 313: Exploring Associations between Problematic Internet Use, Depressive Symptoms and Sleep Disturbance among Southern Chinese Adolescents
alsfakianakisστοOtolaryngology
lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece
Crete,Anapafseos 5 Agios Nikolaos 72100,tel :
00302841026182,00306932607174Πριν από 47 δευτερόλεπτα
The primary aim of this study was to examine
associations between problematic Internet use, depression and sleep disturbance,
and explore whether there were differential effects of problematic Internet use
and depression on sleep disturbance. A total of 1772 adolescents who
participated in the Shantou Adolescent Mental Health Survey were recruited in
2012 in Shantou, China. […]
Viruses, Vol. 8, Pages 79: Characterization of Intra-Type Variants of Oncogenic Human Papillomaviruses by Next-Generation Deep Sequencing of the E6/E7 Region
alsfakianakisστοOtolaryngology
lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece
Crete,Anapafseos 5 Agios Nikolaos 72100,tel :
00302841026182,00306932607174Πριν από 47 δευτερόλεπτα
Different human papillomavirus (HPV) types
are characterized by differences in tissue tropism and ability to promote cell
proliferation and transformation. In addition, clinical and experimental studies
have shown that some genetic variants/lineages of high-risk HPV (HR-HPV) types
are characterized by increased oncogenic activity and probability to induce
cancer. In this study, we designed and validated […]
BacterioFiles 243 – Fungal Friends Facilitate Phytoextraction (feat. Cat Adams)
alsfakianakisστοOtolaryngology
lifelong learning : Otolaryngology by Alexandros Sfakianakis,Greece
Crete,Anapafseos 5 Agios Nikolaos 72100,tel :
00302841026182,00306932607174Πριν από 47 δευτερόλεπτα
This episode: A conversation with Cat Adams
about how fungi help plants clean up toxic zinc nanoparticles in soil! (14.6 MB,
16 minutes) Show notes: from #ORL-AlexandrosSfakianakis via ola Kala on
Inoreader http://ift.tt/1SLX0Uu via IFTTT Medicine by Alexandros
G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182
& 00306932607174
Acute trauma factor associations with suicidality across the first 5 years after traumatic brain injury
Publication date: Available online 14 March 2016
*Source:*Archives of Physical Medicine and RehabilitationAuthor(s): Matthew R.
Kesinger, Shannon B. Juengst, Hillary Bertisch, Janet P. Niemeier, Jason W.
Krellman, Mary Jo Pugh, Raj G. Kumar, Jason L. Sperry, Patricia M. Arenth, Jesse
R. Fann, Amy K. WagnerObjectiveTo determine whether severities of head and
extra-cranial injuries (ECI) were associated with suicidal ideation (SI) or
suicide attempt (SA) after traumatic brain injury (TBI).DesignFactors associated
with SI and SA were assessed in this inception cohort study using data
...περισσότερα »
Pathologic Fracture in Osteosarcoma: Association with poorer overall survival
medicinesfakianakisστοMedicine by
Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel
:00302841026182 & 00306932607174Πριν από 1 ώρα
Publication date: Available online 14 March
2016 Source:European Journal of Surgical Oncology (EJSO) Author(s): Abhijeet
Ashok Salunke, Jaymin Shah, Nayan Gupta, Jyotindra Pandit from
#Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader
http://ift.tt/1RZgine via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos
5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 &
00306932607174
Cancers, Vol. 8, Pages 35: Mechanisms of Nuclear Export in Cancer and Resistance to Chemotherapy
medicinesfakianakisστοMedicine by
Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel
:00302841026182 & 00306932607174Πριν από 1 ώρα
Tumour suppressor proteins, such as p53,
BRCA1, and ABC, play key roles in preventing the development of a malignant
phenotype, but those that function as transcriptional regulators need to enter
the nucleus in order to function. The export of proteins between the nucleus and
cytoplasm is complex. It occurs through nuclear pores and exported proteins
[…]
Algorithms, Vol. 9, Pages 20: The Iterative Solution to Discrete-Time H∞ Control Problems for Periodic Systems
This paper addresses the problem of solving
discrete-time H ∞ control problems for periodic systems. The approach for
solving such a type of equations is well known in the literature. However, the
focus of our research is set on the numerical computation of the stabilizing
solution. In particular, two effective methods for practical realization of the
known iterative processes are described. Furthermore, a new iterative approach
is investigated and applied. On the basis of numerical experiments, we compare
the presented methods. A major conclusion is that the new iterative
approac...περισσότερα »
Atmosphere, Vol. 7, Pages 43: Reconstructing Fire Records from Ground-Based Routine Aerosol Monitoring
Long-term fire records are important to
understanding the trend of biomass burning and its interactions with air quality
and climate at regional and global scales. Traditionally, such data have been
compiled from ground surveys or satellite remote sensing. To obtain aerosol
information during a fire event to use in analyzing air quality, we propose a
new method of developing a long-term fire record for the contiguous United
States using an unconventional data source: ground-based aerosol monitoring.
Assisted by satellite fire detection, the mass concentration, size distribution,
an...περισσότερα »
Energies, Vol. 9, Pages 194: Predictive Control Applied to a Solar Desalination Plant Connected to a Greenhouse with Daily Variation of Irrigation Water Demand
The water deficit in the Mediterranean area is a
known matter severely affecting agriculture. One way to avoid the aquifers'
exploitation is to supply water to crops by using thermal desalination
processes. Moreover, in order to guarantee long-term sustainability, the
required thermal energy for the desalination process can be provided by solar
energy. This paper shows simulations for a case study in which a solar
multi-effect distillation plant produces water for irrigation purposes. Detailed
models of the involved systems are the base of a predictive controller to
operate the de...περισσότερα »
Animals, Vol. 6, Pages 21: Updating Animal Welfare Thinking: Moving beyond the “Five Freedoms” towards “A Life Worth Living”
The Five Freedoms have had major impact on animal
welfare thinking internationally. However, despite clear initial statements that
the words 'freedom from' should indicate 'as free as possible from', the
Freedoms have come to be represented as absolute or fundamental freedoms, even
rights, by some animal advocate and other groups. Moreover, a marked increase in
scientific understanding over the last two decades shows that the Freedoms do
not capture the more nuanced knowledge of the biological processes that is
germane to understanding animal welfare and which is now available to
...περισσότερα »
Algorithms, Vol. 9, Pages 19: Review of Recent Advances in the Application of the Wavelet Transform to Diagnose Cracked Rotors
Wavelet transform (WT) has been used in the
diagnosis of cracked rotors since the 1990s. At present, WT is one of the most
commonly used tools to treat signals in several fields. Understandably, this has
been an area of extensive scientific research, which is why this paper aims to
summarize briefly the major advances in the field since 2008. The present review
considers advances in the use and application of WT, the selection of the
parameters used, and the key achievements in using WT for crack diagnosis.from
#Medicine via ola Kala on Inoreader http://ift.tt/1QQPXqZMedicine by
...περισσότερα »
Remote Sensing, Vol. 8, Pages 241: Monitoring Riverbank Erosion in Mountain Catchments Using Terrestrial Laser Scanning
Sediment yield is a key factor in river basins
management due to the various and adverse consequences that erosion and sediment
transport in rivers may have on the environment. Although various contributions
can be found in the literature about sediment yield modeling and bank erosion
monitoring, the link between weather conditions, river flow rate and bank
erosion remains scarcely known. Thus, a basin scale assessment of sediment yield
due to riverbank erosion is an objective hard to be reached. In order to enhance
the current knowledge in this field, a monitoring method based on...περισσότερα »
Shedding of hepatitis C virus in semen of HIV-infected men
Open Forum Infectious Diseasesfrom #Medicine via
ola Kala on Inoreader http://ift.tt/22f0lOqvia IFTTT
Utility of a molecular pre-screening program in advanced colorectal cancer for enrollment on biomarker-selected clinical trials
Annals of Oncologyfrom #Medicine via ola Kala on
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Prevalence, characteristics, and survival of children with esophageal atresia: A 32-year population-based study including 1,417,724 consecutive newborns
Birth Defects Research Part A: Clinical and
Molecular Teratologyfrom #Medicine via ola Kala on Inoreader
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Patient-reported outcomes in Asian patients with chronic hepatitis c treated with ledipasvir and sofosbuvir
Medicinefrom #Medicine via ola Kala on Inoreader
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Safety of Intra-arterial Catheter Directed Thrombolysis: Does Level of Care Matter?
Publication date: Available online 14 March 2016
*Source:*European Journal of Vascular and Endovascular SurgeryAuthor(s): L.
Koraen-Smith, M. Wängberg, C. Montán, P. Gillgren, C.-M. WahlgrenObjectivesThe
aim was to assess whether the level of care influenced the safety related
outcomes of catheter directed thrombolysis (CDT) for patients presenting with
limb ischaemia and dialysis access thrombosis.MethodsThis was a retrospective
cohort study. All consecutive patients at two tertiary referral centres for
vascular surgery undergoing CDT for limb ischaemia and dialysis access
thromb...περισσότερα »
20Q: Tinnitus and Hyperacusis - Beyond the Ear
As auditory neuroscientists, we are mainly
concerned with the way in which the different dimensions of sound (e.g.,
intensity, frequency and time) activate specific regions of the peripheral or
central auditory system. We become "auditory-centric" and ignore the fact that
most regions of the central auditory pathway receive inputs and send outputs to
many nonauditory centers involved with emotion, memory, body position, vision,
touch and likely many other regions. By integrating many different types of
information, we are able to carry out complex activities such as turning our
he...περισσότερα »
Enterococcus Growth on Eelgrass (Zostera marina); Implications for Water Quality
Enterococci are fecal indicator bacteria used to
monitor fecal pollution of recreational waters. When enterococci levels exceed
health standards, fecal pollution is assumed as the cause. Enterococci growing
on plants limit their usefulness as fecal indicator bacteria. Here we examined
enterococcal growth on eelgrass in Mission Bay, CA where enterococci levels have
exceeded water quality thresholds. 69 eelgrass samples were collected from six
sites, shaken to remove enterococci attached to plant surfaces and the eluant
filtered onto culture media. Isolates were then identified to s...περισσότερα »
Hospitals and GPs are offered incentives to reduce antibiotic prescribing
GPs and hospitals in England will be given
incentives to reduce the number of antibiotics they prescribe, in an effort to
tackle the growing problem of antibiotic resistance.NHS England announced… from
#ORL-AlexandrosSfakianakis via simeraentaxei on Inoreader http://ift.tt/1QXlMfV
via IFTTT
Rates of prophylactic mastectomy triple in decade, study shows
The rates of prophylactic mastectomy more
than tripled from 2002 to 2012 in a US cohort of women with invasive breast
cancer despite this option offering no significant survival benefit over breast…
from #ORL-AlexandrosSfakianakis via simeraentaxei on Inoreader
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IJERPH, Vol. 13, Pages 313: Exploring Associations between Problematic Internet Use, Depressive Symptoms and Sleep Disturbance among Southern Chinese Adolescents
The primary aim of this study was to examine
associations between problematic Internet use, depression and sleep disturbance,
and explore whether there were differential effects of problematic Internet use
and depression on sleep disturbance. A total of 1772 adolescents who
participated in the Shantou Adolescent Mental Health Survey were recruited in
2012 in Shantou, China.… Continue reading IJERPH, Vol. 13, Pages 313: Exploring
Associations between Problematic Internet Use, Depressive Symptoms and Sleep
Disturbance among Southern Chinese Adolescents
Viruses, Vol. 8, Pages 79: Characterization of Intra-Type Variants of Oncogenic Human Papillomaviruses by Next-Generation Deep Sequencing of the E6/E7 Region
Different human papillomavirus (HPV) types
are characterized by differences in tissue tropism and ability to promote cell
proliferation and transformation. In addition, clinical and experimental studies
have shown that some genetic variants/lineages of high-risk HPV (HR-HPV) types
are characterized by increased oncogenic activity and probability to induce
cancer. In this study, we designed and validated… Continue reading Viruses, Vol.
8, Pages 79: Characterization of Intra-Type Variants of Oncogenic Human
Papillomaviruses by Next-Generation Deep Sequencing of the E6/E7 Region
The complexity of daily life walking in older adult community-dwelling fallers and non-fallers
Publication date: Available online 13 March
2016 Source:Journal of Biomechanics Author(s): Espen A.F. Ihlen, Aner Weiss,
Alan Bourke, Jorunn L. Helbostad, Jeffrey M. Hausdorff Complexity of human
physiology and physical behavior has been suggested to decrease with aging and
disease and make older adults more susceptible to falls. The present study
investigates complexity in daily… Continue reading The complexity of daily life
walking in older adult community-dwelling fallers and non-fallers
Hitachi signs biopsy deal with MedCom
Hitachi Medical Systems Europe has signed an
agreement with MedCom to distribute… Read more on AuntMinnieEurope.com Related
Reading: Hitachi Aloka debuts Arietta V70 with enhanced elastography functions
Hitachi unveils new ultrasound system Fujifilm, Hitachi sign distribution deal
Hitachi launches new version of Oasis at ECR Xograph forms alliance with Hitachi
from #ORL-AlexandrosSfakianakis via simeraentaxei on… Continue reading Hitachi
signs biopsy deal with MedCom
U.K. research could advance MRI lung scans
British researchers have developed a process
using specially treated krypton… Read more on AuntMinnieEurope.com Related
Reading: MRI lung perfusion looks set for broader clinical use from
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ESTI reschedules meeting for Krakow in October
After canceling its annual meeting in
Istanbul due to concerns over security,… Read more on AuntMinnieEurope.com
Related Reading: Security concerns lead to cancellation of ESTI 2016 ESTI
prepares for joint meeting in Spain ESTI: New 3D tool displays promise for rib
evaluations ESTI prepares for annual meeting in Amsterdam from
#ORL-AlexandrosSfakianakis via simeraentaxei on Inoreader… Continue reading ESTI
reschedules meeting for Krakow in October
Percutaneous cryoablation of hepatic tumors: Long-term experience of a large U.S. series
AlexAndros SfakianakisστοMedicine by
Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel
:00302841026Πριν από 1 ώρα
Abdominal Imagingfrom Gastroenterology via
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Role of major resection in pulmonary metastasectomy for colorectal cancer in the Spanish Prospective Multicenter Study (GECMP-CCR)
AlexAndros SfakianakisστοMedicine by
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Annals of Oncologyfrom Gastroenterology via
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Association of financial strain with symptom burden and quality of life for patients with lung or colorectal cancer
AlexAndros SfakianakisστοMedicine by
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Journal of Clinical Oncologyfrom Gastroenterology
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The genetics of drug efficacy: opportunities and challenges
AlexAndros SfakianakisστοMedicine by
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Nature Reviews Genetics. doi:10.1038/nrg.2016.12
Authors: Matthew R. Nelson, Toby Johnson, Liling Warren, Arlene R. Hughes,
Stephanie L. Chissoe, Chun-Fang Xu & Dawn M. Waterworthfrom Genetics via
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