Αρχειοθήκη ιστολογίου

Αλέξανδρος Γ. Σφακιανάκης
ΩτοΡινοΛαρυγγολόγος
Αναπαύσεως 5
Άγιος Νικόλαος Κρήτη 72100
2841026182
6032607174

Παρασκευή 8 Απριλίου 2016

OtoRhinoLaryngology & Medicine,New Articles,April 8th,2016,a


The Evaluation of Liver Function and Surgical Influence by ICGR15 after Chemotherapy for Colorectal Liver Metastases.

Alexandros G. SfakianakisστοMelanoma by Alexandros G. SfakianakisΠριν από 6 δευτερόλεπτα
*The Evaluation of Liver Function and Surgical Influence by ICGR15 after Chemotherapy for Colorectal Liver Metastases.* J Cancer. 2016;7(5):595-9 Authors: Hiwatashi K, Ueno S, Sakoda M, Iino S, Minami K, Mori S, Kita Y, Baba K, Kurahara H, Mataki Y, Maemura K, Shinchi H, Natsugoe S Abstract Background; Approximately 60% of patients with colorectal cancer develop liver metastasis at some point after diagnosis. The aim of this study is to investigate whether the evaluation of ICGR15 preoperatively is a useful clinical indicator of hepatic injury following chemotherapy and to invest... περισσότερα »

On the third largest eigenvalue of graphs

orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 6 δευτερόλεπτα
Publication date: 15 August 2016 Source:Linear Algebra and its Applications, Volume 503 Author(s): Mohammad Reza Oboudi Let G be a graph with eigenvalues λ1(G)≥⋯≥λn(G). In this paper we investigate the value of λ3(G). We show that if the multiplicity of −1 as an eigenvalue of G is at most n−13, then λ3(G)≥0. We prove that… Continue reading On the third largest eigenvalue of graphs

Molecular epidemiology and in vitro antifungal susceptibility testing of 108 clinical Cryptococcus neoformans sensu lato and Cryptococcus gattii sensu lato isolates from Denmark

orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 6 δευτερόλεπτα
Summary Cryptococcosis is mainly caused by members of the Cryptococcus gattii/Cryptococcus neoformans species complexes. Here, we report the molecular characterisation and in vitro antifungal susceptibility of Danish clinical cryptococcal isolates. Species, genotype, serotype and mating type were determined by amplified fragment length polymorphism (AFLP) fingerprinting and qPCR. EUCAST E.Def 7.2 MICs were determined for amphotericin… Continue reading Molecular epidemiology and in vitro antifungal susceptibility testing of 108 clinical Cryptococcus neoformans sensu lato and Cryptoco... περισσότερα »

A cluster of Geotrichum clavatum (Saprochaete clavata) infection in haematological patients: a first Italian report and review of literature

orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 6 δευτερόλεπτα
Summary Invasive fungal infections, usually Aspergillus and Candida, represent a major cause of morbidity and mortality in patients with malignant haematological diseases, but in the last years rare fungal infections have more frequently been reported. Here, we report the clinical history of three patients affected with haematological malignancies who developed an infection caused by Geotrichum… Continue reading A cluster of Geotrichum clavatum (Saprochaete clavata) infection in haematological patients: a first Italian report and review of literature

Performance of MALDI-TOF MS platforms for fungal identification

orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 6 δευτερόλεπτα
Summary Matrix-assisted laser desorption/ionisation mass spectrometry (MALDI-TOF MS) is increasingly used by clinical microbiology laboratories to cope with the need for rapid, cost-effective and accurate identification of microorganisms. Several research teams have recently succeed in identifying moulds using MALDI-TOF MS, which was first adapted to bacteria, then to yeast identification. Since 2004, different commercial firms… Continue reading Performance of MALDI-TOF MS platforms for fungal identification

Measuring IL-6 and sIL-6R in serum from patients treated with tocilizumab and/or siltuximab following CAR T cell therapy.

orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 6 δευτερόλεπτα
We report the comparative quantification of IL-6 and sIL-6R using Luminex-based immunoassay kits from two vendors. Our results indicate good agreement of the commercial immunoassays in measurement of IL-6 but disagreement in quantitation of sIL-6R.We found that both Siltuximab and Tocilizumab can interfere with the measurement of their respective ligands using reagents from one vendor… Continue reading Measuring IL-6 and sIL-6R in serum from patients treated with tocilizumab and/or siltuximab following CAR T cell therapy.

Morphometry, biogeography and ecology of Calcidiscus and Umbilicosphaera in the South Atlantic

orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 6 δευτερόλεπτα
Publication date: Available online 7 April 2016 Source:Revue de Micropaléontologie Author(s): Karl-Heinz Baumann, Mariem Saavedra-Pellitero, Babette Böckel, Carola Ott Here we present morphometrical evaluation, biogeographical distribution patterns and ecological information for five coccolithophore taxa (Calcidiscus leptoporus, C. leptoporus small, C. quadriperforatus, Umbilicosphaera foliosa and U. sibogae). This information is based on data obtained from surface… Continue reading Morphometry, biogeography and ecology of Calcidiscus and Umbilicosphaera in the South Atlantic

Fanconi anemia proteins in telomere maintenance

orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 6 δευτερόλεπτα
Publication date: Available online 8 April 2016 Source:DNA Repair Author(s): Jaya Sarkar, Yie Liu Mammalian chromosome ends are protected by nucleoprotein structures called telomeres. Telomeres ensure genome stability by preventing chromosome termini from being recognized as DNA damage. Telomere length homeostasis is inevitable for telomere maintenance because critical shortening or over-lengthening of telomeres may lead… Continue reading Fanconi anemia proteins in telomere maintenance

A novel small molecule inhibitor of the DNA repair protein Ku70/80

orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 6 δευτερόλεπτα
Publication date: Available online 7 April 2016 Source:DNA Repair Author(s): Eric Weterings, Alfred C. Gallegos, Lauren N. Dominick, Laurence S. Cooke, Trace N. Bartels, Josef Vagner, Terry O. Matsunaga, Daruka Mahadevan Non-Homologous End-Joining (NHEJ) is the predominant pathway for the repair of DNA double strand breaks (DSBs) in human cells. The NHEJ pathway is frequently… Continue reading A novel small molecule inhibitor of the DNA repair protein Ku70/80

Interaction between APC and Fen1 during breast carcinogenesis

orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 6 δευτερόλεπτα
Publication date: Available online 7 April 2016 Source:DNA Repair Author(s): Satya Narayan, Aruna S. Jaiswal, Brian K. Law, Mohammad A. Kamal, Arun K. Sharma, Robert A. Hromas Aberrant DNA base excision repair (BER) contributes to malignant transformation. However, inter-individual variations in DNA repair capacity plays a key role in modifying breast cancer risk. We review… Continue reading Interaction between APC and Fen1 during breast carcinogenesis

Salivary agglutinin is the major component in human saliva that modulates the lectin pathway of the complement system.

orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 6 δευτερόλεπτα
Authors: Gunput ST, Wouters D, Nazmi K, Cukkemane N, Brouwer M, Veerman EC, Ligtenberg AJ Abstract Saliva interacts with blood after mucosal damage or leakage of gingival crevicular fluid. Surface-adsorbed salivary agglutinin (SAG) activates the lectin pathway (LP) of the complement system via mannose-binding lectin, while SAG in solution inhibits complement activation. In the present… Continue reading Salivary agglutinin is the major component in human saliva that modulates the lectin pathway of the complement system.

Microvascular Reconstruction of Free Jejunal Graft

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 6 δευτερόλεπτα
in Larynx-preserving Esophagectomy for Cervical Esophageal Carcinoma: Background: Losing the ability to speak severely affects the quality of life, and patients who have undergone laryngectomy tend to become depressed, which may lead to social withdrawal. Recently, with advancements in chemoradiotherapy and with alternative perspectives on postoperative quality of life, larynx preservation has been pursued; however, the selection of candidates and the optimal reconstructive procedure remain controversial. In this study, we retrospectively reviewed our experience with free jejunal g... περισσότερα »

Effect of Artificial Nerve Conduit Vascularization on Peripheral Nerve

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 6 δευτερόλεπτα
in a Necrotic Bed: [image: image] Background: Several types of artificial nerve conduit have been used for bridging peripheral nerve gaps as an alternative to autologous nerves. However, their efficacy in repairing nerve injuries accompanied by surrounding tissue damage remains unclear. We fabricated a novel nerve conduit vascularized by superficial inferior epigastric (SIE) vessels and evaluated whether it could promote axonal regeneration in a necrotic bed. Methods: A 15-mm nerve conduit was implanted beneath the SIE vessels in the groin of a rat to supply it with blood vessel... περισσότερα »

The Evaluation of Liver Function and Surgical Influence by ICGR15 after Chemotherapy for Colorectal Liver Metastases.

Alexandros G. SfakianakisστοThyroid Disorders by Alexandros G.SfakianakisΠριν από 6 δευτερόλεπτα
*The Evaluation of Liver Function and Surgical Influence by ICGR15 after Chemotherapy for Colorectal Liver Metastases.* J Cancer. 2016;7(5):595-9 Authors: Hiwatashi K, Ueno S, Sakoda M, Iino S, Minami K, Mori S, Kita Y, Baba K, Kurahara H, Mataki Y, Maemura K, Shinchi H, Natsugoe S Abstract Background; Approximately 60% of patients with colorectal cancer develop liver metastasis at some point after diagnosis. The aim of this study is to investigate whether the evaluation of ICGR15 preoperatively is a useful clinical indicator of hepatic injury following chemotherapy and to invest... περισσότερα »

The use of electrodessication in the treatment of cutaneous neurofibromatosis

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 7 δευτερόλεπτα
: a retrospective patient satisfaction outcome assessment via British Association of Plastic Surgeons Publication date: Available online 7 April 2016 *Source:*Journal of Plastic, Reconstructive & Aesthetic Surgery Author(s): C.G. Lutterodt, A. Mohan, N. Kirkpatrick IntroductionNF-1 is an autosomal dominant disease that can give rise to hundreds of cutaneous neurofibromas. In addition to localised symptoms such as pain and pruritus these lesions can have a devastating psychosocial impact. To date there is no consensus on the optimal management of these lesions. We present clinical and pa... περισσότερα »

The free inverted omega-shaped flap for circumferential hypopharyngeal reconstruction with simultaneous neck skin defect

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 7 δευτερόλεπτα
The free inverted omega-shaped flap for circumferential hypopharyngeal reconstruction with simultaneous neck skin defect: Background Circumferential hypopharyngeal defect with simultaneous skin defect can pose complicated reconstructive challenge for reconstructive microsurgeons. Our experience with the versatile inverted-omega flap tubing design is proposed to accommodate such problem. Methods From 2012 to 2015, 13 anterolateral thigh (ALT) flaps and one anteromedial thigh (AMT) flap were harvested for reconstruction of circumferential hypopharyngeal defects with skin defects in 14...περισσότερα »

Leprous Neuropathy

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 7 δευτερόλεπτα
Prevalence of Leprous Neuropathy determined by Neurosensory Testing in an Endemic Zone in Ecuador: Development of an Algorithm to Identify Who might benefit from Early Neurolysis via British Association of Plastic Surgeons Publication date: Available online 7 April 2016 *Source:*Journal of Plastic, Reconstructive & Aesthetic Surgery Author(s): Pablo A. Baltodano, Danielle H. Rochlin, Jonathan Noboa, Karim A. Sarhane, Gedge D. Rosson, A.Lee Dellon The potential for successful microneurosurgical intervention in leprous neuropathy (LN) depends upon diagnosis of chronic compression before ... περισσότερα »

The role of airway hyperresponsiveness measured by methacholine challenge test in defining asthma severity in asthma-obesity syndrome.

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 7 δευτερόλεπτα
The role of airway hyperresponsiveness measured by methacholine challenge test in defining asthma severity in asthma-obesity syndrome.: Purpose of review: Asthma is a complex disease defined by chronic inflammation of the airways. In research and clinical practice measures used for diagnosis, an assessment of control and severity of asthma are varied and there exists no gold standard. To date, several studies have explored the link between obesity and asthma although the exact mechanism is not yet fully understood. A study undertaken by our research group in 2015, on the effects of ...περισσότερα »

Food allergy management in schools.

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 7 δευτερόλεπτα
Doctor, my child is bullied: food allergy management in schools.: Purpose of review: Studies suggest that food allergies have increased in prevalence, resulting in most school classrooms having more than one child affected. Children with food allergies are vulnerable for experiencing potentially life-threatening allergic reactions, as well as social consequences such as bullying. Management recommendations for food allergies in schools should incorporate knowledge of both issues. Recent findings: Current recommendations for food allergy management in schools focus on appropriate avo... περισσότερα »

Parasite antigens and allergens in neonates

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 9 δευτερόλεπτα
Cellular gene expression induced by parasite antigens and allergens in neonates from parasite-infected mothers via ScienceDirect Publication: Molecular Immunology Publication date: May 2016 *Source:*Molecular Immunology, Volume 73 Author(s): Peter T. Soboslay, Thorsten Orlikowsky, Xiangsheng Huang, Christian Gille, Bärbel Spring, Lars Kocherscheidt, Abram Agossou, Meba Banla, Michael Bonin, Carsten Köhler Prenatal exposure to parasite antigens or allergens will influence the profile and strength of postnatal immune responses, such contact may tolerize and increase susceptibility to fut... περισσότερα »

Breastfeeding and perinatal exposure, and the risk of asthma and allergies.

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 9 δευτερόλεπτα
Breastfeeding and perinatal exposure, and the risk of asthma and allergies.: Purpose of review: Exposures during the perinatal period, a phase of rapid development, may have a profound and sustained effect on disease risk. In particular, perinatal exposures may influence the development and maturation of the infant immune system and the risk of allergic disease. We aimed to summarize the current literature on perinatal exposures and the risk of asthma and allergic disease Recent findings: Increased risk of offspring wheeze or asthma was found for: maternal obesity and hypertension d...περισσότερα »

Transient depletion of the bacterial flora enhanced the development of oral tolerance

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 10 δευτερόλεπτα
The GARP/Latent TGF-β1 complex on Treg cells modulates the induction of peripherally derived Treg cells during oral tolerance: Treg cells can secrete latent TGF-β1 (LTGF-β1), but can also utilize an alternative pathway for transport and expression of LTGF-β1 on the cell surface in which LTGF-β1 is coupled to a distinct LTGF-β binding protein termed GARP/LRRC32. The function of the GARP/LTGF-β1 complex has remained elusive. Here, we examine in vivo the roles of GARP and TGF-β1 in the induction of oral tolerance. When Foxp3− OT-II T cells were transferred to wild-type recipient mice ... περισσότερα »

Ontogeny of Human IgE-expressing B Cells and Plasma Cells

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 10 δευτερόλεπτα
Ontogeny of Human IgE-expressing B Cells and Plasma Cells: [image: cover.gif?v=1&s=eca9898eab49b7d92da2055c] Abstract Background IgE-expressing (IgE+) plasma cells (PCs) provide a continuous source of allergen specific IgE that is central to allergic responses. The extreme sparsity of IgE+ cells *in vivo* has confined their study almost entirely to mouse models. Objective To characterise the development pathway of human IgE+ PCs and to determine the ontogeny of human IgE+ PCs. Methods To generate human IgE+ cells we cultured tonsil B cells with IL-4 and anti-CD40. Using FACS and ...περισσότερα »

Regulatory niche in intestinal stem cells

Alexandros G. SfakianakisστοPhysiology by Alexandros G.SfakianakisΠριν από 11 δευτερόλεπτα
Abstract The niche constitutes a unique category of cells which support the microenvironment for the maintenance and self-renewal of stem cells. Intestinal stem cells reside at the base of the crypt, which contains adjacent epithelial cells, stromal cells, smooth muscle cells, soluble and cell-associated growth and differentiation factors. We summarize here recent advancements in our understanding of the crucial role of the niche in regulating stem cells. The stem cell niche maintains a balance among quiescence, proliferation, and regeneration of intestinal stem cells after injury.... περισσότερα »

Attenuated flow-induced dilation of middle cerebral arteries is related to increased vascular oxidative stress in rats on a short-term high salt diet

Alexandros G. SfakianakisστοPhysiology by Alexandros G.SfakianakisΠριν από 11 δευτερόλεπτα
Abstract *Aim*: To determine flow-induced dilation (FID) and the role of oxidative stress/antioxidative capacity in isolated, pressurized middle cerebral arteries (MCA) of high salt (HS) fed rats. *Methods*: 11-weeks old healthy male Sprague-Dawley rats were fed 0.4%NaCl (low salt (LS) group) or 4%NaCl (HS group) diet for 1 week. Reactivity of MCA in response to stepwise increase in pressure gradient (Δ10-Δ100 mmHg) was determined in the absence or presence of superoxide dismutase (SOD) mimetic TEMPOL and/or nitric oxide synthases (NOS) inhibitor Nω-nitro-L-arginine methyl ester (L-...περισσότερα »

Relationship between motor corticospinal excitability and ventilatory response during intense exercise

Alexandros G. SfakianakisστοPhysiology by Alexandros G.SfakianakisΠριν από 11 δευτερόλεπτα
AbstractPurpose Effort sense has been suggested to be involved in the hyperventilatory response during intense exercise (IE). However, the mechanism by which effort sense induces an increase in ventilation during IE has not been fully elucidated. The aim of this study was to determine the relationship between effort-mediated ventilatory response and corticospinal excitability of lower limb muscle during IE. Methods Eight subjects performed 3 min of cycling exercise at 75–85 % of maximum workload twice (IE1st and IE2nd). IE2nd was performed after 60 min of resting recovery following...περισσότερα »

Lessons from altitude: Cerebral perfusion insights and their potential clinical significance

Alexandros G. SfakianakisστοPhysiology by Alexandros G.SfakianakisΠριν από 11 δευτερόλεπτα
Rapid ascent to high altitude commonly results in acute mountain sickness, and on occasion potentially fatal high-altitude cerebral edema. The exact pathophysiological mechanisms behind these syndromes remain to be determined. One of the main theories to explain the development of Acute Mountain Sickness (AMS) is an increase in intracranial pressure (ICP). Vasogenic (extracellular water accumulation due to increased permeability of the blood– brain barrier) and cytotoxic (intracellular) oedema have also been postulated as the mechanisms that underlie High Altitude Cerebral Edema (...περισσότερα »

The Childhood Atopic Dermatitis Impact Scale

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 11 δευτερόλεπτα
Development of a Japanese Culturally Modified Version of the Childhood Atopic Dermatitis Impact Scale (JCMV-CADIS) via Allergology International Publication date: Available online 8 April 2016 *Source:*Allergology International Author(s): Chikae Yamaguchi, Masaki Futamura, Sarah L. Chamlin, Yukihiro Ohya, Midori Asano BackgroundThe Childhood Atopic Dermatitis Impact Scale (CADIS) was developed to measure the impact of AD on QoL in both affected children and their families. However, no scale of this kind exists in Japan. The aims of this study were to validate the Japanese Culturally Mo...περισσότερα »

Skin Biomes

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 11 δευτερόλεπτα
Skin Biomes: AbstractThe cutaneous microbiome has been investigated broadly in recent years and some traditional perspectives are beginning to change. A diverse microbiome exists on human skin and has a potential to influence pathogenic microbes and modulate the course of skin disorders, e.g. atopic dermatitis. In addition to the known dysfunctions in barrier function of the skin and immunologic disturbances, evidence is rising that frequent skin disorders, e.g. atopic dermatitis, might be connected to a dysbiosis of the microbial community and changes in the skin microbiome. As a ... περισσότερα »

Gene Therapy for the Treatment of Primary Immune Deficiencies

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 11 δευτερόλεπτα
Gene Therapy for the Treatment of Primary Immune Deficiencies: AbstractThe use of gene therapy in the treatment of primary immune deficiencies (PID) has advanced significantly in the last decade. Clinical trials for X-linked severe combined immunodeficiency, adenosine deaminase deficiency (ADA), chronic granulomatous disease, and Wiskott-Aldrich syndrome have demonstrated that gene transfer into hematopoietic stem cells and autologous transplant can result in clinical improvement and is curative for many patients. Unfortunately, early clinical trials were complicated by vector-rela...περισσότερα »

Preoperative serum lactate cannot predict in-hospital mortality after decompressive craniectomy in traumatic brain injury

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 11 δευτερόλεπτα
Preoperative serum lactate cannot predict in-hospital mortality after decompressive craniectomy in traumatic brain injury: Abstract PurposeDespite the utility of serum lactate for predicting clinical courses, little information is available on the topic after decompressive craniectomy. This study was conducted to determine the ability of perioperative serum lactate levels to predict in-hospital mortality in traumatic brain-injury patients who received emergency or urgent decompressive craniectomy. MethodsThe medical records of 586 consecutive patients who underwent emergency o... περισσότερα »

Venous carbon dioxide embolism

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 11 δευτερόλεπτα
Impact of nitrous oxide on the haemodynamic consequences of venous carbon dioxide embolism: An experimental study: [image: image] BACKGROUND: Nitrous oxide (N2O) is still considered an important component of general anaesthesia. However, should gas embolisation occur as result of carbon dioxide (CO2) pneumoperitoneum, N2O may compromise safety, as the consequences of a gas embolus consisting of a combination of CO2 and N2O may be more severe than CO2 alone. OBJECTIVE: This experimental study was designed to compare the cardiopulmonary consequences of gas embolisation with a N2O/CO2... περισσότερα »

Intraoperative anaphylaxis to neuromuscular blocking agents

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 13 δευτερόλεπτα
the incidence over 9 years at two tertiary hospitals in South Korea: A retrospective observational study: BACKGROUND: Intraoperative anaphylaxis to neuromuscular blocking agents (NMBAs) is a rare event that is unpredictable and potentially life threatening. Most of the previous reports on such intraoperative anaphylaxis used market share surveys or self-reported data to estimate the incidence. OBJECTIVE: To determine the incidences of intraoperative anaphylaxis to NMBAs using electronic medical records. DESIGN: A retrospective observational study. SETTING: Two tertiary hospitals... περισσότερα »

Ticagrelor-induced bleeding : Platelet supplementation

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 13 δευτερόλεπτα
The effectiveness of platelet supplementation for the reversal of ticagrelor-induced inhibition of platelet aggregation: An in-vitro study: BACKGROUND: Management of ticagrelor-induced bleeding is challenging, as no antidote is currently available. Platelet transfusion, usually proposed to reverse antiplatelet drugs, has been suggested to be ineffective but few data are available. OBJECTIVE: To assess the efficacy of platelet supplementation to restore platelet aggregation inhibited by ticagrelor. DESIGN: In vitro study. SETTING: Blood samples were obtained from the French Blood Ba... περισσότερα »

Education and training for nonanesthesia providers performing deep sedation.

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 13 δευτερόλεπτα
Education and training for nonanesthesia providers performing deep sedation.: Purpose of review: There has been a significant increase in the number and types of procedures performed outside of the operating room with nonanesthesia providers administering sedation. This review describes current recommendations for training nonanesthesiologists involved in administering deep sedation, summarizes best practices and highlights select patient outcomes. Recent findings: There are numerous guidelines and standards related to the administration of deep sedation. However, there are no unive...περισσότερα »

Use of computer-assisted drug therapy outside the operating room.

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 13 δευτερόλεπτα
Use of computer-assisted drug therapy outside the operating room.: Purpose of review: The number of procedures performed in the out-of-operating room setting under sedation has increased many fold in recent years. Sedation techniques aim to achieve rapid patient turnover through the use of short-acting drugs with minimal residual side-effects (mainly propofol and opioids). Even for common procedures, the practice of sedation delivery varies widely among providers. Computer-based sedation models have the potential to assist sedation providers and offer a more consistent and safer sed... περισσότερα »

Salivary Intercalated Duct Lesions in Transition

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 13 δευτερόλεπτα
Salivary Intercalated Duct Lesions in Transition: Abstract We read with great interest the article, “Tubular variant of basal cell adenoma shares immunophenotypical features with normal intercalated ducts and is closely related to intercalated duct lesions of salivary gland,” by Montalli et al.1 We agree entirely that intercalated duct lesions (IDL) may be precursors to basal cell adenoma (BCA). The authors demonstrate a close morphologic and immunophenotypic overlap with IDL and tubular variant of BCA in particular. However, they also note focal IDL like areas in ‘non-tubular’ BCA... περισσότερα »

The clinical analysis of bilateral successive sudden sensorineural hearing loss.

Alexandros G. SfakianakisστοThyroid Disorders by Alexandros G.SfakianakisΠριν από 14 δευτερόλεπτα
*The clinical analysis of bilateral successive sudden sensorineural hearing loss.* Eur Arch Otorhinolaryngol. 2016 Apr 6; Authors: Wang Y, Zhang L, Zhang J, Zhang X, Zhang W, Chen X, Tang S Abstract The objective of this study is to investigate the clinical characteristics of successive bilateral sudden sensorineural hearing loss (SSNHL) with an interval of more than 1 year to aid the evaluation and management of successive bilateral SSNHL (BSSNHL). 14 successive BSSNHL patients and 118 unilateral SSNHL patients with severe and profound hearing loss were reviewed retrospectively....περισσότερα »

One Year Effects of a Workplace Integrated Care Intervention for Workers with Rheumatoid Arthritis: Results of a Randomized Controlled Trial

Alexandros G. SfakianakisστοΒιοΜηχανικήΠριν από 16 δευτερόλεπτα
Abstract *Purpose* To evaluate the effectiveness of a workplace integrated care intervention on at-work productivity loss in workers with rheumatoid arthritis (RA) compared to usual care. *Methods* In this randomized controlled trial, 150 workers with RA were randomized into either the intervention or control group. The intervention group received an integrated care and participatory workplace intervention. Outcome measures were the Work Limitations Questionnaire, Work Instability Scale for RA, pain, fatigue and quality of life (RAND 36). Participants filled out a questionnaire at... περισσότερα »

Targeted delivery of microRNA-126 to vascular endothelial cells via REDV peptide modified PEG-trimethyl chitosan

Alexandros G. SfakianakisστοΒιοΜηχανικήΠριν από 16 δευτερόλεπτα
[image: GA?id=C5BM00629E] *Biomater. Sci.*, 2016, Advance Article *DOI*: 10.1039/C5BM00629E, Paper Fang Zhou, Xiaoling Jia, Qingmao Yang, Yang Yang, Yunhui Zhao, Yubo Fan, Xiaoyan Yuan Cationic complexes self-assembled from REDV peptide-modified PEG-trimethyl chitosan (TMC-*g*-PEG-REDV) polyplexes show efficient targeted delivery of miRNA-126 to vascular endothelial cells (VECs). To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry from Biomedical Engineering via xlomafota13 on Ino... περισσότερα »

Prevalence of Leprous Neuropathy determined by Neurosensory Testing in an Endemic Zone in Ecuador: Development of an Algorithm to Identify Who might benefit from Early Neurolysis

Alexandros G. SfakianakisστοΚοσμητική και Επανορθωτική ΧειρουργικήΠριν από 17 δευτερόλεπτα
Publication date: Available online 7 April 2016 *Source:*Journal of Plastic, Reconstructive & Aesthetic Surgery Author(s): Pablo A. Baltodano, Danielle H. Rochlin, Jonathan Noboa, Karim A. Sarhane, Gedge D. Rosson, A.Lee Dellon The potential for successful microneurosurgical intervention in leprous neuropathy (LN) depends upon diagnosis of chronic compression before irreversible paralysis and digital loss occurs. To determine utility of a different approach to early identification of LN, neurosensory testing with the Pressure-Specified Sensory DeviceTM (PSSD), a validated, sensitive ...περισσότερα »

The use of electrodessication in the treatment of cutaneous neurofibromatosis: a retrospective patient satisfaction outcome assessment

Alexandros G. SfakianakisστοΚοσμητική και Επανορθωτική ΧειρουργικήΠριν από 17 δευτερόλεπτα
Publication date: Available online 7 April 2016 *Source:*Journal of Plastic, Reconstructive & Aesthetic Surgery Author(s): C.G. Lutterodt, A. Mohan, N. Kirkpatrick IntroductionNF-1 is an autosomal dominant disease that can give rise to hundreds of cutaneous neurofibromas. In addition to localised symptoms such as pain and pruritus these lesions can have a devastating psychosocial impact. To date there is no consensus on the optimal management of these lesions. We present clinical and patient reported outcomes of a series of NF-1 patients treated with electrodessication by one surgeon...περισσότερα »

Ponticulus Posticus : a partial or complete bony arch over the vertebral artery as it crosses the superolateral surface of the posterior arch of the atlas

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 17 δευτερόλεπτα
Prevalence of ponticulus posticus in a Northern Italian orthodontic population: a lateral cephalometric study: Abstract PurposeThe term “ponticulus posticus” refers to a partial or complete bony arch over the vertebral artery as it crosses the superolateral surface of the posterior arch of the atlas. This anatomical modification is linked to different symptoms, ranging from neckache to headache and migraine. This bony arch may also be incorrectly assessed during orthopaedic surgery for fixation of C1–C2, with consequent risk of damaging the vertebral artery. Its frequency in the g... περισσότερα »

The superior cervical ganglion and its surrounding structures

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 17 δευτερόλεπτα
A morphometric analysis of the superior cervical ganglion and its surrounding structures: Abstract PurposeThe aim of this cadaveric study was to detect the superior cervical ganglion (SCG) in a topographic manner according to vertebrae and to determine the relationship between the vertebrae, mandibular angle and longus colli muscle through morphometric analysis. MethodsThe present study was performed on 40 SCG of 20 human cadavers (16 males, 4 females). The level of the SCG was determined based on the vertebrae. Ganglion length, width and thickness were detected. Distance to t... περισσότερα »

August Hirt (1898-1945) was director of the Institute of Anatomy of the Reichsuniversität Strassburg from November 1941 to November 1944

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 18 δευτερόλεπτα
Anatomy in the Third Reich - The Anatomical Institute of the Reichsuniversität Strassburg and the deliveries of dead bodies via ScienceDirect Publication: Annals of Anatomy - Anatomischer Anzeiger Publication date: Available online 6 April 2016 *Source:*Annals of Anatomy - Anatomischer Anzeiger Author(s): Raphael Toledano August Hirt (1898-1945) was director of the Institute of Anatomy of the Reichsuniversität Strassburg from November 1941 to November 1944. During this period, he was involved in many criminal activities: mustard gas experiments on prisoners of KL Natzweiler-Struthof, cr... περισσότερα »

Rosai-Dorfman type histiocytes occur in eosinophilic chronic rhinosinusitis

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 18 δευτερόλεπτα
and potentially play a role in disease initiation and persistence: Abstract Aims We recently identified the presence of Rosai-Dorfman type histiocytes (RDH) in sinonasal tissue removed from individuals with eosinophilic chronic rhinosinusitis (ECR). We sought to determine their clinical significance. Methods and results Sinonasal biopsies from ten individuals (index cases) with classical features of ECR and the additional finding of RDH were collected over a two and a half year period. Twenty-one sinonasal biopsies with a diagnosis of ECR accrued over a six-month period were reviewe... περισσότερα »

Early detection of hearing loss

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 18 δευτερόλεπτα
Retraso en el diagnóstico de sordera infantil: el valor de los falsos negativos en el Programa de Detección Precoz de Hipoacusias Neonatales via Acta Otorrinolaringológica Española Publication date: Available online 6 April 2016 *Source:*Acta Otorrinolaringológica Española Author(s): María C. Martínez-Pacheco, Luis Ferrán de la Cierva, Francisco J. García-Purriños IntroducciónA pesar de su importancia, la existencia de falsos negativos (pacientes a los que se les dice que oyen bien, pero en realidad son hipoacúsicos) no suele ser evaluada en los programas de detección precoz de hipoacu... περισσότερα »

Increased Exhaled 8-Isoprostane and Interleukin-6 in Patients with Helicobacter pylori Infection

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 18 δευτερόλεπτα
Increased Exhaled 8-Isoprostane and Interleukin-6 in Patients with Helicobacter pylori Infection: Abstract Background *Helicobacter pylori* (*H. pylori*) infection triggers both local inflammation, usually in gastric mucosa, and chronic systemic inflammation. It is assumed that this local and systemic inflammation is caused by extracellular products excreted by *H. pylori*. The aim of this study was to investigate the possible association between *H. pylori* infection and a local inflammatory response in the airway by using exhaled breath condensate technique. Materials and Methods... περισσότερα »

A 21–35 kDa Mixed Protein Component from Helicobacter pylori Activates Mast Cells Effectively in Chronic Spontaneous Urticaria

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 18 δευτερόλεπτα
A 21–35 kDa Mixed Protein Component from Helicobacter pylori Activates Mast Cells Effectively in Chronic Spontaneous Urticaria: Abstract Background *Helicobacter pylori* (*H. pylori*) seem to involve in the etiology of chronic spontaneous urticaria (CSU). But studies of the pathogenic mechanism are very little. Methods In this study, we detected the serum-specific anti-*H. pylori* IgG and IgE antibodies in 211 CSU and 137 normal subjects by enzyme-linked immunosorbent assay (ELISA), evaluated the direct activation effects of *H. pylori* preparations and its protein components on hum...περισσότερα »

Secondhand smoke and rhinitis.

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 18 δευτερόλεπτα
Secondhand smoke and rhinitis.: Purpose of review: The article reviews the most recent literature on the association between secondhand tobacco smoke exposure and rhinitis. The discussion will focus on the biologic links between tobacco exposure and rhinitis symptoms, evaluating this relationship in different populations. Recent findings: Significant associations between tobacco smoke exposure and rhinitis symptoms have been identified in US children and adults. This association is not just a US public health concern, as similar analyses have also recently been performed in other po...περισσότερα »

Research into the prevention and rehabilitation of dysphagia in head and neck cancer

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 23 δευτερόλεπτα
: a UK perspective.: Purpose of review: There is an increasing recognition of dysphagia as a frequent, often severe and chronic side-effect of head and neck cancer treatment. There has been a global increase in the number of head and neck cancer survivors, increasing the urgency of finding ways to best manage swallowing difficulties. Recent findings: There are several research studies investigating strategies and developing interventions to prevent and treat this debilitating condition. The United Kingdom has a growing number of trials and feasibility studies in this area, which hav... περισσότερα »

Earplugs in Preventing Recreational Noise-Induced Hearing Loss

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 24 δευτερόλεπτα
A Randomized Clinical Trial.: *Effectiveness of Earplugs in Preventing Recreational Noise-Induced Hearing Loss: A Randomized Clinical Trial.* JAMA Otolaryngol Head Neck Surg. 2016 Apr 7; Authors: Ramakers GG, Kraaijenga VJ, Cattani G, van Zanten GA, Grolman W Abstract Importance: The incidence of hearing loss has risen in past years. Attendance at music festivals and concerts may contribute to this increasing problem. Objective: To assess the effectiveness of earplugs in preventing temporary hearing loss immediately following music exposure. Design, Setting, and Participants: A ...περισσότερα »

Endoscopic endonasal approach to pituitary adenomas

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 24 δευτερόλεπτα
Impact of nasoseptal flap elevation on sinonasal quality of life in endoscopic endonasal approach to pituitary adenomas: AbstractTo evaluate the impact of nasoseptal flap (NSF) elevation on sinonasal quality of life (QOL) in patients with pituitary adenomas who underwent endoscopic endonasal trans-sphenoidal approach (EETSA), the data of 106 eligible patients were included from February 2011 to December 2014. The scores of Sinonasal Outcome Test (SNOT-22) Questionnaire were assessed in case (that received reconstruction with NSF) and control groups preoperatively as well as 1, 3, 6...περισσότερα »

Decision making in dissection range of temporal bone

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 24 δευτερόλεπτα
: refinements to enlarged translabyrinthine approach: AbstractThe aim of the study was to describe the refinements to the classic enlarged translabyrinthine approach (ETLA) by modifying the bony dissection range of temporal bone and to analyze the main outcomes achieved in a series of vestibular schwannoma (VS) cases submitted to microsurgery by ETLA. This was a retrospective study of 382 patients who underwent VS surgical removal via ETLA between January 2001 and December 2012. Among those cases, 332 were via classic ETLA, while 28 cases were via ETLA with blind sac technique and ... περισσότερα »

Esthesioneuroblastoma with large intracranial extension

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 25 δευτερόλεπτα
treated with Induction chemotherapy, de-bulking surgery and image guided intensity modulated radiotherapy: Abstract IntroductionEsthesioneuroblastoma is a rare tumour of the sino-nasal tract. One-third cases present with intracranial extension. However, treatment options are limited for such cases. MethodologyWe herein report a case with large intracranial extension treated with Induction chemotherapy, de-bulking surgery, and image guided intensity modulated radiotherapy. ResultsThe patient was treated with IGIMRT technique to a dose of 64 Gy in 32 fractions. Cone bean CT ...περισσότερα »

The use of NiTiBOND versus Nitinol prostheses in stapes surgery

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 26 δευτερόλεπτα
Comparison of hearing results following the use of NiTiBOND versus Nitinol prostheses in stapes surgery: a retrospective controlled study reporting short-term postoperative results: AbstractThe aim of this retrospective study was to compare the 3-month postoperative hearing results following laser stapedotomy with the use of NiTiBOND versus Nitinol prostheses (31 and 39 patients, respectively). The operations were performed between September 2012 and September 2014, and between March 2006 and December 2012 regarding NiTiBOND and Nitinol, respectively. Twenty of the consecutive 31 p...περισσότερα »

Antibiotic efficacy in patients with a moderate probability of acute rhinosinusitis

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 26 δευτερόλεπτα
: a systematic review: AbstractThe aim of this systematic review was to synthesize the results of original studies assessing antibiotic efficacy at different time points after initiating treatment in patients with a moderate probability of acute bacterial rhinosinusitis. We searched the Cochrane library for systematic reviews on the efficacy of antibiotic treatment in patients with acute rhinosinusitis (ARS). Only randomized controlled trials (RCTs) that compared treatment of any antibiotic with placebo were included. The synthesis of the results of six RCTs showed a benefit of ant... περισσότερα »

The European Board of Otorhinolaryngology-Head and Neck Surgery Examination (EBEORL-HNS)

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 27 δευτερόλεπτα
The development and design of The UEMS Otorhinolaryngology-Head and Neck Surgery section is a dedicated body formed to promote the standardisation and harmonisation of European Otorhinolaryngology (ORL). The European Examination Board of Otorhinolaryngology and Head and Neck Surgery was created to establish a supranational final exam and accreditation for ORL Surgeons. It is open to candidates both from the European Union and outside the EU. The exam is composed of a written examination to assess mainly the theoretical knowledge of Otorhinolaryngological diseases. The second part... περισσότερα »

TMPRSS3 mutations in autosomal recessive nonsyndromic hearing loss

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 27 δευτερόλεπτα
TMPRSS3 mutations in autosomal recessive nonsyndromic hearing loss: AbstractNonsyndromic genetic deafness is highly heterogeneous in its clinical presentation, pattern of inheritance and underlying genetic causes. Mutations in *TMPRSS3* gene encoding transmembrane serine protease account for <1 % of autosomal recessive nonsyndromic hearing loss (ARNSHL) in Caucasians. Targeted next generation sequencing in the index family with profound deaf parents and a son, and Sanger sequencing of selected *TMPRSS3* gene regions in a cohort of thirty-five patients with suspected ARNSHL was adop... περισσότερα »

Four-phase rhinomanometry

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 27 δευτερόλεπτα
: a multicentric retrospective analysis of 36,563 clinical measurements: AbstractRhinomanometry can still be considered as the standard technique for the objective assessment of the ventilatory function of the nose. Reliable technical requirements are given by fast digital sensors and modern information technology. However, the xyimaging of the pressure-flow relation typically shows loops as a sign of hysteresis, with the need for resolution of the breath in four phases. The three pillars of 4-phase rhinomanometry (4PR) are the replacement of estimations by measurements, the introd... περισσότερα »

GJB2 mutations in deaf population

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 27 δευτερόλεπτα
of Ilam (Western Iran): a different pattern of mutation distribution: AbstractHearing loss is the most common sensory defect caused by heterogeneous factors. Up to now, more than 60 mutations in genes have been documented for nonsyndromic hearing loss. Hence, finding the causal gene in affected families could be a laborious and time-consuming process. GJB2 mutations, here, were investigated among deaf subjects of Ilam for the first time. In this study, we studied 62 unrelated patients with non-syndromic autosomal recessive deafness from 62 families. The most common mutation of GJB...περισσότερα »

Nasal mucociliary activity in patients with chronic renal failure

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 27 δευτερόλεπτα
Evaluation of AbstractThe ability of respiratory mucosal surfaces to eliminate foreign particles and pathogens and to keep mucosal surfaces moist and fresh depends on mucociliary activity. Chronic renal failure (CRF) is an irreversible medical condition that may result in important extrarenal systemic consequences, such as cardiovascular, metabolic, and respiratory system abnormalities. Although there are studies describing nasal manifestations of CRF, data are lacking concerning the effects of the condition on nasal mucosa. The goal of the current study was to evaluate nasal mucoc...περισσότερα »

Childhood hearing surveillance activity in Italy: preliminary recommendations.

Alexandros G. SfakianakisστοΑκοή και ΙσορροπίαΠριν από 27 δευτερόλεπτα
*Childhood hearing surveillance activity in Italy: preliminary recommendations.* Acta Otorhinolaryngol Ital. 2016 Feb;36(1):15-20 Authors: Orzan E, Ruta F, Bolzonello P, Marchi R, Ceschin F, Ciciriello E Abstract Following the positive outcomes of the newborn hearing screening programmes already underway in several Italian regions, it is now necessary to address the identification of childhood hearing impairments that missed the neonatal screening programme or have delayed onset. Within the framework of the Ministry of Health project CCM 2013 "Preventing Communication Disorders: ...περισσότερα »

Hearing Profile in Patients with Dilated and Hypertrophic Cardiomyopathies.

Alexandros G. SfakianakisστοΑκοή και ΙσορροπίαΠριν από 27 δευτερόλεπτα
*Hearing Profile in Patients with Dilated and Hypertrophic Cardiomyopathies.* Electron Physician. 2016 Feb;8(2):2030-8 Authors: El-Zarea GA, Hassan YE, Mahmoud AM Abstract INTRODUCTION: Cardiomyopathy may cause disruptions in the micro-vascular system of the stria vascularis in the cochlea, and, subsequently, may result in cochlear degeneration. Degeneration in the stria vascularis affects the physical and chemical processes in the organ of Corti, thereby causing a possible hearing impairment. The objective of this study was to assess the hearing profiles of patients with dilated...περισσότερα »

One staged multilevel surgery with tongue suspension surgery or one level palatal surgery for treatment of moderate and severe obstructive sleep apnea

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 28 δευτερόλεπτα
Long-term results of AbstractThe objective of this study is to evaluate and compare the long-term efficacy of the one staged multilevel surgery (MLS) with tongue suspension (TBS) surgery or one level palatal surgery for treatment of moderate and severe obstructive sleep apnea (OSA). This is a prospective cross-sectional study. Setting: University hospital. Thirty-three patients diagnosed as moderate to severe OSA. Patients, with ≥50 % retropalopharyngeal obstruction on the Müller maneuver, were treated with palatal surgeries (PS) and patients, with ≥50 % retropalopharyngeal obstru... περισσότερα »

Speech recognition outcomes following bilateral cochlear implantation

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 28 δευτερόλεπτα
in adults aged over 50 years old: 10.3109/14992027.2016.1152403<br>Isabelle Boisvert Abstract *Objective*: To examine the speech recognition benefit of bilateral cochlear implantation over unilateral implantation in adults aged over 50 years old, and to identify potential predictors of successful bilateral implantation in this group. *Design*: Retrospective cohort study using data collected during standard clinical practice. Bilateral performance was compared to the unilateral performance with the first and second implanted ear and examined in relation to potential predictive v... περισσότερα »

Auditory steady-state responses amplitude evoked by simultaneous air- and bone-conducted stimulation in newborns

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 28 δευτερόλεπτα
Comparing auditory steady-state responses amplitude evoked by simultaneous air- and bone-conducted stimulation in newborns: 10.3109/14992027.2016.1159341<br>Alejandro Torres-Fortuny Abstract *Objective*: The aim of this study was to evaluate the potential interactions of the simultaneous presentation of air- and bone-conducted stimuli on auditory steady-state responses (ASSR) amplitude in newborns. *Design:* Bone- and air-conducted stimuli were sinusoidal carrier tones of 500 and 2000 Hz respectively modulated in amplitude (95% depth). Air- and bone- conducted stimuli were eithe...περισσότερα »

Normal mode solutions for seismo-acoustic propagation resulting from shear and combined wave point sources

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 28 δευτερόλεπτα
Normal mode solutions for seismo-acoustic propagation resulting from shear and combined wave point sources: [image: cm_sbs_024_plain.png] Normal modesolutions to range-independent seismo-acoustic problems are benchmarked against elastic parabolic equation solutions and then used to benchmark the shear elastic parabolic equation self-starter [Frank, Odom, and Collis, J. Acoust. Soc. Am. 133, 1358–1367 (2013)]. The Pekeris waveguide with an elastic seafloor is considered for a point source located in the ocean emitting compressional waves, or in the seafloor, emitting both compressi... περισσότερα »

Aerial pollen diversity in Punjab and their clinical significance in allergic diseases

orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 29 δευτερόλεπτα
Abstract The present study has been carried out to assess the allergenicity of dominant pollen types from the atmosphere of nine districts of the state of Punjab, India. During the study period (2012–2014), 30 different kinds of pollens belonging to 17 families were recorded. Antigenic extract of thirteen pollen types were selected for skin prick… Continue reading Aerial pollen diversity in Punjab and their clinical significance in allergic diseases

Gray matter abnormality predicts neurodevelopmental problems in smaller premature babies

orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 29 δευτερόλεπτα
Magnetic resonance imaging of the brain is increasingly used to predict neurodevelopmental outcomes in premature infants, but the existing systems of analyzing or «scoring» those MRIs rely heavily… from #Medicine-Sfakianakis via simeraentaxei on Inoreader http://ift.tt/20dAJQE via IFTTT

Long-term results of one staged multilevel surgery with tongue suspension surgery or one level palatal surgery for treatment of moderate and severe obstructive sleep apnea

orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 29 δευτερόλεπτα
Abstract The objective of this study is to evaluate and compare the long-term efficacy of the one staged multilevel surgery (MLS) with tongue suspension (TBS) surgery or one level palatal surgery for treatment of moderate and severe obstructive sleep apnea (OSA). This is a prospective cross-sectional study. Setting: University hospital. Thirty-three patients diagnosed as moderate… Continue reading Long-term results of one staged multilevel surgery with tongue suspension surgery or one level palatal surgery for treatment of moderate and severe obstructive sleep apnea

Evaluation of nasal mucociliary activity in patients with chronic renal failure

orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 29 δευτερόλεπτα
Abstract The ability of respiratory mucosal surfaces to eliminate foreign particles and pathogens and to keep mucosal surfaces moist and fresh depends on mucociliary activity. Chronic renal failure (CRF) is an irreversible medical condition that may result in important extrarenal systemic consequences, such as cardiovascular, metabolic, and respiratory system abnormalities. Although there are studies describing… Continue reading Evaluation of nasal mucociliary activity in patients with chronic renal failure

GJB2 mutations in deaf population of Ilam (Western Iran): a different pattern of mutation distribution

orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 29 δευτερόλεπτα
Abstract Hearing loss is the most common sensory defect caused by heterogeneous factors. Up to now, more than 60 mutations in genes have been documented for nonsyndromic hearing loss. Hence, finding the causal gene in affected families could be a laborious and time-consuming process. GJB2 mutations, here, were investigated among deaf subjects of Ilam for… Continue reading GJB2 mutations in deaf population of Ilam (Western Iran): a different pattern of mutation distribution

Four-phase rhinomanometry: a multicentric retrospective analysis of 36,563 clinical measurements

orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 29 δευτερόλεπτα
Abstract Rhinomanometry can still be considered as the standard technique for the objective assessment of the ventilatory function of the nose. Reliable technical requirements are given by fast digital sensors and modern information technology. However, the xyimaging of the pressure-flow relation typically shows loops as a sign of hysteresis, with the need for resolution of… Continue reading Four-phase rhinomanometry: a multicentric retrospective analysis of 36,563 clinical measurements

Brånemark’s legacy

orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 29 δευτερόλεπτα
from #Medicine-Sfakianakis via simeraentaxei on Inoreader http://ift.tt/25P5b7J via IFTTT

The SLEEP GOAL as a success criteria in obstructive sleep apnea therapy

orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 29 δευτερόλεπτα
from #Medicine-Sfakianakis via simeraentaxei on Inoreader http://ift.tt/1RUCYms via IFTTT

TMPRSS3 mutations in autosomal recessive nonsyndromic hearing loss

orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 29 δευτερόλεπτα
Abstract Nonsyndromic genetic deafness is highly heterogeneous in its clinical presentation, pattern of inheritance and underlying genetic causes. Mutations in TMPRSS3 gene encoding transmembrane serine protease account for &lt;1 % of autosomal recessive nonsyndromic hearing loss (ARNSHL) in Caucasians. Targeted next generation sequencing in the index family with profound deaf parents and a son, and… Continue reading TMPRSS3 mutations in autosomal recessive nonsyndromic hearing loss

The development and design of the European Board of Otorhinolaryngology-Head and Neck Surgery Examination (EBEORL-HNS)

orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 29 δευτερόλεπτα
Abstract The UEMS Otorhinolaryngology-Head and Neck Surgery section is a dedicated body formed to promote the standardisation and harmonisation of European Otorhinolaryngology (ORL). The European Examination Board of Otorhinolaryngology and Head and Neck Surgery was created to establish a supranational final exam and accreditation for ORL Surgeons. It is open to candidates both from the… Continue reading The development and design of the European Board of Otorhinolaryngology-Head and Neck Surgery Examination (EBEORL-HNS)

Accuracy comparison of guided surgery for dental implants according to the tissue of support: a systematic review and meta-analysis

Alexandros G. SfakianakisστοOroFacial Medicine by Alexandros G.SfakianakisΠριν από 29 δευτερόλεπτα
[image: cover.gif?v=1&amp;s=ea3ed681cef4af2a1760b136] Abstract Aim To systematically assess the current dental literature comparing the accuracy of computer-aided implant surgery when using different supporting tissues (tooth, mucosa, or bone). Material and Methods Two reviewers searched PubMed (1972 to January 2015) and the Cochrane Central Register of Controlled Trials (Central) (2002 to January 2015). For the assessment of accuracy, studies were included with the following outcome measures: (i) angle deviation, (ii) deviation at the entry point, and (iii) deviation at the apex. ...περισσότερα »

Unusual Presenting Tadpole-Shaped Dermoid Cyst on Eyebrow.

Alexandros G. SfakianakisστοOroFacial Medicine by Alexandros G.SfakianakisΠριν από 29 δευτερόλεπτα
Dermoid cysts are embryonic lesions that are usually observed in the lateral eyebrow region and the midlines of the nose and neck; they contain an epithelial lining and adnexal structures, and are typically round or oval shaped. If ruptured, an inflammatory response can occur in the area surrounding the cyst, which can also induce pain, while the locations around intracranial and intraspinal extensions have a higher risk of inflammation; therefore, a definitive diagnosis is important. In this study, we report the case of a 6-year-old patient who had a remarkable, tadpole-shaped derm... περισσότερα »

Papillary Carcinoma Within a Thyroglossal Duct Cyst in a 17-Year-Old Child.

Alexandros G. SfakianakisστοOroFacial Medicine by Alexandros G.SfakianakisΠριν από 29 δευτερόλεπτα
Thyroglossal duct cyst is a frequent event; however, papillary carcinoma within a thyroglossal duct cyst is rare, particularly in children. A 17-year-old girl presented with an asymptomatic mid-submental mass for the last 2 months. The diagnosis of thyroglossal duct cyst was made based on physical examination and computed tomography finding. After performance of Sistrunk procedure, an incidental papillary carcinoma within the thyroglossal duct cyst was observed on pathology. We reviewed the pediatric cases of thyroglossal duct carcinoma, and then decided not to perform a concurrent ... περισσότερα »

Effect of an Activated Platelet Concentrate on Differentiated Cells Involved in Tissue Healing.

Alexandros G. SfakianakisστοOroFacial Medicine by Alexandros G.SfakianakisΠριν από 29 δευτερόλεπτα
Tissue healing is a complex process involving several players such as cells and growth factors released from platelets upon activation. Today, platelet concentrates (PCs) are used in many different medical fields including oral, orthopaedic, and reconstructive surgery since they allow growth factors delivery to the injured site, aiming at enhancing tissue regeneration. The purpose of this in vitro study was to evaluate the effect of the acellular plasma of an activated platelet concentrate obtained using a manual protocol, on the proliferation, and biological activity of differentia... περισσότερα »

Unilateral Le Fort I Osteotomy for Rehabilitating the Large Alveolar Cleft and Vertical Malocclusion With the Distraction Technique.

Alexandros G. SfakianakisστοOroFacial Medicine by Alexandros G.SfakianakisΠριν από 29 δευτερόλεπτα
Rehabilitation of the large alveolar clefts with autogenous graft or distraction osteogenesis is one of the most common treatment choices. Depending on the clinical situation such as vertical deficiencies, linear transport of the segment does not always ensure a proper closure of the cleft space. In this report, the authors present a patient in whom large unilateral cleft and vertical alveolar deficiency were closed by unilateral Le Fort I osteotomy and distraction technique using the orthodontic elastics. (C) 2016 by Mutaz B. Habal, MD. from OroFacial Medicine via ola Kala on Inore... περισσότερα »

Polyurethane Foam-Filled Skull Replica of Craniosynostosis for Surgical Training.

Alexandros G. SfakianakisστοOroFacial Medicine by Alexandros G.SfakianakisΠριν από 29 δευτερόλεπτα
Craniosynostosis has a relatively low incidence in the general population and its treatment requires cautious approaches. For these reasons, patients are usually referred to several specialists or a medical center. Therefore, most trainees and young surgeons do not have any chances to experience patients of craniosynostosis, but learn about it only from textbooks. And for a surgeon who tries to operate on a craniosynostosis patient, it is hard to make a proper preoperative plan. The authors suggest a polyurethane foam-filled skull replica of craniosynostosis for trainees that can als... περισσότερα »

Diffuse ultrasound monitoring of stress and damage development

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 30 δευτερόλεπτα
on a 15-ton concrete beam: [image: cm_sbs_024_plain.png] This paper describes the use of an ultrasonic imaging technique (Locadiff) for the Non-Destructive Testing &amp; Evaluation of a concrete structure. By combining coda wave interferometry and a sensitivity kernel for diffuse waves, Locadiff can monitor the elastic and structural properties of a heterogeneous material with a high sensitivity, and can map changes of these properties over time when a perturbation occurs in the bulk of the material. The applicability of the technique to life-size concrete structures is demonstrated ... περισσότερα »

Vowel-dependent variation in Cantonese /s/ from an individual-difference perspective

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 30 δευτερόλεπτα
Vowel-dependent variation in Cantonese /s/ from an individual-difference perspective: [image: cm_sbs_024_plain.png] Individual variation is ubiquitous in the acoustic realization of human speech; however, little is known about the nature of individual differences in coarticulation. Through an in-depth case study of the temporal dynamics of vocalic influences on the acoustic realization of Cantonese /s/, this study demonstrates that coarticulatory effects may vary by the sex and self-reported autistic-like traits of the individual. These findings have significant implications for r... περισσότερα »

Adenosine-mediated immunosuppression in patients with squamous cell carcinoma of the head and neck.

Alexandros G. SfakianakisστοHead,Neck,Brain,Cervical Spine and Esophageal Cancers by Alexandros G. SfakianakisΠριν από 31 δευτερόλεπτα
*Adenosine-mediated immunosuppression in patients with squamous cell carcinoma of the head and neck.* HNO. 2016 Apr 6; Authors: Mandapathil M Abstract This review article describes the potential role of ectonucleotidase activity, adenosine metabolism, and the adenosinergic signaling pathway in the suppression of the host immune system in patients with head and neck cancer. Identifying such mechanisms leads to a better understanding of immunosuppressive mechanisms in this patient population. Further, potential targets for immunotherapy in an adjuvant approach to treating squamous ...περισσότερα »

The Visual Attention Patterns of People With Aphasia and Adults Without Neurological Conditions for Camera-Engaged and Task-Engaged Visual Scenes

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 31 δευτερόλεπτα
A Comparison of the Visual Attention Patterns of People With Aphasia and Adults Without Neurological Conditions for Camera-Engaged and Task-Engaged Visual Scenes: Purpose The purpose of the study was to compare the visual attention patterns of adults with aphasia and adults without neurological conditions when viewing visual scenes with 2 types of engagement. Method Eye-tracking technology was used to measure the visual attention patterns of 10 adults with aphasia and 10 adults without neurological conditions. Participants viewed camera-engaged (i.e., human figure facing camera) a...περισσότερα »

Tinnitus

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 31 δευτερόλεπτα
Is Tinnitus Treatable?: Tinnitus is one of the most intrusive disorders known in our modern society. It is far more prevalent today than ever before due to the fact that society is noisier than ever before. Construction workers, factory workers and disc jockeys are probably the three occupations most effected by tinnitus. Loud sounds without proper ear protection can cause tinnitus, and once you have it, it usually does not go away. And while there is no cure currently known, the question is: is tinnitus treatable? *Disc Jockeys Beware* If you are in an otherwise quiet room and yo... περισσότερα »

The Effect of Microphone Placement on Interaural Level Differences and Sound Localization Across the Horizontal Plane in Bilateral Cochlear Implant Users.

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 31 δευτερόλεπτα
The Effect of Microphone Placement on Interaural Level Differences and Sound Localization Across the Horizontal Plane in Bilateral Cochlear Implant Users.: The effect of microphone placement on the interaural level differences available to bilateral cochlear implant users, and subsequent effects on horizontal-plane sound localization were investigated. Presently, microphones are most commonly placed behind the ear in adults, and sometimes on the shoulders in children. While efforts to position microphones in the ear exist, the impact of such placements on sound localization in bilat... περισσότερα »

Hearing Profile in Patients with Dilated and Hypertrophic Cardiomyopathies.

Alexandros G. SfakianakisστοOtoRhinoLaryngology - Alexandros G. SfakianakisΠριν από 32 δευτερόλεπτα
Hearing Profile in Patients with Dilated and Hypertrophic Cardiomyopathies.: Electron Physician. 2016;8(2):2030-8 Authors: El-Zarea GA, Hassan YE, Mahmoud AM Abstract INTRODUCTION: Cardiomyopathy may cause disruptions in the micro-vascular system of the stria vascularis in the cochlea, and, subsequently, may result in cochlear degeneration. Degeneration in the stria vascularis affects the physical and chemical processes in the organ of Corti, thereby causing a possible hearing impairment. The objective of this study was to assess the hearing profiles of patients with dilated and hy...περισσότερα »

Intraprocedural fluoroscopy to determine the extent of the cardiomyotomy during per-oral endoscopic myotomy (with video).

Alexandros G. SfakianakisστοSwallowing and Swallowing Disorders (Dysphagia)Πριν από 37 δευτερόλεπτα
[image: http:--linkinghub.elsevier.com-ihub-imag] Related Articles *Intraprocedural fluoroscopy to determine the extent of the cardiomyotomy during per-oral endoscopic myotomy (with video).* Gastrointest Endosc. 2015;81(6):1451-6 Authors: Kumbhari V, Besharati S, Abdelgelil A, Tieu AH, Saxena P, El-Zein MH, Ngamruengphong S, Aguila G, Kalloo AN, Khashab MA Abstract BACKGROUND: An adequate myotomy on the gastric side is considered essential to optimize outcomes in patients undergoing per-oral endoscopic myotomy (POEM). An objective method to measure the length of gastric myotomy has...περισσότερα »

World Trade Center-related physical and mental health burden among New York City Fire Department emergency medical service workers.

Alexandros G. SfakianakisστοSwallowing and Swallowing Disorders (Dysphagia)Πριν από 37 δευτερόλεπτα
[image: http:--highwire.stanford.edu-icons-exter] Related Articles *World Trade Center-related physical and mental health burden among New York City Fire Department emergency medical service workers.* Occup Environ Med. 2016 Jan;73(1):13-20 Authors: Yip J, Zeig-Owens R, Webber MP, Kablanian A, Hall CB, Vossbrinck M, Liu X, Weakley J, Schwartz T, Kelly KJ, Prezant DJ Abstract OBJECTIVES: To describe the health burden among Fire Department of the City of New York (FDNY) emergency medical service (EMS) workers and examine its association with work at the World Trade Center (WTC) disas... περισσότερα »

Obstructive sleep apnea syndrome and gastroesophageal reflux disease: the importance of obesity and gender.

Alexandros G. SfakianakisστοSwallowing and Swallowing Disorders (Dysphagia)Πριν από 37 δευτερόλεπτα
[image: http:--production.springer.de-OnlineReso] Related Articles *Obstructive sleep apnea syndrome and gastroesophageal reflux disease: the importance of obesity and gender.* Sleep Breath. 2015 May;19(2):585-92 Authors: Basoglu OK, Vardar R, Tasbakan MS, Ucar ZZ, Ayik S, Kose T, Bor S Abstract BACKGROUND: It is claimed that gastroesophageal reflux disease (GERD) increases in patients with obstructive sleep apnea syndrome (OSAS). We aimed to evaluate the prevalence of GERD in patients with OSAS and primary snoring and identify OSAS-related risk factors associated with GERD. METHOD... περισσότερα »

An unusual case of progressive dysphagia.

Alexandros G. SfakianakisστοSwallowing and Swallowing Disorders (Dysphagia)Πριν από 37 δευτερόλεπτα
[image: http:--linkinghub.elsevier.com-ihub-imag] Related Articles *An unusual case of progressive dysphagia.* Gastroenterology. 2015 Nov;149(6):1337-8 Authors: Choe JW, Jung SW, Lee SW PMID: 26409240 [PubMed - indexed for MEDLINE] from Swallowing and Swallowing Disorders (Dysphagia) via xlomafota13 on Inoreader http://ift.tt/1RIbnIx

Increased risk of functional gastrointestinal sequelae after Clostridium difficile infection among active duty United States military personnel (1998-2010).

Alexandros G. SfakianakisστοSwallowing and Swallowing Disorders (Dysphagia)Πριν από 37 δευτερόλεπτα
[image: http:--linkinghub.elsevier.com-ihub-imag] Related Articles *Increased risk of functional gastrointestinal sequelae after Clostridium difficile infection among active duty United States military personnel (1998-2010).* Gastroenterology. 2015 Nov;149(6):1408-14 Authors: Gutiérrez RL, Riddle MS, Porter CK Abstract BACKGROUND &amp; AIMS: Some acute enteric infections are associated with the development of functional gastrointestinal disorders, most commonly irritable bowel syndrome but also other functional and organic gastrointestinal sequelae. Clostridium difficile infection has... περισσότερα »

Impaired upper esophageal sphincter reflexes in patients with supraesophageal reflux disease.

Alexandros G. SfakianakisστοSwallowing and Swallowing Disorders (Dysphagia)Πριν από 37 δευτερόλεπτα
[image: http:--linkinghub.elsevier.com-ihub-imag] Related Articles *Impaired upper esophageal sphincter reflexes in patients with supraesophageal reflux disease.* Gastroenterology. 2015 Nov;149(6):1381-91 Authors: Babaei A, Venu M, Naini SR, Gonzaga J, Lang IM, Massey BT, Jadcherla S, Shaker R Abstract BACKGROUND &amp; AIMS: Normal responses of the upper esophageal sphincter (UES) and esophageal body to liquid reflux events prevent esophagopharyngeal reflux and its complications, however, abnormal responses have not been characterized. We investigated whether patients with supraesopha... περισσότερα »

Rate of aspiration pneumonia in hospitalized Parkinson's disease patients: a cross-sectional study.

Alexandros G. SfakianakisστοSwallowing and Swallowing Disorders (Dysphagia)Πριν από 37 δευτερόλεπτα
[image: http:--http://ift.tt/1NMOrDk] [image: http:--http://ift.tt/1Fkw4zC] Related Articles *Rate of aspiration pneumonia in hospitalized Parkinson's disease patients: a cross-sectional study.* BMC Neurol. 2015;15:104 Authors: Martinez-Ramirez D, Almeida L, Giugni JC, Ahmed B, Higuchi MA, Little CS, Chapman JP, Mignacca C, Wagle Shukla A, Hess CW, Hegland KW, Okun MS Abstract BACKGROUND: Aspiration pneumonia is an important cause of morbidity and mortality in Parkinson's disease (PD). Clinical characteristics of PD patients in addition to specific alterations in swallowing mecha... περισσότερα »

It is not just IMRT: Human papillomavirus related oropharynx squamous cell carcinoma is associated with better swallowing outcomes after definitive chemoradiotherapy.

Alexandros G. SfakianakisστοSwallowing and Swallowing Disorders (Dysphagia)Πριν από 37 δευτερόλεπτα
[image: http:--linkinghub.elsevier.com-ihub-imag] Related Articles *It is not just IMRT: Human papillomavirus related oropharynx squamous cell carcinoma is associated with better swallowing outcomes after definitive chemoradiotherapy.* Oral Oncol. 2015 Aug;51(8):800-4 Authors: Naik M, Ward MC, Bledsoe TJ, Kumar AM, Rybicki LA, Saxton JP, Burkey BB, Greskovich JF, Adelstein DJ, Koyfman SA Abstract OBJECTIVES: Long term swallowing dysfunction in patients with oropharynx squamous cell carcinoma (OPSCC) treated with concurrent chemoradiation (CRT) is declining. While the use of intens... περισσότερα »

Intraprocedural fluoroscopy to determine the extent of the cardiomyotomy during per-oral endoscopic myotomy (with video).

Alexandros G. SfakianakisστοSwallowing and Swallowing Disorders (Dysphagia)Πριν από 37 δευτερόλεπτα
[image: http:--linkinghub.elsevier.com-ihub-imag] Related Articles *Intraprocedural fluoroscopy to determine the extent of the cardiomyotomy during per-oral endoscopic myotomy (with video).* Gastrointest Endosc. 2015;81(6):1451-6 Authors: Kumbhari V, Besharati S, Abdelgelil A, Tieu AH, Saxena P, El-Zein MH, Ngamruengphong S, Aguila G, Kalloo AN, Khashab MA Abstract BACKGROUND: An adequate myotomy on the gastric side is considered essential to optimize outcomes in patients undergoing per-oral endoscopic myotomy (POEM). An objective method to measure the length of gastric myotomy has...περισσότερα »

World Trade Center-related physical and mental health burden among New York City Fire Department emergency medical service workers.

Alexandros G. SfakianakisστοSwallowing and Swallowing Disorders (Dysphagia)Πριν από 37 δευτερόλεπτα
[image: http:--highwire.stanford.edu-icons-exter] Related Articles *World Trade Center-related physical and mental health burden among New York City Fire Department emergency medical service workers.* Occup Environ Med. 2016 Jan;73(1):13-20 Authors: Yip J, Zeig-Owens R, Webber MP, Kablanian A, Hall CB, Vossbrinck M, Liu X, Weakley J, Schwartz T, Kelly KJ, Prezant DJ Abstract OBJECTIVES: To describe the health burden among Fire Department of the City of New York (FDNY) emergency medical service (EMS) workers and examine its association with work at the World Trade Center (WTC) disas... περισσότερα »

Congenital vascular rings: a clinical challenge for the pediatrician.

Alexandros G. SfakianakisστοSwallowing and Swallowing Disorders (Dysphagia)Πριν από 37 δευτερόλεπτα
[image: http:--media.wiley.com-assets-7315-19-Wi] Related Articles *Congenital vascular rings: a clinical challenge for the pediatrician.* Pediatr Pulmonol. 2015 May;50(5):511-24 Authors: Licari A, Manca E, Rispoli GA, Mannarino S, Pelizzo G, Marseglia GL Abstract Vascular rings are congenital anomalies that lead to variable degrees of respiratory problems or feeding difficulties by forming a complete or partial ring compressing the trachea, the bronchi, and the esophagus. The clinical diagnosis of vascular rings is often challenging for the pediatrician because the clinical manife... περισσότερα »

Obstructive sleep apnea syndrome and gastroesophageal reflux disease: the importance of obesity and gender.

Alexandros G. SfakianakisστοSwallowing and Swallowing Disorders (Dysphagia)Πριν από 37 δευτερόλεπτα
[image: http:--production.springer.de-OnlineReso] Related Articles *Obstructive sleep apnea syndrome and gastroesophageal reflux disease: the importance of obesity and gender.* Sleep Breath. 2015 May;19(2):585-92 Authors: Basoglu OK, Vardar R, Tasbakan MS, Ucar ZZ, Ayik S, Kose T, Bor S Abstract BACKGROUND: It is claimed that gastroesophageal reflux disease (GERD) increases in patients with obstructive sleep apnea syndrome (OSAS). We aimed to evaluate the prevalence of GERD in patients with OSAS and primary snoring and identify OSAS-related risk factors associated with GERD. METHOD... περισσότερα »

Effect of dysphagia rehabilitation on oral intake in elderly patients with aspiration pneumonia.

Alexandros G. SfakianakisστοSwallowing and Swallowing Disorders (Dysphagia)Πριν από 37 δευτερόλεπτα
[image: http:--media.wiley.com-assets-7315-19-Wi] Related Articles *Effect of dysphagia rehabilitation on oral intake in elderly patients with aspiration pneumonia.* Geriatr Gerontol Int. 2015 Jun;15(6):694-9 Authors: Momosaki R, Yasunaga H, Matsui H, Horiguchi H, Fushimi K, Abo M Abstract AIM: To clarify the effects of dysphagia rehabilitation on oral intake after aspiration pneumonia in older adults. METHODS: The present retrospective observational study used data from the Japanese Diagnosis Procedure Combination inpatient database. We identified patients who were admitted to acu... περισσότερα »

An unusual case of progressive dysphagia.

Alexandros G. SfakianakisστοSwallowing and Swallowing Disorders (Dysphagia)Πριν από 37 δευτερόλεπτα
[image: http:--linkinghub.elsevier.com-ihub-imag] Related Articles *An unusual case of progressive dysphagia.* Gastroenterology. 2015 Nov;149(6):1337-8 Authors: Choe JW, Jung SW, Lee SW PMID: 26409240 [PubMed - indexed for MEDLINE] from Swallowing and Swallowing Disorders (Dysphagia) via xlomafota13 on Inoreader http://ift.tt/1RIbnIx

Increased risk of functional gastrointestinal sequelae after Clostridium difficile infection among active duty United States military personnel (1998-2010).

Alexandros G. SfakianakisστοSwallowing and Swallowing Disorders (Dysphagia)Πριν από 37 δευτερόλεπτα
[image: http:--linkinghub.elsevier.com-ihub-imag] Related Articles *Increased risk of functional gastrointestinal sequelae after Clostridium difficile infection among active duty United States military personnel (1998-2010).* Gastroenterology. 2015 Nov;149(6):1408-14 Authors: Gutiérrez RL, Riddle MS, Porter CK Abstract BACKGROUND &amp; AIMS: Some acute enteric infections are associated with the development of functional gastrointestinal disorders, most commonly irritable bowel syndrome but also other functional and organic gastrointestinal sequelae. Clostridium difficile infection has... περισσότερα »

Impaired upper esophageal sphincter reflexes in patients with supraesophageal reflux disease.

Alexandros G. SfakianakisστοSwallowing and Swallowing Disorders (Dysphagia)Πριν από 37 δευτερόλεπτα
[image: http:--linkinghub.elsevier.com-ihub-imag] Related Articles *Impaired upper esophageal sphincter reflexes in patients with supraesophageal reflux disease.* Gastroenterology. 2015 Nov;149(6):1381-91 Authors: Babaei A, Venu M, Naini SR, Gonzaga J, Lang IM, Massey BT, Jadcherla S, Shaker R Abstract BACKGROUND &amp; AIMS: Normal responses of the upper esophageal sphincter (UES) and esophageal body to liquid reflux events prevent esophagopharyngeal reflux and its complications, however, abnormal responses have not been characterized. We investigated whether patients with supraesopha... περισσότερα »

Rate of aspiration pneumonia in hospitalized Parkinson's disease patients: a cross-sectional study.

Alexandros G. SfakianakisστοSwallowing and Swallowing Disorders (Dysphagia)Πριν από 37 δευτερόλεπτα
[image: http:--http://ift.tt/1NMOrDk] [image: http:--http://ift.tt/1Fkw4zC] Related Articles *Rate of aspiration pneumonia in hospitalized Parkinson's disease patients: a cross-sectional study.* BMC Neurol. 2015;15:104 Authors: Martinez-Ramirez D, Almeida L, Giugni JC, Ahmed B, Higuchi MA, Little CS, Chapman JP, Mignacca C, Wagle Shukla A, Hess CW, Hegland KW, Okun MS Abstract BACKGROUND: Aspiration pneumonia is an important cause of morbidity and mortality in Parkinson's disease (PD). Clinical characteristics of PD patients in addition to specific alterations in swallowing mecha... περισσότερα »

It is not just IMRT: Human papillomavirus related oropharynx squamous cell carcinoma is associated with better swallowing outcomes after definitive chemoradiotherapy.

Alexandros G. SfakianakisστοSwallowing and Swallowing Disorders (Dysphagia)Πριν από 37 δευτερόλεπτα
[image: http:--linkinghub.elsevier.com-ihub-imag] Related Articles *It is not just IMRT: Human papillomavirus related oropharynx squamous cell carcinoma is associated with better swallowing outcomes after definitive chemoradiotherapy.* Oral Oncol. 2015 Aug;51(8):800-4 Authors: Naik M, Ward MC, Bledsoe TJ, Kumar AM, Rybicki LA, Saxton JP, Burkey BB, Greskovich JF, Adelstein DJ, Koyfman SA Abstract OBJECTIVES: Long term swallowing dysfunction in patients with oropharynx squamous cell carcinoma (OPSCC) treated with concurrent chemoradiation (CRT) is declining. While the use of intens... περισσότερα »

Intraprocedural fluoroscopy to determine the extent of the cardiomyotomy during per-oral endoscopic myotomy (with video).

Alexandros G. SfakianakisστοSwallowing and Swallowing Disorders (Dysphagia)Πριν από 37 δευτερόλεπτα
[image: http:--linkinghub.elsevier.com-ihub-imag] Related Articles *Intraprocedural fluoroscopy to determine the extent of the cardiomyotomy during per-oral endoscopic myotomy (with video).* Gastrointest Endosc. 2015;81(6):1451-6 Authors: Kumbhari V, Besharati S, Abdelgelil A, Tieu AH, Saxena P, El-Zein MH, Ngamruengphong S, Aguila G, Kalloo AN, Khashab MA Abstract BACKGROUND: An adequate myotomy on the gastric side is considered essential to optimize outcomes in patients undergoing per-oral endoscopic myotomy (POEM). An objective method to measure the length of gastric myotomy has...περισσότερα »

World Trade Center-related physical and mental health burden among New York City Fire Department emergency medical service workers.

Alexandros G. SfakianakisστοSwallowing and Swallowing Disorders (Dysphagia)Πριν από 37 δευτερόλεπτα
[image: http:--highwire.stanford.edu-icons-exter] Related Articles *World Trade Center-related physical and mental health burden among New York City Fire Department emergency medical service workers.* Occup Environ Med. 2016 Jan;73(1):13-20 Authors: Yip J, Zeig-Owens R, Webber MP, Kablanian A, Hall CB, Vossbrinck M, Liu X, Weakley J, Schwartz T, Kelly KJ, Prezant DJ Abstract OBJECTIVES: To describe the health burden among Fire Department of the City of New York (FDNY) emergency medical service (EMS) workers and examine its association with work at the World Trade Center (WTC) disas... περισσότερα »

Congenital vascular rings: a clinical challenge for the pediatrician.

Alexandros G. SfakianakisστοSwallowing and Swallowing Disorders (Dysphagia)Πριν από 37 δευτερόλεπτα
[image: http:--media.wiley.com-assets-7315-19-Wi] Related Articles *Congenital vascular rings: a clinical challenge for the pediatrician.* Pediatr Pulmonol. 2015 May;50(5):511-24 Authors: Licari A, Manca E, Rispoli GA, Mannarino S, Pelizzo G, Marseglia GL Abstract Vascular rings are congenital anomalies that lead to variable degrees of respiratory problems or feeding difficulties by forming a complete or partial ring compressing the trachea, the bronchi, and the esophagus. The clinical diagnosis of vascular rings is often challenging for the pediatrician because the clinical manife... περισσότερα »

Obstructive sleep apnea syndrome and gastroesophageal reflux disease: the importance of obesity and gender.

Alexandros G. SfakianakisστοSwallowing and Swallowing Disorders (Dysphagia)Πριν από 37 δευτερόλεπτα
[image: http:--production.springer.de-OnlineReso] Related Articles *Obstructive sleep apnea syndrome and gastroesophageal reflux disease: the importance of obesity and gender.* Sleep Breath. 2015 May;19(2):585-92 Authors: Basoglu OK, Vardar R, Tasbakan MS, Ucar ZZ, Ayik S, Kose T, Bor S Abstract BACKGROUND: It is claimed that gastroesophageal reflux disease (GERD) increases in patients with obstructive sleep apnea syndrome (OSAS). We aimed to evaluate the prevalence of GERD in patients with OSAS and primary snoring and identify OSAS-related risk factors associated with GERD. METHOD... περισσότερα »

Effect of dysphagia rehabilitation on oral intake in elderly patients with aspiration pneumonia.

Alexandros G. SfakianakisστοSwallowing and Swallowing Disorders (Dysphagia)Πριν από 37 δευτερόλεπτα
[image: http:--media.wiley.com-assets-7315-19-Wi] Related Articles *Effect of dysphagia rehabilitation on oral intake in elderly patients with aspiration pneumonia.* Geriatr Gerontol Int. 2015 Jun;15(6):694-9 Authors: Momosaki R, Yasunaga H, Matsui H, Horiguchi H, Fushimi K, Abo M Abstract AIM: To clarify the effects of dysphagia rehabilitation on oral intake after aspiration pneumonia in older adults. METHODS: The present retrospective observational study used data from the Japanese Diagnosis Procedure Combination inpatient database. We identified patients who were admitted to acu... περισσότερα »

An unusual case of progressive dysphagia.

Alexandros G. SfakianakisστοSwallowing and Swallowing Disorders (Dysphagia)Πριν από 37 δευτερόλεπτα
[image: http:--linkinghub.elsevier.com-ihub-imag] Related Articles *An unusual case of progressive dysphagia.* Gastroenterology. 2015 Nov;149(6):1337-8 Authors: Choe JW, Jung SW, Lee SW PMID: 26409240 [PubMed - indexed for MEDLINE] from Swallowing and Swallowing Disorders (Dysphagia) via xlomafota13 on Inoreader http://ift.tt/1RIbnIx via IFTTT

Increased risk of functional gastrointestinal sequelae after Clostridium difficile infection among active duty United States military personnel (1998-2010).

Alexandros G. SfakianakisστοSwallowing and Swallowing Disorders (Dysphagia)Πριν από 37 δευτερόλεπτα
[image: http:--linkinghub.elsevier.com-ihub-imag] Related Articles *Increased risk of functional gastrointestinal sequelae after Clostridium difficile infection among active duty United States military personnel (1998-2010).* Gastroenterology. 2015 Nov;149(6):1408-14 Authors: Gutiérrez RL, Riddle MS, Porter CK Abstract BACKGROUND &amp; AIMS: Some acute enteric infections are associated with the development of functional gastrointestinal disorders, most commonly irritable bowel syndrome but also other functional and organic gastrointestinal sequelae. Clostridium difficile infection ha... περισσότερα »

Thyrocricotracheal separation with bilateral recurrent laryngeal nerve transsection: report of a survivor.

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngolgy NewsΠριν από 47 δευτερόλεπτα
[image: http:--linkinghub.elsevier.com-ihub-imag] Related Articles *Thyrocricotracheal separation with bilateral recurrent laryngeal nerve transsection: report of a survivor.* Am J Emerg Med. 2015 Dec;33(12):1849.e1-3 Authors: Ahn D, Choi JH, Sohn JH Abstract Thyrocricotracheal separation is an extremely fatal injury that has not been reported in the literature. Although timely and proper management of this injury is paramount to preserve the patient's life, airway, and voice, its rarity has resulted in a lack of consensus regarding the best management option. We report a case of... περισσότερα »

Laser arytenoidectomy and posterior cordotomy in a patient with bilateral vocal cord paralysis due to multiple system atrophy.

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngolgy NewsΠριν από 47 δευτερόλεπτα
[image: http:--highwire.stanford.edu-icons-exter] Related Articles *Laser arytenoidectomy and posterior cordotomy in a patient with bilateral vocal cord paralysis due to multiple system atrophy.* BMJ Case Rep. 2015;2015 Authors: Mahmud A, Strens LH, Tedla M Abstract Bilateral vocal cord paralysis leading to stridor is a known but rare complication of Parkinson's disease (PD) and a recognised complication of multiple system atrophy (MSA). Tracheostomy is a commonly offered treatment, leading to substantial adaptations and lifestyle changes for the patient. Patients can struggle to... περισσότερα »

The Effect of Microphone Placement on Interaural Level Differences and Sound Localization Across the Horizontal Plane in Bilateral Cochlear Implant Users.

Alexandros G. SfakianakisστοΑκοή και ΙσορροπίαΠριν από 47 δευτερόλεπτα
The effect of microphone placement on the interaural level differences available to bilateral cochlear implant users, and subsequent effects on horizontal-plane sound localization were investigated. Presently, microphones are most commonly placed behind the ear in adults, and sometimes on the shoulders in children. While efforts to position microphones in the ear exist, the impact of such placements on sound localization in bilateral cochlear implant users is not well understood. Sound localization was tested for these three microphone placements using virtual acoustic stimuli creat... περισσότερα »

The Effect of Microphone Placement on Interaural Level Differences and Sound Localization Across the Horizontal Plane in Bilateral Cochlear Implant Users.

Alexandros G. SfakianakisστοΑκοή και ΙσορροπίαΠριν από 47 δευτερόλεπτα
The effect of microphone placement on the interaural level differences available to bilateral cochlear implant users, and subsequent effects on horizontal-plane sound localization were investigated. Presently, microphones are most commonly placed behind the ear in adults, and sometimes on the shoulders in children. While efforts to position microphones in the ear exist, the impact of such placements on sound localization in bilateral cochlear implant users is not well understood. Sound localization was tested for these three microphone placements using virtual acoustic stimuli creat... περισσότερα »

Phenotypic insights into ADCY5-associated disease

orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 54 δευτερόλεπτα
ABSTRACT Background Adenylyl cyclase 5 (ADCY5) mutations is associated with heterogenous syndromes: familial dyskinesia and facial myokymia; paroxysmal chorea and dystonia; autosomal-dominant chorea and dystonia; and benign hereditary chorea. We provide detailed clinical data on 7 patients from six new kindreds with mutations in the ADCY5 gene, in order to expand and define the phenotypic… Continue reading Phenotypic insights into ADCY5-associated disease

The emerging role of transcranial magnetic resonance imaging–guided focused ultrasound in functional neuros urgery

orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 54 δευτερόλεπτα
ABSTRACT To review the emerging role of transcranial MR-guided focused ultrasound as a treatment and research modality for functional neurological disorders, we summarize recent clinical and preclinical studies. Clinical trials have investigated the safety and efficacy of thermal lesions created by transcranial, high-intensity focused ultrasound. Preclinical work has additionally investigated the ability to disrupt the… Continue reading The emerging role of transcranial magnetic resonance imaging–guided focused ultrasound in functional neuros urgery

Tics as a model of over-learned behavior—imitation and inhibition of facial tics

orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 54 δευτερόλεπτα
ABSTRACT Background Tics are the defining feature in Tourette syndrome and can be triggered by watching tics or single voluntary movements. This automatic imitation of movements referred to as “echopraxia” has been ascribed to a failure in top-down inhibition of imitative response tendencies. Alternatively, it could be interpreted in the context of automatic overlearned behavior.… Continue reading Tics as a model of over-learned behavior—imitation and inhibition of facial tics

Cortical phosphorylated α-Synuclein levels correlate with brain wave spectra in Parkinson’s disease

orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 54 δευτερόλεπτα
ABSTRACT Introduction Quantitative EEG features have been identified as surrogates and predictors of cognitive decline/dementia, a common feature of progressive PD. The biochemical correlates for altered quantitative EEG features are unknown. Our primary objective was to test the hypothesis that quantitative EEG measures correlate with cortical levels of phosphorylated α-synuclein, a modified form of the… Continue reading Cortical phosphorylated α-Synuclein levels correlate with brain wave spectra in Parkinson’s disease

Cerebellar dysfunction in essential tremor

orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 54 δευτερόλεπτα
ABSTRACT Objectives Few neurophysiological studies have investigated cerebellar function in patients with essential tremor, even though the cerebellum may contribute to tremor generation. Here, we studied cerebellar function in patients with essential tremor using 2 physiological methods. Methods Participants were 20 patients with essential tremor and 30 age-matched healthy volunteers, and the results were compared… Continue reading Cerebellar dysfunction in essential tremor

One Year Effects of a Workplace Integrated Care Intervention for Workers with Rheumatoid Arthritis: Results of a Randomized Controlled Trial

orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 54 δευτερόλεπτα
Abstract Purpose To evaluate the effectiveness of a workplace integrated care intervention on at-work productivity loss in workers with rheumatoid arthritis (RA) compared to usual care. Methods In this randomized controlled trial, 150 workers with RA were randomized into either the intervention or control group. The intervention group received an integrated care and participatory workplace… Continue reading One Year Effects of a Workplace Integrated Care Intervention for Workers with Rheumatoid Arthritis: Results of a Randomized Controlled Trial

Was metakognitives Training bei Schizophrenie bringt

orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 54 δευτερόλεπτα
Wahn reduzieren Das für schizophrene Patienten entwickelte MKT zielt darauf ab, die kognitiven Verzerrungen, die mit Wahnvorstellungen und Problemen in der Perspektivübernahme sowie in der sozialen Wahrnehmung assoziiert sind, zu verringern, bevor die Hauptsymptome der Schizophrenie bearbeitet werden. Wirkt es? from #Medicine-Sfakianakis via simeraentaxei on Inoreader http://ift.tt/1VDznxP via IFTTT

IJMS, Vol. 17, Pages 516: Intervention of Grape Seed Proanthocyanidin Extract on the Subchronic Immune Injury in Mice Induced by Aflatoxin B1

orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 54 δευτερόλεπτα
The aim was to investigate the prevention of grape seed proanthocyanidin extract (GSPE) on the subchronic immune injury induced by aflatoxin B1 (AFB1) and the possible ameliorating effect of GSPE in mice. The subchronic AFB1-induced immune injury mice model was set up with the continuous administration of 100 μg/kg body weight (BW) AFB1 for six… Continue reading IJMS, Vol. 17, Pages 516: Intervention of Grape Seed Proanthocyanidin Extract on the Subchronic Immune Injury in Mice Induced by Aflatoxin B1

IJMS, Vol. 17, Pages 534: Pancreatic Transdifferentiation and Glucose-Regulated Production of Human Insulin in the H4IIE Rat Liver Cell Line

orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 54 δευτερόλεπτα
Due to the limitations of current treatment regimes, gene therapy is a promising strategy being explored to correct blood glucose concentrations in diabetic patients. In the current study, we used a retroviral vector to deliver either the human insulin gene alone, the rat NeuroD1 gene alone, or the human insulin gene and rat NeuroD1 genes… Continue reading IJMS, Vol. 17, Pages 534: Pancreatic Transdifferentiation and Glucose-Regulated Production of Human Insulin in the H4IIE Rat Liver Cell Line

IJMS, Vol. 17, Pages 529: Anti-Inflammatory and Cytoprotective Effects of TMC-256C1 from Marine-Derived Fungus Aspergillus sp. SF-6354 via up-Regulation of Heme Oxygenase-1 in Murine Hippocampal and Microglial Cell Lines

orlsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.AlexandrosΠριν από 54 δευτερόλεπτα
In the course of searching for bioactive secondary metabolites from marine fungi, TMC-256C1 was isolated from an ethyl acetate extract of the marine-derived fungus Aspergillus sp. SF6354. TMC-256C1 displayed anti-neuroinflammatory effect in BV2 microglial cells induced by lipopolysaccharides (LPS) as well as neuroprotective effect against glutamate-stimulated neurotoxicity in mouse hippocampal HT22 cells. TMC-256C1 was shown… Continue reading IJMS, Vol. 17, Pages 529: Anti-Inflammatory and Cytoprotective Effects of TMC-256C1 from Marine-Derived Fungus Aspergillus sp. SF-6354 via up-... περισσότερα »

Erratum to: Occult pneumothorax in blunt trauma: is there a need for tube thoracostomy?

Alexandros G. SfakianakisστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 55 δευτερόλεπτα
from Emergency Medicine via xlomafota13 on Inoreader http://ift.tt/1SUu1fu via IFTTT

miR-21 contributes to renal protection by targeting prolyl hydroxylase domain protein 2 in delayed ischemic preconditioning

Alexandros G. SfakianakisστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 55 δευτερόλεπτα
Nephrology from Emergency Medicine via ola Kala on Inoreader http://ift.tt/1MjuqJd via IFTTT

Does bedside sonography effectively identify nasogastric tube placements in pediatric critical care patients?

Alexandros G. SfakianakisστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 55 δευτερόλεπτα
Nutrition in Clinical Practice from Emergency Medicine via ola Kala on Inoreader http://ift.tt/22hj1eB via IFTTT

Inferior accessory ossicle of the anterior arch of the atlas in a trauma patient

Alexandros G. SfakianakisστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 55 δευτερόλεπτα
The Spine Journal from Emergency Medicine via ola Kala on Inoreader http://ift.tt/1MjuoRC via IFTTT

Periprosthetic atypical femoral fractures in patients on long-term bisphosphonates: A multicenter retrospective review

Alexandros G. SfakianakisστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 55 δευτερόλεπτα
Journal of Orthopaedic Trauma from Emergency Medicine via ola Kala on Inoreader http://ift.tt/22hj3mN via IFTTT

Injuries caused by fragmenting rifle ammunition

Alexandros G. SfakianakisστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 55 δευτερόλεπτα
Injury from Emergency Medicine via ola Kala on Inoreader http://ift.tt/1MjuoRu via IFTTT

Tailored ultrasound learning for acute care surgeons: a review of the MUSEC (Modular UltraSound ESTES Course) project

Alexandros G. SfakianakisστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 55 δευτερόλεπτα
European Journal of Trauma and Emergency Surgery from Emergency Medicine via ola Kala on Inoreader http://ift.tt/22hj1ew via IFTTT

Success rates for notification of enrollment in exception from informed consent clinical trials

Alexandros G. SfakianakisστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 55 δευτερόλεπτα
Academic Emergency Medicine from Emergency Medicine via ola Kala on Inoreader http://ift.tt/1MjuqJ3 via IFTTT

Airway disorders of the fetus and neonate: An overview

Alexandros G. SfakianakisστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 55 δευτερόλεπτα
Seminars in Fetal and Neonatal Medicine from Emergency Medicine via ola Kala on Inoreader http://ift.tt/22hj1es via IFTTT

High incidence of undiagnosed cervical myelopathy in patients with hip fracture compared with controls

Alexandros G. SfakianakisστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 55 δευτερόλεπτα
Journal of Orthopaedic Trauma from Emergency Medicine via ola Kala on Inoreader http://ift.tt/1MjuoRn via IFTTT

Smartwatches as chest compression feedback devices: A feasibility study

Alexandros G. SfakianakisστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 55 δευτερόλεπτα
Resuscitation from Emergency Medicine via ola Kala on Inoreader http://ift.tt/22hj3mD via IFTTT

Trauma patient readmission: Why do they come back for more?

Alexandros G. SfakianakisστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 55 δευτερόλεπτα
The Journal of Emergency Medicine from Emergency Medicine via ola Kala on Inoreader http://ift.tt/1MjuqsJ via IFTTT

Tranexamic acid use in United States children's hospitals

Alexandros G. SfakianakisστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 55 δευτερόλεπτα
The Journal of Emergency Medicine from Emergency Medicine via ola Kala on Inoreader http://ift.tt/22hj0Y7 via IFTTT

Trauma centers with higher rates of angiography have a lesser incidence of splenectomy in the management of blunt splenic injury

Alexandros G. SfakianakisστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 55 δευτερόλεπτα
The Journal of Emergency Medicine from Emergency Medicine via ola Kala on Inoreader http://ift.tt/1MjuqsH via IFTTT

Early management in children with burns: Cooling, wound care and pain management

Alexandros G. SfakianakisστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 55 δευτερόλεπτα
Burns from Emergency Medicine via ola Kala on Inoreader http://ift.tt/22hj36j via IFTTT

Medical Emergency Team: How do we play when we stay? Characterization of MET actions at the scene

Alexandros G. SfakianakisστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 55 δευτερόλεπτα
Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine from Emergency Medicine via ola Kala on Inoreader http://ift.tt/1MjuqsB via IFTTT

Air pollution exposure during pregnancy and fetal markers of metabolic function: The MIREC Study

Alexandros G. SfakianakisστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 55 δευτερόλεπτα
American Journal of Epidemiology from Emergency Medicine via ola Kala on Inoreader http://ift.tt/22hj36d via IFTTT

The forensic lens: bringing elder neglect into focus in the emergency department

Alexandros G. SfakianakisστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 55 δευτερόλεπτα
Annals of Emergency Medicine from Emergency Medicine via ola Kala on Inoreader http://ift.tt/1MjuokC via IFTTT

Four-factor prothrombin complex concentrate–associated hypotension

Alexandros G. SfakianakisστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 55 δευτερόλεπτα
The American Journal of Emergency Medicine from Emergency Medicine via ola Kala on Inoreader http://ift.tt/22hj36b via IFTTT

Australian insurance costs of jockeys injured in a race-day fall

Alexandros G. SfakianakisστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 55 δευτερόλεπτα
Occupational Medicine from Emergency Medicine via ola Kala on Inoreader http://ift.tt/1Mjuoky via IFTTT

Can Community Social Cohesion Prevent Posttraumatic Stress Disorder in the Aftermath of a Disaster? A Natural Experiment From the 2011 Tohoku Earthquake and Tsunami

Alexandros G. SfakianakisστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 55 δευτερόλεπτα
American Journal of Epidemiology from Emergency Medicine via ola Kala on Inoreader http://ift.tt/22hj0Y1 via IFTTT

miR-21 contributes to renal protection by targeting prolyl hydroxylase domain protein 2 in delayed ischemic preconditioning

Alexandros G. SfakianakisστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 55 δευτερόλεπτα
Nephrology from Emergency Medicine via xlomafota13 on Inoreader http://ift.tt/1MjuqJd via IFTTT

Does bedside sonography effectively identify nasogastric tube placements in pediatric critical care patients?

Alexandros G. SfakianakisστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 55 δευτερόλεπτα
Nutrition in Clinical Practice from Emergency Medicine via xlomafota13 on Inoreader http://ift.tt/22hj1eB via IFTTT

Inferior accessory ossicle of the anterior arch of the atlas in a trauma patient

Alexandros G. SfakianakisστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 55 δευτερόλεπτα
The Spine Journal from Emergency Medicine via xlomafota13 on Inoreader http://ift.tt/1MjuoRC via IFTTT

Periprosthetic atypical femoral fractures in patients on long-term bisphosphonates: A multicenter retrospective review

Alexandros G. SfakianakisστοEmergency Medicine by Alexandros G. SfakianakisΠριν από 55 δευτερόλεπτα
Journal of Orthopaedic Trauma from Emergency Medicine via xlomafota13 on Inoreader http://ift.tt/22hj3mN via IFTTT

Empowering the family during the first months after identification of permanent hearing impairment in children.

Αλέξανδρος ΣφακιανάκηςστοAudiology by Alexandros G. SfakianakisΠριν από 56 δευτερόλεπτα
*Empowering the family during the first months after identification of permanent hearing impairment in children.* Acta Otorhinolaryngol Ital. 2016 Feb;36(1):64-70 Authors: Ciciriello E, Bolzonello P, Marchi R, Falzone C, Muzzi E, Orzan E Abstract The latest international guidelines highlight the importance of involving the family in the diagnositic and rehabilitation process of children affected by permanent hearing impairment. This emphasises how meaningful this approach is for the development of the deaf child. So far, there is very little evidence about this approach in Italy, ... περισσότερα »

Achieving early functional auditory access in paediatric cochlear implantation.

Αλέξανδρος ΣφακιανάκηςστοAudiology by Alexandros G. SfakianakisΠριν από 56 δευτερόλεπτα
*Achieving early functional auditory access in paediatric cochlear implantation.* Acta Otorhinolaryngol Ital. 2016 Feb;36(1):45-50 Authors: Orzan E, Muzzi E, Marchi R, Falzone C, Battelino S, Ciciriello E Abstract Cochlear implantation (CI) is a viable option for providing access to auditory stimulation in severe-to-profound hearing loss/impairment of cochlear origin. It has been demonstrated that CI is safe and effective for deaf children. Younger age at activation after CI is linked with better outcomes. It is important to study variables and issues that can interfere with an e... περισσότερα »

Childhood hearing surveillance activity in Italy: preliminary recommendations.

Αλέξανδρος ΣφακιανάκηςστοAudiology by Alexandros G. SfakianakisΠριν από 56 δευτερόλεπτα
*Childhood hearing surveillance activity in Italy: preliminary recommendations.* Acta Otorhinolaryngol Ital. 2016 Feb;36(1):15-20 Authors: Orzan E, Ruta F, Bolzonello P, Marchi R, Ceschin F, Ciciriello E Abstract Following the positive outcomes of the newborn hearing screening programmes already underway in several Italian regions, it is now necessary to address the identification of childhood hearing impairments that missed the neonatal screening programme or have delayed onset. Within the framework of the Ministry of Health project CCM 2013 "Preventing Communication Disorders: ...περισσότερα »

Hearing Profile in Patients with Dilated and Hypertrophic Cardiomyopathies.

Αλέξανδρος ΣφακιανάκηςστοAudiology by Alexandros G. SfakianakisΠριν από 56 δευτερόλεπτα
*Hearing Profile in Patients with Dilated and Hypertrophic Cardiomyopathies.* Electron Physician. 2016 Feb;8(2):2030-8 Authors: El-Zarea GA, Hassan YE, Mahmoud AM Abstract INTRODUCTION: Cardiomyopathy may cause disruptions in the micro-vascular system of the stria vascularis in the cochlea, and, subsequently, may result in cochlear degeneration. Degeneration in the stria vascularis affects the physical and chemical processes in the organ of Corti, thereby causing a possible hearing impairment. The objective of this study was to assess the hearing profiles of patients with dilated...περισσότερα »

The Effect of Microphone Placement on Interaural Level Differences and Sound Localization Across the Horizontal Plane in Bilateral Cochlear Implant Users.

Αλέξανδρος ΣφακιανάκηςστοAudiology by Alexandros G. SfakianakisΠριν από 56 δευτερόλεπτα
The effect of microphone placement on the interaural level differences available to bilateral cochlear implant users, and subsequent effects on horizontal-plane sound localization were investigated. Presently, microphones are most commonly placed behind the ear in adults, and sometimes on the shoulders in children. While efforts to position microphones in the ear exist, the impact of such placements on sound localization in bilateral cochlear implant users is not well understood. Sound localization was tested for these three microphone placements using virtual acoustic stimuli creat... περισσότερα »

The Effect of Microphone Placement on Interaural Level Differences and Sound Localization Across the Horizontal Plane in Bilateral Cochlear Implant Users.

Αλέξανδρος ΣφακιανάκηςστοAudiology by Alexandros G. SfakianakisΠριν από 56 δευτερόλεπτα
The effect of microphone placement on the interaural level differences available to bilateral cochlear implant users, and subsequent effects on horizontal-plane sound localization were investigated. Presently, microphones are most commonly placed behind the ear in adults, and sometimes on the shoulders in children. While efforts to position microphones in the ear exist, the impact of such placements on sound localization in bilateral cochlear implant users is not well understood. Sound localization was tested for these three microphone placements using virtual acoustic stimuli creat... περισσότερα »

The Effect of Microphone Placement on Interaural Level Differences and Sound Localization Across the Horizontal Plane in Bilateral Cochlear Implant Users.

Αλέξανδρος ΣφακιανάκηςστοAudiology by Alexandros G. SfakianakisΠριν από 56 δευτερόλεπτα
The effect of microphone placement on the interaural level differences available to bilateral cochlear implant users, and subsequent effects on horizontal-plane sound localization were investigated. Presently, microphones are most commonly placed behind the ear in adults, and sometimes on the shoulders in children. While efforts to position microphones in the ear exist, the impact of such placements on sound localization in bilateral cochlear implant users is not well understood. Sound localization was tested for these three microphone placements using virtual acoustic stimuli creat... περισσότερα »

Anti-VEGF treatment for myopic choroid neovascularization: from molecular characterization to update on clinical application.

Alexandros G. SfakianakisστοHead and NeckΠριν από 1 ώρα
[image: http:--http://ift.tt/1Fkw4zC] Related Articles *Anti-VEGF treatment for myopic choroid neovascularization: from molecular characterization to update on clinical application.* Drug Des Devel Ther. 2015;9:3413-21 Authors: Zhang Y, Han Q, Ru Y, Bo Q, Wei RH Abstract Choroidal neovascularization (CNV) secondary to pathologic myopia has a very high incidence in global, especially in Asian, populations. It is a common cause of irreversible central vision loss, and severely affects the quality of life in the patients with pathologic myopia. The traditional therapeutic modalities... περισσότερα »

Obstructive sleep apnea syndrome and gastroesophageal reflux disease: the importance of obesity and gender.

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 1 ώρα
[image: http:--production.springer.de-OnlineReso] Related Articles *Obstructive sleep apnea syndrome and gastroesophageal reflux disease: the importance of obesity and gender.* Sleep Breath. 2015 May;19(2):585-92 Authors: Basoglu OK, Vardar R, Tasbakan MS, Ucar ZZ, Ayik S, Kose T, Bor S Abstract BACKGROUND: It is claimed that gastroesophageal reflux disease (GERD) increases in patients with obstructive sleep apnea syndrome (OSAS). We aimed to evaluate the prevalence of GERD in patients with OSAS and primary snoring and identify OSAS-related risk factors associated with GERD. METHO... περισσότερα »

Effect of dysphagia rehabilitation on oral intake in elderly patients with aspiration pneumonia.

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngology by Alexandros G.SfakianakisΠριν από 1 ώρα
[image: http:--media.wiley.com-assets-7315-19-Wi] Related Articles *Effect of dysphagia rehabilitation on oral intake in elderly patients with aspiration pneumonia.* Geriatr Gerontol Int. 2015 Jun;15(6):694-9 Authors: Momosaki R, Yasunaga H, Matsui H, Horiguchi H, Fushimi K, Abo M Abstract AIM: To clarify the effects of dysphagia rehabilitation on oral intake after aspiration pneumonia in older adults. METHODS: The present retrospective observational study used data from the Japanese Diagnosis Procedure Combination inpatient database. We identified patients who were admitted to ac... περισσότερα »

Retrosigmoid Craniotomy for Auditory Brainstem Implantation in Adult Patients with Neurofibromatosis Type 2.

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngolgy NewsΠριν από 1 ώρα
*Retrosigmoid Craniotomy for Auditory Brainstem Implantation in Adult Patients with Neurofibromatosis Type 2.* J Neurol Surg B Skull Base. 2015 Dec;76(6):440-50 Authors: Puram SV, Herrmann B, Barker FG, Lee DJ Abstract Objective To report our technique and experience using a retrosigmoid craniotomy approach for auditory brainstem implantation (ABI) placement in adult neurofibromatosis type 2 (NF2) patients. Design Retrospective case series. Setting Single-center study, Boston, Massachusetts, United States. Participants All NF2 patients who underwent evaluation at Massachusetts Eye...περισσότερα »

Ehrlichia Meningitis Mimicking Aneurysmal Subarachnoid Hemorrhage: A Case Study for Medical Decision-Making Heuristics.

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngolgy NewsΠριν από 1 ώρα
*Ehrlichia Meningitis Mimicking Aneurysmal Subarachnoid Hemorrhage: A Case Study for Medical Decision-Making Heuristics.* Neurohospitalist. 2016 Apr;6(2):76-9 Authors: Dredla B, Freeman WD Abstract Thunderclap headache is a sudden and severe headache that can occur after an aneurysmal subarachnoid hemorrhage (SAH). Subarachnoid hemorrhage is a medical emergency that requires prompt attention and hospitalization. Patients with thunderclap headache often undergo a noncontrast head computed tomography (CT) scan to ascertain SAH bleeding and, if the scan is negative, then undergo a l... περισσότερα »

Utility of nonpenetrating titanium clips for dural closure during spinal surgery to prevent postoperative cerebrospinal fluid leakage.

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngolgy NewsΠριν από 1 ώρα
Related Articles *Utility of nonpenetrating titanium clips for dural closure during spinal surgery to prevent postoperative cerebrospinal fluid leakage.* J Neurosurg Spine. 2015 Dec;23(6):812-9 Authors: Ito K, Aoyama T, Horiuchi T, Hongo K Abstract OBJECT: The nonpenetrating titanium clip has been successfully used in peripheral arterial bypass surgery. The purpose of this study was to evaluate the leakage pressures and patterns of nonpenetrating titanium clips using a simple model that mimicked spinal surgery. In addition, the authors describe their surgical experience with thes... περισσότερα »

Adenosine-mediated immunosuppression in patients with squamous cell carcinoma of the head and neck.

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngolgy NewsΠριν από 1 ώρα
*Adenosine-mediated immunosuppression in patients with squamous cell carcinoma of the head and neck.* HNO. 2016 Apr 6; Authors: Mandapathil M Abstract This review article describes the potential role of ectonucleotidase activity, adenosine metabolism, and the adenosinergic signaling pathway in the suppression of the host immune system in patients with head and neck cancer. Identifying such mechanisms leads to a better understanding of immunosuppressive mechanisms in this patient population. Further, potential targets for immunotherapy in an adjuvant approach to treating squamous ...περισσότερα »

Association of BMI-1 and p16 as prognostic factors for head and neck carcinomas.

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngolgy NewsΠριν από 1 ώρα
*Association of BMI-1 and p16 as prognostic factors for head and neck carcinomas.* Acta Otolaryngol. 2016 May;136(5):501-5 Authors: Lundberg M, Renkonen S, Haglund C, Mattila PS, Leivo I, Hagström J, Mäkitie AA Abstract Conclusions BMI-1 is an upstream repressor of tumor suppressor p16 and their inverse expression patterns have been linked with patient survival in OPSCC. In this material only p16 remained a relevant prognostic marker in OPSCC. Objectives HNSCC tumors carry variable phenotypes and clinical outcomes depending on their anatomical location. In OPSCC, expression of t... περισσότερα »

Th17 expression and IL-17 levels in laryngeal squamous cell carcinoma patients.

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngolgy NewsΠριν από 1 ώρα
*Th17 expression and IL-17 levels in laryngeal squamous cell carcinoma patients.* Acta Otolaryngol. 2016 May;136(5):484-90 Authors: Li FJ, Cai ZJ, Yang F, Zhang SD, Chen M Abstract Conclusion The Th17 cell frequency in peripheral blood and levels of IL-17 showed significant differences between patients with laryngeal squamous cell carcinoma and those with vocal cords polyps. Serum levels of IL-17 were correlated with laryngocarcinoma staging. Objectives To investigate associations among the frequency of Th17 cells, levels of IL-17, and laryngeal squamous cell carcinoma. Method Ei... περισσότερα »

Anatomic measurements of the posterior tympanum related to the round window vibroplasty in congenital aural atresia and stenosis patients.

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngolgy NewsΠριν από 1 ώρα
*Anatomic measurements of the posterior tympanum related to the round window vibroplasty in congenital aural atresia and stenosis patients.* Acta Otolaryngol. 2016 May;136(5):470-4 Authors: Chen K, Yin D, Lyu H, Yang L, Zhang T, Dai P Abstract Conclusions With the aggravation of the external auditory canal malformation, the size of extra-niche fossa became smaller, providing concrete data and valuable information for the better design, selecting and safer implantation of the transducer in the area of round window niche. Three-dimensional measurements and assessments before surgery...περισσότερα »

Pregnancy is not a risk factor for idiopathic sudden sensorineural hearing loss: A nationwide population-based study.

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngolgy NewsΠριν από 1 ώρα
*Pregnancy is not a risk factor for idiopathic sudden sensorineural hearing loss: A nationwide population-based study.* Acta Otolaryngol. 2016 May;136(5):446-50 Authors: Yen TT, Lin CH, Shiao JY, Liang KL Abstract Conclusion Sudden sensorineural hearing loss (SSNHL) in pregnancy is rare. It usually occurs in the third trimester. SSNHL in pregnancy does not increase risks during delivery or subsequent stroke. Objectives This study aimed to investigate the incidence and to determine the factors associated with SSNHL in pregnancy. Method Data were retrieved from Taiwan's National He...περισσότερα »

Treatment of idiopathic rhinitis with kinetic oscillations - a multi-centre randomized controlled study.

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngolgy NewsΠριν από 1 ώρα
*Treatment of idiopathic rhinitis with kinetic oscillations - a multi-centre randomized controlled study.* Acta Otolaryngol. 2016 Apr 7;:1-8 Authors: Ehnhage A, Johnsson PS, Ahlström-Emanuelsson C, Andersson M, Knutsson J, Lien J, Norlander T, Olsson P, Friis-Liby JE, Holmström M Abstract CONCLUSIONS: The potential effects of KOS are still uncertain regarding the most effective air pressure to be used as well as the physiological effects on the nasal mucosa. The results of the study do not support a convincing treatment effect by KOS on IR. OBJECTIVES: Idiopathic rhinitis (IR) is ... περισσότερα »

Transzygomatic Approach to Skull Base: History, Evolution, and Possibility of a Simple Modification.

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngolgy NewsΠριν από 1 ώρα
*Transzygomatic Approach to Skull Base: History, Evolution, and Possibility of a Simple Modification.* J Craniofac Surg. 2016 Apr 5; Authors: Badwal JS Abstract The surgical approaches to anterior, middle, and lateral skull base have evolved drastically, transcending from an era of oblivion to well-defined and systematically executed, state-of-the-art, refined surgery. The transzygomatic approach, which was developed to access the nasopharynx, has been applied to versatile locations of skull base pathology, with continuous evolution and modification of the osteotomies and skin fl... περισσότερα »

Retrosigmoid Craniotomy for Auditory Brainstem Implantation in Adult Patients with Neurofibromatosis Type 2.

Αλέξανδρος ΣφακιανάκηςστοOtoRhinoLaryngolgy NewsΠριν από 1 ώρα
*Retrosigmoid Craniotomy for Auditory Brainstem Implantation in Adult Patients with Neurofibromatosis Type 2.* J Neurol Surg B Skull Base. 2015 Dec;76(6):440-50 Authors: Puram SV, Herrmann B, Barker FG, Lee DJ Abstract Objective To report our technique and experience using a retrosigmoid craniotomy approach for auditory brainstem implantation (ABI) placement in adult neurofibromatosis type 2 (NF2) patients. Design Retrospective case series. Setting Single-center study, Boston, Massachusetts, United States. Participants All NF2 patients who underwent evaluation at Massachusetts Eye...περισσότερα »

Endonasal Skull Base Tumor Removal Using Concentric Tube Continuum Robots: A Phantom Study.

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*Endonasal Skull Base Tumor Removal Using Concentric Tube Continuum Robots: A Phantom Study.* J Neurol Surg B Skull Base. 2015 Mar;76(2):145-9 Authors: Swaney PJ, Gilbert HB, Webster RJ, Russell PT, Weaver KD Abstract Objectives The purpose of this study is to experimentally evaluate the use of concentric tube continuum robots in endonasal skull base tumor removal. This new type of surgical robot offers many advantages over existing straight and rigid surgical tools including added dexterity, the ability to scale movements, and the ability to rotate the end effector while leaving ...περισσότερα »

Simultaneous Transventricular-Orbitocranial Resection of Large Suprasellar Craniopharyngioma as Inspired by Jackson's Maneuver from 1863.

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*Simultaneous Transventricular-Orbitocranial Resection of Large Suprasellar Craniopharyngioma as Inspired by Jackson's Maneuver from 1863.* Cureus. 2016;8(3):e517 Authors: Jean WC, Syed HR, Felbaum D, Ryan JE, Anaizi A Abstract Traditional skull base techniques utilizing the microscope have allowed surgeons improved safe access to deep-seated lesions. More recent technical advances with the endoscope have allowed improved visibility and access to these previously difficult-to-reach regions. Most current literature emphasizes one technique over the other. We present a unique hybrid...περισσότερα »

Reply to comments on: Is endoscopic ear surgery an alternative to the modified Bondy technique for limited epitympanic cholesteatoma?

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*Reply to comments on: Is endoscopic ear surgery an alternative to the modified Bondy technique for limited epitympanic cholesteatoma?* Eur Arch Otorhinolaryngol. 2016 Apr 6; Authors: Prasad SC, Sanna M PMID: 27052548 [PubMed - as supplied by publisher] from #ENT-PubMed via ola Kala on Inoreader http://ift.tt/1Ndboii via IFTTT

A neurosurgical simulation of skull base tumors using a 3D printed rapid prototyping model containing mesh structures.

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*A neurosurgical simulation of skull base tumors using a 3D printed rapid prototyping model containing mesh structures.* Acta Neurochir (Wien). 2016 Apr 6; Authors: Kondo K, Harada N, Masuda H, Sugo N, Terazono S, Okonogi S, Sakaeyama Y, Fuchinoue Y, Ando S, Fukushima D, Nomoto J, Nemoto M Abstract BACKGROUND: Deep regions are not visible in three-dimensional (3D) printed rapid prototyping (RP) models prepared from opaque materials, which is not the case with translucent images. The objectives of this study were to develop an RP model in which a skull base tumor was simulated usin... περισσότερα »