OtoRhinoLaryngology,New Articles,February 16th,2016
OtoRhinoLaryngology - Alexandros G. Sfakianakis - Helicobacter pylori positive or negative children with resistant otitis media with effusionAlexandros G. Sfakianakis, 2016-02-16 09:23:28 AM Outcome evaluation of clarithromycin, metronidazole and lansoprazole regimens in Helicobacter pylori positive or negative children with resistant otitis media with effusion: Letter S S Bakshi, The Journal of Laryngology & Otology, Volume 130 Issue 03, pp 318-318 [image: S0022215116000086a_abstract.jpg] Read moreTop - Clarithromycin, m...περισσότερα »
OtoRhinoLaryngology,New Articles,February 16th,2016
OtoRhinoLaryngology - Alexandros G. Sfakianakis - Helicobacter pylori positive or negative children with resistant otitis media with effusionAlexandros G. Sfakianakis, 2016-02-16 09:23:28 AM Outcome evaluation of clarithromycin, metronidazole and lansoprazole regimens in Helicobacter pylori positive or negative children with resistant otitis media with effusion: Letter S S Bakshi, The Journal of Laryngology & Otology, Volume 130 Issue 03, pp 318-318 [image: S0022215116000086a_abstract.jpg] Read moreTop - Clarithromycin, me...περισσότερα »
Talking Medical Exoskeletons with CEO of US Bionics (Live Hangout Today @ 1 pm EST)
[image: SuitX]A couple weeks ago *US Bionics* introduced the Phoenix exoskeleton device that lets people with a variety of disabilities, including lower limb paralysis, walk on their own feet again. It is perhaps the lightest and one of the cheapest medical exoskeletons and we're excited to have Homayoon Kazerooni, the CEO of US Bionics, join us for a live hangout today at 1 pm EST, 10 am PST. Check out the preview of the technology and come back right to this page at the time listed above when we'll have the hangout embedded instead of the video: Flashback: Phoenix, a New Lightw... περισσότερα »
Talking Medical Exoskeletons with CEO of US Bionics (Live Hangout Today @ 1 pm EST)
[image: SuitX]A couple weeks ago *US Bionics* introduced the Phoenix exoskeleton device that lets people with a variety of disabilities, including lower limb paralysis, walk on their own feet again. It is perhaps the lightest and one of the cheapest medical exoskeletons and we're excited to have Homayoon Kazerooni, the CEO of US Bionics, join us for a live hangout today at 1 pm EST, 10 am PST. Check out the preview of the technology and come back right to this page at the time listed above when we'll have the hangout embedded instead of the video: Flashback: Phoenix, a New Lightw... περισσότερα »
Clarithromycin, metronidazole and lansoprazole regimens in Helicobacter pylori positive or negative children with resistant otitis media with effusion
Outcome evaluation of clarithromycin, metronidazole and lansoprazole regimens in Helicobacter pylori positive or negative children with resistant otitis media with effusion: Letter S S Bakshi, The Journal of Laryngology & Otology, Volume 130 Issue 03, pp 318-318
Smoking cessation
Main ArticlesYou can't pay me to quit: the failure of financial incentives for smoking cessation in head and neck cancer patientsA Ghosha1 c1, G Philiponisa1, A Bewleya2, E R Ransoma3 and N Mirzaa1 a1 Department of Otorhinolaryngology: Head and Neck Surgery, University of Pennsylvania, Philadelphia, USA a2 Department of Otorhinolaryngology, University of California, Davis, USA a3 Center for Facial Plastic, Reconstructive, and Laser Surgery, San Francisco, California, USA Abstract Objective: A prospective randomised study was conducted at a tertiary care hospital to evaluate the effects...περισσότερα »
Pooled analysis of the evidence for open cavity, combined approach and reconstruction of the mastoid cavity in primary cholesteatoma surgery
Main ArticlesPooled analysis of the evidence for open cavity, combined approach and reconstruction of the mastoid cavity in primary cholesteatoma surgeryA T Harrisa1, B Mettiasa1 and T H J Lessera1 c1 a1 ENT department, Aintree University Hospital, Liverpool, UK Abstract Background: Cholesteatoma is keratinising epithelium within the middle-ear cleft or mastoid. This disease destroys the peripheral organs of balance and hearing, with possible intracranial sequelae. The management of cholesteatoma is surgical and the primary aim is to remove the disease and prevent recurrence. Secondar...περισσότερα »
Medications for Ménière's disease?
Medications for Ménière's disease?: Editorial Robin Youngs, Edward Fisher, Musheer Hussain, Jonathan Fishman, The Journal of Laryngology & Otology, Volume 130 Issue 03, pp 213-213
Spezifische Anosmie als Prinzip olfaktorischer Wahrnehmung
Spezifische Anosmie als Prinzip olfaktorischer Wahrnehmung: ZusammenfassungSpezifische Anosmie ist die Unfähigkeit, einen bestimmten Geruch wahrzunehmen, während die allgemeine Riechverarbeitung unbeeinträchtigt ist. Dies war bisher als ein eher seltenes Phänomen bekannt. In unseren Studien haben wir die Prävalenz spezifischer Anosmien auf 20 verschiedene Geruchsstoffe bei 1600 Probanden überprüft. Aus diesen Daten ließ sich die Prävalenz für spezifische Anosmien auf Gerüche im Allgemeinen abschätzen und es zeigte sich, dass spezifische Anosmien keineswegs ein seltenes Phänomen sin... περισσότερα »
Häufigkeit und Komplikationen von MRT-Untersuchungen bei Cochlea-Implantat-Patienten
Häufigkeit und Komplikationen von MRT-Untersuchungen bei Cochlea-Implantat-Patienten: Zusammenfassung HintergrundDas Cochlea-Implantat (CI) ist die Behandlung der Wahl bei schwerer bis hochgradiger Schallempfindungsschwerhörigkeit, sowie bei einseitiger Ertaubung. Bedingt durch das bei Magnetresonanztomographieuntersuchungen (Magnetresonanztomographie – MRT) bestehende Magnetfeld, waren MRT-Untersuchungen bei CI-Trägern über viele Jahre kontraindiziert bzw. nur unter spezifischen Bedingungen durchführbar. MRT-Untersuchungen bei CI-Trägern bergen die Gefahr von Komplikationen und ... περισσότερα »
Perioperative Pain Control in the Ambulatory Setting
Perioperative Pain Control in the Ambulatory Setting: AbstractAcross the USA and various parts of the world, ambulatory surgery centers have transitioned to accepting patients with advanced ASA statuses, leading to a larger volume and higher complexity of surgeries performed, while still urging for same-day patient discharges. Inadequate postoperative pain management and opioid analgesia side effects, such as sedation, respiratory depression, and postoperative nausea and vomiting, are the most common complications and most common reasons for readmission after ambulatory surgery. Th...περισσότερα »
Salvage total laryngectomy after external-beam radiotherapy: A 20-year experience
otolaryngologistsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.Alexandros,,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,tel : 00302841026182,00306932607174Πριν από 12 δευτερόλεπτα
Abstract Background The purpose of this study was to present our evaluation of the clinical and functional outcomes after salvage total laryngectomy (STL). Methods We conducted a retrospective review of 218 patients who underwent STL between 1994 and 2014. Results Seventy percent of patients originally had T1 or T2, N0 tumors and 73% had definitive […]
Red Ear Syndrome
Red Ear Syndrome: AbstractThe Red ear syndrome (RES) is an intriguing syndrome originally described for the first time nearly 20 years ago. RES is characterized by unilateral/bilateral episodes of pain and burning sensation of the ear, associated with ipsilateral erythema. RES episodes are indeed isolated in some patients, but they can occur in association with primary headaches, including in particular migraine in the developmental age. Although the underlying pathophysiological mechanisms are still uncertain, in the recent years the described comorbidities have aroused increasing... περισσότερα »
Post-herpetic Neuralgia
Post-herpetic Neuralgia: a Review: AbstractPost-herpetic neuralgia (PHN) is a chronic neuropathic pain condition that persists 3 months or more following an outbreak of shingles. Shingles, also known as acute herpes zoster, is associated with the reactivation of the dormant varicella zoster virus in an individual who has experienced chicken pox. PHN is associated with persistent and often refractory neuropathic pain. Patients may experience multiple types of pain including a constant deep, aching, or burning pain; a paroxysmal, lancinating pain; hyperalgesia (painful stimuli are mo... περισσότερα »
Headache and Facial Pain in Sickle Cell Disease
Headache and Facial Pain in Sickle Cell Disease: AbstractChildren and adolescents with sickle cell disease (SCD) have a high prevalence of recurrent headaches (24.0–43.9 %). Acute presentation with headache can be diagnostically challenging, as the clinician must consider evaluation of several potentially devastating conditions including vascular diseases (stroke, hemorrhage, venous sinus thrombosis, moyamoya, posterior reversible encephalopathy syndrome), facial and orbital bone infarcts, dental pain, and osteomyelitis. Patients with SCD and primary headache disorders may benefit ... περισσότερα »
New Pain Management Options for the Surgical Patient on Methadone and Buprenorphine
New Pain Management Options for the Surgical Patient on Methadone and Buprenorphine: AbstractPerioperative management of patients receiving opioid addiction therapy presents a unique challenge for the anesthesiologist. The goal of pain management in this patient population is to effectively manage postoperative pain, to improve patient satisfaction and outcomes, and to reduce the cost of health care. Multimodal analgesics, including nonsteroid anti-inflammatory drugs, intravenous acetaminophen, gabapentanoid agents, and low-dose ketamine infusions, have been used to improve postope...περισσότερα »
Annales françaises d'Oto-rhino-laryngologie et de Pathologie Cervico-faciale
ScienceDirect Publication: Annales françaises d'Oto-rhino-laryngologie et de Pathologie Cervico-faciale - Editorial Board2016-02-16 09:18:24 AM Publication date: February 2016 *Source:*Annales françaises d'Oto-rhino-laryngologie et de Pathologie Cervico-faciale, Volume 133, Issue 1 Read moreTop - Point sur votre journal en ce début d’année 20162016-02-16 09:18:24 AM Publication date: February 2016 *Source:*Annales françaises d'Oto-rhino-laryngologie et de Pathologie Cervico-faciale, Volume 133, Issue 1 Author(s): C. Marti... περισσότερα »
Comment reconstruire les pertes de substances latérales de la pointe et de la supra-pointe de moins de 1,5cm de diamètre
Comment reconstruire les pertes de substances latérales de la pointe et de la supra-pointe de moins de 1,5cm de diamètre via ScienceDirect Publication: Annales françaises d'Oto-rhino-laryngologie et de Pathologie Cervico-faciale Publication date: February 2016 *Source:*Annales françaises d'Oto-rhino-laryngologie et de Pathologie Cervico-faciale, Volume 133, Issue 1 Author(s): M. Durbec, F. Disant Nous décrivons à travers cet article la technique chirurgicale ainsi que les indications et les limites du lambeau East-West Flap pour assurer la réparation des pertes de substance latérales d... περισσότερα »
Photorhabdus luminescens LN2 requires rpoS for nematicidal activity and nematode development
*Photorhabdus* (Enterobacteriaceae) bacteria are pathogenic to insects and mutualistic with entomopathogenic *Heterorhabditis* nematodes*. P. luminescens* subsp. *akhurstii* LN2, associated with *H. indica* LN2, shows nematicidal activity against *H. bacteriophora* H06 infective juveniles (IJs). In the present study, an *rpoS* mutant of *P. luminescens* LN2 was generated through allelic exchange to examine the effects of *rpoS* deletion on the nematicidal activity and nematode development. The results showed that *P. luminescens* LN2 required *rpoS* for nematicidal activity agains...περισσότερα »
Exposure of Metarhizium acridum mycelium to light induces tolerance to UV-B radiation
*Metarhizium acridum* is an entomopathogenic fungus commonly used as a bioinsecticide. The conidium is the fungal stage normally employed as field inoculum in biological control programs and must survive under field conditions such as high ultraviolet-B exposure. Light, which is an important stimulus for many fungi, has been shown to induce the production of *Metarhizium robertsii* conidia with increased stress tolerance. Here we show that a two-hour exposure to white or blue/UV-A light of fast-growing mycelium induces tolerance to subsequent UV-B irradiation. Red light, however, ... περισσότερα »
Anatomical study of the dorsal cutaneous branch of the ulnar nerve (DCBUN) and its clinical relevance in TFCC Repair
Publication date: Available online 15 February 2016 *Source:*Journal of Plastic, Reconstructive & Aesthetic Surgery Author(s): A.R. Poublon, G. Kraan, S.P. Lau, A.L.A. Kerver, G.-J. Kleinrensink The aim of this study was to define a detailed description of the Dorsal Cutaneous Branch of the Ulnar Nerve (DCBUN) in particular in relevance to TFCC repairs.In twenty formalin-embalmed arms, the DCBUN was dissected, and the course in each arm was mapped and categorized. Furthermore, the point where the DCBUN originates from the ulnar nerve in relation to the ulnar styloid process was defi...περισσότερα »
Photorhabdus luminescens LN2 requires rpoS for nematicidal activity and nematode development
*Photorhabdus* (Enterobacteriaceae) bacteria are pathogenic to insects and mutualistic with entomopathogenic *Heterorhabditis* nematodes*. P. luminescens* subsp. *akhurstii* LN2, associated with *H. indica* LN2, shows nematicidal activity against *H. bacteriophora* H06 infective juveniles (IJs). In the present study, an *rpoS* mutant of *P. luminescens* LN2 was generated through allelic exchange to examine the effects of *rpoS* deletion on the nematicidal activity and nematode development. The results showed that *P. luminescens* LN2 required *rpoS* for nematicidal activity agains...περισσότερα »
Exposure of Metarhizium acridum mycelium to light induces tolerance to UV-B radiation
*Metarhizium acridum* is an entomopathogenic fungus commonly used as a bioinsecticide. The conidium is the fungal stage normally employed as field inoculum in biological control programs and must survive under field conditions such as high ultraviolet-B exposure. Light, which is an important stimulus for many fungi, has been shown to induce the production of *Metarhizium robertsii* conidia with increased stress tolerance. Here we show that a two-hour exposure to white or blue/UV-A light of fast-growing mycelium induces tolerance to subsequent UV-B irradiation. Red light, however, ... περισσότερα »
Infection of an internal carotid artery plaque with vancomycin resistant enterococcus
*European Journal of Vascular and Endovascular SurgeryVolume 26, Issue 3, Pages 332–333* *Case Report* Infection of an internal carotid artery plaque with vancomycin resistant enterococcus * *- R. Vorou-Papavassiliou1, - V.G. Papavassiliou1, - A. Swann2, - A.R. Naylor, 1* * Show more* *doi:10.1053/ejvs.2002.1952* * Open Archive* ------------------------------ Abstract *Eur J Vasc Endovasc Surg 26, 332-333 (2003)* ------------------------------ Introduction *The first reported case of infection of a carotid plaque with vancomycin resistant enterococcus (VRE) is described.* C... περισσότερα »
Artérite infectieuse de l’artère carotide interne compliquant un abcès rétropharyngé
Artérite infectieuse de l’artère carotide interne compliquant un abcès rétropharyngé via ScienceDirect Publication: Annales françaises d'Oto-rhino-laryngologie et de Pathologie Cervico-faciale Publication date: February 2016 *Source:*Annales françaises d'Oto-rhino-laryngologie et de Pathologie Cervico-faciale, Volume 133, Issue 1 Author(s): Q. Lisan, H. Tran, B. Verillaud, P. Herman [image: Scanner cervical injecté. Rétrécissement de l’artère carotide interne gauche ...] [image: IRM en coupe axiale en séquence T1 FAT SAT avec injection de ...] IntroductionLes abcès rétropharyngés const... περισσότερα »
Rhinosclérome trachéal
Rhinosclérome trachéal via ScienceDirect Publication: Annales françaises d'Oto-rhino-laryngologie et de Pathologie Cervico-faciale Publication date: February 2016 *Source:*Annales françaises d'Oto-rhino-laryngologie et de Pathologie Cervico-faciale, Volume 133, Issue 1 Author(s): A. Bigi, M. Bartolomeo, V. Costes, M. Makeieff [image: Endoscopie laryngo-trachéal.] [image: TDM cervico-thoracique montrant un rétrécissement trachéal de 5 centimètres de ...] [image: Lame d’histologie par coloration de Whartin Starry. Macrophages renfermant des ...] IntroductionLe rhinosclérum trachéal est u...περισσότερα »
Neurofibrome rétropharyngé
: à propos d’un cas clinique rare et revue de la littérature via ScienceDirect Publication: Annales françaises d'Oto-rhino-laryngologie et de Pathologie Cervico-faciale Publication date: February 2016 *Source:*Annales françaises d'Oto-rhino-laryngologie et de Pathologie Cervico-faciale, Volume 133, Issue 1 Author(s): I. Atallah, J. Gervasoni, E. Gay, C.A. Righini IntroductionLes lésions de l’espace rétropharyngé sont des lésions rares.Cas cliniqueNous présentons un cas clinique rare de neurofibrome rétropharyngé traité chirurgicalement par voie cervicale.DiscussionLes neurofibromes so... περισσότερα »
La septoplastie endoscopique aux techniques conventionnelles
Revue de la littérature comparant via ScienceDirect Publication: Annales françaises d'Oto-rhino-laryngologie et de Pathologie Cervico-faciale Publication date: February 2016 *Source:*Annales françaises d'Oto-rhino-laryngologie et de Pathologie Cervico-faciale, Volume 133, Issue 1 Author(s): C. Champagne, S. Ballivet de Régloix, L. Genestier, A. Crambert, O. Maurin, Y. Pons L’objectif de cette revue de la littérature était de comparer la septoplastie endoscopique aux techniques conventionnelles en termes de gain de temps opératoire, d’efficacité fonctionnelle et de diminution de la mo...περισσότερα »
Alpha-synuclein gene variants may predict neurostimulation outcome
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 20 δευτερόλεπτα
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Corticostriatal plasticity modulation: New roads for therapeutic targets
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 20 δευτερόλεπτα
from #AlexandrosSfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/20AvZDq via IFTTT
Longitudinal Measurements of Cerebrospinal Fluid Biomarkers in Parkinson’s Disease
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 20 δευτερόλεπτα
ABSTRACT Objective The purpose of this study was to investigate whether cerebrospinal fluid (CSF) levels of tau, phosphorylated tau, β-amyloid42, α-synuclein, neurofilament light, and YKL-40 change over time and if changes correlate with motor progression and/or cognitive decline in patients with PD and controls. Methods We included 63 patients with PD (nondemented) and 21 neurologically […]
Parkinson’s disease-related fatigue: A case definition and recommendations for clinical research
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 20 δευτερόλεπτα
ABSTRACT Fatigue is one of the most common and disabling symptoms in Parkinson’s disease (PD). Since fatigue was first described as a common feature of PD 20 years ago, little progress has been made in understanding its causes or treatment. Importantly, PD patients attending the 2013 World Parkinson Congress voted fatigue as the leading symptom […]
Exponentially growing osteosarcoma of mandible with acromegaly
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 20 δευτερόλεπτα
ABSTRACT Background Osteosarcoma of the head and neck is aggressive malignancy that might be affected by growth hormone. The purpose of this study was to demonstrate an unusual case of osteosarcoma with acromegaly. Methods and Results This case is about a 39-year-old woman with an osteosarcoma of the mandible, who had a history of exponential […]
Psychological factors associated with failure of detoxification treatment in chronic headache associated with medication overuse
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 20 δευτερόλεπτα
Aim The aim of this study was to evaluate the psychological factors associated with a negative outcome following detoxification in a 2-month follow-up in medication-overuse headache. Methods All consecutive patients entering the detoxification program were analysed in a prospective, non-randomised fashion. Psychiatric conditions and personality characteristics were assessed using the Structured Clinical Interview for DSM-IV […]
A rare occurrence of basal cell adenoma of palate: A case report with comprehensive immunohistochemical analysis
Alexandros G. SfakianakisστοHead,Neck,Brain,Cervical Spine and Esophageal Cancers by Alexandros G. SfakianakisΠριν από 22 δευτερόλεπτα
Surinder Pal Singh Sodhi, Ramandeep Singh Brar, Harkanwal Preet Singh, Tajinder Kaur, Rohan DhawanJournal of Cancer Research and Therapeutics 2015 11(4):1023-1023Basal cell adenoma (BCA) of the salivary glands is an uncommon type of monomorphic adenoma which constitutes 1% of all salivary gland tumors. It most commonly involves parotid gland, while it rarely occurs in minor salivary glands. Upper lip, buccal mucosa, and lower lip are the common intraoral sites; whereas, palate being the rarest one. Due to prognostic implications, differential diagnosis with basal cell adenocarcino...περισσότερα »
Adenosquamous carcinoma of oral cavity
Alexandros G. SfakianakisστοHead,Neck,Brain,Cervical Spine and Esophageal Cancers by Alexandros G. SfakianakisΠριν από 22 δευτερόλεπτα
Prasanth Thanakappan, Naga Sirisha Chundru Venkata, Rajesh Amudala, Meeramma BotuJournal of Cancer Research and Therapeutics 2015 11(4):1034-1034 Adenosquamous carcinoma is a rare malignant epithelial neoplasm characterized by the presence of both areas of squamous cell carcinoma and adenocarcinoma. Only few cases of oral adenosquamous carcinoma have been previously reported in the literature. It has been described as a squamous cell carcinoma subtype with a high infiltrative capacity. This paper reports a rare case of adenosquamous carcinoma that involved the upper left buccal mu... περισσότερα »
APOBEC3B is an enzymatic source of molecular alterations in esophageal squamous cell carcinoma
Alexandros G. SfakianakisστοHead,Neck,Brain,Cervical Spine and Esophageal Cancers by Alexandros G. SfakianakisΠριν από 22 δευτερόλεπτα
Abstract APOBEC3B belongs to the cytidine deaminase apolipoprotein B mRNA-editing enzyme catalytic polypeptide-like (APOBEC3) family of enzymes and induces C to T transitions of target DNA by cytidine deamination. Recently, several mutations in various cancers have been linked to APOBEC3B, suggesting a crucial role for this protein in carcinogenesis and cancer development. However, the significance of APOBEC3B in esophageal squamous cell carcinoma (ESCC) remains uncertain. In addition, the APOBEC3B immunoreactivity in cancer tissues is uncertain. Recently, we have demonstrated that... περισσότερα »
1 May News
from #Infections via alexandrossfakianakis on Inoreader http://ift.tt/1KSXMx2 via IFTTT
Determinants of a low CD4/CD8 ratio in HIV-1-infected individuals despite long-term viral suppression
Despite long term HIV suppression, two-thirds of individuals still have a CD4/CD8 <1. Independent risk factors for such a profile are CMV seropositivity, ART initiation before 1997, a lower CD4 nadir and a shorter duration of viral suppression. from #Infections via alexandrossfakianakis on Inoreader http://ift.tt/1Tks8K7 via IFTTT
Changes of soil prokaryotic communities after clear cutting in a karst forest: evidences for cutting-based disturbance promoting deterministic processes
To understand the temporal responses of soil prokaryotic communities to clear cutting disturbance, we examined the changes in soil bacterial and archaeal community composition, structure and diversity along a chronosequence of forest successional restoration using high throughput 16S rRNA gene sequencing. Our results demonstrated that clear-cutting significantly altered soil bacterial community structure, while no significant shifts of soil archaeal communities were observed. The hypothesis that soil bacterial communities would become similar to those of surrounding intact primary...περισσότερα »
Sarcomes des tissus mous de la tête et du cou de l’adulte
Sarcomes des tissus mous de la tête et du cou de l’adulte via ScienceDirect Publication: Annales françaises d'Oto-rhino-laryngologie et de Pathologie Cervico-faciale Publication date: February 2016 *Source:*Annales françaises d'Oto-rhino-laryngologie et de Pathologie Cervico-faciale, Volume 133, Issue 1 Author(s): C. Galy-Bernadoy, R. Garrel Les sarcomes des tissus mous de l’adulte sont des tumeurs agressives et rares, avec environ 5 nouveaux cas par an pour 100 000 habitants. La localisation cervico-céphalique est peu représentée. Des maladies génétiques et l’irradiation favorisent le...περισσότερα »
La qualité de vie des enfants implantés cochléaires
Auto- et hétéroévaluation de via ScienceDirect Publication: Annales françaises d'Oto-rhino-laryngologie et de Pathologie Cervico-faciale Publication date: February 2016 *Source:*Annales françaises d'Oto-rhino-laryngologie et de Pathologie Cervico-faciale, Volume 133, Issue 1 Author(s): T. Razafimahefa-Raoelina, A. Farinetti, R. Nicollas, J.-M. Triglia, S. Roman, L. Anderson ButLe but de cette étude est de mesurer la qualité de vie des enfants implantés cochléaires par une approche combinée d’auto- et hétéroévaluation.Patients et méthodesTrente-deux enfants, âgés de 6 à 17 ans, sourds... περισσότερα »
La commissure antérieure du larynx
: histopathologie après laryngectomies partielles supracricoïdiennes via ScienceDirect Publication: Annales françaises d'Oto-rhino-laryngologie et de Pathologie Cervico-faciale Publication date: February 2016 *Source:*Annales françaises d'Oto-rhino-laryngologie et de Pathologie Cervico-faciale, Volume 133, Issue 1 Author(s): J.-M. Prades, M. Gavid, J.-M. Dumollard, A.-T. Timoshenko, A. Karkas, M. Peoc’h ObjectifsAnalyser les modalités d’envahissement histopathologique de la commissure antérieure du larynx sur les pièces opératoires de patients opérés d’un carcinome épidermoïde de stad...περισσότερα »
Une tuméfaction inhabituelle du pavillon
: le rhabdomyosarcome de l’oreille externe chez l’enfant via ScienceDirect Publication: Annales françaises d'Oto-rhino-laryngologie et de Pathologie Cervico-faciale Publication date: February 2016 *Source:*Annales françaises d'Oto-rhino-laryngologie et de Pathologie Cervico-faciale, Volume 133, Issue 1 Author(s): M. Chirat, L. Dainese, S. Fasola, V. Couloigner, F. Denoyelle, E.-N. Garabedian, N. Leboulanger IntroductionLes rhabdomyosarcomes (RMS) sont les plus fréquents des sarcomes des tissus mous de l’enfant et représentent 5 % de toutes les tumeurs malignes pédiatriques. Les princi... περισσότερα »
Goitres plongeants
: expérience du service à propos de 50 cas via ScienceDirect Publication: Annales françaises d'Oto-rhino-laryngologie et de Pathologie Cervico-faciale Publication date: February 2016 *Source:*Annales françaises d'Oto-rhino-laryngologie et de Pathologie Cervico-faciale, Volume 133, Issue 1 Author(s): M. Benbakh, M. Abou-elfadl, S. Rouadi, R.-L. Abada, M. Roubal, M. Mahtar IntroductionUn goitre correspond à une hypertrophie localisée ou généralisée du corps thyroïde. Il est habituellement cervical mais peut avoir un développement intrathoracique en dépassant l’orifice supérieur du thor...περισσότερα »
Les carcinomes adénoïdes kystiques ORL
: une étude multicentrique prospective REFCOR de 95 cas via ScienceDirect Publication: Annales françaises d'Oto-rhino-laryngologie et de Pathologie Cervico-faciale Publication date: February 2016 *Source:*Annales françaises d'Oto-rhino-laryngologie et de Pathologie Cervico-faciale, Volume 133, Issue 1 Author(s): M. Meyers, B. Granger, P. Herman, F. Janot, R. Garrel, N. Fakhry, G. Poissonnet, B. Baujat But du travailIl s’agit de décrire les caractéristiques cliniques, histologiques et thérapeutiques d’une série prospective multicentrique de 95 patients atteints d’un carcinome adénoïde ... περισσότερα »
Lambeau libre de fibula dans le traitement de l’ostéoradionécrose mandibulaire
Lambeau libre de fibula dans le traitement de l’ostéoradionécrose mandibulaire via ScienceDirect Publication: Annales françaises d'Oto-rhino-laryngologie et de Pathologie Cervico-faciale Publication date: February 2016 *Source:*Annales françaises d'Oto-rhino-laryngologie et de Pathologie Cervico-faciale, Volume 133, Issue 1 Author(s): S. Baron, D. Salvan, L. Cloutier, I. Gharzouli, N. Le Clerc IntroductionL’ostéoradionécrose mandibulaire (ORNm) constitue une des complications majeures de la radiothérapie dans le traitement des cancers ORL. Elle est responsable d’importantes douleurs et...περισσότερα »
Quality of neck dissection operative reports
Quality of neck dissection operative reports: The operative report is the official documentation of an operation and a key form of surgical communication. The objective of this study is to assess completeness of operative reports for neck dissections. *Abstract**Purpose* The operative report is the official documentation of an operation and a key form of surgical communication. The objective of this study is to assess completeness of operative reports for neck dissections. *Methods* This is a retrospective review of narrative operative reports for neck dissections for head and nec... περισσότερα »
Aglossia
Case Report: Introduction Aglossia is a rare condition caused by failure of the tongue embryogenesis process (in the fourth to eighth weeks of gestation). The tongue is an organ used in different activities such as sucking, swallowing, chewing, and talking. It is also responsible for shaping palate dental arches (in its absence, they become atrophic). There are few similar cases reported in the literature. Objective To describe a rare case of aglossia and the multidisciplinary professionals working together for 5 years to treat the patient. Resumed Report An 8-year-old girl with agl... περισσότερα »
The Video Head Impulse Test in a Case of Suspected Bilateral Loss of Vestibular Function
The Video Head Impulse Test in a Case of Suspected Bilateral Loss of Vestibular Function: Introduction A patient who had no symptoms suggestive of bilateral loss of vestibular function presented no responses in rotational and caloric tests. Objectives To demonstrate the importance of the video head impulse test in neurootologic diagnosis. Resumed Report This patient had a neuro-otologic evaluation and presented no responses in torsion swing tests, caloric tests, and rotational tests in a Bárány chair. The video head impulse test elicited responses in four of the six semicircular can... περισσότερα »
Mastoid Obliteration with Autologous Bone
Mastoid Obliteration with Autologous Bone in Mastoidectomy Canal Wall Down Surgery: a Literature Overview: Introduction The objectives of mastoidectomy in cholesteatoma are a disease-free and dry ear, the prevention of recurrent disease, and the maintenance of hearing or the possibility to reconstruct an affected hearing mechanism. Canal wall down mastoidectomy has been traditionally used to achieve those goals with greater or lesser degrees of success. However, canal wall down is an aggressive approach, as it involves creating an open cavity and changing the anatomy and physiology ... περισσότερα »
Cochlear Implantation and Single-sided Deafness
Cochlear Implantation and Single-sided Deafness: A Systematic Review of the Literature: Introduction Current data show that binaural hearing is superior to unilateral hearing, specifically in the understanding of speech in noisy environments. Furthermore, unilateral hearing reduce oné s ability to localize sound. Objectives This study provides a systematic review of recent studies to evaluate the outcomes of cochlear implantation in patients with single-sided deafness (SSD) with regards to speech discrimination, sound localization and tinnitus suppression. Data Synthesis We performe... περισσότερα »
Vertiginous Symptoms and Objective Measures of Postural Balance in Elderly People with Benign Paroxysmal Positional Vertigo Submitted to the Epley Maneuver
Vertiginous Symptoms and Objective Measures of Postural Balance in Elderly People with Benign Paroxysmal Positional Vertigo Submitted to the Epley Maneuver: Introduction Benign Paroxysmal Positional Vertigo (BPPV) is one of themost common and treatable causes of peripheral vestibular vertigo in adults. Its incidence increases with age, eventually leading to disability and a decreased quality of life. Objective The research aims to assess short-term effects of Otolith Repositioning Maneuver (ORM) on dizziness symptoms, quality of life, and postural balance in elderly people with Beni...περισσότερα »
The Impact of Dizziness
The Impact of Dizziness on the Quality of Life of 235 Individuals who Completed Vestibular Testing in Brazil: Introduction In Vestibular Testing (VT), caloric tests allow evaluation of unilateral weakness (UW) and directional preponderance (DP), where different criteria of normality are adopted in Brazil and worldwide. The Brazilian version of the Dizziness Handicap Inventory (Brazilian DHI) evaluates the impact of dizziness on the quality of life of an individual. Objectives The objective of this research is to evaluate the impact of dizziness on the quality of life of patients und... περισσότερα »
Self-Assessment of Hearing and Purchase of Hearing Aids by Middle-Aged and Elderly Adults
Self-Assessment of Hearing and Purchase of Hearing Aids by Middle-Aged and Elderly Adults: Introduction Presbycusis is a consequence of aging. Prescription of hearing aids is part of the treatment, although the prevalence of use by elderly people is still small. Objective To verify whether or not self-assessment of hearing is a predictor for purchase of hearing aids. Methods Quantitative, cross-sectional, descriptive, and observational study. Participants were subjects who sought a private hearing center for selection of hearing aids. During the diagnostic interview, subjects answer... περισσότερα »
Prevention of the Evolution of Workers' Hearing Loss from Noise-Induced Hearing Loss in Noisy Environments through a Hearing Conservation Program
Prevention of the Evolution of Workers' Hearing Loss from Noise-Induced Hearing Loss in Noisy Environments through a Hearing Conservation Program: Introduction Noise-induced hearing loss (NIHL) is a serious problem for workers and therefore for businesses. The hearing conservation program (HCP) is a set of coordinated measures to prevent the development or evolution of occupational hearing loss, which involves a continuous and dynamic process of implementation of hearing conservation routines through anticipation, recognition, evaluation, and subsequent control of the occurrence of ...περισσότερα »
Functional Outcomes after Stapes Surgery
Evaluation of Functional Outcomes after Stapes Surgery in Patients with Clinical Otosclerosis in a Teaching Institution: Introduction Otosclerosis is a primary disease of the temporal bone that leads to stapes ankylosis. Hearing loss is the main symptom. Treatment includes surgery, medical treatment, and sound amplification therapy alone or in combination. Objective To evaluate the functional outcomes of patients with clinical diagnosis of otosclerosis undergoing primary stapes surgery in a teaching institution. Method Retrospective descriptive study. Results A total of 210 ears of ... περισσότερα »
Vibrant Soundbridge and Bone Conduction Hearing Aid in Patients with Bilateral Malformation of External Ear
Vibrant Soundbridge and Bone Conduction Hearing Aid in Patients with Bilateral Malformation of External Ear: Introduction Hearing loss is the most common clinical finding in patients with malformation of the external ear canal. Among the possibilities of treatment, there is the adaptation of hearing aids by bone conduction and the adaptation of implantable hearing aids. Objective To assess speech perception with the use of Vibrant Soundbridge (VBS - MED-EL, Innsbruck, Austria) associated with additional amplification in patients with bilateral craniofacial malformation. Method We ev...περισσότερα »
Extrapulmonary Head and Neck Tuberculosis
Clinical Study of Extrapulmonary Head and Neck Tuberculosis: A Single-Institute 10-year Experience: Introduction Although the incidence of tuberculosis (TB) in Japan has been decreasing yearly, Japan remains ranked as an intermediate-burden country for TB. Objective This study aims to investigate the current situation of head and neck extrapulmonary TB (EPTB) diagnosed in our department. Methods We retrospectively reviewed the clinical records of 47 patients diagnosed with EPTB in the head and neck in our department between January 2005 and December 2014. The extracted data included...περισσότερα »
Vocal Parameters of Elderly Female Choir Singers
Vocal Parameters of Elderly Female Choir Singers: Introduction Due to increased life expectancy among the population, studying the vocal parameters of the elderly is key to promoting vocal health in old age. Objective This study aims to analyze the profile of the extension of speech of elderly female choristers, according to age group. Method The study counted on the participation of 25 elderly female choristers from the Choir of Messianic Church of São Paulo, with ages varying between 63 and 82 years, and an average of 71 years (standard deviation of 5.22). The elders were divided ...περισσότερα »
Correlation of Vocal Intensity with Velopharyngeal Closing Mechanism in Individuals with and without Complaint of Velopharyngeal Dysfunction
Correlation of Vocal Intensity with Velopharyngeal Closing Mechanism in Individuals with and without Complaint of Velopharyngeal Dysfunction: Introduction Velopharyngeal sphincter is a portion of the muscle of the palatopharyngeal arch that is capable of separating the oral cavity from the nasal cavity. It has not been determined yet whether voice intensity has an influence on this capacity. Velopharyngeal sphincter closure is accomplished by elevating and retracting the soft palate at the same time as the nasopharyngeal walls are constricted. Objective This study aims to correlate ... περισσότερα »
Effectiveness of Chin-tuck Maneuver to Facilitate Swallowing in Neurologic Dysphagia
Effectiveness of Chin-tuck Maneuver to Facilitate Swallowing in Neurologic Dysphagia: Introduction The chin-tuck maneuver is the most frequently employed postural maneuver in the treatment of neurogenic oropharyngeal dysphagia caused by encephalic vascular strokes and degenerative diseases. Objective The purpose of this study was to investigate the effectiveness of this maneuver in patients with neurogenic dysphagia and factors that could interfere in it. Methods In this retrospective cohort, we analyzed the medical files and videofluoroscopy exams of 35 patients (19male - 54% and 1...περισσότερα »
Subcutaneous Immunotherapy Improves the Symptomatology of Allergic Rhinitis
Subcutaneous Immunotherapy Improves the Symptomatology of Allergic Rhinitis: Introduction The relevance of allergic rhinitis is unquestionable. This condition affects people s quality of life and its incidence has increased over the last years. Objective Thus, this study aims to analyze the effectiveness of subcutaneous injectable immunotherapy in cases of nasal itching, sneeze, rhinorrhea and nasal congestion in allergic rhinitis patients. Methods In the present study, the same researcher analyzed the records of 281 patients. Furthermore, the researchers identified allergens throug... περισσότερα »
Anaplastic thyroid carcinoma: Failure of conventional therapy but hope of targeted therapy
Anaplastic thyroid carcinoma: Failure of conventional therapy but hope of targeted therapy: [image: cover.gif?v=1&s=f31d30ee0afa0d30e14f3c30] Abstract Background Anaplastic thyroid cancer has a median survival between 1.2 and 10 months. The purpose of our study was to evaluate the outcomes of patients with anaplastic thyroid cancer in Ireland. Methods We carried out a retrospective analysis of the Irish National Cancer Database for patients with anaplastic thyroid cancer between 2000 and 2010. Results Of a total of 64 patients (40 women, 24 men), the median age was 69 years, and ... περισσότερα »
Salvage total laryngectomy after external-beam radiotherapy
Salvage total laryngectomy after external-beam radiotherapy: A 20-year experience: Abstract Background The purpose of this study was to present our evaluation of the clinical and functional outcomes after salvage total laryngectomy (STL). Methods We conducted a retrospective review of 218 patients who underwent STL between 1994 and 2014. Results Seventy percent of patients originally had T1 or T2, N0 tumors and 73% had definitive external-beam radiotherapy (EBRT) alone. A majority utilized tracheoesophageal prosthesis (77%) and were gastrostomy free (80%) at last follow-up. The 5-ye...περισσότερα »
Tumor infiltrating lymphocytes and survival in patients with head and neck squamous cell carcinoma
Tumor infiltrating lymphocytes and survival in patients with head and neck squamous cell carcinoma: Abstract Background Because immune responses within the tumor microenvironment are important predictors of tumor biology, correlations of types of tumor infiltrating lymphocytes (TILs) with clinical outcomes were determined in 278 patients with head and neck squamous cell carcinoma (HNSCC). Methods Infiltrating levels of CD4 (helper T cells), CD8 (cytotoxic/suppressor T cells), FoxP3 (regulatory T cells), CD68 (myeloid-derived suppressor cells,) and CD1a (Langerhans) cells were measur...περισσότερα »
Exponentially growing osteosarcoma of mandible with acromegaly
Exponentially growing osteosarcoma of mandible with acromegaly: [image: cover.gif?v=1&s=f31d30ee0afa0d30e14f3c30] ABSTRACT Background Osteosarcoma of the head and neck is aggressive malignancy that might be affected by growth hormone. The purpose of this study was to demonstrate an unusual case of osteosarcoma with acromegaly. Methods and Results This case is about a 39-year-old woman with an osteosarcoma of the mandible, who had a history of exponential tumor growth in spite of chemotherapy at another hospital. She transferred to Samsung Medical Center and underwent a wide resec... περισσότερα »
Endocrinology and Metabolism
- The Endocrine Society of India - A way forwardShashank R Joshi, 2016-02-15 00:00:00 AM *Shashank R Joshi, Krishna G Seshadri* Indian Journal of Endocrinology and Metabolism 2016 20(2):149-150 Read moreTop - Of statins and low-density lipoprotein cholesterol, “fats” and fictionAmbika Gopalakrishnan Unnikrishnan, 2016-02-15 00:00:00 AM *Ambika Gopalakrishnan Unnikrishnan, Sanjay Kalra, Ambrish Mithal* Indian Journal of Endocrinology and Metabolism 2016 20(2):151-153 Read moreTop - Empagliflozin: Not just a glorified diureticMathew Joh... περισσότερα »
Parkinson’s disease-related fatigue: A case definition and recommendations for clinical research
ABSTRACT Fatigue is one of the most common and disabling symptoms in Parkinson’s disease (PD). Since fatigue was first described as a common feature of PD 20 years ago, little progress has been made in understanding its causes or treatment. Importantly, PD patients attending the 2013 World Parkinson Congress voted fatigue as the leading symptom… Continue reading Parkinson’s disease-related fatigue: A case definition and recommendations for clinical research
Directed block copolymer self-assembly implemented via surface-embedded electrets
Article The controlled orientation of block copolymers promises to deliver high resolution patterning for implementation in future nanoscale technologies. Here, the authors use the electric field from charged electrets to induce extremely localised perpendicularly oriented microdomains in polymer thin films. Nature Communications doi: 10.1038/ncomms10752 Authors: Mei-Ling Wu, Dong Wang, Li-Jun Wan from #Medicine-SfakianakisAlexandros via o.lakala70… Continue reading Directed block copolymer self-assembly implemented via surface-embedded electrets
Exponentially growing osteosarcoma of mandible with acromegaly
ABSTRACT Background Osteosarcoma of the head and neck is aggressive malignancy that might be affected by growth hormone. The purpose of this study was to demonstrate an unusual case of osteosarcoma with acromegaly. Methods and Results This case is about a 39-year-old woman with an osteosarcoma of the mandible, who had a history of exponential… Continue reading Exponentially growing osteosarcoma of mandible with acromegaly
GAME9 regulates the biosynthesis of steroidal alkaloids and upstream isoprenoids in the plant mevalonate pathway
Article Steroidal glycoalkaloids (SGAs) accumulate in solanaceous plants and contribute to plant defence but are toxic to humans. Here the authors show that the GAME9 transcription factor is a regulator of the SGA biosynthetic pathways providing a potential way to manipulate SGA levels in crops. Nature Communications doi: 10.1038/ncomms10654 Authors: Pablo D. Cárdenas, Prashant D.… Continue reading GAME9 regulates the biosynthesis of steroidal alkaloids and upstream isoprenoids in the plant mevalonate pathway
Tumor infiltrating lymphocytes and survival in patients with head and neck squamous cell carcinoma
Abstract Background Because immune responses within the tumor microenvironment are important predictors of tumor biology, correlations of types of tumor infiltrating lymphocytes (TILs) with clinical outcomes were determined in 278 patients with head and neck squamous cell carcinoma (HNSCC). Methods Infiltrating levels of CD4 (helper T cells), CD8 (cytotoxic/suppressor T cells), FoxP3 (regulatory T cells),… Continue reading Tumor infiltrating lymphocytes and survival in patients with head and neck squamous cell carcinoma
Salvage total laryngectomy after external-beam radiotherapy: A 20-year experience
Abstract Background The purpose of this study was to present our evaluation of the clinical and functional outcomes after salvage total laryngectomy (STL). Methods We conducted a retrospective review of 218 patients who underwent STL between 1994 and 2014. Results Seventy percent of patients originally had T1 or T2, N0 tumors and 73% had definitive… Continue reading Salvage total laryngectomy after external-beam radiotherapy: A 20-year experience
Observations of narrow bipolar events reveal how lightning is initiated in thunderstorms
Article How lightning is initiated inside storms has been a long-standing and fundamental question. Here, the authors report observations of a previously unrecognized type of discharge, called fast positive breakdown, that is found to initiate many and potentially all lightning discharges in storms. Nature Communications doi: 10.1038/ncomms10721 Authors: William Rison, Paul R. Krehbiel, Michael G.… Continue reading Observations of narrow bipolar events reveal how lightning is initiated in thunderstorms
Gut immunity in a protochordate involves a secreted immunoglobulin-type mediator binding host chitin and bacteria
Article Protochordates, including Ciona intestinalis , lack an adaptive immune system but possess innate immune receptors, including the secreted immunoglobulin V-region-containing VCBPs. Here the authors show that VCBP-C of Ciona binds gut bacteria and chitin-rich gut mucosa, influences biofilm formation and likely plays a role in gut homeostasis. Nature Communications doi: 10.1038/ncomms10617 Authors: Larry J.… Continue reading Gut immunity in a protochordate involves a secreted immunoglobulin-type mediator binding host chitin and bacteria
Anaplastic thyroid carcinoma: Failure of conventional therapy but hope of targeted therapy
Abstract Background Anaplastic thyroid cancer has a median survival between 1.2 and 10 months. The purpose of our study was to evaluate the outcomes of patients with anaplastic thyroid cancer in Ireland. Methods We carried out a retrospective analysis of the Irish National Cancer Database for patients with anaplastic thyroid cancer between 2000 and 2010.… Continue reading Anaplastic thyroid carcinoma: Failure of conventional therapy but hope of targeted therapy
Psychological factors associated with failure of detoxification treatment in chronic headache associated with medication overuse
Aim The aim of this study was to evaluate the psychological factors associated with a negative outcome following detoxification in a 2-month follow-up in medication-overuse headache. Methods All consecutive patients entering the detoxification program were analysed in a prospective, non-randomised fashion. Psychiatric conditions and personality characteristics were assessed using the Structured Clinical Interview for DSM-IV… Continue reading Psychological factors associated with failure of detoxification treatment in chronic headache associated with medication overuse
Talking Medical Exoskeletons with CEO of US Bionics (Live Hangout Today @ 1 pm EST)
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 30 δευτερόλεπτα
A couple weeks ago US Bionics introduced the Phoenix exoskeleton device that lets people with a variety of disabilities, including lower limb paralysis, walk on their own feet again. It is perhaps the lightest and one of the cheapest medical exoskeletons and we’re excited to have Homayoon Kazerooni, the CEO of US Bionics, join us […]
APOBEC3B is an enzymatic source of molecular alterations in esophageal squamous cell carcinoma
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 30 δευτερόλεπτα
Abstract APOBEC3B belongs to the cytidine deaminase apolipoprotein B mRNA-editing enzyme catalytic polypeptide-like (APOBEC3) family of enzymes and induces C to T transitions of target DNA by cytidine deamination. Recently, several mutations in various cancers have been linked to APOBEC3B, suggesting a crucial role for this protein in carcinogenesis and cancer development. However, the significance […]
CD20-targeting immunotherapy promotes cellular senescence in B-cell lymphoma
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 30 δευτερόλεπτα
The CD20-targeting monoclonal antibody Rituximab is an established component of immunochemotherapeutic regimens against B-cell lymphomas, where its co-administration with conventional anti-cancer agents has significantly improved long-term outcome. However, the cellular mechanisms by which Rituximab exerts its anti-lymphoma activity are only partially understood. We show here that Rituximab induces typical features of cellular senescence, a long-term […]
APOBEC3B is an enzymatic source of molecular alterations in esophageal squamous cell carcinoma
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 30 δευτερόλεπτα
Abstract APOBEC3B belongs to the cytidine deaminase apolipoprotein B mRNA-editing enzyme catalytic polypeptide-like (APOBEC3) family of enzymes and induces C to T transitions of target DNA by cytidine deamination. Recently, several mutations in various cancers have been linked to APOBEC3B, suggesting a crucial role for this protein in carcinogenesis and cancer development. However, the significance […]
Open Versus Closed Hearing-Aid Fittings: A Literature Review of Both Fitting Approaches
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 30 δευτερόλεπτα
One of the main issues in hearing-aid fittings is the abnormal perception of the user’s own voice as too loud, “boomy,” or “hollow.” This phenomenon known as the occlusion effect be reduced by large vents in the earmolds or by open-fit hearing aids. This review provides an overview of publications related to open and closed […]
Incidence of dementia declined in past 30 years in US, study shows
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 30 δευτερόλεπτα
from Uncategorized via xlomafota13 on Inoreader http://ift.tt/1PNSZtq via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1oFtJ1M via IFTTT
‘Inflammatory myofibroblastic tumor’-like dedifferentiation of ALK-rearranged lung adenocarcinoma
Abstract Aims Anaplastic lymphoma kinase (ALK) functions as an oncogenic driver in a subset of hematopoietic, epithelial and mesenchymal neoplasms. Activation of ALK most commonly occurs through gene fusion events, the presence of which predicts response to ALK-targeted inhibitors in some tumor types. Echinoderm microtubule-associated protein-like 4-ALK (EML4-ALK) fusions represent the majority of ALK rearrangements in lung adenocarcinomas and were, until recently, thought to be exclusive to that tumor type. However, recent work has identified EML4-ALK fusions in approximately 20%...περισσότερα »
The Laryngoscope
- Incus footplate assembly: Indication and surgical outcomeMina Park, Sungjun Han, Byung Yoon Choi, Sun O Chang, Chong Sun Kim, Ja-Won Koo, 2016-02-16 08:35:35 AM Objectives/Hypothesis To review surgical findings and hearing outcomes of incus footplate assembly (IFA) for the patients with conductive hearing loss due to missing stapes superstructure with a mobile stapes footplate. Study Design Retrospective case review and survey. Methods Pre- and postoperative audiometric data and intraoperative findings were reviewed. Postoperative air-bone gap (A... περισσότερα »
International Journal of Pharmaceutical Investigation (Int J Pharma Investig)
Insulin delivery methods: Past, present and future *Rima B Shah, Manhar Patel, David M Maahs, Viral N Shah* International Journal of Pharmaceutical Investigation 2016 6(1):1-9 Many patients with advanced type 2 diabetes mellitus (T2DM) and all patients with T1DM require insulin to keep blood glucose levels in the target range. The most common route of insulin administration is subcutaneous insulin injections. There are many ways to deliver insulin subcutaneously such as vials and syringes, insulin pens, and insulin pumps. Though subcutaneous insulin delivery is the standard route of... περισσότερα »
Incus footplate assembly
: Indication and surgical outcomeMina Park, Sungjun Han, Byung Yoon Choi, Sun O Chang, Chong Sun Kim, Ja-Won Koo, 2016-02-16 08:35:35 AM Objectives/Hypothesis To review surgical findings and hearing outcomes of incus footplate assembly (IFA) for the patients with conductive hearing loss due to missing stapes superstructure with a mobile stapes footplate. Study Design Retrospective case review and survey. Methods Pre- and postoperative audiometric data and intraoperative findings were reviewed. Postoperative air-bone gap (ABG) and ABG closure (postoperative air-conduction threshold–preo... περισσότερα »
Photodermatology, Photoimmunology & Photomedicine
Photoaggravated pompholyx Pompholyx is a type of eczema characterised by a pruritic vesicular eruption occurring on the lateral fingers, hands and feet (1,2). Many etiological factors such as atopy, contact allergy, adverse drug reactions, dermatophyte and HIV infection are reportedly associated, and stress, smoking, irritants and prolonged use of protective gloves are said to be aggravating factors (2). One of the important cutaneous adverse effects of intravenous immunoglobulin (IVIG) was pompholyx, which developed in 62.5% of the 64 patients who had eczematous reactions to IVIG (... περισσότερα »
Radiofrequency Thermal Ablation versus Bipolar Electrocautery for the Treatment of Inferior Turbinate Hypertrophy: Comparison of Efficacy and Postoperative Morbidity
Radiofrequency Thermal Ablation versus Bipolar Electrocautery for the Treatment of Inferior Turbinate Hypertrophy: Comparison of Efficacy and Postoperative Morbidity: Introduction Numerous surgical methods are used to treat nasal obstruction due to inferior turbinate hypertrophy. The primary goal of the therapy is to maximize the nasal airway for as extended a period of time as possible while minimizing therapeutic complications. Objectives The aim of this study was to assess the effects of radiofrequency thermal ablation (RFTA) and bipolar electrocautery (BEC) on the removal of nas...περισσότερα »
Open Versus Closed Hearing-Aid Fittings: A Literature Review of Both Fitting Approaches
One of the main issues in hearing-aid fittings is the abnormal perception of the user's own voice as too loud, "boomy," or "hollow." This phenomenon known as the occlusion effect be reduced by large vents in the earmolds or by open-fit hearing aids. This review provides an overview of publications related to open and closed hearing-aid fittings. First, the occlusion effect and its consequences for perception while using hearing aids are described. Then, the advantages and disadvantages of open compared with closed fittings and their impact on the fitting process are addressed. The ... περισσότερα »
Carotid Endarterectomy After Intravenous Thrombolysis: The Sooner the Better?
Publication date: Available online 15 February 2016 *Source:*European Journal of Vascular and Endovascular Surgery Author(s): M. Koelemay, P. Nederkoorn from Endocrinology via ola Kala on Inoreader http://ift.tt/1ViyRTT via IFTTT
Psychological factors associated with failure of detoxification treatment in chronic headache associated with medication overuse
Aim The aim of this study was to evaluate the psychological factors associated with a negative outcome following detoxification in a 2-month follow-up in medication-overuse headache. Methods All consecutive patients entering the detoxification program were analysed in a prospective, non-randomised fashion. Psychiatric conditions and personality characteristics were assessed using the Structured Clinical Interview for DSM-IV Disorders (SCID-I) and the Minnesota Multiphasic Personality Inventory (MMPI)-2. 2 tests, one-way analyses of variance, and odds ratios (ORs) were used. Res...περισσότερα »
Open Versus Closed Hearing-Aid Fittings: A Literature Review of Both Fitting Approaches
otolaryngologistsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.Alexandros,,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,tel : 00302841026182,00306932607174Πριν από 1 ώρα
One of the main issues in hearing-aid fittings is the abnormal perception of the user’s own voice as too loud, «boomy,» or «hollow.» This phenomenon known as the occlusion effect be reduced by large vents in the earmolds or by open-fit hearing aids. This review provides an overview of publications related to open and closed […]
Virome-associated antibiotic-resistance genes in an experimental aquaculture facility
otolaryngologistsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.Alexandros,,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,tel : 00302841026182,00306932607174Πριν από 1 ώρα
We report the comprehensive characterization of viral and microbial communities within an aquaculture wastewater sample, by a shotgun sequencing and 16S rRNA gene profiling metagenomic approach. Caudovirales had the largest representation within the sample, with over 50% of the total taxonomic abundance, whereas approximately 30% of the total open reading frames (ORFs) identified were from […]
Requirement of interleukin 7 signaling for anti-tumor immune response under lymphopenic conditions in a murine lung carcinoma model
otolaryngologistsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.Alexandros,,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,tel : 00302841026182,00306932607174Πριν από 1 ώρα
Abstract Induction of lymphopenia before adoptive transfer of T cells was followed by lymphopenia-induced proliferation (LIP) and generated a potent anti-tumor immune response in rodents and in a clinical setting. Previously, we reported that CD28 signaling is essential for the differentiation of functional effector cytotoxic T lymphocytes (CTLs) under lymphopenic conditions and sequential LIP of […]
Changes of soil prokaryotic communities after clear cutting in a karst forest: evidences for cutting-based disturbance promoting deterministic processes
otolaryngologistsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.Alexandros,,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,tel : 00302841026182,00306932607174Πριν από 1 ώρα
To understand the temporal responses of soil prokaryotic communities to clear cutting disturbance, we examined the changes in soil bacterial and archaeal community composition, structure and diversity along a chronosequence of forest successional restoration using high throughput 16S rRNA gene sequencing. Our results demonstrated that clear-cutting significantly altered soil bacterial community structure, while no significant […]
Diversity of the nitrogen starvation responses in subarctic Desmodesmus sp. (Chlorophyceae) strains isolated from symbioses with invertebrates
otolaryngologistsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.Alexandros,,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,tel : 00302841026182,00306932607174Πριν από 1 ώρα
We report on common and strain-specific responses to nitrogen (N) starvation recorded in four closely related symbiotic Desmodesmus strains from taxonomically very distant animals (hydroids, a sponge, and a polychaete) dwelling in the White Sea. A number of common for the studied strains and free-living microalgae as well as some specific patterns of acclimation to […]
Characterisation of the faecal bacterial community of wild young South American (Arctocephalus australis) and Subantarctic fur seals (Arctocephalus tropicalis)
otolaryngologistsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.Alexandros,,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,tel : 00302841026182,00306932607174Πριν από 1 ώρα
The microbiota of wild marine mammals is poorly understood, perhaps due to the migratory habits of some species and the difficulty in obtaining samples. Using high-throughput sequencing, the present study examines the faecal bacterial community of wild young South American (Arctocephalus australis) and Subantarctic fur seals (Arctocephalus tropicalis). Faecal samples from South American (n = […]
Unification of Sinonasal Anatomical Terminology
otolaryngologistsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.Alexandros,,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,tel : 00302841026182,00306932607174Πριν από 1 ώρα
from #ORL-Sfakianakis via xlomafota13 on Inoreader http://ift.tt/1QiAZ9V via IFTTT
Radiofrequency Thermal Ablation versus Bipolar Electrocautery for the Treatment of Inferior Turbinate Hypertrophy: Comparison of Efficacy and Postoperative Morbidity
otolaryngologistsfakianakisστοOtoRhinoLaryngology by Sfakianakis G.Alexandros,,Anapafseos 5 Agios Nikolaos 72100 Crete Greece,tel : 00302841026182,00306932607174Πριν από 1 ώρα
Introduction Numerous surgical methods are used to treat nasal obstruction due to inferior turbinate hypertrophy. The primary goal of the therapy is to maximize the nasal airway for as extended a period of time as possible while minimizing therapeutic complications. Objectives The aim of this study was to assess the effects of radiofrequency thermal ablation […]
Conformational Dynamics and Allostery in Pyruvate Kinase Protein Structure and Folding
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Pyruvate kinase catalyses the final step in glycolysis and is allosterically regulated to control flux through the pathway. Two models are proposed to explain how Escherichia coli pyruvate kinase type 1 is allosterically regulated: the ‘domain rotation model’ suggests that both the domains within the monomer and the monomers within the tetramer reorient with respect […]
Hiatal hernia
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Hiatal hernia: An anatomical abnormality in which part of the stomach protrudes up through the diaphragm into the chest. Normally, the esophagus passes down through the chest, crosses the diaphragm, enters the abdomen through a hole in the diaphragm called the esophageal hiatus and joins the stomach just below the diaphragm. When there is a […]
2016 European guideline on donovanosis
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Donovanosis is a rare sexually transmitted infection now mainly seen in sporadic cases in Papua New Guinea, South Africa, India, Brazil and Australia. The causative organism is Calymmatobacterium granulomatis though a proposal has been put forward that the organism be reclassified as Klebsiella granulomatis comb nov. The incubation period is approximately 50 days with genital […]
Bone marrow-derived cells in ocular neovascularization: contribution and mechanisms
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Abstract Ocular neovascularization often leads to severe vision loss. The role of bone marrow-derived cells (BMCs) in the development of ocular neovascularization, and its significance, is increasingly being recognized. In this review, we discuss their contribution and the potential mechanisms that mediate the effect of BMCs on the progression of ocular neovascularization. The sequence of […]
Accounting for Wetland Loss: Wetland Mitigation Trends in Northeast Florida 2006–2013
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Abstract The realization of wetland ‘no net loss’ policy under Section 404 of the Clean Water Act remains uncertain, as mitigation practices force a trade-off in on-site mitigation with loss of biological integrity and off-site mitigation with a redistribution of ecosystem services. Wetlands cover 25 % of the Lower St. Johns River Basin (LSJRB), northeastern […]
Effective percutaneous “edge-to-edge” mitral valve repair with mitraclip in a patient with acute post-MI regurgitation not related to papillary muscle rupture
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
A 65-year-old woman was admitted to our institution for rest dyspnea and hypotension. EKG showed sinus tachycardia with signs of infero-posterior STEMI. 2D-echocardiogram showed severe left ventricular systolic dysfunction with a- diskynesia of the inferior and posterior walls and severe functional mitral regurgitation (MR). The patient underwent urgent coronary angiography that showed 3-vessels disease with […]
Definition of Oesophagus – Cops 2.0
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Definition of Oesophagus Cops 2.0 Barretts ailment, barrett’s esophagus cancer signs of illness, barrett’s esophagus adenocarcinoma Barretts Disease, Barrett’s Esophagus Cancer Symptoms, Barrett’s Esophagus Adenocarcinoma Are somebody lost, scared, frustrated, or confused? and more » from #AlexandrosSfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1KmugzA via IFTTT
Mg++ requirement for MtHK binding, and Mg++ stabilization of mitochondrial membranes via activation of MtHK & MtCK and promotion of mitochondrial permeability transition pore closure: A hypothesis on mechanisms underlying Mg++’s antioxidant and cytoprotective effects
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Publication date: 25 April 2016 Source:Gene, Volume 581, Issue 1 Author(s): Shiva Golshani-Hebroni Evidence points to magnesium’s antioxidant, anti-necrotic, and anti-apoptotic effects in cardio- and neuroprotection. With magnesium being involved in over 300 biochemical reactions, the mechanisms underlying its cytoprotective and antioxidant effects have remained elusive. The profound anti-apoptotic, anabolic, and antioxidant effects of mitochondrion […]
Identification of novel isoforms of dairy goat EEF1D and their mRNA expression characterization
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Publication date: 25 April 2016 Source:Gene, Volume 581, Issue 1 Author(s): Sihuan Zhang, Xianfeng Wu, Chuanying Pan, Chuzhao Lei, Ruihua Dang, Hong Chen, Xianyong Lan Eukaryotic translation elongation factor 1 delta (EEF1D) gene encodes guanine nucleotide exchange protein eEF1Bδ, which participates in the eukaryotic protein synthesis, and plays important roles in regulating cell cycling and […]
Validation of housekeeping genes as an internal control for gene expression studies in Giardia lamblia using quantitative real-time PCR
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Publication date: 25 April 2016 Source:Gene, Volume 581, Issue 1 Author(s): Jaime Marcial-Quino, Francisco Fierro, Ignacio De la Mora-De la Mora, Sergio Enríquez-Flores, Saúl Gómez-Manzo, America Vanoye-Carlo, Itzhel Garcia-Torres, Edgar Sierra-Palacios, Horacio Reyes-Vivas The analysis of transcript levels of specific genes is important for understanding transcriptional regulation and for the characterization of gene function. Real-time […]
Effect of Standard Physical Therapy Protocol on Two Different Techniques of Same Non-Anatomical Repair Procedure of Anterior Shoulder Instability
AlexAndros SfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026Πριν από 1 ώρα
2016-02-15T21-07-08Z *Source:* International Journal of Therapies and Rehabilitation Research Hesham Ahmed Ali, Aliaa Mohammed Rehan, Khaled Al-Sayed Ayaad, Walid Reda Awadallah. Background & Purpose, Non-anatomical repair is the only choice in presence of bony defect in anterior shoulder instability, few evidence based rehabilitation protocol try to return the patients to a fully functional status; this study try to investigate effect of either labrum preservation or removal on shoulder function and proprioception in patients with same surgical procedure. Subjects & Methods, Twenty...περισσότερα »
‘Inflammatory myofibroblastic tumor’-like dedifferentiation of ALK-rearranged lung adenocarcinoma
Abstract Aims Anaplastic lymphoma kinase (ALK) functions as an oncogenic driver in a subset of hematopoietic, epithelial and mesenchymal neoplasms. Activation of ALK most commonly occurs through gene fusion events, the presence of which predicts response to ALK-targeted inhibitors in some tumor types. Echinoderm microtubule-associated protein-like 4-ALK (EML4-ALK) fusions represent the majority of ALK rearrangements in lung adenocarcinomas and were, until recently, thought to be exclusive to that tumor type. However, recent work has identified EML4-ALK fusions in approximately 20%...περισσότερα »
Resolvin D1, resolvin D2 and maresin 1 activate the GSK3{beta} anti-inflammatory axis in TLR4-engaged human monocytes
Pro-resolving, docosahexaenoic acid-derived mediators have recently emerged as important potential therapeutic agents for the amelioration of complications arising from inflammation, such as vascular disease, asthma, acute lung injury and colitis. While resolvin D1 (RVD1), resolvin D2 (RVD2) and maresin 1 (MaR1) are established pro-resolvins, their mechanisms of action remain unclear. Here we show that, in LPS-stimulated primary human monocytes, RVD1, RVD2 and MaR1 each suppress the release of pro-inflammatory cytokines (TNF, IL-1β, IL-8) and the innate/adaptive bridging cytokine,...περισσότερα »
Carbamylated LL-37 as a modulator of the immune response
Carbamylation of lysine residues and protein *N*-termini is an ubiquitous, non-enzymatic post-translational modification. Carbamylation at sites of inflammation is due to cyanate formation during the neutrophil oxidative burst and may target lysine residues within the antimicrobial peptide LL-37. The bactericidal and immunomodulatory properties of LL-37 depend on its secondary structure and cationic nature, which are conferred by arginine and lysine residues. Therefore, carbamylation may affect the biological functions of LL-37. The present study examined the kinetics and pattern ...περισσότερα »
HIV counselling and testing practices for children seen in an urban emergency department of a tertiary referral hospital in Dar es Salaam, Tanzania: a retrospective cross-sectional study
Objectives To describe the HIV counselling and testing practices for children presenting to an emergency department (ED) in a low-income country. Setting The ED of a large east African national referral hospital. Participants This retrospective review of all paediatric (<18 years old) ED visits in 2012 enrolled patients who had an HIV test ordered and… Continue reading HIV counselling and testing practices for children seen in an urban emergency department of a tertiary referral hospital in Dar es Salaam, Tanzania: a retrospective cross-sectional study
Role of Macrophages in Wound-Induced Skin Cancer
Macrophages are essential for the progression and maintenance of many cancers, but their role during the earliest stages of tumor formation is unclear. To test this, we used a previously described transgenic mouse model of wound-induced skin tumorigenesis, in which expression of constitutively active MEK1 in differentiating epidermal cells results in chronic inflammation (InvEE mice).… Continue reading Role of Macrophages in Wound-Induced Skin Cancer
CD74-NRG1 Fusion Gene Product Confers Cancer Stem Cell Properties
In this study, we found that the expression of the CD74-NRG1 fusion gene increased the population of lung cancer cells with CSC-like properties. CD74-NRG1 expression facilitated sphere formation not only of cancer cells, but also of nonmalignant lung epithelial cells. Using a limiting dilution assay in a xenograft model, we further show that the CD74-NRG1… Continue reading CD74-NRG1 Fusion Gene Product Confers Cancer Stem Cell Properties
Phenotypic flexibility of thermogenesis in the hwamei (Garrulax canorus): responses to cold acclimation
AlexAndros SfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026Πριν από 1 ώρα
Cold acclimation in birds involves a comprehensive array of physiological and morphological adjustment ranging from changes in aerobic enzyme activity to metabolic rate and organ mass. In the present study, we investigated phenotypic variation in thermogenic activity in the hwamei (*Garrulax canorus*) under normal (35°C) or cold (15°C) ambient temperature conditions. Acclimation to an ambient temperature of 15°C for 4 wk significantly increased the body mass, basal metabolic rate (BMR), and energy intake, including both gross energy intake and digestible energy intake, compared wi...περισσότερα »
Gender Differences in the Incidence of Depression Among Immigrants and Natives in Aragón, Spain
AlexAndros SfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026Πριν από 1 ώρα
Abstract Knowledge of depression among immigrants within Spanish primary care is limited. This database study investigates the incidence of depressive disorders among immigrants and natives within primary care in Aragón (Spain). Participants were patients registered in an electronic record register, aged above 20 years diagnosed with depression. Incidence of depression was calculated and compared per continent of origin, gender and age with the Mann-Whitney U test and the Kruskal–Wallis test. The population consisted of 11,088 patients with depression of whom 93.0 % natives and 7....περισσότερα »
Undocumented Immigrant Women in Spain: A Scoping Review on Access to and Utilization of Health and Social Services
AlexAndros SfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026Πριν από 1 ώρα
Abstract This scoping review summarizes and analyzes relevant studies related to the evidence published on undocumented immigrant women's access to and utilization of health and social services in Spain. Scientific literature was identified by entering search terms in seven electronic databases which combined retrieved health sciences peer-reviewed articles (Pubmed, Embase, CINAHL Plus and Scopus) and grey literature databases (Europa OpenGrey, DART-Europe and Google Scholar) published between 2004 and 2014 and written in Spanish or in English presenting data about Spain. Those tha...περισσότερα »
Incidence of dementia declined in past 30 years in US, study shows
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 1 ώρα
from Uncategorized via xlomafota13 on Inoreader http://ift.tt/1PNSZcU via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1Odf7eU via IFTTT
Extended prediction rule to optimise early detection of heart failure in older persons with non-acute shortness of breath: a cross-sectional study
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 1 ώρα
Objectives There is a need for a practical tool to aid general practitioners in early detection of heart failure in the elderly with shortness of breath. In this study, such a screening rule was developed based on an existing rule for detecting heart failure in older persons with a diagnosis of chronic obstructive pulmonary disease. […]
The China Patient-Centred Evaluative Assessment of Cardiac Events (China PEACE)-Prospective Study of 3-Vessel Disease: rationale and design
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 1 ώρα
Introduction Complex coronary artery disease (left main and three-vessel disease) carries high risks of adverse events and cost burden. However, in China, little is known about which patients are directed toward which treatment strategies and what outcomes are being achieved. Methods and analysis Using the China PEACE (Patient-centered Evaluative Assessment of Cardiac Events) research network, […]
Safety and efficacy of insulin glargine 300 u/mL compared with other basal insulin therapies in patients with type 2 diabetes mellitus: a network meta-analysis
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 1 ώρα
Objective To compare the efficacy and safety of a concentrated formulation of insulin glargine (Gla-300) with other basal insulin therapies in patients with type 2 diabetes mellitus (T2DM). Design This was a network meta-analysis (NMA) of randomised clinical trials of basal insulin therapy in T2DM identified via a systematic literature review of Cochrane library databases, […]
SCALS: a fourth-generation study of assisted living technologies in their organisational, social, political and policy context
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 1 ώρα
Introduction Research to date into assisted living technologies broadly consists of 3 generations: technical design, experimental trials and qualitative studies of the patient experience. We describe a fourth-generation paradigm: studies of assisted living technologies in their organisational, social, political and policy context. Fourth-generation studies are necessarily organic and emergent; they view technology as part of […]
HIV counselling and testing practices for children seen in an urban emergency department of a tertiary referral hospital in Dar es Salaam, Tanzania: a retrospective cross-sectional study
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 1 ώρα
Objectives To describe the HIV counselling and testing practices for children presenting to an emergency department (ED) in a low-income country. Setting The ED of a large east African national referral hospital. Participants This retrospective review of all paediatric (<18 years old) ED visits in 2012 enrolled patients who had an HIV test ordered and […]
An integrated microfluidic chip for immunomagnetic detection and isolation of rare prostate cancer cells from blood
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 1 ώρα
Abstract The quantitative and qualitative analysis of circulating tumor cells (CTCs) has the potential to improve the clinical management of several cancers, including prostate cancer. As such, there is much interest in the isolation of CTCs from the peripheral blood of cancer patients. We report the design, fabrication, and proof-of-principle testing of an integrated permalloy-based […]
1 May News
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 1 ώρα
from #Infections via alexandrossfakianakis on Inoreader http://ift.tt/1KSXMx2 via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1oFtGD6 via IFTTT
Determinants of a low CD4/CD8 ratio in HIV-1-infected individuals despite long-term viral suppression
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 1 ώρα
Despite long term HIV suppression, two-thirds of individuals still have a CD4/CD8 <1. Independent risk factors for such a profile are CMV seropositivity, ART initiation before 1997, a lower CD4 nadir and a shorter duration of viral suppression. from #Infections via alexandrossfakianakis on Inoreader http://ift.tt/1Tks8K7 via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros […]
Extended prediction rule to optimise early detection of heart failure in older persons with non-acute shortness of breath: a cross-sectional study
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 1 ώρα
Objectives There is a need for a practical tool to aid general practitioners in early detection of heart failure in the elderly with shortness of breath. In this study, such a screening rule was developed based on an existing rule for detecting heart failure in older persons with a diagnosis of chronic obstructive pulmonary disease. […]
Thymustumoren
Zusammenfassung Hintergrund Thymustumoren, d. h. Thymome, Thymuskarzinome und -karzinoide, sind mit einer Inzidenz von 0,13/100.000 Einwohnern eine sehr seltene Entität. Material und Methoden Anhand einer Literaturrecherche wurden neuere Erkenntnisse zur Epidemiologie, Klassifikationen und verschiedenen Therapieansätzen recherchiert. Ergebnisse Die sehr verschiedenen Tumoren können lange klinisch inapparent bleiben, die eigentlichen Thymome (A, AB, B1, B2, B3) können Paraneoplasien verursachen, und Thymuskarzinome wachsen sehr aggressiv. Die chirurgische Resektion wird als der G... περισσότερα »
Early signet ring cell carcinoma arising from colonic adenoma: the molecular profiling supports the adenoma-carcinoma sequence
Publication date: April 2016 *Source:*Human Pathology, Volume 50 Author(s): Alberto Bellan, Rocco Cappellesso, Marcello Lo Mele, Laura Peraro, Laura Balsamo, Cristiano Lanza, Matteo Fassan, Massimo Rugge Among colorectal cancers, the prevalence of signet ring cell carcinoma (SRCC) is lower than 1%; to date, only 6 cases of early SRCCs arising in colonic adenoma have been reported. In spite of the well-established understanding of the phenotypic and genetic changes occurring in conventional colonic carcinogenesis, the molecular landscape of colon SRCC is still far to be elucidated. W...περισσότερα »
Genetic testing at UPMC pinpoints mutations to match patients, therapies – Tribune-Review
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Genetic testing at UPMC pinpoints mutations to match patients, therapies Tribune-Review He could wiggle his fingers and stick out his tongue. With a little instruction … Nikiforova recently tested a brain tumor that had mutations associated with bladder cancer, opening up the possibility of off-label treatment with a bladder cancer drug … from #AlexandrosSfakianakis via […]
Early stage primary ovarian mucinous carcinoma: Outcome-based clinicopathological study in comparison with serous carcinoma
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Objective To compare clinicopathological characteristics and survival rates between patients with primary ovarian mucinous carcinoma and those with primary ovarian serous carcinoma. Methods This retrospective study reviewed archival tumour specimens, originally diagnosed as primary ovarian mucinous carcinoma, using refined histological criteria. All patients were contacted to establish survival status. Clinicopathological characteristics and patient survival data […]
MiR-205 promotes proliferation, migration and invasion of nasopharyngeal carcinoma cells by activation of AKT signalling
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Objective To examine the role of microRNA (miR)-205 in proliferation, migration and invasion of nasopharyngeal carcinoma (NPC). Methods The human NPC cell line CNE2 was transfected with miR-205 mimic, anti-miR-205 inhibitor or scrambled oligonucleotide (control). Cell proliferation was assessed via MTT assay. Cell migration and invasion were evaluated by transwell migration and Matrigel® invasion assay, […]
Comparison of effects of intravenous midazolam and ketamine on emergence agitation in children: Randomized controlled trial
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Objective A prospective, double-blind, randomized controlled trial to compare the effect of preoperative midazolam or ketamine on the incidence of emergence agitation (EA) following sevoflurane anaesthesia in children. Methods Paediatric patients (2–6 years old) undergoing ophthalmic surgery were allocated to receive premedication with either 0.1 mg/kg midazolam or 1 mg/kg ketamine. Incidence of EA and […]
Epidermal growth factor and prostaglandin E2 levels in Helicobacter pylori-positive gastric intraepithelial neoplasia
sfakianakisdiseasesστοHuman Diseases Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Objective To investigate levels of epidermal growth factor (EGF) and prostaglandin E2 (PGE2) in Han Chinese patients with Helicobacter pylori-positive gastric low-grade intraepithelial neoplasia (LGIN). Methods In this prospective, observational study, gastric specimens from patients with LGIN were collected by gastroscopy with consecutive biopsy. EGF and PGE2 concentrations in serum and gastric juice from patients […]
HIV counselling and testing practices for children seen in an urban emergency department of a tertiary referral hospital in Dar es Salaam, Tanzania: a retrospective cross-sectional study
Objectives To describe the HIV counselling and testing practices for children presenting to an emergency department (ED) in a low-income country. Setting The ED of a large east African national referral hospital. Participants This retrospective review of all paediatric (<18 years old) ED visits in 2012 enrolled patients who had an HIV test ordered and excluded those without testing. Files were available for 5540/5774 (96%) eligible patients and 1632 (30%) were tested for HIV, median age 1.3 years (IQR 9 months to 4 years), 58% <18 months old and 61% male. Primary and secondary ... περισσότερα »
Open Versus Closed Hearing-Aid Fittings: A Literature Review of Both Fitting Approaches
One of the main issues in hearing-aid fittings is the abnormal perception of the user’s own voice as too loud, "boomy," or "hollow." This phenomenon known as the occlusion effect be reduced by large vents in the earmolds or by open-fit hearing aids. This review provides an overview of publications related to open and closed hearing-aid fittings. First, the occlusion effect and its consequences for perception while using hearing aids are described. Then, the advantages and disadvantages of open compared with closed fittings and their impact on the fitting process are addressed. The ... περισσότερα »
