Αρχειοθήκη ιστολογίου

Αλέξανδρος Γ. Σφακιανάκης
ΩτοΡινοΛαρυγγολόγος
Αναπαύσεως 5
Άγιος Νικόλαος Κρήτη 72100
2841026182
6032607174

Πέμπτη 28 Ιουλίου 2016

OtoRhinoLaryngology & Medicine,New Articles,July 28th,2016,afternoon


Orbital Expansion for Congenital Anophthalmia May Be Achievable in Infancy But Not in Childhood.
Orbital Expansion for Congenital Anophthalmia May Be Achievable in Infancy But Not in Childhood.: Background: Congenital anophthalmia is a rare anomaly that results in micro-orbitism and craniofacial microsomia. Treatment with static conformers is labor-intensive and provides minimal stimulation for...

Spectro-temporal receptive fields
Capturing contextual effects in spectro-temporal receptive fieldsvia Hearing ResearchPublication date: Available online 27 July 2016Source:Hearing ResearchAuthor(s): Johan Westö, Patrick J.C. MaySpectro-temporal receptive fields (STRFs) are thought to provide descriptive images of the computations performed...
Resorbable Materials for Reconstruction of the Orbital Floor in Children.
Resorbable Materials for Reconstruction of the Orbital Floor in Children.: The best treatment of pediatric orbital fractures is debated and different strategies are proposed in the literature. Resorbable materials, due to their features and the specific requirements of the pediatric population, seem...
Upregulation of cystathione β-synthase and p70S6K/S6 in neonatal hypoxic ischemic brain injury
Upregulation of cystathione β-synthase and p70S6K/S6 in neonatal hypoxic ischemic brain injury: ABSTRACTEncephalopathy of prematurity (EOP) is a complex form of cerebral injury that occurs in the setting of hypoxia-ischemia (HI) in premature infants. Using a rat model of EOP, we investigated whether...
Synergistic effect of honokiol and 5-fluorouracil on apoptosis of oral squamous cell carcinoma cells
Synergistic effect of honokiol and 5-fluorouracil on apoptosis of oral squamous cell carcinoma cells: Background5-Fluorouracil (5-FU) is an essential chemotherapeutic agent for oral squamous cell carcinoma (OSCC). However, toxic side effects have limited its role in OSCC therapy. The aim of this study...
Bioactive Saponins from Pittosporaceae, Polygalaceae, Mimosaceae, Sapindaceae, Apiaceae, Dioscoreaceae, and Asparagaceae
Newest Strategies in the Search for Bioactive Saponins from the Tropical Plant Biodiversity: This review will focus on newest results leading to the discovery of new bioactive saponins by using a combination of successive advanced procedures in extraction, isolation, structure elucidation and bioassays....
Clear-Cell (Reticulated) Transformation of Eyelid Eccrine Sweat Glands.
Clear-Cell (Reticulated) Transformation of Eyelid Eccrine Sweat Glands.: A 24-year-old man with a painful, recurrent left upper eyelid nodule underwent an excision. Histopathologic evaluation disclosed a granulomatous process, most likely in response to a ruptured epidermoid cyst. In the vicinity of...
Diplopia and Symblepharon Following Mueller's Muscle Conjunctival Resection in Patients on Long-Term Multiple Antiglaucoma Medications.
Diplopia and Symblepharon Following Mueller's Muscle Conjunctival Resection in Patients on Long-Term Multiple Antiglaucoma Medications.: To report the occurrence of diplopia and symblepharon following conjunctival Muellerectomy for ptosis repair in 3 patients under chronic antiglaucoma treatment. In...
Titanium T-Plate as a Platform for Globe Stabilization in Acquired Nystagmus and Oscillopsia Without a Null Zone.
Titanium T-Plate as a Platform for Globe Stabilization in Acquired Nystagmus and Oscillopsia Without a Null Zone.: A 49-year-old woman with debilitating nystagmus and oscillopsia failed conservative therapy. A titanium T-plate was anchored to the lateral orbital rim and cantilevered into the orbit where...
Neonatal Orbital Abscess Secondary to Pseudomonas Aeruginosa Conjunctivitis.
Neonatal Orbital Abscess Secondary to Pseudomonas Aeruginosa Conjunctivitis.: Pseudomonas aeruginosa conjunctivitis, although rare in healthy infants, may cause serious ocular and systemic complications. A 30-day-old, otherwise healthy male infant was referred with the diagnosis of right orbital abscess....
Transarterial Embolization of a Spontaneous Intraorbital Arteriovenous Fistula With n-BCA Glue.
Transarterial Embolization of a Spontaneous Intraorbital Arteriovenous Fistula With n-BCA Glue.: Arteriovenous fistulae of the orbit are exceedingly rare. They are high-flow vascular malformations involving a fistula from the ophthalmic artery to one of the draining ophthalmic veins. Presenting symptoms...
Neuroepithelial Cyst of the Optic Nerve in a Newborn.
Neuroepithelial Cyst of the Optic Nerve in a Newborn.: Cystic lesions of the optic nerve are uncommon findings that have been associated with neoplasms, systemic disorders, or described as idiopathic. They have been described in a wide range of ages, with few congenital cysts having been described in...
The combination of balloon Eustachian tuboplasty and tympanic paracentesis on intractable chronic otitis media with effusion
Article in PressEffect of Maojin Liang, MD, Hao Xiong, PhD, Yuexin Cai, Yuebo Chen, MD, Zhigang Zhang, MD, Suijun Chen, MD,Yaodong Xu, MD, Yongkang Ou, MD, Haidi Yang, PhD, Yiqing Zheng, MDPress enter key for correspondence informationPress enter key to Email the authorDepartment of Otolaryngology, Sun...
Smell function has been initiated with theophylline treatment in 63% of patients with Type II congenital smell loss
Article in PressOn the mechanism of smell loss in patients with Type II congenital hyposmia☆☆Robert I. Henkin, MD, PhDPress enter key for correspondence informationPress enter key to Email the author, Mona Abdelmeguid, MSPress enter key to Email the author, Alexandra B. Knöppel, BAPress enter key to...
Neck dissection operative technique
Article in PressHow, when, and from whom neck dissection operative technique is learned: An international survey on neck dissection education among head and neck oncologic surgeons☆Shirin Hemmat, BS, Steven J. Wang, MD, FACS, William R. Ryan, MD, FACSPress enter key for correspondence informationPress...
Sinonasal malignancy : When an unexpected diagnosis occurs, the pathology slides should be reviewed for a second opinion. If the unexpected diagnosis is confirmed, the tissue should undergo STR genetic analysis to ensure against tissue contamination.
Article in Press: What to do with an unexpected pathology result?Michael B. Hall, MDPress enter key for correspondence informationPress enter key to Email the author, Marc R. Rosen, MD, Kurren Gill, BA, Gurston G. Nyquist, MDThomas Jefferson University Hospital, Department of Otolaryngology-Head and...
Ccorticosteroids in Ménière's disease
Article in PressThe physiologic role of corticosteroids in Ménière's disease☆Zachary Farhood, MD, Paul R. Lambert, MDPress enter key for correspondence informationPress enter key to Email the authorDepartment of Otolaryngology — Head and Neck Surgery, Medical University of South Carolina, Charleston,...
The presence of two or more of the following features, DM, facial nerve palsy, positive CT scan and age above 70, predicts poor outcome, and highlights the need for prolonged, vigorous treatment.Malignant external otitis (MEO) : otalgia (89%), external ear canal edema (86%) and otorrhea (84%). Pseudomonas aeruginosa was isolated in 61% of ear cultures.
Article in PressMalignant external otitis: Factors predicting patient outcomes☆☆☆★Sagit Stern Shavit, MDPress enter key for correspondence informationPress enter key to Email the author, Ethan Soudry, MD, Yaniv Hamzany, MD, Ben Nageris, MDPress enter key for correspondence informationPress enter key...
Early hypoglossal-facial anastomotic repair after acute facial nerve injury is associated with better long-term facial function outcomes and should be considered in the management algorithm.
Article in PressFacial nerve repair after operative injury: Impact of timing on hypoglossal-facial nerve graft outcomes☆☆Robert J. Yawn, MD, Harry V. Wright, MD, David O. Francis, MD, MS, Scott Stephan, MD, Marc L. Bennett, MD, MMHCPress enter key for correspondence informationPress enter key to Email...
Bisphosphonate related osteonecrosis of calvarial bone
Article in PressJames Prueter, DOPress enter key for correspondence informationPress enter key to Email the author, Ambujakshan Dildeep, MDPress enter key to Email the authorDOI: http://dx.doi.org/10.1016/j.amjoto.2016.05.002Article InfoAbstractFull TextImagesReferencesAbstractBackgroundA case of bisphosphonate...
The orticochea flap for scalp reconstruction
Article in PressMultiflap closure of scalp defects: Revisiting Arvind Badhey, MDPress enter key to Email the author, Sameep Kadakia, MDPress enter key for correspondence informationPress enter key to Email the author, Manoj T. Abraham, MDPress enter key to Email the author, J.K. Rasamny, MDPress enter...
Pyoderma gangrenosum (PG) is a non-infectious inflammation of unknown cause, which includes dysregulation of the autoimmune system
Article in PressPyoderma gangrenosum misdiagnosed as a mucormycosis☆☆Jong Seung Kim, MD, Sam Hyun Kwon, MD, PhDPress enter key for correspondence informationPress enter key to Email the author, Sang Jae Noh, MD, PhDDOI: http://dx.doi.org/10.1016/j.amjoto.2016.05.005Article InfoAbstractFull TextImagesReferencesPyoderma...
Μαύρο κύμινο,φυτό Νιγέλα η εδώδιμος (Nigella sativa) ή άλλως η Νιγκέλλα ή τοΜελάνθιον το ήμερον,μαυρόσπορο και μαύροαγριοκύμινο)Thymoquinone was slightly better than methylprednisolone for functional nerve recovery
Article in PressThe histopathological and electrophysiological effects of thymoquinone and methylprednisolone in a rabbit traumatic facial nerve paralysis modelMurat SereflicanPress enter key for correspondence informationPress enter key to Email the author,Veysel Yurttas,Gulzade Ozyalvacli,Elcin Hakan...
EGb 761 is effective for treating NIHL during the early period
Article in PressTherapeutic efficacy of Ginkgo biloba for early-period noise-induced hearing loss: An experimental animal study☆Alev Pektaş Sjostrand, PhD, Remzi Dogan, MDPress enter key for correspondence informationPress enter key to Email the author, Abdurrahim Kocyigit, MD, Ersin Karatas, PhD,Bilgehan...
Oral cavity Adenoid cystic carcinoma ACC (OCACC) is a rare malignancy with females and whites being more commonly affected. At presentation, regional and distant metastases are uncommon. Poor prognostic indicators include male gender, nonsurgical therapy, nodal involvement, and distant metastasis.
Article in PressPopulation-based trends in outcomes in adenoid cystic carcinoma of the oral cavityPariket M. Dubal, DO, Aykut A. Unsal, DO, Sei Y. Chung, BS, Akshay V. Patel, DO, Richard Chan Woo Park, MD, FACS, Soly Baredes, MD, FACS, Jean Anderson Eloy, MD, FACSPress enter key for correspondence informationPress...
Palatopharyngoplasty for treatment of nasopharyngeal stenosis secondary to extra-laryngeal tuberculosis
Article in PressJeffrey Cranford, MDPress enter key to Email the author, Sameep Kadakia, MDPress enter key for correspondence informationPress enter key to Email the author, Craig Berzofsky, MDPress enter key to Email the authorDepartment of Otolaryngology–Head and Neck Surgery, New York Eye and Ear...
Tacrolimus has favorable effects on the healing process of the facial nerve after end-to-end anastomosis. Tacrolimus may be a promising agent in the future for nerve regeneration following traumatic facial paralysis surgery.
Article in PressThe effect of tacrolimus on facial nerve injury: Histopathological findings in a rabbit model☆☆☆★Kamil Gokce Tulaci, MDPress enter key for correspondence informationPress enter key to Email the authorPress enter key to Email the author, Arzu Tuzuner, MD, Hatice Karadas Emir, MD, İlkan...
OSCC's recurrent neck metastases : Cervical node management is vital for the successful treatment of oral squamous cell carcinoma (OSCC)
Article in PressInfluence of previous treatment of oral squamous cell carcinoma on the geographic distribution of recurrent neck metastases: A case series of unusual level 4 metastasesRosalie A. Machado, BAPress enter key for correspondence informationPress enter key to Email the author, Sami P. Moubayed,...
Transcanalicular Diode Laser Supported Endoscopic Dacryocystorhinostomy and Non-laser Endoscopic Dacryocystorhinostomy
Article in PressA comparative study of Gültekin Övet, MDPress enter key for correspondence informationPress enter key to Email the author, Yasar Sakarya, MDDOI: http://dx.doi.org/10.1016/j.amjoto.2016.07.003Article InfoAbstractFull TextReferencesAbstractObjectiveThe primary surgical procedure for nasolacrimal...
Bi-dimensional measurement of oral leukoplakia and RECIST criteria. Digital photography measurements, though highly correlative, are very cumbersome. We recommend bi-dimensional or longest length measurement and a simple photograph as standard of documentation for leukoplakia lesions.
Article in PressCorrelation Analysis of Oral Lesion Sizes by Various Standardized CriteriaCarrie E. Flanagan, M.D., Nelson L. Rhodus, D.M.D., M.P.H., Kate A. Cole, R.N., Eva Szabo, M.D., Frank G. Ondrey, M.D., Ph.D.Press enter key for correspondence informationPress enter key to Email the authorDOI: http://dx.doi.org/10.1016/j.amjoto.2016.07.004Article...
Video-assisted and open lateral neck dissection for papillary thyroid carcinoma with lateral neck lymph node metastases
Article in PressA comparative study of the surgical outcomes between ☆Deguang Zhang, Lei Xie, Gaofei He, Liang Fang, Yuwen Miao, Zhezhe Wang, Li GaoPress enter key for correspondence informationPress enter key to Email the authorHead and Neck Surgery Department of SIR RUN RUN SHAW Hospital, Institute...
Swallowing outcomes following cricopharyngeal (CP) dilation versus surgical myotomy in patients with dysphagia secondary to idiopathic CP bar
Article in PressTreatment of oropharyngeal dysphagia secondary to idiopathic cricopharyngeal bar: Surgical cricopharyngeal muscle myotomy versus dilation☆Alexander P. Marston, MDPress enter key for correspondence informationPress enter key to Email the author, Francisco J. Maldonado, BA, Karthik Ravi,...
Clinicopathologic characteristics and outcomes of recurrent oropharyngeal squamous cell carcinoma
Article in Press☆Chase M. Heaton, MDPress enter key for correspondence information1,Press enter key to Email the author, Karina Yu1, Sarah Calkins, MD1, Jonathan R. George, MD1, William R. Ryan, MD1, Steven J. Wang, MD11Financial disclosures / conflicts of interest: None.DOI: http://dx.doi.org/10.1016/j.amjoto.2016.07.007Article...
The safety of ICS and LABA during pregnancy, with no significant increased risk of gestational diabetes detected among users of these medications.
Article in PressThe Use of Asthma Controller Medications during Pregnancy and the Risk of Gestational DiabetesVéronique Baribeau, M.Sc (c), Marie-France Beauchesne, M.Sc. (Pharm.), Évelyne Rey, MD, Amélie Forget, M.Sc., Lucie Blais, Ph.D.Press enter key for correspondence informationPress enter key to...
Human circulating group 2 innate lymphoid cells can express CD154 and promote IgE production
Article in PressLaura Maggi, PhD, Gianni Montaini, BSc, Alessio Mazzoni, PhD, Beatrice Rossettini, BSc, Manuela Capone, PhD, Maria Caterina Rossi, PhD, Veronica Santarlasci, MD, Francesco Liotta, MD, Oliviero Rossi, MD, Oreste Gallo, MD, Raffaele De Palma, MD, Enrico Maggi, MD, Lorenzo Cosmi, MD, Sergio...
Histamine-secreting microbes
Article in PressHistamine-secreting microbes are increased in the gut of adult asthma patientsWeronika Barcik, MSca, Benoit Pugin, PhDa, Patrick Westermann, MSc, Noelia Rodriguez Perez, PhD,Ruth Ferstl, PhD, Marcin Wawrzyniak, PhD, Sylwia Smolinska, PhD, Marek Jutel, MD PhD, Edith Hessel, PhD, David...
Bacterial microbiota of the upper respiratory tract and childhood asthma
Article in PressMartin Depner, PhDPress enter key for correspondence informationPress enter key to Email the author, Markus J. Ege, MD, Michael J. Cox, PhD, Sarah Dwyer, PhD, Alan W. Walker, PhD, Lena T. Birzele, Jon Genuneit, MD, Elisabeth Horak, MD, Charlotte Braun-Fahrländer, MD, Hanna Danielewicz,...
Air pollutant mediated disruption of sinonasal epithelial cell barrier function is reversed by activation of the Nrf2 pathway
Article in PressNyall R. London Jr., M.D., Ph.D., Anuj Tharakan, B.S., Ana M. Rule, Ph.D., Andrew P. Lane, M.D., Shyam Biswal, Ph.D., Murugappan Ramanathan Jr., M.D.Press enter key for correspondence informationPress enter key to Email the authorDOI: http://dx.doi.org/10.1016/j.jaci.2016.06.027Article...
The decompression of large odontogenic cystic lesions
Article in PressNew method to secure cyst decompression tube in tooth-bearing areasF. Zhu, S. Huang, Z. Chen, W. Li, D. ZhangPress enter key for correspondence informationPress enter key to Email the authorDOI: http://dx.doi.org/10.1016/j.bjoms.2016.07.001Article InfoAbstractFull TextImagesReferencesThe...
Craniofacial, skeletal, cardiac, and renal abnormalities.Simpson–Golabi–Behmel syndrome (SGBS), also called Bulldog syndrome, Sara Agers syndrome, Golabi–Rosen syndrome, Simpson dysmorphia syndrome (SDYS) or X-linked dysplasia gigantism syndrome (DGSX)
https://ghr.nlm.nih.gov/condition/simpson-golabi-behmel-syndromeSimpson-Golabi-Behmel syndrome is a condition that affects many parts of the body and occurs primarily in males. This condition is classified as an overgrowth syndrome, which means that affected infants are considerably larger than normal...
Direct positioning splint to align a complex fracture of the zygoma
Article in PressButtress guide: P. BujtárPress enter key for correspondence informationPress enter key to Email the author, P. Steele, I. Holland, M. HalsnadDOI: http://dx.doi.org/10.1016/j.bjoms.2016.04.027Article InfoAbstractFull TextImagesReferencesAnterolateral projection of the middle third of the...
Tuberosity-alveolar block as a donor site for localised augmentation of the maxilla
Article in Press: a retrospective clinical studyArash KhojastehPress enter key for correspondence informationPress enter key to Email the author, Pantea Nazeman, Len TolstunovDOI: http://dx.doi.org/10.1016/j.bjoms.2016.06.018Article InfoAbstractFull TextImagesReferencesAbstractBone from the maxillary...
De-epithelialised radial forearm free flap to recontour the buccal commissure
Article in PressR. ElledgePress enter key for correspondence informationPress enter key to Email the author, M. Saggu1,Press enter key to Email the author, S. Parmar1,Press enter key to Email the author, T. Martin1,Press enter key to Email the author, P. Praveen1,Press enter key to Email the author1Tel:...
Orbitocranial wooden foreign body
Article in Press retrieved by transcranial and superior orbitotomyM.H. WilsonPress enter key for correspondence informationPress enter key to Email the author, T.R. Collins, P.J. RevingtonDepartment of Oral and Maxillofacial Surgery, University Hospitals Bristol, Upper Maudlin Street, Bristol, BS2 8HW,...
Evolution of the management of ranulas
Article in Press: change in a single surgeon's practice 2001-14A. HillsPress enter key for correspondence informationPress enter key to Email the author, A. HoldenPress enter key to Email the author, M. McGurk1,Press enter key to Email the author1Secretary: Tel.: +44 020 7188 4349.DOI: http://dx.doi.org/10.1016/j.bjoms.2016.07.005Article...
Primary leiomyosarcoma of the internal jugular vein with cervical extravascular extension
Article in PressRare M. Moreno-SánchezPress enter key for correspondence informationPress enter key to Email the author, R. González-García1, C. Moreno-García, W. Toro, F. Monje11International Member of the American Society of TMJ Surgeons (ASTMJS).DOI: http://dx.doi.org/10.1016/j.bjoms.2016.06.019Article...
99mTc MDP SPECT scintigraphy in the diagnosis of unilateral condylar hyperplasia
Evaluation of three analysis methods for 99mTc MDP SPECT scintigraphy in the diagnosis of unilateral condylar hyperplasia: The aims of the study were to evaluate the diagnostic accuracy and utility of the mean region of interest (ROI) and mean and maximum volume of interest (VOI) analysis methods for...
Use of deep laryngeal oxygen insufflation during laryngoscopy in children: a randomized clinical trial
Use of deep laryngeal oxygen insufflation during laryngoscopy in children: a randomized clinical trial: BackgroundBrief periods of haemoglobin oxygen desaturation are common in children during induction of general anaesthesia. We tested the hypothesis that oxygen insufflation during intubation slows...
HAE Pathophysiology and Underlying Mechanisms
HAE Pathophysiology and Underlying Mechanisms: AbstractRemarkable progress in understanding the pathophysiology and underlying mechanisms of hereditary angioedema has led to the development of effective treatment for this disorder. Progress in three separate areas has catalyzed our understanding of hereditary...
Chronic invasive fungal sinusitis
 characterization and shift in management of a rare disease: BackgroundChronic invasive fungal sinusitis (CIFS) is a rare subtype of mycotic diseases involving the paranasal sinuses. It is characterized by a slow onset and invasive organisms with non-granulomatous inflammation seen on histopathology....
The traction process in the treatment for Pierre-Robin Sequence
Article in PressNumerical modeling of Jakub J. Słowiński, Ph.D. (assistant professor)Press enter key for correspondence informationPress enter key to Email the author, Aleksandra Czarnecka, M.Sc.Department of Mechanics, Materials Science and Engineering; Faculty of Mechanical Engineering; Wroclaw University... 


Design, synthesis, and negative inotropic evaluation of 4-phenyl-1H-1,2,4-triazol-5(4H)-one derivatives containing triazole or piperazine moieties
Alexandros G. SfakianakisστοΘεραπείαΠριν από 3 δευτερόλεπτα
Abstract In the present study, four novel series of 4-phenyl-1*H*-1,2,4-triazol-5(4 *H*)-one derivatives containing triazole or piperazine moieties were designed, synthesized and evaluated for negative inotropic activity by measuring the left atrium stroke volume in isolated rabbit heart preparations. Almost all of the compounds showed an ability to moderate the cardiac workload by decreasing the heart rate and contractility. Among them, *7h* was found to be the most potent with a change in stroke volume of −48.22 ± 0.36% at a concentration of 3×10−5 mol/L (metoprolol: −9.74 ± 0.14... περισσότερα »

Discovery of neurotrophic agents based on hydroxycinnamic acid scaffold

Alexandros G. SfakianakisστοΘεραπείαΠριν από 3 δευτερόλεπτα
Abstract The number of people affected by neurodegenerative disorders such as Alzheimer's disease and Parkinson's disease is rapidly increasing owing to the global increase in life expectancy. Small molecules with neurotrophic effects have great potential for management of these neurological disorders. In this study, different (C1-C12) alkyl ester derivatives of hydroxycinnamic acids (HCAs) were synthesized (a total of 30 compounds). The neurotrophic capacity of the test compounds was examined by measuring promotion of survival in serum-deprived conditions and enhancement of nerve ... περισσότερα »

A prospective multicenter study to compare the precision of posttraumatic internal orbital reconstruction with standard preformed and individualized orbital implants

Alexandros G. SfakianakisστοOroFacial Medicine by Alexandros G.SfakianakisΠριν από 7 δευτερόλεπτα
Publication date: Available online 21 July 2016 *Source:*Journal of Cranio-Maxillofacial Surgery Author(s): Rüdiger M. Zimmerer, Edward Ellis, Gregorio Sanchez Aniceto, Alexander Schramm, Maximilian E.H. Wagner, Michael P. Grant, Carl-Peter Cornelius, Edward Bradley Strong, Majeed Rana, Lim Thiam Chye, Alvaro Rivero Calle, Frank Wilde, Daniel Perez, Frank Tavassol, Gido Bittermann, Nicholas R. Mahoney, Marta Redondo Alamillos, Joanna Bašić, Jan Dittmann, Michael Rasse, Nils-Claudius Gellrich PurposeA variety of implants are available for orbital reconstruction. Titanium orbital mesh... περισσότερα »

Visible Tumor Surface Response to Physical Plasma and Apoptotic Cell Kill in Head and Neck Cancer

Alexandros G. SfakianakisστοOroFacial Medicine by Alexandros G.SfakianakisΠριν από 7 δευτερόλεπτα
Publication date: Available online 18 July 2016 *Source:*Journal of Cranio-Maxillofacial Surgery Author(s): Matthias Schuster, Christian Seebauer, Rico Rutkowski, Anna Hauschild, Fred Podmelle, Camilla Metelmann, Bibiana Metelmann, Thomas von Woedtke, Sybille Hasse, Klaus-Dieter Weltmann, Hans-Robert Metelmann The aim of the study was to learn, whether clinical application of cold atmospheric pressure plasma (CAP) is able to cause (i) visible tumor surface effects and (ii) apoptotic cell kill in sqamous cell carcinoma and (iii) whether CAP-induced visible tumor surface response occur... περισσότερα »

Long-term (6.5 years) follow-up of mandibular midline distraction

Alexandros G. SfakianakisστοOroFacial Medicine by Alexandros G.SfakianakisΠριν από 7 δευτερόλεπτα
Publication date: Available online 14 July 2016 *Source:*Journal of Cranio-Maxillofacial Surgery Author(s): J.P. De Gijt, A. Gül, H. Sutedja, E.B. Wolvius, K.G.H. Van Der Wal, M.J. Koudstaal To assess the long-term stability and biomechanical effects of mandibular midline distraction (MMD), a prospective observational study was conducted with a retrospective cohort. Included were 17 MMD patients, of whom 9 completed the long-term follow-up with a mean of 6.5 years. In all patients a bone-borne distractor was used.Dental casts and posterior-anterior (PA) cephalograms were taken at fi... περισσότερα »

Increase of prevalence of craniosynostosis

Alexandros G. SfakianakisστοOroFacial Medicine by Alexandros G.SfakianakisΠριν από 7 δευτερόλεπτα
Publication date: Available online 12 July 2016 *Source:*Journal of Cranio-Maxillofacial Surgery Author(s): Martijn Cornelissen, Bianca den Ottelander, Dimitris Rizopoulos, René van der Hulst, Aebele Mink van der Molen, Chantal van der Horst, Hans Delye, Marie-Lise van Veelen, Gouke Bonsel, Irene Mathijssen IntroductionCraniosynostosis represents premature closure of cranial sutures. Prevalence is approximately 3.1-6.4 in 10.000 live births, which is reportedly rising. This epidemiologic study aims to provide insight into this rise through an accurate description of the prevalence, e... περισσότερα »

Patient-derived tumor xenograft models for melanoma drug discovery.

Alexandros G. SfakianakisστοΟγκολογίαΠριν από 8 δευτερόλεπτα
Related Articles *Patient-derived tumor xenograft models for melanoma drug discovery.* Expert Opin Drug Discov. 2016 Jul 25; Authors: Harris AL, Joseph RW, Copland JA Abstract INTRODUCTION: Cutaneous metastatic melanoma (MM) an aggressive form of skin cancer, with treatment providing cures to a minority of patients. The multiple risk factors that contribute to MM development suggest that cutaneous melanomas embody a repertoire of altered genetic events requiring studies to better understand its biology in order to develop novel therapies. AREAS COVERED: Patient-derived tumor xeno... περισσότερα »

Racial disparities in melanoma survival

Alexandros G. SfakianakisστοΟγκολογίαΠριν από 8 δευτερόλεπτα
Melanoma is a cutaneous malignancy common in the white population but can also occur in other racial groups. http://ift.tt/2adfATi

Sickle Cells Abolish Melanoma Tumorigenesis in Hemoglobin SS Knockin Mice and Augment the Tumoricidal Effect of Oncolytic Virus In Vivo.

Alexandros G. SfakianakisστοΟγκολογίαΠριν από 8 δευτερόλεπτα
Related Articles *Sickle Cells Abolish Melanoma Tumorigenesis in Hemoglobin SS Knockin Mice and Augment the Tumoricidal Effect of Oncolytic Virus In Vivo.* Front Oncol. 2016;6:166 Authors: Sun CW, Willmon C, Wu LC, Knopick P, Thoerner J, Vile R, Townes TM, Terman DS Abstract Insights from the study of cancer resistance in animals have led to the discovery of novel anticancer pathways and opened new venues for cancer prevention and treatment. Sickle cells (SSRBCs) from subjects with homozygous sickle cell anemia (SCA) have been shown to target hypoxic tumor niches, induce diffuse... περισσότερα »

Application of Vacuum-Assisted Closure Therapy and Hyperbaric Oxygen Therapy for an Exposed Titanium Plate After Mandible Reconstruction.

στοOtoRhinoLaryngology - Head and Neck SurgeryΠριν από 8 δευτερόλεπτα
The authors report a case of an 84-year-old woman with an exposed mandibular plate after reconstruction, which finally healed with combination therapy using vacuum-assisted closure therapy and hyperbaric oxygen therapy. The woman was diagnosed with mucosal carcinoma of the right oral cavity. During reconstruction after segmental excision of the mandible, a titanium plate was selected based on several risk factors. After the operation, the plate became exposed at the center of the chin. A second surgery was deemed inappropriate because of her age, malnutrition, and recurrent aspira... περισσότερα »

Treatment of Large Thyroglossal Duct Cyst.

στοOtoRhinoLaryngology - Head and Neck SurgeryΠριν από 8 δευτερόλεπτα
The thyroglossal duct cyst is the neck congenital abnormality most common in the childhood. Clinically, it shows itself as a solitary neck mass in the region of hyoid bone, it is painless and can be dislocated during de physical examination and tongue protrusion. The most common treatment is its removal through the Sistrunk technique. Patient with diagnosis of thyroglossal duct cyst in neck region with extension to the mouth floor was treated by total surgical removal through intraoral access. The intraoral approach to the treatment of the thyroglossal duct cyst showed itself prac... περισσότερα »

Pedunculated Primary Mucosal Malignant Melanoma Originated From the Posterior Nasal Septum.

στοOtoRhinoLaryngology - Head and Neck SurgeryΠριν από 8 δευτερόλεπτα
Primary mucosal malignant melanoma of the nasal cavity is a rare disease. The authors present the patient of a pedunculated primary mucosal malignant melanoma originated from the posterior nasal septum, which was successfully removed via the endoscopic approach. Clinicians should consider the possibility that a primary mucosal malignant melanoma may originate in the nasal cavity, mimicking the other more frequently observed lesions. © 2016 by Mutaz B. Habal, MD. http://ift.tt/2azDc68

Safety of Outpatient Isolated Orbital Floor Fracture Repair.

στοOtoRhinoLaryngology - Head and Neck SurgeryΠριν από 8 δευτερόλεπτα
Orbital fractures are common, accounting for nearly 40% of all facial fractures. Open repair is required to restore preinjury orbital volume and relieve any extra-ocular muscle entrapment. Monitoring for postoperative intraorbital hemorrhage, and its consequent potential for visual impairment, has triggered most surgeons to observe their patients in the hospital overnight postoperatively. The real risk of postoperative hemorrhage in this patient group, however, is uncertain and the need to contain healthcare costs clear. The objective of this study was thus to determine the incide... περισσότερα »

Idiopathic Orbital Inflammatory Pseudotumor With Bone Erosion.

στοOtoRhinoLaryngology - Head and Neck SurgeryΠριν από 8 δευτερόλεπτα
Purpose/Background: To report a rare patient with idiopathic orbital inflammatory pseudotumor showing obvious bone erosion of the orbital wall. Methods: Clinical features and imaging findings, orbital surgery, and histopathological examination are presented. Results: A 56-year-old Chinese man showed a gradually growing unilateral proptosis of the left eye for 6 months. Visual acuity, intraocular pressure, anterior segment, and fundi were normal in both eyes. Proptosis was 17 mm in the right eye and 23 mm in the left. No palpable mass was present on the left orbital rim. Ocular mot... περισσότερα »

Zigzag Temporal Incision With Preauricular Incision Extension as a Variant Approach to the Temporomandibular Joint.

στοOtoRhinoLaryngology - Head and Neck SurgeryΠριν από 8 δευτερόλεπτα
Surgical visibility of the joint is often compromised by the efforts to protect the facial nerve and its branches. Several approaches to the temporomandibular joint have been proposed over the years and perhaps the standard and most commonly used incision is the preauricular which is then extended with coronal incision to improve visibility and safety during surgery. The authors present a new modification based on the achievement of an aesthetically acceptable and inconspicuous scar in the temporal area. This is achieved by using a preauricular incision extended with a zigzag inci... περισσότερα »

Pneumocephalus Following Air Travel in a Patient With Preexisting Facial Fractures and Dural Tears.

στοOtoRhinoLaryngology - Head and Neck SurgeryΠριν από 8 δευτερόλεπτα
Changes in cabin pressure can potentially cause expansion of any preexisting intracranial air resulting in tension pneumocephalus. The authors describe a 28-year-old man, who was involved in a motor vehicle accident complicated by multiple facial fractures and a dural tear while on his way to the airport. Instead of seeking medical attention after the accident, he proceeded with a 2-hour commercial flight. He did not suffer from any neurologic deterioration inflight, but upon presentation to our center, a computed tomography scan was done which revealed extensive pneumocephalus, f... περισσότερα »

Bone Healing Promotion by Negatively Charged Polysterene Microspheres.

στοOtoRhinoLaryngology - Head and Neck SurgeryΠριν από 8 δευτερόλεπτα
Bone healing under optimal conditions is fairly predictable. Yet when the healing process is disturbed by inadequate immobilization, inadequate blood supply, or scar tissue, little therapeutic alternatives to surgery exist. It appears that redistribution of electric charges along the bone during a callus consolidation promotes bone healing. It has been shown in the past that negatively charged polysterene spheres promote bone growth in animal models. In this preliminary report, we tested weather or not a commercial device of negatively charged polysterene spheres promotes bone heal... περισσότερα »

Galeal Lip Augmentation: The Pancake Technique.

στοOtoRhinoLaryngology - Head and Neck SurgeryΠριν από 8 δευτερόλεπτα
No abstract available http://ift.tt/2azDSbk

Review of "Impact of Hospital Characteristics on Failure to Rescue Following Major Surgery" by Sheetz K, Dimick JB, Ghaferi AA in Ann Surg 263: 692-697, 2016.

στοOtoRhinoLaryngology - Head and Neck SurgeryΠριν από 8 δευτερόλεπτα
No abstract available http://ift.tt/2azDqdg

Plasma Fibrinogen in Patients With Bell Palsy.

στοOtoRhinoLaryngology - Head and Neck SurgeryΠριν από 8 δευτερόλεπτα
Objective: To determine the plasma fibrinogen level in patients with Bell palsy and explore the significances of it in Bell palsy. Methods: One hundred five consecutive patients with facial paralysis were divided into 3 groups: group I (Bell palsy), group II (temporal bone fractures), and group III (facial nerve schwannoma). In addition, 22 volunteers were defined as control group. Two milliliters fasting venous blood from elbow was collected, and was evaluated by CA-7000 Full-Automatic Coagulation Analyzer. Results: The plasma fibrinogen concentration was significantly higher in ... περισσότερα » 
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