Unilateral Resection of the Anterior Medial Temporal Lobe Impairs Odor Identification and Valence Perception.
Unilateral Resection of the Anterior Medial Temporal Lobe Impairs Odor Identification and Valence Perception.: *Unilateral Resection of the Anterior Medial Temporal Lobe Impairs Odor Identification and Valence Perception.* Front Psychol. 2015;6:2015 Authors: Juran SA, Lundström JN, Geigant M, Kumlien E, Fredrikson M, Åhs F, Olsson MJ Abstract The anterior medial temporal lobe (TL), including the amygdala, has been implicated in olfactory processing, e.g., coding for intensity and valence, and seems also involved in memory. With this background, the present study evaluated whethe...περισσότερα »
Pathophysiology of central sleep apneas : The fundamental hallmark of central sleep apnea (CSA) disorders is the presence of ventilatory control instability
Pathophysiology of central sleep apneas: AbstractThe transition from wake to sleep is accompanied by a host of physiologic changes, which result in major alterations in respiratory control and may result in sleep-related breathing disorders. The central sleep apneas are a group of sleep-related breathing disorders that are characterized by recurrent episodes of airflow reduction or cessation due to a temporary reduction or absence of central respiratory drive. The fundamental hallmark of central sleep apnea (CSA) disorders is the presence of ventilatory control instability; however...περισσότερα »
Revista de Logopedia, Foniatría y Audiología
Validez y confiabilidad de una prueba para evaluar comportamientos lingüísticos en población con discapacidad cognitiva Publication date: Available online 19 January 2016 *Source:*Revista de Logopedia, Foniatría y Audiología Author(s): Adriana Marcela Rojas Gil, Ricardo León Sánchez Arenas El lenguaje se constituye en una variable importante en el desarrollo de la habilidad comunicativa de todo ser humano; su desarrollo depende, entre otros aspectos, de las oportunidades dadas por el contexto. Dentro de estas oportunidades, se encuentran los servicios de fonoaudiología, en donde los ... περισσότερα »
Sulfhydryl-mediated redox signaling in inflammation: role in neurodegenerative diseases.
Commentary to Gorelenkova Miller and Mieyal (2015): sulfhydryl-mediated redox signaling in inflammation: role in neurodegenerative diseases.: *Commentary to Gorelenkova Miller and Mieyal (2015): sulfhydryl-mediated redox signaling in inflammation: role in neurodegenerative diseases.* Arch Toxicol. 2016 Jan 16; Authors: Kato M, Ninomiya H, Maeda M, Tanaka N, Ilmiawati C, Yoshinaga M Abstract Gorelenkova Miller and Mieyal (Arch Toxicol 89(9): 1439-1467, 2015) recently published a review paper suggesting that reversible cysteine plays a key role in redox-linked signal transduction vi...περισσότερα »
Effects of relative and absolute frequency in the spectral weighting of loudness
Effects of relative and absolute frequency in the spectral weighting of loudnessa): The loudness of broadband sound is often modeled as a linear sum of specific loudness across frequency bands. In contrast, recent studies using molecular psychophysical methods suggest that low and high frequency components contribute more to the overall loudness than mid frequencies. In a series of experiments, the contribution of individual components to the overall loudness of a tone complex was assessed using the molecular psychophysical method as well as a loudness matching task. The stimuli we...περισσότερα »
An acoustic study of multiple lateral consonants
An acoustic study of multiple lateral consonants in three Central Australian languages: This study presents dental, alveolar, retroflex, and palatal lateral /̪ll ɭ ʎ/ data from three Central Australian languages: Arrernte, Pitjantjatjara, and Warlpiri. Formant results show that the laminal laterals (dental /̪l/ and palatal /ʎ/) have a relatively low F1, presumably due to a high jaw position for these sounds, as well as higher F4. In addition, the palatal /ʎ/ has very high F2. There is relatively little difference in F3 between the four lateral places of articulation. However, the r... περισσότερα »
Investigation of the effect of the efficiency of noise at different intensities on the DNA of the newborns
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 5 δευτερόλεπτα
Investigation of the effect of the efficiency of noise at different intensities on the DNA of the newborns: Nesrin Ceylan, Sultan Kaba, Kamuran Karaman, Metin Celiker, Yildiray Basbugan, Nihat Demir Noise and Health 2016 18(80):7-9 Hearing loss can occur in newborns exposed to high-level noise; noise exposure can cause more physiological stress and can lead […]
Evaluation of the effects of occupational noise exposure on serum aldosterone and potassium among industrial workers
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 5 δευτερόλεπτα
Evaluation of the effects of occupational noise exposure on serum aldosterone and potassium among industrial workers: Sajad Zare, Parvin Nassiri, Mohammad Reza Monazzam, Akram Pourbakht, Kamal Azam, Taghi Golmohammadi Noise and Health 2016 18(80):1-6 The existing literature indicates that occupational exposure to noise may have adverse effects on workers’ health. The aim of this study […]
Relative Weighting of Semantic and Syntactic Cues in Native and Non-Native Listeners’ Recognition of English Sentences.
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 5 δευτερόλεπτα
Relative Weighting of Semantic and Syntactic Cues in Native and Non-Native Listeners’ Recognition of English Sentences.: Objective: Non-native listeners do not recognize English sentences as effectively as native listeners, especially in noise. It is not entirely clear to what extent such group differences arise from differences in relative weight of semantic versus syntactic cues. This […]
Masked Speech Perception Thresholds in Infants, Children, and Adults.
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 5 δευτερόλεπτα
Masked Speech Perception Thresholds in Infants, Children, and Adults.: Objective: The primary goal of this study was to compare infants’ susceptibility to making produced by a two-talker speech and a speech-shaped noise masker. It is well documented that school-age children experience more difficulty recognizing speech embedded in two-talker speech than spectrally matched noise, a result […]
Relevance of Helicobacter pylori vacA 3ʹ-end Region Polymorphism to Gastric Cancer
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 5 δευτερόλεπτα
Relevance of Helicobacter pylori vacA 3ʹ-end Region Polymorphism to Gastric Cancer: Abstract Background Helicobacter pylori vacA genotypes play an important role in the pathogenesis of severe gastrointestinal disease. Materials and Methods We identified a novel polymorphic site in the 3ʹ-end region of H. pylori vacA gene, denoted by c1/-c2 (c1: with deletion of 15 bp), […]
H. pylori infection is negatively associated with children’s growth. Chronic inflammation of the stomach that results in the loss of appetite and, dysregulation of neuroendocrine hormones
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 5 δευτερόλεπτα
Helicobacter pylori Infection in Children: Nutritional Status and Associations with Serum Leptin, Ghrelin, and IGF-1 Levels: Abstract Background Helicobacter pylori is associated with gastrointestinal diseases such as gastritis, peptic ulcers, malignancy and lymphoma, and extra-gastrointestinal conditions. H. pylori infection is negatively associated with children’s growth. Chronic inflammation of the stomach that results in the loss […]
Helicobacter pylori Infection in Children: Nutritional Status and Associations with Serum Leptin, Ghrelin, and IGF-1 Levels
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 5 δευτερόλεπτα
Helicobacter pylori Infection in Children: Nutritional Status and Associations with Serum Leptin, Ghrelin, and IGF-1 Levels: Abstract Background Helicobacter pylori is associated with gastrointestinal diseases such as gastritis, peptic ulcers, malignancy and lymphoma, and extra-gastrointestinal conditions. H. pylori infection is negatively associated with children’s growth. Chronic inflammation of the stomach that results in the loss […]
The Changing Profile of Helicobacter pylori Antibiotic Resistance
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 5 δευτερόλεπτα
The Changing Profile of Helicobacter pylori Antibiotic Resistance in Singapore: A 15-Year Study: Abstract Background Antibiotic resistance is an important cause of H. pylori treatment failure. This study aimed to examine the change in H. pylori antibiotic resistance profile in Singapore over the course of 15 years. Materials and methods The study period was from […]
Ruxolitinib induces interleukin-17 and ameliorates chronic mucocutaneous candidiasis caused by STAT1 gain-of-function mutation
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 5 δευτερόλεπτα
from #Infections via alexandrossfakianakis on Inoreader http://ift.tt/1S3mv2p via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/23dNzBg via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1ltTxvz via IFTTT
Digital Evaluation of Orbital Development after Self-inflating Hydrogel Expansion in Chinese Children with Congenital Microphthalmia
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 5 δευτερόλεπτα
Publication date: Available online 19 January 2016 Source:Journal of Plastic, Reconstructive & Aesthetic Surgery Author(s): Zhijia Hou, Junfang Xian, Qinglin Chang, Wenbin Wei, Dongmei Li BackgroundAssessment of the growth of bony orbit in children with blind microphthalmia is essential to the management. In this study variables were measured to evaluate the development of the bony […]
Modeling of aerodynamic interaction between vocal folds and vocal tract during production of a vowel–voiceless plosive–vowel sequence
Modeling of aerodynamic interaction between vocal folds and vocal tract during production of a vowel–voiceless plosive–vowel sequence: The context of this study is the physical modeling of speech production. The objective is, by using a mechanical replica of the vocal tract, to test quantitatively an aerodynamic model of the interaction between the vocal folds and the vocal tract during the production of a vowel–voiceless plosive–vowelsequence. The first step is to realize acoustic and aerodynamic measurements on a speaker during the production of an /apa/ sequence. The aperture an... περισσότερα »
Evaluating effectiveness of dynamic soundfield system in the classroom
Evaluating effectiveness of dynamic soundfield system in the classroom: *Aline Duarte da Cruz, Kelly Cristina Alves Silvério, Aline Roberta Aceituno Da Costa, Adriane Lima Mortari Moret, José Roberto Pereira Lauris, Regina Tangerino de Souza Jacob* Noise and Health 2016 18(80):42-49 Research has reported on the use of soundfield amplification devices in the classroom. However, no study has used standardized tests to determine the potential advantages of the dynamic soundfield system for normally hearing students and for the teacher's voice. Our aim was to evaluate the impact of ... περισσότερα »
Age-related hearing decline in individuals with and without occupational noise exposure
Age-related hearing decline in individuals with and without occupational noise exposure: *Christina Hederstierna, Ulf Rosenhall* Noise and Health 2016 18(80):21-25 This study was conducted to compare the pattern of age-related hearing decline in individuals with and without self-reported previous occupational noise exposure. This was a prospective, population-based, longitudinal study of individuals aged 70-75 years, from an epidemiological investigation, comprising three age cohorts. In total there were 1013 subjects (432 men and 581 women). Participants were tested with pure t...περισσότερα »
Acoustic assessment of speech privacy curtains in two nursing units
Acoustic assessment of speech privacy curtains in two nursing units: *Diana S Pope, Erik T Miller-Klein* Noise and Health 2016 18(80):26-35 Hospitals have complex soundscapes that create challenges to patient care. Extraneous noise and high reverberation rates impair speech intelligibility, which leads to raised voices. In an unintended spiral, the increasing noise may result in diminished speech privacy, as people speak loudly to be heard over the din. The products available to improve hospital soundscapes include construction materials that absorb sound (acoustic ceiling tile... περισσότερα »
Distortion product otoacoustic emissions in college music majors and nonmusic majors
Distortion product otoacoustic emissions in college music majors and nonmusic majors: *Rebecca L. Warner Henning, Kate Bobholz* Noise and Health 2016 18(80):10-20 The presence and absence of distortion product otoacoustic emissions (DPOAEs) as well as DPOAE amplitudes were compared between college music majors and a control group of nonmusic majors. Participants included 28 music majors and 35 nonmusic majors enrolled at a university with ages ranging from 18-25 years. DPOAEs and hearing thresholds were measured bilaterally on all the participants. DPOAE amplitudes were analyzed... περισσότερα »
Preferred listening levels of mobile phone programs when considering subway interior noise
Preferred listening levels of mobile phone programs when considering subway interior noise: *Jyaehyoung Yu, Donguk Lee, Woojae Han* Noise and Health 2016 18(80):36-41 Today, people listen to music loud using personal listening devices. Although a majority of studies have reported that the high volume played on these listening devices produces a latent risk of hearing problems, there is a lack of studies on "double noise exposures" such as environmental noise plus recreational noise. The present study measures the preferred listening levels of a mobile phone program with subway i... περισσότερα »
Investigation of the effect of the efficiency of noise at different intensities on the DNA of the newborns
Investigation of the effect of the efficiency of noise at different intensities on the DNA of the newborns: *Nesrin Ceylan, Sultan Kaba, Kamuran Karaman, Metin Celiker, Yildiray Basbugan, Nihat Demir* Noise and Health 2016 18(80):7-9 Hearing loss can occur in newborns exposed to high-level noise; noise exposure can cause more physiological stress and can lead to DNA damage. This study was designed to determine DNA damage in newborn rats exposed to sound at different concentrations. For this purpose, 28 newborn (3-6 days old) rats were divided into four groups of 7 rats in each g...περισσότερα »
Evaluation of the effects of occupational noise exposure on serum aldosterone and potassium among industrial workers
Evaluation of the effects of occupational noise exposure on serum aldosterone and potassium among industrial workers: *Sajad Zare, Parvin Nassiri, Mohammad Reza Monazzam, Akram Pourbakht, Kamal Azam, Taghi Golmohammadi* Noise and Health 2016 18(80):1-6 The existing literature indicates that occupational exposure to noise may have adverse effects on workers' health. The aim of this study was to evaluate the possible effects of exposure to different sound pressure levels (SPLs) on serum aldosterone and potassium concentration among Iranian blue collar workers in Golgohar Mining a...περισσότερα »
Relative Weighting of Semantic and Syntactic Cues in Native and Non-Native Listeners' Recognition of English Sentences.
Relative Weighting of Semantic and Syntactic Cues in Native and Non-Native Listeners' Recognition of English Sentences.: Objective: Non-native listeners do not recognize English sentences as effectively as native listeners, especially in noise. It is not entirely clear to what extent such group differences arise from differences in relative weight of semantic versus syntactic cues. This study quantified the use and weighting of these contextual cues via Boothroyd and Nittrouer's j and k factors. The j represents the probability of recognizing sentences with or without context, where... περισσότερα »
Masked Speech Perception Thresholds in Infants, Children, and Adults.
Masked Speech Perception Thresholds in Infants, Children, and Adults.: Objective: The primary goal of this study was to compare infants' susceptibility to making produced by a two-talker speech and a speech-shaped noise masker. It is well documented that school-age children experience more difficulty recognizing speech embedded in two-talker speech than spectrally matched noise, a result attributed to immaturity in the ability to segregate target from masker speech, and/or to selectively attend to the target while disregarding the perceptually similar speech masker. However, findings... περισσότερα »
Relevance of Helicobacter pylori vacA 3ʹ-end Region Polymorphism to Gastric Cancer
Relevance of Helicobacter pylori vacA 3ʹ-end Region Polymorphism to Gastric Cancer: Abstract Background *Helicobacter pylori vacA* genotypes play an important role in the pathogenesis of severe gastrointestinal disease. Materials and Methods We identified a novel polymorphic site in the 3ʹ-end region of *H. pylori vacA* gene, denoted by c1/-c2 (c1: with deletion of 15 bp), and examined associations of this and the previous four sites as well as *cagA* status with gastroduodenal diseases, in a total of 217 Iranian *H. pylori* isolates. Histopathologic evaluations were performed and p... περισσότερα »
H. pylori infection is negatively associated with children's growth. Chronic inflammation of the stomach that results in the loss of appetite and, dysregulation of neuroendocrine hormones
Helicobacter pylori Infection in Children: Nutritional Status and Associations with Serum Leptin, Ghrelin, and IGF-1 Levels: Abstract Background *Helicobacter pylori* is associated with gastrointestinal diseases such as gastritis, peptic ulcers, malignancy and lymphoma, and extra-gastrointestinal conditions. *H. pylori* infection is negatively associated with children's growth. Chronic inflammation of the stomach that results in the loss of appetite and, dysregulation of neuroendocrine hormones such as leptin, and ghrelin are the probable reasons of this negative association. The o...περισσότερα »
Helicobacter pylori Infection in Children: Nutritional Status and Associations with Serum Leptin, Ghrelin, and IGF-1 Levels
Helicobacter pylori Infection in Children: Nutritional Status and Associations with Serum Leptin, Ghrelin, and IGF-1 Levels: Abstract Background *Helicobacter pylori* is associated with gastrointestinal diseases such as gastritis, peptic ulcers, malignancy and lymphoma, and extra-gastrointestinal conditions. *H. pylori* infection is negatively associated with children's growth. Chronic inflammation of the stomach that results in the loss of appetite and, dysregulation of neuroendocrine hormones such as leptin, and ghrelin are the probable reasons of this negative association. The o...περισσότερα »
The Changing Profile of Helicobacter pylori Antibiotic Resistance
The Changing Profile of Helicobacter pylori Antibiotic Resistance in Singapore: A 15-Year Study: Abstract Background Antibiotic resistance is an important cause of *H. pylori* treatment failure. This study aimed to examine the change in *H. pylori* antibiotic resistance profile in Singapore over the course of 15 years. Materials and methods The study period was from 2000 to 2014. Gastric mucosal biopsies obtained from *H. pylori*-positive patients were cultured. Antibiotic susceptibility to metronidazole, clarithromycin, levofloxacin, tetracycline, and amoxicillin was tested. The ch... περισσότερα »
Alternative splicing in buccal mucosa squamous cell carcinoma
The landscape of alternative splicing in buccal mucosa squamous cell carcinoma via ScienceDirect Search: ESOPHAGEAL CANCER *Source:*Oral Oncology, Volume 49, Issue 6 Author(s): Tejas M. Shah, Amrutlal K. Patel, Vaibhav D. Bhatt, Ajai K. Tripathi, Siddharth Shah, Vangipuram Shankar, Chaitanya G. Joshi ObjectivesAlternative splicing (AS) is a key regulatory mechanism in the process of protein synthesis generating transcriptome and proteome diversity. In this study, we attempted to identify alternative splicing in a pair of BMSCC cancer and adjacent normal tissue using RNAseq datasets an...περισσότερα »
p27 and BCL2 expression predicts response to chemotherapy in head and neck squamous cell carcinomas
p27 and BCL2 expression predicts response to chemotherapy in head and neck squamous cell carcinomas via ScienceDirect Search: ESOPHAGEAL CANCER Publication date: February 2014 *Source:*Oral Oncology, Volume 50, Issue 2 Author(s): Carla Moreno-Galindo, Mario Hermsen, Juana M. García-Pedrero, Manuel F. Fresno, Carlos Suárez, Juan P. Rodrigo ObjectivesHead and neck squamous cell carcinomas (HNSCCs) are characterized by marked heterogeneity in their biological behavior and response to treatment. Our goal was the identification of biomarkers that can be used to predict response to chemother... περισσότερα »
Cause-specific excess mortality in patients treated for cancer of the oral cavity and oropharynx
Cause-specific excess mortality in patients treated for cancer of the oral cavity and oropharynx: A population-based study Publication date: January 2016 *Source:*Oral Oncology, Volume 52 Author(s): H.S. van Monsjou, M. Schaapveld, O. Hamming-Vrieze, J.P. de Boer, M.W.M. van den Brekel, A.J.M. Balm Purpose To assess cause-specific mortality in a large population-based cohort of 14,393 patients treated for squamous cell carcinoma of the oral cavity (OC) or oropharynx (OP) in The Netherlands between 1989 and 2006.Patients and methods Causes of death were obtained for 94.7% of 9620 pa...περισσότερα »
DNA methylation markers for oral pre-cancer progression
: A critical review Publication date: February 2016 *Source:*Oral Oncology, Volume 53 Author(s): Krithiga Shridhar, Gagandeep Kaur Walia, Aastha Aggarwal, Smriti Gulati, A.V. Geetha, Dorairaj Prabhakaran, Preet K. Dhillon, Preetha Rajaraman Although oral cancers are generally preceded by a well-established pre-cancerous stage, there is a lack of well-defined clinical and morphological criteria to detect and signal progression from pre-cancer to malignant tumours. We conducted a critical review to summarize the evidence regarding aberrant DNA methylation patterns as a potential diagn... περισσότερα »
Oral Oncology
Editorial Board/Aims & Scope Publication date: February 2016 *Source:*Oral Oncology, Volume 53 DNA methylation markers for oral pre-cancer progression: A critical review Publication date: February 2016 *Source:*Oral Oncology, Volume 53 Author(s): Krithiga Shridhar, Gagandeep Kaur Walia, Aastha Aggarwal, Smriti Gulati, A.V. Geetha, Dorairaj Prabhakaran, Preet K. Dhillon, Preetha Rajaraman Although oral cancers are generally preceded by a well-established pre-cancerous stage, there is a lack of well-defined clinical and morphological criteria to detect and signal progression fr... περισσότερα »
Is p16-positive oropharyngeal squamous cell carcinoma associated with favorable prognosis?
A systematic review and meta-analysis via ScienceDirect Publication: Oral Oncology Publication date: Available online 18 January 2016 *Source:*Oral Oncology Author(s): Parish P. Sedghizadeh, William D. Billington, Dain Paxton, Rabeh Ebeed, Susan Mahabady, Glenn T. Clark, Reyes Enciso The purpose of this systematic review and meta-analysis was to compare the prognosis of patients with p16 expressing oropharyngeal squamous cell cancers to patients with p16 non-expressing cancers. Clinical outcomes that were evaluated included overall survival, local recurrence, disease-free survival, di...περισσότερα »
Comparison of Subcutaneous versus Submuscular Expander Placement in the First Stage of Immediate Breast Reconstruction
Tissue expander based two-stage reconstruction remains the most commonly used technique in immediate breast reconstruction. This study compares the subcutaneous expander placement to the traditional submuscular placement and describes our early experience with the expander insertion plane choosing algorithm. from #Aesthetics via alexandrossfakianakis on Inoreader http://ift.tt/1ZLzyvm via IFTTT
Systematic review of the effectiveness of polyurethane-coated compared with textured silicone implants in breast surgery
Silicone gel implants are used worldwide for breast augmentation and breast reconstruction. Textured silicone implants are the most commonly placed implant, but increasingly, polyurethane-coated implants are used in an attempt to ameliorate the long-term complications associated with implant insertion. from #Aesthetics via alexandrossfakianakis on Inoreader http://ift.tt/1WsYbHL via IFTTT
Induction chemotherapy for oropharyngeal squamous cell carcinoma
Comparative effectiveness of induction chemotherapy for oropharyngeal squamous cell carcinoma: A population-based analysis via ScienceDirect Publication: Oral Oncology Publication date: Available online 18 January 2016 *Source:*Oral Oncology Author(s): David J. Sher, David L. Schwartz, Lucien Nedzi, Saad Khan, Randall Hughes, Mary Jo Fidler, Matthew Koshy ObjectivesDespite several randomized trials, the optimal chemotherapy paradigm for locally advanced oropharyngeal carcinoma (OPSCC) is controversial. This population-based analysis assessed the overall survival (OS) benefit of inducti...περισσότερα »
Inferior Turbinate Size and CPAP Titration Based Treatment Pressures: No Association Found among Patients Who Have Not Had Nasal Surgery
Inferior Turbinate Size and CPAP Titration Based Treatment Pressures: No Association Found among Patients Who Have Not Had Nasal Surgery: Objective. To evaluate the effect of turbinate sizes on the titrated continuous positive airway pressure (CPAP) therapeutic treatment pressures for patients with obstructive sleep apnea (OSA) who have not had nasal surgery. Study Design. Retrospective case series. Methods. A chart review was performed for 250 consecutive patients. Results. 45 patients met inclusion criteria. The mean ± standard deviation (M ± SD) for age was years and for body mas...περισσότερα »
Garnett Passe and the tonsillectomy gag
Review ArticleGarnett Passe and the tonsillectomy gagJ C Rice Emeritus Surgeon, Women’s and Children’s Hospital, Adelaide, Australia (formerly The Adelaide Children’s Hospital) Abstract Kevin Kane has written about the painting by Barbara Hepworth of Garnett Passe performing a tonsillectomy, and wondered about the way in which the gag appears to be suspended. This article traces historically the various methods of holding the gag for tonsillectomy, and postulates that what is illustrated in the Hepworth painting is a jack owned by the late Dr Sydney Cocks, who not only was a friend o... περισσότερα »
Initial assessment of hearing loss using a mobile application for audiological evaluation
Main ArticleInitial assessment of hearing loss using a mobile application for audiological evaluationS Derina1 c1, O H Cama2, H Beydillia3, E Acara3, S S Elicoraa4 and M Sahana1 a1 Department of Otolaryngology, School of Medicine, Mugla Sitki Kocman University, Mugla, Turkey a2 Department of Otolaryngology, Ozel Kucukyalı Delta Hospital, Istanbul, Turkey a3 Department of Emergency Medicine, School of Medicine, Mugla Sitki Kocman University, Mugla, Turkey a4 Department of Otolaryngology, School of Medicine, Bülent Ecevit University, Zonguldak, Turkey Abstract Objective: This study aime... περισσότερα »
Sublingual immunotherapy in patients with house dust mite allergic rhinitis: prospective study of clinical outcomes over a two-year period
Main ArticleSublingual immunotherapy in patients with house dust mite allergic rhinitis: prospective study of clinical outcomes over a two-year periodJ Y Soha1, M Thalayasingama2, S Onga3, E X L Looa4, L P Sheka1 c1 and S S Chaoa3 a1 University Children's Medical Institute, National University Health Systems, Singapore a2 Department of Paediatrics, International Medical University Clinical School, Seremban, Malaysia a3 Department of Otolaryngology Head and Neck Surgery, National University Health Systems, Singapore a4 Singapore Institute for Clinical Sciences, Agency for Science, Tec... περισσότερα »
Epistaxis management: current understanding amongst junior doctors
Main ArticleEpistaxis management: current understanding amongst junior doctorsR Foxa1 c1, R Nasha1, Z-W Liua1 and A Singha1 a1 ENT Department, Northwick Park Hospital, Harrow, UK Abstract Background: Epistaxis is a common and potentially life-threatening emergency. This survey assesses understanding and confidence in epistaxis management amongst current junior doctors. Method: A cross-sectional study was conducted of foundation year one and two doctors based at three National Health Service trusts within a single region of the UK, assessing basic understanding and procedural confidence... περισσότερα »
Human Papillomavirus 16 Physical Status and the TP53 Codon 72 Polymorphism in Japanese HPV-Positive Oropharyngeal Cancer Patients
Human Papillomavirus 16 Physical Status and the TP53 Codon 72 Polymorphism in Japanese HPV-Positive Oropharyngeal Cancer Patients: *Background:* In human papillomavirus (HPV)-induced carcinogenesis, the arginine (Arg) allele of the *TP53* codon 72 polymorphism binds more efficiently to the HPV E6 oncoprotein than the proline (Pro) allele. We investigated the physical status of HPV-16 DNA and the *TP53* codon 72 polymorphism in oropharyngeal squamous cell carcinoma (OPSCC). *Methods:* Tumor samples from 70 p16-positive OPSCC patients were tested for HPV-16 physical status by examinin... περισσότερα »
Radiotherapy With Cisplatin vs. Docetaxel-cetuximab in HNSCC: ERCC1 Biomarker Enrichment and Interaction Design
Radiotherapy With Cisplatin vs. Docetaxel-cetuximab in HNSCC: ERCC1 Biomarker Enrichment and Interaction Design: *Condition*: Squamous Cell Carcinoma *Interventions*: Drug: Cisplatin; Radiation: IMRT; Drug: Docetaxel; Drug: Cetuximab *Sponsor*: University of Pittsburgh The goal of this clinical research study is to learn which chemotherapy combination may be more effective in treating locally advanced head and neck squamous cell carcinoma (HNSCC). The side effects of these combinations will also be studied. This study treatment consists of intensity-modulated radiatio... περισσότερα »
Ficlatuzumab and Cetuximab in Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma (HNSCC)
Ficlatuzumab and Cetuximab in Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma (HNSCC): *Conditions*: Carcinoma, Squamous Cell of Head and Neck; Squamous Cell Carcinoma of the Head and Neck; Squamous Cell Carcinoma, Head And Neck *Interventions*: Drug: Ficlatuzumab; Drug: Cetuximab *Sponsors*: Julie E. Bauman, MD, MPH; AVEO Pharmaceuticals, Inc. The epidermal growth factor receptor (EGFR) is both oncogene and prognostic biomarker in head and neck squamous cell carcinoma (HNSCC). EGFR's functional importance in HNSCC resulted in development of the first mo... περισσότερα »
Regorafenib as Second or Third Line Therapy in Metastatic Medullary Thyroid Cancer
A Study Using Regorafenib as Second or Third Line Therapy in Metastatic Medullary Thyroid Cancer: *Condition*: Thyroid Cancer *Intervention*: Drug: Regorafenib *Sponsors*: Dana-Farber Cancer Institute; Bayer ArmsAssigned InterventionsExperimental: Regorafenib Regorafenib tablets orally, once daily at predetermined dosage for 21 days per cycle Drug: Regorafenib Regorafenib is a small molecule inhibitor of multiple membrane-bound and intracellular kinases involved in normal cellular functions and in pathologic processes. Other Name: Stivarga Detailed Description: This is a p... περισσότερα »
Head and Neck Cancer Treatment Related Dysphagia
Head and Neck Cancer Treatment Related Dysphagia: *Conditions*: Head and Neck Cancer; Dysphagia *Interventions*: Other: non- head and neck self reporting; Other: head neck self reporting; Other: provider reporting *Sponsor*: Sidney Kimmel Comprehensive Cancer Center Cancers located in the upper aerodigestive tract of the head and neck region present unique management challenges due to the crucial functions in this anatomic region along with its anatomic density. As such, cancers themselves and the actual treatment can affect these functions. Of these, the ability to e... περισσότερα »
Durvalumab and Tremelimumab in Combination With First-Line Chemotherapy in Advanced Solid Tumors
Durvalumab and Tremelimumab in Combination With First-Line Chemotherapy in Advanced Solid Tumors: *Conditions*: Small Cell Lung Carcinoma; Carcinoma, Squamous Cell of Head and Neck; Stomach Neoplasms; Triple Negative Breast Neoplasms; Ovarian Neoplasms; Fallopian Tube Neoplasms; Peritoneal Neoplasms; Esophagogastric Junction Neoplasms *Interventions*: Drug: paclitaxel + carboplatin; Drug: carboplatin + etoposide; Drug: gemcitabine + carboplatin; Drug: nab-paclitaxel (paclitaxel-albumin) + carboplatin; Drug: oxaliplatin + 5-fluorouracil (5FU) + leucovorin (... περισσότερα »
Vestibular Disorders after Stapedial Surgery in Patients with Otosclerosis
Vestibular Disorders after Stapedial Surgery in Patients with Otosclerosis: Introduction and Objectives. Vertigo is a described complication of stapedial surgery. Many studies have been conducted to assess the improvement of hearing loss, but there are few studies that assess vestibular function after stapedial surgery. The aim of this study was to evaluate the presence and characterize the vertigo after stapedial surgery. Methods. We conducted a prospective observational study. Patients undergoing stapedial surgery in our hospital between October 2013 and December 2014 were invited...περισσότερα »
Endoscopic ear surgery
Endoscopic ear surgery in Canada: a cross-sectional study: Abstract BackgroundEndoscopic ear surgery is an emerging technique with recent literature highlighting advantages over the traditional microscopic approach. This study aims to characterize the current status of endoscopic ear surgery in Canada and better understand the beliefs and concerns of the otolaryngology – head & neck surgery community regarding this technique. MethodsA cross-sectional survey study of Canadian otolaryngologists was performed. Members of the Canadian Society of Otolaryngology were contacted though...περισσότερα »
Loss of Mitochondrial Tumor Suppressor Genes Expression Is Associated with Unfavorable Clinical Outcome in Head and Neck Squamous Cell Carcinoma: Data from Retrospective Study
Loss of Mitochondrial Tumor Suppressor Genes Expression Is Associated with Unfavorable Clinical Outcome in Head and Neck Squamous Cell Carcinoma: Data from Retrospective Study: by Ishrat Mahjabeen, Mahmood Akhtar Kayani Mitochondrial genes play important roles in cellular energy metabolism, free radical generation, and apoptosis. Dysregulation of these genes have long been suspected to contribute to the generation of reactive oxygen species (ROS), increased proliferation and progression of cancer. A family of orthologues of yeast silent information regulator 3 (SIRT3), 4 (SIRT4) a... περισσότερα »
Diagnostic performance of EUS in predicting advanced cancer among patients with Barrett’s esophagus and high-grade dysplasia/early adenocarcinoma
: systematic review and meta-analysis via ScienceDirect Search: ESOPHAG *Source:*Gastrointestinal Endoscopy, Volume 81, Issue 4 Author(s): Bashar J. Qumseya, Jessica Brown, Merna Abraham, Donna White, Herbert Wolfsen, Neil Gupta, Prashanth Vennalaganti, Prateek Sharma, Michael B. Wallace BackgroundThe role of EUS among patients with Barrett’s esophagus (BE) with high-grade dysplasia (HGD) or suspected mucosal carcinoma is controversial.ObjectiveTo define the role of EUS in detecting advanced disease among patients with BE.DesignSystematic review and meta-analysis.SettingMEDLINE, Emba... περισσότερα »
Meat consumption and cancer risk
: a critical review of published meta-analyses via ScienceDirect Search: ESOPHAG Publication date: January 2016 *Source:*Critical Reviews in Oncology/Hematology, Volume 97 Author(s): Giuseppe Lippi, Camilla Mattiuzzi, Gianfranco Cervellin Dietary habits play a substantial role for increasing or reducing cancer risk. We performed a critical review of scientific literature, to describe the findings of meta-analyses that explored the association between meat consumption and cancer risk. Overall, 42 eligible meta-analyses were included in this review, in which meat consumption was assumed f...περισσότερα »
Endobronchial Treatment of Bronchopleural Fistulas by Using Intrabronchial Valve System
: A Case Series via ScienceDirect Search: ESOPHAG *Source:*Seminars in Thoracic and Cardiovascular Surgery, Volume 27, Issue 2 Author(s): Eitan Podgaetz, Rafael S. Andrade, Felix Zamora, Heidi Gibson, H. Erhan Dincer Air leaks, alveolopleural or bronchopleural fistulas, either spontaneous, iatrogenic, or postsurgical, can be difficult to treat, and if prolonged in spite of proper chest tube thoracostomy they may require surgical or chemical pleurodesis with variable success. Intrabronchial valve (IBV) treatment is minimally invasive and has a potential to shorten the duration of air ...περισσότερα »
Herpetic and candidal esophagitis
A case report of herpetic and candidal esophagitis in an immunocompetent adult via ScienceDirect Search: ESOPHAG *Source:*Asian Pacific Journal of Tropical Biomedicine, Volume 1, Issue 3 Author(s): Vishwanath Sathyanarayanan, Abdul Razak, M Mukhyprana Prabhu, Kavitha Saravu, Pai C Ganesh, Anuradha K Rao Reports of combined candidal and herpetic esophagitis in immunocompetent states are rare and sporadic. A 44-year-old previously healthy lady presented with a one week history of progressive dysphagia, odynophagia and fever. Esophagogastroduodenoscopy (EGD) showed extensive desquamation... περισσότερα »
Midface prosthetic rehabilitation.
Midface prosthetic rehabilitation.: Purpose of review: Midfacial defects resulting from head and neck oncological resections can be addressed by microvascular reconstructive techniques using autologous tissue. In specific indications, however, prosthetic rehabilitation can give a superior aesthetic outcome, combined with a less intensive surgical strain on the patient. In other situations, the combination of both approaches can restore much extended defects satisfactorily. This review lists the indications, technical prerequisites for success, and outcome of midface prosthetic rehab... περισσότερα »
Auris Nasus Larynx
The beneficial effect of Hangesha-shin-to (TJ-014) in gentamicin-induced hair cell loss in the rat cochlea Publication date: Available online 19 January 2016 *Source:*Auris Nasus Larynx Author(s): Katsuki Niwa, Takeshi Matsunobu, Takaomi Kurioka, Daisuke Kamide, Atsushi Tamura, Shin Tadokoro, Yasushi Satoh, Akihiro Shiotani Objective Ototoxic damage caused by aminoglycosides (AG) leads to the loss of cochlear hair cells (HCs). In mammals, mature cochlear HCs are unable to regenerate, and their loss results in permanent hearing deficits. Our objective was to protect the inner ear from...περισσότερα »
Crosshatching incision technique in septoplasty
: Experimental outcomes under actual surgical settings *Source:*Auris Nasus Larynx Author(s): Sung Jae Heo, Jung Soo Kim Objective In previous experiments, the crosshatching incision has been shown to be an effective method for the correction of cartilaginous deviations. Although the settings of the experiments were different from that of septoplasty, the crosshatching incision has been considered a useful method for septoplasty. Therefore, we attempted to determine the efficacy of the crosshatching incision technique under actual septoplasty surgical settings.Methods Commercial pi...περισσότερα »
Auditory phenotype in Stickler syndrome
Auditory phenotype in Stickler syndrome: results of audiometric analysis in 20 patients: AbstractHearing loss in Stickler syndrome has received little attention due to the often more disabling ocular, orofacial and skeletal manifestations. Estimates suggest a global prevalence of sensorineural hearing loss (SNHL) ranging from 50 % to about 100 % though, depending on the underlying Stickler genotype. By performing extensive audiometric analysis in Stickler patients, we aimed to further elucidate the auditory phenotype. Twenty molecularly confirmed Stickler patients (age 10–62 year),... περισσότερα »
Alternate metabolic programs define regional variation of relevant biological features in renal cell carcinoma progression.
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 39 δευτερόλεπτα
Purpose:ccRCC has recently been redefined as a highly heterogeneous disease. In addition to genetic heterogeneity, the tumor displays risk variability for developing metastatic disease, therefore underscoring the urgent need for tissue-based prognostic strategies applicable to the clinical setting. We’ve recently employed the novel positron emission tomography/magnetic resonance (PET/MR) image modality to enrich our understanding of […]
Convergent signaling pathways controlled by LRP1 cytoplasmic and extracellular domains limit cellular cholesterol accumulation Metabolism
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 39 δευτερόλεπτα
The Low Density Lipoprotein receptor-related protein 1 (LRP1) is a ubiquitously expressed cell surface receptor that protects from intracellular cholesterol accumulation. However, the underlying mechanisms are unknown. Here we show that the extracellular α chain of LRP1 mediates TGFβ-induced enhancement of Wnt5a which limits intracellular cholesterol accumulation by inhibiting cholesterol biosynthesis and by promoting cholesterol […]
A Snapshot of the Plant Glycated Proteome: Structural, Functional and Mechanistic Aspects Glycobiology and Extracellular Matrices
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 39 δευτερόλεπτα
Glycation is the reaction of carbonyl compounds (reducing sugars and α-dicarbonyls) with amino acids, lipids, and proteins, yielding early and advanced glycation end-products (AGEs). The AGEs can be formed via degradation of early glycation intermediates (glycoxidation) and by interaction with the products of monosaccharide autoxidation (autoxidative glycosylation). Though formation of these potentially deleterious compounds is […]
Oxidation of a Cysteine Residue in Elongation Factor EF-Tu Reversibly Inhibits Translation in the Cyanobacterium Synechocystis sp. PCC 6803 Plant Biology
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 39 δευτερόλεπτα
Translational elongation is susceptible to inactivation by reactive oxygen species (ROS) in the cyanobacterium Synechocystis sp. PCC 6803, and elongation factor G (EF-G) has been identified as a target of oxidation by ROS. In the present study, we examined the sensitivity to oxidation by ROS of another elongation factor, EF-Tu. The structure of EF-Tu changes […]
Different EGF Receptor Agonists Produce Unique Signatures for the Recruitment of Downstream Signaling Protein Signal Transduction
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 39 δευτερόλεπτα
The EGF receptor can bind seven different agonist ligands. While each agonist appears to stimulate the same suite of downstream signaling proteins, different agonists are capable of inducing distinct responses in the same cell. To determine the basis for these differences, we used luciferase fragment complementation imaging to monitor the recruitment of Cbl, CrkL, Gab1, […]
Type 3 Secretion translocators spontaneously assemble a hexadecameric transmembrane complex Microbiology
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 39 δευτερόλεπτα
A type 3 secretion system is used by many bacterial pathogens to inject proteins into eukaryotic cells. Pathogens insert a translocon complex into the target eukaryotic membrane by secreting two proteins known as translocators. How these translocators form a translocon in the lipid bilayer and why both proteins are required remains elusive. P. aeruginosa translocators […]
NF-kB Essential MOdulator (NEMO) Is Critical for Thyroid Function Signal Transduction
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 39 δευτερόλεπτα
The I-kB kinase (IKK) subunit NEMO/IKKg; (NEMO) is an adapter molecule that is critical for canonical activation of NF-kB, a pleiotropic transcription factor controlling immunity, differentiation, cell growth, tumorigenesis and apoptosis. To explore the functional role of canonical NF-kB signaling in thyroid gland differentiation and function, we have generated a murine strain bearing a genetic […]
Differential activation of innate immune pathways by distinct islet amyloid polypeptide (IAPP) aggregates Immunology
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 39 δευτερόλεπτα
Aggregation of islet amyloid polypeptide (IAPP) contributes to beta cell dysfunction in type 2 diabetes and islet transplantation. Like other amyloidogenic peptides, human IAPP induces macrophage IL-1β secretion by stimulating both the synthesis and processing of proIL-1β, a pro-inflammatory cytokine that – when chronically elevated – impairs beta cell insulin secretion. We sought to determine […]
Biophysical characterization and activity of lymphostatin, a multifunctional virulence factor of attaching & effacing Escherichia coli Microbiology
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 39 δευτερόλεπτα
Attaching & effacing Escherichia coli cause diarrhoea and typically produce lymphostatin (LifA), an inhibitor of mitogen-activated proliferation of lymphocytes and pro-inflammatory cytokine synthesis. A near-identical factor (Efa1) has been reported to mediate adherence of E. coli to epithelial cells. An amino-terminal region of LifA shares homology with the catalytic domain of the large clostridial toxins […]
Structural Determinants of Oligomerization of the Aquaporin-4 Channel Protein Structure and Folding
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 39 δευτερόλεπτα
The aquaporins (AQP) family of integral membrane protein channels mediate cellular water and solute flow. Although qualitative and quantitative differences in channel permeability, selectivity, subcellular localization and trafficking responses have been observed for different members of the AQP family, the signature homotetrameric quaternary structure is conserved. Using a variety of biophysical techniques, we show that […]
Treatment specific utility-weightings are needed for cost–utility analysis in metastatic melanoma: reply from the authors
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 50 δευτερόλεπτα
from #Dermatology via alexandrossfakianakis on Inoreader http://ift.tt/1nkAaXH via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/20dPOC6 via IFTTT
Systematic review of the effectiveness of polyurethane-coated compared with textured silicone implants in breast surgery
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 50 δευτερόλεπτα
Silicone gel implants are used worldwide for breast augmentation and breast reconstruction. Textured silicone implants are the most commonly placed implant, but increasingly, polyurethane-coated implants are used in an attempt to ameliorate the long-term complications associated with implant insertion. from #Aesthetics via alexandrossfakianakis on Inoreader http://ift.tt/1WsYbHL via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via […]
The Medial Sural Artery Perforator Flap in Intra-Oral Reconstruction: A North East Experience
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 50 δευτερόλεπτα
Publication date: Available online 19 January 2016 Source:Journal of Plastic, Reconstructive & Aesthetic Surgery Author(s): R.L. Chalmers, K.M.A. Rahman, S. Young, M. Kennedy, S. Endersby, J.R. Adams, O.A. Ahmed, M. Nugent, M. Ragbir BackgroundThe medial sural artery perforator (MSAP) flap is a fasciocutaneous flap that is gaining popularity for intra-oral reconstructions. The aim of this […]
A necrotizing enterocolitis-associated gut microbiota is already present in the meconium: results of a prospective study
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 50 δευτερόλεπτα
Development of necrotizing enterocolitis has been associated with altered intestinal bacterial colonization. We observed a NEC-associated intestinal microbiota, including Clostridium perfringens, already in meconium samples. Contrariwise, in post-meconium, increased numbers of staphylococci were negatively associated with NEC. from #Infections via alexandrossfakianakis on Inoreader http://ift.tt/1S3mtYk via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis […]
Digital Evaluation of Orbital Development after Self-inflating Hydrogel Expansion in Chinese Children with Congenital Microphthalmia
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 50 δευτερόλεπτα
Publication date: Available online 19 January 2016 Source:Journal of Plastic, Reconstructive & Aesthetic Surgery Author(s): Zhijia Hou, Junfang Xian, Qinglin Chang, Wenbin Wei, Dongmei Li BackgroundAssessment of the growth of bony orbit in children with blind microphthalmia is essential to the management. In this study variables were measured to evaluate the development of the bony […]
Ruxolitinib induces interleukin-17 and ameliorates chronic mucocutaneous candidiasis caused by STAT1 gain-of-function mutation
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 50 δευτερόλεπτα
from #Infections via alexandrossfakianakis on Inoreader http://ift.tt/1S3mv2p via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/23dNzBg via IFTTT
Impact of Policies on the Rise in Sepsis Incidence, 2000-2010
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 50 δευτερόλεπτα
Observed trends in sepsis burden have been significantly impacted by policy and coding practices. Interpretation of and responses to sepsis trends should account for policy-related effects. Reliable sepsis surveillance is critically important to understanding sepsis epidemiology. from #Infections via alexandrossfakianakis on Inoreader http://ift.tt/1NjDUNJ via IFTTT from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on […]
Systematic review of the effectiveness of polyurethane-coated compared with textured silicone implants in breast surgery
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 50 δευτερόλεπτα
Publication date: Available online 19 January 2016 Source:Journal of Plastic, Reconstructive & Aesthetic Surgery Author(s): Paula J. Duxbury, James R. Harvey BackgroundSilicone gel implants are used worldwide for breast augmentation and breast reconstruction. Textured silicone implants are the most commonly placed implant, but increasingly, polyurethane-coated implants are used in an attempt to ameliorate the long-term […]
Differential internalization rates and postendocytic sorting of the norepinephrine and dopamine transporters are controlled by structural elements in the N-termini Membrane Biology
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 50 δευτερόλεπτα
The norepinephrine transporter (NET) mediates reuptake of synaptically released norepinephrine (NE) in central and peripheral noradrenergic neurons. The molecular processes governing availability of NET in the plasma membrane are poorly understood. Here we use the fluorescent cocaine analogue JHC 1-64, as well as several other approaches, to investigate the trafficking itinerary of NET in live […]
Epigenetic Regulation of the Blimp-1 Gene in B Cells Involves Bach2 and Histone Deacetylase 3 Genomics and Proteomics
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 50 δευτερόλεπτα
B lymphocyte-induced maturation protein 1 (Blimp-1) encoded by Prdm1 is a master regulator of plasma cell differentiation. The transcription factor Bach2 represses Blimp-1 expression in B cells to stall terminal differentiation, by which it supports reactions such as class switch recombination of the antibody genes. We found that histone H3 and H4 around the Prdm1 […]
The Medial Sural Artery Perforator Flap in Intra-Oral Reconstruction: A North East Experience
Publication date: Available online 19 January 2016 *Source:*Journal of Plastic, Reconstructive & Aesthetic Surgery Author(s): R.L. Chalmers, K.M.A. Rahman, S. Young, M. Kennedy, S. Endersby, J.R. Adams, O.A. Ahmed, M. Nugent, M. Ragbir BackgroundThe medial sural artery perforator (MSAP) flap is a fasciocutaneous flap that is gaining popularity for intra-oral reconstructions. The aim of this two-centre review was to evaluate the use of the MSAP flap in intra-oral reconstructions and report our experiences.MethodsData was collected prospectively on 35 consecutive intra-oral reconstruc... περισσότερα »
Digital Evaluation of Orbital Development after Self-inflating Hydrogel Expansion in Chinese Children with Congenital Microphthalmia
Publication date: Available online 19 January 2016 *Source:*Journal of Plastic, Reconstructive & Aesthetic Surgery Author(s): Zhijia Hou, Junfang Xian, Qinglin Chang, Wenbin Wei, Dongmei Li BackgroundAssessment of the growth of bony orbit in children with blind microphthalmia is essential to the management. In this study variables were measured to evaluate the development of the bony microphthalmic orbits after treated with self-inflating hydrogel expanders.MethodsRetrospective, interventional case series. Thirteen pediatric patients with congenital unilateral blind microphthalmia wh... περισσότερα »
Systematic review of the effectiveness of polyurethane-coated compared with textured silicone implants in breast surgery
Publication date: Available online 19 January 2016 *Source:*Journal of Plastic, Reconstructive & Aesthetic Surgery Author(s): Paula J. Duxbury, James R. Harvey BackgroundSilicone gel implants are used worldwide for breast augmentation and breast reconstruction. Textured silicone implants are the most commonly placed implant, but increasingly, polyurethane-coated implants are used in an attempt to ameliorate the long-term complications associated with implant insertion.MethodsThis systematic review was conducted according to the Preferred Reporting Items for Systematic Reviews and Met... περισσότερα »
A necrotizing enterocolitis-associated gut microbiota is already present in the meconium: results of a prospective study
Development of necrotizing enterocolitis has been associated with altered intestinal bacterial colonization. We observed a NEC-associated intestinal microbiota, including *Clostridium perfringens,* already in meconium samples. Contrariwise, in post-meconium, increased numbers of staphylococci were negatively associated with NEC. from #Infections via alexandrossfakianakis on Inoreader http://ift.tt/1S3mtYk via IFTTT
Ruxolitinib induces interleukin-17 and ameliorates chronic mucocutaneous candidiasis caused by STAT1 gain-of-function mutation
from #Infections via alexandrossfakianakis on Inoreader http://ift.tt/1S3mv2p via IFTTT
Impact of Policies on the Rise in Sepsis Incidence, 2000-2010
Observed trends in sepsis burden have been significantly impacted by policy and coding practices. Interpretation of and responses to sepsis trends should account for policy-related effects. Reliable sepsis surveillance is critically important to understanding sepsis epidemiology. from #Infections via alexandrossfakianakis on Inoreader http://ift.tt/1NjDUNJ via IFTTT
Visualizing Human Hematopoietic Stem Cell Trafficking In Vivo Using a Zebrafish Xenograft Model
Alexandros G. SfakianakisστοCell and Tissue Research by Alexandros G. SfakianakisΠριν από 55 δευτερόλεπτα
Stem Cells and Development , Vol. 0, No. 0. from Cell via ola Kala on Inoreader http://ift.tt/1Ppko3T via IFTTT
Myogenic Differentiation of Mouse Embryonic Stem Cells That Lack a Functional Pax7 Gene
Alexandros G. SfakianakisστοCell and Tissue Research by Alexandros G. SfakianakisΠριν από 55 δευτερόλεπτα
Stem Cells and Development , Vol. 0, No. 0. from Cell via ola Kala on Inoreader http://ift.tt/1PpkqsD via IFTTT
Visualizing Human Hematopoietic Stem Cell Trafficking In Vivo Using a Zebrafish Xenograft Model
Alexandros G. SfakianakisστοCell and Tissue Research by Alexandros G. SfakianakisΠριν από 55 δευτερόλεπτα
Stem Cells and Development , Vol. 0, No. 0. from Cell via ola Kala on Inoreader http://ift.tt/1Ppko3T via IFTTT
Myogenic Differentiation of Mouse Embryonic Stem Cells That Lack a Functional Pax7 Gene
Alexandros G. SfakianakisστοCell and Tissue Research by Alexandros G. SfakianakisΠριν από 55 δευτερόλεπτα
Stem Cells and Development , Vol. 0, No. 0. from Cell via ola Kala on Inoreader http://ift.tt/1PpkqsD via IFTTT
Location, shape and anatomic relations of the mandibular foramen and the mandibular lingula: a contribution to surgical procedures in the ramus of the mandible
Abstract Purpose The purpose of this study was to obtain morphological parameters of the mandibular foramen (MF) and the mandibular lingula (ML) as well as to use biometric data to locate these structures in the medial aspect of the mandibular ramus and to measure the angle that the inferior alveolar sulcus makes with the posterior margin of the ramus. Methods The sample was composed of 30 dry human mandibles. The quantitative variables were the distances between the MF and the ML, as well as the distances between these structures and the margins of the mandibular ramus. The angl... περισσότερα »
Ebola virus disease: any risk for oral and maxillo-facial surgery? An overview
Abstract The 2014–2015 outbreak of the Ebola virus disease (EVD) in West Africa has been considered a major global health emergency by the WHO. Implications for health care providers including oral and maxillo-facial surgeons have been published by the WHO, the Centers for Disease Control and Prevention (USA), and other medical societies and public health organizations. While the risk of infection with the Ebola virus seems to be rather small in Europe, maxillo-facial and plastic surgeons often travel to Africa to treat patients with facial burns, cleft-lip and palate, and noma. Th... περισσότερα »
Three-dimensional analysis of maxillary stability after Le Fort I osteotomy using hydroxyapatite/poly-L-lactide plate
To evaluate three-dimensional change in maxillary position using biodegradable plates. from #ΓναθοΧειρουργική via xlomafota13 on Inoreader http://ift.tt/1S36gCy via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
ONE stage treatment of Temporomandibular joint complete BONY ankylosis using total joint replacement
Temporomandibular joint ankylosis is a joint disorder due to bone or fibrous adhesion of the joint components that cause loss of function. There are many causes, such as trauma, infections and systemic diseases. To date, no uniform treatment protocol has been established. from #ΓναθοΧειρουργική via xlomafota13 on Inoreader http://ift.tt/20dHxy4 via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
Verrucous carcinoma arising in a port wine stain
We describe a rare case of a verrucous carcinoma, which developed in a port wine stain on the lip of a 70-year-old woman. from #ΓναθοΧειρουργική via xlomafota13 on Inoreader http://ift.tt/20dHvX5 via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
Pre-surgical regional blocks in orthognathic surgery: prospective study evaluating their influence on the intraoperative use of anaesthetics and blood pressure control
In orthognathic surgery, maxillary (CNV2) and mandibular (CNV3) divisions of the trigeminal nerve can be blocked successfully prior to surgery. In this study, it was hypothesized that regional blocks (nerve block over a particular region: bilateral CNV2 and CNV3 divisions of the trigeminal nerve) would decrease the total requirement for intraoperative anaesthetic agents and facilitate the process of hypotensive anaesthesia. Local anaesthesia containing 1/100,000 epinephrine and 10ml 0.5% levobupivacaine was injected into the planned incisions in 50 patients. from #ΓναθοΧειρουργική... περισσότερα »
Differential internalization rates and postendocytic sorting of the norepinephrine and dopamine transporters are controlled by structural elements in the N-termini Membrane Biology
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 1 ώρα
The norepinephrine transporter (NET) mediates reuptake of synaptically released norepinephrine (NE) in central and peripheral noradrenergic neurons. The molecular processes governing availability of NET in the plasma membrane are poorly understood. Here we use the fluorescent cocaine analogue JHC 1-64, as well as several other approaches, to investigate the trafficking itinerary of NET in live […]
Biophysical characterization and activity of lymphostatin, a multifunctional virulence factor of attaching & effacing Escherichia coli Microbiology
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 1 ώρα
Attaching & effacing Escherichia coli cause diarrhoea and typically produce lymphostatin (LifA), an inhibitor of mitogen-activated proliferation of lymphocytes and pro-inflammatory cytokine synthesis. A near-identical factor (Efa1) has been reported to mediate adherence of E. coli to epithelial cells. An amino-terminal region of LifA shares homology with the catalytic domain of the large clostridial toxins […]
Epigenetic Regulation of the Blimp-1 Gene in B Cells Involves Bach2 and Histone Deacetylase 3 Genomics and Proteomics
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 1 ώρα
B lymphocyte-induced maturation protein 1 (Blimp-1) encoded by Prdm1 is a master regulator of plasma cell differentiation. The transcription factor Bach2 represses Blimp-1 expression in B cells to stall terminal differentiation, by which it supports reactions such as class switch recombination of the antibody genes. We found that histone H3 and H4 around the Prdm1 […]
Structural Determinants of Oligomerization of the Aquaporin-4 Channel Protein Structure and Folding
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 1 ώρα
The aquaporins (AQP) family of integral membrane protein channels mediate cellular water and solute flow. Although qualitative and quantitative differences in channel permeability, selectivity, subcellular localization and trafficking responses have been observed for different members of the AQP family, the signature homotetrameric quaternary structure is conserved. Using a variety of biophysical techniques, we show that […]
An Analog-Sensitive Version of the Protein Kinase Slt2 Allows Identification of Novel Targets of the Yeast Cell Wall Integrity Pathway Signal Transduction
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 1 ώρα
The yeast cell wall integrity (CWI) MAPK Slt2 mediates the transcriptional response to cell wall alterations through phosphorylation of transcription factors Rlm1 and SBF. However, the variety of cellular functions regulated by Slt2 suggests the existence of a significant number of still unknown substrates for this kinase. To identify novel Slt2 targets, we generated and […]
Signaling Network Controlling Androgenic Repression of c-Fos in Prostate Adenocarcinoma Cells Gene Regulation
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 1 ώρα
The transcription factor c-Fos controls many important cellular processes including cell growth and apoptosis. c-Fos expression is rapidly elevated in the prostate upon castration-mediated androgen withdrawal through an undefined mechanism. Here we show that androgens (DHT, R1881) suppress c-Fos protein and mRNA expression induced by 12-O-tetradecanoylphorbol-13-acetate (TPA) or EGF in human prostate cancer (PCa) cell […]
Subacute sclerosing panencephalitis in pregnancy
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 1 ώρα
Publication date: Available online 20 January 2016 Source:The Lancet Infectious Diseases Author(s): Michael H Chiu, Bonnie Meatherall, Ana Nikolic, Kristine Cannon, Kevin Fonseca, Jeffrey T Joseph, Judy MacDonald, Kanti Pabbaraju, Raymond Tellier, Sallene Wong, Marcus W Koch We present a case of subacute sclerosing panencephalitis that developed in a previously healthy 29-year-old pregnant woman who […]
Identification of KSHV vIRF1 as a novel interaction partner of human deubiquitinase USP7 Enzymology
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 1 ώρα
Viral Interferon Regulatory Factor 1 (vIRF1), a Kaposis sarcoma herpes virus protein, destabilizes p53 by inhibiting p53 acetylation and Hdm2 phosphorylation. This leads to increased ubiquitination and degradation of p53 by Hdm2, which cripples the cellular p53 mediated antiviral response. Ubiquitin Specific Protease 7 (USP7) deubiquitinates p53 and Hdm2 and regulates their stability. We identified […]
Gatifloxacin versus ceftriaxone for uncomplicated enteric fever in Nepal: an open-label, two-centre, randomised controlled trial
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 1 ώρα
Publication date: Available online 20 January 2016 Source:The Lancet Infectious Diseases Author(s): Amit Arjyal, Buddha Basnyat, Ho Thi Nhan, Samir Koirala, Abhishek Giri, Niva Joshi, Mila Shakya, Kamal Raj Pathak, Saruna Pathak Mahat, Shanti Pradhan Prajapati, Nabin Adhikari, Rajkumar Thapa, Laura Merson, Damodar Gajurel, Kamal Lamsal, Dinesh Lamsal, Bharat Kumar Yadav, Ganesh Shah, Poojan Shrestha, […]
Potential for reduction of burden and local elimination of malaria by reducing Plasmodium falciparum malaria transmission: a mathematical modelling study
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 1 ώρα
Publication date: Available online 20 January 2016 Source:The Lancet Infectious Diseases Author(s): Jamie T Griffin, Samir Bhatt, Marianne E Sinka, Peter W Gething, Michael Lynch, Edith Patouillard, Erin Shutes, Robert D Newman, Pedro Alonso, Richard E Cibulskis, Azra C Ghani BackgroundRapid declines in malaria prevalence, cases, and deaths have been achieved globally during the past […]
Subacute sclerosing panencephalitis in pregnancy
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Publication date: Available online 20 January 2016 Source:The Lancet Infectious Diseases Author(s): Michael H Chiu, Bonnie Meatherall, Ana Nikolic, Kristine Cannon, Kevin Fonseca, Jeffrey T Joseph, Judy MacDonald, Kanti Pabbaraju, Raymond Tellier, Sallene Wong, Marcus W Koch We present a case of subacute sclerosing panencephalitis that developed in a previously healthy 29-year-old pregnant woman who […]
Gatifloxacin versus ceftriaxone for uncomplicated enteric fever in Nepal: an open-label, two-centre, randomised controlled trial
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Publication date: Available online 20 January 2016 Source:The Lancet Infectious Diseases Author(s): Amit Arjyal, Buddha Basnyat, Ho Thi Nhan, Samir Koirala, Abhishek Giri, Niva Joshi, Mila Shakya, Kamal Raj Pathak, Saruna Pathak Mahat, Shanti Pradhan Prajapati, Nabin Adhikari, Rajkumar Thapa, Laura Merson, Damodar Gajurel, Kamal Lamsal, Dinesh Lamsal, Bharat Kumar Yadav, Ganesh Shah, Poojan Shrestha, […]
Potential for reduction of burden and local elimination of malaria by reducing Plasmodium falciparum malaria transmission: a mathematical modelling study
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Publication date: Available online 20 January 2016 Source:The Lancet Infectious Diseases Author(s): Jamie T Griffin, Samir Bhatt, Marianne E Sinka, Peter W Gething, Michael Lynch, Edith Patouillard, Erin Shutes, Robert D Newman, Pedro Alonso, Richard E Cibulskis, Azra C Ghani BackgroundRapid declines in malaria prevalence, cases, and deaths have been achieved globally during the past […]
Troubling news from Asia about treating enteric fever: a coming storm
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Publication date: Available online 20 January 2016 Source:The Lancet Infectious Diseases Author(s): Edward T Ryan from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1SvWKsU via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
How much more malaria could be prevented?
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Publication date: Available online 20 January 2016 Source:The Lancet Infectious Diseases Author(s): Brian Greenwood from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1SvWHxs via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
Acknowledgment to reviewers—2015
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1S2AxRW via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
Three-dimensional reconstruction of coronary arteries and plaque morphology using CT angiography – comparison and registration with IVUS
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Abstract Background The aim of this study is to present a new methodology for three-dimensional (3D) reconstruction of coronary arteries and plaque morphology using Computed Tomography Angiography (CTA). Methods The methodology is summarized in six stages: 1) pre-processing of the initial raw images, 2) rough estimation of the lumen and outer vessel wall borders and […]
Endoscopic ear surgery in Canada: a cross-sectional study
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Endoscopic ear surgery is an emerging technique with recent literature highlighting advantages over the traditional microscopic approach. This study aims to characterize the current status of endoscopic ear su… from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1JgZTtY via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
Psychosocial Adaptation to Chronic Illness and Disability: A Virtue Based Model
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Abstract Purpose Psychosocial adaptation to chronic illness and disability (CID) is an area of study where a positive psychology perspective, especially the study of virtues and character strengths, can be implemented within the rehabilitation framework. A carefully developed theory to guide future interdisciplinary research is now timely. Methods A traditional literature review between philosophy and […]
Number of Comorbidities Negatively Influence Psychological Outcomes of the Elderly Following Hip Fracture in Taiwan
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 1 ώρα
Objective: Hip fracture usually affects psychological functions of the elderly, and comorbidities often interfere with their recovery. However, little is known about the influence of number of comorbidities on their psychological outcomes. Method: Data from a previous study of 461 hip-fractured elders treated at a medical center in northern Taiwan were analyzed by the generalized […]
Location, shape and anatomic relations of the mandibular foramen and the mandibular lingula: a contribution to surgical procedures in the ramus of the mandible
Abstract Purpose The purpose of this study was to obtain morphological parameters of the mandibular foramen (MF) and the mandibular lingula (ML) as well as to use biometric data to locate these structures in the medial aspect of the mandibular ramus and to measure the angle that the inferior alveolar sulcus makes with the posterior margin of the ramus. Methods The sample was composed of 30 dry human mandibles. The quantitative variables were the distances between the MF and the ML, as well as the distances between these structures and the margins of the mandibular ramus. The angl... περισσότερα »
Ebola virus disease: any risk for oral and maxillo-facial surgery? An overview
Abstract The 2014–2015 outbreak of the Ebola virus disease (EVD) in West Africa has been considered a major global health emergency by the WHO. Implications for health care providers including oral and maxillo-facial surgeons have been published by the WHO, the Centers for Disease Control and Prevention (USA), and other medical societies and public health organizations. While the risk of infection with the Ebola virus seems to be rather small in Europe, maxillo-facial and plastic surgeons often travel to Africa to treat patients with facial burns, cleft-lip and palate, and noma. Th... περισσότερα »
Three-dimensional analysis of maxillary stability after Le Fort I osteotomy using hydroxyapatite/poly-L-lactide plate
To evaluate three-dimensional change in maxillary position using biodegradable plates. from OroFacial Medicine via ola Kala on Inoreader http://ift.tt/1S36gCy via IFTTT
ONE stage treatment of Temporomandibular joint complete BONY ankylosis using total joint replacement
Temporomandibular joint ankylosis is a joint disorder due to bone or fibrous adhesion of the joint components that cause loss of function. There are many causes, such as trauma, infections and systemic diseases. To date, no uniform treatment protocol has been established. from OroFacial Medicine via ola Kala on Inoreader http://ift.tt/20dHxy4 via IFTTT
Three-dimensional reconstruction of coronary arteries and plaque morphology using CT angiography – comparison and registration with IVUS
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 2 ώρες
Abstract Background The aim of this study is to present a new methodology for three-dimensional (3D) reconstruction of coronary arteries and plaque morphology using Computed Tomography Angiography (CTA). Methods The methodology is summarized in six stages: 1) pre-processing of the initial raw images, 2) rough estimation of the lumen and outer vessel wall borders and […]
Three-dimensional reconstruction of coronary arteries and plaque morphology using CT angiography – comparison and registration with IVUS
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 2 ώρες
Abstract Background The aim of this study is to present a new methodology for three-dimensional (3D) reconstruction of coronary arteries and plaque morphology using Computed Tomography Angiography (CTA). Methods The methodology is summarized in six stages: 1) pre-processing of the initial raw images, 2) rough estimation of the lumen and outer vessel wall borders and […]
Endoscopic ear surgery in Canada: a cross-sectional study
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 2 ώρες
Endoscopic ear surgery is an emerging technique with recent literature highlighting advantages over the traditional microscopic approach. This study aims to characterize the current status of endoscopic ear su… from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1JgZTtY via IFTTT
Endoscopic ear surgery in Canada: a cross-sectional study
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 2 ώρες
Endoscopic ear surgery is an emerging technique with recent literature highlighting advantages over the traditional microscopic approach. This study aims to characterize the current status of endoscopic ear su… from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1JgZTtY via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174 from #Med Blogs by Alexandros G.Sfakianakis […]
Number of Comorbidities Negatively Influence Psychological Outcomes of the Elderly Following Hip Fracture in Taiwan
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 2 ώρες
Objective: Hip fracture usually affects psychological functions of the elderly, and comorbidities often interfere with their recovery. However, little is known about the influence of number of comorbidities on their psychological outcomes. Method: Data from a previous study of 461 hip-fractured elders treated at a medical center in northern Taiwan were analyzed by the generalized […]
High expression of matrix metalloproteinases: MMP-2 and MMP-9 predicts poor survival outcome in colorectal carcinoma
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 2 ώρες
Future Oncology Ahead of Print. from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1ltCR7r via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174 from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1ZAgSt1 via IFTTT
Gene-expression profiling of localized prostate cancer: still miles to go before we sleep
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 2 ώρες
Future Oncology Ahead of Print. from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1S3bbDg via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174 from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1S3bZYP via IFTTT
خزعة الثدي الجراحي جراحة
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 2 ώρες
خزعة الثدي الجراحي جراحة from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader https://www.youtube.com/watch?v=5kzn2qEau04 via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174 from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1ZAgQ4p via IFTTT
Design of the randomized, Phase III, QUAZAR AML Maintenance trial of CC-486 (oral azacitidine) maintenance therapy in acute myeloid leukemia
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 2 ώρες
Future Oncology Ahead of Print. from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1ltCQk2 via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174 from #Med Blogs by Alexandros G.Sfakianakis via Alexandros G.Sfakianakis on Inoreader http://ift.tt/1T2YcT6 via IFTTT
The predictive capacity of apparent diffusion coefficient (ADC) in response assessment of brain metastases following radiation
fasoladaellinikiστοOTOLARYNGOLOGY LIFELONG LEARNING : OTOLARYNGOLOGY BY ALEXANDROS SFAKIANAKIS,GREECE CRETE,ANAPAFSEOS 5 AGIOS NIKOLAOS 72100,TEL : 00302841026182,00306932607174Πριν από 2 ώρες
Abstract To investigate the predictive capacity of the apparent diffusion coefficient (ADC) as a biomarker of radiation response in brain metastases. Seventy brain metastases from 42 patients treated with either stereotactic radiosurgery or whole brain radiotherapy were imaged at baseline, 1 week, and 1 month post-treatment using diffusion-weighted MRI. Mean and median relative ADC for […]
High expression of matrix metalloproteinases: MMP-2 and MMP-9 predicts poor survival outcome in colorectal carcinoma
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 2 ώρες
Future Oncology Ahead of Print. from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1ltCR7r via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
Gene-expression profiling of localized prostate cancer: still miles to go before we sleep
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 2 ώρες
Future Oncology Ahead of Print. from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1S3bbDg via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
Design of the randomized, Phase III, QUAZAR AML Maintenance trial of CC-486 (oral azacitidine) maintenance therapy in acute myeloid leukemia
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 2 ώρες
Future Oncology Ahead of Print. from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader http://ift.tt/1ltCQk2 via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
خزعة الثدي الجراحي جراحة
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 2 ώρες
خزعة الثدي الجراحي جراحة from #Medicine-SfakianakisAlexandros via o.lakala70 on Inoreader https://www.youtube.com/watch?v=5kzn2qEau04 via IFTTT Medicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174
The predictive capacity of apparent diffusion coefficient (ADC) in response assessment of brain metastases following radiation
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 2 ώρες
Abstract To investigate the predictive capacity of the apparent diffusion coefficient (ADC) as a biomarker of radiation response in brain metastases. Seventy brain metastases from 42 patients treated with either stereotactic radiosurgery or whole brain radiotherapy were imaged at baseline, 1 week, and 1 month post-treatment using diffusion-weighted MRI. Mean and median relative ADC for […]
A Strength-Based Arts and Play Support Program for Young Survivors in Post-Quake China: Effects on Self-Efficacy, Peer Support, and Anxiety
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 2 ώρες
A year after the earthquake in Sichuan, China, a strength-based arts and play support program was launched to promote the well-being of young survivors, and this study was designed to examine its effectiveness. It was hypothesized that participation in the program would have direct positive effects on general self-efficacy and peer support, and that these […]
Dovitinib acts as a novel radiosensitizer in hepatocellular carcinoma via targeting SHP-1/STAT3 signaling
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 2 ώρες
Publication date: Available online 20 January 2016 Source:International Journal of Radiation Oncology*Biology*Physics Author(s): Chao-Yuan Huang, Wei-Tien Tai, Szu-Yuan Wu, Chih-Ting Shih, Min-Hsuan Chen, Chiung-Wen Kuo, Chung-Wai Shiau, Man-Hsin Hung, Kuen-Feng Chen PurposeHepatocellular carcinoma (HCC) is one of the most lethal human malignancies and curative therapy is not an option for most patients. There is growing […]
Can we advance proton therapy for prostate? Considering alternative beam angles and RBE variations when comparing against IMRT
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 2 ώρες
Publication date: Available online 19 January 2016 Source:International Journal of Radiation Oncology*Biology*Physics Author(s): Tracy Underwood, Drosoula Giantsoudi, Maryam Moteabbed, Anthony Zietman, Jason Efstathiou, Harald Paganetti, Hsiao-Ming Lu Purpose/Objective(s)For prostate treatments, robust evidence regarding the superiority of either IMRT or proton therapy is currently lacking. In this study we investigate the circumstances under which proton therapy […]
Carbon-ion Pencil Beam Scanning Treatment with Gated Markerless Tumor Tracking: an Analysis of Positional Accuracy
medicinesfakianakisστοMedicine by Alexandros G.Sfakianakis,Anapafseos 5 Agios Nikolaos,Crete 72100,Greece,tel :00302841026182 & 00306932607174Πριν από 2 ώρες
Publication date: Available online 20 January 2016 Source:International Journal of Radiation Oncology*Biology*Physics Author(s): Shinichiro Mori, Masataka Karube, Toshiyuki Shirai, Minoru Tajiri, Takuro Takekoshi, Kentaro Miki, Yurika Shiraishi, Katsuyuki Tanimoto, Kouichi Shibayama, Shigeo Yasuda, Naoyoshi Yamamoto, Shigeru Yamada, Hiroshi Tsuji, Koji Noda, Tadashi Kamada PurposeHaving implemented amplitude-based respiratory gating for scanned carbon-ion beam therapy, we sought […]
